TreeWAS – Variant ID: rs2844651

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	0.999	0.001	0.000
L40.9 Psoriasis, unspecified	0.000	0.016	0.984
E06 Thyroiditis	0.949	0.051	0.000
L40 Psoriasis	0.000	0.071	0.929
L40.5 Arthropathic psoriasis	0.000	0.082	0.918
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.085	0.915
Chapter IV Endocrine, nutritional and metabolic diseases	0.875	0.125	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.871	0.129	0.000
E06.3 Autoimmune thyroiditis	0.866	0.134	0.000
E03.8 Other specified hypothyroidism	0.824	0.176	0.000
E83 Disorders of mineral metabolism	0.822	0.178	0.000
E20-E35 Disorders of other endocrine glands	0.820	0.180	0.000
E27 Other disorders of adrenal gland	0.819	0.181	0.000
E27.1 Primary adrenocortical insufficiency	0.818	0.182	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.815	0.185	0.000
E06.9 Thyroiditis, unspecified	0.814	0.186	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.806	0.194	0.000
E70-E90 Metabolic disorders	0.800	0.200	0.000
L40.0 Psoriasis vulgaris	0.000	0.213	0.787
E16 Other disorders of pancreatic internal secretion	0.756	0.244	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.756	0.244	0.000
E16.2 Hypoglycaemia, unspecified	0.738	0.262	0.000
E03.1 Congenital hypothyroidism without goitre	0.736	0.264	0.000
E06.5 Other chronic thyroiditis	0.720	0.280	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.706	0.294	0.000
E50-E64 Other nutritional deficiencies	0.705	0.295	0.000
L40.1 Generalised pustular psoriasis	0.000	0.301	0.699
E05.8 Other thyrotoxicosis	0.690	0.310	0.000
E29 Testicular dysfunction	0.689	0.311	0.000
E06.4 Drug-induced thyroiditis	0.680	0.320	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.680	0.320	0.000
E06.0 Acute thyroiditis	0.680	0.320	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.675	0.325	0.000
E06.1 Subacute thyroiditis	0.670	0.330	0.000
L40.2 Acrodermatitis continua	0.000	0.334	0.666
E31 Polyglandular dysfunction	0.649	0.351	0.000
E07 Other disorders of thyroid	0.649	0.351	0.000
E27.8 Other specified disorders of adrenal gland	0.643	0.357	0.000
E88 Other metabolic disorders	0.632	0.368	0.000
E61 Deficiency of other nutrient elements	0.631	0.369	0.000
E25 Adrenogenital disorders	0.617	0.383	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.616	0.384	0.000
E20 Hypoparathyroidism	0.605	0.395	0.000
L40.4 Guttate psoriasis	0.000	0.402	0.597
L40.8 Other psoriasis	0.000	0.403	0.597
E84 Cystic fibrosis	0.597	0.403	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.596	0.404	0.000
E73 Lactose intolerance	0.592	0.408	0.000
E83.8 Other disorders of mineral metabolism	0.589	0.411	0.000
E83.2 Disorders of zinc metabolism	0.589	0.411	0.000
E83.0 Disorders of copper metabolism	0.589	0.411	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.588	0.412	0.000
E32 Diseases of thymus	0.588	0.412	0.000
E30 Disorders of puberty, not elsewhere classified	0.588	0.412	0.000
E27.5 Adrenomedullary hyperfunction	0.587	0.413	0.000
E27.0 Other adrenocortical overactivity	0.587	0.413	0.000
E29.1 Testicular hypofunction	0.587	0.413	0.000
K90 Intestinal malabsorption	0.587	0.413	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.581	0.419	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.580	0.420	0.000
E15 Nondiabetic hypoglycaemic coma	0.578	0.422	0.000
E77 Disorders of glycoprotein metabolism	0.574	0.426	0.000
E76 Disorders of glycosaminoglycan metabolism	0.574	0.426	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.574	0.426	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.574	0.426	0.000
E72 Other disorders of amino-acid metabolism	0.570	0.430	0.000
E61.2 Magnesium deficiency	0.567	0.433	0.000
E70 Disorders of aromatic amino-acid metabolism	0.566	0.434	0.000
E74 Other disorders of carbohydrate metabolism	0.561	0.439	0.000
E79 Disorders of purine and pyrimidine metabolism	0.548	0.452	0.000
E27.2 Addisonian crisis	0.545	0.455	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.542	0.458	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.542	0.458	0.000
E16.4 Abnormal secretion of gastrin	0.542	0.458	0.000
E16.3 Increased secretion of glucagon	0.542	0.458	0.000
L40.3 Pustulosis palmaris et plantaris	0.000	0.464	0.536
K90.9 Intestinal malabsorption, unspecified	0.528	0.472	0.000
E31.0 Autoimmune polyglandular failure	0.526	0.474	0.000
E51 Thiamine deficiency	0.526	0.474	0.000
E40-E46 Malnutrition	0.522	0.478	0.000
E34 Other endocrine disorders	0.522	0.478	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.519	0.481	0.000
E58 Dietary calcium deficiency	0.517	0.483	0.000
