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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2844745
log Bayes Factor = 29.6095
Chromosome 6   position 30,343,703  (GRCh37) Explore rs2844745 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.047 0.953
E10 Insulin-dependent diabetes mellitus
0.000 0.078 0.922
E10.9 Without complications
0.000 0.081 0.919
E00-E07 Disorders of thyroid gland
0.000 0.091 0.909
E10.3 With ophthalmic complications
0.000 0.093 0.907
E10.2 With renal complications
0.000 0.105 0.895
E10-E14 Diabetes mellitus
0.000 0.106 0.894
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.112 0.888
K90 Intestinal malabsorption
0.000 0.152 0.848
E06 Thyroiditis
0.000 0.157 0.843
K90.9 Intestinal malabsorption, unspecified
0.000 0.222 0.778
E10.4 With neurological complications
0.000 0.223 0.777
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.245 0.755
E06.3 Autoimmune thyroiditis
0.000 0.248 0.752
E03.8 Other specified hypothyroidism
0.000 0.264 0.736
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.264 0.736
E50-E64 Other nutritional deficiencies
0.000 0.281 0.719
E06.9 Thyroiditis, unspecified
0.000 0.288 0.712
K90.8 Other intestinal malabsorption
0.000 0.313 0.687
E03.5 Myxoedema coma
0.000 0.317 0.683
E03.4 Atrophy of thyroid (acquired)
0.000 0.317 0.683
E03.3 Postinfectious hypothyroidism
0.000 0.317 0.683
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.317 0.683
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.318 0.682
E20-E35 Disorders of other endocrine glands
0.000 0.320 0.680
E14 Unspecified diabetes mellitus
0.000 0.323 0.677
E03.1 Congenital hypothyroidism without goitre
0.000 0.348 0.652
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.348 0.652
E00 Congenital iodine-deficiency syndrome
0.000 0.348 0.652
E55 Vitamin D deficiency
0.000 0.353 0.647
E12 Malnutrition-related diabetes mellitus
0.000 0.359 0.641
E10.7 With multiple complications
0.000 0.359 0.641
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.363 0.636
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.367 0.633
E13 Other specified diabetes mellitus
0.000 0.373 0.627
E16 Other disorders of pancreatic internal secretion
0.000 0.373 0.627
E06.1 Subacute thyroiditis
0.000 0.382 0.618
E22 Hyperfunction of pituitary gland
0.000 0.391 0.609
K90.3 Pancreatic steatorrhoea
0.000 0.392 0.608
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.392 0.608
K90.1 Tropical sprue
0.000 0.392 0.608
E06.5 Other chronic thyroiditis
0.000 0.395 0.605
E06.4 Drug-induced thyroiditis
0.000 0.395 0.605
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.395 0.605
E06.0 Acute thyroiditis
0.000 0.395 0.605
E27 Other disorders of adrenal gland
0.000 0.401 0.599
E55.9 Vitamin D deficiency, unspecified
0.000 0.405 0.595
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.410 0.590
E14.1 With ketoacidosis
0.000 0.413 0.587
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.425 0.575
E58 Dietary calcium deficiency
0.000 0.434 0.566
E27.1 Primary adrenocortical insufficiency
0.000 0.444 0.556
E14.4 With neurological complications
0.000 0.445 0.555
E10.0 With coma
0.000 0.451 0.549
E51 Thiamine deficiency
0.000 0.453 0.547
E10.6 With other specified complications
0.000 0.454 0.545
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.455 0.545
E05.9 Thyrotoxicosis, unspecified
0.000 0.458 0.542
E14.2 Withrenal complications
0.000 0.458 0.542
E23 Hypofunction and other disorders of pituitary gland
0.000 0.458 0.542
E21.0 Primary hyperparathyroidism
0.000 0.459 0.541
E14.8 With unspecified complications
0.000 0.465 0.535
E15 Nondiabetic hypoglycaemic coma
0.000 0.472 0.528
E22.1 Hyperprolactinaemia
0.000 0.474 0.526
E10.1 With ketoacidosis
0.000 0.483 0.517
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.484 0.515
E63 Other nutritional deficiencies
0.000 0.484 0.515
E50 Vitamin A deficiency
0.000 0.484 0.515
E60 Dietary zinc deficiency
0.000 0.484 0.515
E59 Dietary selenium deficiency
