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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2844645
log Bayes Factor = 112.248
Chromosome 6   position 31,015,182  (GRCh37) Explore rs2844645 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
L40 Psoriasis
0.000 0.001 0.999
E10.9 Without complications
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.000 0.003 0.997
M45.X9 Ankylosing spondylitis (Site unspecified)
0.989 0.011 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.014 0.986
E24 Cushing's syndrome
0.000 0.022 0.978
L40.0 Psoriasis vulgaris
0.000 0.041 0.959
D64.9 Anaemia, unspecified
0.000 0.042 0.958
E23 Hypofunction and other disorders of pituitary gland
0.000 0.054 0.946
E24.9 Cushing's syndrome, unspecified
0.000 0.066 0.934
E24.0 Pituitary-dependent Cushing's disease
0.000 0.097 0.903
E03.8 Other specified hypothyroidism
0.000 0.104 0.896
E14 Unspecified diabetes mellitus
0.000 0.113 0.887
E23.6 Other disorders of pituitary gland
0.000 0.144 0.856
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.144 0.856
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.144 0.856
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.145 0.855
E23.2 Diabetes insipidus
0.000 0.160 0.840
L40.1 Generalised pustular psoriasis
0.000 0.163 0.837
K90 Intestinal malabsorption
0.000 0.165 0.835
E24.2 Drug-induced Cushing's syndrome
0.000 0.165 0.835
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.168 0.832
E10.0 With coma
0.000 0.170 0.830
E10.1 With ketoacidosis
0.000 0.176 0.824
E40-E46 Malnutrition
0.000 0.177 0.822
E14.3 With ophthalmic complications
0.000 0.184 0.816
E13 Other specified diabetes mellitus
0.000 0.189 0.811
E21.3 Hyperparathyroidism, unspecified
0.000 0.205 0.795
E23.7 Disorder of pituitary gland, unspecified
0.000 0.215 0.785
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.220 0.780
E10.6 With other specified complications
0.000 0.229 0.770
M45 Ankylosing spondylitis
0.759 0.241 0.000
E10.2 With renal complications
0.000 0.245 0.755
E16 Other disorders of pancreatic internal secretion
0.000 0.247 0.753
K90.9 Intestinal malabsorption, unspecified
0.000 0.255 0.745
E31 Polyglandular dysfunction
0.000 0.266 0.734
E25 Adrenogenital disorders
0.000 0.267 0.733
E10.8 With unspecified complications
0.000 0.272 0.728
L40.8 Other psoriasis
0.000 0.275 0.725
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.721 0.279 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.280 0.720
L40.4 Guttate psoriasis
0.000 0.280 0.720
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E24.8 Other Cushing's syndrome
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.716
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.288 0.712
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.293 0.707
E32 Diseases of thymus
0.000 0.293 0.707
E30 Disorders of puberty, not elsewhere classified
0.000 0.293 0.707
E27 Other disorders of adrenal gland
0.000 0.297 0.703
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.297 0.703
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.299 0.701
E24.3 Ectopic ACTH syndrome
0.000 0.299 0.701
E24.1 Nelson's syndrome
0.000 0.299 0.701
E46 Unspecified protein-energy malnutrition
0.000 0.305 0.695
E28 Ovarian dysfunction
0.000 0.306 0.694
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.321 0.679
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.322 0.678
E23.1 Drug-induced hypopituitarism
0.000 0.322 0.678
E14.6 With other specified complications
0.000 0.322 0.678
E14.1 With ketoacidosis
0.000 0.324 0.676
E07 Other disorders of thyroid
0.000 0.329 0.671
E10.7 With multiple complications
0.000 0.338 0.662
L40.3 Pustulosis palmaris et plantaris
0.000 0.339 0.661
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.340 0.660
E10.4 With neurological complications
0.000 0.343 0.657
K90.8 Other intestinal malabsorption
0.000 0.346 0.654
E13.9 Without complications
0.000 0.347 0.653
E14.4 With neurological complications
0.000 0.358 0.642
E10.5 With peripheral circulatory complications
0.000 0.358 0.642
E14.5 With peripheral circulatory complications
0.000 0.363 0.637
E14.7 With multiple complications
0.000 0.364 0.636
E14.0 With coma
0.000 0.364 0.636
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.371 0.629
E14.8 With unspecified complications
0.000 0.373 0.627
E15 Nondiabetic hypoglycaemic coma
0.000 0.386 0.614
E13.3 With ophthalmic complications
0.000 0.386 0.614
E27.9 Disorder of adrenal gland, unspecified
0.000 0.387 0.613
E16.2 Hypoglycaemia, unspecified
0.000 0.387 0.613
E14.2 Withrenal complications
0.000 0.388 0.612
E03.1 Congenital hypothyroidism without goitre
0.000 0.391 0.609
K90.3 Pancreatic steatorrhoea
0.000 0.401 0.599
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.401 0.599
K90.1 Tropical sprue
0.000 0.401 0.599
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.407 0.593
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.410 0.590
E45 Retarded development following protein-energy malnutrition
0.000 0.410 0.590
E43 Unspecified severe protein-energy malnutrition
0.000 0.410 0.590
E42 Marasmic kwashiorkor
0.000 0.410 0.590
E41 Nutritional marasmus
0.000 0.410 0.590
E40 Kwashiorkor
0.000 0.410 0.590
E23.0 Hypopituitarism
0.000 0.411 0.589
E20 Hypoparathyroidism
0.000 0.415 0.584
E13.8 With unspecified complications
0.000 0.418 0.581
E13.7 With multiple complications
0.000 0.418 0.581
E13.6 With other specified complications
0.000 0.418 0.581
E13.5 With peripheral circulatory complications
0.000 0.418 0.581
E13.4 With neurological complications
0.000 0.418 0.581
E13.2 With renal complications
0.000 0.418 0.581
E13.1 With ketoacidosis
0.000 0.418 0.581
E13.0 With coma
0.000 0.418 0.581
E21.2 Other hyperparathyroidism
0.000 0.432 0.568
D64 Other anaemias
0.000 0.435 0.564
E16.1 Other hypoglycaemia
0.000 0.438 0.562
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.442 0.558
E31.0 Autoimmune polyglandular failure
0.000 0.446 0.554
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.449 0.551
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.544 0.456 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.544 0.456 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.544 0.456 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.544 0.456 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.544 0.456 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.544 0.456 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.460 0.540
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.460 0.540
E16.4 Abnormal secretion of gastrin
0.000 0.460 0.540
E16.3 Increased secretion of glucagon
0.000 0.460 0.540
E07.8 Other specified disorders of thyroid
0.000 0.468 0.532
E31.9 Polyglandular dysfunction, unspecified
0.000 0.473 0.527
E31.8 Other polyglandular dysfunction
0.000 0.473 0.527
E31.1 Polyglandular hyperfunction
0.000 0.473 0.527
E25.9 Adrenogenital disorder, unspecified
0.000 0.475 0.525
E25.8 Other adrenogenital disorders
0.000 0.475 0.525
E21.4 Other specified disorders of parathyroid gland
0.000 0.478 0.521
M45.X2 Ankylosing spondylitis (Cervical region)
0.519 0.481 0.000
E26 Hyperaldosteronism
0.000 0.481 0.519
E05.8 Other thyrotoxicosis
0.000 0.483 0.517
E14.9 Without complications
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M45.X6 Ankylosing spondylitis (Lumbar region)
0.514 0.486 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.493 0.507
E30.8 Other disorders of puberty
0.000 0.493 0.507
E30.1 Precocious puberty
0.000 0.493 0.507
E30.0 Delayed puberty
0.000 0.493 0.507
E32.9 Disease of thymus, unspecified
0.000 0.493 0.507
E32.8 Other diseases of thymus
0.000 0.493 0.507
E32.1 Abscess of thymus
0.000 0.493 0.507
E32.0 Persistent hyperplasia of thymus
0.000 0.493 0.507
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.493 0.507
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.493 0.507
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.493 0.507
E27.5 Adrenomedullary hyperfunction
0.000 0.496 0.504
E27.0 Other adrenocortical overactivity
0.000 0.496 0.504
E28.3 Primary ovarian failure
0.000 0.499 0.501
E06 Thyroiditis
0.000 0.501 0.499
E28.9 Ovarian dysfunction, unspecified
0.000 0.502 0.498
E28.8 Other ovarian dysfunction
0.000 0.502 0.498
E28.1 Androgen excess
0.000 0.502 0.498
E28.0 Oestrogen excess
0.000 0.502 0.498
E22 Hyperfunction of pituitary gland
0.000 0.518 0.482
E07.1 Dyshormogenetic goitre
0.000 0.519 0.481
E07.0 Hypersecretion of calcitonin
0.000 0.519 0.481
E28.2 Polycystic ovarian syndrome
0.000 0.519 0.481
E27.1 Primary adrenocortical insufficiency
0.000 0.520 0.480
E29 Testicular dysfunction
0.000 0.528 0.472
C61 Malignant neoplasm of prostate
0.470 0.530 0.000
E27.2 Addisonian crisis
0.000 0.536 0.464
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.542 0.458
E83.1 Disorders of iron metabolism
0.444 0.556 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.426 0.574 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.577 0.423
E44.0 Moderate protein-energy malnutrition
0.000 0.577 0.423
E20.1 Pseudohypoparathyroidism
0.000 0.581 0.419
E20.0 Idiopathic hypoparathyroidism
0.000 0.581 0.419
D64.4 Congenital dyserythropoietic anaemia
0.000 0.595 0.405
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.595 0.405
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.595 0.405
K75.4 Autoimmune hepatitis
0.000 0.606 0.394
K75 Other inflammatory liver diseases
0.000 0.608 0.392
D60-D64 Aplastic and other anaemias
0.000 0.613 0.387
D64.3 Other sideroblastic anaemias
0.000 0.619 0.381
K75.8 Other specified inflammatory liver diseases
0.000 0.619 0.381
D64.0 Hereditary sideroblastic anaemia
0.000 0.620 0.380
E20.8 Other hypoparathyroidism
0.000 0.622 0.377
E06.5 Other chronic thyroiditis
0.000 0.624 0.375
D64.8 Other specified anaemias
0.000 0.627 0.373
E26.8 Other hyperaldosteronism
0.000 0.627 0.372
E26.1 Secondary hyperaldosteronism
0.000 0.627 0.372
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.629 0.371
K70-K77 Diseases of liver
0.000 0.640 0.360
E06.4 Drug-induced thyroiditis
0.000 0.642 0.358
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.642 0.358
E06.0 Acute thyroiditis
0.000 0.642 0.358
E20.9 Hypoparathyroidism, unspecified
0.000 0.645 0.355
D62 Acute posthaemorrhagic anaemia
0.000 0.646 0.354
K73 Chronic hepatitis, not elsewhere classified
0.000 0.650 0.350
E07.9 Disorder of thyroid, unspecified
0.000 0.651 0.349
E22.8 Other hyperfunction of pituitary gland
0.000 0.654 0.346
D61 Other aplastic anaemias
0.000 0.659 0.341
E29.8 Other testicular dysfunction
0.000 0.661 0.338
E29.0 Testicular hyperfunction
0.000 0.661 0.338
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.664 0.336
E27.8 Other specified disorders of adrenal gland
0.000 0.666 0.334
E26.9 Hyperaldosteronism, unspecified
0.000 0.668 0.332
E21.0 Primary hyperparathyroidism
0.000 0.670 0.330
K72 Hepatic failure, not elsewhere classified
0.000 0.670 0.330
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.675 0.325
K72.0 Acute and subacute hepatic failure
