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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2844496
log Bayes Factor = 7.14328
Chromosome 6   position 31,480,398  (GRCh37) Explore rs2844496 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.001 0.999
E10.9 Without complications
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.002 0.998
E10 Insulin-dependent diabetes mellitus
0.000 0.003 0.997
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.010 0.990
E10-E14 Diabetes mellitus
0.000 0.011 0.989
E10.3 With ophthalmic complications
0.000 0.024 0.976
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.038 0.962
E06 Thyroiditis
0.000 0.057 0.943
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.073 0.927
E06.3 Autoimmune thyroiditis
0.000 0.091 0.909
E10.1 With ketoacidosis
0.000 0.133 0.867
E05.9 Thyrotoxicosis, unspecified
0.000 0.171 0.829
E70-E90 Metabolic disorders
0.000 0.216 0.784
E40-E46 Malnutrition
0.000 0.236 0.764
E03.8 Other specified hypothyroidism
0.000 0.237 0.763
E86 Volume depletion
0.000 0.263 0.737
E65-E68 Obesity and other hyperalimentation
0.000 0.264 0.736
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.273 0.727
E20-E35 Disorders of other endocrine glands
0.000 0.284 0.716
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E03.1 Congenital hypothyroidism without goitre
0.000 0.284 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.285 0.715
E10.7 With multiple complications
0.000 0.285 0.715
E10.0 With coma
0.000 0.285 0.715
E12 Malnutrition-related diabetes mellitus
0.000 0.291 0.709
E10.5 With peripheral circulatory complications
0.000 0.291 0.709
E05.5 Thyroid crisis or storm
0.000 0.310 0.690
E05.4 Thyrotoxicosis factitia
0.000 0.310 0.690
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.310 0.690
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.310 0.690
E10.2 With renal complications
0.000 0.313 0.687
E80.4 Gilbert's syndrome
0.000 0.313 0.687
E10.8 With unspecified complications
0.000 0.318 0.682
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.319 0.681
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.321 0.679
E06.5 Other chronic thyroiditis
0.000 0.324 0.676
E06.4 Drug-induced thyroiditis
0.000 0.324 0.676
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.324 0.676
E06.1 Subacute thyroiditis
0.000 0.324 0.676
E06.0 Acute thyroiditis
0.000 0.324 0.676
E73 Lactose intolerance
0.000 0.349 0.651
E10.6 With other specified complications
0.000 0.352 0.648
E27 Other disorders of adrenal gland
0.000 0.353 0.647
E06.9 Thyroiditis, unspecified
0.000 0.366 0.634
E10.4 With neurological complications
0.000 0.372 0.628
E65 Localised adiposity
0.000 0.392 0.608
E46 Unspecified protein-energy malnutrition
0.000 0.398 0.602
E28 Ovarian dysfunction
0.000 0.403 0.597
E27.1 Primary adrenocortical insufficiency
0.000 0.405 0.595
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.421 0.579
E88 Other metabolic disorders
0.000 0.427 0.573
E05.8 Other thyrotoxicosis
0.000 0.434 0.566
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.435 0.565
E84 Cystic fibrosis
0.000 0.437 0.562
E79 Disorders of purine and pyrimidine metabolism
0.000 0.437 0.562
E77 Disorders of glycoprotein metabolism
0.000 0.437 0.562
E76 Disorders of glycosaminoglycan metabolism
0.000 0.437 0.562
E72 Other disorders of amino-acid metabolism
0.000 0.437 0.562
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.437 0.562
E70 Disorders of aromatic amino-acid metabolism
0.000 0.437 0.562
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.437 0.562
E73.9 Lactose intolerance, unspecified
0.000 0.445 0.555
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.452 0.548
E45 Retarded development following protein-energy malnutrition
0.000 0.452 0.548
E43 Unspecified severe protein-energy malnutrition
0.000 0.452 0.548
E42 Marasmic kwashiorkor
0.000 0.452 0.548
E41 Nutritional marasmus
0.000 0.452 0.548
E40 Kwashiorkor
0.000 0.452 0.548
E20 Hypoparathyroidism
0.000 0.460 0.540
E67 Other hyperalimentation
0.000 0.472 0.528
E68 Sequelae of hyperalimentation
0.000 0.472 0.528
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.478 0.522
E80.6 Other disorders of bilirubin metabolism
0.000 0.478 0.522
E80.5 Crigler-Najjar syndrome
0.000 0.478 0.522
E80.3 Defects of catalase and peroxydase
0.000 0.478 0.522
E80.2 Other porphyria
0.000 0.478 0.522
E80.1 Porphyria cutanea tarda
0.000 0.478 0.522
E80.0 Hereditary erythropoietic porphyria
0.000 0.478 0.522
E74 Other disorders of carbohydrate metabolism
0.000 0.479 0.521
E13 Other specified diabetes mellitus
0.001 0.482 0.518
E27.2 Addisonian crisis
0.000 0.482 0.517
E50-E64 Other nutritional deficiencies
0.000 0.484 0.516
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.485 0.515
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.486 0.513
E32 Diseases of thymus
0.000 0.486 0.513
E31 Polyglandular dysfunction
0.000 0.486 0.513
E30 Disorders of puberty, not elsewhere classified
0.000 0.486 0.513
E25 Adrenogenital disorders
0.000 0.486 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E28.2 Polycystic ovarian syndrome
0.000 0.487 0.513
E24 Cushing's syndrome
0.000 0.489 0.511
E89.0 Postprocedural hypothyroidism
0.000 0.489 0.511
E12.9 Without complications
0.000 0.491 0.509
E12.8 With unspecified complications
0.000 0.491 0.509
E12.7 With multiple complications
0.000 0.491 0.509
E12.6 With other specified complications
0.000 0.491 0.509
E12.5 With peripheral circulatory complications
0.000 0.491 0.509
E12.4 With neurological complications
0.000 0.491 0.509
E12.3 With ophthalmic complications
0.000 0.491 0.509
E12.2 With renal complications
0.000 0.491 0.509
E12.1 With ketoacidosis
0.000 0.491 0.509
E12.0 With coma
0.000 0.491 0.509
E26 Hyperaldosteronism
0.000 0.499 0.501
E07 Other disorders of thyroid
0.000 0.509 0.491
E27.8 Other specified disorders of adrenal gland
0.000 0.513 0.486
E27.9 Disorder of adrenal gland, unspecified
0.000 0.517 0.483
E73.8 Other lactose intolerance
0.000 0.533 0.467
E73.1 Secondary lactase deficiency
0.000 0.533 0.467
E73.0 Congenital lactase deficiency
0.000 0.533 0.467
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.533 0.467
E27.5 Adrenomedullary hyperfunction
0.000 0.536 0.464
E27.0 Other adrenocortical overactivity
0.000 0.536 0.464
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.546 0.454
E66 Obesity
0.000 0.559 0.441
E22 Hyperfunction of pituitary gland
0.000 0.567 0.433
E34 Other endocrine disorders
0.000 0.571 0.429
E28.9 Ovarian dysfunction, unspecified
0.000 0.572 0.428
E28.8 Other ovarian dysfunction
0.000 0.572 0.428
E28.1 Androgen excess
0.000 0.572 0.428
E28.0 Oestrogen excess
0.000 0.572 0.428
E29 Testicular dysfunction
0.000 0.572 0.428
E28.3 Primary ovarian failure
0.000 0.574 0.426
E14 Unspecified diabetes mellitus
0.000 0.578 0.422
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.580 0.420
E15 Nondiabetic hypoglycaemic coma
0.000 0.585 0.415
E20.9 Hypoparathyroidism, unspecified
0.000 0.585 0.415
E23 Hypofunction and other disorders of pituitary gland
0.000 0.586 0.414
E66.8 Other obesity
0.000 0.588 0.412
E88.9 Metabolic disorder, unspecified
0.000 0.589 0.411
E88.8 Other specified metabolic disorders
0.000 0.589 0.411
E88.3 Tumour lysis syndrome
0.000 0.589 0.411
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.589 0.411
E21.3 Hyperparathyroidism, unspecified
0.000 0.593 0.407
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.594 0.405
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.594 0.405
E89.5 Postprocedural testicular hypofunction
0.000 0.594 0.405
E89.4 Postprocedural ovarian failure
0.000 0.594 0.405
E89.1 Postprocedural hypoinsulinaemia
0.000 0.594 0.405
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.596 0.403
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.596 0.403
E70.3 Albinism
0.000 0.596 0.403
E70.2 Disorders of tyrosine metabolism
0.000 0.596 0.403
E70.1 Other hyperphenylalaninaemias
0.000 0.596 0.403
E70.0 Classical phenylketonuria
0.000 0.596 0.403
E71.3 Disorders of fatty-acid metabolism
0.000 0.596 0.403
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.596 0.403
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.596 0.403
E71.0 Maple-syrup-urine disease
0.000 0.596 0.403
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.596 0.403
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.596 0.403
E72.5 Disorders of glycine metabolism
0.000 0.596 0.403
E72.4 Disorders of ornithine metabolism
0.000 0.596 0.403
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.596 0.403
E72.2 Disorders of urea cycle metabolism
0.000 0.596 0.403
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.596 0.403
E72.0 Disorders of amino-acid transport
0.000 0.596 0.403
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.596 0.403
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.596 0.403
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.596 0.403
E76.2 Other mucopolysaccharidoses
0.000 0.596 0.403
E76.1 Mucopolysaccharidosis, type II
0.000 0.596 0.403
E76.0 Mucopolysaccharidosis, type I
0.000 0.596 0.403
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.596 0.403
E77.8 Other disorders of glycoprotein metabolism
0.000 0.596 0.403
E77.1 Defects in glycoprotein degradation
0.000 0.596 0.403
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.596 0.403
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.596 0.403
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.596 0.403
E79.1 Lesch-Nyhan syndrome
0.000 0.596 0.403
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.596 0.403
E84.9 Cystic fibrosis, unspecified
0.000 0.596 0.403
E84.8 Cystic fibrosis with other manifestations
0.000 0.596 0.403
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.596 0.403
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.596 0.403
E89.3 Postprocedural hypopituitarism
0.000 0.603 0.397
E85 Amyloidosis
0.000 0.603 0.396
E83 Disorders of mineral metabolism
0.000 0.605 0.395
E44.1 Mild protein-energy malnutrition
0.000 0.607 0.393
E44.0 Moderate protein-energy malnutrition
0.000 0.607 0.393
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.607 0.392
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.608 0.392
E20.8 Other hypoparathyroidism
0.000 0.612 0.387
E20.1 Pseudohypoparathyroidism
0.000 0.612 0.387
E20.0 Idiopathic hypoparathyroidism
0.000 0.612 0.387
E67.8 Other specified hyperalimentation
0.000 0.621 0.378
E67.3 Hypervitaminosis D
0.000 0.621 0.378
E67.2 Megavitamin-B6 syndrome
0.000 0.621 0.378
E67.1 Hypercarotenaemia
0.000 0.621 0.378
E67.0 Hypervitaminosis A
0.000 0.621 0.378
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.621 0.378
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.626 0.374
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.626 0.374
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.626 0.374
E74.2 Disorders of galactose metabolism
0.000 0.626 0.374
E74.1 Disorders of fructose metabolism
0.000 0.626 0.374
E74.0 Glycogen storage disease
0.000 0.626 0.374
E13.8 With unspecified complications
0.001 0.628 0.371
E13.7 With multiple complications
0.001 0.628 0.371
E13.6 With other specified complications
0.001 0.628 0.371
E13.5 With peripheral circulatory complications
0.001 0.628 0.371
E13.4 With neurological complications
0.001 0.628 0.371
E13.3 With ophthalmic complications
0.001 0.628 0.371
E13.2 With renal complications
0.001 0.628 0.371
E13.1 With ketoacidosis
0.001 0.628 0.371
E13.0 With coma
0.001 0.628 0.371
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.630 0.370
E63 Other nutritional deficiencies
0.000 0.630 0.370
E56 Other vitamin deficiencies
0.000 0.630 0.370
E51 Thiamine deficiency
0.000 0.630 0.370
E50 Vitamin A deficiency
0.000 0.630 0.370
E60 Dietary zinc deficiency
0.000 0.630 0.370