0.000 0.484 0.515
E52 Niacin deficiency [pellagra]
0.000 0.484 0.515
E10.5 With peripheral circulatory complications
0.000 0.485 0.515
E14.6 With other specified complications
0.000 0.488 0.512
E10.8 With unspecified complications
0.000 0.497 0.503
E56 Other vitamin deficiencies
0.000 0.497 0.502
E40-E46 Malnutrition
0.000 0.503 0.497
E27.2 Addisonian crisis
0.000 0.504 0.496
E54 Ascorbic acid deficiency
0.000 0.510 0.490
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.512 0.488
E32 Diseases of thymus
0.000 0.512 0.488
E31 Polyglandular dysfunction
0.000 0.512 0.488
E30 Disorders of puberty, not elsewhere classified
0.000 0.512 0.488
E14.7 With multiple complications
0.000 0.514 0.486
E14.0 With coma
0.000 0.514 0.486
E16.1 Other hypoglycaemia
0.000 0.519 0.481
E24 Cushing's syndrome
0.000 0.523 0.477
E13.3 With ophthalmic complications
0.000 0.530 0.470
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.533 0.467
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.533 0.467
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.533 0.467
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.533 0.467
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.533 0.467
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.533 0.467
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.533 0.467
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.533 0.467
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.534 0.466
E55.0 Rickets, active
0.000 0.536 0.464
E23.2 Diabetes insipidus
0.000 0.537 0.463
E12.9 Without complications
0.000 0.540 0.459
E12.8 With unspecified complications
0.000 0.540 0.459
E12.7 With multiple complications
0.000 0.540 0.459
E12.6 With other specified complications
0.000 0.540 0.459
E12.5 With peripheral circulatory complications
0.000 0.540 0.459
E12.4 With neurological complications
0.000 0.540 0.459
E12.3 With ophthalmic complications
0.000 0.540 0.459
E12.2 With renal complications
0.000 0.540 0.459
E12.1 With ketoacidosis
0.000 0.540 0.459
E12.0 With coma
0.000 0.540 0.459
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.542 0.458
E05.5 Thyroid crisis or storm
0.000 0.546 0.454
E05.4 Thyrotoxicosis factitia
0.000 0.546 0.454
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.546 0.454
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.546 0.454
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.546 0.454
E26 Hyperaldosteronism
0.000 0.547 0.453
E13.8 With unspecified complications
0.000 0.550 0.450
E13.7 With multiple complications
0.000 0.550 0.450
E13.6 With other specified complications
0.000 0.550 0.450
E13.5 With peripheral circulatory complications
0.000 0.550 0.450
E13.4 With neurological complications
0.000 0.550 0.450
E13.2 With renal complications
0.000 0.550 0.450
E13.1 With ketoacidosis
0.000 0.550 0.450
E13.0 With coma
0.000 0.550 0.450
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.550 0.449
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.550 0.449
E16.4 Abnormal secretion of gastrin
0.000 0.550 0.449
E16.3 Increased secretion of glucagon
0.000 0.550 0.449
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.563 0.437
E22.8 Other hyperfunction of pituitary gland
0.000 0.563 0.437
E27.9 Disorder of adrenal gland, unspecified
0.000 0.566 0.434
E14.3 With ophthalmic complications
0.000 0.569 0.431
E27.5 Adrenomedullary hyperfunction
0.000 0.571 0.429
E27.0 Other adrenocortical overactivity
0.000 0.571 0.429
E25 Adrenogenital disorders
0.000 0.572 0.428
E53 Deficiency of other B group vitamins
0.000 0.575 0.425
E23.0 Hypopituitarism
0.000 0.576 0.424
E51.2 Wernicke's encephalopathy
0.000 0.576 0.424
E14.5 With peripheral circulatory complications
0.000 0.581 0.419
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.587 0.413
E20 Hypoparathyroidism
0.000 0.588 0.411
E13.9 Without complications
0.000 0.588 0.411
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.591 0.409
E61 Deficiency of other nutrient elements
0.000 0.591 0.408
E21.2 Other hyperparathyroidism
0.000 0.593 0.407
E51.9 Thiamine deficiency, unspecified
0.000 0.608 0.392
E51.8 Other manifestations of thiamine deficiency
0.000 0.608 0.392
E51.1 Beriberi
0.000 0.608 0.392
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.611 0.389
E23.1 Drug-induced hypopituitarism
0.000 0.611 0.389
E23.7 Disorder of pituitary gland, unspecified
0.000 0.615 0.385
E21.4 Other specified disorders of parathyroid gland
0.000 0.620 0.380
E05.8 Other thyrotoxicosis
0.000 0.621 0.379
E07 Other disorders of thyroid
0.000 0.625 0.374
E50.9 Vitamin A deficiency, unspecified
0.000 0.630 0.370
E50.8 Other manifestations of vitamin A deficiency
0.000 0.630 0.370
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.630 0.370
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.630 0.370
E50.5 Vitamin A deficiency with night blindness
0.000 0.630 0.370
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.630 0.370
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.630 0.370
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.630 0.370
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.630 0.370
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.630 0.370
E63.9 Nutritional deficiency, unspecified
0.000 0.630 0.370
E63.8 Other specified nutritional deficiencies
0.000 0.630 0.370
E63.1 Imbalance of constituents of food intake
0.000 0.630 0.370
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.630 0.370
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.630 0.370
E64.8 Sequelae of other nutritional deficiencies
0.000 0.630 0.370
E64.3 Sequelae of rickets
0.000 0.630 0.370
E64.2 Sequelae of vitamin C deficiency
0.000 0.630 0.370
E64.1 Sequelae of vitamin A deficiency
0.000 0.630 0.370
E64.0 Sequelae of protein-energy malnutrition
0.000 0.630 0.370
E28 Ovarian dysfunction
0.000 0.634 0.366
E56.9 Vitamin deficiency, unspecified
0.000 0.639 0.360
E56.8 Deficiency of other vitamins
0.000 0.639 0.360
E56.0 Deficiency of vitamin E
0.000 0.639 0.360
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.644 0.356
E45 Retarded development following protein-energy malnutrition
0.000 0.644 0.356
E43 Unspecified severe protein-energy malnutrition
0.000 0.644 0.356
E42 Marasmic kwashiorkor
0.000 0.644 0.356
E41 Nutritional marasmus
0.000 0.644 0.356
E40 Kwashiorkor
0.000 0.644 0.356
E24.8 Other Cushing's syndrome
0.000 0.646 0.354
E30.9 Disorder of puberty, unspecified
0.000 0.650 0.350
E30.8 Other disorders of puberty
0.000 0.650 0.350
E30.1 Precocious puberty
0.000 0.650 0.350
E30.0 Delayed puberty
0.000 0.650 0.350
E31.9 Polyglandular dysfunction, unspecified
0.000 0.650 0.350
E31.8 Other polyglandular dysfunction
0.000 0.650 0.350
E31.1 Polyglandular hyperfunction
0.000 0.650 0.350
E31.0 Autoimmune polyglandular failure
0.000 0.650 0.350
E32.9 Disease of thymus, unspecified
0.000 0.650 0.350
E32.8 Other diseases of thymus
0.000 0.650 0.350
E32.1 Abscess of thymus
0.000 0.650 0.350
E32.0 Persistent hyperplasia of thymus
0.000 0.650 0.350
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.650 0.350
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.650 0.350
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.650 0.350
E56.1 Deficiency of vitamin K
0.000 0.652 0.347
E29 Testicular dysfunction
0.000 0.658 0.342
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.658 0.342
E24.3 Ectopic ACTH syndrome
0.000 0.658 0.342
E24.1 Nelson's syndrome
0.000 0.658 0.342
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.658 0.341
E24.0 Pituitary-dependent Cushing's disease
0.000 0.659 0.341
E24.2 Drug-induced Cushing's syndrome
0.000 0.665 0.335
E24.9 Cushing's syndrome, unspecified
0.000 0.673 0.327
E26.9 Hyperaldosteronism, unspecified
0.000 0.673 0.326
E21.3 Hyperparathyroidism, unspecified
0.000 0.674 0.326
E26.8 Other hyperaldosteronism
0.000 0.675 0.325
E26.1 Secondary hyperaldosteronism
0.000 0.675 0.325
E22.0 Acromegaly and pituitary gigantism
0.000 0.676 0.324
E25.9 Adrenogenital disorder, unspecified
0.000 0.693 0.307
E25.8 Other adrenogenital disorders
0.000 0.693 0.307
E53.1 Pyridoxine deficiency
0.000 0.695 0.305
E53.0 Riboflavin deficiency
0.000 0.695 0.305
E16.2 Hypoglycaemia, unspecified
0.000 0.696 0.304
E23.6 Other disorders of pituitary gland
0.000 0.702 0.297
E20.8 Other hypoparathyroidism
0.000 0.705 0.295
E20.1 Pseudohypoparathyroidism
0.000 0.705 0.295
E20.0 Idiopathic hypoparathyroidism
0.000 0.705 0.295
E61.9 Deficiency of nutrient element, unspecified
0.000 0.707 0.293
E61.8 Deficiency of other specified nutrient elements
0.000 0.707 0.293
E61.7 Deficiency of multiple nutrient elements
0.000 0.707 0.293
E61.6 Vanadium deficiency
0.000 0.707 0.293
E61.5 Molybdenum deficiency
0.000 0.707 0.293
E61.4 Chromium deficiency
0.000 0.707 0.293
E61.3 Manganese deficiency
0.000 0.707 0.293
E61.0 Copper deficiency
0.000 0.707 0.293
E26.0 Primary hyperaldosteronism
0.000 0.711 0.288
E27.8 Other specified disorders of adrenal gland
0.000 0.712 0.288
E07.1 Dyshormogenetic goitre
0.000 0.731 0.268
E07.0 Hypersecretion of calcitonin
0.000 0.731 0.268
E53.8 Deficiency of other specified B group vitamins
0.000 0.733 0.267
E53.9 Vitamin B deficiency, unspecified
0.000 0.734 0.265
E61.2 Magnesium deficiency
0.000 0.737 0.263
E28.9 Ovarian dysfunction, unspecified
0.000 0.737 0.262
E28.8 Other ovarian dysfunction
0.000 0.737 0.262
E28.1 Androgen excess
0.000 0.737 0.262
E28.0 Oestrogen excess
0.000 0.737 0.262
E44.1 Mild protein-energy malnutrition
0.000 0.744 0.255
E44.0 Moderate protein-energy malnutrition
0.000 0.744 0.255
E34 Other endocrine disorders
0.001 0.749 0.251
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.753 0.247
E29.8 Other testicular dysfunction
0.000 0.754 0.245
E29.0 Testicular hyperfunction
0.000 0.754 0.245
E07.8 Other specified disorders of thyroid
0.000 0.761 0.239
E29.9 Testicular dysfunction, unspecified
0.000 0.764 0.236
E61.1 Iron deficiency
0.000 0.768 0.232
E20.9 Hypoparathyroidism, unspecified
0.000 0.781 0.219
E28.2 Polycystic ovarian syndrome
0.000 0.783 0.217
E46 Unspecified protein-energy malnutrition
0.000 0.784 0.216
E28.3 Primary ovarian failure
0.000 0.790 0.210
E65-E68 Obesity and other hyperalimentation
0.001 0.797 0.202
E34.5 Androgen resistance syndrome
0.001 0.819 0.180
E34.4 Constitutional tall stature
0.001 0.819 0.180
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.819 0.180
E34.1 Other hypersecretion of intestinal hormones
0.001 0.819 0.180
E34.8 Other specified endocrine disorders
0.001 0.826 0.173
E34.3 Short stature, not elsewhere classified
0.001 0.828 0.171
E04 Other non-toxic goitre
0.000 0.853 0.147
E67 Other hyperalimentation
0.001 0.854 0.145
E68 Sequelae of hyperalimentation
0.001 0.854 0.145
E34.0 Carcinoid syndrome
0.001 0.857 0.142
E29.1 Testicular hypofunction
0.000 0.879 0.121
E04.0 Non-toxic diffuse goitre
0.000 0.894 0.106
E04.8 Other specified non-toxic goitre
0.000 0.894 0.106
E67.8 Other specified hyperalimentation
0.001 0.895 0.104
E67.3 Hypervitaminosis D
0.001 0.895 0.104
E67.2 Megavitamin-B6 syndrome
0.001 0.895 0.104
E67.1 Hypercarotenaemia
0.001 0.895 0.104
E67.0 Hypervitaminosis A
0.001 0.895 0.104
E34.9 Endocrine disorder, unspecified
0.001 0.911 0.088
E04.2 Non-toxic multinodular goitre
0.000 0.918 0.082
G25.8 Other specified extrapyramidal and movement disorders
0.079 0.921 0.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.921 0.079
E07.9 Disorder of thyroid, unspecified
0.000 0.925 0.075
G25 Other extrapyramidal and movement disorders
0.075 0.925 0.000
G20-G26 Extrapyramidal and movement disorders
0.072 0.928 0.000
G24 Dystonia
0.072 0.928 0.000
G24.9 Dystonia, unspecified
0.067 0.933 0.000
G21 Secondary Parkinsonism
0.064 0.936 0.000
G24.3 Spasmodic torticollis
0.062 0.938 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.062 0.938 0.000
G24.8 Other dystonia
0.059 0.941 0.000
G25.1 Drug-induced tremor
0.058 0.942 0.000
