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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28438860
log Bayes Factor = 9.95889
Chromosome 15   position 38,858,062  (GRCh37) Explore rs28438860 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.999 0.001 0.000
E10 Insulin-dependent diabetes mellitus
0.989 0.011 0.000
E05.9 Thyrotoxicosis, unspecified
0.988 0.012 0.000
E20-E35 Disorders of other endocrine glands
0.974 0.026 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.969 0.031 0.000
E50-E64 Other nutritional deficiencies
0.966 0.034 0.000
E10.9 Without complications
0.965 0.035 0.000
E14 Unspecified diabetes mellitus
0.926 0.074 0.000
E29 Testicular dysfunction
0.924 0.076 0.000
E53 Deficiency of other B group vitamins
0.916 0.084 0.000
E27 Other disorders of adrenal gland
0.908 0.092 0.000
E11 Non-insulin-dependent diabetes mellitus
0.902 0.098 0.000
E14.3 With ophthalmic complications
0.897 0.103 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.897 0.103 0.000
E10.0 With coma
0.893 0.107 0.000
M86-M90 Other osteopathies
0.892 0.108 0.000
E53.8 Deficiency of other specified B group vitamins
0.891 0.109 0.000
E29.1 Testicular hypofunction
0.888 0.112 0.000
E61 Deficiency of other nutrient elements
0.885 0.115 0.000
E22 Hyperfunction of pituitary gland
0.882 0.118 0.000
M65-M68 Disorders of synovium and tendon
0.875 0.125 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.873 0.127 0.000
M65 Synovitis and tenosynovitis
0.869 0.131 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.862 0.138 0.000
M87 Osteonecrosis
0.861 0.139 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.858 0.142 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.841 0.159 0.000
M89 Other disorders of bone
0.835 0.165 0.000
E03.8 Other specified hypothyroidism
0.835 0.165 0.000
E11.1 With ketoacidosis
0.834 0.166 0.000
E61.1 Iron deficiency
0.825 0.175 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.821 0.179 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.814 0.186 0.000
M40-M43 Deforming dorsopathies
0.812 0.188 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.810 0.190 0.000
E10.3 With ophthalmic complications
0.805 0.195 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.800 0.200 0.000
M87.9 Osteonecrosis, unspecified
0.799 0.201 0.000
E11.3 With ophthalmic complications
0.795 0.205 0.000
E10.7 With multiple complications
0.791 0.209 0.000
M05-M14 Inflammatory polyarthropathies
0.787 0.213 0.000
M15-M19 Arthrosis
0.785 0.215 0.000
M89.8 Other specified disorders of bone
0.782 0.218 0.000
M43 Other deforming dorsopathies
0.782 0.218 0.000
E05.8 Other thyrotoxicosis
0.782 0.218 0.000
M86 Osteomyelitis
0.781 0.219 0.000
E06 Thyroiditis
0.781 0.219 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.771 0.229 0.000
# Top node
0.771 0.229 0.000
Chapter VIII Diseases of the ear and mastoid process
0.768 0.232 0.000
E13 Other specified diabetes mellitus
0.767 0.233 0.000
E21.3 Hyperparathyroidism, unspecified
0.767 0.233 0.000
E11.9 Without complications
0.756 0.244 0.000
E10.6 With other specified complications
0.756 0.244 0.000
M07 Psoriatic and enteropathic arthropathies
0.754 0.246 0.000
E03.1 Congenital hypothyroidism without goitre
0.750 0.250 0.000
E14.6 With other specified complications
0.749 0.251 0.000
H65-H75 Diseases of middle ear and mastoid
0.749 0.251 0.000
H90-H95 Other disorders of ear
0.738 0.262 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.738 0.262 0.000
E10.8 With unspecified complications
0.737 0.263 0.000
M18 Arthrosis of first carpometacarpal joint
0.737 0.263 0.000
H92 Otalgia and effusion of ear
0.736 0.264 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.736 0.264 0.000
E27.1 Primary adrenocortical insufficiency
0.734 0.266 0.000
M00-M03 Infectious arthropathies
0.731 0.269 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.731 0.269 0.000
M07.3 Other psoriatic arthropathies
