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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2844575
log Bayes Factor = 95.9248
Chromosome 6   position 31,334,945  (GRCh37) Explore rs2844575 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
M45 Ankylosing spondylitis
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
0.000 0.001 0.999
M20-M25 Other joint disorders
0.000 0.001 0.999
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.001 0.999
M45-M49 Spondylopathies
0.000 0.002 0.998
K51.9 Ulcerative colitis, unspecified
0.000 0.002 0.998
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.002 0.998
K51 Ulcerative colitis
0.000 0.002 0.998
Chapter VII Diseases of the eye and adnexa
0.000 0.002 0.998
H20 Iridocyclitis
0.000 0.003 0.997
D80-D89 Certain disorders involving the immune mechanism
0.000 0.005 0.995
H20.9 Iridocyclitis, unspecified
0.000 0.006 0.994
E50-E64 Other nutritional deficiencies
0.000 0.008 0.992
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.009 0.991
M07.3 Other psoriatic arthropathies
0.000 0.012 0.988
K90 Intestinal malabsorption
0.000 0.012 0.988
D69 Purpura and other haemorrhagic conditions
0.000 0.013 0.987
M07 Psoriatic and enteropathic arthropathies
0.000 0.016 0.984
M05-M14 Inflammatory polyarthropathies
0.000 0.018 0.982
E53 Deficiency of other B group vitamins
0.000 0.020 0.980
K51.4 Pseudopolyposis of colon
0.000 0.021 0.979
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.022 0.978
D50-D53 Nutritional anaemias
0.000 0.022 0.978
M00-M03 Infectious arthropathies
0.000 0.022 0.978
K50-K52 Noninfective enteritis and colitis
0.000 0.024 0.976
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.025 0.975
Chapter XI Diseases of the digestive system
0.000 0.028 0.972
K90-K93 Other diseases of the digestive system
0.000 0.028 0.972
E53.8 Deficiency of other specified B group vitamins
0.000 0.029 0.971
D50 Iron deficiency anaemia
0.000 0.034 0.966
D69.6 Thrombocytopenia, unspecified
0.000 0.034 0.966
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.036 0.964
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.042 0.958
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.043 0.957
E06 Thyroiditis
0.000 0.044 0.956
M35.7 Hypermobility syndrome
0.000 0.044 0.956
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.048 0.952
H05 Disorders of orbit
0.000 0.051 0.949
D86 Sarcoidosis
0.000 0.055 0.945
M34 Systemic sclerosis
0.000 0.057 0.943
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.059 0.941
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.059 0.941
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.071 0.929
Chapter VI Diseases of the nervous system
0.000 0.074 0.926
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.076 0.924
M02 Reactive arthropathies
0.000 0.085 0.915
H05.0 Acute inflammation of orbit
0.000 0.089 0.911
H55-H59 Other disorders of eye and adnexa
0.000 0.090 0.910
H02.0 Entropion and trichiasis of eyelid
0.000 0.090 0.910
D50.9 Iron deficiency anaemia, unspecified
0.000 0.091 0.909
D86.9 Sarcoidosis, unspecified
0.000 0.092 0.908
H18 Other disorders of cornea
0.000 0.092 0.908
M00 Pyogenic arthritis
0.000 0.093 0.907
H02 Other disorders of eyelid
0.000 0.095 0.905
D69.5 Secondary thrombocytopenia
0.000 0.103 0.897
E06.3 Autoimmune thyroiditis
0.000 0.109 0.891
D69.2 Other nonthrombocytopenic purpura
0.000 0.114 0.886
H57 Other disorders of eye and adnexa
0.000 0.118 0.882
H16 Keratitis
0.000 0.120 0.880
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.127 0.873
H57.1 Ocular pain
0.000 0.130 0.870
L40-L45 Papulosquamous disorders
0.000 0.131 0.869
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.131 0.869
M34.8 Other forms of systemic sclerosis
0.000 0.134 0.866
H20.1 Chronic iridocyclitis
0.000 0.136 0.864
M00.9 Pyogenic arthritis, unspecified
0.000 0.140 0.860
L50-L54 Urticaria and erythema
0.000 0.140 0.860
E06.9 Thyroiditis, unspecified
0.000 0.144 0.856
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.144 0.856
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.147 0.853
H05.2 Exophthalmic conditions
0.000 0.156 0.844
K51.5 Mucosal proctocolitis
0.000 0.156 0.844
D86.0 Sarcoidosis of lung
0.000 0.157 0.843
H20.0 Acute and subacute iridocyclitis
0.000 0.157 0.843
H02.5 Other disorders affecting eyelid function
0.000 0.158 0.842
D80 Immunodeficiency with predominantly antibody defects
0.000 0.158 0.842
L40 Psoriasis
0.000 0.162 0.838
E55 Vitamin D deficiency
0.000 0.163 0.837
L40.5 Arthropathic psoriasis
0.000 0.167 0.833
H21 Other disorders of iris and ciliary body
0.000 0.170 0.830
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.173 0.826
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.177 0.823
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.181 0.819
M24 Other specific joint derangements
0.000 0.181 0.819
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.182 0.818
D69.4 Other primary thrombocytopenia
0.000 0.182 0.818
M02.3 Reiter's disease
0.000 0.183 0.817
M11 Other crystal arthropathies
0.000 0.184 0.816
M60-M63 Disorders of muscles
0.000 0.184 0.816
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.184 0.816
K51.8 Other ulcerative colitis
0.000 0.187 0.812
D84 Other immunodeficiencies
0.000 0.188 0.812
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.000 0.189 0.811
H18.6 Keratoconus
0.000 0.197 0.803
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.197 0.803
H20.8 Other iridocyclitis
0.000 0.198 0.802
L52 Erythema nodosum
0.000 0.201 0.799
M02.9 Reactive arthopathy, unspecified
0.000 0.202 0.798
M33 Dermatopolymyositis
0.000 0.208 0.792
H01 Other inflammation of eyelid
0.000 0.211 0.789
D83 Common variable immunodeficiency
0.000 0.212 0.788
K90.9 Intestinal malabsorption, unspecified
0.000 0.214 0.786
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.216 0.784
E03.8 Other specified hypothyroidism
0.000 0.216 0.784
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.221 0.779
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.222 0.778
H18.3 Changes in corneal membranes
0.000 0.223 0.777
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.224 0.776
H18.1 Bullous keratopathy
0.000 0.225 0.775
M34.1 CR(E)ST syndrome
0.000 0.225 0.775
L10-L14 Bullous disorders
0.000 0.229 0.771
H06.2 Dysthyroid exophthalmos
0.000 0.236 0.764
E56 Other vitamin deficiencies
0.000 0.238 0.762
D60-D64 Aplastic and other anaemias
0.000 0.239 0.761
L20-L30 Dermatitis and eczema
0.000 0.243 0.757
H21.5 Other adhesions and disruptions of iris and ciliary body
0.000 0.243 0.757
H16.0 Corneal ulcer
0.000 0.243 0.757
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.244 0.756
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.245 0.755
E51 Thiamine deficiency
0.000 0.246 0.754
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.252 0.748
M24.5 Contracture of joint
0.000 0.253 0.747
M21 Other acquired deformities of limbs
0.000 0.254 0.746
M02.39 Reiter's disease (Site unspecified)
0.000 0.254 0.746
M30 Polyarteritis nodosa and related conditions
0.000 0.254 0.746
H18.0 Corneal pigmentations and deposits
0.000 0.255 0.745
G30-G32 Other degenerative diseases of the nervous system
0.000 0.255 0.745
H16.9 Keratitis, unspecified
0.000 0.255 0.745
G36 Other acute disseminated demyelination
0.000 0.257 0.743
K51.2 Ulcerative (chronic) proctitis
0.000 0.259 0.741
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.260 0.740
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.261 0.739
H05.4 Enophthalmos
0.000 0.263 0.737
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.263 0.737
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.264 0.736
G37 Other demyelinating diseases of central nervous system
0.000 0.264 0.736
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.000 0.266 0.734
H18.2 Other corneal oedema
0.000 0.268 0.732
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.270 0.730
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.000 0.270 0.730
D61 Other aplastic anaemias
0.000 0.271 0.729
D55-D59 Haemolytic anaemias
0.000 0.273 0.727
E53.9 Vitamin B deficiency, unspecified
0.000 0.274 0.726
E55.9 Vitamin D deficiency, unspecified
0.000 0.274 0.726
D66 Hereditary factor VIII deficiency
0.000 0.274 0.725
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.275 0.725
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.275 0.725
L50 Urticaria
0.000 0.275 0.725
M07.6 Other enteropathic arthropathies
0.000 0.276 0.724
M34.9 Systemic sclerosis, unspecified
0.000 0.277 0.723
L57.0 Actinic keratosis
0.000 0.278 0.722
E61 Deficiency of other nutrient elements
0.000 0.278 0.722
M24.8 Other specific joint derangements, not elsewhere classified
0.000 0.279 0.721
E58 Dietary calcium deficiency
0.000 0.279 0.721
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.283 0.717
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.283 0.717
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.283 0.717
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.283 0.717
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.283 0.717
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.716
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.716
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.716
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.716
H21.8 Other specified disorders of iris and ciliary body
0.000 0.284 0.716
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.284 0.716
H57.8 Other specified disorders of eye and adnexa
0.000 0.285 0.715
H20.2 Lens-induced iridocyclitis
0.000 0.285 0.715
D81 Combined immunodeficiencies
0.000 0.287 0.713
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.288 0.712
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.288 0.712
M23 Internal derangement of knee
0.000 0.288 0.712
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.289 0.711
E63 Other nutritional deficiencies
0.000 0.289 0.711
E50 Vitamin A deficiency
0.000 0.289 0.711
E60 Dietary zinc deficiency
0.000 0.289 0.711
E59 Dietary selenium deficiency
0.000 0.289 0.711
E52 Niacin deficiency [pellagra]
0.000 0.289 0.711
D61.9 Aplastic anaemia, unspecified
0.000 0.289 0.711
M07.38 Other psoriatic arthropathies (Other)
0.000 0.292 0.708
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.292 0.708
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.292 0.708
K90.3 Pancreatic steatorrhoea
0.000 0.292 0.708
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.292 0.708
K90.1 Tropical sprue
0.000 0.292 0.708
D69.8 Other specified haemorrhagic conditions
0.000 0.293 0.707
M08 Juvenile arthritis
0.000 0.294 0.706
M07.5 Arthropathy in ulcerative colitis
0.000 0.294 0.705
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.294 0.705
M07.2 Psoriatic spondylitis
0.000 0.294 0.705
M07.1 Arthritis mutilans
0.000 0.294 0.705
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.294 0.705
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.295 0.705
G81 Hemiplegia
0.000 0.296 0.704
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.296 0.704
E53.1 Pyridoxine deficiency
0.000 0.297 0.703
E53.0 Riboflavin deficiency
0.000 0.297 0.703
D51 Vitamin B12 deficiency anaemia
0.000 0.298 0.702
D89.1 Cryoglobulinaemia
0.000 0.298 0.702
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.000 0.299 0.701
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.000 0.299 0.701
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.300 0.700
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.303 0.697
M02.90 Reactive arthropathy, unspecified (Multiple sites)
0.000 0.304 0.696
M62 Other disorders of muscle
0.000 0.305 0.695
H10-H13 Disorders of conjunctiva
0.000 0.305 0.695
H16.4 Corneal neovascularisation
0.000 0.306 0.694
D50.1 Sideropenic dysphagia
0.000 0.307 0.693
R31 Unspecified haematuria
0.689 0.311 0.000
M23.4 Loose body in knee
0.000 0.312 0.688
E06.4 Drug-induced thyroiditis
0.000 0.314 0.686
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.314 0.686
E06.0 Acute thyroiditis
0.000 0.314 0.686
M96.8 Other postprocedural musculoskeletal disorders
0.000 0.315 0.685
D86.1 Sarcoidosis of lymph nodes
0.000 0.317 0.683
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.318 0.682
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.000 0.318 0.682
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.319 0.681
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.000 0.319 0.680
H05.3 Deformity of orbit
0.000 0.319 0.680
M33.1 Other dermatomyositis
0.000 0.319 0.680
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)
0.000 0.320 0.680
M35.1 Other overlap syndromes
0.000 0.320 0.680
E03.1 Congenital hypothyroidism without goitre
0.000 0.320 0.679
M32 Systemic lupus erythematosus
0.000 0.321 0.679
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere
0.000 0.323 0.677
M23.49 Loose body in knee-Unspec lig/men
0.000 0.324 0.676
H46 Optic neuritis
0.000 0.324 0.676
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.324 0.676
M34.0 Progressive systemic sclerosis
0.000 0.324 0.676
D89.3 Immune reconstitution syndrome
0.000 0.325 0.675
L58 Radiodermatitis
0.000 0.326 0.674
L55 Sunburn
0.000 0.326 0.674
K52 Other non-infective gastro-enteritis and colitis
0.000 0.333 0.667
L57.5 Actinic granuloma
0.000 0.334 0.666
L57.3 Poikiloderma of Civatte
0.000 0.334 0.666
L57.2 Cutis rhomboidalis nuchae
0.000 0.334 0.666
L57.1 Actinic reticuloid
0.000 0.334 0.666
D84.9 Immunodeficiency, unspecified
0.000 0.336 0.664
G80 Infantile cerebral palsy
0.000 0.336 0.664
H01.9 Inflammation of eyelid, unspecified
0.000 0.337 0.663
H01.8 Other specified inflammation of eyelid
0.000 0.338 0.662
L21 Seborrhoeic dermatitis
0.000 0.338 0.662
M00.99 Pyogenic arthritis, unspecified (Site unspecified)
0.000 0.338 0.661
D86.3 Sarcoidosis of skin
0.000 0.339 0.661
L28 Lichen simplex chronicus and prurigo
0.000 0.340 0.660
M21.0 Valgus deformity, not elsewhere classified
0.000 0.341 0.659
G81.9 Hemiplegia, unspecified
0.000 0.342 0.658
D52 Folate deficiency anaemia
0.000 0.342 0.658
H18.5 Hereditary corneal dystrophies
0.000 0.343 0.657
M02.8 Other reactive arthropathies
0.000 0.344 0.656
M02.2 Postimmunisation arthropathy
0.000 0.344 0.656
M02.1 Postdysenteric arthropathy
0.000 0.344 0.656
M02.0 Arthropathy following intestinal bypass
0.000 0.344 0.656
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.344 0.656
H16.8 Other keratitis
0.000 0.345 0.655
D67 Hereditary factor IX deficiency
0.000 0.346 0.653
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.000 0.347 0.653
E06.1 Subacute thyroiditis
0.000 0.347 0.652
M12 Other specific arthropathies
0.000 0.348 0.652
M24.4 Recurrent dislocation and subluxation of joint
0.000 0.348 0.652
D53 Other nutritional anaemias
0.000 0.348 0.652
H18.7 Other corneal deformities
0.000 0.349 0.651
M00.2 Other streptococcal arthritis and polyarthritis
0.000 0.349 0.651
M00.1 Pneumococcal arthritis and polyarthritis
0.000 0.349 0.651
M00.0 Staphylococcal arthritis and polyarthritis
0.000 0.349 0.651
H05.8 Other disorders of orbit
0.000 0.350 0.650
M00.91 Pyogenic arthritis, unspecified (Shoulder region)
0.000 0.352 0.648
H05.1 Chronic inflammatory disorders of orbit
0.000 0.353 0.647
L13 Other bullous disorders
0.000 0.353 0.647
M11.8 Other specified crystal arthropathies
0.000 0.354 0.646
M11.9 Crystal arthropathy, unspecified
0.000 0.356 0.644
E06.5 Other chronic thyroiditis
0.000 0.357 0.643
L50.9 Urticaria, unspecified
0.000 0.358 0.642
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.358 0.642
L40.0 Psoriasis vulgaris
0.000 0.358 0.642
I10 Essential (primary) hypertension
0.640 0.360 0.000
D83.9 Common variable immunodeficiency, unspecified
0.000 0.360 0.640
M00.90 Pyogenic arthritis, unspecified (Multiple sites)
0.000 0.361 0.639
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.000 0.362 0.638
E61.2 Magnesium deficiency
0.000 0.362 0.638
M00.8 Arthritis and polyarthritis due to other specified bacterial agents
0.000 0.365 0.635
M24.51 Contracture of joint (Shoulder region)
0.000 0.367 0.633
M95.0 Acquired deformity of nose
0.000 0.368 0.632
H02.1 Ectropion of eyelid
0.000 0.371 0.629
L11 Other acantholytic disorders
0.000 0.371 0.629
M35.8 Other specified systemic involvement of connective tissue
0.000 0.374 0.625
H21.2 Degeneration of iris and ciliary body
0.000 0.374 0.625
M24.57 Contracture of joint (Ankle and foot)
0.000 0.375 0.625
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.377 0.623
K90.8 Other intestinal malabsorption
0.000 0.379 0.621
D84.8 Other specified immunodeficiencies
0.000 0.379 0.621
E54 Ascorbic acid deficiency
0.000 0.380 0.620
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.382 0.618
M00.98 Pyogenic arthritis, unspecified (Other)
0.000 0.383 0.616
M00.93 Pyogenic arthritis, unspecified (Forearm)
0.000 0.383 0.616
L54 Erythema in diseases classified elsewhere
0.000 0.384 0.616
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.384 0.616
D69.9 Haemorrhagic condition, unspecified
0.000 0.385 0.615
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.000 0.386 0.614
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.386 0.614
D59 Acquired haemolytic anaemia
0.000 0.387 0.613
H06.3 Other disorders of orbit in diseases classified elsewhere
0.000 0.388 0.612
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.000 0.388 0.612
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.000 0.388 0.612
L40.4 Guttate psoriasis
0.000 0.389 0.611
M02.96 Reactive arthropathy, unspecified (Lower leg)
0.000 0.390 0.610
H21.9 Disorder of iris and ciliary body, unspecified
0.000 0.390 0.610
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.391 0.609
D69.1 Qualitative platelet defects
0.000 0.391 0.609
L44 Other papulosquamous disorders
0.000 0.395 0.605
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.396 0.604
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.396 0.604
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.396 0.604
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.396 0.604
H17 Corneal scars and opacities
0.000 0.397 0.603
L42 Pityriasis rosea
0.000 0.398 0.602
L27 Dermatitis due to substances taken internally
0.000 0.398 0.602
M11.2 Other chondrocalcinosis
0.000 0.399 0.601
L40.2 Acrodermatitis continua
0.000 0.399 0.601
L57.4 Cutis laxa senilis
0.000 0.399 0.600
D82 Immunodeficiency associated with other major defects
0.000 0.400 0.600
E55.0 Rickets, active
0.000 0.400 0.600
L20 Atopic dermatitis
0.000 0.401 0.599
M49 Spondylopathies in diseases classified elsewhere
0.000 0.401 0.599
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.401 0.599
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
0.000 0.401 0.599
E56.1 Deficiency of vitamin K
0.000 0.403 0.597
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.000 0.404 0.596
H16.3 Interstitial and deep keratitis
0.000 0.404 0.596
D68 Other coagulation defects
0.000 0.404 0.596
H21.3 Cyst of iris, ciliary body and anterior chamber
0.000 0.405 0.595
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.405 0.595
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.405 0.595
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.406 0.594
M00.94 Pyogenic arthritis, unspecified (Hand)
0.000 0.406 0.594
E05.8 Other thyrotoxicosis
0.000 0.407 0.593
L40.1 Generalised pustular psoriasis
0.000 0.407 0.593
L41 Parapsoriasis
0.000 0.407 0.593
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.000 0.407 0.593
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)
0.000 0.408 0.592
K52.3 Indeterminate colitis
0.000 0.408 0.592
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.408 0.591
M24.56 Contracture of joint (Lower leg)
0.000 0.409 0.591
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.000 0.409 0.591
L28.0 Lichen simplex chronicus
0.000 0.410 0.590
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.000 0.412 0.588
L50.1 Idiopathic urticaria
0.000 0.412 0.588
M24.9 Joint derangement, unspecified
0.000 0.413 0.587
M02.38 Reiter's disease (Other)
0.000 0.414 0.585
M02.37 Reiter's disease (Ankle and foot)
0.000 0.414 0.585
M02.36 Reiter's disease (Lower leg)
0.000 0.414 0.585
M02.35 Reiter's disease (Pelvic region and thigh)
0.000 0.414 0.585
M02.34 Reiter's disease (Hand)
0.000 0.414 0.585
M02.33 Reiter's disease (Forearm)
0.000 0.414 0.585
M02.32 Reiter's disease (Upper arm)
0.000 0.414 0.585
M02.31 Reiter's disease (Shoulder region)
0.000 0.414 0.585
M02.30 Reiter's disease (Multiple sites)
0.000 0.414 0.585
M11.1 Familial chondrocalcinosis
0.000 0.415 0.585
M11.0 Hydroxyapatite deposition disease
0.000 0.415 0.585
M63 Disorders of muscle in diseases classified elsewhere
0.000 0.415 0.585
M61 Calcification and ossification of muscle
0.000 0.415 0.585
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.415 0.585
L40.3 Pustulosis palmaris et plantaris
0.000 0.415 0.585
G36.0 Neuromyelitis optica [Devic]
0.000 0.416 0.584
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)
0.000 0.416 0.584
H15 Disorders of sclera
0.000 0.416 0.583
E51.2 Wernicke's encephalopathy
0.000 0.417 0.583
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.418 0.582
M21.7 Unequal limb length (acquired)
0.000 0.419 0.580
M21.8 Other specified acquired deformities of limbs
0.000 0.420 0.579
H10 Conjunctivitis
0.000 0.421 0.579
M23.9 Internal derangement of knee, unspecified
0.000 0.421 0.578
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.422 0.578
M14 Arthropathies in other diseases classified elsewhere
0.000 0.422 0.577
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.000 0.423 0.577
H03.8 Involvement of eyelid in other diseases classified elsewhere
0.000 0.424 0.575
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere
0.000 0.424 0.575
H16.1 Other superficial keratitis without conjunctivitis
0.000 0.425 0.575
M24.2 Disorder of ligament
0.000 0.426 0.574
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.426 0.573
L13.0 Dermatitis herpetiformis
0.000 0.427 0.573
M02.99 Reactive arthropathy, unspecified (Site unspecified)
0.000 0.428 0.572
M02.98 Reactive arthropathy, unspecified (Other)
0.000 0.428 0.572
M02.97 Reactive arthropathy, unspecified (Ankle and foot)
0.000 0.428 0.572
M02.95 Reactive arthropathy, unspecified (Pelvic region and thigh)
0.000 0.428 0.572
M02.94 Reactive arthropathy, unspecified (Hand)
0.000 0.428 0.572
M02.93 Reactive arthropathy, unspecified (Forearm)
0.000 0.428 0.572
M02.92 Reactive arthropathy, unspecified (Upper arm)
0.000 0.428 0.572
M02.91 Reactive arthropathy, unspecified (Shoulder region)
0.000 0.428 0.572
M21.4 Flat foot [pes planus] (acquired)
0.000 0.429 0.571
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.429 0.570
M30.0 Polyarteritis nodosa
0.000 0.429 0.570
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.429 0.570
E40-E46 Malnutrition
0.000 0.431 0.569
M33.9 Dermatopolymyositis, unspecified
0.000 0.432 0.568
M33.0 Juvenile dermatomyositis
0.000 0.432 0.568
H05.9 Disorder of orbit, unspecified
0.000 0.433 0.567
M23.8 Other internal derangements of knee
0.000 0.434 0.566
D84.1 Defects in the complement system
0.000 0.434 0.566
D83.8 Other common variable immunodeficiencies
0.000 0.435 0.565
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.435 0.565
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.435 0.565
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.435 0.565
M60 Myositis
0.000 0.435 0.565
M00.92 Pyogenic arthritis, unspecified (Upper arm)
0.000 0.436 0.564
G80.9 Infantile cerebral palsy, unspecified
0.000 0.441 0.559
M23.41 Loose body in knee-Ant lig/hrn men
0.000 0.442 0.558
G80.2 Infantile hemiplegia
0.000 0.442 0.558
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.444 0.556
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.447 0.553
L53 Other erythematous conditions
0.000 0.447 0.553
L14 Bullous disorders in diseases classified elsewhere
0.000 0.447 0.552
M23.1 Discoid meniscus (congenital)
0.000 0.448 0.552
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.448 0.552
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.000 0.448 0.552
H16.2 Keratoconjunctivitis
0.000 0.448 0.552
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.450 0.550
L25 Unspecified contact dermatitis
0.000 0.450 0.550
E56.9 Vitamin deficiency, unspecified
0.000 0.454 0.546
E56.8 Deficiency of other vitamins
0.000 0.454 0.546
E56.0 Deficiency of vitamin E
0.000 0.454 0.546
M99 Biomechanical lesions, not elsewhere classified
0.000 0.454 0.546
M24.54 Contracture of joint (Hand)
0.000 0.457 0.543
L24 Irritant contact dermatitis
0.000 0.457 0.543
L26 Exfoliative dermatitis
0.000 0.457 0.543
L22 Diaper [napkin] dermatitis
0.000 0.457 0.543
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.000 0.458 0.542
E51.9 Thiamine deficiency, unspecified
0.000 0.459 0.541
E51.8 Other manifestations of thiamine deficiency
0.000 0.459 0.541
E51.1 Beriberi
0.000 0.459 0.541
M62.8 Other specified disorders of muscle
0.000 0.459 0.540
M08.0 Juvenile rheumatoid arthritis
0.000 0.460 0.539
M95.2 Other acquired deformity of head
0.000 0.461 0.539
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.461 0.538
H22.1 Iridocyclitis in other diseases classified elsewhere
0.000 0.463 0.537
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.000 0.463 0.537
M07.69 Other enteropathic arthropathies (Site unspecified)
0.000 0.463 0.537
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.463 0.537
M24.59 Contracture of joint (Site unspecified)
0.000 0.464 0.536
M24.58 Contracture of joint (Other)
0.000 0.464 0.536
M24.53 Contracture of joint (Forearm)
0.000 0.464 0.536
M24.50 Contracture of joint (Multiple sites)
0.000 0.464 0.536
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.465 0.535
M30.2 Juvenile polyarteritis
0.000 0.465 0.535
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere
0.000 0.465 0.535
G36.9 Acute disseminated demyelination, unspecified
0.000 0.467 0.533
G36.8 Other specified acute disseminated demyelination
0.000 0.467 0.533
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.467 0.533
L40.8 Other psoriasis
0.000 0.468 0.532
M62.6 Muscle strain
0.000 0.469 0.531
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.000 0.469 0.531
M24.52 Contracture of joint (Upper arm)
0.000 0.469 0.531
H10.9 Conjunctivitis, unspecified
0.000 0.471 0.529
L11.0 Acquired keratosis follicularis
0.000 0.472 0.528
L59.0 Erythema ab igne [dermatitis ab igne]
0.000 0.472 0.527
G37.5 Concentric sclerosis [Balo]
0.000 0.472 0.527
G37.4 Subacute necrotising myelitis
0.000 0.472 0.527
G37.2 Central pontine myelinolysis
0.000 0.472 0.527
G37.1 Central demyelination of corpus callosum
0.000 0.472 0.527
G37.0 Diffuse sclerosis
0.000 0.472 0.527
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere
0.000 0.474 0.526
H19.0 Scleritis and episcleritis in diseases classified elsewhere
0.000 0.474 0.526
Chapter XXII Codes for special purposes
0.000 0.475 0.525
D63.0 Anaemia in neoplastic disease
0.000 0.475 0.525
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.000 0.475 0.525
H57.0 Anomalies of pupillary function
0.000 0.475 0.524
H01.1 Non-infectious dermatoses of eyelid
0.000 0.476 0.524
M24.55 Contracture of joint (Pelvic region and thigh)
0.000 0.476 0.524
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.000 0.476 0.523
M36.3 Arthropathy in other blood disorders
0.000 0.476 0.523
M36.2 Haemophilic arthropathy
0.000 0.476 0.523
M36.1 Arthropathy in neoplastic disease
0.000 0.476 0.523
M36.0 Dermato(poly)myositis in neoplastic disease
0.000 0.476 0.523
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.476 0.523
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere
0.000 0.477 0.523
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere
0.000 0.477 0.523
M11.86 Other specified crystal arthropathies (Lower leg)
0.000 0.477 0.523

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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