0.000 0.685 0.315
E22.1 Hyperprolactinaemia
0.000 0.686 0.313
K73.9 Chronic hepatitis, unspecified
0.000 0.687 0.313
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.690 0.310
K75.0 Abscess of liver
0.000 0.693 0.307
D61.9 Aplastic anaemia, unspecified
0.000 0.694 0.306
E29.9 Testicular dysfunction, unspecified
0.000 0.696 0.304
E06.9 Thyroiditis, unspecified
0.000 0.696 0.304
E06.3 Autoimmune thyroiditis
0.000 0.698 0.302
E06.1 Subacute thyroiditis
0.000 0.712 0.287
K71 Toxic liver disease
0.000 0.716 0.284
K75.2 Nonspecific reactive hepatitis
0.000 0.719 0.281
K75.1 Phlebitis of portal vein
0.000 0.719 0.281
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.720 0.280
K74 Fibrosis and cirrhosis of liver
0.000 0.721 0.279
K77 Liver disorders in diseases classified elsewhere
0.000 0.742 0.258
E26.0 Primary hyperaldosteronism
0.001 0.743 0.257
K74.0 Hepatic fibrosis
0.000 0.743 0.256
E34 Other endocrine disorders
0.002 0.746 0.252
D61.0 Constitutional aplastic anaemia
0.000 0.747 0.253
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.749 0.251
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.749 0.251
D61.8 Other specified aplastic anaemias
0.000 0.755 0.245
D61.3 Idiopathic aplastic anaemia
0.000 0.755 0.245
D61.2 Aplastic anaemia due to other external agents
0.000 0.755 0.245
D61.1 Drug-induced aplastic anaemia
0.000 0.758 0.242
L40-L45 Papulosquamous disorders
0.000 0.762 0.238
K71.0 Toxic liver disease with cholestasis
0.000 0.764 0.235
E65-E68 Obesity and other hyperalimentation
0.009 0.765 0.226
I83 Varicose veins of lower extremities
0.223 0.777 0.000
K72.1 Chronic hepatic failure
0.000 0.779 0.221
K72.9 Hepatic failure, unspecified
0.000 0.783 0.217
K71.9 Toxic liver disease, unspecified
0.000 0.783 0.217
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.790 0.210
K71.8 Toxic liver disease with other disorders of liver
0.000 0.796 0.204
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.796 0.204
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.796 0.204
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.796 0.204
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.796 0.204
K71.2 Toxic liver disease with acute hepatitis
0.000 0.796 0.204
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.797 0.203
D60.8 Other acquired pure red cell aplasias
0.000 0.799 0.201
D60.1 Transient acquired pure red cell aplasia
0.000 0.799 0.201
D60.0 Chronic acquired pure red cell aplasia
0.000 0.799 0.201
K74.4 Secondary biliary cirrhosis
0.000 0.800 0.200
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.800 0.200
K74.3 Primary biliary cirrhosis
0.000 0.800 0.200
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.804 0.196
K75.9 Inflammatory liver disease, unspecified
0.000 0.807 0.193
K70 Alcoholic liver disease
0.000 0.807 0.193
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.189 0.811 0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.811 0.189
K74.1 Hepatic sclerosis
0.000 0.813 0.187
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.815 0.185
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.815 0.185
E34.5 Androgen resistance syndrome
0.001 0.818 0.181
E34.4 Constitutional tall stature
0.001 0.818 0.181
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.818 0.181
E34.1 Other hypersecretion of intestinal hormones
0.001 0.818 0.181
K74.6 Other and unspecified cirrhosis of liver
0.000 0.820 0.180
E29.1 Testicular hypofunction
0.000 0.822 0.178
I83.0 Varicose veins of lower extremities with ulcer
0.175 0.825 0.000
E50-E64 Other nutritional deficiencies
0.000 0.826 0.174
E22.0 Acromegaly and pituitary gigantism
0.001 0.826 0.173
K70.1 Alcoholic hepatitis
0.000 0.828 0.172
L44 Other papulosquamous disorders
0.000 0.829 0.171
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.829 0.171
L42 Pityriasis rosea
0.000 0.829 0.171
E67 Other hyperalimentation
0.007 0.831 0.162
E68 Sequelae of hyperalimentation
0.007 0.831 0.162
E34.3 Short stature, not elsewhere classified
0.001 0.837 0.162
K70.0 Alcoholic fatty liver
0.000 0.838 0.162
L41 Parapsoriasis
0.000 0.840 0.159
C60-C63 Malignant neoplasms of male genital organs
0.157 0.843 0.000
E83 Disorders of mineral metabolism
0.155 0.844 0.000
K76 Other diseases of liver
0.000 0.849 0.151
K76.9 Liver disease, unspecified
0.000 0.855 0.145
E34.8 Other specified endocrine disorders
0.001 0.855 0.143
E83.3 Disorders of phosphorus metabolism
0.143 0.857 0.000
K70.4 Alcoholic hepatic failure
0.000 0.857 0.143
K74.5 Biliary cirrhosis, unspecified
0.000 0.861 0.139
J47 Bronchiectasis
0.137 0.863 0.000
E51 Thiamine deficiency
0.000 0.864 0.136
C63 Malignant neoplasm of other and unspecified male genital organs
0.128 0.872 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.875 0.125
E63 Other nutritional deficiencies
0.000 0.875 0.125
E50 Vitamin A deficiency
0.000 0.875 0.125
E60 Dietary zinc deficiency
0.000 0.875 0.125
E59 Dietary selenium deficiency
0.000 0.875 0.125
E52 Niacin deficiency [pellagra]
0.000 0.875 0.125
L44.9 Papulosquamous disorder, unspecified
0.000 0.877 0.123
L44.8 Other specified papulosquamous disorders
0.000 0.877 0.123
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.877 0.123
L44.3 Lichen ruber moniliformis
0.000 0.877 0.123
L44.2 Lichen striatus
0.000 0.877 0.123
L44.1 Lichen nitidus
0.000 0.877 0.123
L44.0 Pityriasis rubra pilaris
0.000 0.877 0.123
E67.8 Other specified hyperalimentation
0.005 0.879 0.116
E67.3 Hypervitaminosis D
0.005 0.879 0.116
E67.2 Megavitamin-B6 syndrome
0.005 0.879 0.116
E67.1 Hypercarotenaemia
0.005 0.879 0.116
E67.0 Hypervitaminosis A
0.005 0.879 0.116
J98.4 Other disorders of lung
0.000 0.880 0.120
E34.0 Carcinoid syndrome
0.002 0.881 0.117
E56 Other vitamin deficiencies
0.000 0.881 0.118
L41.9 Parapsoriasis, unspecified
0.000 0.885 0.114
L41.8 Other parapsoriasis
0.000 0.885 0.114
L41.5 Retiform parapsoriasis
0.000 0.885 0.114
L41.4 Large plaque parapsoriasis
0.000 0.885 0.114
L41.3 Small plaque parapsoriasis
0.000 0.885 0.114
L41.2 Lymphomatoid papulosis
0.000 0.885 0.114
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.885 0.114
I83.1 Varicose veins of lower extremities with inflammation
0.112 0.888 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.111 0.888 0.000
E83.8 Other disorders of mineral metabolism
0.111 0.888 0.000
E83.2 Disorders of zinc metabolism
0.111 0.888 0.000
E83.0 Disorders of copper metabolism
0.111 0.888 0.000
E34.9 Endocrine disorder, unspecified
0.002 0.888 0.110
E58 Dietary calcium deficiency
0.000 0.890 0.110
K76.5 Hepatic veno-occlusive disease
0.000 0.891 0.109
K76.4 Peliosis hepatis
0.000 0.891 0.109
K76.2 Central haemorrhagic necrosis of liver
0.000 0.891 0.109
E51.2 Wernicke's encephalopathy
0.000 0.892 0.108
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.892 0.107
C60 Malignant neoplasm of penis
0.107 0.893 0.000
K76.3 Infarction of liver
0.000 0.893 0.107
C63.2 Scrotum
0.107 0.893 0.000
E54 Ascorbic acid deficiency
0.000 0.893 0.106
L43 Lichen planus
0.000 0.894 0.105
K76.1 Chronic passive congestion of liver
0.000 0.896 0.104
L41.1 Pityriasis lichenoides chronica
0.000 0.897 0.103
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.898 0.102
J98 Other respiratory disorders
0.000 0.901 0.099
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.902 0.098
E51.9 Thiamine deficiency, unspecified
0.000 0.902 0.097
E51.8 Other manifestations of thiamine deficiency
0.000 0.902 0.097
E51.1 Beriberi
0.000 0.902 0.097
K76.7 Hepatorenal syndrome
0.000 0.905 0.095
C63.9 Male genital organ, unspecified
0.092 0.908 0.000
C63.8 Overlapping lesion of male genital organs
0.092 0.908 0.000
C63.7 Other specified male genital organs
0.092 0.908 0.000
C63.1 Spermatic cord
0.092 0.908 0.000
C63.0 Epididymis
0.092 0.908 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.910 0.090
E50.8 Other manifestations of vitamin A deficiency
0.000 0.910 0.090
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.910 0.090
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.910 0.090
E50.5 Vitamin A deficiency with night blindness
0.000 0.910 0.090
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.910 0.090
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.910 0.090
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.910 0.090
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.910 0.090
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.910 0.090
E63.9 Nutritional deficiency, unspecified
0.000 0.910 0.090
E63.8 Other specified nutritional deficiencies
0.000 0.910 0.090
E63.1 Imbalance of constituents of food intake
0.000 0.910 0.090
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.910 0.090
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.910 0.090
E64.8 Sequelae of other nutritional deficiencies
0.000 0.910 0.090
E64.3 Sequelae of rickets
0.000 0.910 0.090
E64.2 Sequelae of vitamin C deficiency
0.000 0.910 0.090
E64.1 Sequelae of vitamin A deficiency
0.000 0.910 0.090
E64.0 Sequelae of protein-energy malnutrition
0.000 0.910 0.090
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.089 0.911 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.911 0.089
E55 Vitamin D deficiency
0.000 0.911 0.088
E11.1 With ketoacidosis
0.000 0.913 0.087
E56.9 Vitamin deficiency, unspecified
0.000 0.915 0.085
E56.8 Deficiency of other vitamins
0.000 0.915 0.085
E56.0 Deficiency of vitamin E
0.000 0.915 0.085
K76.0 Fatty (change of) liver, not elsewhere classified
0.000 0.915 0.085
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.084 0.916 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.083 0.917 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.083 0.917 0.000
C60.0 Prepuce
0.082 0.917 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.000 0.919 0.081
E61 Deficiency of other nutrient elements
0.000 0.919 0.080
J98.2 Interstitial emphysema
0.000 0.919 0.080
E83.4 Disorders of magnesium metabolism
0.079 0.920 0.000
E56.1 Deficiency of vitamin K
0.000 0.921 0.079
C60.8 Overlapping lesion of penis
0.077 0.923 0.000
C60.2 Body of penis
0.077 0.923 0.000
C60.1 Glans penis
0.076 0.924 0.000
L43.3 Subacute (active) lichen planus
0.000 0.924 0.076
L43.2 Lichenoid drug reaction
0.000 0.924 0.076
L43.1 Bullous lichen planus
0.000 0.924 0.076
L43.0 Hypertrophic lichen planus
0.000 0.924 0.076
J98.6 Disorders of diaphragm
0.000 0.926 0.073
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.927 0.073
J98.3 Compensatory emphysema
0.000 0.929 0.071
C62 Malignant neoplasm of testis
0.071 0.929 0.000
E65 Localised adiposity
0.010 0.931 0.059
E11.6 With other specified complications
0.000 0.934 0.066
E11.0 With coma
0.000 0.934 0.066
K90-K93 Other diseases of the digestive system
0.000 0.934 0.066
C60.9 Penis, unspecified
0.066 0.934 0.000
E04 Other non-toxic goitre
0.000 0.935 0.065
E11.7 With multiple complications
0.000 0.936 0.064
E55.0 Rickets, active
0.000 0.936 0.063
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.063 0.937 0.000
E53 Deficiency of other B group vitamins
0.000 0.938 0.062
L43.8 Other lichen planus