0.731 0.269 0.000
M60-M63 Disorders of muscles
0.727 0.273 0.000
M43.1 Spondylolisthesis
0.725 0.275 0.000
H92.0 Otalgia
0.723 0.277 0.000
M87.2 Osteonecrosis due to previous trauma
0.723 0.277 0.000
E65-E68 Obesity and other hyperalimentation
0.719 0.281 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
E05.5 Thyroid crisis or storm
0.716 0.284 0.000
E05.4 Thyrotoxicosis factitia
0.716 0.284 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.716 0.284 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.716 0.284 0.000
E11.8 With unspecified complications
0.715 0.285 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.712 0.288 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.711 0.289 0.000
E10.5 With peripheral circulatory complications
0.711 0.289 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.711 0.289 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.709 0.291 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.706 0.294 0.000
E11.4 With neurological complications
0.705 0.295 0.000
M87.8 Other osteonecrosis
0.704 0.296 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.703 0.297 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.702 0.298 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.701 0.299 0.000
E21.4 Other specified disorders of parathyroid gland
0.701 0.299 0.000
E20 Hypoparathyroidism
0.701 0.299 0.000
E58 Dietary calcium deficiency
0.699 0.301 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.698 0.302 0.000
E32 Diseases of thymus
0.698 0.302 0.000
E31 Polyglandular dysfunction
0.698 0.302 0.000
E30 Disorders of puberty, not elsewhere classified
0.698 0.302 0.000
E25 Adrenogenital disorders
0.698 0.302 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.696 0.304 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.693 0.307 0.000
E63 Other nutritional deficiencies
0.693 0.307 0.000
E56 Other vitamin deficiencies
0.693 0.307 0.000
E51 Thiamine deficiency
0.693 0.307 0.000
E50 Vitamin A deficiency
0.693 0.307 0.000
E60 Dietary zinc deficiency
0.693 0.307 0.000
E59 Dietary selenium deficiency
0.693 0.307 0.000
E54 Ascorbic acid deficiency
0.693 0.307 0.000
E52 Niacin deficiency [pellagra]
0.693 0.307 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.689 0.311 0.000
H92.1 Otorrhoea
0.687 0.313 0.000
E14.4 With neurological complications
0.685 0.314 0.000
M86.6 Other chronic osteomyelitis
0.683 0.317 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.680 0.320 0.000
H74 Other disorders of middle ear and mastoid
0.677 0.323 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.675 0.325 0.000
Chapter XX External causes of morbidity and mortality
0.673 0.327 0.000
M89.83 Other specified disorders of bone (Forearm)
0.670 0.330 0.000
M45-M49 Spondylopathies
0.668 0.332 0.000
E14.8 With unspecified complications
0.667 0.333 0.000
M89.3 Hypertrophy of bone
0.664 0.336 0.000
E14.7 With multiple complications
0.664 0.336 0.000
E14.0 With coma
0.664 0.336 0.000
E29.9 Testicular dysfunction, unspecified
0.662 0.338 0.000
E29.8 Other testicular dysfunction
0.662 0.338 0.000
E29.0 Testicular hyperfunction
0.662 0.338 0.000
M12 Other specific arthropathies
0.662 0.338 0.000
E27.8 Other specified disorders of adrenal gland
0.662 0.338 0.000
E14.5 With peripheral circulatory complications
0.660 0.340 0.000
M43.0 Spondylolysis
0.660 0.340 0.000
E53.1 Pyridoxine deficiency
0.657 0.343 0.000
E53.0 Riboflavin deficiency
0.657 0.343 0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)
0.657 0.343 0.000
Y86 Sequelae of other accidents
0.657 0.343 0.000
Y85 Sequelae of transport accidents
0.656 0.344 0.000
H71 Cholesteatoma of middle ear
0.655 0.345 0.000
E04 Other non-toxic goitre
0.655 0.345 0.000
M89.81 Other specified disorders of bone (Shoulder region)
0.654 0.346 0.000
E22.0 Acromegaly and pituitary gigantism
0.652 0.347 0.000
M19 Other arthrosis
0.652 0.348 0.000
M87.96 Osteonecrosis, unspecified (Lower leg)
0.652 0.348 0.000
E27.5 Adrenomedullary hyperfunction
0.651 0.349 0.000
E27.0 Other adrenocortical overactivity
0.651 0.349 0.000
Q00-Q07 Congenital malformations of the nervous system
0.650 0.350 0.000
E11.7 With multiple complications
0.647 0.353 0.000
E65 Localised adiposity
0.646 0.354 0.000
E34 Other endocrine disorders
0.644 0.356 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.644 0.356 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.644 0.356 0.000
M48 Other spondylopathies
0.641 0.359 0.000
E13.3 With ophthalmic complications
0.641 0.359 0.000
E61.2 Magnesium deficiency
0.641 0.359 0.000
H73 Other disorders of tympanic membrane
0.639 0.361 0.000
M06 Other rheumatoid arthritis
0.637 0.363 0.000
E28 Ovarian dysfunction
0.637 0.363 0.000
M90 Osteopathies in diseases classified elsewhere
0.637 0.363 0.000
E61.9 Deficiency of nutrient element, unspecified
0.634 0.365 0.000
E61.8 Deficiency of other specified nutrient elements
0.634 0.365 0.000
E61.7 Deficiency of multiple nutrient elements
0.634 0.365 0.000
E61.6 Vanadium deficiency
0.634 0.365 0.000
E61.5 Molybdenum deficiency
0.634 0.365 0.000
E61.4 Chromium deficiency
0.634 0.365 0.000
E61.3 Manganese deficiency
0.634 0.365 0.000
E61.0 Copper deficiency
0.634 0.365 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.633 0.367 0.000
E22.8 Other hyperfunction of pituitary gland
0.633 0.367 0.000
M02 Reactive arthropathies
0.632 0.368 0.000
E14.2 Withrenal complications
0.632 0.368 0.000
M65.1 Other infective (teno)synovitis
0.631 0.369 0.000
H70 Mastoiditis and related conditions
0.630 0.370 0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)
0.629 0.371 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.627 0.373 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.627 0.373 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.626 0.374 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.626 0.374 0.000
M43.2 Other fusion of spine
0.626 0.374 0.000
M89.89 Other specified disorders of bone (Site unspecified)
0.626 0.374 0.000
E14.1 With ketoacidosis
0.624 0.376 0.000
E10.4 With neurological complications
0.623 0.377 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.623 0.377 0.000
M87.98 Osteonecrosis, unspecified (Other)
0.623 0.377 0.000
M65.2 Calcific tendinitis
0.623 0.377 0.000
M65.0 Abscess of tendon sheath
0.623 0.377 0.000
M86.8 Other osteomyelitis
0.619 0.380 0.000
M15 Polyarthrosis
0.619 0.381 0.000
E10.2 With renal complications
0.618 0.381 0.000
M89.5 Osteolysis
0.618 0.381 0.000
E21.2 Other hyperparathyroidism
0.618 0.382 0.000
M20-M25 Other joint disorders
0.618 0.382 0.000
M87.3 Other secondary osteonecrosis
0.617 0.383 0.000
M87.1 Osteonecrosis due to drugs
0.617 0.383 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.617 0.383 0.000
Q23 Congenital malformations of aortic and mitral valves
0.615 0.385 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.615 0.385 0.000
Q24 Other congenital malformations of heart
0.612 0.388 0.000
L03 Cellulitis
0.611 0.389 0.000
H74.0 Tympanosclerosis
0.611 0.389 0.000
E27.9 Disorder of adrenal gland, unspecified
0.610 0.390 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.610 0.390 0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)
0.609 0.391 0.000
E27.2 Addisonian crisis
0.609 0.391 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.607 0.393 0.000
M80-M85 Disorders of bone density and structure
0.606 0.394 0.000
E04.9 Non-toxic goitre, unspecified
0.606 0.394 0.000
M88 Paget's disease of bone [osteitis deformans]
0.605 0.395 0.000
Q25 Congenital malformations of great arteries
0.603 0.397 0.000
E06.9 Thyroiditis, unspecified
0.603 0.397 0.000
L03.9 Cellulitis, unspecified
0.603 0.397 0.000
Y85.0 Sequelae of motor-vehicle accident
0.603 0.397 0.000
M62 Other disorders of muscle
0.602 0.398 0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)
0.602 0.398 0.000
M22 Disorders of patella
0.602 0.398 0.000
E26 Hyperaldosteronism
0.599 0.401 0.000
M89.6 Osteopathy after poliomyelitis
0.599 0.401 0.000
M89.2 Other disorders of bone development and growth
0.599 0.401 0.000
M89.1 Epiphyseal arrest
0.599 0.401 0.000
M43.02 Spondylolysis (Cervical region)
0.599 0.401 0.000
D80-D89 Certain disorders involving the immune mechanism
0.598 0.401 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.597 0.402 0.000
Q27 Other congenital malformations of peripheral vascular system
0.597 0.403 0.000
M89.84 Other specified disorders of bone (Hand)
0.593 0.407 0.000
H80-H83 Diseases of inner ear
0.593 0.407 0.000
E22.1 Hyperprolactinaemia
0.593 0.407 0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)
0.592 0.408 0.000
L40-L45 Papulosquamous disorders
0.590 0.410 0.000
D86 Sarcoidosis
0.589 0.411 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.587 0.413 0.000
E06.3 Autoimmune thyroiditis
0.587 0.413 0.000
Q05 Spina bifida
0.586 0.414 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.585 0.415 0.000
M12.3 Palindromic rheumatism
0.584 0.416 0.000
M42 Spinal osteochondrosis
0.582 0.418 0.000
L40 Psoriasis
0.580 0.420 0.000
M66 Spontaneous rupture of synovium and tendon
0.580 0.420 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.577 0.423 0.000
H73.8 Other specified disorders of tympanic membrane
0.577 0.423 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.577 0.423 0.000
W50-W64 Exposure to animate mechanical forces
0.576 0.424 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.574 0.426 0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)
0.573 0.427 0.000
M87.94 Osteonecrosis, unspecified (Hand)
0.573 0.427 0.000
M87.93 Osteonecrosis, unspecified (Forearm)
0.573 0.427 0.000
M87.92 Osteonecrosis, unspecified (Upper arm)
0.573 0.427 0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)
0.573 0.427 0.000
Chapter XXII Codes for special purposes
0.573 0.427 0.000
E11.0 With coma
0.570 0.430 0.000
E11.6 With other specified complications
0.570 0.430 0.000
L40.5 Arthropathic psoriasis
0.570 0.430 0.000
M31 Other necrotising vasculopathies
0.569 0.431 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.568 0.432 0.000
M91-M94 Chondropathies
0.568 0.432 0.000
M89.88 Other specified disorders of bone (Other)
0.567 0.433 0.000
M86.66 Other chronic osteomyelitis (Lower leg)
0.567 0.433 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.567 0.433 0.000
M22.4 Chondromalacia patellae
0.566 0.434 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.565 0.434 0.000
M43.6 Torticollis
0.565 0.435 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.565 0.435 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.564 0.436 0.000
M08 Juvenile arthritis
0.564 0.436 0.000
E07 Other disorders of thyroid
0.563 0.437 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.562 0.438 0.000
M89.82 Other specified disorders of bone (Upper arm)
0.561 0.439 0.000
M89.80 Other specified disorders of bone (Multiple sites)
0.561 0.439 0.000
E10.1 With ketoacidosis
0.561 0.439 0.000
M43.9 Deforming dorsopathy, unspecified
0.561 0.439 0.000
M43.8 Other specified deforming dorsopathies
0.561 0.439 0.000
M43.5 Other recurrent vertebral subluxation
0.561 0.439 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.561 0.439 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.561 0.439 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.560 0.440 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.560 0.440 0.000
M86.3 Chronic multifocal osteomyelitis
0.560 0.440 0.000
M86.2 Subacute osteomyelitis
0.560 0.440 0.000
M86.1 Other acute osteomyelitis
0.560 0.440 0.000
M86.0 Acute haematogenous osteomyelitis
0.560 0.440 0.000
E06.5 Other chronic thyroiditis
0.560 0.440 0.000
E06.4 Drug-induced thyroiditis
0.560 0.440 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.560 0.440 0.000
E06.1 Subacute thyroiditis
0.560 0.440 0.000
E06.0 Acute thyroiditis
0.560 0.440 0.000
M06.4 Inflammatory polyarthropathy
0.559 0.441 0.000
H74.4 Polyp of middle ear
0.556 0.444 0.000
M99 Biomechanical lesions, not elsewhere classified
0.555 0.445 0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)
0.554 0.445 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.553 0.447 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.553 0.447 0.000
M96.5 Postradiation scoliosis
0.553 0.447 0.000
M96.4 Postsurgical lordosis
0.553 0.447 0.000
M96.3 Postlaminectomy kyphosis
0.553 0.447 0.000
M96.2 Postradiation kyphosis
0.553 0.447 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.552 0.447 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.552 0.447 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.551 0.449 0.000
E13.8 With unspecified complications
0.550 0.450 0.000
E13.7 With multiple complications
0.550 0.450 0.000
E13.6 With other specified complications
0.550 0.450 0.000
E13.5 With peripheral circulatory complications
0.550 0.450 0.000
E13.4 With neurological complications
0.550 0.450 0.000
E13.2 With renal complications
0.550 0.450 0.000
E13.1 With ketoacidosis
0.550 0.450 0.000
E13.0 With coma
0.550 0.450 0.000
M40 Kyphosis and lordosis
0.550 0.450 0.000
E53.9 Vitamin B deficiency, unspecified
0.548 0.451 0.000
Q24.5 Malformation of coronary vessels
0.547 0.453 0.000
L03.1 Cellulitis of other parts of limb
0.545 0.455 0.000
M02.9 Reactive arthopathy, unspecified
0.541 0.459 0.000
M07.6 Other enteropathic arthropathies
0.541 0.459 0.000
M07.5 Arthropathy in ulcerative colitis
0.541 0.459 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.541 0.459 0.000
M07.2 Psoriatic spondylitis
0.541 0.459 0.000
M07.1 Arthritis mutilans
0.541 0.459 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.541 0.459 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.541 0.459 0.000
H65 Nonsuppurative otitis media
0.540 0.460 0.000
V40-V49 Car occupant injured in transport accident
0.540 0.460 0.000
Y88 Sequelae of surgical and medical care as external cause
0.540 0.460 0.000
M06.9 Rheumatoid arthritis, unspecified
0.539 0.461 0.000
M86.9 Osteomyelitis, unspecified
0.538 0.462 0.000
E40-E46 Malnutrition
0.537 0.462 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.537 0.463 0.000
H68 Eustachian salpingitis and obstruction
0.537 0.463 0.000
H67 Otitis media in diseases classified elsewhere
0.537 0.463 0.000
M89.37 Hypertrophy of bone (Ankle and foot)
0.536 0.463 0.000
X20-X29 Contact with venomous animals and plants
0.535 0.465 0.000
M86.69 Other chronic osteomyelitis (Site unspecified)
0.535 0.465 0.000
M89.0 Algoneurodystrophy
0.534 0.466 0.000
M19.9 Arthrosis, unspecified
0.532 0.468 0.000
M19.2 Other secondary arthrosis
0.531 0.469 0.000
M48.0 Spinal stenosis
0.530 0.470 0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.530 0.470 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.529 0.471 0.000
Y00-Y09 Assault
0.529 0.471 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.528 0.472 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.528 0.472 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.528 0.472 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.528 0.472 0.000
E34.9 Endocrine disorder, unspecified
0.528 0.472 0.000
H92.2 Otorrhagia
0.528 0.472 0.000
Q35-Q37 Cleft lip and cleft palate
0.528 0.472 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.528 0.472 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.527 0.473 0.000
M60 Myositis
0.527 0.473 0.000
H69 Other disorders of Eustachian tube
0.526 0.474 0.000
Q25.1 Coarctation of aorta
0.525 0.474 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.525 0.475 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.525 0.475 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.524 0.476 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.524 0.476 0.000
M07.38 Other psoriatic arthropathies (Other)
0.524 0.476 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.524 0.476 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.524 0.476 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.524 0.476 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.524 0.476 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.524 0.476 0.000
M49 Spondylopathies in diseases classified elsewhere
0.524 0.476 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.523 0.477 0.000
W55 Bitten or struck by other mammals
0.523 0.477 0.000
Q23.1 Congenital insufficiency of aortic valve
0.523 0.477 0.000
M31.3 Wegener's granulomatosis
0.523 0.477 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.521 0.479 0.000
M61 Calcification and ossification of muscle
0.521 0.479 0.000
E28.3 Primary ovarian failure
0.521 0.479 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.520 0.480 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.520 0.480 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.520 0.480 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.520 0.480 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.520 0.480 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.520 0.480 0.000
M16 Coxarthrosis [arthrosis of hip]
0.518 0.482 0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)
0.518 0.482 0.000
M87.28 Osteonecrosis due to previous trauma (Other)
0.518 0.482 0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)
0.518 0.482 0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)
0.518 0.482 0.000
M87.24 Osteonecrosis due to previous trauma (Hand)
0.518 0.482 0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)
0.518 0.482 0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)
0.518 0.482 0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)
0.518 0.482 0.000
M84 Disorders of continuity of bone
0.518 0.482 0.000
Y10-Y34 Event of undetermined intent
0.517 0.483 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.517 0.483 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.516 0.484 0.000
E67 Other hyperalimentation
0.516 0.484 0.000
E68 Sequelae of hyperalimentation
0.516 0.484 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.515 0.485 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
M05 Seropositive rheumatoid arthritis
0.514 0.486 0.000
D86.0 Sarcoidosis of lung
0.514 0.486 0.000
M43.27 Other fusion of spine (Lumbosacral region)
0.514 0.486 0.000
E12.9 Without complications
0.513 0.486 0.000
E12.8 With unspecified complications
0.513 0.486 0.000
E12.7 With multiple complications
0.513 0.486 0.000
E12.6 With other specified complications
0.513 0.486 0.000
E12.5 With peripheral circulatory complications
0.513 0.486 0.000
E12.4 With neurological complications
0.513 0.486 0.000
E12.3 With ophthalmic complications
0.513 0.486 0.000
E12.2 With renal complications
0.513 0.486 0.000
E12.1 With ketoacidosis
0.513 0.486 0.000
E12.0 With coma
0.513 0.486 0.000
E55 Vitamin D deficiency
0.512 0.488 0.000
M14 Arthropathies in other diseases classified elsewhere
0.511 0.489 0.000
M43.12 Spondylolisthesis (Cervical region)
0.510 0.489 0.000
Q26 Congenital malformations of great veins
0.510 0.490 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.510 0.490 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.509 0.491 0.000
M30 Polyarteritis nodosa and related conditions
0.509 0.491 0.000
X30-X39 Exposure to forces of nature
0.508 0.492 0.000
H72 Perforation of tympanic membrane
0.508 0.492 0.000
H93 Other disorders of ear, not elsewhere classified
0.506 0.494 0.000
E20.9 Hypoparathyroidism, unspecified
0.505 0.494 0.000
M87.89 Other osteonecrosis (Site unspecified)
0.505 0.495 0.000
M87.88 Other osteonecrosis (Other)
0.505 0.495 0.000
M87.87 Other osteonecrosis (Ankle and foot)
0.505 0.495 0.000
M87.86 Other osteonecrosis (Lower leg)
0.505 0.495 0.000
M87.84 Other osteonecrosis (Hand)
0.505 0.495 0.000
M87.83 Other osteonecrosis (Forearm)
0.505 0.495 0.000
M87.82 Other osteonecrosis (Upper arm)
0.505 0.495 0.000
M87.81 Other osteonecrosis (Shoulder region)
0.505 0.495 0.000
M87.80 Other osteonecrosis (Multiple sites)
0.505 0.495 0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)
0.504 0.496 0.000
M89.48 Other hypertrophic osteoarthropathy (Other)
0.504 0.496 0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)
0.504 0.496 0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)
0.504 0.496 0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)
0.504 0.496 0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)
0.504 0.496 0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)
0.504 0.496 0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)
0.504 0.496 0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)
0.504 0.496 0.000
D86.1 Sarcoidosis of lymph nodes
0.503 0.497 0.000
L10-L14 Bullous disorders
0.503 0.497 0.000
E20.8 Other hypoparathyroidism
0.503 0.497 0.000
E20.1 Pseudohypoparathyroidism
0.503 0.497 0.000
E20.0 Idiopathic hypoparathyroidism
0.503 0.497 0.000
D86.8 Sarcoidosis of other and combined sites
0.502 0.498 0.000
M22.3 Other derangements of patella
0.501 0.499 0.000
E25.9 Adrenogenital disorder, unspecified
0.500 0.499 0.000
E25.8 Other adrenogenital disorders
0.500 0.499 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.500 0.499 0.000
E30.9 Disorder of puberty, unspecified
0.500 0.499 0.000
E30.8 Other disorders of puberty
0.500 0.499 0.000
E30.1 Precocious puberty
0.500 0.499 0.000
E30.0 Delayed puberty
0.500 0.499 0.000
E31.9 Polyglandular dysfunction, unspecified
0.500 0.499 0.000
E31.8 Other polyglandular dysfunction
0.500 0.499 0.000
E31.1 Polyglandular hyperfunction
0.500 0.499 0.000
E31.0 Autoimmune polyglandular failure
0.500 0.499 0.000
E32.9 Disease of thymus, unspecified
0.500 0.499 0.000
E32.8 Other diseases of thymus
0.500 0.499 0.000
E32.1 Abscess of thymus
0.500 0.499 0.000
E32.0 Persistent hyperplasia of thymus
0.500 0.499 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.500 0.499 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.500 0.499 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.500 0.499 0.000
M31.1 Thrombotic microangiopathy
0.500 0.500 0.000
M62.8 Other specified disorders of muscle
0.499 0.501 0.000
Q05.9 Spina bifida, unspecified
0.498 0.501 0.000
W55.0 Home
0.498 0.502 0.000
M22.2 Patellofemoral disorders
0.498 0.502 0.000
X00-X09 Exposure to smoke, fire and flames
0.498 0.502 0.000
D50-D53 Nutritional anaemias
0.498 0.502 0.000
V10-V19 Pedal cyclist injured in transport accident
0.498 0.502 0.000
E50.9 Vitamin A deficiency, unspecified
0.497 0.503 0.000
E50.8 Other manifestations of vitamin A deficiency
0.497 0.503 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.497 0.503 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.497 0.503 0.000
E50.5 Vitamin A deficiency with night blindness
0.497 0.503 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.497 0.503 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.497 0.503 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.497 0.503 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.497 0.503 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.497 0.503 0.000
E51.9 Thiamine deficiency, unspecified
0.497 0.503 0.000
E51.8 Other manifestations of thiamine deficiency
0.497 0.503 0.000
E51.2 Wernicke's encephalopathy
0.497 0.503 0.000
E51.1 Beriberi
0.497 0.503 0.000
E56.9 Vitamin deficiency, unspecified
0.497 0.503 0.000
E56.8 Deficiency of other vitamins
0.497 0.503 0.000
E56.1 Deficiency of vitamin K
0.497 0.503 0.000
E56.0 Deficiency of vitamin E
0.497 0.503 0.000
E63.9 Nutritional deficiency, unspecified
0.497 0.503 0.000
E63.8 Other specified nutritional deficiencies
0.497 0.503 0.000
E63.1 Imbalance of constituents of food intake
0.497 0.503 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.497 0.503 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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