TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs2844484
log Bayes Factor = 87.9182
Chromosome 6   position 31,536,224  (GRCh37) Explore rs2844484 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.001 0.999
E10.4 With neurological complications
0.000 0.002 0.998
I20.0 Unstable angina
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.005 0.995
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.005 0.995
E78.0 Pure hypercholesterolaemia
0.000 0.005 0.995
E05.9 Thyrotoxicosis, unspecified
0.000 0.005 0.995
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.005 0.995
E70-E90 Metabolic disorders
0.000 0.005 0.995
E16 Other disorders of pancreatic internal secretion
0.000 0.008 0.992
E14.3 With ophthalmic complications
0.000 0.008 0.992
E14.9 Without complications
0.000 0.010 0.990
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.011 0.989
E11.3 With ophthalmic complications
0.000 0.012 0.988
E16.2 Hypoglycaemia, unspecified
0.000 0.012 0.988
H36.0 Diabetic retinopathy
0.000 0.032 0.968
E10.2 With renal complications
0.000 0.046 0.954
I22 Subsequent myocardial infarction
0.000 0.050 0.950
M06.9 Rheumatoid arthritis, unspecified
0.000 0.058 0.942
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.065 0.935
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.080 0.920
I25.5 Ischaemic cardiomyopathy
0.000 0.081 0.919
E11.1 With ketoacidosis
0.000 0.085 0.915
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.096 0.904
I24 Other acute ischaemic heart diseases
0.000 0.100 0.900
E10.0 With coma
0.000 0.105 0.895
E06 Thyroiditis
0.000 0.107 0.893
E88 Other metabolic disorders
0.000 0.117 0.883
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.117 0.883
E13 Other specified diabetes mellitus
0.000 0.122 0.878
E10.5 With peripheral circulatory complications
0.000 0.127 0.873
E11.0 With coma
0.000 0.129 0.871
I21 Acute myocardial infarction
0.000 0.131 0.869
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.131 0.869
E10.8 With unspecified complications
0.000 0.136 0.864
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.140 0.860
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.142 0.858
I21.9 Acute myocardial infarction, unspecified
0.000 0.145 0.855
I25.2 Old myocardial infarction
0.000 0.159 0.841
E14.6 With other specified complications
0.000 0.159 0.841
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.163 0.837
E06.3 Autoimmune thyroiditis
0.000 0.165 0.835
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.166 0.834
E40-E46 Malnutrition
0.000 0.172 0.828
E14.8 With unspecified complications
0.000 0.179 0.821
I24.8 Other forms of acute ischaemic heart disease
0.000 0.184 0.816
E14.4 With neurological complications
0.000 0.186 0.814
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.188 0.812
E78.1 Pure hyperglyceridaemia
0.000 0.194 0.806
E89.0 Postprocedural hypothyroidism
0.000 0.201 0.799
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.208 0.792
E10.6 With other specified complications
0.000 0.211 0.789
E11.2 With renal complications
0.000 0.219 0.781
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.221 0.779
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.222 0.778
E78.2 Mixed hyperlipidaemia
0.000 0.226 0.774
E13.9 Without complications
0.000 0.227 0.773
E74 Other disorders of carbohydrate metabolism
0.000 0.229 0.770
E78.6 Lipoprotein deficiency
0.000 0.239 0.761
E78.4 Other hyperlipidaemia
0.000 0.245 0.755
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.245 0.755
E14.1 With ketoacidosis
0.000 0.246 0.754
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.248 0.752
E89.3 Postprocedural hypopituitarism
0.000 0.252 0.748
M06 Other rheumatoid arthritis
0.000 0.263 0.737
E16.1 Other hypoglycaemia
0.000 0.269 0.731
E88.2 Lipomatosis, not elsewhere classified
0.000 0.270 0.730
E79 Disorders of purine and pyrimidine metabolism
0.000 0.270 0.730
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.277 0.723
E14.5 With peripheral circulatory complications
0.000 0.281 0.719
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.286 0.714
E78.3 Hyperchylomicronaemia
0.000 0.287 0.713
E77 Disorders of glycoprotein metabolism
0.000 0.287 0.713
E76 Disorders of glycosaminoglycan metabolism
0.000 0.287 0.713
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.287 0.713