E63 Other nutritional deficiencies	0.516	0.484	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
E29.9 Testicular dysfunction, unspecified	0.510	0.490	0.000
E26 Hyperaldosteronism	0.509	0.491	0.000
E27.9 Disorder of adrenal gland, unspecified	0.507	0.493	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.506	0.494	0.000
E50 Vitamin A deficiency	0.506	0.494	0.000
E60 Dietary zinc deficiency	0.506	0.494	0.000
E59 Dietary selenium deficiency	0.506	0.494	0.000
E54 Ascorbic acid deficiency	0.506	0.494	0.000
E52 Niacin deficiency [pellagra]	0.506	0.494	0.000
E88.9 Metabolic disorder, unspecified	0.497	0.503	0.000
E29.8 Other testicular dysfunction	0.494	0.506	0.000
E29.0 Testicular hyperfunction	0.494	0.506	0.000
E88.8 Other specified metabolic disorders	0.492	0.507	0.000
M45 Ankylosing spondylitis	0.000	0.511	0.489
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.514	0.486
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.514	0.486
E83.5 Disorders of calcium metabolism	0.483	0.517	0.000
E75.5 Other lipid storage disorders	0.483	0.517	0.000
E83.4 Disorders of magnesium metabolism	0.483	0.517	0.000
E61.1 Iron deficiency	0.479	0.520	0.000
E16.1 Other hypoglycaemia	0.472	0.527	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.471	0.529	0.000
E53 Deficiency of other B group vitamins	0.471	0.529	0.000
E24 Cushing's syndrome	0.467	0.533	0.000
E31.9 Polyglandular dysfunction, unspecified	0.465	0.535	0.000
E31.8 Other polyglandular dysfunction	0.465	0.535	0.000
E31.1 Polyglandular hyperfunction	0.465	0.535	0.000
E07.1 Dyshormogenetic goitre	0.465	0.535	0.000
E07.0 Hypersecretion of calcitonin	0.465	0.535	0.000
E07.9 Disorder of thyroid, unspecified	0.464	0.536	0.000
E89.0 Postprocedural hypothyroidism	0.463	0.537	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.539	0.461
E88.1 Lipodystrophy, not elsewhere classified	0.458	0.542	0.000
E61.9 Deficiency of nutrient element, unspecified	0.452	0.548	0.000
E61.8 Deficiency of other specified nutrient elements	0.452	0.548	0.000
E61.7 Deficiency of multiple nutrient elements	0.452	0.548	0.000
E61.6 Vanadium deficiency	0.452	0.548	0.000
E61.5 Molybdenum deficiency	0.452	0.548	0.000
E61.4 Chromium deficiency	0.452	0.548	0.000
E61.3 Manganese deficiency	0.452	0.548	0.000
E61.0 Copper deficiency	0.452	0.548	0.000
E84.9 Cystic fibrosis, unspecified	0.452	0.548	0.000
E88.2 Lipomatosis, not elsewhere classified	0.450	0.550	0.000
E88.3 Tumour lysis syndrome	0.448	0.552	0.000
E20.8 Other hypoparathyroidism	0.447	0.553	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.446	0.554	0.000
E56 Other vitamin deficiencies	0.445	0.554	0.000
E73.9 Lactose intolerance, unspecified	0.443	0.557	0.000
E25.9 Adrenogenital disorder, unspecified	0.442	0.558	0.000
E25.8 Other adrenogenital disorders	0.442	0.558	0.000
E75.6 Lipid storage disorder, unspecified	0.441	0.558	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.441	0.558	0.000
E75.3 Sphingolipidosis, unspecified	0.441	0.558	0.000
E75.2 Other sphingolipidosis	0.441	0.558	0.000
E75.1 Other gangliosidosis	0.441	0.558	0.000
E75.0 GM2 gangliosidosis	0.441	0.558	0.000
E55 Vitamin D deficiency	0.441	0.559	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.560	0.440
E20.9 Hypoparathyroidism, unspecified	0.439	0.561	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.435	0.565	0.000
E20.1 Pseudohypoparathyroidism	0.434	0.566	0.000
E20.0 Idiopathic hypoparathyroidism	0.434	0.566	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.432	0.568	0.000
E84.8 Cystic fibrosis with other manifestations	0.428	0.572	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.428	0.572	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.428	0.572	0.000
E73.8 Other lactose intolerance	0.424	0.575	0.000
E73.1 Secondary lactase deficiency	0.424	0.575	0.000
E73.0 Congenital lactase deficiency	0.424	0.575	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.578	0.422
E30.9 Disorder of puberty, unspecified	0.421	0.578	0.000
E30.8 Other disorders of puberty	0.421	0.578	0.000
E30.1 Precocious puberty	0.421	0.578	0.000
E30.0 Delayed puberty	0.421	0.578	0.000
E32.9 Disease of thymus, unspecified	0.421	0.578	0.000
E32.8 Other diseases of thymus	0.421	0.578	0.000
E32.1 Abscess of thymus	0.421	0.578	0.000
E32.0 Persistent hyperplasia of thymus	0.421	0.578	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.421	0.578	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.421	0.578	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.421	0.578	0.000
K90.3 Pancreatic steatorrhoea	0.421	0.579	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.421	0.579	0.000
K90.1 Tropical sprue	0.421	0.579	0.000
M06 Other rheumatoid arthritis	0.000	0.580	0.420
E89.2 Postprocedural hypoparathyroidism	0.419	0.581	0.000
E23 Hypofunction and other disorders of pituitary gland	0.417	0.583	0.000
M05-M14 Inflammatory polyarthropathies	0.000	0.586	0.414
E71.3 Disorders of fatty-acid metabolism	0.411	0.588	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.411	0.588	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.411	0.588	0.000
E71.0 Maple-syrup-urine disease	0.411	0.588	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.411	0.588	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.411	0.588	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.411	0.588	0.000
E76.2 Other mucopolysaccharidoses	0.411	0.588	0.000
E76.1 Mucopolysaccharidosis, type II	0.411	0.588	0.000
E76.0 Mucopolysaccharidosis, type I	0.411	0.588	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.411	0.588	0.000
E77.8 Other disorders of glycoprotein metabolism	0.411	0.588	0.000
E77.1 Defects in glycoprotein degradation	0.411	0.588	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.411	0.588	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.589	0.411
E72.9 Disorder of amino-acid metabolism, unspecified	0.408	0.591	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.408	0.591	0.000
E72.5 Disorders of glycine metabolism	0.408	0.591	0.000
E72.4 Disorders of ornithine metabolism	0.408	0.591	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.408	0.591	0.000
E72.2 Disorders of urea cycle metabolism	0.408	0.591	0.000
E72.0 Disorders of amino-acid transport	0.408	0.591	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.406	0.594	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.406	0.594	0.000
E70.2 Disorders of tyrosine metabolism	0.406	0.594	0.000
E70.1 Other hyperphenylalaninaemias	0.406	0.594	0.000
E70.0 Classical phenylketonuria	0.406	0.594	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.404	0.595	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.595	0.405
M06.3 Rheumatoid nodule	0.000	0.597	0.403
E74.9 Disorder of carbohydrate metabolism, unspecified	0.402	0.597	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.402	0.597	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.402	0.597	0.000
E74.2 Disorders of galactose metabolism	0.402	0.597	0.000
E74.1 Disorders of fructose metabolism	0.402	0.597	0.000
E28 Ovarian dysfunction	0.398	0.600	0.002
E07.8 Other specified disorders of thyroid	0.399	0.601	0.000
E70.3 Albinism	0.397	0.602	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.397	0.603	0.000
E51.2 Wernicke's encephalopathy	0.397	0.603	0.000
E34.0 Carcinoid syndrome	0.397	0.603	0.000
E74.0 Glycogen storage disease	0.395	0.604	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.393	0.607	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.393	0.607	0.000
E79.1 Lesch-Nyhan syndrome	0.393	0.607	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.607	0.393
E24.2 Drug-induced Cushing's syndrome	0.385	0.615	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.616	0.384
E63.9 Nutritional deficiency, unspecified	0.380	0.620	0.000
E51.9 Thiamine deficiency, unspecified	0.377	0.623	0.000
E51.8 Other manifestations of thiamine deficiency	0.377	0.623	0.000
E51.1 Beriberi	0.377	0.623	0.000
E22 Hyperfunction of pituitary gland	0.375	0.625	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.374	0.625	0.000
E45 Retarded development following protein-energy malnutrition	0.374	0.625	0.000
E43 Unspecified severe protein-energy malnutrition	0.374	0.625	0.000
E42 Marasmic kwashiorkor	0.374	0.625	0.000
E41 Nutritional marasmus	0.374	0.625	0.000
E40 Kwashiorkor	0.374	0.625	0.000
E34.5 Androgen resistance syndrome	0.374	0.626	0.000
E34.4 Constitutional tall stature	0.374	0.626	0.000
E34.3 Short stature, not elsewhere classified	0.374	0.626	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.374	0.626	0.000
E34.1 Other hypersecretion of intestinal hormones	0.374	0.626	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.372	0.628	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.372	0.628	0.000
E89.5 Postprocedural testicular hypofunction	0.372	0.628	0.000
E63.8 Other specified nutritional deficiencies	0.370	0.630	0.000
E63.1 Imbalance of constituents of food intake	0.370	0.630	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.370	0.630	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.632	0.368
M07 Psoriatic and enteropathic arthropathies	0.000	0.632	0.368
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.366	0.633	0.000
E26.8 Other hyperaldosteronism	0.365	0.635	0.000
E26.1 Secondary hyperaldosteronism	0.365	0.635	0.000
E50.9 Vitamin A deficiency, unspecified	0.363	0.637	0.000
E50.8 Other manifestations of vitamin A deficiency	0.363	0.637	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.363	0.637	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.363	0.637	0.000
E50.5 Vitamin A deficiency with night blindness	0.363	0.637	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.363	0.637	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.363	0.637	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.363	0.637	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.363	0.637	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.363	0.637	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.363	0.637	0.000
E64.8 Sequelae of other nutritional deficiencies	0.363	0.637	0.000
E64.3 Sequelae of rickets	0.363	0.637	0.000
E64.2 Sequelae of vitamin C deficiency	0.363	0.637	0.000
E64.1 Sequelae of vitamin A deficiency	0.363	0.637	0.000
E64.0 Sequelae of protein-energy malnutrition	0.363	0.637	0.000
E26.9 Hyperaldosteronism, unspecified	0.361	0.638	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.641	0.359
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.641	0.359
E80 Disorders of porphyrin and bilirubin metabolism	0.357	0.643	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.644	0.356
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.644	0.355
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.648	0.352
E89.1 Postprocedural hypoinsulinaemia	0.351	0.649	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.649	0.350
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.649	0.350
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.649	0.350
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.649	0.350
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.649	0.350
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.649	0.350
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.652	0.348
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.652	0.348
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.653	0.347
D86.9 Sarcoidosis, unspecified	0.347	0.653	0.000
M07.3 Other psoriatic arthropathies	0.000	0.655	0.345
E10-E14 Diabetes mellitus	0.344	0.656	0.000
E34.8 Other specified endocrine disorders	0.343	0.657	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.659	0.340
E53.9 Vitamin B deficiency, unspecified	0.339	0.661	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.661	0.339
E53.1 Pyridoxine deficiency	0.338	0.662	0.000
E53.0 Riboflavin deficiency	0.338	0.662	0.000
E89.4 Postprocedural ovarian failure	0.336	0.664	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.664	0.335
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.665	0.335
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.335	0.665	0.000
E24.3 Ectopic ACTH syndrome	0.335	0.665	0.000
E24.1 Nelson's syndrome	0.335	0.665	0.000
D86 Sarcoidosis	0.335	0.665	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.669	0.331
M06.4 Inflammatory polyarthropathy	0.000	0.670	0.330
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.671	0.329
E24.0 Pituitary-dependent Cushing's disease	0.327	0.673	0.000
E56.9 Vitamin deficiency, unspecified	0.319	0.680	0.000
E56.8 Deficiency of other vitamins	0.319	0.680	0.000
E56.0 Deficiency of vitamin E	0.319	0.680	0.000
E23.6 Other disorders of pituitary gland	0.318	0.682	0.000
E55.0 Rickets, active	0.316	0.684	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.684	0.316
M05.1 Rheumatoid lung disease	0.000	0.684	0.316
M05.0 Felty's syndrome	0.000	0.684	0.316
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.314	0.686	0.000
E34.9 Endocrine disorder, unspecified	0.314	0.686	0.000
D80-D89 Certain disorders involving the immune mechanism	0.313	0.687	0.000
M12 Other specific arthropathies	0.000	0.687	0.313
K31.7 Polyp of stomach and duodenum	0.000	0.688	0.312
M05.8 Other seropositive rheumatoid arthritis	0.000	0.691	0.309
M08 Juvenile arthritis	0.000	0.694	0.306
E24.8 Other Cushing's syndrome	0.304	0.695	0.000
E28.3 Primary ovarian failure	0.303	0.696	0.001
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.696	0.304
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.698	0.302
M06.2 Rheumatoid bursitis	0.000	0.699	0.301
M06.1 Adult-onset Still's disease	0.000	0.699	0.301
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.699	0.301
E53.8 Deficiency of other specified B group vitamins	0.301	0.699	0.000
E23.2 Diabetes insipidus	0.301	0.699	0.000
K90.8 Other intestinal malabsorption	0.299	0.700	0.000
E22.1 Hyperprolactinaemia	0.299	0.700	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.299	0.700	0.000
E23.1 Drug-induced hypopituitarism	0.299	0.700	0.000
M05.2 Rheumatoid vasculitis	0.000	0.702	0.297
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.703	0.297
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.705	0.295
E26.0 Primary hyperaldosteronism	0.292	0.707	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.291	0.709	0.000
D80 Immunodeficiency with predominantly antibody defects	0.290	0.710	0.000
D86.8 Sarcoidosis of other and combined sites	0.290	0.710	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.711	0.289
M06.38 Rheumatoid nodule (Other)	0.000	0.711	0.289
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.711	0.289
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.711	0.289
M06.33 Rheumatoid nodule (Forearm)	0.000	0.711	0.289
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.711	0.289
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.712	0.287
E28.9 Ovarian dysfunction, unspecified	0.286	0.713	0.001
E28.8 Other ovarian dysfunction	0.286	0.713	0.001
E28.1 Androgen excess	0.286	0.713	0.001
E28.0 Oestrogen excess	0.286	0.713	0.001
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.717	0.283
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.720	0.280
D86.0 Sarcoidosis of lung	0.278	0.722	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.723	0.277
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.724	0.276
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.725	0.275
E13 Other specified diabetes mellitus	0.274	0.726	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.727	0.273
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.730	0.270
E80.1 Porphyria cutanea tarda	0.270	0.730	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.730	0.270
E22.9 Hyperfunction of pituitary gland, unspecified	0.269	0.731	0.000
E22.8 Other hyperfunction of pituitary gland	0.269	0.731	0.000
E46 Unspecified protein-energy malnutrition	0.269	0.731	0.000
E44.1 Mild protein-energy malnutrition	0.268	0.731	0.000
E44.0 Moderate protein-energy malnutrition	0.268	0.731	0.000
M07.5 Arthropathy in ulcerative colitis	0.000	0.736	0.264
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.736	0.264
M07.2 Psoriatic spondylitis	0.000	0.736	0.264
M07.1 Arthritis mutilans	0.000	0.736	0.264
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.736	0.264
D86.1 Sarcoidosis of lymph nodes	0.261	0.739	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.260	0.740	0.000
E56.1 Deficiency of vitamin K	0.259	0.741	0.000
M14 Arthropathies in other diseases classified elsewhere	0.000	0.741	0.259
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.742	0.257
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.742	0.257
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.742	0.257
E80.5 Crigler-Najjar syndrome	0.256	0.744	0.000
E80.3 Defects of catalase and peroxydase	0.256	0.744	0.000
E80.0 Hereditary erythropoietic porphyria	0.256	0.744	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.744	0.256
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.744	0.256
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.254	0.745	0.001
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.253	0.746	0.000
D83 Common variable immunodeficiency	0.253	0.747	0.000
E10 Insulin-dependent diabetes mellitus	0.253	0.747	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.747	0.253
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.747	0.252
E55.9 Vitamin D deficiency, unspecified	0.252	0.748	0.000
M12.2 Villonodular synovitis (pigmented)	0.000	0.749	0.251
E65-E68 Obesity and other hyperalimentation	0.249	0.751	0.000
E21.4 Other specified disorders of parathyroid gland	0.249	0.751	0.000
E85 Amyloidosis	0.247	0.751	0.001
E21.2 Other hyperparathyroidism	0.248	0.752	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.753	0.247
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.753	0.247
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.753	0.247
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.753	0.247
E12 Malnutrition-related diabetes mellitus	0.246	0.753	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.755	0.244
E10.2 With renal complications	0.243	0.757	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.758	0.242
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.242	0.758	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.758	0.242
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.237	0.763	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.763	0.237
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.763	0.237
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.763	0.237
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.763	0.237
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.763	0.237
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.763	0.237
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.763	0.237
M12.5 Traumatic arthropathy	0.000	0.764	0.235
D84 Other immunodeficiencies	0.234	0.765	0.000
M08.0 Juvenile rheumatoid arthritis	0.000	0.771	0.229
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.228	0.772	0.000
M05.09 Felty's syndrome (Site unspecified)	0.000	0.773	0.226
M05.08 Felty's syndrome (Other)	0.000	0.773	0.226
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.773	0.226
M05.06 Felty's syndrome (Lower leg)	0.000	0.773	0.226
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.773	0.226
M05.04 Felty's syndrome (Hand)	0.000	0.773	0.226
M05.03 Felty's syndrome (Forearm)	0.000	0.773	0.226
M05.02 Felty's syndrome (Upper arm)	0.000	0.773	0.226
M05.01 Felty's syndrome (Shoulder region)	0.000	0.773	0.226
M05.00 Felty's syndrome (Multiple sites)	0.000	0.773	0.226
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.773	0.226
M05.18 Rheumatoid lung disease (Other)	0.000	0.773	0.226
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.773	0.226
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.773	0.226
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.773	0.226
M05.14 Rheumatoid lung disease (Hand)	0.000	0.773	0.226
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.773	0.226
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.773	0.226
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.773	0.226
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.773	0.226
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.773	0.226
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.773	0.226
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.773	0.226
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.773	0.226
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.773	0.226
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.773	0.226
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.773	0.226
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.773	0.226
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.773	0.226
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.773	0.226
D81 Combined immunodeficiencies	0.225	0.775	0.000
M12.4 Intermittent hydrarthrosis	0.000	0.775	0.224
M12.1 Kaschin-Beck disease	0.000	0.775	0.224
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.000	0.775	0.224
E23.0 Hypopituitarism	0.222	0.777	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.778	0.221
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.778	0.221
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.778	0.221
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.778	0.221
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.778	0.221
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.778	0.221
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.778	0.221
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.778	0.221
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.778	0.221
M07.6 Other enteropathic arthropathies	0.000	0.779	0.220
M08.9 Juvenile arthritis, unspecified	0.000	0.780	0.219
M08.8 Other juvenile arthritis	0.000	0.780	0.219
M08.4 Pauciarticular juvenile arthritis	0.000	0.780	0.219
M08.3 Juvenile polyarthritis (seronegative)	0.000	0.780	0.219
M08.2 Juvenile arthritis with systemic onset	0.000	0.780	0.219
M08.1 Juvenile ankylosing spondylitis	0.000	0.780	0.219
D82 Immunodeficiency associated with other major defects	0.218	0.782	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.783	0.217
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.784	0.216
M06.18 Adult-onset Still's disease (Other)	0.000	0.784	0.216
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.784	0.216
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.784	0.216
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.784	0.216
M06.14 Adult-onset Still's disease (Hand)	0.000	0.784	0.216
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.784	0.216
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.784	0.216
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.784	0.216
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.784	0.216

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations