TreeWAS – Variant ID: rs28453840

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C34.1 Upper lobe, bronchus or lung	0.020	0.980	0.000
C34 Malignant neoplasm of bronchus and lung	0.020	0.980	0.000
C34.9 Bronchus or lung, unspecified	0.019	0.981	0.000
C34.0 Main bronchus	0.019	0.981	0.000
C34.8 Overlapping lesion of bronchus and lung	0.015	0.984	0.000
C34.2 Middle lobe, bronchus or lung	0.013	0.987	0.000
C34.3 Lower lobe, bronchus or lung	0.011	0.989	0.000
Z98.8 Other specified postsurgical states	0.011	0.989	0.000
N61 Inflammatory disorders of breast	0.010	0.990	0.000
N64.5 Other signs and symptoms in breast	0.010	0.990	0.000
I31.3 Pericardial effusion (noninflammatory)	0.010	0.990	0.000
N60-N64 Disorders of breast	0.009	0.991	0.000
N64 Other disorders of breast	0.009	0.991	0.000
N60 Benign mammary dysplasia	0.008	0.992	0.000
N62 Hypertrophy of breast	0.008	0.992	0.000
N60.0 Solitary cyst of breast	0.008	0.992	0.000
N64.4 Mastodynia	0.008	0.992	0.000
N64.1 Fat necrosis of breast	0.008	0.992	0.000
N43.3 Hydrocele, unspecified	0.008	0.992	0.000
N60.4 Mammary duct ectasia	0.007	0.992	0.000
I31 Other diseases of pericardium	0.007	0.993	0.000
N60.1 Diffuse cystic mastopathy	0.007	0.993	0.000
I31.9 Disease of pericardium, unspecified	0.007	0.993	0.000
K11.5 Sialolithiasis	0.007	0.993	0.000
N64.3 Galactorrhoea not associated with childbirth	0.007	0.993	0.000
N64.0 Fissure and fistula of nipple	0.007	0.993	0.000
N60.3 Fibrosclerosis of breast	0.007	0.993	0.000
N64.2 Atrophy of breast	0.007	0.993	0.000
N64.8 Other specified disorders of breast	0.007	0.993	0.000
H35.3 Degeneration of macula and posterior pole	0.000	0.994	0.006
I31.0 Chronic adhesive pericarditis	0.006	0.994	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.994	0.006
N60.9 Benign mammary dysplasia, unspecified	0.006	0.994	0.000
N63 Unspecified lump in breast	0.006	0.994	0.000
I31.8 Other specified diseases of pericardium	0.005	0.994	0.000
I31.2 Haemopericardium, not elsewhere classified	0.005	0.994	0.000
I31.1 Chronic constrictive pericarditis	0.006	0.994	0.000
O71.7 Obstetric haematoma of pelvis	0.000	0.995	0.005
O71 Other obstetric trauma	0.000	0.996	0.004
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.996	0.004
N94.6 Dysmenorrhoea, unspecified	0.000	0.996	0.004
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.004	0.996	0.000
O71.8 Other specified obstetric trauma	0.000	0.996	0.004
K11 Diseases of salivary glands	0.004	0.996	0.000
K11.1 Hypertrophy of salivary gland	0.004	0.996	0.000
K11.9 Disease of salivary gland, unspecified	0.004	0.996	0.000
O71.3 Obstetric laceration of cervix	0.000	0.996	0.004
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.004	0.996	0.000
N70.1 Chronic salpingitis and oophoritis	0.000	0.996	0.004
K11.8 Other diseases of salivary glands	0.004	0.996	0.000
O71.9 Obstetric trauma, unspecified	0.000	0.996	0.004
N43 Hydrocele and spermatocele	0.004	0.996	0.000
I67.9 Cerebrovascular disease, unspecified	0.000	0.996	0.004
O71.6 Obstetric damage to pelvic joints and ligaments	0.000	0.996	0.004
G45.3 Amaurosis fugax	0.004	0.996	0.000
N81.2 Incomplete uterovaginal prolapse	0.004	0.996	0.000
D59 Acquired haemolytic anaemia	0.000	0.996	0.004
O71.5 Other obstetric injury to pelvic organs	0.000	0.996	0.003
N60.2 Fibroadenosis of breast	0.003	0.996	0.000
O71.2 Postpartum inversion of uterus	0.000	0.997	0.003
O71.1 Rupture of uterus during labour	0.000	0.997	0.003
O71.0 Rupture of uterus before onset of labour	0.000	0.997	0.003
G45.4 Transient global amnesia	0.003	0.997	0.000
N60.8 Other benign mammary dysplasias	0.003	0.997	0.000
K11.4 Fistula of salivary gland	0.003	0.997	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.003	0.997	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.997	0.003
K11.0 Atrophy of salivary gland	0.003	0.997	0.000
O71.4 Obstetric high vaginal laceration alone	0.000	0.997	0.003
N43.0 Encysted hydrocele	0.003	0.997	0.000
