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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2844669
log Bayes Factor = 78.7467
Chromosome 6   position 31,006,092  (GRCh37) Explore rs2844669 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
L40 Psoriasis
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.986 0.014 0.000
C61 Malignant neoplasm of prostate
0.968 0.032 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.036 0.964
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.038 0.962
C83.3 Large cell (diffuse)
0.000 0.040 0.960
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.040 0.960
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.041 0.959
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.041 0.959
E07 Other disorders of thyroid
0.000 0.042 0.958
C85.1 B-cell lymphoma, unspecified
0.000 0.053 0.947
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.060 0.940
E07.9 Disorder of thyroid, unspecified
0.000 0.077 0.923
E03.8 Other specified hypothyroidism
0.000 0.120 0.880
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.127 0.873
C81 Hodgkin's disease
0.000 0.132 0.868
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.162 0.838
C82.3 Follicular lymphoma grade IIIa
0.000 0.171 0.829
L40.0 Psoriasis vulgaris
0.000 0.192 0.808
C82.2 Large cell, follicular
0.000 0.192 0.808
L40.1 Generalised pustular psoriasis
0.000 0.209 0.791
C83.7 Burkitt's tumour
0.000 0.215 0.785
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.216 0.784
L40.8 Other psoriasis
0.000 0.226 0.774
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.232 0.768
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.258 0.742
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.266 0.734
C81.9 Hodgkin's disease, unspecified
0.000 0.267 0.733
E07.8 Other specified disorders of thyroid
0.000 0.271 0.729
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.291 0.708
C82.0 Small cleaved cell, follicular
0.000 0.292 0.708
C81.1 Nodular sclerosis
0.000 0.301 0.699
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.301 0.699
C85.0 Lymphosarcoma
0.000 0.309 0.691
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.310 0.690
C82.6 Cutaneous follicle centre lymphoma
0.000 0.312 0.688
C82.5 Diffuse follicle centre lymphoma
0.000 0.312 0.688
C83.6 Undifferentiated (diffuse)
0.000 0.313 0.687
C83.4 Immunoblastic (diffuse)
0.000 0.313 0.687
C83.2 Mixed small and large cell (diffuse)
0.000 0.313 0.687
E07.1 Dyshormogenetic goitre
0.000 0.313 0.687
E07.0 Hypersecretion of calcitonin
0.000 0.313 0.687
C86 Other specified types of T/NK-cell lymphoma
0.000 0.314 0.686
E06 Thyroiditis
0.000 0.315 0.685
C81.2 Mixed cellularity
0.000 0.325 0.675
C82.4 Follicular lymphoma grade IIIb
0.000 0.330 0.670
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.331 0.669
C84.5 Other and unspecified T-cell lymphomas
0.000 0.331 0.669
K90 Intestinal malabsorption
0.000 0.351 0.649
C81.0 Lymphocytic predominance
0.000 0.353 0.647
C94 Other leukaemias of specified cell type
0.000 0.354 0.646
L40.4 Guttate psoriasis
0.000 0.359 0.641
C83.5 Lymphoblastic (diffuse)
0.000 0.367 0.632
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.371 0.629
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.374 0.626
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.378 0.622
C81.3 Lymphocytic depletion
0.000 0.378 0.622
C83.1 Small cleaved cell (diffuse)
0.000 0.386 0.614
C81.7 Other Hodgkin's disease
0.000 0.387 0.613
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.389 0.611
C93 Monocytic leukaemia
0.000 0.390 0.610
C84.0 Mycosis fungoides
0.000 0.404 0.595
E05.8 Other thyrotoxicosis
0.000 0.410 0.590
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.413 0.587
E03.1 Congenital hypothyroidism without goitre
0.000 0.423 0.576
C95 Leukaemia of unspecified cell type
0.000 0.431 0.569
L40.3 Pustulosis palmaris et plantaris
0.000 0.435 0.565
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.438 0.562
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.438 0.562
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.438 0.562
C84.3 Lymphoepithelioid lymphoma
0.000 0.438 0.562
C84.2 T-zone lymphoma
0.000 0.438 0.562
C84.1 Sezary's diease
0.000 0.438 0.562
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.446 0.554
E06.3 Autoimmune thyroiditis
0.000 0.476 0.524
C88 Malignant immunoproliferative diseases
0.000 0.481 0.518
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.513
K90.9 Intestinal malabsorption, unspecified
0.000 0.503 0.497
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.505 0.495
C96.8 Histiocytic sarcoma
0.000 0.505 0.495
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.505 0.495
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.505 0.495
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.505 0.495
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.505 0.495
C96.3 True histiocytic lymphoma
0.000 0.505 0.495
C96.2 Malignant mast cell tumour
0.000 0.505 0.495
C96.1 Malignant histiocytosis
0.000 0.505 0.495
C96.0 Letterer-Siwe disease
0.000 0.505 0.495
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.508 0.492
C86.4 Blastic NK-cell lymphoma
0.000 0.508 0.492
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.508 0.492
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.508 0.492
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.508 0.492
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.508 0.492
E06.5 Other chronic thyroiditis
0.000 0.509 0.491
E06.4 Drug-induced thyroiditis
0.000 0.509 0.491
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.509 0.491
E06.0 Acute thyroiditis
0.000 0.509 0.491
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.511 0.489
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.514 0.486
K90.8 Other intestinal malabsorption
0.000 0.527 0.472
K90.3 Pancreatic steatorrhoea
0.000 0.535 0.465
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.535 0.465
K90.1 Tropical sprue
0.000 0.535 0.465
C94.7 Other specified leukaemias
0.000 0.536 0.463
C94.5 Acute myelofibrosis
0.000 0.536 0.463
C94.4 Acute panmyelosis
0.000 0.536 0.463
C94.3 Mast cell leukaemia
0.000 0.536 0.463
C94.2 Acute megakaryoblastic leukaemia
0.000 0.536 0.463
C94.1 Chronic erythraemia
0.000 0.536 0.463
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.536 0.463
E06.9 Thyroiditis, unspecified
0.000 0.541 0.459
C84.4 Peripheral T-cell lymphoma
0.000 0.542 0.458
E06.1 Subacute thyroiditis
0.000 0.546 0.453
C93.9 Monocytic leukaemia, unspecified
0.000 0.563 0.437
C93.7 Other monocytic leukaemia
0.000 0.563 0.437
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.563 0.437
C93.2 Subacute monocytic leukaemia
0.000 0.563 0.437
C93.0 Acute monocytic leukaemia
0.000 0.563 0.437
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.580 0.420
L40-L45 Papulosquamous disorders
0.000 0.582 0.418
C95.9 Leukaemia, unspecified
0.000 0.589 0.410
C95.7 Other leukaemia of unspecified cell type
0.000 0.592 0.408
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.592 0.408
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.612 0.388
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.624 0.375
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.628 0.372
C88.7 Other malignant immunoproliferative diseases
0.000 0.628 0.372
C88.3 Immunoproliferative small intestinal disease
0.000 0.628 0.372
C88.2 Gamma heavy chain disease
0.000 0.628 0.372
C88.1 Alpha heavy chain disease
0.000 0.628 0.372
C93.1 Chronic monocytic leukaemia
0.000 0.643 0.357
C60-C63 Malignant neoplasms of male genital organs
0.347 0.653 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.003 0.657 0.340
C91 Lymphoid leukaemia
0.000 0.670 0.330
L43 Lichen planus
0.000 0.684 0.316
C95.0 Acute leukaemia of unspecified cell type
0.001 0.685 0.315
L42 Pityriasis rosea
0.000 0.689 0.310
L44 Other papulosquamous disorders
0.000 0.700 0.300
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.700 0.300
C83.0 Small cell (diffuse)
0.001 0.705 0.294
C91.9 Lymphoid leukaemia, unspecified
0.000 0.708 0.292
C60 Malignant neoplasm of penis
0.275 0.725 0.000
C90.1 Plasma cell leukaemia
0.002 0.731 0.267
L41 Parapsoriasis
0.000 0.732 0.268
L43.9 Lichen planus, unspecified
0.000 0.744 0.256
C90.3 Solitary plasmacytoma
0.002 0.745 0.253
C63 Malignant neoplasm of other and unspecified male genital organs
0.254 0.746 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.763 0.237
C91.7 Other lymphoid leukaemia
0.000 0.763 0.237
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.763 0.237
C91.3 Prolymphocytic leukaemia
0.000 0.763 0.237
C91.2 Subacute lymphocytic leukaemia
0.000 0.763 0.237
C92 Myeloid leukaemia
0.001 0.768 0.231
L43.3 Subacute (active) lichen planus
0.000 0.773 0.227
L43.2 Lichenoid drug reaction
0.000 0.773 0.227
L43.1 Bullous lichen planus
0.000 0.773 0.227
L43.0 Hypertrophic lichen planus
0.000 0.773 0.227
C91.5 Adult T-cell leukaemia
0.000 0.777 0.222
L44.9 Papulosquamous disorder, unspecified
0.000 0.785 0.215
L44.8 Other specified papulosquamous disorders
0.000 0.785 0.215
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.785 0.215
L44.3 Lichen ruber moniliformis
0.000 0.785 0.215
L44.2 Lichen striatus
0.000 0.785 0.215
L44.1 Lichen nitidus
0.000 0.785 0.215
L44.0 Pityriasis rubra pilaris
0.000 0.785 0.215
C60.1 Glans penis
0.213 0.787 0.000
C60.9 Penis, unspecified
0.208 0.792 0.000
L43.8 Other lichen planus
0.000 0.793 0.207
C60.0 Prepuce
0.200 0.800 0.000
C60.8 Overlapping lesion of penis
0.197 0.803 0.000
C60.2 Body of penis
0.197 0.803 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.001 0.807 0.192
L41.9 Parapsoriasis, unspecified
0.000 0.808 0.192
L41.8 Other parapsoriasis
0.000 0.808 0.192
L41.5 Retiform parapsoriasis
0.000 0.808 0.192
L41.4 Large plaque parapsoriasis
0.000 0.808 0.192
L41.3 Small plaque parapsoriasis
0.000 0.808 0.192
L41.2 Lymphomatoid papulosis
0.000 0.808 0.192
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.808 0.192
C92.1 Chronic myeloid leukaemia
0.000 0.812 0.188
C63.2 Scrotum
0.188 0.812 0.000
C63.9 Male genital organ, unspecified
0.182 0.817 0.000
C63.8 Overlapping lesion of male genital organs
0.182 0.817 0.000
C63.7 Other specified male genital organs
0.182 0.817 0.000
C63.1 Spermatic cord
0.182 0.817 0.000
C63.0 Epididymis
0.182 0.817 0.000
C91.4 Hairy-cell leukaemia
0.000 0.831 0.169
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.168 0.832 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.001 0.833 0.166
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.001 0.833 0.166
C92.3 Myeloid sarcoma
0.001 0.833 0.166
C92.2 Subacute myeloid leukaemia
0.001 0.833 0.166
C62 Malignant neoplasm of testis
0.166 0.834 0.000
L41.1 Pityriasis lichenoides chronica
0.000 0.840 0.159
C92.5 Acute myelomonocytic leukaemia
0.001 0.844 0.155
C90.2 Plasmacytoma, extramedullary
0.003 0.849 0.148
C92.9 Myeloid leukaemia, unspecified
0.001 0.860 0.139
C91.0 Acute lymphoblastic leukaemia
0.001 0.861 0.138
C92.4 Acute promyelocytic leukaemia
0.001 0.869 0.130
C92.7 Other myeloid leukaemia
0.001 0.871 0.128
C62.0 Undescended testis
0.119 0.881 0.000
C62.1 Descended testis
0.113 0.887 0.000
E83 Disorders of mineral metabolism
0.096 0.901 0.003
E04 Other non-toxic goitre
0.000 0.918 0.082
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.922 0.078
E83.3 Disorders of phosphorus metabolism
0.074 0.925 0.001
E83.9 Disorder of mineral metabolism, unspecified
0.069 0.929 0.002
E83.8 Other disorders of mineral metabolism
0.069 0.929 0.002
E83.2 Disorders of zinc metabolism
0.069 0.929 0.002
E83.0 Disorders of copper metabolism
0.069 0.929 0.002
Z51.3 Blood transfusion without reported diagnosis
0.000 0.930 0.070
E40-E46 Malnutrition
0.000 0.932 0.068
E20-E35 Disorders of other endocrine glands
0.000 0.932 0.068
E24 Cushing's syndrome
0.000 0.933 0.067
E24.9 Cushing's syndrome, unspecified
0.000 0.937 0.063
E23 Hypofunction and other disorders of pituitary gland
0.000 0.937 0.063
E46 Unspecified protein-energy malnutrition
0.000 0.939 0.061
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.939 0.061
E21.3 Hyperparathyroidism, unspecified
0.000 0.941 0.059
E04.8 Other specified non-toxic goitre
0.000 0.941 0.059
E04.0 Non-toxic diffuse goitre
0.000 0.942 0.058
E24.0 Pituitary-dependent Cushing's disease
0.000 0.943 0.057
C91.1 Chronic lymphocytic leukaemia
0.000 0.944 0.056
E23.7 Disorder of pituitary gland, unspecified
0.000 0.944 0.056
I83 Varicose veins of lower extremities
0.055 0.945 0.000
S72 Fracture of femur
0.055 0.945 0.000
E23.2 Diabetes insipidus
0.000 0.946 0.054
E24.2 Drug-induced Cushing's syndrome
0.000 0.946 0.054
S72.1 Pertrochanteric fracture
0.053 0.947 0.000
S72.3 Fracture of shaft of femur
0.053 0.947 0.000
E28 Ovarian dysfunction
0.000 0.947 0.053
S72.10 Pertrochanteric fracture (closed)
0.052 0.948 0.000
E23.6 Other disorders of pituitary gland
0.000 0.949 0.051
C62.9 Testis, unspecified
0.051 0.949 0.000
E25 Adrenogenital disorders
0.000 0.950 0.050
S72.30 Fracture of shaft of femur (closed)
0.050 0.950 0.000
S72.9 Fracture of femur, part unspecified
0.049 0.951 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.951 0.049
E45 Retarded development following protein-energy malnutrition
0.000 0.951 0.049
E43 Unspecified severe protein-energy malnutrition
0.000 0.951 0.049
E42 Marasmic kwashiorkor
0.000 0.951 0.049
E41 Nutritional marasmus
0.000 0.951 0.049
E40 Kwashiorkor
0.000 0.951 0.049
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.951 0.049
E32 Diseases of thymus
0.000 0.951 0.049
E30 Disorders of puberty, not elsewhere classified
0.000 0.951 0.049
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.951 0.049
E24.8 Other Cushing's syndrome
0.000 0.952 0.048
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.952 0.048
E24.3 Ectopic ACTH syndrome
0.000 0.952 0.048
E24.1 Nelson's syndrome
0.000 0.952 0.048
S72.0 Fracture of neck of femur
0.048 0.952 0.000
S72.2 Subtrochanteric fracture
0.048 0.952 0.000
E31 Polyglandular dysfunction
0.000 0.952 0.048
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.953 0.047
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.954 0.046
I83.0 Varicose veins of lower extremities with ulcer
0.046 0.954 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.955 0.045
E23.1 Drug-induced hypopituitarism
0.000 0.955 0.045
S72.90 Fracture of femur, part unspecified (closed)
0.045 0.955 0.000
E28.3 Primary ovarian failure
0.000 0.955 0.045
E26 Hyperaldosteronism
0.000 0.956 0.044
S72.00 Fracture of neck of femur (closed)
0.044 0.956 0.000
S72.20 Subtrochanteric fracture (closed)
0.043 0.957 0.000
S72.31 Fracture of shaft of femur (open)
0.043 0.957 0.000
S72.8 Fractures of other parts of femur
0.042 0.958 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.042 0.958 0.000
E21.2 Other hyperparathyroidism
0.000 0.959 0.041
K90-K93 Other diseases of the digestive system
0.000 0.960 0.040
K60.2 Anal fissure, unspecified
0.000 0.960 0.040
S72.7 Multiple fractures of femur
0.040 0.960 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.961 0.038
S72.11 Pertrochanteric fracture (open)
0.038 0.962 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.962 0.038
E28.8 Other ovarian dysfunction
0.000 0.962 0.038
E28.1 Androgen excess
0.000 0.962 0.038
E28.0 Oestrogen excess
0.000 0.962 0.038
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.963 0.037
E20 Hypoparathyroidism
0.000 0.964 0.036
E25.9 Adrenogenital disorder, unspecified
0.000 0.964 0.036
E25.8 Other adrenogenital disorders
0.000 0.964 0.036
E23.0 Hypopituitarism
0.000 0.964 0.036
S72.91 Fracture of femur, part unspecified (open)
0.035 0.964 0.000
C92.0 Acute myeloid leukaemia
0.002 0.964 0.034
E44.1 Mild protein-energy malnutrition
0.000 0.965 0.035
E44.0 Moderate protein-energy malnutrition
0.000 0.965 0.035
E30.9 Disorder of puberty, unspecified
0.000 0.965 0.035
E30.8 Other disorders of puberty
0.000 0.965 0.035
E30.1 Precocious puberty
0.000 0.965 0.035
E30.0 Delayed puberty
0.000 0.965 0.035
E32.9 Disease of thymus, unspecified
0.000 0.965 0.035
E32.8 Other diseases of thymus
0.000 0.965 0.035
E32.1 Abscess of thymus
0.000 0.965 0.035
E32.0 Persistent hyperplasia of thymus
0.000 0.965 0.035
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.965 0.035
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.965 0.035
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.965 0.035
E15 Nondiabetic hypoglycaemic coma
0.000 0.965 0.035
E29 Testicular dysfunction
0.000 0.965 0.035
S72.01 Fracture of neck of femur (open)
0.035 0.965 0.000
S72.21 Subtrochanteric fracture (open)
0.035 0.965 0.000
E50-E64 Other nutritional deficiencies
0.000 0.965 0.035
E31.9 Polyglandular dysfunction, unspecified
0.000 0.966 0.034
E31.8 Other polyglandular dysfunction
0.000 0.966 0.034
E31.1 Polyglandular hyperfunction
0.000 0.966 0.034
E31.0 Autoimmune polyglandular failure
0.000 0.967 0.033
S72.80 Fractures of other parts of femur (closed)
0.033 0.967 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.967 0.033
E22 Hyperfunction of pituitary gland
0.000 0.967 0.032
E26.9 Hyperaldosteronism, unspecified
0.000 0.968 0.032
E26.8 Other hyperaldosteronism
0.000 0.968 0.032
E26.1 Secondary hyperaldosteronism
0.000 0.968 0.032
E10-E14 Diabetes mellitus
0.000 0.969 0.031
S72.4 Fracture of lower end of femur
0.031 0.969 0.000
S72.81 Fractures of other parts of femur (open)
0.030 0.969 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.971 0.029
S72.71 Multiple fractures of femur (open)
0.028 0.971 0.000
S72.70 Multiple fractures of femur (closed)
0.028 0.971 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.972 0.028
E61 Deficiency of other nutrient elements
0.000 0.972 0.028
E26.0 Primary hyperaldosteronism
0.000 0.973 0.027
E10.3 With ophthalmic complications
0.000 0.973 0.027
E10 Insulin-dependent diabetes mellitus
0.000 0.973 0.027
E51 Thiamine deficiency
0.000 0.973 0.027
E20.1 Pseudohypoparathyroidism
0.000 0.974 0.026
E20.0 Idiopathic hypoparathyroidism
0.000 0.974 0.026
E21.0 Primary hyperparathyroidism
0.000 0.974 0.026
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.974 0.025
E29.9 Testicular dysfunction, unspecified
0.000 0.974 0.025
E29.8 Other testicular dysfunction
0.000 0.974 0.025
E29.0 Testicular hyperfunction
0.000 0.974 0.025
E34 Other endocrine disorders
0.001 0.974 0.025
E56 Other vitamin deficiencies
0.000 0.975 0.025
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.975 0.025
E63 Other nutritional deficiencies
0.000 0.975 0.025
E50 Vitamin A deficiency
0.000 0.975 0.025
E60 Dietary zinc deficiency
0.000 0.975 0.025
E59 Dietary selenium deficiency
0.000 0.975 0.025
E52 Niacin deficiency [pellagra]
0.000 0.975 0.025
E83.4 Disorders of magnesium metabolism
0.023 0.975 0.002
K60 Fissure and fistula of anal and rectal regions
0.000 0.976 0.024
E58 Dietary calcium deficiency
0.000 0.976 0.024
S70-S79 Injuries to the hip and thigh
0.024 0.976 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.976 0.023
E22.8 Other hyperfunction of pituitary gland
0.000 0.976 0.023
E10.9 Without complications
0.000 0.977 0.023
E20.8 Other hypoparathyroidism
0.000 0.977 0.023
S72.41 Fracture of lower end of femur (open)
0.023 0.977 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.977 0.023
E27 Other disorders of adrenal gland
0.000 0.977 0.023
E12 Malnutrition-related diabetes mellitus
0.000 0.977 0.023
E65-E68 Obesity and other hyperalimentation
0.000 0.977 0.022
E61.2 Magnesium deficiency
0.000 0.978 0.022
K60.5 Anorectal fistula
0.000 0.978 0.022
E54 Ascorbic acid deficiency
0.000 0.979 0.021
E51.2 Wernicke's encephalopathy
0.000 0.979 0.021
E10.2 With renal complications
0.000 0.979 0.021
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.979 0.021
K93.1 Megacolon in Chagas' disease
0.000 0.979 0.021
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.979 0.021
E27.9 Disorder of adrenal gland, unspecified
0.000 0.979 0.021
E10.8 With unspecified complications
0.000 0.979 0.021
E16.1 Other hypoglycaemia
0.000 0.979 0.020
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.980 0.020
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.980 0.020
E16.4 Abnormal secretion of gastrin
0.000 0.980 0.020
E16.3 Increased secretion of glucagon
0.000 0.980 0.020
E61.1 Iron deficiency
0.000 0.980 0.020
E61.9 Deficiency of nutrient element, unspecified
0.000 0.980 0.020
E61.8 Deficiency of other specified nutrient elements
0.000 0.980 0.020
E61.7 Deficiency of multiple nutrient elements
0.000 0.980 0.020
E61.6 Vanadium deficiency
0.000 0.980 0.020
E61.5 Molybdenum deficiency
0.000 0.980 0.020
E61.4 Chromium deficiency
0.000 0.980 0.020
E61.3 Manganese deficiency
0.000 0.980 0.020
E61.0 Copper deficiency
0.000 0.980 0.020
E04.1 Non-toxic single thyroid nodule
0.000 0.980 0.020
C90.0 Multiple myeloma
0.006 0.980 0.014
E51.9 Thiamine deficiency, unspecified
0.000 0.980 0.019
E51.8 Other manifestations of thiamine deficiency
0.000 0.980 0.019
E51.1 Beriberi
0.000 0.980 0.019
S79 Other and unspecified injuries of hip and thigh
0.019 0.980 0.000
E13 Other specified diabetes mellitus
0.000 0.981 0.019
K60.0 Acute anal fissure
0.000 0.981 0.019
E34.8 Other specified endocrine disorders
0.000 0.981 0.019
E10.0 With coma
0.000 0.981 0.019
S76 Injury of muscle and tendon at hip and thigh level
0.019 0.981 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.981 0.018
E56.1 Deficiency of vitamin K
0.000 0.981 0.018
E10.7 With multiple complications
0.000 0.981 0.018
E34.5 Androgen resistance syndrome
0.001 0.981 0.018
E34.4 Constitutional tall stature
0.001 0.981 0.018
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.981 0.018
E34.1 Other hypersecretion of intestinal hormones
0.001 0.981 0.018
K60.3 Anal fistula
0.000 0.981 0.019
E56.9 Vitamin deficiency, unspecified
0.000 0.982 0.018
E56.8 Deficiency of other vitamins
0.000 0.982 0.018
E56.0 Deficiency of vitamin E
0.000 0.982 0.018
E50.9 Vitamin A deficiency, unspecified
0.000 0.982 0.018
E50.8 Other manifestations of vitamin A deficiency
0.000 0.982 0.018
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.982 0.018
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.982 0.018
E50.5 Vitamin A deficiency with night blindness
0.000 0.982 0.018
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.982 0.018
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.982 0.018
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.982 0.018
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.982 0.018
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.982 0.018
E63.9 Nutritional deficiency, unspecified
0.000 0.982 0.018
E63.8 Other specified nutritional deficiencies
0.000 0.982 0.018
E63.1 Imbalance of constituents of food intake
0.000 0.982 0.018
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.982 0.018
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.982 0.018
E64.8 Sequelae of other nutritional deficiencies
0.000 0.982 0.018
E64.3 Sequelae of rickets
0.000 0.982 0.018
E64.2 Sequelae of vitamin C deficiency
0.000 0.982 0.018
E64.1 Sequelae of vitamin A deficiency
0.000 0.982 0.018
E64.0 Sequelae of protein-energy malnutrition
0.000 0.982 0.018
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.018 0.982 0.000
E34.3 Short stature, not elsewhere classified
0.001 0.982 0.018
K60.4 Rectal fistula
0.000 0.982 0.018
E22.1 Hyperprolactinaemia
0.000 0.982 0.017
E70-E90 Metabolic disorders
0.002 0.982 0.015
E10.6 With other specified complications
0.000 0.982 0.017
E55 Vitamin D deficiency
0.000 0.983 0.017
S78 Traumatic amputation of hip and thigh
0.017 0.983 0.000
S77 Crushing injury of hip and thigh
0.017 0.983 0.000
S75 Injury of blood vessels at hip and thigh level
0.017 0.983 0.000
S74 Injury of nerves at hip and thigh level
0.017 0.983 0.000
E14 Unspecified diabetes mellitus
0.000 0.983 0.017
S79.9 Unspecified injury of hip and thigh
0.017 0.983 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.983 0.016
E27.0 Other adrenocortical overactivity
0.000 0.983 0.016
E12.9 Without complications
0.000 0.983 0.016
E12.8 With unspecified complications
0.000 0.983 0.016
E12.7 With multiple complications
0.000 0.983 0.016
E12.6 With other specified complications
0.000 0.983 0.016
E12.5 With peripheral circulatory complications
0.000 0.983 0.016
E12.4 With neurological complications
0.000 0.983 0.016
E12.3 With ophthalmic complications
0.000 0.983 0.016
E12.2 With renal complications
0.000 0.983 0.016
E12.1 With ketoacidosis
0.000 0.983 0.016
E12.0 With coma
0.000 0.983 0.016
E53 Deficiency of other B group vitamins
0.000 0.984 0.016
E67 Other hyperalimentation
0.000 0.984 0.016
E68 Sequelae of hyperalimentation
0.000 0.984 0.016
E78.0 Pure hypercholesterolaemia
0.000 0.984 0.016
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.984 0.016
S73.1 Sprain and strain of hip
0.016 0.984 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.984 0.015
S71 Open wound of hip and thigh
0.015 0.985 0.000
E89.0 Postprocedural hypothyroidism
0.000 0.985 0.015
S76.4 Injury of other and unspecified muscles and tendons at thigh level
0.015 0.985 0.000
E10.4 With neurological complications
0.000 0.985 0.015
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level
0.014 0.986 0.000
E78.8 Other disorders of lipoprotein metabolism
0.000 0.986 0.014
S79.7 Multiple injuries of hip and thigh
0.014 0.986 0.000
E13.8 With unspecified complications
0.000 0.986 0.014
E13.7 With multiple complications
0.000 0.986 0.014
E13.6 With other specified complications
0.000 0.986 0.014
E13.5 With peripheral circulatory complications
0.000 0.986 0.014
E13.4 With neurological complications
0.000 0.986 0.014
E13.3 With ophthalmic complications
0.000 0.986 0.014
E13.2 With renal complications
0.000 0.986 0.014
E13.1 With ketoacidosis
0.000 0.986 0.014
E13.0 With coma
0.000 0.986 0.014
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.986 0.014
E27.2 Addisonian crisis
0.000 0.986 0.014
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.986 0.014
S76.1 Injury of quadriceps muscle and tendon
0.014 0.986 0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level
0.014 0.986 0.000
S76.2 Injury of adductor muscle and tendon of thigh
0.014 0.986 0.000
S76.0 Injury of muscle and tendon of hip
0.014 0.986 0.000
E14.3 With ophthalmic complications
0.000 0.986 0.014
S70 Superficial injury of hip and thigh
0.014 0.986 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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