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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28502093
log Bayes Factor = 12.5607
Chromosome 15   position 78,024,644  (GRCh37) Explore rs28502093 on Ensembl!
Variant rs28502093 is part of Cluster X0064

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I50 Heart failure
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E11.9 Without complications
1.000 0.000 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
# Top node
0.996 0.004 0.000
E11.3 With ophthalmic complications
0.995 0.005 0.000
I24 Other acute ischaemic heart diseases
0.993 0.007 0.000
I50.1 Left ventricular failure
0.990 0.010 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.989 0.011 0.000
I25.1 Atherosclerotic heart disease
0.989 0.011 0.000
I50.9 Heart failure, unspecified
0.987 0.013 0.000
K80 Cholelithiasis
0.987 0.013 0.000
I50.0 Congestive heart failure
0.987 0.013 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.984 0.016 0.000
E78.5 Hyperlipidaemia, unspecified
0.981 0.019 0.000
K83 Other diseases of biliary tract
0.970 0.030 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.968 0.032 0.000
E78.0 Pure hypercholesterolaemia
0.964 0.036 0.000
K83.0 Cholangitis
0.963 0.037 0.000
K86 Other diseases of pancreas
0.960 0.040 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.958 0.042 0.000
Chapter VII Diseases of the eye and adnexa
0.954 0.046 0.000
I30 Acute pericarditis
0.952 0.048 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.949 0.051 0.000
I42 Cardiomyopathy
0.948 0.052 0.000
H30-H36 Disorders of choroid and retina
0.946 0.054 0.000
K85 Acute pancreatitis
0.945 0.055 0.000
I10-I15 Hypertensive diseases
0.940 0.060 0.000
H53-H54 Visual disturbances and blindness
0.937 0.063 0.000
I22 Subsequent myocardial infarction
0.936 0.064 0.000
I49 Other cardiac arrhythmias
0.932 0.068 0.000
H53 Visual disturbances
0.928 0.072 0.000
H36 Retinal disorders in diseases classified elsewhere
0.926 0.074 0.000
Chapter X Diseases of the respiratory system
0.920 0.080 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.919 0.081 0.000
H36.0 Diabetic retinopathy
0.912 0.088 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.911 0.089 0.000
Z95.1 Presence of aortocoronary bypass graft
0.910 0.090 0.000
I30.9 Acute pericarditis, unspecified
0.906 0.094 0.000
I24.8 Other forms of acute ischaemic heart disease
0.903 0.097 0.000
H53.0 Amblyopia ex anopsia
0.902 0.098 0.000
Z95.0 Presence of cardiac pacemaker
0.901 0.099 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.900 0.100 0.000
I51 Complications and ill-defined descriptions of heart disease
0.897 0.103 0.000
Z95.2 Presence of prosthetic heart valve
0.896 0.104 0.000
I49.0 Ventricular fibrillation and flutter
0.895 0.105 0.000
H53.8 Other visual disturbances
0.893 0.107 0.000
M05-M14 Inflammatory polyarthropathies
0.893 0.107 0.000
E78.8 Other disorders of lipoprotein metabolism
0.893 0.107 0.000
I05-I09 Chronic rheumatic heart diseases
0.890 0.110 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.888 0.112 0.000
Chapter XIV Diseases of the genitourinary system
0.884 0.116 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.883 0.117 0.000
K86.2 Cyst of pancreas
0.882 0.118 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.879 0.121 0.000
N00-N08 Glomerular diseases
0.877 0.123 0.000
E73 Lactose intolerance
0.871 0.129 0.000
I15 Secondary hypertension
0.871 0.129 0.000
K86.8 Other specified diseases of pancreas
0.870 0.130 0.000
K85.1 Biliary acute pancreatitis
0.870 0.130 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.867 0.133 0.000
J00-J06 Acute upper respiratory infections
0.866 0.134 0.000
N25-N29 Other disorders of kidney and ureter
0.865 0.135 0.000
I36 Nonrheumatic tricuspid valve disorders
0.862 0.138 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.860 0.140 0.000