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.287 0.713
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.287 0.713
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.289 0.711
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.289 0.711
E16.4 Abnormal secretion of gastrin
0.000 0.289 0.711
E16.3 Increased secretion of glucagon
0.000 0.289 0.711
I23 Certain current complications following acute myocardial infarction
0.000 0.290 0.710
E14.2 Withrenal complications
0.000 0.292 0.708
I25.4 Coronary artery aneurysm
0.000 0.293 0.707
E84 Cystic fibrosis
0.000 0.294 0.706
E46 Unspecified protein-energy malnutrition
0.000 0.295 0.705
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.295 0.705
E73 Lactose intolerance
0.000 0.302 0.698
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.305 0.695
E70 Disorders of aromatic amino-acid metabolism
0.000 0.307 0.693
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.309 0.690
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.311 0.689
E11.6 With other specified complications
0.000 0.316 0.684
E06.5 Other chronic thyroiditis
0.000 0.324 0.676
E13.3 With ophthalmic complications
0.000 0.328 0.672
E88.3 Tumour lysis syndrome
0.000 0.328 0.671
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.329 0.670
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.332 0.668
M06.3 Rheumatoid nodule
0.000 0.334 0.666
I25.6 Silent myocardial ischaemia
0.000 0.335 0.665
E88.9 Metabolic disorder, unspecified
0.000 0.337 0.663
E89.4 Postprocedural ovarian failure
0.000 0.341 0.659
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.357 0.643
E72 Other disorders of amino-acid metabolism
0.000 0.357 0.643
E06.4 Drug-induced thyroiditis
0.000 0.359 0.641
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.359 0.641
E06.0 Acute thyroiditis
0.000 0.359 0.641
M06.0 Seronegative rheumatoid arthritis
0.000 0.365 0.635
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.367 0.633
E89.5 Postprocedural testicular hypofunction
0.000 0.367 0.633
E89.1 Postprocedural hypoinsulinaemia
0.000 0.367 0.633
E13.8 With unspecified complications
0.000 0.370 0.630
E13.7 With multiple complications
0.000 0.370 0.630
E13.6 With other specified complications
0.000 0.370 0.630
E13.5 With peripheral circulatory complications
0.000 0.370 0.630
E13.4 With neurological complications
0.000 0.370 0.630
E13.2 With renal complications
0.000 0.370 0.630
E13.1 With ketoacidosis
0.000 0.370 0.630
E13.0 With coma
0.000 0.370 0.630
E88.8 Other specified metabolic disorders
0.000 0.371 0.629
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.377 0.623
E83.1 Disorders of iron metabolism
0.622 0.378 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.383 0.617
E78.8 Other disorders of lipoprotein metabolism
0.000 0.384 0.616
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.390 0.610
E14.0 With coma
0.000 0.400 0.599
G35 Multiple sclerosis
0.596 0.404 0.000
E06.1 Subacute thyroiditis
0.000 0.405 0.595
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.406 0.594
E45 Retarded development following protein-energy malnutrition
0.000 0.406 0.594
E43 Unspecified severe protein-energy malnutrition
0.000 0.406 0.594
E42 Marasmic kwashiorkor
0.000 0.406 0.594
E41 Nutritional marasmus
0.000 0.406 0.594
E40 Kwashiorkor
0.000 0.406 0.594
I25.3 Aneurysm of heart
0.000 0.408 0.592
E20-E35 Disorders of other endocrine glands
0.000 0.409 0.591
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.409 0.591
I20.1 Angina pectoris with documented spasm
0.000 0.417 0.583
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.417 0.583
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.418 0.582
E03.1 Congenital hypothyroidism without goitre
0.000 0.422 0.578
I22.8 Subsequent myocardial infarction of other sites
0.000 0.422 0.577
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.424 0.576
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.426 0.573
E06.9 Thyroiditis, unspecified
0.000 0.431 0.569
E80.6 Other disorders of bilirubin metabolism
0.000 0.434 0.566
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.447 0.552
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.447 0.552
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.447 0.552
E74.2 Disorders of galactose metabolism
0.000 0.447 0.552
E74.1 Disorders of fructose metabolism
0.000 0.447 0.552
E74.0 Glycogen storage disease
0.000 0.447 0.552
G35-G37 Demyelinating diseases of the central nervous system
0.552 0.448 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.449 0.551
I23.8 Other current complications following acute myocardial infarction
0.000 0.452 0.548
G37 Other demyelinating diseases of central nervous system
0.546 0.454 0.000
I24.1 Dressler's syndrome
0.000 0.458 0.542
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.459 0.540
E05.8 Other thyrotoxicosis
0.000 0.460 0.540
E11.8 With unspecified complications
0.000 0.465 0.535
G37.9 Demyelinating disease of central nervous system, unspecified
0.534 0.466 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.468 0.532
H36 Retinal disorders in diseases classified elsewhere
0.000 0.468 0.532
E03.8 Other specified hypothyroidism
0.000 0.468 0.531
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.470 0.530
M06.8 Other specified rheumatoid arthritis
0.000 0.471 0.528
M06.2 Rheumatoid bursitis
0.000 0.471 0.528
M06.1 Adult-onset Still's disease
0.000 0.471 0.528
E07 Other disorders of thyroid
0.000 0.475 0.525
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.476 0.523
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.476 0.523
E79.1 Lesch-Nyhan syndrome
0.000 0.476 0.523
E23 Hypofunction and other disorders of pituitary gland
0.000 0.478 0.522
E11.5 With peripheral circulatory complications
0.000 0.481 0.519
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E71.3 Disorders of fatty-acid metabolism
0.000 0.489 0.511
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.489 0.511
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.489 0.511
E71.0 Maple-syrup-urine disease
0.000 0.489 0.511
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.489 0.511
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.489 0.511
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.489 0.511
E76.2 Other mucopolysaccharidoses
0.000 0.489 0.511
E76.1 Mucopolysaccharidosis, type II
0.000 0.489 0.511
E76.0 Mucopolysaccharidosis, type I
0.000 0.489 0.511
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.489 0.511
E77.8 Other disorders of glycoprotein metabolism
0.000 0.489 0.511
E77.1 Defects in glycoprotein degradation
0.000 0.489 0.511
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.489 0.511
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.491 0.509
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.491 0.509
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.491 0.509
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.491 0.509
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.491 0.509
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.491 0.509
E84.8 Cystic fibrosis with other manifestations
0.000 0.494 0.506
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.494 0.506
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.494 0.506
E50-E64 Other nutritional deficiencies
0.000 0.495 0.505
E73.8 Other lactose intolerance
0.000 0.499 0.500
E73.1 Secondary lactase deficiency
0.000 0.499 0.500
E73.0 Congenital lactase deficiency
0.000 0.499 0.500
E84.9 Cystic fibrosis, unspecified
0.000 0.501 0.499
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.503 0.497
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.503 0.497
E70.2 Disorders of tyrosine metabolism
0.000 0.503 0.497
E70.1 Other hyperphenylalaninaemias
0.000 0.503 0.497
E70.0 Classical phenylketonuria
0.000 0.503 0.497
K90 Intestinal malabsorption
0.000 0.504 0.496
E75.6 Lipid storage disorder, unspecified
0.000 0.505 0.495
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.505 0.495
E75.3 Sphingolipidosis, unspecified
0.000 0.505 0.495
E75.2 Other sphingolipidosis
0.000 0.505 0.495
E75.1 Other gangliosidosis
0.000 0.505 0.495
E75.0 GM2 gangliosidosis
0.000 0.505 0.495
E23.6 Other disorders of pituitary gland
0.000 0.505 0.495
E86 Volume depletion
0.000 0.507 0.493
E24 Cushing's syndrome
0.000 0.507 0.493
E73.9 Lactose intolerance, unspecified
0.000 0.515 0.485
E80.1 Porphyria cutanea tarda
0.000 0.515 0.485
E80.2 Other porphyria
0.000 0.517 0.482
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.519 0.481
E80.5 Crigler-Najjar syndrome
0.000 0.519 0.481
E80.3 Defects of catalase and peroxydase
0.000 0.519 0.481
E80.0 Hereditary erythropoietic porphyria
0.000 0.519 0.481
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.523 0.477
M06.38 Rheumatoid nodule (Other)
0.000 0.523 0.477
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.523 0.477
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.523 0.477
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.523 0.477
E70.3 Albinism
0.000 0.523 0.477
E75.5 Other lipid storage disorders
0.000 0.527 0.472
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.538 0.462
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.539 0.461
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.539 0.461
E72.5 Disorders of glycine metabolism
0.000 0.539 0.461
E72.4 Disorders of ornithine metabolism
0.000 0.539 0.461
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.539 0.461
E72.2 Disorders of urea cycle metabolism
0.000 0.539 0.461
E65-E68 Obesity and other hyperalimentation
0.000 0.543 0.457
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.545 0.455
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.545 0.455
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.545 0.455
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.545 0.455
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.545 0.455
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.546 0.454
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.547 0.453
E28 Ovarian dysfunction
0.000 0.547 0.452
G37.8 Other specified demyelinating diseases of central nervous system
0.452 0.548 0.000
E61 Deficiency of other nutrient elements
0.000 0.553 0.447
E22 Hyperfunction of pituitary gland
0.000 0.555 0.445
I21.4 Acute subendocardial myocardial infarction
0.000 0.559 0.441
E72.0 Disorders of amino-acid transport
0.000 0.567 0.433
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.427 0.572 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.574 0.426
E44.0 Moderate protein-energy malnutrition
0.000 0.574 0.426
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.574 0.425
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.576 0.424
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.576 0.424
E32 Diseases of thymus
0.000 0.576 0.424
E31 Polyglandular dysfunction
0.000 0.576 0.424
E30 Disorders of puberty, not elsewhere classified
0.000 0.576 0.424
E23.2 Diabetes insipidus
0.000 0.576 0.424
M06.33 Rheumatoid nodule (Forearm)
0.000 0.581 0.419
E61.1 Iron deficiency
0.000 0.586 0.414
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.591 0.408
M06.4 Inflammatory polyarthropathy
0.000 0.592 0.407
E24.0 Pituitary-dependent Cushing's disease
0.000 0.593 0.407
E21.3 Hyperparathyroidism, unspecified
0.000 0.595 0.405
E24.2 Drug-induced Cushing's syndrome
0.000 0.598 0.402
E26 Hyperaldosteronism
0.000 0.598 0.402
K90.9 Intestinal malabsorption, unspecified
0.000 0.605 0.395
G37.5 Concentric sclerosis [Balo]
0.391 0.609 0.000
G37.4 Subacute necrotising myelitis
0.391 0.609 0.000
G37.2 Central pontine myelinolysis
0.391 0.609 0.000
G37.1 Central demyelination of corpus callosum
0.391 0.609 0.000
G37.0 Diffuse sclerosis
0.391 0.609 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.616 0.384
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.617 0.383
G36 Other acute disseminated demyelination
0.382 0.618 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.618 0.382
E23.7 Disorder of pituitary gland, unspecified
0.000 0.620 0.380
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.621 0.379
M06.18 Adult-onset Still's disease (Other)
0.000 0.621 0.379
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.621 0.379
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.621 0.379
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.621 0.379
M06.14 Adult-onset Still's disease (Hand)
0.000 0.621 0.379
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.621 0.379
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.621 0.379
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.621 0.379
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.621 0.379
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.621 0.379
M06.28 Rheumatoid bursitis (Other)
0.000 0.621 0.379
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.621 0.379
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.621 0.379
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.621 0.379
M06.24 Rheumatoid bursitis (Hand)
0.000 0.621 0.379
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.621 0.379
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.621 0.379
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.621 0.379
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.621 0.379
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.621 0.379
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.621 0.379
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.621 0.379
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.621 0.379
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.621 0.379
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.621 0.379
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.621 0.379
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.621 0.379
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.621 0.379
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.621 0.379
E28.2 Polycystic ovarian syndrome
0.000 0.622 0.378
E85 Amyloidosis
0.001 0.622 0.378
E07.1 Dyshormogenetic goitre
0.000 0.623 0.377
E07.0 Hypersecretion of calcitonin
0.000 0.623 0.377
E25 Adrenogenital disorders
0.000 0.624 0.376
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.625 0.375
E23.1 Drug-induced hypopituitarism
0.000 0.625 0.375
E20 Hypoparathyroidism
0.000 0.630 0.370
E22.0 Acromegaly and pituitary gigantism
0.000 0.633 0.367
E07.8 Other specified disorders of thyroid
0.000 0.635 0.365
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.637 0.363
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.638 0.362
E63 Other nutritional deficiencies
0.000 0.638 0.362
E51 Thiamine deficiency
0.000 0.638 0.362
E50 Vitamin A deficiency
0.000 0.638 0.362
E60 Dietary zinc deficiency
0.000 0.638 0.362
E59 Dietary selenium deficiency
0.000 0.638 0.362
E52 Niacin deficiency [pellagra]
0.000 0.638 0.362
E56 Other vitamin deficiencies
0.000 0.643 0.357
K90.3 Pancreatic steatorrhoea
0.000 0.644 0.355
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.644 0.355
K90.1 Tropical sprue
0.000 0.644 0.355
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.646 0.354
E24.3 Ectopic ACTH syndrome
0.000 0.646 0.354
E24.1 Nelson's syndrome
0.000 0.646 0.354
E89.2 Postprocedural hypoparathyroidism
0.001 0.647 0.353
K90.8 Other intestinal malabsorption
0.000 0.650 0.350
E21.2 Other hyperparathyroidism
0.000 0.652 0.348
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.653 0.347
E24.8 Other Cushing's syndrome
0.000 0.653 0.347
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.661 0.339
E65 Localised adiposity
0.000 0.665 0.334
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.668 0.332
E58 Dietary calcium deficiency
0.000 0.670 0.330
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.671 0.329
E21.4 Other specified disorders of parathyroid gland
0.000 0.671 0.328
E67 Other hyperalimentation
0.000 0.672 0.328
E68 Sequelae of hyperalimentation
0.000 0.672 0.328
E24.9 Cushing's syndrome, unspecified
0.000 0.672 0.328
E28.9 Ovarian dysfunction, unspecified
0.000 0.675 0.324
E28.8 Other ovarian dysfunction
0.000 0.675 0.324
E28.1 Androgen excess
0.000 0.675 0.324
E28.0 Oestrogen excess
0.000 0.675 0.324
E83 Disorders of mineral metabolism
0.263 0.676 0.061
E61.9 Deficiency of nutrient element, unspecified
0.000 0.680 0.320
E61.8 Deficiency of other specified nutrient elements
0.000 0.680 0.320
E61.7 Deficiency of multiple nutrient elements
0.000 0.680 0.320
E61.6 Vanadium deficiency
0.000 0.680 0.320
E61.5 Molybdenum deficiency
0.000 0.680 0.320
E61.4 Chromium deficiency
0.000 0.680 0.320
E61.3 Manganese deficiency
0.000 0.680 0.320
E61.0 Copper deficiency
0.000 0.680 0.320
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.681 0.319
E22.8 Other hyperfunction of pituitary gland
0.000 0.681 0.319
E54 Ascorbic acid deficiency
0.000 0.691 0.309
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.691 0.309
E30.9 Disorder of puberty, unspecified
0.000 0.696 0.304
E30.8 Other disorders of puberty
0.000 0.696 0.304
E30.1 Precocious puberty
0.000 0.696 0.304
E30.0 Delayed puberty
0.000 0.696 0.304
E31.9 Polyglandular dysfunction, unspecified
0.000 0.696 0.304
E31.8 Other polyglandular dysfunction
0.000 0.696 0.304
E31.1 Polyglandular hyperfunction
0.000 0.696 0.304
E31.0 Autoimmune polyglandular failure
0.000 0.696 0.304
E32.9 Disease of thymus, unspecified
0.000 0.696 0.304
E32.8 Other diseases of thymus
0.000 0.696 0.304
E32.1 Abscess of thymus
0.000 0.696 0.304
E32.0 Persistent hyperplasia of thymus
0.000 0.696 0.304
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.696 0.304
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.696 0.304
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.696 0.304
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.697 0.303
E29 Testicular dysfunction
0.000 0.700 0.299
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.707 0.292
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.707 0.292
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.707 0.292
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.707 0.292
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.707 0.292
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.707 0.292
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.707 0.292
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.707 0.292
E26.9 Hyperaldosteronism, unspecified
0.000 0.712 0.288
E26.8 Other hyperaldosteronism
0.000 0.712 0.288
E26.1 Secondary hyperaldosteronism
0.000 0.712 0.288
E61.2 Magnesium deficiency
0.000 0.713 0.287
E28.3 Primary ovarian failure
0.000 0.719 0.281
E27 Other disorders of adrenal gland
0.000 0.721 0.279
G36.9 Acute disseminated demyelination, unspecified
0.274 0.726 0.000
G36.8 Other specified acute disseminated demyelination
0.274 0.726 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.274 0.726 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.729 0.271
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.729 0.271
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.729 0.271
E25.9 Adrenogenital disorder, unspecified
0.000 0.730 0.270
E25.8 Other adrenogenital disorders
0.000 0.730 0.270
E26.0 Primary hyperaldosteronism
0.000 0.734 0.266
E20.1 Pseudohypoparathyroidism
0.000 0.734 0.265
E20.0 Idiopathic hypoparathyroidism
0.000 0.734 0.265
E34 Other endocrine disorders
0.001 0.735 0.264
G36.0 Neuromyelitis optica [Devic]
0.260 0.740 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.740 0.260
E50.8 Other manifestations of vitamin A deficiency
0.000 0.740 0.260
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.740 0.260
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.740 0.260
E50.5 Vitamin A deficiency with night blindness
0.000 0.740 0.260
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.740 0.260
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.740 0.260
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.740 0.260
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.740 0.260
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.740 0.260
E51.9 Thiamine deficiency, unspecified
0.000 0.740 0.260
E51.8 Other manifestations of thiamine deficiency
0.000 0.740 0.260
E51.2 Wernicke's encephalopathy
0.000 0.740 0.260
E51.1 Beriberi
0.000 0.740 0.260
E63.9 Nutritional deficiency, unspecified
0.000 0.740 0.260
E63.8 Other specified nutritional deficiencies
0.000 0.740 0.260
E63.1 Imbalance of constituents of food intake
0.000 0.740 0.260
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.740 0.260
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.740 0.260
E64.8 Sequelae of other nutritional deficiencies
0.000 0.740 0.260
E64.3 Sequelae of rickets
0.000 0.740 0.260
E64.2 Sequelae of vitamin C deficiency
0.000 0.740 0.260
E64.1 Sequelae of vitamin A deficiency
0.000 0.740 0.260
E64.0 Sequelae of protein-energy malnutrition
0.000 0.740 0.260
E56.9 Vitamin deficiency, unspecified
0.000 0.744 0.256
E56.8 Deficiency of other vitamins
0.000 0.744 0.256
E56.0 Deficiency of vitamin E
0.000 0.744 0.256
E56.1 Deficiency of vitamin K
0.000 0.749 0.251
E55 Vitamin D deficiency
0.000 0.749 0.250
E20.9 Hypoparathyroidism, unspecified
0.000 0.754 0.246
E27.9 Disorder of adrenal gland, unspecified
0.000 0.754 0.245
E83.9 Disorder of mineral metabolism, unspecified
0.208 0.755 0.037
E85.4 Organ-limited amyloidosis
0.000 0.756 0.243
E80.4 Gilbert's syndrome
0.000 0.763 0.237
E20.8 Other hypoparathyroidism
0.000 0.764 0.236
E67.8 Other specified hyperalimentation
0.000 0.765 0.235
E67.3 Hypervitaminosis D
0.000 0.765 0.235
E67.2 Megavitamin-B6 syndrome
0.000 0.765 0.235

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2024 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.