TreeWAS – Variant ID: rs2853925

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
L40 Psoriasis	0.000	0.001	0.999
L40.5 Arthropathic psoriasis	0.000	0.001	0.999
L40.0 Psoriasis vulgaris	0.000	0.104	0.896
L40.4 Guttate psoriasis	0.000	0.283	0.716
L40.3 Pustulosis palmaris et plantaris	0.000	0.283	0.716
L40.2 Acrodermatitis continua	0.000	0.283	0.716
L40.1 Generalised pustular psoriasis	0.000	0.283	0.716
L40.8 Other psoriasis	0.000	0.321	0.679
K90 Intestinal malabsorption	0.000	0.472	0.528
E03 Other hypothyroidism	0.498	0.502	0.001
K90.9 Intestinal malabsorption, unspecified	0.000	0.563	0.437
L40-L45 Papulosquamous disorders	0.000	0.572	0.428
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.410	0.589	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.622	0.378
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.622	0.378
K90.1 Tropical sprue	0.000	0.622	0.378
K90.8 Other intestinal malabsorption	0.000	0.628	0.372
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.640	0.360
E03.5 Myxoedema coma	0.357	0.643	0.001
E03.4 Atrophy of thyroid (acquired)	0.357	0.643	0.001
E03.3 Postinfectious hypothyroidism	0.357	0.643	0.001
E03.1 Congenital hypothyroidism without goitre	0.357	0.643	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.357	0.643	0.001
E03.8 Other specified hypothyroidism	0.324	0.676	0.001
L43 Lichen planus	0.000	0.679	0.321
L44 Other papulosquamous disorders	0.000	0.693	0.307
L41 Parapsoriasis	0.000	0.693	0.307
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.693	0.307
L42 Pityriasis rosea	0.000	0.704	0.296
L43.8 Other lichen planus	0.000	0.758	0.242
L43.9 Lichen planus, unspecified	0.000	0.767	0.233
L43.3 Subacute (active) lichen planus	0.000	0.770	0.230
L43.2 Lichenoid drug reaction	0.000	0.770	0.230
L43.1 Bullous lichen planus	0.000	0.770	0.230
L43.0 Hypertrophic lichen planus	0.000	0.770	0.230
L41.9 Parapsoriasis, unspecified	0.000	0.780	0.220
L41.8 Other parapsoriasis	0.000	0.780	0.220
L41.5 Retiform parapsoriasis	0.000	0.780	0.220
L41.4 Large plaque parapsoriasis	0.000	0.780	0.220
L41.3 Small plaque parapsoriasis	0.000	0.780	0.220
L41.2 Lymphomatoid papulosis	0.000	0.780	0.220
L41.1 Pityriasis lichenoides chronica	0.000	0.780	0.220
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.780	0.220
L44.9 Papulosquamous disorder, unspecified	0.000	0.780	0.220
L44.8 Other specified papulosquamous disorders	0.000	0.780	0.220
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.780	0.220
L44.3 Lichen ruber moniliformis	0.000	0.780	0.220
L44.2 Lichen striatus	0.000	0.780	0.220
L44.1 Lichen nitidus	0.000	0.780	0.220
L44.0 Pityriasis rubra pilaris	0.000	0.780	0.220
M25.5 Pain in joint	0.000	0.911	0.089
M25.54 Pain in joint (Hand)	0.000	0.913	0.087
M25.51 Pain in joint (Shoulder region)	0.000	0.914	0.086
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.919	0.081
M25.59 Pain in joint (Site unspecified)	0.000	0.922	0.078
M25.58 Pain in joint (Other)	0.000	0.927	0.073
I84.9 Unspecified haemorrhoids without complication	0.073	0.927	0.000
M25 Other joint disorders, not elsewhere classified	0.000	0.928	0.072
M25.9 Joint disorder, unspecified	0.000	0.933	0.067
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.936	0.064
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.937	0.063
M25.57 Pain in joint (Ankle and foot)	0.000	0.938	0.062
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.939	0.061
M25.50 Pain in joint (Multiple sites)	0.000	0.939	0.061
M25.56 Pain in joint (Lower leg)	0.000	0.940	0.060
M25.7 Osteophyte	0.000	0.940	0.060
M25.52 Pain in joint (Upper arm)	0.000	0.944	0.056
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.945	0.055
M25.53 Pain in joint (Forearm)	0.000	0.947	0.053
M25.2 Flail joint	0.000	0.948	0.051
M25.1 Fistula of joint	0.000	0.948	0.051
M25.71 Osteophyte (Shoulder region)	0.000	0.949	0.051
M25.8 Other specified joint disorders	0.000	0.951	0.049
M25.74 Osteophyte (Hand)	0.000	0.951	0.049
M25.0 Haemarthrosis	0.000	0.951	0.049
M25.77 Osteophyte (Ankle and foot)	0.000	0.951	0.049
K90-K93 Other diseases of the digestive system	0.000	0.951	0.048
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.952	0.048
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.952	0.048
M25.98 Joint disorder, unspecified (Other)	0.000	0.952	0.048
M25.94 Joint disorder, unspecified (Hand)	0.000	0.952	0.048
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.952	0.048
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.952	0.048
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.952	0.048
M25.76 Osteophyte (Lower leg)	0.000	0.952	0.048
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.952	0.048
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.953	0.046
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.954	0.046
M25.84 Other specified joint disorders (Hand)	0.000	0.954	0.046
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.954	0.046
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.954	0.046
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.954	0.046
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.956	0.044
M25.72 Osteophyte (Upper arm)	0.000	0.957	0.043
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.957	0.043
M25.79 Osteophyte (Site unspecified)	0.000	0.957	0.043
M25.73 Osteophyte (Forearm)	0.000	0.957	0.043
M25.70 Osteophyte (Multiple sites)	0.000	0.957	0.043
M25.4 Effusion of joint	0.000	0.960	0.040
M25.3 Other instability of joint	0.000	0.961	0.039
M25.86 Other specified joint disorders (Lower leg)	0.000	0.961	0.039
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.962	0.038
M25.19 Fistula of joint (Site unspecified)	0.000	0.963	0.037
M25.18 Fistula of joint (Other)	0.000	0.963	0.037
M25.17 Fistula of joint (Ankle and foot)	0.000	0.963	0.037
M25.16 Fistula of joint (Lower leg)	0.000	0.963	0.037
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.963	0.037
M25.14 Fistula of joint (Hand)	0.000	0.963	0.037
M25.13 Fistula of joint (Forearm)	0.000	0.963	0.037
M25.12 Fistula of joint (Upper arm)	0.000	0.963	0.037
M25.11 Fistula of joint (Shoulder region)	0.000	0.963	0.037
M25.10 Fistula of joint (Multiple sites)	0.000	0.963	0.037
M25.29 Flail joint (Site unspecified)	0.000	0.963	0.037
M25.28 Flail joint (Other)	0.000	0.963	0.037
M25.27 Flail joint (Ankle and foot)	0.000	0.963	0.037
M25.26 Flail joint (Lower leg)	0.000	0.963	0.037
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.963	0.037
M25.24 Flail joint (Hand)	0.000	0.963	0.037
M25.23 Flail joint (Forearm)	0.000	0.963	0.037
M25.22 Flail joint (Upper arm)	0.000	0.963	0.037
M25.21 Flail joint (Shoulder region)	0.000	0.963	0.037
M25.20 Flail joint (Multiple sites)	0.000	0.963	0.037
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.963	0.037
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.964	0.035
M25.82 Other specified joint disorders (Upper arm)	0.000	0.964	0.035
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.964	0.035
M25.09 Haemarthrosis (Site unspecified)	0.000	0.965	0.035
M25.08 Haemarthrosis (Other)	0.000	0.965	0.035
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.965	0.035
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.965	0.035
M25.04 Haemarthrosis (Hand)	0.000	0.965	0.035
M25.03 Haemarthrosis (Forearm)	0.000	0.965	0.035
M25.02 Haemarthrosis (Upper arm)	0.000	0.965	0.035
M25.01 Haemarthrosis (Shoulder region)	0.000	0.965	0.035
M25.00 Haemarthrosis (Multiple sites)	0.000	0.965	0.035
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.965	0.035
M25.46 Effusion of joint (Lower leg)	0.000	0.965	0.035
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.966	0.033
M25.06 Haemarthrosis (Lower leg)	0.000	0.967	0.033
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.967	0.032
S64.4 Injury of digital nerve of other finger	0.032	0.968	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.969	0.031
M25.83 Other specified joint disorders (Forearm)	0.000	0.969	0.031
M25.43 Effusion of joint (Forearm)	0.000	0.969	0.031
E00-E07 Disorders of thyroid gland	0.027	0.971	0.002
M25.49 Effusion of joint (Site unspecified)	0.000	0.971	0.029
M25.48 Effusion of joint (Other)	0.000	0.971	0.029
M25.41 Effusion of joint (Shoulder region)	0.000	0.971	0.029
M25.36 Other instability of joint (Lower leg)	0.000	0.971	0.029