G25.5 Other chorea
0.058 0.942 0.000
G21.9 Secondary Parkinsonism, unspecified
0.056 0.944 0.000
G23 Other degenerative diseases of basal ganglia
0.056 0.944 0.000
G20 Parkinson's disease
0.055 0.945 0.000
G24.1 Idiopathic familial dystonia
0.054 0.945 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.054 0.946 0.000
G25.4 Drug-induced chorea
0.054 0.946 0.000
G24.0 Drug-induced dystonia
0.052 0.947 0.000
G25.0 Essential tremor
0.053 0.947 0.000
K90-K93 Other diseases of the digestive system
0.000 0.948 0.052
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.052 0.948 0.000
G22 Parkinsonism in diseases classified elsewhere
0.052 0.948 0.000
G24.4 Idiopathic orofacial dystonia
0.051 0.948 0.000
G24.2 Idiopathic nonfamilial dystonia
0.051 0.948 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.050 0.949 0.000
E83 Disorders of mineral metabolism
0.025 0.952 0.023
E65 Localised adiposity
0.003 0.953 0.044
G21.8 Other secondary Parkinsonism
0.046 0.954 0.000
G21.4 Vascular parkinsonism
0.046 0.954 0.000
G21.3 Postencephalitic Parkinsonism
0.046 0.954 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.046 0.954 0.000
G21.0 Malignant neuroleptic syndrome
0.046 0.954 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.046 0.954 0.000
G24.5 Blepharospasm
0.044 0.956 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.043 0.957 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.042 0.958 0.000
G25.3 Myoclonus
0.042 0.958 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.040 0.960 0.000
G23.3 Multiple system atrophy, cerebellar type
0.040 0.960 0.000
G23.2 Striatonigral degeneration
0.040 0.960 0.000
G23.0 Hallervorden-Spatz disease
0.040 0.960 0.000
G25.2 Other specified forms of tremor
0.039 0.961 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.962 0.038
E83.8 Other disorders of mineral metabolism
0.018 0.965 0.016
E83.2 Disorders of zinc metabolism
0.018 0.965 0.016
E83.0 Disorders of copper metabolism
0.018 0.965 0.016
E83.9 Disorder of mineral metabolism, unspecified
0.018 0.966 0.016
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.973 0.027
K93.1 Megacolon in Chagas' disease
0.000 0.973 0.027
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.973 0.027
E04.1 Non-toxic single thyroid nodule
0.000 0.973 0.027
E70-E90 Metabolic disorders
0.001 0.973 0.026
E83.3 Disorders of phosphorus metabolism
0.005 0.974 0.022
E04.9 Non-toxic goitre, unspecified
0.000 0.975 0.025
E66 Obesity
0.000 0.976 0.024
N05.9 Unspecified
0.000 0.976 0.024
E83.4 Disorders of magnesium metabolism
0.003 0.977 0.020
E14.9 Without complications
0.000 0.978 0.022
N05 Unspecified nephritic syndrome
0.000 0.978 0.022
N05.2 Diffuse membranous glomerulonephritis
0.000 0.980 0.020
E70 Disorders of aromatic amino-acid metabolism
0.000 0.980 0.019
E74 Other disorders of carbohydrate metabolism
0.000 0.980 0.019
N05.8 Other
0.000 0.980 0.019
E86 Volume depletion
0.000 0.981 0.019
E77 Disorders of glycoprotein metabolism
0.001 0.981 0.019
E76 Disorders of glycosaminoglycan metabolism
0.001 0.981 0.019
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.981 0.019
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.981 0.019
E72 Other disorders of amino-acid metabolism
0.000 0.981 0.019
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.981 0.019
E84 Cystic fibrosis
0.001 0.981 0.018
E79 Disorders of purine and pyrimidine metabolism
0.001 0.981 0.018
E66.0 Obesity due to excess calories
0.000 0.982 0.018
E66.1 Drug-induced obesity
0.000 0.983 0.017
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.983 0.017
E73 Lactose intolerance
0.000 0.983 0.017
N05.1 Focal and segmental glomerular lesions
0.000 0.983 0.016
K81.0 Acute cholecystitis
0.016 0.984 0.000
N05.6 Dense deposit disease
0.000 0.984 0.016
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.984 0.016
N05.0 Minor glomerular abnormality
0.000 0.984 0.016
M35 Other systemic involvement of connective tissue
0.000 0.985 0.015
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.985 0.015
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.986 0.014
E70.3 Albinism
0.000 0.986 0.014
N05.7 Diffuse crescentic glomerulonephritis
0.000 0.986 0.014
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.986 0.014
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.014 0.986 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.986 0.014
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.986 0.014
E70.2 Disorders of tyrosine metabolism
0.000 0.986 0.014
E70.1 Other hyperphenylalaninaemias
0.000 0.986 0.014
E70.0 Classical phenylketonuria
0.000 0.986 0.014
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.986 0.014
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.986 0.014
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.986 0.014
E74.2 Disorders of galactose metabolism
0.000 0.986 0.014
E74.1 Disorders of fructose metabolism
0.000 0.986 0.014
E74.0 Glycogen storage disease
0.000 0.986 0.014
E71.3 Disorders of fatty-acid metabolism
0.001 0.986 0.014
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.986 0.014
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.986 0.014
E71.0 Maple-syrup-urine disease
0.001 0.986 0.014
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.986 0.014
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.986 0.014
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.986 0.014
E76.2 Other mucopolysaccharidoses
0.001 0.986 0.014
E76.1 Mucopolysaccharidosis, type II
0.001 0.986 0.014
E76.0 Mucopolysaccharidosis, type I
0.001 0.986 0.014
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.986 0.014
E77.8 Other disorders of glycoprotein metabolism
0.001 0.986 0.014
E77.1 Defects in glycoprotein degradation
0.001 0.986 0.014
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.986 0.014
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.986 0.014
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.986 0.014
E72.5 Disorders of glycine metabolism
0.000 0.986 0.014
E72.4 Disorders of ornithine metabolism
0.000 0.986 0.014
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.986 0.014
E72.2 Disorders of urea cycle metabolism
0.000 0.986 0.014
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.986 0.014
E72.0 Disorders of amino-acid transport
0.000 0.986 0.014
E75.6 Lipid storage disorder, unspecified
0.001 0.986 0.013
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.986 0.013
E75.3 Sphingolipidosis, unspecified
0.001 0.986 0.013
E75.2 Other sphingolipidosis
0.001 0.986 0.013
E75.1 Other gangliosidosis
0.001 0.986 0.013
E75.0 GM2 gangliosidosis
0.001 0.986 0.013
E84.8 Cystic fibrosis with other manifestations
0.001 0.986 0.013
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.986 0.013
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.986 0.013
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.986 0.013
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.986 0.013
E79.1 Lesch-Nyhan syndrome
0.001 0.986 0.013
E75.5 Other lipid storage disorders
0.000 0.986 0.013
E84.9 Cystic fibrosis, unspecified
0.000 0.987 0.013
M35.2 Behcet's disease
0.000 0.987 0.013
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.987 0.012
E85 Amyloidosis
0.001 0.987 0.012
E11 Non-insulin-dependent diabetes mellitus
0.000 0.987 0.013
E73.8 Other lactose intolerance
0.000 0.987 0.012
E73.1 Secondary lactase deficiency
0.000 0.987 0.012
E73.0 Congenital lactase deficiency
0.000 0.987 0.012
E89.3 Postprocedural hypopituitarism
0.000 0.988 0.012
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.988 0.011
G90.2 Horner's syndrome
0.000 0.989 0.011
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.989 0.011
G90 Disorders of autonomic nervous system
0.000 0.989 0.011
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.989 0.011
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.989 0.011
M35.5 Multifocal fibrosclerosis
0.000 0.989 0.011
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.989 0.011
G90.0 Idiopathic peripheral autonomic neuropathy
0.000 0.989 0.011
E88 Other metabolic disorders
0.001 0.989 0.010
H26.9 Cataract, unspecified
0.000 0.989 0.011
M35.8 Other specified systemic involvement of connective tissue
0.000 0.989 0.011
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.989 0.010
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.989 0.010
E89.5 Postprocedural testicular hypofunction
0.000 0.989 0.010
E73.9 Lactose intolerance, unspecified
0.000 0.989 0.010
E66.2 Extreme obesity with alveolar hypoventilation
0.001 0.990 0.010
E89.2 Postprocedural hypoparathyroidism
0.000 0.990 0.010
E89.4 Postprocedural ovarian failure
0.000 0.990 0.010
G90.3 Multisystem degeneration
0.000 0.990 0.010
E11.6 With other specified complications
0.000 0.990 0.010
G57.6 Lesion of plantar nerve
0.010 0.990 0.000
E89.1 Postprocedural hypoinsulinaemia
0.000 0.990 0.009
G90.9 Disorder of autonomic nervous system, unspecified
0.000 0.990 0.009
M35.1 Other overlap syndromes
0.000 0.990 0.009
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.991 0.009
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.991 0.009
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.991 0.009
E11.7 With multiple complications
0.000 0.991 0.009
M35.7 Hypermobility syndrome
0.000 0.991 0.009
E85.3 Secondary systemic amyloidosis
0.001 0.991 0.009
E80.2 Other porphyria
0.000 0.991 0.009
E83.5 Disorders of calcium metabolism
0.004 0.991 0.005
E85.9 Amyloidosis, unspecified
0.000 0.991 0.008
E85.8 Other amyloidosis
0.001 0.991 0.008
G90.8 Other disorders of autonomic nervous system
0.000 0.991 0.009
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.991 0.008
E80.5 Crigler-Najjar syndrome
0.000 0.991 0.008
E80.3 Defects of catalase and peroxydase
0.000 0.991 0.008
E80.0 Hereditary erythropoietic porphyria
0.000 0.991 0.008
E11.1 With ketoacidosis
0.000 0.991 0.009
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.991 0.009
E80.6 Other disorders of bilirubin metabolism
0.000 0.991 0.008
E88.8 Other specified metabolic disorders
0.001 0.992 0.008
E88.2 Lipomatosis, not elsewhere classified
0.001 0.992 0.008
E11.0 With coma
0.000 0.992 0.008
G90.4 Autonomic dysreflexia
0.000 0.992 0.008
G90.1 Familial dysautonomia [Riley-Day]
0.000 0.992 0.008
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.992 0.008
E88.9 Metabolic disorder, unspecified
0.001 0.992 0.007
E88.3 Tumour lysis syndrome
0.001 0.992 0.007
E11.2 With renal complications
0.000 0.993 0.007
M77.47 Metatarsalgia-Ankle/Foot
0.007 0.993 0.000
E11.8 With unspecified complications
0.000 0.993 0.007
X23.9 Unspecified place
0.000 0.993 0.007
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.993 0.007
E80.1 Porphyria cutanea tarda
0.001 0.993 0.006
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.007 0.993 0.000
M67.8 Other specified disorders of synovium and tendon
0.000 0.994 0.006
N95.0 Postmenopausal bleeding
0.006 0.994 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.994 0.005
E78.6 Lipoprotein deficiency
0.000 0.994 0.006
E78.8 Other disorders of lipoprotein metabolism
0.000 0.994 0.006
E85.4 Organ-limited amyloidosis
0.001 0.994 0.005
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.995 0.005
E78.1 Pure hyperglyceridaemia
0.000 0.995 0.005
X23 Contact with hornets, wasps and bees
0.000 0.995 0.005
N00-N08 Glomerular diseases
0.000 0.995 0.005
D68.2 Hereditary deficiency of other clotting factors
0.005 0.995 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.995 0.005
X23.0 Home
0.000 0.995 0.005
E66.8 Other obesity
0.000 0.995 0.005
G57 Mononeuropathies of lower limb
0.005 0.995 0.000
E78.4 Other hyperlipidaemia
0.000 0.995 0.005
L08 Other local infections of skin and subcutaneous tissue
0.000 0.995 0.005
E78.3 Hyperchylomicronaemia
0.000 0.995 0.005
Z93.2 Ileostomy status
0.000 0.995 0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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