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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28381348
log Bayes Factor = 17.5226
Chromosome 6   position 31,708,910  (GRCh37) Explore rs28381348 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.999 0.001 0.000
E11 Non-insulin-dependent diabetes mellitus
0.999 0.001 0.000
E10.3 With ophthalmic complications
0.999 0.001 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.997 0.003 0.000
E11.9 Without complications
0.995 0.005 0.000
E11.3 With ophthalmic complications
0.958 0.042 0.000
E10.4 With neurological complications
0.930 0.070 0.000
E10.5 With peripheral circulatory complications
0.927 0.073 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.920 0.080 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.913 0.087 0.000
E10.1 With ketoacidosis
0.907 0.093 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.897 0.103 0.000
M06 Other rheumatoid arthritis
0.896 0.104 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.857 0.143 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.846 0.154 0.000
E11.5 With peripheral circulatory complications
0.832 0.168 0.000
E11.1 With ketoacidosis
0.820 0.180 0.000
M05-M14 Inflammatory polyarthropathies
0.780 0.220 0.000
M05 Seropositive rheumatoid arthritis
0.772 0.228 0.000
E10.2 With renal complications
0.772 0.228 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.768 0.232 0.000
M06.3 Rheumatoid nodule
0.762 0.238 0.000
E11.8 With unspecified complications
0.761 0.239 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.756 0.244 0.000
E11.0 With coma
0.726 0.274 0.000
E10.8 With unspecified complications
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E10.6 With other specified complications
0.717 0.283 0.000
E10.0 With coma
0.717 0.283 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.283 0.000
E11.7 With multiple complications
0.716 0.284 0.000
E11.6 With other specified complications
0.716 0.284 0.000
E14 Unspecified diabetes mellitus
0.707 0.293 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.693 0.307 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.690 0.310 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.682 0.317 0.000
E11.4 With neurological complications
0.674 0.326 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.670 0.330 0.000
M06.34 Rheumatoid nodule (Hand)
0.667 0.333 0.000
E16 Other disorders of pancreatic internal secretion
0.653 0.347 0.000
E20-E35 Disorders of other endocrine glands
0.647 0.353 0.000
M06.8 Other specified rheumatoid arthritis
0.642 0.358 0.000
M06.4 Inflammatory polyarthropathy
0.642 0.358 0.000
M06.2 Rheumatoid bursitis
0.642 0.358 0.000
M06.1 Adult-onset Still's disease
0.642 0.358 0.000
E16.2 Hypoglycaemia, unspecified
0.642 0.358 0.000
E11.2 With renal complications
0.639 0.360 0.000
E13 Other specified diabetes mellitus
0.639 0.360 0.000
E14.3 With ophthalmic complications
0.596 0.404 0.000
M06.0 Seronegative rheumatoid arthritis
0.585 0.415 0.000
M14 Arthropathies in other diseases classified elsewhere
0.559 0.441 0.000
M12 Other specific arthropathies
0.559 0.441 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.559 0.441 0.000
M08 Juvenile arthritis
0.559 0.441 0.000
M10 Gout
0.558 0.442 0.000
M05.8 Other seropositive rheumatoid arthritis
0.554 0.446 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.554 0.446 0.000
M05.2 Rheumatoid vasculitis
0.554 0.446 0.000
M05.1 Rheumatoid lung disease
0.554 0.446 0.000
M05.0 Felty's syndrome
0.554 0.446 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.550 0.450 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.550 0.450 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.550 0.450 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.550 0.450 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.550 0.450 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.550 0.450 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.550 0.450 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.550 0.450 0.000
E22 Hyperfunction of pituitary gland
0.548 0.452 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.548 0.452 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.546 0.453 0.000
M06.38 Rheumatoid nodule (Other)
0.546 0.453 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.546 0.453 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.546 0.453 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.546 0.453 0.000
M06.33 Rheumatoid nodule (Forearm)
0.546 0.453 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.546 0.453 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.546 0.453 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.546 0.453 0.000
M11 Other crystal arthropathies
0.522 0.478 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E23 Hypofunction and other disorders of pituitary gland
0.511 0.489 0.000
E14.8 With unspecified complications
0.507 0.493 0.000
E14.7 With multiple complications
0.507 0.493 0.000
E14.6 With other specified complications
0.507 0.493 0.000
E14.5 With peripheral circulatory complications
0.507 0.493 0.000
E14.4 With neurological complications
0.507 0.493 0.000
E14.2 Withrenal complications
0.507 0.493 0.000
E14.1 With ketoacidosis
0.507 0.493 0.000
E14.0 With coma
0.507 0.493 0.000
E29 Testicular dysfunction
0.503 0.497 0.000
E34 Other endocrine disorders
0.501 0.499 0.000
E40-E46 Malnutrition
0.497 0.503 0.000
E15 Nondiabetic hypoglycaemic coma
0.480 0.520 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.468 0.532 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.468 0.532 0.000
E16.4 Abnormal secretion of gastrin
0.468 0.532 0.000
E16.3 Increased secretion of glucagon
0.468 0.532 0.000
E16.1 Other hypoglycaemia
0.468 0.532 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.468 0.532 0.000
M07 Psoriatic and enteropathic arthropathies
0.466 0.534 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.464 0.536 0.000
E32 Diseases of thymus
0.464 0.536 0.000
E31 Polyglandular dysfunction
0.464 0.536 0.000
E30 Disorders of puberty, not elsewhere classified
0.464 0.536 0.000
E26 Hyperaldosteronism
0.464 0.536 0.000
E25 Adrenogenital disorders
0.464 0.536 0.000
E24 Cushing's syndrome
0.464 0.536 0.000
E20 Hypoparathyroidism
0.464 0.536 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.460 0.539 0.000
M06.18 Adult-onset Still's disease (Other)
0.460 0.539 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.460 0.539 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.460 0.539 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.460 0.539 0.000
M06.14 Adult-onset Still's disease (Hand)
0.460 0.539 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.460 0.539 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.460 0.539 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.460 0.539 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.460 0.539 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.460 0.539 0.000
M06.28 Rheumatoid bursitis (Other)
0.460 0.539 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.460 0.539 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.460 0.539 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.460 0.539 0.000
M06.24 Rheumatoid bursitis (Hand)
0.460 0.539 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.460 0.539 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.460 0.539 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.460 0.539 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.460 0.539 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.460 0.539 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.460 0.539 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.460 0.539 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.460 0.539 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.460 0.539 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.460 0.539 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.460 0.539 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.460 0.539 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.460 0.539 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.460 0.539 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.460 0.539 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.460 0.539 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.460 0.539 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.460 0.539 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.460 0.539 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.460 0.539 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.460 0.539 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.460 0.539 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.460 0.539 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.460 0.539 0.000
E13.8 With unspecified complications
0.458 0.541 0.000
E13.7 With multiple complications
0.458 0.541 0.000
E13.6 With other specified complications
0.458 0.541 0.000
E13.5 With peripheral circulatory complications
0.458 0.541 0.000
E13.4 With neurological complications
0.458 0.541 0.000
E13.3 With ophthalmic complications
0.458 0.541 0.000
E13.2 With renal complications
0.458 0.541 0.000
E13.1 With ketoacidosis
0.458 0.541 0.000
E13.0 With coma
0.458 0.541 0.000
E21.3 Hyperparathyroidism, unspecified
0.458 0.542 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.455 0.544 0.000
E50-E64 Other nutritional deficiencies
0.455 0.545 0.000
E28 Ovarian dysfunction
0.443 0.557 0.000
E65-E68 Obesity and other hyperalimentation
0.436 0.564 0.000
E22.1 Hyperprolactinaemia
0.429 0.571 0.000
E27 Other disorders of adrenal gland
0.429 0.571 0.000
E21.0 Primary hyperparathyroidism
0.424 0.576 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.419 0.581 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.419 0.581 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.419 0.581 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.419 0.581 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.419 0.581 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.419 0.581 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.419 0.581 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.419 0.581 0.000
K90.0 Coeliac disease
0.000 0.581 0.419
E23.0 Hypopituitarism
0.413 0.587 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.411 0.589 0.000
M08.9 Juvenile arthritis, unspecified
0.401 0.599 0.000
M08.8 Other juvenile arthritis
0.401 0.599 0.000
M08.4 Pauciarticular juvenile arthritis
0.401 0.599 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.401 0.599 0.000
M08.2 Juvenile arthritis with systemic onset
0.401 0.599 0.000
M08.1 Juvenile ankylosing spondylitis
0.401 0.599 0.000
M08.0 Juvenile rheumatoid arthritis
0.401 0.599 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.401 0.599 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.401 0.599 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.401 0.599 0.000
M09.0 Juvenile arthritis in psoriasis
0.401 0.599 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.401 0.599 0.000
M12.5 Traumatic arthropathy
0.401 0.599 0.000
M12.4 Intermittent hydrarthrosis
0.401 0.599 0.000
M12.3 Palindromic rheumatism
0.401 0.599 0.000
M12.2 Villonodular synovitis (pigmented)
0.401 0.599 0.000
M12.1 Kaschin-Beck disease
0.401 0.599 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.401 0.599 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.401 0.599 0.000
M14.6 Neuropathic arthropathy
0.401 0.599 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.401 0.599 0.000
M14.4 Arthropathy in amyloidosis
0.401 0.599 0.000
M14.3 Lipoid dermatoarthritis
0.401 0.599 0.000
M14.2 Diabetic arthropathy
0.401 0.599 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.401 0.599 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.401 0.599 0.000
M10.4 Other secondary gout
0.400 0.600 0.000
M10.3 Gout due to impairment of renal function
0.400 0.600 0.000
M10.2 Drug-induced gout
0.400 0.600 0.000
M10.1 Lead-induced gout
0.400 0.600 0.000
M10.0 Idiopathic gout
0.400 0.600 0.000
E29.1 Testicular hypofunction
0.399 0.601 0.000
M10.9 Gout, unspecified
0.399 0.601 0.000
M05.09 Felty's syndrome (Site unspecified)
0.397 0.603 0.000
M05.08 Felty's syndrome (Other)
0.397 0.603 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.397 0.603 0.000
M05.06 Felty's syndrome (Lower leg)
0.397 0.603 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.397 0.603 0.000
M05.04 Felty's syndrome (Hand)
0.397 0.603 0.000
M05.03 Felty's syndrome (Forearm)
0.397 0.603 0.000
M05.02 Felty's syndrome (Upper arm)
0.397 0.603 0.000
M05.01 Felty's syndrome (Shoulder region)
0.397 0.603 0.000
M05.00 Felty's syndrome (Multiple sites)
0.397 0.603 0.000
M05.19 Rheumatoid lung disease (Site unspecified)
0.397 0.603 0.000
M05.18 Rheumatoid lung disease (Other)
0.397 0.603 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.397 0.603 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.397 0.603 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.397 0.603 0.000
M05.14 Rheumatoid lung disease (Hand)
0.397 0.603 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.397 0.603 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.397 0.603 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.397 0.603 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.397 0.603 0.000
M05.29 Rheumatoid vasculitis (Site unspecified)
0.397 0.603 0.000
M05.28 Rheumatoid vasculitis (Other)
0.397 0.603 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.397 0.603 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.397 0.603 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.397 0.603 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.397 0.603 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.397 0.603 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.397 0.603 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.397 0.603 0.000
M05.20 Rheumatoid vasculitis (Multiple sites)
0.397 0.603 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.397 0.603 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.397 0.603 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.397 0.603 0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.397 0.603 0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.397 0.603 0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.397 0.603 0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.397 0.603 0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.397 0.603 0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.397 0.603 0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.397 0.603 0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.397 0.603 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.397 0.603 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.397 0.603 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.397 0.603 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.397 0.603 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.397 0.603 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.397 0.603 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.397 0.603 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.397 0.603 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.397 0.603 0.000
E34.0 Carcinoid syndrome
0.396 0.604 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.393 0.607 0.000
E22.8 Other hyperfunction of pituitary gland
0.393 0.607 0.000
E22.0 Acromegaly and pituitary gigantism
0.393 0.607 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.393 0.607 0.000
E21.4 Other specified disorders of parathyroid gland
0.393 0.607 0.000
E21.2 Other hyperparathyroidism
0.393 0.607 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.393 0.607 0.000
E13.9 Without complications
0.381 0.618 0.000
M11.9 Crystal arthropathy, unspecified
0.375 0.625 0.000
M11.8 Other specified crystal arthropathies
0.375 0.625 0.000
M11.1 Familial chondrocalcinosis
0.375 0.625 0.000
M11.0 Hydroxyapatite deposition disease
0.375 0.625 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.372 0.628 0.000
E23.7 Disorder of pituitary gland, unspecified
0.366 0.634 0.000
E23.6 Other disorders of pituitary gland
0.366 0.634 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.366 0.634 0.000
E23.2 Diabetes insipidus
0.366 0.634 0.000
E23.1 Drug-induced hypopituitarism
0.366 0.634 0.000
E29.9 Testicular dysfunction, unspecified
0.360 0.639 0.000
E29.8 Other testicular dysfunction
0.360 0.639 0.000
E29.0 Testicular hyperfunction
0.360 0.639 0.000
E34.9 Endocrine disorder, unspecified
0.359 0.641 0.000
E34.8 Other specified endocrine disorders
0.359 0.641 0.000
E34.5 Androgen resistance syndrome
0.359 0.641 0.000
E34.4 Constitutional tall stature
0.359 0.641 0.000
E34.3 Short stature, not elsewhere classified
0.359 0.641 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.359 0.641 0.000
E34.1 Other hypersecretion of intestinal hormones
0.359 0.641 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.357 0.643 0.000
E46 Unspecified protein-energy malnutrition
0.357 0.643 0.000
E45 Retarded development following protein-energy malnutrition
0.357 0.643 0.000
E43 Unspecified severe protein-energy malnutrition
0.357 0.643 0.000
E42 Marasmic kwashiorkor
0.357 0.643 0.000
E41 Nutritional marasmus
0.357 0.643 0.000
E40 Kwashiorkor
0.357 0.643 0.000
E27.9 Disorder of adrenal gland, unspecified
0.342 0.658 0.000
M11.2 Other chondrocalcinosis
0.338 0.662 0.000
M13 Other arthritis
0.335 0.665 0.000
M07.6 Other enteropathic arthropathies
0.334 0.665 0.000
M07.5 Arthropathy in ulcerative colitis
0.334 0.665 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.334 0.665 0.000
M07.2 Psoriatic spondylitis
0.334 0.665 0.000
M07.1 Arthritis mutilans
0.334 0.665 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.334 0.665 0.000
E20.9 Hypoparathyroidism, unspecified
0.333 0.667 0.000
E20.8 Other hypoparathyroidism
0.333 0.667 0.000
E20.1 Pseudohypoparathyroidism
0.333 0.667 0.000
E20.0 Idiopathic hypoparathyroidism
0.333 0.667 0.000
E24.9 Cushing's syndrome, unspecified
0.333 0.667 0.000
E24.8 Other Cushing's syndrome
0.333 0.667 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.333 0.667 0.000
E24.3 Ectopic ACTH syndrome
0.333 0.667 0.000
E24.2 Drug-induced Cushing's syndrome
0.333 0.667 0.000
E24.1 Nelson's syndrome
0.333 0.667 0.000
E24.0 Pituitary-dependent Cushing's disease
0.333 0.667 0.000
E25.9 Adrenogenital disorder, unspecified
0.333 0.667 0.000
E25.8 Other adrenogenital disorders
0.333 0.667 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.333 0.667 0.000
E26.9 Hyperaldosteronism, unspecified
0.333 0.667 0.000
E26.8 Other hyperaldosteronism
0.333 0.667 0.000
E26.1 Secondary hyperaldosteronism
0.333 0.667 0.000
E26.0 Primary hyperaldosteronism
0.333 0.667 0.000
E30.9 Disorder of puberty, unspecified
0.333 0.667 0.000
E30.8 Other disorders of puberty
0.333 0.667 0.000
E30.1 Precocious puberty
0.333 0.667 0.000
E30.0 Delayed puberty
0.333 0.667 0.000
E31.9 Polyglandular dysfunction, unspecified
0.333 0.667 0.000
E31.8 Other polyglandular dysfunction
0.333 0.667 0.000
E31.1 Polyglandular hyperfunction
0.333 0.667 0.000
E31.0 Autoimmune polyglandular failure
0.333 0.667 0.000
E32.9 Disease of thymus, unspecified
0.333 0.667 0.000
E32.8 Other diseases of thymus
0.333 0.667 0.000
E32.1 Abscess of thymus
0.333 0.667 0.000
E32.0 Persistent hyperplasia of thymus
0.333 0.667 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.333 0.667 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.333 0.667 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.333 0.667 0.000
E14.9 Without complications
0.331 0.669 0.000
E27.8 Other specified disorders of adrenal gland
0.330 0.670 0.000
E65 Localised adiposity
0.330 0.670 0.000
M10.93 Gout, unspecified (Forearm)
0.328 0.672 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.326 0.674 0.000
E63 Other nutritional deficiencies
0.326 0.674 0.000
E56 Other vitamin deficiencies
0.326 0.674 0.000
E51 Thiamine deficiency
0.326 0.674 0.000
E50 Vitamin A deficiency
0.326 0.674 0.000
E60 Dietary zinc deficiency
0.326 0.674 0.000
E59 Dietary selenium deficiency
0.326 0.674 0.000
E58 Dietary calcium deficiency
0.326 0.674 0.000
E54 Ascorbic acid deficiency
0.326 0.674 0.000
E52 Niacin deficiency [pellagra]
0.326 0.674 0.000
E61 Deficiency of other nutrient elements
0.322 0.678 0.000
E28.9 Ovarian dysfunction, unspecified
0.317 0.682 0.000
E28.8 Other ovarian dysfunction
0.317 0.682 0.000
E28.3 Primary ovarian failure
0.317 0.682 0.000
E28.1 Androgen excess
0.317 0.682 0.000
E28.0 Oestrogen excess
0.317 0.682 0.000
E55 Vitamin D deficiency
0.316 0.684 0.000
E67 Other hyperalimentation
0.313 0.687 0.000
E68 Sequelae of hyperalimentation
0.313 0.687 0.000
E27.5 Adrenomedullary hyperfunction
0.307 0.692 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.307 0.692 0.000
E27.2 Addisonian crisis
0.307 0.692 0.000
E27.0 Other adrenocortical overactivity
0.307 0.692 0.000
H36.0 Diabetic retinopathy
0.305 0.695 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.304 0.696 0.000
E53 Deficiency of other B group vitamins
0.301 0.699 0.000
E28.2 Polycystic ovarian syndrome
0.296 0.704 0.000
M08.09 Juvenile rheumatoid arthritis (Site unspecified)
0.287 0.712 0.000
M08.08 Juvenile rheumatoid arthritis (Other)
0.287 0.712 0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)
0.287 0.712 0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)
0.287 0.712 0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)
0.287 0.712 0.000
M08.04 Juvenile rheumatoid arthritis (Hand)
0.287 0.712 0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)
0.287 0.712 0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)
0.287 0.712 0.000
M08.01 Juvenile rheumatoid arthritis (Shoulder region)
0.287 0.712 0.000
M08.00 Juvenile rheumatoid arthritis (Multiple sites)
0.287 0.712 0.000
M08.19 Juvenile ankylosing spondylitis (Site unspecified)
0.287 0.712 0.000
M08.18 Juvenile ankylosing spondylitis (Other)
0.287 0.712 0.000
M08.17 Juvenile ankylosing spondylitis (Ankle and foot)
0.287 0.712 0.000
M08.16 Juvenile ankylosing spondylitis (Lower leg)
0.287 0.712 0.000
M08.15 Juvenile ankylosing spondylitis (Pelvic region and thigh)
0.287 0.712 0.000
M08.14 Juvenile ankylosing spondylitis (Hand)
0.287 0.712 0.000
M08.13 Juvenile ankylosing spondylitis (Forearm)
0.287 0.712 0.000
M08.12 Juvenile ankylosing spondylitis (Upper arm)
0.287 0.712 0.000
M08.11 Juvenile ankylosing spondylitis (Shoulder region)
0.287 0.712 0.000
M08.10 Juvenile ankylosing spondylitis (Multiple sites)
0.287 0.712 0.000
M08.29 Juvenile arthritis with systemic onset (Site unspecified)
0.287 0.712 0.000
M08.28 Juvenile arthritis with systemic onset (Other)
0.287 0.712 0.000
M08.27 Juvenile arthritis with systemic onset (Ankle and foot)
0.287 0.712 0.000
M08.26 Juvenile arthritis with systemic onset (Lower leg)
0.287 0.712 0.000
M08.25 Juvenile arthritis with systemic onset (Pelvic region and thigh)
0.287 0.712 0.000
M08.24 Juvenile arthritis with systemic onset (Hand)
0.287 0.712 0.000
M08.23 Juvenile arthritis with systemic onset (Forearm)
0.287 0.712 0.000
M08.22 Juvenile arthritis with systemic onset (Upper arm)
0.287 0.712 0.000
M08.21 Juvenile arthritis with systemic onset (Shoulder region)
0.287 0.712 0.000
M08.20 Juvenile arthritis with systemic onset (Multiple sites)
0.287 0.712 0.000
M08.39 Juvenile polyarthritis (seronegative) (Site unspecified)
0.287 0.712 0.000
M08.38 Juvenile polyarthritis (seronegative) (Other)
0.287 0.712 0.000
M08.37 Juvenile polyarthritis (seronegative) (Ankle and foot)
0.287 0.712 0.000
M08.36 Juvenile polyarthritis (seronegative) (Lower leg)
0.287 0.712 0.000
M08.35 Juvenile polyarthritis (seronegative) (Pelvic region and thigh)
0.287 0.712 0.000
M08.34 Juvenile polyarthritis (seronegative) (Hand)
0.287 0.712 0.000
M08.33 Juvenile polyarthritis (seronegative) (Forearm)
0.287 0.712 0.000
M08.32 Juvenile polyarthritis (seronegative) (Upper arm)
0.287 0.712 0.000
M08.31 Juvenile polyarthritis (seronegative) (Shoulder region)
0.287 0.712 0.000
M08.30 Juvenile polyarthritis (seronegative) (Multiple sites)
0.287 0.712 0.000
M08.49 Pauciarticular juvenile arthritis (Site unspecified)
0.287 0.712 0.000
M08.48 Pauciarticular juvenile arthritis (Other)
0.287 0.712 0.000
M08.47 Pauciarticular juvenile arthritis (Ankle and foot)
0.287 0.712 0.000
M08.46 Pauciarticular juvenile arthritis (Lower leg)
0.287 0.712 0.000
M08.45 Pauciarticular juvenile arthritis (Pelvic region and thigh)
0.287 0.712 0.000
M08.44 Pauciarticular juvenile arthritis (Hand)
0.287 0.712 0.000
M08.43 Pauciarticular juvenile arthritis (Forearm)
0.287 0.712 0.000
M08.42 Pauciarticular juvenile arthritis (Upper arm)
0.287 0.712 0.000
M08.41 Pauciarticular juvenile arthritis (Shoulder region)
0.287 0.712 0.000
M08.40 Pauciarticular juvenile arthritis (Multiple sites)
0.287 0.712 0.000
M08.89 Other juvenile arthritis (Site unspecified)
0.287 0.712 0.000
M08.88 Other juvenile arthritis (Other)
0.287 0.712 0.000
M08.87 Other juvenile arthritis (Ankle and foot)
0.287 0.712 0.000
M08.86 Other juvenile arthritis (Lower leg)
0.287 0.712 0.000
M08.85 Other juvenile arthritis (Pelvic region and thigh)
0.287 0.712 0.000
M08.84 Other juvenile arthritis (Hand)
0.287 0.712 0.000
M08.83 Other juvenile arthritis (Forearm)
0.287 0.712 0.000
M08.82 Other juvenile arthritis (Upper arm)
0.287 0.712 0.000
M08.81 Other juvenile arthritis (Shoulder region)
0.287 0.712 0.000
M08.80 Other juvenile arthritis (Multiple sites)
0.287 0.712 0.000
M08.99 Juvenile arthritis, unspecified (Site unspecified)
0.287 0.712 0.000
M08.98 Juvenile arthritis, unspecified (Other)
0.287 0.712 0.000
M08.97 Juvenile arthritis, unspecified (Ankle and foot)
0.287 0.712 0.000
M08.96 Juvenile arthritis, unspecified (Lower leg)
0.287 0.712 0.000
M08.95 Juvenile arthritis, unspecified (Pelvic region and thigh)
0.287 0.712 0.000
M08.94 Juvenile arthritis, unspecified (Hand)
0.287 0.712 0.000
M08.93 Juvenile arthritis, unspecified (Forearm)
0.287 0.712 0.000
M08.92 Juvenile arthritis, unspecified (Upper arm)
0.287 0.712 0.000
M08.91 Juvenile arthritis, unspecified (Shoulder region)
0.287 0.712 0.000
M08.90 Juvenile arthritis, unspecified (Multiple sites)
0.287 0.712 0.000
M09.09 Juvenile arthritis in psoriasis (Site unspecified)
0.287 0.712 0.000
M09.08 Juvenile arthritis in psoriasis (Other)
0.287 0.712 0.000
M09.07 Juvenile arthritis in psoriasis (Ankle and foot)
0.287 0.712 0.000
M09.06 Juvenile arthritis in psoriasis (Lower leg)
0.287 0.712 0.000
M09.05 Juvenile arthritis in psoriasis (Pelvic region and thigh)
0.287 0.712 0.000
M09.04 Juvenile arthritis in psoriasis (Hand)
0.287 0.712 0.000
M09.03 Juvenile arthritis in psoriasis (Forearm)
0.287 0.712 0.000
M09.02 Juvenile arthritis in psoriasis (Upper arm)
0.287 0.712 0.000
M09.01 Juvenile arthritis in psoriasis (Shoulder region)
0.287 0.712 0.000
M09.00 Juvenile arthritis in psoriasis (Multiple sites)
0.287 0.712 0.000
M09.19 Juvenile arthritis in Crohn's disease [regional enteritis] (Site unspecified)
0.287 0.712 0.000
M09.18 Juvenile arthritis in Crohn's disease [regional enteritis] (Other)
0.287 0.712 0.000
M09.17 Juvenile arthritis in Crohn's disease [regional enteritis] (Ankle and foot)
0.287 0.712 0.000
M09.16 Juvenile arthritis in Crohn's disease [regional enteritis] (Lower leg)
0.287 0.712 0.000
M09.15 Juvenile arthritis in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.287 0.712 0.000
M09.14 Juvenile arthritis in Crohn's disease [regional enteritis] (Hand)
0.287 0.712 0.000
M09.13 Juvenile arthritis in Crohn's disease [regional enteritis] (Forearm)
0.287 0.712 0.000
M09.12 Juvenile arthritis in Crohn's disease [regional enteritis] (Upper arm)
0.287 0.712 0.000
M09.11 Juvenile arthritis in Crohn's disease [regional enteritis] (Shoulder region)
0.287 0.712 0.000
M09.10 Juvenile arthritis in Crohn's disease [regional enteritis] (Multiple sites)
0.287 0.712 0.000
M09.29 Juvenile arthritis in ulcerative colitis (Site unspecified)
0.287 0.712 0.000
M09.28 Juvenile arthritis in ulcerative colitis (Other)
0.287 0.712 0.000
M09.27 Juvenile arthritis in ulcerative colitis (Ankle and foot)
0.287 0.712 0.000
M09.26 Juvenile arthritis in ulcerative colitis (Lower leg)
0.287 0.712 0.000
M09.25 Juvenile arthritis in ulcerative colitis (Pelvic region and thigh)
0.287 0.712 0.000
M09.24 Juvenile arthritis in ulcerative colitis (Hand)
0.287 0.712 0.000
M09.23 Juvenile arthritis in ulcerative colitis (Forearm)
0.287 0.712 0.000
M09.22 Juvenile arthritis in ulcerative colitis (Upper arm)
0.287 0.712 0.000
M09.21 Juvenile arthritis in ulcerative colitis (Shoulder region)
0.287 0.712 0.000
M09.20 Juvenile arthritis in ulcerative colitis (Multiple sites)
0.287 0.712 0.000
M09.89 Juvenile arthritis in other diseases classified elsewhere (Site unspecified)
0.287 0.712 0.000
M09.88 Juvenile arthritis in other diseases classified elsewhere (Other)
0.287 0.712 0.000
M09.87 Juvenile arthritis in other diseases classified elsewhere (Ankle and foot)
0.287 0.712 0.000
M09.86 Juvenile arthritis in other diseases classified elsewhere (Lower leg)
0.287 0.712 0.000
M09.85 Juvenile arthritis in other diseases classified elsewhere (Pelvic region and thigh)
0.287 0.712 0.000
M09.84 Juvenile arthritis in other diseases classified elsewhere (Hand)
0.287 0.712 0.000
M09.83 Juvenile arthritis in other diseases classified elsewhere (Forearm)
0.287 0.712 0.000
M09.82 Juvenile arthritis in other diseases classified elsewhere (Upper arm)
0.287 0.712 0.000
M09.81 Juvenile arthritis in other diseases classified elsewhere (Shoulder region)
0.287 0.712 0.000
M09.80 Juvenile arthritis in other diseases classified elsewhere (Multiple sites)
0.287 0.712 0.000
M12.09 Chronic postrheumatic arthropathy [Jaccoud] (Site unspecified)
0.287 0.712 0.000
M12.08 Chronic postrheumatic arthropathy [Jaccoud] (Other)
0.287 0.712 0.000
M12.07 Chronic postrheumatic arthropathy [Jaccoud] (Ankle and foot)
0.287 0.712 0.000
M12.06 Chronic postrheumatic arthropathy [Jaccoud] (Lower leg)
0.287 0.712 0.000
M12.05 Chronic postrheumatic arthropathy [Jaccoud] (Pelvic region and thigh)
0.287 0.712 0.000
M12.04 Chronic postrheumatic arthropathy [Jaccoud] (Hand)
0.287 0.712 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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