I51.9 Heart disease, unspecified
0.856 0.144 0.000
E11.6 With other specified complications
0.855 0.145 0.000
I12 Hypertensive renal disease
0.854 0.146 0.000
J40-J47 Chronic lower respiratory diseases
0.853 0.147 0.000
E10 Insulin-dependent diabetes mellitus
0.843 0.157 0.000
E11.2 With renal complications
0.843 0.157 0.000
H34 Retinal vascular occlusions
0.843 0.157 0.000
I42.9 Cardiomyopathy, unspecified
0.841 0.159 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.838 0.162 0.000
Chapter I Certain infectious and parasitic diseases
0.836 0.164 0.000
Z95.4 Presence of other heart-valve replacement
0.836 0.164 0.000
J09-J18 Influenza and pneumonia
0.835 0.165 0.000
N17-N19 Renal failure
0.830 0.170 0.000
E65-E68 Obesity and other hyperalimentation
0.829 0.171 0.000
E74 Other disorders of carbohydrate metabolism
0.829 0.171 0.000
K82 Other diseases of gallbladder
0.826 0.174 0.000
I08 Multiple valve diseases
0.825 0.175 0.000
H35 Other retinal disorders
0.825 0.175 0.000
I49.5 Sick sinus syndrome
0.824 0.176 0.000
I37 Pulmonary valve disorders
0.819 0.181 0.000
N26 Unspecified contracted kidney
0.818 0.182 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.818 0.182 0.000
N02 Recurrent and persistent haematuria
0.818 0.182 0.000
J47 Bronchiectasis
0.817 0.183 0.000
M86-M90 Other osteopathies
0.815 0.185 0.000
H53.2 Diplopia
0.813 0.187 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.812 0.188 0.000
J00 Acute nasopharyngitis [common cold]
0.811 0.189 0.000
H35.8 Other specified retinal disorders
0.810 0.190 0.000
I27 Other pulmonary heart diseases
0.807 0.193 0.000
K86.9 Disease of pancreas, unspecified
0.806 0.194 0.000
M60-M63 Disorders of muscles
0.805 0.195 0.000
J42 Unspecified chronic bronchitis
0.803 0.197 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.800 0.200 0.000
M06 Other rheumatoid arthritis
0.799 0.201 0.000
H31 Other disorders of choroid
0.788 0.212 0.000
E11.8 With unspecified complications
0.788 0.212 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.784 0.216 0.000
M70-M79 Other soft tissue disorders
0.782 0.218 0.000
I49.8 Other specified cardiac arrhythmias
0.780 0.220 0.000
E73.9 Lactose intolerance, unspecified
0.780 0.220 0.000
N19 Unspecified renal failure
0.779 0.221 0.000
E20-E35 Disorders of other endocrine glands
0.777 0.223 0.000
M65-M68 Disorders of synovium and tendon
0.775 0.225 0.000
Chapter II Neoplasms
0.773 0.227 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.773 0.227 0.000
K85.8 Other acute pancreatitis
0.772 0.228 0.000
K85.9 Acute pancreatitis, unspecified
0.771 0.229 0.000
I12.0 Hypertensive renal disease with renal failure
0.769 0.231 0.000
A30-A49 Other bacterial diseases
0.765 0.235 0.000
I42.6 Alcoholic cardiomyopathy
0.764 0.236 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.762 0.238 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.762 0.238 0.000
M77 Other enthesopathies
0.760 0.240 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.759 0.241 0.000
N05 Unspecified nephritic syndrome
0.758 0.242 0.000
M14 Arthropathies in other diseases classified elsewhere
0.757 0.242 0.000
H34.8 Other retinal vascular occlusions
0.756 0.244 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.755 0.245 0.000
I30.1 Infective pericarditis
0.754 0.246 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.754 0.246 0.000
E78.4 Other hyperlipidaemia
0.754 0.246 0.000
K80.8 Other cholelithiasis
0.754 0.246 0.000
M91-M94 Chondropathies
0.753 0.247 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.752 0.248 0.000
Chapter XX External causes of morbidity and mortality
0.749 0.251 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.744 0.255 0.000
I25.3 Aneurysm of heart
0.744 0.256 0.000
E66 Obesity
0.743 0.257 0.000
B95-B98 Bacterial, viral and other infectious agents
0.741 0.259 0.000
E88 Other metabolic disorders
0.740 0.260 0.000
M05 Seropositive rheumatoid arthritis
0.740 0.260 0.000
I42.8 Other cardiomyopathies
0.740 0.260 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.740 0.260 0.000
I15.9 Seconday hypertension, unspecified
0.739 0.261 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.739 0.261 0.000
K82.1 Hydrops of gallbladder
0.738 0.262 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.738 0.262 0.000
M00-M03 Infectious arthropathies
0.738 0.262 0.000
N02.9 Unspecified
0.737 0.263 0.000
J17 Pneumonia in diseases classified elsewhere
0.736 0.264 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.736 0.264 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.736 0.264 0.000
I27.0 Primary pulmonary hypertension
0.736 0.264 0.000
I15.1 Hypertension secondary to other renal disorders
0.734 0.266 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.733 0.267 0.000
J11 Influenza, virus not identified
0.733 0.267 0.000
I22.8 Subsequent myocardial infarction of other sites
0.732 0.268 0.000
J40 Bronchitis, not specified as acute or chronic
0.730 0.270 0.000
E85 Amyloidosis
0.729 0.271 0.000
E78.1 Pure hyperglyceridaemia
0.727 0.273 0.000
E10.2 With renal complications
0.727 0.273 0.000
N04 Nephrotic syndrome
0.726 0.274 0.000
J14 Pneumonia due to Haemophilus influenzae
0.724 0.276 0.000
D46 Myelodysplastic syndromes
0.721 0.279 0.000
M90 Osteopathies in diseases classified elsewhere
0.720 0.280 0.000
E11.7 With multiple complications
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
E78.6 Lipoprotein deficiency
0.716 0.284 0.000
E78.3 Hyperchylomicronaemia
0.716 0.284 0.000
Chapter XI Diseases of the digestive system
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.715 0.285 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.714 0.285 0.000
Z95.3 Presence of xenogenic heart valve
0.714 0.286 0.000
M11 Other crystal arthropathies
0.714 0.286 0.000
M77.0 Medial epicondylitis
0.714 0.286 0.000
E11.4 With neurological complications
0.713 0.287 0.000
I24.1 Dressler's syndrome
0.712 0.288 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.711 0.289 0.000
C91 Lymphoid leukaemia
0.710 0.290 0.000
E11.1 With ketoacidosis
0.710 0.290 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.709 0.291 0.000
K80.3 Calculus of bile duct with cholangitis
0.708 0.292 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.707 0.293 0.000
I15.0 Renovascular hypertension
0.705 0.295 0.000
N25 Disorders resulting from impaired renal tubular function
0.703 0.296 0.000
I27.8 Other specified pulmonary heart diseases
0.703 0.297 0.000
I42.2 Other hypertrophic cardiomyopathy
0.702 0.298 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.701 0.299 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.700 0.300 0.000
E50-E64 Other nutritional deficiencies
0.700 0.300 0.000
I23 Certain current complications following acute myocardial infarction
0.699 0.301 0.000
M10 Gout
0.699 0.301 0.000
J10 Influenza due to identified influenza virus
0.699 0.301 0.000
J90-J94 Other diseases of pleura
0.698 0.302 0.000
N02.8 Other
0.697 0.303 0.000
M06.9 Rheumatoid arthritis, unspecified
0.697 0.303 0.000
K83.5 Biliary cyst
0.696 0.304 0.000
K83.4 Spasm of sphincter of Oddi
0.696 0.304 0.000
K83.3 Fistula of bile duct
0.696 0.304 0.000
K83.2 Perforation of bile duct
0.696 0.304 0.000
E10.9 Without complications
0.693 0.307 0.000
N18 Chronic renal failure
0.690 0.310 0.000
I37.1 Pulmonary valve insufficiency
0.689 0.311 0.000
M62 Other disorders of muscle
0.687 0.313 0.000
E11.0 With coma
0.685 0.315 0.000
C91.1 Chronic lymphocytic leukaemia
0.685 0.315 0.000
K86.1 Other chronic pancreatitis
0.684 0.316 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.683 0.317 0.000
N28.1 Cyst of kidney, acquired
0.683 0.317 0.000
I30.8 Other forms of acute pericarditis
0.683 0.317 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.683 0.317 0.000
I06 Rheumatic aortic valve diseases
0.681 0.319 0.000
M77.02 Medial epicondylitis (Upper arm)
0.681 0.319 0.000
M95.0 Acquired deformity of nose
0.681 0.319 0.000
I42.5 Other restrictive cardiomyopathy
0.680 0.320 0.000
I42.4 Endocardial fibroelastosis
0.680 0.320 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.680 0.320 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.679 0.321 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.678 0.322 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.678 0.322 0.000
H30 Chorioretinal inflammation
0.678 0.322 0.000
K85.3 Drug-induced acute pancreatitis
0.678 0.322 0.000
K85.2 Alcohol-induced acute pancreatitis
0.678 0.322 0.000
K85.0 Idiopathic acute pancreatitis
0.678 0.322 0.000
I12.9 Hypertensive renal disease without renal failure
0.677 0.323 0.000
J04 Acute laryngitis and tracheitis
0.676 0.324 0.000
H35.7 Separation of retinal layers
0.676 0.324 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.676 0.324 0.000
A41 Other septicaemia
0.675 0.325 0.000
K81 Cholecystitis
0.674 0.326 0.000
I13 Hypertensive heart and renal disease
0.674 0.326 0.000
M67 Other disorders of synovium and tendon
0.674 0.326 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.673 0.327 0.000
E66.9 Obesity, unspecified
0.673 0.327 0.000
K83.8 Other specified diseases of biliary tract
0.673 0.327 0.000
B35-B49 Mycoses
0.673 0.327 0.000
H34.1 Central retinal artery occlusion
0.672 0.328 0.000
I33 Acute and subacute endocarditis
0.672 0.328 0.000
H10-H13 Disorders of conjunctiva
0.670 0.330 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.670 0.330 0.000
I49.2 Junctional premature depolarisation
0.668 0.332 0.000
K86.3 Pseudocyst of pancreas
0.668 0.332 0.000
I51.6 Cardiovascular disease, unspecified
0.668 0.332 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.668 0.332 0.000
M77.9 Enthesopathy, unspecified
0.667 0.333 0.000
C92 Myeloid leukaemia
0.667 0.333 0.000
I51.4 Myocarditis, unspecified
0.666 0.334 0.000
E83 Disorders of mineral metabolism
0.666 0.334 0.000
H53.6 Night blindness
0.665 0.334 0.000
H53.5 Colour vision deficiencies
0.665 0.334 0.000
H53.3 Other disorders of binocular vision
0.665 0.334 0.000
I31 Other diseases of pericardium
0.665 0.335 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.665 0.335 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.664 0.336 0.000
E10.8 With unspecified complications
0.663 0.337 0.000
M06.3 Rheumatoid nodule
0.662 0.338 0.000
K82.2 Perforation of gallbladder
0.661 0.339 0.000
M14.6 Neuropathic arthropathy
0.661 0.339 0.000
A80-A89 Viral infections of the central nervous system
0.660 0.340 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.660 0.340 0.000
E80.4 Gilbert's syndrome
0.658 0.342 0.000
N27 Small kidney of unknown cause
0.656 0.344 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.655 0.345 0.000
E21.0 Primary hyperparathyroidism
0.655 0.345 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.655 0.345 0.000
I25.4 Coronary artery aneurysm
0.654 0.346 0.000
M99 Biomechanical lesions, not elsewhere classified
0.654 0.346 0.000
I05 Rheumatic mitral valve diseases
0.654 0.346 0.000
J12 Viral pneumonia, not elsewhere classified
0.652 0.348 0.000
I38 Endocarditis, valve unspecified
0.651 0.349 0.000
I34 Nonrheumatic mitral valve disorders
0.651 0.349 0.000
E10.3 With ophthalmic complications
0.650 0.350 0.000
I25.5 Ischaemic cardiomyopathy
0.649 0.350 0.000
I08.9 Multiple valve disease, unspecified
0.649 0.351 0.000
J17.2 Pneumonia in mycoses
0.649 0.351 0.000
E21.3 Hyperparathyroidism, unspecified
0.649 0.351 0.000
J06.9 Acute upper respiratory infection, unspecified
0.648 0.352 0.000
K82.4 Cholesterolosis of gallbladder
0.647 0.353 0.000
J60-J70 Lung diseases due to external agents
0.646 0.354 0.000
M45-M49 Spondylopathies
0.643 0.357 0.000
I51.5 Myocardial degeneration
0.643 0.357 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.643 0.357 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.642 0.358 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.641 0.358 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.641 0.359 0.000
M12 Other specific arthropathies
0.640 0.360 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.640 0.360 0.000
M08 Juvenile arthritis
0.640 0.360 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.640 0.360 0.000
M90.7 Fracture of bone in neoplastic disease
0.639 0.361 0.000
H20 Iridocyclitis
0.637 0.363 0.000
M95.4 Acquired deformity of chest and rib
0.636 0.364 0.000
E78.2 Mixed hyperlipidaemia
0.635 0.364 0.000
I11 Hypertensive heart disease
0.635 0.365 0.000
A40 Streptococcal septicaemia
0.632 0.368 0.000
E13 Other specified diabetes mellitus
0.632 0.368 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.631 0.369 0.000
C15-C26 Malignant neoplasms of digestive organs
0.631 0.369 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.631 0.369 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.630 0.370 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.629 0.371 0.000
N06 Isolated proteinuria with specified morphological lesion
0.629 0.371 0.000
N01 Rapidly progressive nephritic syndrome
0.629 0.371 0.000
N00 Acute nephritic syndrome
0.629 0.371 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.628 0.372 0.000
M66 Spontaneous rupture of synovium and tendon
0.628 0.372 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.627 0.373 0.000
K83.9 Disease of biliary tract, unspecified
0.627 0.373 0.000
N05.2 Diffuse membranous glomerulonephritis
0.627 0.373 0.000
E73.8 Other lactose intolerance
0.625 0.375 0.000
E73.1 Secondary lactase deficiency
0.625 0.375 0.000
E73.0 Congenital lactase deficiency
0.625 0.375 0.000
I15.8 Other secondary hypertension
0.624 0.375 0.000
I15.2 Hypertension secondary to endocrine disorders
0.624 0.375 0.000
H35.3 Degeneration of macula and posterior pole
0.624 0.376 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.623 0.377 0.000
J90 Pleural effusion, not elsewhere classified
0.623 0.377 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.623 0.377 0.000
I09 Other rheumatic heart diseases
0.622 0.378 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.622 0.378 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.621 0.379 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.621 0.379 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.620 0.380 0.000
D38.1 Trachea, bronchus and lung
0.620 0.380 0.000
H31.8 Other specified disorders of choroid
0.618 0.381 0.000
M76 Enthesopathies of lower limb, excluding foot
0.618 0.382 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.618 0.382 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.618 0.382 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.618 0.382 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.618 0.382 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.616 0.384 0.000
N05.1 Focal and segmental glomerular lesions
0.616 0.384 0.000
I51.7 Cardiomegaly
0.614 0.386 0.000
M46 Other inflammatory spondylopathies
0.614 0.386 0.000
K82.9 Disease of gallbladder, unspecified
0.612 0.388 0.000
J41 Simple and mucopurulent chronic bronchitis
0.611 0.388 0.000
I28 Other diseases of pulmonary vessels
0.611 0.389 0.000
E88.3 Tumour lysis syndrome
0.611 0.389 0.000
E55 Vitamin D deficiency
0.611 0.389 0.000
N99-N99 Other disorders of the genitourinary system
0.611 0.389 0.000
H31.0 Chorioretinal scars
0.610 0.389 0.000
M71 Other bursopathies
0.609 0.391 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.609 0.391 0.000
H35.5 Hereditary retinal dystrophy
0.609 0.391 0.000
D37.7 Other digestive organs
0.608 0.392 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.607 0.393 0.000
I49.9 Cardiac arrhythmia, unspecified
0.606 0.394 0.000
M89 Other disorders of bone
0.605 0.395 0.000
C10 Malignant neoplasm of oropharynx
0.605 0.395 0.000
E10.7 With multiple complications
0.605 0.395 0.000
E10.6 With other specified complications
0.605 0.395 0.000
M06.4 Inflammatory polyarthropathy
0.605 0.395 0.000
H34.9 Retinal vascular occlusion, unspecified
0.604 0.396 0.000
H34.0 Transient retinal artery occlusion
0.604 0.396 0.000
M60 Myositis
0.604 0.396 0.000
E11.5 With peripheral circulatory complications
0.604 0.396 0.000
I49.1 Atrial premature depolarisation
0.603 0.397 0.000
K83.1 Obstruction of bile duct
0.603 0.397 0.000
K81.1 Chronic cholecystitis
0.603 0.397 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.602 0.398 0.000
H31.1 Choroidal degeneration
0.601 0.398 0.000
C92.0 Acute myeloid leukaemia
0.601 0.399 0.000
I46 Cardiac arrest
0.601 0.399 0.000
N04.1 Focal and segmental glomerular lesions
0.601 0.399 0.000
C88 Malignant immunoproliferative diseases
0.600 0.400 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.600 0.400 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.600 0.400 0.000
B50-B64 Protozoal diseases
0.600 0.400 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.600 0.400 0.000
A75-A79 Rickettsioses
0.600 0.400 0.000
A70-A74 Other diseases caused by chlamydiae
0.600 0.400 0.000
A65-A69 Other spirochaetal diseases
0.600 0.400 0.000
A20-A28 Certain zoonotic bacterial diseases
0.600 0.400 0.000
A15-A19 Tuberculosis
0.600 0.400 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.599 0.401 0.000
J09 Influenza due to certain identified influenza virus
0.599 0.401 0.000
N05.8 Other
0.599 0.401 0.000
A48 Other bacterial diseases, not elsewhere classified
0.598 0.402 0.000
M88 Paget's disease of bone [osteitis deformans]
0.597 0.402 0.000
E40-E46 Malnutrition
0.597 0.403 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.597 0.403 0.000
J95-J99 Other diseases of the respiratory system
0.597 0.403 0.000
M07 Psoriatic and enteropathic arthropathies
0.596 0.404 0.000
E28 Ovarian dysfunction
0.596 0.404 0.000
N25.9 Disorder resulting from impaired renal tubular function, unspecified
0.595 0.405 0.000
H20.9 Iridocyclitis, unspecified
0.595 0.405 0.000
A41.8 Other specified septicaemia
0.595 0.405 0.000
E67 Other hyperalimentation
0.595 0.405 0.000
E68 Sequelae of hyperalimentation
0.595 0.405 0.000
D46.4 Refractory anaemia, unspecified
0.594 0.406 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.594 0.406 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.594 0.406 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.594 0.406 0.000
E74.2 Disorders of galactose metabolism
0.594 0.406 0.000
E74.1 Disorders of fructose metabolism
0.594 0.406 0.000
E74.0 Glycogen storage disease
0.594 0.406 0.000
M92 Other juvenile osteochondrosis
0.593 0.407 0.000
M93 Other osteochondropathies
0.592 0.407 0.000
N18.9 Chronic renal failure, unspecified
0.592 0.408 0.000
K82.3 Fistula of gallbladder
0.592 0.408 0.000
K82.0 Obstruction of gallbladder
0.592 0.408 0.000
W50-W64 Exposure to animate mechanical forces
0.592 0.408 0.000
H35.1 Retinopathy of prematurity
0.592 0.408 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.591 0.409 0.000
M86 Osteomyelitis
0.590 0.410 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.590 0.410 0.000
C91.9 Lymphoid leukaemia, unspecified
0.589 0.411 0.000
E10.1 With ketoacidosis
0.589 0.411 0.000
I27.2 Other secondary pulmonary hypertension
0.588 0.412 0.000
E14 Unspecified diabetes mellitus
0.588 0.412 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.588 0.412 0.000
I37.9 Pulmonary valve disorder, unspecified
0.587 0.413 0.000
I37.8 Other pulmonary valve disorders
0.587 0.413 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.587 0.413 0.000
I37.0 Pulmonary valve stenosis
0.587 0.413 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.587 0.413 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.587 0.413 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.587 0.413 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.587 0.413 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.587 0.413 0.000
N02.7 Diffuse crescentic glomerulonephritis
0.586 0.413 0.000
N02.6 Dense deposit disease
0.586 0.413 0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis
0.586 0.413 0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis
0.586 0.413 0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis
0.586 0.413 0.000
N02.2 Diffuse membranous glomerulonephritis
0.586 0.413 0.000
N02.1 Focal and segmental glomerular lesions
0.586 0.413 0.000
N02.0 Minor glomerular abnormality
0.586 0.413 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.586 0.414 0.000
M11.2 Other chondrocalcinosis
0.586 0.414 0.000
W20-W49 Exposure to inanimate mechanical forces
0.586 0.414 0.000
A46 Erysipelas
0.586 0.414 0.000
M00 Pyogenic arthritis
0.586 0.414 0.000
M62.8 Other specified disorders of muscle
0.585 0.415 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.585 0.415 0.000
J05.1 Acute epiglottitis
0.584 0.416 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.583 0.417 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.583 0.417 0.000
M77.5 Other enthesopathy of foot
0.583 0.417 0.000
J10.0 Influenza with pneumonia, influenza virus identified
0.583 0.417 0.000
Chapter XXII Codes for special purposes
0.582 0.417 0.000
D47.2 Monoclonal gammopathy
0.582 0.418 0.000
C25 Malignant neoplasm of pancreas
0.581 0.419 0.000
D00-D09 In situ neoplasms
0.581 0.419 0.000
E10.0 With coma
0.581 0.419 0.000
B44 Aspergillosis
0.580 0.420 0.000
Y86 Sequelae of other accidents
0.579 0.421 0.000
I27.1 Kyphoscoliotic heart disease
0.578 0.421 0.000
E24 Cushing's syndrome
0.578 0.422 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.577 0.423 0.000
M61 Calcification and ossification of muscle
0.577 0.423 0.000
A39 Meningococcal infection
0.576 0.424 0.000
M77.91 Enthesopathy, unspecified (Shoulder region)
0.575 0.425 0.000
M40-M43 Deforming dorsopathies
0.575 0.425 0.000
Y88 Sequelae of surgical and medical care as external cause
0.574 0.426 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.574 0.426 0.000
E80.6 Other disorders of bilirubin metabolism
0.574 0.426 0.000
E80.5 Crigler-Najjar syndrome
0.574 0.426 0.000
E80.3 Defects of catalase and peroxydase
0.574 0.426 0.000
E80.2 Other porphyria
0.574 0.426 0.000
E80.1 Porphyria cutanea tarda
0.574 0.426 0.000
E80.0 Hereditary erythropoietic porphyria
0.574 0.426 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.573 0.427 0.000
M06.8 Other specified rheumatoid arthritis
0.573 0.427 0.000
M06.2 Rheumatoid bursitis
0.573 0.427 0.000
M06.1 Adult-onset Still's disease
0.573 0.427 0.000
C05 Malignant neoplasm of palate
0.572 0.428 0.000
M67.8 Other specified disorders of synovium and tendon
0.571 0.429 0.000
V40-V49 Car occupant injured in transport accident
0.571 0.429 0.000
M77.1 Lateral epicondylitis
0.569 0.431 0.000
W75-W84 Other accidental threats to breathing
0.569 0.431 0.000
I51.8 Other ill-defined heart diseases
0.569 0.431 0.000
H21 Other disorders of iris and ciliary body
0.569 0.431 0.000
H53.9 Visual disturbance, unspecified
0.568 0.432 0.000
C95 Leukaemia of unspecified cell type
0.567 0.433 0.000
H18 Other disorders of cornea
0.567 0.433 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.567 0.433 0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.567 0.433 0.000
H17 Corneal scars and opacities
0.566 0.434 0.000
J11.0 Influenza with pneumonia, virus not identified
0.566 0.434 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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