E59 Dietary selenium deficiency
0.000 0.630 0.370
E58 Dietary calcium deficiency
0.000 0.630 0.370
E54 Ascorbic acid deficiency
0.000 0.630 0.370
E52 Niacin deficiency [pellagra]
0.000 0.630 0.370
E75.6 Lipid storage disorder, unspecified
0.000 0.630 0.369
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.630 0.369
E75.3 Sphingolipidosis, unspecified
0.000 0.630 0.369
E75.2 Other sphingolipidosis
0.000 0.630 0.369
E75.1 Other gangliosidosis
0.000 0.630 0.369
E75.0 GM2 gangliosidosis
0.000 0.630 0.369
E25.9 Adrenogenital disorder, unspecified
0.000 0.632 0.368
E25.8 Other adrenogenital disorders
0.000 0.632 0.368
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.632 0.368
E30.9 Disorder of puberty, unspecified
0.000 0.632 0.368
E30.8 Other disorders of puberty
0.000 0.632 0.368
E30.1 Precocious puberty
0.000 0.632 0.368
E30.0 Delayed puberty
0.000 0.632 0.368
E31.9 Polyglandular dysfunction, unspecified
0.000 0.632 0.368
E31.8 Other polyglandular dysfunction
0.000 0.632 0.368
E31.1 Polyglandular hyperfunction
0.000 0.632 0.368
E31.0 Autoimmune polyglandular failure
0.000 0.632 0.368
E32.9 Disease of thymus, unspecified
0.000 0.632 0.368
E32.8 Other diseases of thymus
0.000 0.632 0.368
E32.1 Abscess of thymus
0.000 0.632 0.368
E32.0 Persistent hyperplasia of thymus
0.000 0.632 0.368
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.632 0.368
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.632 0.368
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.632 0.368
E24.8 Other Cushing's syndrome
0.000 0.633 0.367
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.633 0.367
E24.3 Ectopic ACTH syndrome
0.000 0.633 0.367
E24.2 Drug-induced Cushing's syndrome
0.000 0.633 0.367
E24.1 Nelson's syndrome
0.000 0.633 0.367
E24.0 Pituitary-dependent Cushing's disease
0.000 0.633 0.367
E88.2 Lipomatosis, not elsewhere classified
0.000 0.635 0.364
E53 Deficiency of other B group vitamins
0.000 0.635 0.365
E24.9 Cushing's syndrome, unspecified
0.000 0.635 0.364
E04 Other non-toxic goitre
0.000 0.636 0.364
E26.9 Hyperaldosteronism, unspecified
0.000 0.641 0.359
E26.8 Other hyperaldosteronism
0.000 0.641 0.359
E26.1 Secondary hyperaldosteronism
0.000 0.641 0.359
E07.1 Dyshormogenetic goitre
0.000 0.647 0.352
E07.0 Hypersecretion of calcitonin
0.000 0.647 0.352
E22.0 Acromegaly and pituitary gigantism
0.000 0.648 0.352
E83.3 Disorders of phosphorus metabolism
0.000 0.650 0.350
E07.8 Other specified disorders of thyroid
0.000 0.651 0.348
E26.0 Primary hyperaldosteronism
0.000 0.653 0.346
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.665 0.335
E21.4 Other specified disorders of parathyroid gland
0.000 0.665 0.335
E21.2 Other hyperparathyroidism
0.000 0.665 0.335
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.667 0.333
E87.7 Fluid overload
0.000 0.671 0.329
E61 Deficiency of other nutrient elements
0.000 0.675 0.325
E75.5 Other lipid storage disorders
0.000 0.677 0.322
E66.1 Drug-induced obesity
0.000 0.684 0.316
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.689 0.310
E22.8 Other hyperfunction of pituitary gland
0.000 0.689 0.310
E87.2 Acidosis
0.000 0.689 0.311
E34.5 Androgen resistance syndrome
0.000 0.692 0.308
E34.4 Constitutional tall stature
0.000 0.692 0.308
E34.3 Short stature, not elsewhere classified
0.000 0.692 0.308
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.692 0.308
E34.1 Other hypersecretion of intestinal hormones
0.000 0.692 0.308
E29.9 Testicular dysfunction, unspecified
0.000 0.693 0.307
E29.8 Other testicular dysfunction
0.000 0.693 0.307
E29.0 Testicular hyperfunction
0.000 0.693 0.307
E04.0 Non-toxic diffuse goitre
0.000 0.695 0.305
E14.8 With unspecified complications
0.000 0.697 0.303
E14.7 With multiple complications
0.000 0.697 0.303
E14.6 With other specified complications
0.000 0.697 0.303
E14.5 With peripheral circulatory complications
0.000 0.697 0.303
E14.4 With neurological complications
