TreeWAS – Variant ID: rs2857106

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
L40 Psoriasis	1.000	0.000	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	1.000	0.000	0.000
I21 Acute myocardial infarction	1.000	0.000	0.000
I21.9 Acute myocardial infarction, unspecified	1.000	0.000	0.000
E10.3 With ophthalmic complications	0.000	0.001	0.999
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.999	0.001	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.999	0.001	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.996	0.004	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.996	0.004	0.000
I25.1 Atherosclerotic heart disease	0.994	0.006	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.994	0.006	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.993	0.007	0.000
I25.2 Old myocardial infarction	0.992	0.008	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.989	0.011	0.000
E10.1 With ketoacidosis	0.000	0.011	0.989
T42.4 Benzodiazepines	0.989	0.011	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.988	0.012	0.000
I24 Other acute ischaemic heart diseases	0.987	0.013	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.984	0.016	0.000
M07.3 Other psoriatic arthropathies	0.982	0.018	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.976	0.024	0.000
I20 Angina pectoris	0.976	0.024	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.970	0.030	0.000
J45.9 Asthma, unspecified	0.000	0.033	0.967
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.961	0.039	0.000
D86 Sarcoidosis	0.000	0.055	0.945
D86.9 Sarcoidosis, unspecified	0.000	0.058	0.942
D80-D89 Certain disorders involving the immune mechanism	0.000	0.061	0.939
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.062	0.938
I20.0 Unstable angina	0.935	0.065	0.000
C82.0 Small cleaved cell, follicular	0.934	0.066	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.067	0.933
D50-D53 Nutritional anaemias	0.000	0.069	0.931
D69 Purpura and other haemorrhagic conditions	0.000	0.073	0.927
D69.6 Thrombocytopenia, unspecified	0.000	0.080	0.920
D51 Vitamin B12 deficiency anaemia	0.000	0.083	0.917
E10.4 With neurological complications	0.000	0.085	0.915
D86.0 Sarcoidosis of lung	0.000	0.085	0.915
I25.3 Aneurysm of heart	0.907	0.093	0.000
T43.2 Other and unspecified antidepressants	0.905	0.095	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.096	0.904
I21.1 Acute transmural myocardial infarction of inferior wall	0.892	0.108	0.000
I20.1 Angina pectoris with documented spasm	0.891	0.109	0.000
I21.4 Acute subendocardial myocardial infarction	0.881	0.119	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.881	0.119	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.878	0.122	0.000
I24.8 Other forms of acute ischaemic heart disease	0.870	0.130	0.000
C82.2 Large cell, follicular	0.870	0.130	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.868	0.132	0.000
I23 Certain current complications following acute myocardial infarction	0.866	0.134	0.000
E10.0 With coma	0.000	0.135	0.865
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.862	0.138	0.000
C85.1 B-cell lymphoma, unspecified	0.860	0.140	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.855	0.145	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.853	0.147	0.000
L40.1 Generalised pustular psoriasis	0.849	0.151	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.845	0.155	0.000
C82.3 Follicular lymphoma grade IIIa	0.842	0.158	0.000
D50 Iron deficiency anaemia	0.000	0.162	0.838
T43.5 Other and unspecified antipsychotics and neuroleptics	0.834	0.166	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.834	0.166	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.832	0.168	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.832	0.168	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.829	0.171	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.828	0.172	0.000
I25.5 Ischaemic cardiomyopathy	0.824	0.176	0.000
E10.8 With unspecified complications	0.000	0.176	0.824
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.817	0.183	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.813	0.187	0.000
L40.4 Guttate psoriasis	0.809	0.190	0.000
E10.2 With renal complications	0.000	0.204	0.796
I20.9 Angina pectoris, unspecified	0.793	0.207	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.793	0.207	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.792	0.208	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.215	0.785
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.784	0.216	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.782	0.218	0.000
E10.6 With other specified complications	0.000	0.225	0.775
D86.8 Sarcoidosis of other and combined sites	0.000	0.225	0.775
C82.4 Follicular lymphoma grade IIIb	0.772	0.228	0.000
D50.9 Iron deficiency anaemia, unspecified	0.000	0.231	0.769
M07.34 Other psoriatic arthropathies (Hand)	0.769	0.231	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.764	0.236	0.000
D68 Other coagulation defects	0.000	0.237	0.763
C82.1 Mixed small cleaved and large cell, follicular	0.757	0.243	0.000
L40.0 Psoriasis vulgaris	0.755	0.245	0.000
D50.8 Other iron deficiency anaemias	0.000	0.252	0.748
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.745	0.255	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.255	0.744
D52 Folate deficiency anaemia	0.000	0.256	0.744
D69.5 Secondary thrombocytopenia	0.000	0.262	0.738
I22 Subsequent myocardial infarction	0.737	0.263	0.000
T42.1 Iminostilbenes	0.728	0.272	0.000
T36 Poisoning by systemic antibiotics	0.728	0.272	0.000
L40.8 Other psoriasis	0.717	0.283	0.000
E10.7 With multiple complications	0.000	0.283	0.717
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.717	0.283	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.716	0.284	0.000
T42.3 Barbiturates	0.716	0.284	0.000
T42.2 Succinimides and oxazolidinediones	0.716	0.284	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.716	0.284	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.716	0.284	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.716	0.284	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.716	0.284	0.000
C82.6 Cutaneous follicle centre lymphoma	0.714	0.285	0.000
C82.5 Diffuse follicle centre lymphoma	0.714	0.285	0.000
T50.8 Diagnostic agents	0.714	0.286	0.000
T50.7 Analeptics and opioid receptor antagonists	0.714	0.286	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.714	0.286	0.000
T50.5 Appetite depressants	0.714	0.286	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.714	0.286	0.000
T50.1 Loop [high-ceiling] diuretics	0.714	0.286	0.000
T50.0 Mineralocorticoids and their antagonists	0.714	0.286	0.000
T50.4 Drugs affecting uric acid metabolism	0.713	0.287	0.000
D69.4 Other primary thrombocytopenia	0.000	0.289	0.711
I24.1 Dressler's syndrome	0.708	0.292	0.000
M07.38 Other psoriatic arthropathies (Other)	0.704	0.296	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.704	0.296	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.704	0.296	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.704	0.296	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.704	0.296	0.000
T38.1 Thyroid hormones and substitutes	0.697	0.303	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.305	0.695
T42.0 Hydantoin derivatives	0.693	0.307	0.000
D55-D59 Haemolytic anaemias	0.000	0.309	0.691
T43.9 Psychotropic drug, unspecified	0.689	0.311	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.689	0.311	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.689	0.311	0.000
C95 Leukaemia of unspecified cell type	0.684	0.316	0.000
J45 Asthma	0.000	0.317	0.683
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.323	0.677
D66 Hereditary factor VIII deficiency	0.000	0.323	0.677
D82 Immunodeficiency associated with other major defects	0.000	0.327	0.673
D81 Combined immunodeficiencies	0.000	0.327	0.673
I23.8 Other current complications following acute myocardial infarction	0.672	0.328	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.671	0.329	0.000
L40-L45 Papulosquamous disorders	0.671	0.329	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.671	0.329	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.670	0.330	0.000
D67 Hereditary factor IX deficiency	0.000	0.331	0.669
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.331	0.669
T43.4 Butyrophenone and thioxanthene neuroleptics	0.666	0.334	0.000
D69.0 Allergic purpura	0.000	0.334	0.666
D69.8 Other specified haemorrhagic conditions	0.000	0.336	0.664
D68.9 Coagulation defect, unspecified	0.000	0.338	0.662
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.343	0.657
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.343	0.657
D51.2 Transcobalamin II deficiency	0.000	0.343	0.657
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.343	0.657
T45.0 Antiallergic and antiemetic drugs	0.655	0.345	0.000
D69.9 Haemorrhagic condition, unspecified	0.000	0.351	0.649
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.644	0.356	0.000
D68.0 Von Willebrand's disease	0.000	0.360	0.640
C90 Multiple myeloma and malignant plasma cell neoplasms	0.636	0.364	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.631	0.368	0.000
C94 Other leukaemias of specified cell type	0.631	0.368	0.000
C86 Other specified types of T/NK-cell lymphoma	0.631	0.368	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.631	0.369	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.629	0.371	0.000
C85.0 Lymphosarcoma	0.629	0.371	0.000
D83 Common variable immunodeficiency	0.000	0.373	0.627
J45.0 Predominantly allergic asthma	0.000	0.375	0.625
I22.1 Subsequent myocardial infarction of inferior wall	0.625	0.375	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.375	0.624
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.623	0.377	0.000
T46.1 Calcium-channel blockers	0.622	0.378	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.622	0.378	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.622	0.378	0.000
T46.7 Peripheral vasodilators	0.622	0.378	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.622	0.378	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.622	0.378	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.622	0.378	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.622	0.378	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.621	0.379	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.621	0.379	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.621	0.379	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.621	0.379	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.621	0.379	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.621	0.379	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.618	0.382	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.618	0.382	0.000
T47.7 Emetics	0.618	0.382	0.000
T47.6 Antidiarrhoeal drugs	0.618	0.382	0.000
T47.5 Digestants	0.618	0.382	0.000
T47.4 Other laxatives	0.618	0.382	0.000
T47.3 Saline and osmotic laxatives	0.618	0.382	0.000
T47.2 Stimulant laxatives	0.618	0.382	0.000
T47.0 Histamine H(2)-receptor antagonists	0.618	0.382	0.000
D86.3 Sarcoidosis of skin	0.000	0.382	0.617
E10.5 With peripheral circulatory complications	0.000	0.385	0.615
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.612	0.388	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.612	0.388	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.612	0.388	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.612	0.388	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.612	0.388	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.612	0.388	0.000
T44.0 Anticholinesterase agents	0.612	0.388	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.611	0.389	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.389	0.611
D68.8 Other specified coagulation defects	0.000	0.391	0.609
T45.5 Anticoagulants	0.606	0.394	0.000
D84 Other immunodeficiencies	0.000	0.395	0.605
T43.6 Psychostimulants with abuse potential	0.604	0.396	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.397	0.603
C93 Monocytic leukaemia	0.602	0.398	0.000
D50.1 Sideropenic dysphagia	0.000	0.399	0.600
T46.4 Angiotensin-converting-enzyme inhibitors	0.600	0.400	0.000
T38.9 Other and unspecified hormone antagonists	0.596	0.404	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.596	0.404	0.000
T38.7 Androgens and anabolic congeners	0.596	0.404	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.596	0.404	0.000
T38.5 Other oestrogens and progestogens	0.596	0.404	0.000
T38.4 Oral contraceptives	0.596	0.404	0.000
T38.2 Antithyroid drugs	0.596	0.404	0.000
T38.0 Glucocorticoids and synthetic analogues	0.596	0.404	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.596	0.404	0.000
D68.5 Primary Thrombophilia	0.000	0.413	0.587
D53 Other nutritional anaemias	0.000	0.418	0.582
D59 Acquired haemolytic anaemia	0.000	0.429	0.571
T45.9 Primarily systemic and haematological agent, unspecified	0.569	0.431	0.000
T45.8 Other primarily systemic and haematological agents	0.569	0.431	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.569	0.431	0.000
T45.6 Fibrinolysis-affecting drugs	0.569	0.431	0.000
T45.4 Iron and its compounds	0.569	0.431	0.000
T45.3 Enzymes, not elsewhere classified	0.569	0.431	0.000
D69.2 Other nonthrombocytopenic purpura	0.000	0.432	0.568
T43.0 Tricyclic and tetracyclic antidepressants	0.568	0.432	0.000
C44 Other malignant neoplasms of skin	0.564	0.436	0.000
T45.2 Vitamins, not elsewhere classified	0.562	0.438	0.000
C44.2 Skin of ear and external auricular canal	0.554	0.446	0.000
C44.3 Skin of other and unspecified parts of face	0.553	0.447	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.453	0.547
D68.1 Hereditary factor XI deficiency	0.000	0.455	0.545
C84 Peripheral and cutaneous T-cell lymphomas	0.543	0.457	0.000
C95.9 Leukaemia, unspecified	0.542	0.458	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.461	0.539
D80 Immunodeficiency with predominantly antibody defects	0.000	0.461	0.538