M25.88 Other specified joint disorders (Other)	0.000	0.971	0.028
M25.39 Other instability of joint (Site unspecified)	0.000	0.972	0.028
M25.38 Other instability of joint (Other)	0.000	0.972	0.028
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.972	0.028
M25.32 Other instability of joint (Upper arm)	0.000	0.972	0.028
M25.30 Other instability of joint (Multiple sites)	0.000	0.972	0.028
M25.37 Other instability of joint (Ankle and foot)	0.000	0.972	0.028
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.973	0.027
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.974	0.026
M25.31 Other instability of joint (Shoulder region)	0.000	0.974	0.026
M25.42 Effusion of joint (Upper arm)	0.000	0.974	0.025
S64 Injury of nerves at wrist and hand level	0.026	0.974	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.975	0.025
K93.1 Megacolon in Chagas' disease	0.000	0.975	0.025
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.975	0.025
M25.34 Other instability of joint (Hand)	0.000	0.975	0.025
M25.44 Effusion of joint (Hand)	0.000	0.975	0.025
M25.33 Other instability of joint (Forearm)	0.000	0.975	0.025
M25.40 Effusion of joint (Multiple sites)	0.000	0.975	0.024
E07 Other disorders of thyroid	0.021	0.977	0.001
M25.78 Osteophyte (Other)	0.000	0.978	0.022
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.019	0.979	0.002
E00 Congenital iodine-deficiency syndrome	0.019	0.979	0.002
E02 Subclinical iodine-deficiency hypothyroidism	0.019	0.979	0.002
S64.7 Injury of multiple nerves at wrist and hand level	0.021	0.979	0.000
S60-S69 Injuries to the wrist and hand	0.020	0.980	0.000
R94.3 Abnormal results of cardiovascular function studies	0.020	0.980	0.000
M25.47 Effusion of joint (Ankle and foot)	0.000	0.980	0.020
S64.0 Injury of ulnar nerve at wrist and hand level	0.020	0.980	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.020	0.980	0.000
S61.0 Open wound of finger(s) without damage to nail	0.019	0.981	0.000
S64.1 Injury of median nerve at wrist and hand level	0.019	0.981	0.000
S60 Superficial injury of wrist and hand	0.019	0.981	0.000
S61 Open wound of wrist and hand	0.019	0.981	0.000
E07.9 Disorder of thyroid, unspecified	0.019	0.981	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.018	0.981	0.000
S64.8 Injury of other nerves at wrist and hand level	0.018	0.981	0.000
S60.8 Other superficial injuries of wrist and hand	0.018	0.982	0.000
S61.8 Open wound of other parts of wrist and hand	0.018	0.982	0.000
I47 Paroxysmal tachycardia	0.018	0.982	0.000
I47.2 Ventricular tachycardia	0.017	0.983	0.000
I47.1 Supraventricular tachycardia	0.017	0.983	0.000
S68 Traumatic amputation of wrist and hand	0.017	0.983	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.017	0.983	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.983	0.017
E07.1 Dyshormogenetic goitre	0.016	0.983	0.001
E07.0 Hypersecretion of calcitonin	0.016	0.983	0.001
S60.9 Superficial injury of wrist and hand, unspecified	0.016	0.984	0.000
S62 Fracture at wrist and hand level	0.016	0.984	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.014	0.985	0.001
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.014	0.985	0.001
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.014	0.985	0.001
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.014	0.985	0.001
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.014	0.985	0.001
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.014	0.985	0.001
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.014	0.985	0.001
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.014	0.985	0.001
E07.8 Other specified disorders of thyroid	0.014	0.985	0.001
S65 Injury of blood vessels at wrist and hand level	0.015	0.985	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.014	0.986	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.014	0.986	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.014	0.986	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.014	0.986	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.014	0.986	0.000
S60.1 Contusion of finger(s) with damage to nail	0.014	0.986	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.014	0.986	0.000
D41.4 Bladder	0.013	0.987	0.000
I47.0 Reentry ventricular arrhythmia	0.013	0.987	0.000
E06 Thyroiditis	0.011	0.987	0.002
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.987	0.013
S62.7 Multiple fractures of fingers	0.013	0.987	0.000
S67 Crushing injury of wrist and hand	0.013	0.987	0.000
R47.0 Dysphasia and aphasia	0.000	0.987	0.013
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.013	0.987	0.000
J98.4 Other disorders of lung	0.013	0.987	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.987	0.013
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.013	0.987	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.012	0.987	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.012	0.987	0.000
S68.4 Traumatic amputation of hand at wrist level	0.012	0.987	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.012	0.987	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.988	0.012
S62.5 Fracture of thumb	0.012	0.988	0.000
S62.4 Multiple fractures of metacarpal bones	0.012	0.988	0.000
S62.1 Fracture of other carpal bone(s)	0.012	0.988	0.000
S62.3 Fracture of other metacarpal bone	0.012	0.988	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.012	0.988	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.012	0.988	0.000
K91.1 Postgastric surgery syndromes	0.000	0.988	0.011
S60.2 Contusion of other parts of wrist and hand	0.011	0.988	0.000
S60.0 Contusion of finger(s) without damage to nail	0.011	0.989	0.000
K91.5 Postcholecystectomy syndrome	0.000	0.989	0.011
S65.1 Injury of radial artery at wrist and hand level	0.011	0.989	0.000
S62.70 Multiple fractures of fingers (closed)	0.011	0.989	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.011	0.989	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.011	0.989	0.000
S62.2 Fracture of first metacarpal bone	0.011	0.989	0.000
S65.5 Injury of blood vessel(s) of other finger	0.011	0.989	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.011	0.989	0.000
M20-M25 Other joint disorders	0.000	0.989	0.011
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.011	0.989	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.011	0.989	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.011	0.989	0.000
S65.4 Injury of blood vessel(s) of thumb	0.011	0.989	0.000
S65.3 Injury of deep palmar arch	0.011	0.989	0.000
S65.2 Injury of superficial palmar arch	0.011	0.989	0.000
S64.3 Injury of digital nerve of thumb	0.010	0.989	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.011	0.989	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.010	0.989	0.000
S69 Other and unspecified injuries of wrist and hand	0.010	0.989	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.010	0.989	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.010	0.990	0.000
S63.1 Dislocation finger	0.010	0.990	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.010	0.990	0.000
S63.2 Multiple dislocations of fingers	0.010	0.990	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.010	0.990	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.010	0.990	0.000
S63.5 Sprain and strain of wrist	0.010	0.990	0.000
S63.0 Dislocation of wrist	0.010	0.990	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.010	0.990	0.000
C71.9 Brain, unspecified	0.010	0.990	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.990	0.010
D75 Other diseases of blood and blood-forming organs	0.000	0.990	0.010
S65.0 Injury of ulnar artery at wrist and hand level	0.010	0.990	0.000
S62.6 Fracture of other finger	0.010	0.990	0.000
S62.50 Fracture of thumb (closed)	0.010	0.990	0.000
E06.5 Other chronic thyroiditis	0.008	0.990	0.002
E06.4 Drug-induced thyroiditis	0.008	0.990	0.002
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.008	0.990	0.002
E06.1 Subacute thyroiditis	0.008	0.990	0.002
E06.0 Acute thyroiditis	0.008	0.990	0.002
C71.0 Cerebrum, except lobes and ventricles	0.010	0.990	0.000
S62.71 Multiple fractures of fingers (open)	0.009	0.990	0.000
S61.7 Multiple open wounds of wrist and hand	0.009	0.990	0.000
M21 Other acquired deformities of limbs	0.000	0.991	0.009
M24 Other specific joint derangements	0.000	0.991	0.009
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.991	0.009
C71 Malignant neoplasm of brain	0.009	0.991	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.991	0.009
S62.31 Fracture of other metacarpal bone (open)	0.009	0.991	0.000
M24.0 Loose body in joint	0.000	0.991	0.009
M31 Other necrotising vasculopathies	0.000	0.991	0.009
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.009	0.991	0.000
D75.2 Essential thrombocytosis	0.000	0.991	0.009
M13.99 Arthritis, unspecified (Site unspecified)	0.000	0.991	0.009
M32 Systemic lupus erythematosus	0.000	0.991	0.009
S62.41 Multiple fractures of metacarpal bones (open)	0.009	0.991	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.009	0.991	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.009	0.991	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.009	0.991	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.991	0.009
I42.8 Other cardiomyopathies	0.009	0.991	0.000
I49.5 Sick sinus syndrome	0.009	0.991	0.000
M34 Systemic sclerosis	0.000	0.991	0.009
I49 Other cardiac arrhythmias	0.009	0.991	0.000
M24.02 Loose body in joint (Upper arm)	0.000	0.991	0.008
M24.1 Other articular cartilage disorders	0.000	0.991	0.009
M21.3 Wrist or foot drop (acquired)	0.000	0.992	0.008
D72 Other disorders of white blood cells	0.000	0.992	0.008
S61.9 Open wound of wrist and hand, part unspecified	0.008	0.992	0.000
D72.8 Other specified disorders of white blood cells	0.000	0.992	0.008
D70 Agranulocytosis	0.000	0.992	0.008
M21.1 Varus deformity, not elsewhere classified	0.000	0.992	0.008
K91.4 Colostomy and enterostomy malfunction	0.000	0.992	0.008
D73 Diseases of spleen	0.000	0.992	0.008
M30 Polyarteritis nodosa and related conditions	0.000	0.992	0.008
I49.8 Other specified cardiac arrhythmias	0.008	0.992	0.000
C71.2 Temporal lobe	0.008	0.992	0.000
M31.6 Other giant cell arteritis	0.000	0.992	0.008
S62.30 Fracture of other metacarpal bone (closed)	0.008	0.992	0.000
S62.21 Fracture of first metacarpal bone (open)	0.008	0.992	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.992	0.008
S69.7 Multiple injuries of wrist and hand	0.008	0.992	0.000
I42 Cardiomyopathy	0.008	0.992	0.000
M24.01 Loose body in joint (Shoulder region)	0.000	0.992	0.008
D73.0 Hyposplenism	0.000	0.992	0.008
S62.51 Fracture of thumb (open)	0.008	0.992	0.000
C77.2 Intra-abdominal lymph nodes	0.008	0.992	0.000
D75.1 Secondary polycythaemia	0.000	0.992	0.008
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.992	0.008
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.992	0.008
D12.8 Rectum	0.008	0.992	0.000
M33 Dermatopolymyositis	0.000	0.992	0.008
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.008	0.992	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.007	0.992	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.992	0.008
I46.0 Cardiac arrest with successful resuscitation	0.008	0.992	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.992	0.007
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.992	0.007
S61.1 Open wound of finger(s) with damage to nail	0.007	0.993	0.000
M21.0 Valgus deformity, not elsewhere classified	0.000	0.993	0.007
S69.8 Other specified injuries of wrist and hand	0.007	0.993	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.007	0.993	0.000
I49.3 Ventricular premature depolarisation	0.007	0.993	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.993	0.007
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.007	0.993	0.000
C71.3 Parietal lobe	0.007	0.993	0.000
E06.3 Autoimmune thyroiditis	0.006	0.993	0.002
I42.6 Alcoholic cardiomyopathy	0.007	0.993	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.993	0.007
M21.4 Flat foot [pes planus] (acquired)	0.000	0.993	0.007
M34.9 Systemic sclerosis, unspecified	0.000	0.993	0.007
I30-I52 Other forms of heart disease	0.007	0.993	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.993	0.007
S62.20 Fracture of first metacarpal bone (closed)	0.007	0.993	0.000
M24.6 Ankylosis of joint	0.000	0.993	0.007
M21.9 Acquired deformity of limb, unspecified	0.000	0.993	0.007
M21.8 Other specified acquired deformities of limbs	0.000	0.993	0.007
M21.7 Unequal limb length (acquired)	0.000	0.993	0.007
E06.9 Thyroiditis, unspecified	0.004	0.993	0.003
E66.8 Other obesity	0.000	0.993	0.007
M24.9 Joint derangement, unspecified	0.000	0.993	0.007
I50 Heart failure	0.007	0.993	0.000
I50.0 Congestive heart failure	0.007	0.993	0.000
D74 Methaemoglobinaemia	0.000	0.993	0.007
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.993	0.007
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.993	0.007
I49.0 Ventricular fibrillation and flutter	0.007	0.993	0.000
K92.8 Other specified diseases of digestive system	0.000	0.993	0.007
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.993	0.007
I46 Cardiac arrest	0.007	0.993	0.000
R03.1 Nonspecific low blood-pressure reading	0.000	0.993	0.007
C71.4 Occipital lobe	0.007	0.993	0.000
D75.0 Familial erythrocytosis	0.000	0.993	0.007
C71.7 Brain stem	0.007	0.993	0.000
C71.6 Cerebellum	0.007	0.993	0.000
C71.5 Cerebral ventricle	0.007	0.993	0.000
E04 Other non-toxic goitre	0.006	0.993	0.001
I49.4 Other and unspecified premature depolarisation	0.007	0.993	0.000
S63.6 Sprain and strain of finger(s)	0.007	0.993	0.000
S62.61 Fracture of other finger (open)	0.007	0.993	0.000
K92 Other diseases of digestive system	0.000	0.993	0.007
M24.09 Loose body in joint (Site unspecified)	0.000	0.993	0.007
M24.08 Loose body in joint (Other)	0.000	0.993	0.007
M24.06 Loose body in joint-Lower leg	0.000	0.993	0.007
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.993	0.007
M24.04 Loose body in joint (Hand)	0.000	0.993	0.007
M24.03 Loose body in joint (Forearm)	0.000	0.993	0.007
M24.00 Loose body in joint (Multiple sites)	0.000	0.993	0.007
I42.4 Endocardial fibroelastosis	0.007	0.993	0.000
M31.8 Other specified necrotising vasculopathies	0.000	0.993	0.007
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.993	0.007
M31.2 Lethal midline granuloma	0.000	0.993	0.007
M31.1 Thrombotic microangiopathy	0.000	0.993	0.007
M31.0 Hypersensitivity angiitis	0.000	0.993	0.007
E05 Thyrotoxicosis [hyperthyroidism]	0.004	0.993	0.003
M21.6 Other acquired deformities of ankle and foot	0.000	0.993	0.006
M24.2 Disorder of ligament	0.000	0.993	0.007
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.993	0.006
M32.8 Other forms of systemic lupus erythematosus	0.000	0.993	0.006
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.993	0.006
I50.1 Left ventricular failure	0.007	0.993	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.000	0.993	0.006
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.994	0.006
M34.0 Progressive systemic sclerosis	0.000	0.994	0.006
M34.8 Other forms of systemic sclerosis	0.000	0.994	0.006
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.994	0.006
I49.2 Junctional premature depolarisation	0.006	0.994	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.994	0.006
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.994	0.006
M24.18 Other articular cartilage disorders (Other)	0.000	0.994	0.006
M24.14 Other articular cartilage disorders (Hand)	0.000	0.994	0.006
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.994	0.006
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.994	0.006
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.994	0.006
D72.9 Disorder of white blood cells, unspecified	0.000	0.994	0.006
D72.0 Genetic anomalies of leukocytes	0.000	0.994	0.006
K91.3 Postoperative intestinal obstruction	0.000	0.994	0.006
M24.7 Protrusio acetabuli	0.000	0.994	0.006
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.994	0.006
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.994	0.006
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.994	0.006
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.994	0.006
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.994	0.006
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.994	0.006
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.994	0.006
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.994	0.006
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.994	0.006
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.994	0.006
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.994	0.006
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.994	0.006
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.994	0.006
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.994	0.006
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.994	0.006
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.994	0.006
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.994	0.006
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.006	0.994	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.994	0.006
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.994	0.006
D73.9 Disease of spleen, unspecified	0.000	0.994	0.006
D73.8 Other diseases of spleen	0.000	0.994	0.006
D73.4 Cyst of spleen	0.000	0.994	0.006
D73.3 Abscess of spleen	0.000	0.994	0.006
D73.2 Chronic congestive splenomegaly	0.000	0.994	0.006
D73.1 Hypersplenism	0.000	0.994	0.006
M31.3 Wegener's granulomatosis	0.000	0.994	0.006
M35 Other systemic involvement of connective tissue	0.000	0.994	0.006
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.994	0.006
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.994	0.006
M30.2 Juvenile polyarteritis	0.000	0.994	0.006
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.994	0.006
I42.9 Cardiomyopathy, unspecified	0.006	0.994	0.000
M34.1 CR(E)ST syndrome	0.000	0.994	0.006
M33.2 Polymyositis	0.000	0.994	0.006
I42.2 Other hypertrophic cardiomyopathy	0.006	0.994	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.994	0.006
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.006	0.994	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.994	0.006
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.994	0.006
M36.3 Arthropathy in other blood disorders	0.000	0.994	0.006
M36.2 Haemophilic arthropathy	0.000	0.994	0.006
M36.1 Arthropathy in neoplastic disease	0.000	0.994	0.006
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.994	0.006
E11.4 With neurological complications	0.000	0.994	0.006
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.994	0.006
I42.7 Cardiomyopathy due to drugs and other external agents	0.006	0.994	0.000
I42.5 Other restrictive cardiomyopathy	0.006	0.994	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.006	0.994	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.994	0.006
M31.9 Necrotising vasculopathy, unspecified	0.000	0.994	0.006
M31.7 Microscopic polyangiitis	0.000	0.994	0.006
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.000	0.994	0.006
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.006	0.994	0.000
M24.07 Loose body in joint (Ankle and foot)	0.000	0.994	0.006
I36 Nonrheumatic tricuspid valve disorders	0.006	0.994	0.000
M33.9 Dermatopolymyositis, unspecified	0.000	0.994	0.006
M33.0 Juvenile dermatomyositis	0.000	0.994	0.006
S62.60 Fracture of other finger (closed)	0.006	0.994	0.000
C71.8 Overlapping lesion of brain	0.006	0.994	0.000
I30 Acute pericarditis	0.006	0.994	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.994	0.006
D76.3 Other histiocytosis syndromes	0.000	0.994	0.006
E66 Obesity	0.000	0.994	0.006
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.000	0.994	0.006
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.994	0.006
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.000	0.994	0.005
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.000	0.994	0.005
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.000	0.994	0.005
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.000	0.994	0.005
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.000	0.994	0.005
C71.1 Frontal lobe	0.006	0.994	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.994	0.005
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.994	0.005
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.994	0.005
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.994	0.005
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.994	0.005
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.994	0.005
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.994	0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations