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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2844532
log Bayes Factor = 23.6794
Chromosome 6   position 31,351,175  (GRCh37) Explore rs2844532 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.002 0.998
L40 Psoriasis
0.000 0.004 0.996
L40.5 Arthropathic psoriasis
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.994 0.006 0.000
E10.4 With neurological complications
0.985 0.015 0.000
E10.1 With ketoacidosis
0.945 0.055 0.000
E10-E14 Diabetes mellitus
0.940 0.060 0.000
E10.0 With coma
0.922 0.078 0.000
E11 Non-insulin-dependent diabetes mellitus
0.859 0.141 0.000
E10.6 With other specified complications
0.832 0.168 0.000
E10.5 With peripheral circulatory complications
0.811 0.189 0.000
E10.2 With renal complications
0.800 0.200 0.000
E14 Unspecified diabetes mellitus
0.795 0.205 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.213 0.787
E10.8 With unspecified complications
0.785 0.215 0.000
E11.0 With coma
0.780 0.220 0.000
E13 Other specified diabetes mellitus
0.778 0.222 0.000
L40.8 Other psoriasis
0.000 0.222 0.777
E11.4 With neurological complications
0.777 0.223 0.000
E11.1 With ketoacidosis
0.774 0.226 0.000
E10.7 With multiple complications
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.000 0.286 0.714
L40.2 Acrodermatitis continua
0.000 0.286 0.714
L40.1 Generalised pustular psoriasis
0.000 0.286 0.714
E11.6 With other specified complications
0.699 0.301 0.000
M45 Ankylosing spondylitis
0.000 0.310 0.690
E14.1 With ketoacidosis
0.685 0.315 0.000
E12 Malnutrition-related diabetes mellitus
0.674 0.326 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.330 0.670
E14.6 With other specified complications
0.665 0.335 0.000
E13.9 Without complications
0.662 0.338 0.000
E14.2 Withrenal complications
0.631 0.369 0.000
L40.0 Psoriasis vulgaris
0.000 0.380 0.620
L40.3 Pustulosis palmaris et plantaris
0.000 0.382 0.617
E11.7 With multiple complications
0.616 0.384 0.000
E11.8 With unspecified complications
0.615 0.385 0.000
E14.4 With neurological complications
0.583 0.417 0.000
E03 Other hypothyroidism
0.010 0.426 0.563
E14.7 With multiple complications
0.570 0.430 0.000
E14.5 With peripheral circulatory complications
0.570 0.430 0.000
E14.0 With coma
0.570 0.430 0.000
E11.2 With renal complications
0.568 0.432 0.000
E14.8 With unspecified complications
0.565 0.435 0.000
E13.8 With unspecified complications
0.558 0.442 0.000
E13.7 With multiple complications
0.558 0.442 0.000
E13.6 With other specified complications
0.558 0.442 0.000
E13.5 With peripheral circulatory complications
0.558 0.442 0.000
E13.4 With neurological complications
0.558 0.442 0.000
E13.3 With ophthalmic complications
0.558 0.442 0.000
E13.2 With renal complications
0.558 0.442 0.000
E13.1 With ketoacidosis
0.558 0.442 0.000
E13.0 With coma
0.558 0.442 0.000
E11.3 With ophthalmic complications
0.547 0.453 0.000
E14.3 With ophthalmic complications
0.547 0.453 0.000
E16.2 Hypoglycaemia, unspecified
0.537 0.463 0.000
E16 Other disorders of pancreatic internal secretion
0.529 0.471 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.519 0.480 0.001
Chapter IV Endocrine, nutritional and metabolic diseases
0.513 0.485 0.002
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.505 0.495
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.505 0.495
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.505 0.495
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.505 0.495
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.505 0.495
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.505 0.495
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.505 0.495
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.505 0.495
E12.9 Without complications
0.483 0.517 0.000
E12.8 With unspecified complications
0.483 0.517 0.000
E12.7 With multiple complications
0.483 0.517 0.000
E12.6 With other specified complications
0.483 0.517 0.000
E12.5 With peripheral circulatory complications
0.483 0.517 0.000
E12.4 With neurological complications
0.483 0.517 0.000
E12.3 With ophthalmic complications
0.483 0.517 0.000
E12.2 With renal complications
0.483 0.517 0.000
E12.1 With ketoacidosis
0.483 0.517 0.000
E12.0 With coma
0.483 0.517 0.000
L40-L45 Papulosquamous disorders
0.000 0.558 0.442
E16.0 Drug-induced hypoglycaemia without coma
0.435 0.565 0.000
E11.5 With peripheral circulatory complications
0.434 0.566 0.000
E03.8 Other specified hypothyroidism
0.006 0.576 0.418
E03.5 Myxoedema coma
0.007 0.589 0.404
E03.4 Atrophy of thyroid (acquired)
0.007 0.589 0.404
E03.3 Postinfectious hypothyroidism
0.007 0.589 0.404
E03.1 Congenital hypothyroidism without goitre
0.007 0.589 0.404
E40-E46 Malnutrition
0.404 0.595 0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.007 0.617 0.376
E16.9 Disorder of pancreatic internal secretion, unspecified
0.379 0.621 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.379 0.621 0.000
E16.4 Abnormal secretion of gastrin
0.379 0.621 0.000
E16.3 Increased secretion of glucagon
0.379 0.621 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.008 0.626 0.366
E16.1 Other hypoglycaemia
0.373 0.627 0.000
E15 Nondiabetic hypoglycaemic coma
0.372 0.627 0.001
E00-E07 Disorders of thyroid gland
0.025 0.649 0.326
E46 Unspecified protein-energy malnutrition
0.325 0.674 0.001
E14.9 Without complications
0.323 0.677 0.000
L44 Other papulosquamous disorders
0.000 0.683 0.317
L41 Parapsoriasis
0.000 0.683 0.317
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.683 0.317
E06 Thyroiditis
0.013 0.693 0.295
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.695 0.305
L20-L30 Dermatitis and eczema
0.000 0.697 0.303
E65-E68 Obesity and other hyperalimentation
0.302 0.697 0.001
L27 Dermatitis due to substances taken internally
0.000 0.702 0.298
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.705 0.295
E44 Protein-energy malnutrition of moderate and mild degree
0.290 0.709 0.001
E45 Retarded development following protein-energy malnutrition
0.290 0.709 0.001
E43 Unspecified severe protein-energy malnutrition
0.290 0.709 0.001
E42 Marasmic kwashiorkor
0.290 0.709 0.001
E41 Nutritional marasmus
0.290 0.709 0.001
E40 Kwashiorkor
0.290 0.709 0.001
L30 Other dermatitis
0.000 0.712 0.288
L42 Pityriasis rosea
0.000 0.716 0.284
L30.9 Dermatitis, unspecified
0.000 0.717 0.283
E06.3 Autoimmune thyroiditis
0.002 0.718 0.280
E07 Other disorders of thyroid
0.011 0.737 0.252
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.742 0.258
E02 Subclinical iodine-deficiency hypothyroidism
0.017 0.746 0.237
E50-E64 Other nutritional deficiencies
0.252 0.747 0.001
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.018 0.748 0.234
E00 Congenital iodine-deficiency syndrome
0.018 0.748 0.234
E65 Localised adiposity
0.251 0.749 0.001
L50-L54 Urticaria and erythema
0.000 0.761 0.239
L20 Atopic dermatitis
0.000 0.763 0.237
E07.8 Other specified disorders of thyroid
0.005 0.770 0.225
L41.9 Parapsoriasis, unspecified
0.000 0.772 0.227
L41.8 Other parapsoriasis
0.000 0.772 0.227
L41.5 Retiform parapsoriasis
0.000 0.772 0.227
L41.4 Large plaque parapsoriasis
0.000 0.772 0.227
L41.3 Small plaque parapsoriasis
0.000 0.772 0.227
L41.2 Lymphomatoid papulosis
0.000 0.772 0.227
L41.1 Pityriasis lichenoides chronica
0.000 0.772 0.227
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.772 0.227
L44.9 Papulosquamous disorder, unspecified
0.000 0.772 0.227
L44.8 Other specified papulosquamous disorders
0.000 0.772 0.227
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.772 0.227
L44.3 Lichen ruber moniliformis
0.000 0.772 0.227
L44.2 Lichen striatus
0.000 0.772 0.227
L44.1 Lichen nitidus
0.000 0.772 0.227
L44.0 Pityriasis rubra pilaris
0.000 0.772 0.227
L23 Allergic contact dermatitis
0.000 0.774 0.226
L21 Seborrhoeic dermatitis
0.000 0.776 0.224
L10-L14 Bullous disorders
0.000 0.776 0.223
E06.5 Other chronic thyroiditis
0.009 0.779 0.211
E06.4 Drug-induced thyroiditis
0.009 0.779 0.211
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.009 0.779 0.211
E06.1 Subacute thyroiditis
0.009 0.779 0.211
E06.0 Acute thyroiditis
0.009 0.779 0.211
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.780 0.220
L24 Irritant contact dermatitis
0.000 0.782 0.218
L26 Exfoliative dermatitis
0.000 0.782 0.218
L22 Diaper [napkin] dermatitis
0.000 0.782 0.218
E67 Other hyperalimentation
0.217 0.782 0.001
E68 Sequelae of hyperalimentation
0.217 0.782 0.001
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.786 0.214
L27.8 Dermatitis due to other substances taken internally
0.000 0.786 0.214
L27.2 Dermatitis due to ingested food
0.000 0.786 0.214
L27.1 Localised skin eruption due to drugs and medicaments
0.000 0.787 0.213
E44.1 Mild protein-energy malnutrition
0.208 0.791 0.001
E44.0 Moderate protein-energy malnutrition
0.208 0.791 0.001
L30.5 Pityriasis alba
0.000 0.793 0.207
L30.3 Infective dermatitis
0.000 0.793 0.207
L30.2 Cutaneous autosensitisation
0.000 0.793 0.207
L30.1 Dyshidrosis [pompholyx]
0.000 0.793 0.207
L30.0 Nummular dermatitis
0.000 0.793 0.207
E54 Ascorbic acid deficiency
0.204 0.795 0.001
L52 Erythema nodosum
0.000 0.796 0.204
L25 Unspecified contact dermatitis
0.000 0.802 0.198
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.806 0.194
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.807 0.193
L20.9 Atopic dermatitis, unspecified
0.000 0.810 0.190
L30.8 Other specified dermatitis
0.000 0.811 0.189
E07.1 Dyshormogenetic goitre
0.008 0.811 0.181
E07.0 Hypersecretion of calcitonin
0.008 0.811 0.181
L28 Lichen simplex chronicus and prurigo
0.000 0.812 0.188
L50 Urticaria
0.000 0.812 0.188
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.815 0.185
L58 Radiodermatitis
0.000 0.815 0.185
L55 Sunburn
0.000 0.815 0.185
E06.9 Thyroiditis, unspecified
0.010 0.817 0.174
L23.1 Allergic contact dermatitis due to adhesives
0.000 0.818 0.181
E64 Sequelae of malnutrition and other nutritional deficiencies
0.181 0.819 0.001
E63 Other nutritional deficiencies
0.181 0.819 0.001
E56 Other vitamin deficiencies
0.181 0.819 0.001
E51 Thiamine deficiency
0.181 0.819 0.001
E50 Vitamin A deficiency
0.181 0.819 0.001
E60 Dietary zinc deficiency
0.181 0.819 0.001
E59 Dietary selenium deficiency
0.181 0.819 0.001
E58 Dietary calcium deficiency
0.181 0.819 0.001
E52 Niacin deficiency [pellagra]
0.181 0.819 0.001
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.013 0.819 0.168
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.013 0.819 0.168
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.013 0.819 0.168
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.013 0.819 0.168
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.013 0.819 0.168
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.013 0.819 0.168
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.013 0.819 0.168
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.013 0.819 0.168
L30.4 Erythema intertrigo
0.000 0.824 0.176
L57.0 Actinic keratosis
0.000 0.825 0.175
L54 Erythema in diseases classified elsewhere
0.000 0.829 0.171
E05 Thyrotoxicosis [hyperthyroidism]
0.011 0.829 0.160
L20.8 Other atopic dermatitis
0.000 0.830 0.170
L20.0 Besnier's prurigo
0.000 0.830 0.170
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.833 0.167
L12 Pemphigoid
0.000 0.834 0.166
L23.9 Allergic contact dermatitis, unspecified cause
0.000 0.838 0.162
L23.8 Allergic contact dermatitis due to other agents
0.000 0.838 0.162
L23.7 Allergic contact dermatitis due to plants, except food
0.000 0.838 0.162
L23.6 Allergic contact dermatitis due to food in contact with the skin
0.000 0.838 0.162
L23.4 Allergic contact dermatitis due to dyes
0.000 0.838 0.162
L23.3 Allergic contact dermatitis due to drugs in contact with the skin
0.000 0.838 0.162
L23.2 Allergic contact dermatitis due to cosmetics
0.000 0.838 0.162
L23.0 Allergic contact dermatitis due to metals
0.000 0.838 0.162
L21.8 Other seborrhoeic dermatitis
0.000 0.839 0.161
L21.1 Seborrhoeic infantile dermatitis
0.000 0.839 0.161
L21.0 Seborrhoea capitis
0.000 0.839 0.161
L11 Other acantholytic disorders
0.000 0.839 0.160
L10 Pemphigus
0.000 0.839 0.160
L14 Bullous disorders in diseases classified elsewhere
0.000 0.839 0.160
L51 Erythema multiforme
0.000 0.840 0.159
L13 Other bullous disorders
0.000 0.841 0.159
L50.1 Idiopathic urticaria
0.000 0.842 0.158
L57.5 Actinic granuloma
0.000 0.842 0.158
L57.3 Poikiloderma of Civatte
0.000 0.842 0.158
L57.2 Cutis rhomboidalis nuchae
0.000 0.842 0.158
L57.1 Actinic reticuloid
0.000 0.842 0.158
L24.9 Irritant contact dermatitis, unspecified cause
0.000 0.844 0.156
L24.8 Irritant contact dermatitis due to other agents
0.000 0.844 0.156
L24.7 Irritant contact dermatitis due to plants, except food
0.000 0.844 0.156
L24.6 Irritant contact dermatitis due to food in contact with the skin
0.000 0.844 0.156
L24.5 Irritant contact dermatitis due to other chemical products
0.000 0.844 0.156
L24.4 Irritant contact dermatitis due to drugs in contact with the skin
0.000 0.844 0.156
L24.3 Irritant contact dermatitis due to cosmetics
0.000 0.844 0.156
L24.2 Irritant contact dermatitis due to solvents
0.000 0.844 0.156
L24.1 Irritant contact dermatitis due to oils and greases
0.000 0.844 0.156
L24.0 Irritant contact dermatitis due to detergents
0.000 0.844 0.156
E67.8 Other specified hyperalimentation
0.155 0.844 0.001
E67.3 Hypervitaminosis D
0.155 0.844 0.001
E67.2 Megavitamin-B6 syndrome
0.155 0.844 0.001
E67.1 Hypercarotenaemia
0.155 0.844 0.001
E67.0 Hypervitaminosis A
0.155 0.844 0.001
L43 Lichen planus
0.001 0.845 0.154
E55 Vitamin D deficiency
0.152 0.848 0.001
L57.4 Cutis laxa senilis
0.000 0.851 0.149
L23.5 Allergic contact dermatitis due to other chemical products
0.000 0.854 0.146
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.854 0.146
L50.8 Other urticaria
0.000 0.857 0.143
L25.8 Unspecified contact dermatitis due to other agents
0.000 0.858 0.142
L25.5 Unspecified contact dermatitis due to plants, except food
0.000 0.858 0.142
L25.4 Unspecified contact dermatitis due to food in contact with the skin
0.000 0.858 0.142
L25.3 Unspecified contact dermatitis due to other chemical products
0.000 0.858 0.142
L25.2 Unspecified contact dermatitis due to dyes
0.000 0.858 0.142
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin
0.000 0.858 0.142
L25.0 Unspecified contact dermatitis due to cosmetics
0.000 0.858 0.142
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.859 0.141
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.859 0.141
L60-L75 Disorders of skin appendages
0.000 0.859 0.141
L56.4 Polymorphous light eruption
0.000 0.861 0.139
L56.3 Solar urticaria
0.000 0.861 0.139
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.861 0.139
L56.1 Drug photoallergic response
0.000 0.861 0.139
L56.0 Drug phototoxic response
0.000 0.861 0.139
L50.9 Urticaria, unspecified
0.000 0.865 0.135
L28.2 Other prurigo
0.000 0.865 0.135
L50.6 Contact urticaria
0.000 0.865 0.135
L50.5 Cholinergic urticaria
0.000 0.865 0.135
L50.4 Vibratory urticaria
0.000 0.865 0.135
L50.3 Dermatographic urticaria
0.000 0.865 0.135
L50.2 Urticaria due to cold and heat
0.000 0.865 0.135
L53 Other erythematous conditions
0.000 0.865 0.135
E61 Deficiency of other nutrient elements
0.134 0.865 0.001
E04 Other non-toxic goitre
0.003 0.866 0.130
L55.9 Sunburn, unspecified
0.000 0.867 0.133
L55.8 Other sunburn
0.000 0.867 0.133
L55.2 Sunburn of third degree
0.000 0.867 0.133
L55.1 Sunburn of second degree
0.000 0.867 0.133
L55.0 Sunburn of first degree
0.000 0.867 0.133
L58.9 Radiodermatitis, unspecified
0.000 0.867 0.133
L58.1 Chronic radiodermatitis
0.000 0.867 0.133
L58.0 Acute radiodermatitis
0.000 0.867 0.133
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.000 0.867 0.133
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.000 0.867 0.133
L59.0 Erythema ab igne [dermatitis ab igne]
0.000 0.867 0.133
J45.9 Asthma, unspecified
0.133 0.867 0.000
E53 Deficiency of other B group vitamins
0.131 0.868 0.001
E50.9 Vitamin A deficiency, unspecified
0.130 0.870 0.001
E50.8 Other manifestations of vitamin A deficiency
0.130 0.870 0.001
E50.7 Other ocular manifestations of vitamin A deficiency
0.130 0.870 0.001
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.130 0.870 0.001
E50.5 Vitamin A deficiency with night blindness
0.130 0.870 0.001
E50.4 Vitamin A deficiency with keratomalacia
0.130 0.870 0.001
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.130 0.870 0.001
E50.2 Vitamin A deficiency with corneal xerosis
0.130 0.870 0.001
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.130 0.870 0.001
E50.0 Vitamin A deficiency with conjunctival xerosis
0.130 0.870 0.001
E51.9 Thiamine deficiency, unspecified
0.130 0.870 0.001
E51.8 Other manifestations of thiamine deficiency
0.130 0.870 0.001
E51.2 Wernicke's encephalopathy
0.130 0.870 0.001
E51.1 Beriberi
0.130 0.870 0.001
E56.9 Vitamin deficiency, unspecified
0.130 0.870 0.001
E56.8 Deficiency of other vitamins
0.130 0.870 0.001
E56.1 Deficiency of vitamin K
0.130 0.870 0.001
E56.0 Deficiency of vitamin E
0.130 0.870 0.001
E63.9 Nutritional deficiency, unspecified
0.130 0.870 0.001
E63.8 Other specified nutritional deficiencies
0.130 0.870 0.001
E63.1 Imbalance of constituents of food intake
0.130 0.870 0.001
E63.0 Essential fatty acid [EFA] deficiency
0.130 0.870 0.001
E64.9 Sequelae of unspecified nutritional deficiency
0.130 0.870 0.001
E64.8 Sequelae of other nutritional deficiencies
0.130 0.870 0.001
E64.3 Sequelae of rickets
0.130 0.870 0.001
E64.2 Sequelae of vitamin C deficiency
0.130 0.870 0.001
E64.1 Sequelae of vitamin A deficiency
0.130 0.870 0.001
E64.0 Sequelae of protein-energy malnutrition
0.130 0.870 0.001
L28.1 Prurigo nodularis
0.000 0.873 0.127
L12.0 Bullous pemphigoid
0.000 0.875 0.125
L54.8 Erythema in other diseases classified elsewhere
0.000 0.877 0.123
L54.0 Erythema marginatum in acute rheumatic fever
0.000 0.877 0.123
E05.5 Thyroid crisis or storm
0.008 0.877 0.115
E05.4 Thyrotoxicosis factitia
0.008 0.877 0.115
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.008 0.877 0.115
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.008 0.877 0.115
L25.9 Unspecified contact dermatitis, unspecified cause
0.000 0.878 0.122
E07.9 Disorder of thyroid, unspecified
0.006 0.879 0.115
E05.0 Thyrotoxicosis with diffuse goitre
0.003 0.881 0.117
L12.9 Pemphigoid, unspecified
0.000 0.881 0.119
L12.8 Other pemphigoid
0.000 0.881 0.119
L12.3 Acquired epidermolysis bullosa
0.000 0.881 0.119
L12.2 Chronic bullous disease of childhood
0.000 0.881 0.119
L12.1 Cicatricial pemphigoid
0.000 0.881 0.119
E05.9 Thyrotoxicosis, unspecified
0.001 0.881 0.119
L28.0 Lichen simplex chronicus
0.000 0.883 0.117
L11.0 Acquired keratosis follicularis
0.000 0.884 0.115
L11.9 Acantholytic disorder, unspecified
0.000 0.885 0.115
L11.8 Other specified acantholytic disorders
0.000 0.885 0.115
L11.1 Transient acantholytic dermatosis [Grover]
0.000 0.885 0.115
L10.9 Pemphigus, unspecified
0.000 0.885 0.115
L10.8 Other pemphigus
0.000 0.885 0.115
L10.5 Drug-induced pemphigus
0.000 0.885 0.115
L10.4 Pemphigus erythematosus
0.000 0.885 0.115
L10.3 Brazilian pemphigus [fogo selvagem]
0.000 0.885 0.115
L10.2 Pemphigus foliaceus
0.000 0.885 0.115
L10.1 Pemphigus vegetans
0.000 0.885 0.115
L10.0 Pemphigus vulgaris
0.000 0.885 0.115
L51.8 Other erythema multiforme
0.000 0.885 0.114
L51.2 Toxic epidermal necrolysis [Lyell]
0.000 0.885 0.114
L51.0 Nonbullous erythema multiforme
0.000 0.885 0.114
L13.9 Bullous disorder, unspecified
0.000 0.886 0.114
L13.8 Other specified bullous disorders
0.000 0.886 0.114
L13.1 Subcorneal pustular dermatitis
0.000 0.886 0.114
L51.9 Erythema multiforme, unspecified
0.000 0.887 0.113
L50.0 Allergic urticaria
0.000 0.887 0.113
L13.0 Dermatitis herpetiformis
0.000 0.887 0.113
L60 Nail disorders
0.000 0.887 0.113
L43.3 Subacute (active) lichen planus
0.001 0.889 0.111
L43.2 Lichenoid drug reaction
0.001 0.889 0.111
L43.1 Bullous lichen planus
0.001 0.889 0.111
L43.0 Hypertrophic lichen planus
0.001 0.889 0.111
E04.0 Non-toxic diffuse goitre
0.002 0.890 0.109
E55.0 Rickets, active
0.109 0.890 0.001
L53.8 Other specified erythematous conditions
0.000 0.892 0.108
L29 Pruritus
0.000 0.893 0.107
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.895 0.105
L51.1 Bullous erythema multiforme
0.000 0.896 0.104
L71 Rosacea
0.000 0.896 0.104
L75 Apocrine sweat disorders
0.000 0.899 0.101
L74 Eccrine sweat disorders
0.000 0.899 0.101
L68 Hypertrichosis
0.000 0.899 0.101
L67 Hair colour and hair shaft abnormalities
0.000 0.899 0.101
L66 Cicatricial alopecia [scarring hair loss]
0.000 0.899 0.101
L64 Androgenic alopecia
0.000 0.899 0.101
L63 Alopecia areata
0.000 0.899 0.101
L62 Nail disorders in diseases classified elsewhere
0.000 0.899 0.101
E53.9 Vitamin B deficiency, unspecified
0.100 0.900 0.000
L65 Other nonscarring hair loss
0.000 0.900 0.100
L60.2 Onychogryphosis
0.000 0.901 0.099
L73 Other follicular disorders
0.000 0.901 0.099
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.008 0.901 0.090
L53.3 Other chronic figurate erythema
0.000 0.903 0.097
L53.2 Erythema marginatum
0.000 0.903 0.097
L53.1 Erythema annulare centrifugum
0.000 0.903 0.097
L53.0 Toxic erythema
0.000 0.903 0.097
E61.9 Deficiency of nutrient element, unspecified
0.096 0.903 0.001
E61.8 Deficiency of other specified nutrient elements
0.096 0.903 0.001
E61.7 Deficiency of multiple nutrient elements
0.096 0.903 0.001
E61.6 Vanadium deficiency
0.096 0.903 0.001
E61.5 Molybdenum deficiency
0.096 0.903 0.001
E61.4 Chromium deficiency
0.096 0.903 0.001
E61.3 Manganese deficiency
0.096 0.903 0.001
E61.0 Copper deficiency
0.096 0.903 0.001
E04.8 Other specified non-toxic goitre
0.002 0.904 0.094
E53.1 Pyridoxine deficiency
0.094 0.905 0.001
E53.0 Riboflavin deficiency
0.094 0.905 0.001
J45 Asthma
0.094 0.906 0.000
L70 Acne
0.000 0.907 0.093
L60.9 Nail disorder, unspecified
0.000 0.908 0.092
L60.3 Nail dystrophy
0.000 0.909 0.091
E61.2 Magnesium deficiency
0.086 0.913 0.001
L43.8 Other lichen planus
0.001 0.915 0.084
L73.2 Hidradenitis suppurativa
0.000 0.918 0.082
E05.8 Other thyrotoxicosis
0.010 0.918 0.071
L60.5 Yellow nail syndrome
0.000 0.919 0.081
L60.4 Beau's lines
0.000 0.919 0.081
L60.1 Onycholysis
0.000 0.919 0.081
J45.1 Nonallergic asthma
0.081 0.919 0.000
E55.9 Vitamin D deficiency, unspecified
0.080 0.920 0.000
L08 Other local infections of skin and subcutaneous tissue
0.000 0.921 0.079
L71.1 Rhinophyma
0.000 0.921 0.079
J45.8 Mixed asthma
0.079 0.921 0.000
L04 Acute lymphadenitis
0.000 0.922 0.078
L29.3 Anogenital pruritus, unspecified
0.000 0.923 0.077
L29.1 Pruritus scroti
0.000 0.923 0.077
E20-E35 Disorders of other endocrine glands
0.075 0.923 0.002
E04.2 Non-toxic multinodular goitre
0.001 0.924 0.075
L01 Impetigo
0.000 0.924 0.076
L00 Staphylococcal scalded skin syndrome
0.000 0.924 0.076
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.924 0.076
L29.0 Pruritus ani
0.000 0.924 0.075
L71.8 Other rosacea
0.000 0.925 0.075
L71.0 Perioral dermatitis
0.000 0.925 0.075
L62.8 Nail disorders in other diseases classified elsewhere
0.000 0.927 0.073
L62.0 Clubbed nail pachydermoperiostosis
0.000 0.927 0.073
L63.9 Alopecia areata, unspecified
0.000 0.927 0.073
L63.8 Other alopecia areata
0.000 0.927 0.073
L63.2 Ophiasis
0.000 0.927 0.073
L63.1 Alopecia universalis
0.000 0.927 0.073
L63.0 Alopecia (capitis) totalis
0.000 0.927 0.073
L64.9 Androgenic alopecia, unspecified
0.000 0.927 0.073
L64.8 Other androgenic alopecia
0.000 0.927 0.073
L64.0 Drug-induced androgenic alopecia
0.000 0.927 0.073
L66.9 Cicatricial alopecia, unspecified
0.000 0.927 0.073
L66.8 Other cicatricial alopecia
0.000 0.927 0.073
L66.4 Folliculitis ulerythematosa reticulata
0.000 0.927 0.073
L66.3 Perifolliculitis capitis abscedens
0.000 0.927 0.073
L66.2 Folliculitis decalvans
0.000 0.927 0.073
L66.1 Lichen planopilaris
0.000 0.927 0.073
L66.0 Pseudopelade
0.000 0.927 0.073
L67.9 Hair colour and hair shaft abnormality, unspecified
0.000 0.927 0.073
L67.8 Other hair colour and hair shaft abnormalities
0.000 0.927 0.073
L67.1 Variations in hair colour
0.000 0.927 0.073
L67.0 Trichorrhexis nodosa
0.000 0.927 0.073
L68.9 Hypertrichosis, unspecified
0.000 0.927 0.073
L68.8 Other hypertrichosis
0.000 0.927 0.073
L68.3 Polytrichia
0.000 0.927 0.073
L68.2 Localised hypertrichosis
0.000 0.927 0.073
L68.1 Acquired hypertrichosis lanuginosa
0.000 0.927 0.073
L68.0 Hirsutism
0.000 0.927 0.073
L74.9 Eccrine sweat disorder, unspecified
0.000 0.927 0.073
L74.8 Other eccrine sweat disorders
0.000 0.927 0.073
L74.4 Anhidrosis
0.000 0.927 0.073
L74.3 Miliaria, unspecified
0.000 0.927 0.073
L74.2 Miliaria profunda
0.000 0.927 0.073
L74.1 Miliaria crystallina
0.000 0.927 0.073
L74.0 Miliaria rubra
0.000 0.927 0.073
L75.9 Apocrine sweat disorder, unspecified
0.000 0.927 0.073
L75.8 Other apocrine sweat disorders
0.000 0.927 0.073
L75.2 Apocrine miliaria
0.000 0.927 0.073
L75.1 Chromhidrosis
0.000 0.927 0.073
L75.0 Bromhidrosis
0.000 0.927 0.073
L71.9 Rosacea, unspecified
0.000 0.927 0.073
L65.8 Other specified nonscarring hair loss
0.000 0.928 0.072
L65.2 Alopecia mucinosa
0.000 0.928 0.072
L65.1 Anagen effluvium
0.000 0.928 0.072
L65.0 Telogen effluvium
0.000 0.928 0.072
L73.1 Pseudofolliculitis barbae
0.000 0.929 0.071
L73.0 Acne keloid
0.000 0.929 0.071
L60.8 Other nail disorders
0.000 0.929 0.071
L73.9 Follicular disorder, unspecified
0.000 0.929 0.071
L65.9 Nonscarring hair loss, unspecified
0.000 0.930 0.070
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.932 0.068
L29.8 Other pruritus
0.000 0.933 0.067
L70.9 Acne, unspecified
0.000 0.933 0.067
E61.1 Iron deficiency
0.066 0.933 0.001
L70.8 Other acne
0.000 0.933 0.067
L70.5 Acne excoriee des jeunes filles
0.000 0.933 0.067
L70.4 Infantile acne
0.000 0.933 0.067
L70.3 Acne tropica
0.000 0.933 0.067
L70.2 Acne varioliformis
0.000 0.933 0.067
L70.1 Acne conglobata
0.000 0.933 0.067
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.934 0.066
J45.0 Predominantly allergic asthma
0.065 0.935 0.000
E24 Cushing's syndrome
0.063 0.936 0.001
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.938 0.062
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.940 0.060
E04.9 Non-toxic goitre, unspecified
0.001 0.940 0.058
L04.0 Acute lymphadenitis of face, head and neck
0.000 0.942 0.058
L70.0 Acne vulgaris
0.000 0.942 0.058
L08.1 Erythrasma
0.000 0.943 0.057
L08.0 Pyoderma
0.000 0.943 0.057
L04.8 Acute lymphadenitis of other sites
0.000 0.944 0.056
L04.3 Acute lymphadenitis of lower limb
0.000 0.944 0.056
L04.2 Acute lymphadenitis of upper limb
0.000 0.944 0.056
L04.1 Acute lymphadenitis of trunk
0.000 0.944 0.056
L04.9 Acute lymphadenitis, unspecified
0.000 0.944 0.056
E24.9 Cushing's syndrome, unspecified
0.055 0.944 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.054 0.945 0.001
E32 Diseases of thymus
0.054 0.945 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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