0.000 0.938 0.062
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.061 0.939 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.060 0.940 0.000
K70.3 Alcoholic cirrhosis of liver
0.000 0.941 0.059
E61.9 Deficiency of nutrient element, unspecified
0.000 0.942 0.058
E61.8 Deficiency of other specified nutrient elements
0.000 0.942 0.058
E61.7 Deficiency of multiple nutrient elements
0.000 0.942 0.058
E61.6 Vanadium deficiency
0.000 0.942 0.058
E61.5 Molybdenum deficiency
0.000 0.942 0.058
E61.4 Chromium deficiency
0.000 0.942 0.058
E61.3 Manganese deficiency
0.000 0.942 0.058
E61.0 Copper deficiency
0.000 0.942 0.058
J98.9 Respiratory disorder, unspecified
0.000 0.946 0.054
J98.8 Other specified respiratory disorders
0.000 0.947 0.053
E61.2 Magnesium deficiency
0.000 0.948 0.052
C62.0 Undescended testis
0.051 0.949 0.000
C62.1 Descended testis
0.049 0.951 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.047 0.952 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.952 0.047
E04.8 Other specified non-toxic goitre
0.000 0.953 0.047
E53.1 Pyridoxine deficiency
0.000 0.955 0.044
E53.0 Riboflavin deficiency
0.000 0.955 0.044
E11.8 With unspecified complications
0.000 0.955 0.045
E04.0 Non-toxic diffuse goitre
0.000 0.957 0.043
K70.9 Alcoholic liver disease, unspecified
0.000 0.959 0.041
N40 Hyperplasia of prostate
0.041 0.959 0.000
L43.9 Lichen planus, unspecified
0.000 0.959 0.041
J98.1 Pulmonary collapse
0.000 0.961 0.039
Z85.4 Personal history of malignant neoplasm of genital organs
0.036 0.964 0.000
M45-M49 Spondylopathies
0.036 0.964 0.000
E11.2 With renal complications
0.000 0.965 0.035
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.966 0.034
K93.1 Megacolon in Chagas' disease
0.000 0.966 0.034
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.966 0.034
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.966 0.034
K76.6 Portal hypertension
0.000 0.966 0.034
E11.5 With peripheral circulatory complications
0.000 0.968 0.032
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.031 0.969 0.000
E53.9 Vitamin B deficiency, unspecified
0.001 0.971 0.029
E61.1 Iron deficiency
0.000 0.973 0.027
E55.9 Vitamin D deficiency, unspecified
0.000 0.973 0.027
E66 Obesity
0.010 0.975 0.015
E70-E90 Metabolic disorders
0.018 0.975 0.007
M49 Spondylopathies in diseases classified elsewhere
0.023 0.977 0.000
S51.9 Open wound of forearm, part unspecified
0.022 0.978 0.000
R31 Unspecified haematuria
0.022 0.978 0.000
E11.3 With ophthalmic complications
0.000 0.978 0.022
S51 Open wound of forearm
0.021 0.979 0.000
E85 Amyloidosis
0.020 0.979 0.001
S51.7 Multiple open wounds of forearm
0.020 0.980 0.000
M48 Other spondylopathies
0.020 0.980 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.980 0.020
E84 Cystic fibrosis
0.015 0.981 0.004
E85.4 Organ-limited amyloidosis
0.019 0.981 0.000
E79 Disorders of purine and pyrimidine metabolism
0.014 0.981 0.004
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.019 0.981 0.000
S51.0 Open wound of elbow
0.019 0.981 0.000
E66.1 Drug-induced obesity
0.008 0.982 0.011
E83.5 Disorders of calcium metabolism
0.018 0.982 0.000
E70 Disorders of aromatic amino-acid metabolism
0.014 0.982 0.005
E72 Other disorders of amino-acid metabolism
0.014 0.982 0.005
E77 Disorders of glycoprotein metabolism
0.013 0.982 0.005
E76 Disorders of glycosaminoglycan metabolism
0.013 0.982 0.005
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.013 0.982 0.005
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.013 0.982 0.005
E85.9 Amyloidosis, unspecified
0.018 0.982 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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