0.000 0.697 0.303
E14.0 With coma
0.000 0.697 0.303
E34.8 Other specified endocrine disorders
0.000 0.698 0.302
E23.7 Disorder of pituitary gland, unspecified
0.000 0.703 0.297
E23.6 Other disorders of pituitary gland
0.000 0.703 0.297
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.703 0.297
E23.1 Drug-induced hypopituitarism
0.000 0.703 0.297
E85.4 Organ-limited amyloidosis
0.000 0.703 0.297
E87.0 Hyperosmolality and hypernatraemia
0.000 0.704 0.296
E66.0 Obesity due to excess calories
0.000 0.706 0.293
E23.2 Diabetes insipidus
0.000 0.709 0.291
E14.3 With ophthalmic complications
0.000 0.715 0.285
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.715 0.284
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.715 0.284
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.715 0.284
E16 Other disorders of pancreatic internal secretion
0.000 0.716 0.284
E34.0 Carcinoid syndrome
0.000 0.716 0.284
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.716 0.284
E83.8 Other disorders of mineral metabolism
0.000 0.716 0.284
E83.2 Disorders of zinc metabolism
0.000 0.716 0.284
E83.0 Disorders of copper metabolism
0.000 0.716 0.284
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.717 0.283
E87.4 Mixed disorder of acid-base balance
0.000 0.719 0.281
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.720 0.280
E14.1 With ketoacidosis
0.000 0.721 0.279
E87.3 Alkalosis
0.000 0.733 0.267
E55 Vitamin D deficiency
0.000 0.733 0.266
E14.2 Withrenal complications
0.000 0.734 0.266
E50.9 Vitamin A deficiency, unspecified
0.000 0.734 0.265
E50.8 Other manifestations of vitamin A deficiency
0.000 0.734 0.265
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.734 0.265
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.734 0.265
E50.5 Vitamin A deficiency with night blindness
0.000 0.734 0.265
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.734 0.265
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.734 0.265
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.734 0.265
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.734 0.265
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.734 0.265
E51.9 Thiamine deficiency, unspecified
0.000 0.734 0.265
E51.8 Other manifestations of thiamine deficiency
0.000 0.734 0.265
E51.2 Wernicke's encephalopathy
0.000 0.734 0.265
E51.1 Beriberi
0.000 0.734 0.265
E56.9 Vitamin deficiency, unspecified
0.000 0.734 0.265
E56.8 Deficiency of other vitamins
0.000 0.734 0.265
E56.1 Deficiency of vitamin K
0.000 0.734 0.265
E56.0 Deficiency of vitamin E
0.000 0.734 0.265
E63.9 Nutritional deficiency, unspecified
0.000 0.734 0.265
E63.8 Other specified nutritional deficiencies
0.000 0.734 0.265
E63.1 Imbalance of constituents of food intake
0.000 0.734 0.265
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.734 0.265
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.734 0.265
E64.8 Sequelae of other nutritional deficiencies
0.000 0.734 0.265
E64.3 Sequelae of rickets
0.000 0.734 0.265
E64.2 Sequelae of vitamin C deficiency
0.000 0.734 0.265
E64.1 Sequelae of vitamin A deficiency
0.000 0.734 0.265
E64.0 Sequelae of protein-energy malnutrition
0.000 0.734 0.265
E34.9 Endocrine disorder, unspecified
0.000 0.734 0.265
E53.8 Deficiency of other specified B group vitamins
0.000 0.735 0.265
E83.4 Disorders of magnesium metabolism
0.000 0.736 0.264
E22.1 Hyperprolactinaemia
0.000 0.738 0.261
E53.1 Pyridoxine deficiency
0.000 0.738 0.261
E53.0 Riboflavin deficiency
0.000 0.738 0.261
E04.8 Other specified non-toxic goitre
0.000 0.739 0.261
E53.9 Vitamin B deficiency, unspecified
0.000 0.747 0.252
E85.9 Amyloidosis, unspecified
0.001 0.751 0.248
E85.8 Other amyloidosis
0.001 0.764 0.235
E61.9 Deficiency of nutrient element, unspecified
0.000 0.767 0.233
E61.8 Deficiency of other specified nutrient elements
0.000 0.767 0.233
E61.7 Deficiency of multiple nutrient elements
0.000 0.767 0.233
E61.6 Vanadium deficiency
0.000 0.767 0.233
E61.5 Molybdenum deficiency
0.000 0.767 0.233
E61.4 Chromium deficiency
0.000 0.767 0.233
E61.3 Manganese deficiency
0.000 0.767 0.233
E61.0 Copper deficiency
0.000 0.767 0.233
E85.3 Secondary systemic amyloidosis
0.001 0.769 0.231
E61.1 Iron deficiency
0.000 0.769 0.231
E87.6 Hypokalaemia
0.000 0.774 0.226
E29.1 Testicular hypofunction
0.000 0.779 0.221
E66.2 Extreme obesity with alveolar hypoventilation
0.001 0.781 0.219
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.787 0.213
E23.0 Hypopituitarism
0.000 0.791 0.208
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.796 0.204
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.796 0.204
E16.4 Abnormal secretion of gastrin
0.000 0.796 0.204
E16.3 Increased secretion of glucagon
0.000 0.796 0.204
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.796 0.204
E14.9 Without complications
0.000 0.805 0.195
E04.1 Non-toxic single thyroid nodule
0.000 0.808 0.192
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.808 0.192
E61.2 Magnesium deficiency
0.000 0.809 0.191
E55.0 Rickets, active
0.000 0.809 0.191
E89.2 Postprocedural hypoparathyroidism
0.002 0.809 0.189
E83.1 Disorders of iron metabolism
0.000 0.810 0.190
E21.0 Primary hyperparathyroidism
0.000 0.815 0.185
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.816 0.184
E13.9 Without complications
0.001 0.819 0.180
E04.2 Non-toxic multinodular goitre
0.000 0.825 0.175
G35 Multiple sclerosis
0.000 0.827 0.173
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.832 0.168
E16.1 Other hypoglycaemia
0.001 0.841 0.158
E16.2 Hypoglycaemia, unspecified
0.000 0.851 0.149
E78.1 Pure hyperglyceridaemia
0.000 0.856 0.143
E87.5 Hyperkalaemia
0.000 0.860 0.140
E07.9 Disorder of thyroid, unspecified
0.001 0.861 0.138
E78.3 Hyperchylomicronaemia
0.000 0.868 0.132
E78.4 Other hyperlipidaemia
0.000 0.868 0.132
E78.6 Lipoprotein deficiency
0.000 0.876 0.124
M06.9 Rheumatoid arthritis, unspecified
0.000 0.882 0.118
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.885 0.115
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.887 0.113
E78.2 Mixed hyperlipidaemia
0.000 0.893 0.107
Z88.0 Personal history of allergy to penicillin
0.107 0.893 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.895 0.104
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.896 0.103
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.900 0.100
E78.8 Other disorders of lipoprotein metabolism
0.000 0.902 0.098
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.903 0.097
E11 Non-insulin-dependent diabetes mellitus
0.000 0.906 0.094
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.910 0.090
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.911 0.089
E55.9 Vitamin D deficiency, unspecified
0.001 0.912 0.087
M06 Other rheumatoid arthritis
0.000 0.913 0.087
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.914 0.086
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.915 0.085
M06.0 Seronegative rheumatoid arthritis
0.000 0.917 0.083
E83.5 Disorders of calcium metabolism
0.000 0.920 0.080
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.920 0.080
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.922 0.078
E11.8 With unspecified complications
0.000 0.924 0.075
E11.1 With ketoacidosis
0.000 0.926 0.074
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.929 0.071
E11.3 With ophthalmic complications
0.000 0.930 0.070
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.930 0.070
E11.7 With multiple complications
0.000 0.932 0.067
E11.0 With coma
0.000 0.932 0.067
E11.2 With renal complications
0.000 0.934 0.066
M06.8 Other specified rheumatoid arthritis
0.000 0.938 0.062
M06.2 Rheumatoid bursitis
0.000 0.938 0.062
M06.1 Adult-onset Still's disease
0.000 0.938 0.062
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.940 0.060
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.940 0.060
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.940 0.060
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.940 0.060
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.940 0.060
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.940 0.060
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.940 0.060
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.940 0.060
M06.3 Rheumatoid nodule
0.000 0.941 0.059
G36 Other acute disseminated demyelination
0.000 0.950 0.050
M06.4 Inflammatory polyarthropathy
0.001 0.951 0.049
G37 Other demyelinating diseases of central nervous system
0.000 0.951 0.049
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.955 0.045
M06.18 Adult-onset Still's disease (Other)
0.000 0.955 0.045
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.955 0.045
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.955 0.045
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.955 0.045
M06.14 Adult-onset Still's disease (Hand)
0.000 0.955 0.045
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.955 0.045
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.955 0.045
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.955 0.045
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.955 0.045
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.955 0.045
M06.28 Rheumatoid bursitis (Other)
0.000 0.955 0.045
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.955 0.045
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.955 0.045
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.955 0.045
M06.24 Rheumatoid bursitis (Hand)
0.000 0.955 0.045
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.955 0.045
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.955 0.045
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.955 0.045
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.955 0.045
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.955 0.045
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.955 0.045
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.955 0.045
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.955 0.045
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.955 0.045
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.955 0.045
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.955 0.045
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.955 0.045
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.955 0.045
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.955 0.045
M06.34 Rheumatoid nodule (Hand)
0.000 0.956 0.043
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.957 0.042
M06.38 Rheumatoid nodule (Other)
0.000 0.957 0.042
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.957 0.042
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.957 0.042
M06.33 Rheumatoid nodule (Forearm)
0.000 0.957 0.042
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.957 0.042
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.957 0.042
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.957 0.042
H40.9 Glaucoma, unspecified
0.000 0.957 0.043
E11.6 With other specified complications
0.001 0.958 0.041
H40 Glaucoma
0.000 0.959 0.041
H40.0 Glaucoma suspect
0.000 0.961 0.039
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.961 0.038
E11.5 With peripheral circulatory complications
0.000 0.962 0.037
H40.2 Primary angle-closure glaucoma
0.000 0.963 0.037
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.963 0.036
G36.9 Acute disseminated demyelination, unspecified
0.000 0.964 0.036
G36.8 Other specified acute disseminated demyelination
0.000 0.964 0.036
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.964 0.036
G36.0 Neuromyelitis optica [Devic]
0.000 0.964 0.036
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.964 0.036
M06.48 Inflammatory polyarthropathy (Other)
0.001 0.964 0.035

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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