T36.0 Penicillins	0.534	0.466	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.466	0.534
D89.3 Immune reconstitution syndrome	0.000	0.466	0.534
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.466	0.534
D52.8 Other folate deficiency anaemias	0.000	0.466	0.534
D52.1 Drug-induced folate deficiency anaemia	0.000	0.466	0.534
D52.0 Dietary folate deficiency anaemia	0.000	0.466	0.534
L42 Pityriasis rosea	0.533	0.467	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.532	0.468	0.000
D69.1 Qualitative platelet defects	0.000	0.468	0.531
D89.1 Cryoglobulinaemia	0.000	0.468	0.532
C88 Malignant immunoproliferative diseases	0.523	0.477	0.000
C92 Myeloid leukaemia	0.522	0.477	0.000
T36.9 Systemic antibiotic, unspecified	0.522	0.478	0.000
T36.8 Other systemic antibiotics	0.522	0.478	0.000
T36.7 Antifungal antibiotics, systemically used	0.522	0.478	0.000
T36.6 Rifamycins	0.522	0.478	0.000
T36.5 Aminoglycosides	0.522	0.478	0.000
T36.4 Tetracyclines	0.522	0.478	0.000
T36.3 Macrolides	0.522	0.478	0.000
T36.2 Chloramphenicol group	0.522	0.478	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.522	0.478	0.000
M07 Psoriatic and enteropathic arthropathies	0.521	0.479	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.520	0.480	0.000
C44.4 Skin of scalp and neck	0.518	0.482	0.000
L43 Lichen planus	0.518	0.482	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.514	0.486	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.513	0.486	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.513	0.486	0.000
T37.5 Antiviral drugs	0.513	0.486	0.000
T37.4 Anthelminthics	0.513	0.486	0.000
T37.3 Other antiprotozoal drugs	0.513	0.486	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.513	0.486	0.000
T37.1 Antimycobacterial drugs	0.513	0.486	0.000
T37.0 Sulphonamides	0.513	0.486	0.000
T41.5 Therapeutic gases	0.513	0.486	0.000
T41.4 Anaesthetic, unspecified	0.513	0.486	0.000
T41.3 Local anaesthetics	0.513	0.486	0.000
T41.2 Other and unspecified general anaesthetics	0.513	0.486	0.000
T41.1 Intravenous anaesthetics	0.513	0.486	0.000
T41.0 Inhaled anaesthetics	0.513	0.486	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.513	0.486	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.513	0.486	0.000
T48.5 Anti-common-cold drugs	0.513	0.486	0.000
T48.4 Expectorants	0.513	0.486	0.000
T48.3 Antitussives	0.513	0.486	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.513	0.486	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.513	0.486	0.000
T48.0 Oxytocic drugs	0.513	0.486	0.000
T49.9 Topical agent, unspecified	0.513	0.486	0.000
T49.8 Other topical agents	0.513	0.486	0.000
T49.7 Dental drugs, topically applied	0.513	0.486	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.513	0.486	0.000
T49.5 Ophthalmological drugs and preparations	0.513	0.486	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.513	0.486	0.000
T49.3 Emollients, demulcents and protectants	0.513	0.486	0.000
T49.2 Local astringents and local detergents	0.513	0.486	0.000
T49.1 Antipruritics	0.513	0.486	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.513	0.486	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.512	0.488	0.000
I25.4 Coronary artery aneurysm	0.509	0.490	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.493	0.507
C44.7 Skin of lower limb, including hip	0.503	0.497	0.000
C90.0 Multiple myeloma	0.498	0.502	0.000
D59.1 Other autoimmune haemolytic anaemias	0.000	0.503	0.497
D57 Sickle-cell disorders	0.000	0.504	0.496
D55 Anaemia due to enzyme disorders	0.000	0.504	0.496
C83.3 Large cell (diffuse)	0.491	0.509	0.000
C95.7 Other leukaemia of unspecified cell type	0.490	0.510	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.490	0.510	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.490	0.510	0.000
C95.0 Acute leukaemia of unspecified cell type	0.490	0.510	0.000
J45.8 Mixed asthma	0.000	0.510	0.490
J45.1 Nonallergic asthma	0.000	0.510	0.490
D81.9 Combined immunodeficiency, unspecified	0.000	0.517	0.483
D81.8 Other combined immunodeficiencies	0.000	0.517	0.483
D81.7 Major histocompatibility complex class II deficiency	0.000	0.517	0.483
D81.6 Major histocompatibility complex class I deficiency	0.000	0.517	0.483
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.517	0.483
D81.4 Nezelof's syndrome	0.000	0.517	0.483
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.517	0.483
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.517	0.483
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.517	0.483
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.517	0.483
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.517	0.483
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.517	0.483
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.517	0.483
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.517	0.483
D82.2 Immunodeficiency with short-limbed stature	0.000	0.517	0.483
D82.1 Di George's syndrome	0.000	0.517	0.483
D82.0 Wiskott-Aldrich syndrome	0.000	0.517	0.483
L44 Other papulosquamous disorders	0.481	0.519	0.000
L41 Parapsoriasis	0.481	0.519	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.481	0.519	0.000
K90 Intestinal malabsorption	0.000	0.528	0.472
C91 Lymphoid leukaemia	0.470	0.529	0.001
Chapter II Neoplasms	0.468	0.532	0.000
C44.0 Skin of lip	0.468	0.532	0.000
D56 Thalassaemia	0.000	0.534	0.466
C44.9 Malignant neoplasm of skin, unspecified	0.460	0.540	0.000
I22.8 Subsequent myocardial infarction of other sites	0.459	0.541	0.000
C90.1 Plasma cell leukaemia	0.456	0.544	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.453	0.547	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.453	0.547	0.000
C86.4 Blastic NK-cell lymphoma	0.453	0.547	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.453	0.547	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.453	0.547	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.453	0.547	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.453	0.547	0.000
C94.7 Other specified leukaemias	0.453	0.547	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.453	0.547	0.000
C94.5 Acute myelofibrosis	0.453	0.547	0.000
C94.4 Acute panmyelosis	0.453	0.547	0.000
C94.3 Mast cell leukaemia	0.453	0.547	0.000
C94.2 Acute megakaryoblastic leukaemia	0.453	0.547	0.000
C94.1 Chronic erythraemia	0.453	0.547	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.453	0.547	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.453	0.547	0.000
C96.8 Histiocytic sarcoma	0.453	0.547	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.453	0.547	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.453	0.547	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.453	0.547	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.453	0.547	0.000
C96.3 True histiocytic lymphoma	0.453	0.547	0.000
C96.2 Malignant mast cell tumour	0.453	0.547	0.000
C96.1 Malignant histiocytosis	0.453	0.547	0.000
C96.0 Letterer-Siwe disease	0.453	0.547	0.000
D83.8 Other common variable immunodeficiencies	0.000	0.550	0.450
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.550	0.450
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.550	0.450
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.550	0.450
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.447	0.553	0.000
D68.6 Other Thrombophilia	0.000	0.557	0.442
D58 Other hereditary haemolytic anaemias	0.000	0.558	0.442
C90.3 Solitary plasmacytoma	0.442	0.558	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.438	0.562	0.000
D84.8 Other specified immunodeficiencies	0.000	0.566	0.433
D84.1 Defects in the complement system	0.000	0.566	0.433
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.566	0.433
C93.9 Monocytic leukaemia, unspecified	0.432	0.568	0.000
C93.7 Other monocytic leukaemia	0.432	0.568	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.432	0.568	0.000
C93.2 Subacute monocytic leukaemia	0.432	0.568	0.000
C93.0 Acute monocytic leukaemia	0.432	0.568	0.000
C90.2 Plasmacytoma, extramedullary	0.424	0.576	0.000
L43.9 Lichen planus, unspecified	0.423	0.577	0.000
I20.8 Other forms of angina pectoris	0.420	0.580	0.000
D53.8 Other specified nutritional anaemias	0.000	0.582	0.417
D53.2 Scorbutic anaemia	0.000	0.582	0.417
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.582	0.417
D53.0 Protein deficiency anaemia	0.000	0.582	0.417
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.410	0.590	0.000
D59.8 Other acquired haemolytic anaemias	0.000	0.590	0.409
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.590	0.409
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.590	0.409
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.590	0.409
D59.3 Haemolytic-uraemic syndrome	0.000	0.590	0.409
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.590	0.409
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.590	0.409
C44.8 Overlapping lesion of skin	0.404	0.595	0.000
D83.9 Common variable immunodeficiency, unspecified	0.000	0.596	0.404
C93.1 Chronic monocytic leukaemia	0.403	0.597	0.000
C73 Malignant neoplasm of thyroid gland	0.395	0.605	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.393	0.607	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.389	0.610	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.389	0.610	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.389	0.610	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.389	0.610	0.000
C84.3 Lymphoepithelioid lymphoma	0.389	0.610	0.000
C84.2 T-zone lymphoma	0.389	0.610	0.000
C84.1 Sezary's diease	0.389	0.610	0.000
C84.0 Mycosis fungoides	0.389	0.610	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.389	0.611	0.000
C92.0 Acute myeloid leukaemia	0.389	0.611	0.000
C43 Malignant melanoma of skin	0.388	0.612	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.614	0.386
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.614	0.386
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.614	0.386
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.614	0.386
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.614	0.386
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.614	0.386
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.614	0.386
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.614	0.386
C81 Hodgkin's disease	0.382	0.614	0.004
C92.9 Myeloid leukaemia, unspecified	0.386	0.614	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.615	0.385
C44.5 Skin of trunk	0.384	0.616	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.616	0.383
T40.6 Other and unspecified narcotics	0.383	0.617	0.000
C83.7 Burkitt's tumour	0.381	0.618	0.000
C83.6 Undifferentiated (diffuse)	0.381	0.618	0.000
C83.5 Lymphoblastic (diffuse)	0.381	0.618	0.000
C83.4 Immunoblastic (diffuse)	0.381	0.618	0.000
C83.2 Mixed small and large cell (diffuse)	0.381	0.618	0.000
C91.9 Lymphoid leukaemia, unspecified	0.378	0.622	0.001
C88.9 Malignant immunoproliferative disease, unspecified	0.375	0.625	0.000
C88.7 Other malignant immunoproliferative diseases	0.375	0.625	0.000
C88.3 Immunoproliferative small intestinal disease	0.375	0.625	0.000
C88.2 Gamma heavy chain disease	0.375	0.625	0.000
C88.1 Alpha heavy chain disease	0.375	0.625	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.375	0.625	0.000
C92.7 Other myeloid leukaemia	0.375	0.625	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.375	0.625	0.000
C92.5 Acute myelomonocytic leukaemia	0.375	0.625	0.000
C92.3 Myeloid sarcoma	0.375	0.625	0.000
C92.2 Subacute myeloid leukaemia	0.375	0.625	0.000
M07.6 Other enteropathic arthropathies	0.373	0.626	0.000
M07.5 Arthropathy in ulcerative colitis	0.373	0.626	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.373	0.626	0.000
M07.2 Psoriatic spondylitis	0.373	0.626	0.000
M07.1 Arthritis mutilans	0.373	0.626	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.373	0.626	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.373	0.627	0.000
T40.8 Lysergide [LSD]	0.373	0.627	0.000
T40.7 Cannabis (derivatives)	0.373	0.627	0.000
T40.5 Cocaine	0.373	0.627	0.000
T40.3 Methadone	0.373	0.627	0.000
T40.1 Heroin	0.373	0.627	0.000
T40.0 Opium	0.373	0.627	0.000
C02.1 Border of tongue	0.373	0.627	0.000
L43.3 Subacute (active) lichen planus	0.371	0.629	0.000
L43.2 Lichenoid drug reaction	0.371	0.629	0.000
L43.1 Bullous lichen planus	0.371	0.629	0.000
L43.0 Hypertrophic lichen planus	0.371	0.629	0.000
C92.4 Acute promyelocytic leukaemia	0.369	0.630	0.000
C74 Malignant neoplasm of adrenal gland	0.369	0.631	0.000
D60-D64 Aplastic and other anaemias	0.000	0.633	0.367
K90.9 Intestinal malabsorption, unspecified	0.000	0.634	0.366
D84.9 Immunodeficiency, unspecified	0.000	0.635	0.365
C84.4 Peripheral T-cell lymphoma	0.363	0.637	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.637	0.363
C91.5 Adult T-cell leukaemia	0.358	0.642	0.001
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.644	0.355
D55.8 Other anaemias due to enzyme disorders	0.000	0.644	0.355
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.644	0.355
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.644	0.355
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.644	0.355
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.644	0.355
D57.8 Other sickle-cell disorders	0.000	0.644	0.355
D57.3 Sickle-cell trait	0.000	0.644	0.355
D57.2 Double heterozygous sickling disorders	0.000	0.644	0.355
D57.1 Sickle-cell anaemia without crisis	0.000	0.644	0.355
D57.0 Sickle-cell anaemia with crisis	0.000	0.644	0.355
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.354	0.645	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.353	0.647	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.350	0.650	0.000
C64-C68 Malignant neoplasms of urinary tract	0.350	0.650	0.000
C91.0 Acute lymphoblastic leukaemia	0.347	0.652	0.001
L43.8 Other lichen planus	0.347	0.652	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.346	0.654	0.000
L41.9 Parapsoriasis, unspecified	0.345	0.655	0.000
L41.8 Other parapsoriasis	0.345	0.655	0.000
L41.5 Retiform parapsoriasis	0.345	0.655	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations