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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2844650
log Bayes Factor = 38.4418
Chromosome 6   position 30,902,533  (GRCh37) Explore rs2844650 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.001 0.999
L40 Psoriasis
0.000 0.001 0.999
E11.9 Without complications
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.000 0.003 0.997
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.008 0.992
E14 Unspecified diabetes mellitus
0.000 0.018 0.982
G35-G37 Demyelinating diseases of the central nervous system
0.981 0.019 0.000
K90.0 Coeliac disease
0.000 0.031 0.969
E78.5 Hyperlipidaemia, unspecified
0.000 0.039 0.961
E14.9 Without complications
0.000 0.046 0.954
E10.1 With ketoacidosis
0.000 0.068 0.932
E10.4 With neurological complications
0.000 0.070 0.930
G37 Other demyelinating diseases of central nervous system
0.926 0.074 0.000
E11.5 With peripheral circulatory complications
0.000 0.080 0.920
Chapter VI Diseases of the nervous system
0.910 0.090 0.000
E70-E90 Metabolic disorders
0.005 0.093 0.903
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.093 0.906
E78.2 Mixed hyperlipidaemia
0.000 0.099 0.901
L40.0 Psoriasis vulgaris
0.000 0.109 0.891
E10.2 With renal complications
0.000 0.113 0.887
E11.6 With other specified complications
0.000 0.118 0.882
G37.9 Demyelinating disease of central nervous system, unspecified
0.876 0.124 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.872 0.128 0.000
E11.4 With neurological complications
0.000 0.131 0.869
E14.3 With ophthalmic complications
0.000 0.146 0.854
I24 Other acute ischaemic heart diseases
0.000 0.146 0.854
I20-I25 Ischaemic heart diseases
0.000 0.146 0.854
G40-G47 Episodic and paroxysmal disorders
0.853 0.147 0.000
G30-G32 Other degenerative diseases of the nervous system
0.837 0.163 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.164 0.836
G20-G26 Extrapyramidal and movement disorders
0.835 0.164 0.000
I21 Acute myocardial infarction
0.000 0.166 0.834
E11.0 With coma
0.000 0.175 0.825
E13 Other specified diabetes mellitus
0.000 0.179 0.821
I25 Chronic ischaemic heart disease
0.000 0.179 0.821
I24.8 Other forms of acute ischaemic heart disease
0.000 0.184 0.816
E11.1 With ketoacidosis
0.000 0.190 0.809
G40 Epilepsy
0.809 0.191 0.000
E11.2 With renal complications
0.000 0.206 0.794
I22 Subsequent myocardial infarction
0.000 0.210 0.790
E10.8 With unspecified complications
0.000 0.210 0.790
E10.5 With peripheral circulatory complications
0.000 0.215 0.785
I21.4 Acute subendocardial myocardial infarction
0.000 0.217 0.783
E78.1 Pure hyperglyceridaemia
0.000 0.223 0.777
G46 Vascular syndromes of brain in cerebrovascular diseases
0.776 0.224 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.224 0.776
I21.9 Acute myocardial infarction, unspecified
0.000 0.224 0.776
I25.1 Atherosclerotic heart disease
0.000 0.225 0.775
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.763 0.237 0.000
G20 Parkinson's disease
0.761 0.239 0.000
E10.6 With other specified complications
0.000 0.246 0.754
G43 Migraine
0.753 0.247 0.000
E78.8 Other disorders of lipoprotein metabolism
0.000 0.251 0.749
I25.2 Old myocardial infarction
0.000 0.251 0.749
G37.8 Other specified demyelinating diseases of central nervous system
0.747 0.253 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.253 0.747
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.260 0.740
E85 Amyloidosis
0.003 0.261 0.736
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.736 0.264 0.000
G03 Meningitis due to other and unspecified causes
0.733 0.267 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.731 0.269 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.720 0.280 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.280 0.720
L40.8 Other psoriasis
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.284 0.716
L40.3 Pustulosis palmaris et plantaris
0.000 0.284 0.716
L40.2 Acrodermatitis continua
0.000 0.284 0.716
L40.1 Generalised pustular psoriasis
0.000 0.284 0.716
E78.6 Lipoprotein deficiency
0.000 0.289 0.711
E78.3 Hyperchylomicronaemia
0.000 0.289 0.711
G09 Sequelae of inflammatory diseases of central nervous system
0.710 0.289 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.294 0.706
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.705 0.295 0.000
E14.8 With unspecified complications
0.000 0.296 0.704
E14.7 With multiple complications
0.000 0.296 0.704
E14.6 With other specified complications
0.000 0.296 0.704
E14.5 With peripheral circulatory complications
0.000 0.296 0.704
E14.4 With neurological complications
0.000 0.296 0.704
E14.2 Withrenal complications
0.000 0.296 0.704
E14.1 With ketoacidosis
0.000 0.296 0.704
E14.0 With coma
0.000 0.296 0.704
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.704 0.296 0.000
G36 Other acute disseminated demyelination
0.703 0.297 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.306 0.694
E13.9 Without complications
0.000 0.307 0.693
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.690 0.310 0.000
G24 Dystonia
0.683 0.317 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.317 0.683
G46.7 Other lacunar syndromes
0.675 0.325 0.000
E74 Other disorders of carbohydrate metabolism
0.003 0.330 0.667
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.330 0.670
G70-G73 Diseases of myoneural junction and muscle
0.669 0.331 0.000
G30 Alzheimer's disease
0.668 0.332 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.664 0.336 0.000
G37.5 Concentric sclerosis [Balo]
0.664 0.336 0.000
G37.4 Subacute necrotising myelitis
0.664 0.336 0.000
G37.2 Central pontine myelinolysis
0.664 0.336 0.000
G37.1 Central demyelination of corpus callosum
0.664 0.336 0.000
G37.0 Diffuse sclerosis
0.664 0.336 0.000
I25.5 Ischaemic cardiomyopathy
0.000 0.337 0.663
G46.4 Cerebellar stroke syndrome
0.657 0.343 0.000
E78.4 Other hyperlipidaemia
0.000 0.345 0.655
E83 Disorders of mineral metabolism
0.521 0.347 0.132
E79 Disorders of purine and pyrimidine metabolism
0.003 0.349 0.647
E77 Disorders of glycoprotein metabolism
0.003 0.349 0.647
E76 Disorders of glycosaminoglycan metabolism
0.003 0.349 0.647
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.003 0.349 0.647
E72 Other disorders of amino-acid metabolism
0.003 0.349 0.647
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.003 0.349 0.647
E70 Disorders of aromatic amino-acid metabolism
0.003 0.349 0.647
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.003 0.349 0.647
I23 Certain current complications following acute myocardial infarction
0.000 0.352 0.648
G43.9 Migraine, unspecified
0.643 0.357 0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.639 0.361 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.639 0.361 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.637 0.363 0.000
G31.2 Degeneration of nervous system due to alcohol
0.633 0.367 0.000
G03.9 Meningitis, unspecified
0.633 0.367 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.631 0.369 0.000
I12 Hypertensive renal disease
0.000 0.370 0.630
I10-I15 Hypertensive diseases
0.000 0.370 0.630
I10 Essential (primary) hypertension
0.000 0.372 0.628
E40-E46 Malnutrition
0.000 0.373 0.627
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.626 0.374 0.000
E73 Lactose intolerance
0.003 0.375 0.622
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.625 0.375 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.625 0.375 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.625 0.375 0.000
G43.8 Other migraine
0.623 0.377 0.000
G40.9 Epilepsy, unspecified
0.623 0.377 0.000
G00 Bacterial meningitis, not elsewhere classified
0.622 0.377 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.378 0.622
E24 Cushing's syndrome
0.000 0.380 0.620
E85.9 Amyloidosis, unspecified
0.001 0.382 0.617
G44 Other headache syndromes
0.612 0.388 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.394 0.606
G41 Status epilepticus
0.605 0.395 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.399 0.601
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.600 0.400 0.000
G23 Other degenerative diseases of basal ganglia
0.599 0.401 0.000
G21 Secondary Parkinsonism
0.599 0.401 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.599 0.401 0.000
G22 Parkinsonism in diseases classified elsewhere
0.599 0.401 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.598 0.401 0.000
E11.8 With unspecified complications
0.000 0.402 0.598
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.402 0.598
I24.1 Dressler's syndrome
0.000 0.405 0.595
E16.2 Hypoglycaemia, unspecified
0.000 0.406 0.594
E13.8 With unspecified complications
0.000 0.411 0.589
E13.7 With multiple complications
0.000 0.411 0.589
E13.6 With other specified complications
0.000 0.411 0.589
E13.5 With peripheral circulatory complications
0.000 0.411 0.589
E13.4 With neurological complications
0.000 0.411 0.589
E13.3 With ophthalmic complications
0.000 0.411 0.589
E13.2 With renal complications
0.000 0.411 0.589
E13.1 With ketoacidosis
0.000 0.411 0.589
E13.0 With coma
0.000 0.411 0.589
I25.6 Silent myocardial ischaemia
0.000 0.411 0.588
E84 Cystic fibrosis
0.004 0.412 0.585
G24.9 Dystonia, unspecified
0.585 0.415 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.004 0.415 0.581
I12.9 Hypertensive renal disease without renal failure
0.000 0.417 0.583
G06.1 Intraspinal abscess and granuloma
0.581 0.419 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.580 0.420 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.580 0.420 0.000
L40-L45 Papulosquamous disorders
0.000 0.422 0.578
G25 Other extrapyramidal and movement disorders
0.572 0.428 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.432 0.568
E22 Hyperfunction of pituitary gland
0.000 0.433 0.567
E24.9 Cushing's syndrome, unspecified
0.000 0.433 0.567
G30.8 Other Alzheimer's disease
0.563 0.437 0.000
G83 Other paralytic syndromes
0.558 0.442 0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.557 0.443 0.000
G46.6 Pure sensory lacunar syndrome
0.557 0.443 0.000
G46.5 Pure motor lacunar syndrome
0.557 0.443 0.000
G46.3 Brain stem stroke syndrome
0.557 0.443 0.000
G46.2 Posterior cerebral artery syndrome
0.557 0.443 0.000
G46.1 Anterior cerebral artery syndrome
0.557 0.443 0.000
G46.0 Middle cerebral artery syndrome
0.557 0.443 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.443 0.556
G31.1 Senile degeneration of brain, not elsewhere classified
0.547 0.453 0.000
G43.0 Migraine without aura [common migraine]
0.543 0.457 0.000
G06.2 Extradural and subdural abscess, unspecified
0.543 0.457 0.000
G24.8 Other dystonia
0.541 0.459 0.000
E29 Testicular dysfunction
0.000 0.459 0.541
G43.3 Complicated migraine
0.540 0.460 0.000
G43.2 Status migrainosus
0.540 0.460 0.000
G40.5 Special epileptic syndromes
0.539 0.461 0.000
E89.3 Postprocedural hypopituitarism
0.001 0.461 0.537
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.462 0.538
G06.0 Intracranial abscess and granuloma
0.538 0.462 0.000
G70 Myasthenia gravis and other myoneural disorders
0.536 0.464 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.469 0.530
E85.4 Organ-limited amyloidosis
0.002 0.470 0.528
E85.8 Other amyloidosis
0.002 0.470 0.528
E85.3 Secondary systemic amyloidosis
0.002 0.470 0.528
E85.2 Heredofamilial amyloidosis, unspecified
0.002 0.470 0.528
E85.1 Neuropathic heredofamilial amyloidosis
0.002 0.470 0.528
E85.0 Nonneuropathic heredofamilial amyloidosis
0.002 0.470 0.528
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.528 0.472 0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.528 0.472 0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.528 0.472 0.000
G03.8 Meningitis due to other specified causes
0.525 0.475 0.000
G03.2 Benign recurrent meningitis [Mollaret]
0.525 0.475 0.000
G03.1 Chronic meningitis
0.525 0.475 0.000
G03.0 Nonpyogenic meningitis
0.525 0.475 0.000
G43.1 Migraine with aura [classical migraine]
0.524 0.476 0.000
G82 Paraplegia and tetraplegia
0.523 0.476 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.480 0.520
G72 Other myopathies
0.519 0.481 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.484 0.516
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.515 0.485 0.000
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
I25.4 Coronary artery aneurysm
0.000 0.488 0.512
G30.0 Alzheimer's disease with early onset
0.511 0.489 0.000
I25.3 Aneurysm of heart
0.000 0.490 0.510
I15 Secondary hypertension
0.000 0.492 0.508
E50-E64 Other nutritional deficiencies
0.000 0.493 0.507
G31.0 Circumscribed brain atrophy
0.506 0.494 0.000
G44.0 Cluster headache syndrome
0.505 0.495 0.000
K90 Intestinal malabsorption
0.000 0.495 0.505
G36.9 Acute disseminated demyelination, unspecified
0.504 0.496 0.000
G36.8 Other specified acute disseminated demyelination
0.504 0.496 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.504 0.496 0.000
G36.0 Neuromyelitis optica [Devic]
0.504 0.496 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.498 0.502
I23.8 Other current complications following acute myocardial infarction
0.000 0.499 0.501
E74.3 Other disorders of intestinal carbohydrate absorption
0.002 0.500 0.498
G40.8 Other epilepsy
0.499 0.501 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.502 0.497
E32 Diseases of thymus
0.000 0.502 0.497
E31 Polyglandular dysfunction
0.000 0.502 0.497
E30 Disorders of puberty, not elsewhere classified
0.000 0.502 0.497
E25 Adrenogenital disorders
0.000 0.502 0.497
G24.4 Idiopathic orofacial dystonia
0.490 0.510 0.000
G24.3 Spasmodic torticollis
0.490 0.510 0.000
G24.2 Idiopathic nonfamilial dystonia
0.490 0.510 0.000
G24.1 Idiopathic familial dystonia
0.490 0.510 0.000
G24.0 Drug-induced dystonia
0.490 0.510 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.510 0.490
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.510 0.490
E16.4 Abnormal secretion of gastrin
0.000 0.510 0.490
E16.3 Increased secretion of glucagon
0.000 0.510 0.490
E16.1 Other hypoglycaemia
0.000 0.510 0.490
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.511 0.489
L43 Lichen planus
0.000 0.511 0.489
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.514 0.486
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.515 0.485
E28 Ovarian dysfunction
0.000 0.519 0.481
E74.9 Disorder of carbohydrate metabolism, unspecified
0.002 0.519 0.478
E74.8 Other specified disorders of carbohydrate metabolism
0.002 0.519 0.478
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.002 0.519 0.478
E74.2 Disorders of galactose metabolism
0.002 0.519 0.478
E74.1 Disorders of fructose metabolism
0.002 0.519 0.478
E74.0 Glycogen storage disease
0.002 0.519 0.478
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.479 0.520 0.000
G30.1 Alzheimer's disease with late onset
0.479 0.521 0.000
Chapter IX Diseases of the circulatory system
0.000 0.525 0.475
I22.8 Subsequent myocardial infarction of other sites
0.000 0.526 0.474
G83.4 Cauda equina syndrome
0.473 0.527 0.000
G82.1 Spastic paraplegia
0.469 0.531 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.374 0.532 0.095
E83.8 Other disorders of mineral metabolism
0.374 0.532 0.095
E83.2 Disorders of zinc metabolism
0.374 0.532 0.095
E83.0 Disorders of copper metabolism
0.374 0.532 0.095
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.003 0.533 0.464
E70.8 Other disorders of aromatic amino-acid metabolism
0.003 0.533 0.464
E70.3 Albinism
0.003 0.533 0.464
E70.2 Disorders of tyrosine metabolism
0.003 0.533 0.464
E70.1 Other hyperphenylalaninaemias
0.003 0.533 0.464
E70.0 Classical phenylketonuria
0.003 0.533 0.464
E71.3 Disorders of fatty-acid metabolism
0.003 0.533 0.464
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.003 0.533 0.464
E71.1 Other disorders of branched-chain amino-acid metabolism
0.003 0.533 0.464
E71.0 Maple-syrup-urine disease
0.003 0.533 0.464
E72.9 Disorder of amino-acid metabolism, unspecified
0.003 0.533 0.464
E72.8 Other specified disorders of amino-acid metabolism
0.003 0.533 0.464
E72.5 Disorders of glycine metabolism
0.003 0.533 0.464
E72.4 Disorders of ornithine metabolism
0.003 0.533 0.464
E72.3 Disorders of lysine and hydroxylysine metabolism
0.003 0.533 0.464
E72.2 Disorders of urea cycle metabolism
0.003 0.533 0.464
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.003 0.533 0.464
E72.0 Disorders of amino-acid transport
0.003 0.533 0.464
E75.6 Lipid storage disorder, unspecified
0.003 0.533 0.464
E75.5 Other lipid storage disorders
0.003 0.533 0.464
E75.4 Neuronal ceroid lipofuscinosis
0.003 0.533 0.464
E75.3 Sphingolipidosis, unspecified
0.003 0.533 0.464
E75.2 Other sphingolipidosis
0.003 0.533 0.464
E75.1 Other gangliosidosis
0.003 0.533 0.464
E75.0 GM2 gangliosidosis
0.003 0.533 0.464
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.003 0.533 0.464
E76.8 Other disorders of glucosaminoglycan metabolism
0.003 0.533 0.464
E76.3 Mucopolysaccharidosis, unspecified
0.003 0.533 0.464
E76.2 Other mucopolysaccharidoses
0.003 0.533 0.464
E76.1 Mucopolysaccharidosis, type II
0.003 0.533 0.464
E76.0 Mucopolysaccharidosis, type I
0.003 0.533 0.464
E77.9 Disorder of glycoprotein metabolism, unspecified
0.003 0.533 0.464
E77.8 Other disorders of glycoprotein metabolism
0.003 0.533 0.464
E77.1 Defects in glycoprotein degradation
0.003 0.533 0.464
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.003 0.533 0.464
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.003 0.533 0.464
E79.8 Other disorders of purine and pyrimidine metabolism
0.003 0.533 0.464
E79.1 Lesch-Nyhan syndrome
0.003 0.533 0.464
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.003 0.533 0.464
G10 Huntington's disease
0.466 0.534 0.000
E23.0 Hypopituitarism
0.000 0.534 0.466
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.466 0.534 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.535 0.465
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.535 0.465
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.535 0.465
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.535 0.465
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.535 0.465
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.535 0.465
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.535 0.465
E80 Disorders of porphyrin and bilirubin metabolism
0.004 0.539 0.458
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.539 0.461
G44.2 Tension-type headache
0.461 0.539 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.458 0.541 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.458 0.542 0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.456 0.543 0.000
G04.1 Tropical spastic paraplegia
0.456 0.543 0.000
G04.0 Acute disseminated encephalitis
0.456 0.543 0.000
I11 Hypertensive heart disease
0.000 0.547 0.453
G70.9 Myoneural disorder, unspecified
0.452 0.548 0.000
I13 Hypertensive heart and renal disease
0.000 0.548 0.451
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.550 0.450
E45 Retarded development following protein-energy malnutrition
0.000 0.550 0.450
E43 Unspecified severe protein-energy malnutrition
0.000 0.550 0.450
E42 Marasmic kwashiorkor
0.000 0.550 0.450
E41 Nutritional marasmus
0.000 0.550 0.450
E40 Kwashiorkor
0.000 0.550 0.450
G00.9 Bacterial meningitis, unspecified
0.450 0.550 0.000
E88 Other metabolic disorders
0.004 0.550 0.446
E73.8 Other lactose intolerance
0.003 0.552 0.446
E73.1 Secondary lactase deficiency
0.003 0.552 0.446
E73.0 Congenital lactase deficiency
0.003 0.552 0.446
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.448 0.552 0.000
G02.1 Meningitis in mycoses
0.448 0.552 0.000
G02.0 Meningitis in viral diseases classified elsewhere
0.448 0.552 0.000
G80 Infantile cerebral palsy
0.448 0.552 0.000
E20 Hypoparathyroidism
0.000 0.553 0.446
G00.8 Other bacterial meningitis
0.446 0.553 0.000
G00.3 Staphylococcal meningitis
0.446 0.553 0.000
G00.2 Streptococcal meningitis
0.446 0.553 0.000
G00.0 Haemophilus meningitis
0.446 0.553 0.000
E26 Hyperaldosteronism
0.000 0.554 0.446
E24.8 Other Cushing's syndrome
0.000 0.555 0.444
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.555 0.444
E24.3 Ectopic ACTH syndrome
0.000 0.555 0.444
E24.2 Drug-induced Cushing's syndrome
0.000 0.555 0.444
E24.1 Nelson's syndrome
0.000 0.555 0.444
E24.0 Pituitary-dependent Cushing's disease
0.000 0.555 0.444
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.557 0.443
G00.1 Pneumococcal meningitis
0.440 0.559 0.000
G44.3 Chronic posttraumatic headache
0.439 0.561 0.000
G44.1 Vascular headache, not elsewhere classified
0.439 0.561 0.000
G83.8 Other specified paralytic syndromes
0.439 0.561 0.000
L43.9 Lichen planus, unspecified
0.000 0.562 0.438
E83.5 Disorders of calcium metabolism
0.423 0.563 0.014
G41.0 Grand mal status epilepticus
0.436 0.563 0.000
G41.8 Other status epilepticus
0.434 0.566 0.000
G41.2 Complex partial status epilepticus
0.434 0.566 0.000
G41.1 Petit mal status epilepticus
0.434 0.566 0.000
E83.3 Disorders of phosphorus metabolism
0.356 0.567 0.077
E29.1 Testicular hypofunction
0.000 0.569 0.431
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.430 0.570 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.430 0.570 0.000
G21.9 Secondary Parkinsonism, unspecified
0.429 0.570 0.000
G21.8 Other secondary Parkinsonism
0.429 0.570 0.000
G21.4 Vascular parkinsonism
0.429 0.570 0.000
G21.3 Postencephalitic Parkinsonism
0.429 0.570 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.429 0.570 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.429 0.570 0.000
G21.0 Malignant neuroleptic syndrome
0.429 0.570 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.429 0.570 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.429 0.570 0.000
G23.3 Multiple system atrophy, cerebellar type
0.429 0.570 0.000
G23.2 Striatonigral degeneration
0.429 0.570 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.429 0.570 0.000
G23.0 Hallervorden-Spatz disease
0.429 0.570 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.429 0.571 0.000
G14 Postpolio syndrome
0.429 0.571 0.000
J45.9 Asthma, unspecified
0.000 0.571 0.429
G83.9 Paralytic syndrome, unspecified
0.428 0.572 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.573 0.427
G41.9 Status epilepticus, unspecified
0.425 0.575 0.000
E73.9 Lactose intolerance, unspecified
0.002 0.577 0.421
E84.8 Cystic fibrosis with other manifestations
0.003 0.578 0.419
E84.1 Cystic fibrosis with intestinal manifestations
0.003 0.578 0.419
E84.0 Cystic fibrosis with pulmonary manifestations
0.003 0.578 0.419
I15.1 Hypertension secondary to other renal disorders
0.000 0.578 0.422
G25.8 Other specified extrapyramidal and movement disorders
0.420 0.580 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.003 0.581 0.416
E89.8 Other postprocedural endocrine and metabolic disorders
0.003 0.581 0.416
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.003 0.581 0.416
E89.5 Postprocedural testicular hypofunction
0.003 0.581 0.416
E89.1 Postprocedural hypoinsulinaemia
0.003 0.581 0.416
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.581 0.418
E23.6 Other disorders of pituitary gland
0.000 0.583 0.417
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.583 0.417
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.584 0.416
E23.7 Disorder of pituitary gland, unspecified
0.000 0.585 0.415
L44 Other papulosquamous disorders
0.000 0.585 0.414
L41 Parapsoriasis
0.000 0.585 0.414
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.585 0.414
E61 Deficiency of other nutrient elements
0.000 0.588 0.412
G72.9 Myopathy, unspecified
0.411 0.589 0.000
E22.1 Hyperprolactinaemia
0.000 0.589 0.411
E23.2 Diabetes insipidus
0.000 0.589 0.411
G25.6 Drug-induced tics and other tics of organic origin
0.410 0.590 0.000
G25.5 Other chorea
0.410 0.590 0.000
G25.4 Drug-induced chorea
0.410 0.590 0.000
G25.2 Other specified forms of tremor
0.410 0.590 0.000
G25.1 Drug-induced tremor
0.410 0.590 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.592 0.408
E23.1 Drug-induced hypopituitarism
0.000 0.592 0.408
M06 Other rheumatoid arthritis
0.000 0.593 0.407
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.593 0.407
E22.8 Other hyperfunction of pituitary gland
0.000 0.593 0.407
E34 Other endocrine disorders
0.000 0.596 0.404
G83.1 Monoplegia of lower limb
0.403 0.597 0.000
G30.9 Alzheimer's disease, unspecified
0.403 0.597 0.000
G11 Hereditary ataxia
0.401 0.599 0.000
E11.3 With ophthalmic complications
0.000 0.600 0.400
G83.5 Locked-in syndrome
0.400 0.600 0.000
G83.3 Monoplegia, unspecified
0.400 0.600 0.000
G83.0 Diplegia of upper limbs
0.400 0.600 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.608 0.392
G24.5 Blepharospasm
0.391 0.609 0.000
I20 Angina pectoris
0.000 0.609 0.391
E29.9 Testicular dysfunction, unspecified
0.000 0.612 0.388
E29.8 Other testicular dysfunction
0.000 0.612 0.388
E29.0 Testicular hyperfunction
0.000 0.612 0.388
E89.2 Postprocedural hypoparathyroidism
0.003 0.612 0.385
G44.4 Drug-induced headache, not elsewhere classified
0.386 0.614 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.615 0.385
G70.8 Other specified myoneural disorders
0.384 0.616 0.000
G70.2 Congenital and developmental myasthenia
0.384 0.616 0.000
G70.1 Toxic myoneural disorders
0.384 0.616 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.619 0.381
E21.3 Hyperparathyroidism, unspecified
0.000 0.621 0.379
E28.2 Polycystic ovarian syndrome
0.000 0.624 0.376
E22.0 Acromegaly and pituitary gigantism
0.000 0.624 0.376
G82.4 Spastic tetraplegia
0.375 0.624 0.000
G82.3 Flaccid tetraplegia
0.375 0.624 0.000
G82.0 Flaccid paraplegia
0.375 0.624 0.000
L42 Pityriasis rosea
0.000 0.624 0.375
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.627 0.373
G72.8 Other specified myopathies
0.372 0.628 0.000
G72.4 Inflammatory myopathy, not elsewhere classified
0.372 0.628 0.000
G72.3 Periodic paralysis
0.372 0.628 0.000
G72.2 Myopathy due to other toxic agents
0.372 0.628 0.000
G72.1 Alcoholic myopathy
0.372 0.628 0.000
G72.0 Drug-induced myopathy
0.372 0.628 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.628 0.372
G44.8 Other specified headache syndromes
0.369 0.631 0.000
G25.3 Myoclonus
0.366 0.634 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.635 0.365
I15.9 Seconday hypertension, unspecified
0.000 0.635 0.365
I15.8 Other secondary hypertension
0.000 0.635 0.365
I15.2 Hypertension secondary to endocrine disorders
0.000 0.635 0.365
I15.0 Renovascular hypertension
0.000 0.635 0.365
G70.0 Myasthenia gravis
0.364 0.636 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.636 0.364
E63 Other nutritional deficiencies
0.000 0.636 0.364
E56 Other vitamin deficiencies
0.000 0.636 0.364
E51 Thiamine deficiency
0.000 0.636 0.364
E50 Vitamin A deficiency
0.000 0.636 0.364
E60 Dietary zinc deficiency
0.000 0.636 0.364
E59 Dietary selenium deficiency
0.000 0.636 0.364
E58 Dietary calcium deficiency
0.000 0.636 0.364
E54 Ascorbic acid deficiency
0.000 0.636 0.364
E52 Niacin deficiency [pellagra]
0.000 0.636 0.364
E89.4 Postprocedural ovarian failure
0.003 0.637 0.360
K90.8 Other intestinal malabsorption
0.000 0.638 0.362
K90.3 Pancreatic steatorrhoea
0.000 0.638 0.362
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.638 0.362
K90.1 Tropical sprue
0.000 0.638 0.362
E84.9 Cystic fibrosis, unspecified
0.003 0.640 0.356

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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