K11.3 Abscess of salivary gland	0.003	0.997	0.000
C32 Malignant neoplasm of larynx	0.003	0.997	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.003	0.997	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.000	0.997	0.003
N64.9 Disorder of breast, unspecified	0.003	0.997	0.001
D59.1 Other autoimmune haemolytic anaemias	0.000	0.997	0.003
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.003	0.997	0.000
N43.2 Other hydrocele	0.003	0.997	0.000
K11.7 Disturbances of salivary secretion	0.003	0.997	0.000
H54.9 Unspecified visual impairment (binocular)	0.003	0.997	0.000
N43.1 Infected hydrocele	0.003	0.997	0.000
C31 Malignant neoplasm of accessory sinuses	0.003	0.997	0.000
M51.8 Other specified intervertebral disk disorders	0.000	0.997	0.003
C38 Malignant neoplasm of heart, mediastinum and pleura	0.003	0.997	0.000
D59.8 Other acquired haemolytic anaemias	0.000	0.997	0.003
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.997	0.003
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.997	0.003
D59.3 Haemolytic-uraemic syndrome	0.000	0.997	0.003
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.997	0.003
G45.1 Carotid artery syndrome (hemispheric)	0.003	0.997	0.000
C33 Malignant neoplasm of trachea	0.003	0.997	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.003	0.997	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.997	0.003
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.997	0.003
D58 Other hereditary haemolytic anaemias	0.000	0.997	0.003
N97.9 Female infertility, unspecified	0.003	0.997	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.997	0.003
N43.4 Spermatocele	0.003	0.997	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.997	0.003
C37 Malignant neoplasm of thymus	0.002	0.997	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.003	0.997	0.000
G45.0 Vertebro-basilar artery syndrome	0.003	0.997	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.003	0.997	0.000
O42 Premature rupture of membranes	0.000	0.997	0.003
C32.3 Laryngeal cartilage	0.002	0.997	0.000
C32.2 Subglottis	0.002	0.997	0.000
I82.8 Embolism and thrombosis of other specified veins	0.003	0.997	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.997	0.003
C32.8 Overlapping lesion of larynx	0.002	0.997	0.000
D55-D59 Haemolytic anaemias	0.000	0.997	0.003
C32.1 Supraglottis	0.002	0.997	0.000
C39.9 Ill-defined sites within the respiratory system	0.002	0.997	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.002	0.997	0.000
C39.0 Upper respiratory tract, part unspecified	0.002	0.997	0.000
K11.2 Sialoadenitis	0.002	0.997	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
K75.9 Inflammatory liver disease, unspecified	0.002	0.998	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
S29.9 Unspecified injury of thorax	0.000	0.998	0.002
K11.6 Mucocele of salivary gland	0.002	0.998	0.000
Z02.8 Other examinations for administrative purposes	0.002	0.998	0.000
C32.0 Glottis	0.002	0.998	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.000	0.998	0.002
C32.9 Larynx, unspecified	0.002	0.998	0.000
Z90.2 Acquired absence of lung [part of]	0.002	0.998	0.000
C31.9 Accessory sinus, unspecified	0.002	0.998	0.000
C31.8 Overlapping lesion of accessory sinuses	0.002	0.998	0.000
C31.3 Sphenoidal sinus	0.002	0.998	0.000
C31.2 Frontal sinus	0.002	0.998	0.000
C31.1 Ethmoidal sinus	0.002	0.998	0.000
I82.2 Embolism and thrombosis of vena cava	0.002	0.998	0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.002	0.998	0.000
C38.2 Posterior mediastinum	0.002	0.998	0.000
C38.1 Anterior mediastinum	0.002	0.998	0.000
C38.0 Heart	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
D58.2 Other haemoglobinopathies	0.000	0.998	0.002
I82 Other venous embolism and thrombosis	0.002	0.998	0.000
C38.4 Pleura	0.002	0.998	0.000
C30.1 Middle ear	0.002	0.998	0.000
C92.0 Acute myeloid leukaemia	0.000	0.998	0.002
C38.3 Mediastinum, part unspecified	0.002	0.998	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.000	0.998	0.002
D58.1 Hereditary elliptocytosis	0.000	0.998	0.002
E16.2 Hypoglycaemia, unspecified	0.000	0.998	0.002
C31.0 Maxillary sinus	0.002	0.998	0.000
N70 Salpingitis and oophoritis	0.000	0.998	0.002
G30.9 Alzheimer's disease, unspecified	0.002	0.998	0.000
X78.0 Home	0.000	0.998	0.002
D56 Thalassaemia	0.000	0.998	0.002
D89.3 Immune reconstitution syndrome	0.000	0.998	0.002
E16.1 Other hypoglycaemia	0.000	0.998	0.002
N70.9 Salpingitis and oophoritis, unspecified	0.000	0.998	0.002
K22.7 Barrett's oesophagus	0.002	0.998	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.002	0.998	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.998	0.002
D55 Anaemia due to enzyme disorders	0.000	0.998	0.002
M71.38 Other bursal cyst (Other)	0.000	0.998	0.002
D58.0 Hereditary spherocytosis	0.000	0.998	0.002
M75.9 Shoulder lesion, unspecified	0.000	0.998	0.002
D89.1 Cryoglobulinaemia	0.000	0.998	0.002
I82.0 Budd-Chiari syndrome	0.002	0.998	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.998	0.002
M54.50 Low back pain (Multiple sites in spine)	0.002	0.998	0.000
D57 Sickle-cell disorders	0.000	0.998	0.002
D56.3 Thalassaemia trait	0.000	0.998	0.002
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.998	0.002
C30.0 Nasal cavity	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.002	0.998	0.000
I82.1 Thrombophlebitis migrans	0.002	0.998	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.002	0.998	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.002	0.998	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.002	0.998	0.000
I85.0 Oesophageal varices with bleeding	0.002	0.998	0.000
Z99.8 Dependence on other enabling machines and devices	0.002	0.998	0.000
I82.3 Embolism and thrombosis of renal vein	0.002	0.998	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.002	0.998	0.000
N70.0 Acute salpingitis and oophoritis	0.000	0.998	0.002
D56.8 Other thalassaemias	0.000	0.998	0.002
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.000	0.998	0.002
D56.2 Delta-beta thalassaemia	0.000	0.998	0.002
D56.0 Alpha thalassaemia	0.000	0.998	0.002
D63.0 Anaemia in neoplastic disease	0.002	0.998	0.000
M35.0 Sicca syndrome [Sjogren]	0.002	0.998	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.998	0.002
D55.8 Other anaemias due to enzyme disorders	0.000	0.998	0.002
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.998	0.002
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.998	0.002
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.998	0.002
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.998	0.002
D56.9 Thalassaemia, unspecified	0.000	0.998	0.002
G40.7 Petit mal, unspecified, without grand mal seizures	0.002	0.998	0.000
U80.1 Methicillin resistant agent	0.002	0.998	0.000
D56.1 Beta thalassaemia	0.000	0.998	0.002
G45.9 Transient cerebral ischaemic attack, unspecified	0.002	0.998	0.000
D57.8 Other sickle-cell disorders	0.000	0.998	0.001
D57.2 Double heterozygous sickling disorders	0.000	0.998	0.001
D57.0 Sickle-cell anaemia with crisis	0.000	0.998	0.001
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.998	0.002
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.998	0.002
E16.4 Abnormal secretion of gastrin	0.000	0.998	0.002
E16.3 Increased secretion of glucagon	0.000	0.998	0.002
R10.1 Pain localised to upper abdomen	0.002	0.998	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.002	0.998	0.000
D57.1 Sickle-cell anaemia without crisis	0.000	0.998	0.001
Z45.8 Adjustment and management of other implanted devices	0.000	0.998	0.002
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.998	0.002
E73.9 Lactose intolerance, unspecified	0.000	0.998	0.002
H72.8 Other perforations of tympanic membrane	0.002	0.998	0.000
D57.3 Sickle-cell trait	0.000	0.998	0.001
S40.0 Contusion of shoulder and upper arm	0.002	0.998	0.000
G40.5 Special epileptic syndromes	0.002	0.998	0.000
H20.1 Chronic iridocyclitis	0.000	0.998	0.002
G44.3 Chronic posttraumatic headache	0.001	0.998	0.000
G44.1 Vascular headache, not elsewhere classified	0.001	0.998	0.000
G44.0 Cluster headache syndrome	0.002	0.998	0.000
G44 Other headache syndromes	0.002	0.998	0.000
G40-G47 Episodic and paroxysmal disorders	0.002	0.998	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
K31.7 Polyp of stomach and duodenum	0.002	0.998	0.000
Z90.5 Acquired absence of kidney	0.002	0.998	0.000
G40.8 Other epilepsy	0.001	0.998	0.000
S72.40 Fracture of lower end of femur (closed)	0.001	0.998	0.000
G40 Epilepsy	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.000	0.999	0.001
K31.9 Disease of stomach and duodenum, unspecified	0.001	0.999	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.001	0.999	0.000
K62.4 Stenosis of anus and rectum	0.001	0.999	0.000
N99.0 Postprocedural renal failure	0.001	0.999	0.000
O14.1 Severe preeclampsia	0.001	0.999	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.001	0.999	0.000
D36.7 Other specified sites	0.001	0.999	0.000
H20.0 Acute and subacute iridocyclitis	0.000	0.999	0.001
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.999	0.001
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.001	0.999	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.001	0.999	0.000
I47.2 Ventricular tachycardia	0.001	0.999	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.001	0.999	0.000
H72 Perforation of tympanic membrane	0.001	0.999	0.000
A63.0 Anogenital (venereal) warts	0.001	0.999	0.000
G46.7 Other lacunar syndromes	0.001	0.999	0.000
G46.3 Brain stem stroke syndrome	0.001	0.999	0.000
H20 Iridocyclitis	0.000	0.999	0.001
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.001	0.999	0.000
M75.4 Impingement syndrome of shoulder	0.000	0.999	0.001
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
S82.20 Fracture of shaft of tibia (closed)	0.001	0.999	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.999	0.001
N99.2 Postprocedural adhesions of vagina	0.001	0.999	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
R45.1 Restlessness and agitation	0.001	0.999	0.000
S22.40 Multiple fractures of ribs (closed)	0.001	0.999	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.001	0.999	0.000
G44.8 Other specified headache syndromes	0.001	0.999	0.000
N99.5 Malfunction of external stoma of urinary tract	0.001	0.999	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.001	0.999	0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.001	0.999	0.000
G46.6 Pure sensory lacunar syndrome	0.001	0.999	0.000
G46.5 Pure motor lacunar syndrome	0.001	0.999	0.000
G46.4 Cerebellar stroke syndrome	0.001	0.999	0.000
G46.1 Anterior cerebral artery syndrome	0.001	0.999	0.000
G46.0 Middle cerebral artery syndrome	0.001	0.999	0.000
O14.0 Moderate preeclampsia	0.001	0.999	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.001	0.999	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.001	0.999	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.001	0.999	0.000
G40.9 Epilepsy, unspecified	0.001	0.999	0.000
H20.9 Iridocyclitis, unspecified	0.000	0.999	0.001
U80 Agent resistant to penicillin and related antibiotics	0.001	0.999	0.000
D48.7 Other specified sites	0.000	0.999	0.001
G46.2 Posterior cerebral artery syndrome	0.001	0.999	0.000
H35.9 Retinal disorder, unspecified	0.000	0.999	0.001
K85.9 Acute pancreatitis, unspecified	0.001	0.999	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.000	0.999	0.001
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.001	0.999	0.000
G41 Status epilepticus	0.001	0.999	0.000
H35 Other retinal disorders	0.000	0.999	0.001
G25.8 Other specified extrapyramidal and movement disorders	0.001	0.999	0.000
G41.2 Complex partial status epilepticus	0.001	0.999	0.000
H20.2 Lens-induced iridocyclitis	0.000	0.999	0.001
H72.2 Other marginal perforations of tympanic membrane	0.001	0.999	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.001	0.999	0.000
E06.3 Autoimmune thyroiditis	0.001	0.999	0.000
H35.0 Background retinopathy and retinal vascular changes	0.000	0.999	0.001
H72.1 Attic perforation of tympanic membrane	0.001	0.999	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.001	0.999	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.999	0.001
D63.1 Anaemia in other chronic diseases classified elsewhere	0.001	0.999	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.001	0.999	0.000
N21.0 Calculus in bladder	0.001	0.999	0.000
R84.5 Abnormal microbiological findings	0.000	0.999	0.001
O15 Eclampsia	0.001	0.999	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.999	0.001
D23.6 Skin of upper limb, including shoulder	0.001	0.999	0.000
G25.0 Essential tremor	0.001	0.999	0.000
G30.8 Other Alzheimer's disease	0.001	0.999	0.000
H54.5 Low vision, one eye	0.001	0.999	0.000
O14.2 HELLP syndrome	0.001	0.999	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
Q27.3 Peripheral arteriovenous malformation	0.001	0.999	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
D39.1 Ovary	0.001	0.999	0.000
G41.0 Grand mal status epilepticus	0.001	0.999	0.000
H35.1 Retinopathy of prematurity	0.000	0.999	0.001
Z99.3 Dependence on wheelchair	0.001	0.999	0.000
G30.1 Alzheimer's disease with late onset	0.001	0.999	0.000
G41.1 Petit mal status epilepticus	0.001	0.999	0.000
O86.0 Infection of obstetric surgical wound	0.001	0.999	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
U80.0 Penicillin resistant agent	0.001	0.999	0.000
G30 Alzheimer's disease	0.001	0.999	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.001	0.999	0.000
H35.8 Other specified retinal disorders	0.000	0.999	0.001
S05.8 Other injuries of eye and orbit	0.000	0.999	0.001
U81.0 Vancomycin resistant agent	0.001	0.999	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.001	0.999	0.000
H54 Blindness and low vision	0.001	0.999	0.000
M54.56 Low back pain (Lumbar region)	0.001	0.999	0.000
H35.5 Hereditary retinal dystrophy	0.000	0.999	0.001
O15.9 Eclampsia, unspecified as to time period	0.001	0.999	0.000
O15.2 Eclampsia in the puerperium	0.001	0.999	0.000
O15.1 Eclampsia in labour	0.001	0.999	0.000
O15.0 Eclampsia in pregnancy	0.001	0.999	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.999	0.001
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.001	0.999	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.001	0.999	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.001	0.999	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.999	0.001
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.000	0.999	0.001
O32.9 Maternal care for malpresentation of foetus, unspecified	0.001	0.999	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.001	0.999	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
U80.8 Agent resistant to other penicillin-related antibiotic	0.001	0.999	0.000
R02 Gangrene, not elsewhere classified	0.001	0.999	0.000
X78 Intentional self-harm by sharp object	0.000	0.999	0.001
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.001	0.999	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.000	0.999	0.001
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.999	0.001
H54.4 Blindness, one eye	0.001	0.999	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.001	0.999	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.001	0.999	0.000
U81.8 Agent resistant to other vancomycin-related antibiotic	0.001	0.999	0.000
X78.2 School, other institution and public administrative area	0.000	0.999	0.001
Z04.8 Examination and observation for other specified reasons	0.001	0.999	0.000
Z89.5 Acquired absence of leg at or below knee	0.000	0.999	0.001
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.001	0.999	0.000
G41.8 Other status epilepticus	0.001	0.999	0.000
G43.1 Migraine with aura [classical migraine]	0.001	0.999	0.000
H54.6 Unqualified visual loss, one eye	0.001	0.999	0.000
M71.3 Other bursal cyst	0.000	0.999	0.001
S40.8 Other superficial injuries of shoulder and upper arm	0.001	0.999	0.000
Z45.1 Adjustment and management of infusion pump	0.000	0.999	0.001
S29 Other and unspecified injuries of thorax	0.000	0.999	0.001
S40 Superficial injury of shoulder and upper arm	0.001	0.999	0.000
M71.37 Other bursal cyst (Ankle and foot)	0.000	0.999	0.001
C21.0 Anus, unspecified	0.001	0.999	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.000	0.999	0.001
R26.3 Immobility	0.001	0.999	0.000
R41.2 Retrograde amnesia	0.000	0.999	0.001
S01.0 Open wound of scalp	0.000	0.999	0.001
X78.9 Unspecified place	0.000	0.999	0.001
X78.8 Other specified place	0.000	0.999	0.001
X78.7 Farm	0.000	0.999	0.001
X78.6 Industrial and construction area	0.000	0.999	0.001
X78.5 Trade and service area	0.000	0.999	0.001
X78.4 Street and highway	0.000	0.999	0.001
X78.3 Sports and athletics area	0.000	0.999	0.001
X78.1 Residential institution	0.000	0.999	0.001
U81 Agent resistant to vancomycin and related antibiotics	0.001	0.999	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.001	0.999	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
F44.4 Dissociative motor disorders	0.000	0.999	0.001
G41.9 Status epilepticus, unspecified	0.001	0.999	0.000
G43.0 Migraine without aura [common migraine]	0.001	0.999	0.000
H54.3 Unqualified visual loss, both eyes	0.001	0.999	0.000
H54.2 Low vision, both eyes	0.001	0.999	0.000
K85.1 Biliary acute pancreatitis	0.001	0.999	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
S29.7 Multiple injuries of thorax	0.000	0.999	0.001
S40.7 Multiple superficial injuries of shoulder and upper arm	0.001	0.999	0.000
N97 Female infertility	0.001	0.999	0.000
Z02 Examination and encounter for administrative purposes	0.001	0.999	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.001	0.999	0.000
M71.39 Other bursal cyst (Site unspecified)	0.000	0.999	0.001
M71.36 Other bursal cyst (Lower leg)	0.000	0.999	0.001
M71.35 Other bursal cyst (Pelvic region and thigh)	0.000	0.999	0.001
M71.33 Other bursal cyst (Forearm)	0.000	0.999	0.001
M71.32 Other bursal cyst (Upper arm)	0.000	0.999	0.001
M71.31 Other bursal cyst (Shoulder region)	0.000	0.999	0.001
M71.30 Other bursal cyst (Multiple sites)	0.000	0.999	0.001
X78.99 Intentional self-harm by sharp object: Unspecified place: During unspecified activity	0.000	0.999	0.001
M85.8 Other specified disorders of bone density and structure	0.000	0.999	0.001
N97.4 Female infertility associated with male factors	0.001	0.999	0.000
N97.0 Female infertility associated with anovulation	0.001	0.999	0.000
S82.8 Fractures of other parts of lower leg	0.001	0.999	0.000
Z99.1 Dependence on respirator	0.001	0.999	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
M54.55 Low back pain (Thoracolumbar region)	0.001	0.999	0.000
M54.54 Low back pain-Thoracic	0.001	0.999	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.001	0.999	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.999	0.001
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.999	0.001
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.999	0.001
S82.86 Maisonneuve's fracture	0.001	0.999	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.001	0.999	0.000
N97.3 Female infertility of cervical origin	0.001	0.999	0.000
N97.2 Female infertility of uterine origin	0.001	0.999	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
S29.8 Other specified injuries of thorax	0.000	0.999	0.001
S29.0 Injury of muscle and tendon at thorax level	0.000	0.999	0.001
Z02.9 Examination for administrative purposes, unspecified	0.001	0.999	0.000
Z02.7 Issue of medical certificate	0.001	0.999	0.000
Z02.6 Examination for insurance purposes	0.001	0.999	0.000
Z02.5 Examination for participation in sport	0.001	0.999	0.000
Z02.4 Examination for driving licence	0.001	0.999	0.000
Z02.3 Examination for recruitment to armed forces	0.001	0.999	0.000
Z02.2 Examination for admission to residential institution	0.001	0.999	0.000
Z02.1 Pre-employment examination	0.001	0.999	0.000
Z02.0 Examination for admission to educational institution	0.001	0.999	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.001	0.999	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.001	0.999	0.000
M47.82 Other spondylosis (Cervical region)	0.001	0.999	0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.000	0.999	0.001
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.001	0.999	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.999	0.001
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.999	0.001
F44.9 Dissociative [conversion] disorder, unspecified	0.000	0.999	0.001
G97.1 Other reaction to spinal and lumbar puncture	0.001	0.999	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
M54.52 Low back pain-Cervical	0.001	0.999	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.001	0.999	0.000
C60.0 Prepuce	0.000	0.999	0.001
G43.2 Status migrainosus	0.001	0.999	0.000
H35.7 Separation of retinal layers	0.000	0.999	0.001
H74.4 Polyp of middle ear	0.001	0.999	0.000
M54.5 Low back pain	0.001	0.999	0.000
N97.8 Female infertility of other origin	0.001	0.999	0.000
O12.2 Gestational oedema with proteinuria	0.001	0.999	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.001	0.999	0.000
R84.6 Abnormal cytological findings	0.000	0.999	0.001
M54.53 Low back pain-Cervicothoracic	0.001	0.999	0.000
M54.51 Low back pain-Occipit-atl-axl	0.001	0.999	0.000
D82.1 Di George's syndrome	0.000	0.999	0.001
J11.1 Influenza with other respiratory manifestations, virus not identified	0.000	0.999	0.001
M25.6 Stiffness of joint, not elsewhere classified	0.001	0.999	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.001	0.999	0.000
Z99.4 Dependence on artificial heart	0.001	0.999	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.001	0.999	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.001	0.999	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M71.34 Other bursal cyst (Hand)	0.000	0.999	0.001
M79.10 Myalgia (Multiple sites)	0.000	0.999	0.001
S82.81 Fractures of other parts of lower leg (open)	0.001	0.999	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.999	0.001
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.999	0.001
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.999	0.001
D82.2 Immunodeficiency with short-limbed stature	0.000	0.999	0.001
D82.0 Wiskott-Aldrich syndrome	0.000	0.999	0.001
H54.7 Unspecified visual loss	0.001	0.999	0.000
H54.1 Blindness, one eye, low vision, other eye	0.001	0.999	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.001	0.999	0.000
W25.9 Unspecified place	0.000	0.999	0.001
D82 Immunodeficiency associated with other major defects	0.000	0.999	0.001
G43 Migraine	0.001	0.999	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.999	0.001
B02.9 Zoster without complication	0.001	0.999	0.000
G24.9 Dystonia, unspecified	0.000	0.999	0.001
G30.0 Alzheimer's disease with early onset	0.001	0.999	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.001	0.999	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.001	0.999	0.000
N76.4 Abscess of vulva	0.000	0.999	0.001
N99.1 Postprocedural urethral stricture	0.001	0.999	0.000
Z83.3 Family history of diabetes mellitus	0.000	0.999	0.001
Z99.9 Dependence on unspecified enabling machine and device	0.001	0.999	0.000
B91 Sequelae of poliomyelitis	0.000	0.999	0.001
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.999	0.001
S72.41 Fracture of lower end of femur (open)	0.001	0.999	0.000
A48.1 Legionnaires' disease	0.000	0.999	0.001
D84.8 Other specified immunodeficiencies	0.000	0.999	0.001
H35.2 Other proliferative retinopathy	0.000	0.999	0.001
M17.1 Other primary gonarthrosis	0.000	0.999	0.001
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.001	0.999	0.000
U06.9 Emergency use of U06.9	0.001	0.999	0.000
U06.8 Emergency use of U06.8	0.001	0.999	0.000
U06.7 Emergency use of U06.7	0.001	0.999	0.000
U06.6 Emergency use of U06.6	0.001	0.999	0.000
U06.5 Emergency use of U06.5	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations