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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857126
log Bayes Factor = 28.2214
Chromosome 6   position 32,777,140  (GRCh37) Explore rs2857126 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E20-E35 Disorders of other endocrine glands
0.000 0.001 0.999
L40 Psoriasis
0.000 0.001 0.999
G35 Multiple sclerosis
0.999 0.001 0.000
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
C44.7 Skin of lower limb, including hip
0.000 0.001 0.999
C44.6 Skin of upper limb, including shoulder
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.002 0.998
L40.9 Psoriasis, unspecified
0.000 0.003 0.997
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
C44.3 Skin of other and unspecified parts of face
0.000 0.004 0.996
E23 Hypofunction and other disorders of pituitary gland
0.000 0.014 0.986
L57.0 Actinic keratosis
0.000 0.015 0.985
E27 Other disorders of adrenal gland
0.000 0.022 0.978
C44.4 Skin of scalp and neck
0.000 0.026 0.974
E27.1 Primary adrenocortical insufficiency
0.000 0.058 0.942
E23.7 Disorder of pituitary gland, unspecified
0.000 0.060 0.940
G35-G37 Demyelinating diseases of the central nervous system
0.934 0.066 0.000
C44.2 Skin of ear and external auricular canal
0.000 0.070 0.930
E23.6 Other disorders of pituitary gland
0.000 0.074 0.926
E10.9 Without complications
0.000 0.077 0.923
E10.2 With renal complications
0.000 0.083 0.917
G37 Other demyelinating diseases of central nervous system
0.912 0.088 0.000
E10.5 With peripheral circulatory complications
0.000 0.090 0.910
E10.1 With ketoacidosis
0.000 0.103 0.897
E24 Cushing's syndrome
0.000 0.104 0.896
J45.9 Asthma, unspecified
0.881 0.119 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.876 0.124 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.132 0.868
L40-L45 Papulosquamous disorders
0.000 0.145 0.855
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.162 0.838
E28 Ovarian dysfunction
0.000 0.170 0.830
L40.1 Generalised pustular psoriasis
0.000 0.171 0.829
L40.3 Pustulosis palmaris et plantaris
0.000 0.172 0.828
G37.8 Other specified demyelinating diseases of central nervous system
0.823 0.177 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.180 0.820
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.197 0.803
J45 Asthma
0.799 0.201 0.000
C44.0 Skin of lip
0.000 0.207 0.793
E23.0 Hypopituitarism
0.000 0.214 0.786
E10.0 With coma
0.000 0.220 0.780
J45.0 Predominantly allergic asthma
0.777 0.223 0.000
E06 Thyroiditis
0.000 0.227 0.773
L40.4 Guttate psoriasis
0.000 0.230 0.770
M07.3 Other psoriatic arthropathies
0.000 0.233 0.767
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.237 0.763
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.237 0.763
G36 Other acute disseminated demyelination
0.762 0.238 0.000
E13 Other specified diabetes mellitus
0.000 0.239 0.761
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.240 0.760
E10.4 With neurological complications
0.000 0.243 0.757
E83.1 Disorders of iron metabolism
0.756 0.244 0.000
E29 Testicular dysfunction
0.000 0.248 0.752
L40.0 Psoriasis vulgaris
0.000 0.248 0.752
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.252 0.748
L43 Lichen planus
0.000 0.252 0.748
E24.0 Pituitary-dependent Cushing's disease
0.000 0.259 0.741
E24.2 Drug-induced Cushing's syndrome
0.000 0.261 0.739
E26 Hyperaldosteronism
0.000 0.262 0.737
E21.3 Hyperparathyroidism, unspecified
0.000 0.264 0.736
E11 Non-insulin-dependent diabetes mellitus
0.000 0.279 0.721
E10.7 With multiple complications
0.000 0.283 0.717
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.283 0.716
E32 Diseases of thymus
0.000 0.283 0.716
E31 Polyglandular dysfunction
0.000 0.283 0.716
E30 Disorders of puberty, not elsewhere classified
0.000 0.283 0.716
L40.2 Acrodermatitis continua
0.000 0.283 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.293 0.707
E23.1 Drug-induced hypopituitarism
0.000 0.293 0.707
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.295 0.705
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.296 0.704
E27.5 Adrenomedullary hyperfunction
0.000 0.299 0.701
E27.0 Other adrenocortical overactivity
0.000 0.299 0.701
E05.8 Other thyrotoxicosis
0.000 0.300 0.700
E24.9 Cushing's syndrome, unspecified
0.000 0.301 0.699
E28.2 Polycystic ovarian syndrome
0.000 0.305 0.695
E11.3 With ophthalmic complications
0.000 0.306 0.694
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.306 0.694
E27.9 Disorder of adrenal gland, unspecified
0.000 0.308 0.692
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.313 0.687
E25 Adrenogenital disorders
0.000 0.327 0.673
E34 Other endocrine disorders
0.000 0.330 0.670
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.334 0.666
E40-E46 Malnutrition
0.000 0.335 0.664
E06.3 Autoimmune thyroiditis
0.000 0.336 0.664
E10.6 With other specified complications
0.000 0.344 0.656
E65-E68 Obesity and other hyperalimentation
0.000 0.346 0.654
G37.5 Concentric sclerosis [Balo]
0.654 0.346 0.000
G37.4 Subacute necrotising myelitis
0.654 0.346 0.000
G37.2 Central pontine myelinolysis
0.654 0.346 0.000
G37.1 Central demyelination of corpus callosum
0.654 0.346 0.000
G37.0 Diffuse sclerosis
0.654 0.346 0.000
L43.9 Lichen planus, unspecified
0.000 0.348 0.652
E24.8 Other Cushing's syndrome
0.000 0.358 0.642
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.358 0.642
E24.3 Ectopic ACTH syndrome
0.000 0.358 0.642
E24.1 Nelson's syndrome
0.000 0.358 0.642
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.360 0.640
E70-E90 Metabolic disorders
0.000 0.361 0.639
G36.0 Neuromyelitis optica [Devic]
0.639 0.361 0.000
E23.2 Diabetes insipidus
0.000 0.367 0.632
E27.8 Other specified disorders of adrenal gland
0.000 0.374 0.625
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.376 0.623
E28.3 Primary ovarian failure
0.000 0.381 0.619
E27.2 Addisonian crisis
0.000 0.384 0.616
L44 Other papulosquamous disorders
0.000 0.387 0.613
L41 Parapsoriasis
0.000 0.387 0.613
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.387 0.613
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.389 0.611
J45.8 Mixed asthma
0.611 0.389 0.000
E20 Hypoparathyroidism
0.000 0.390 0.609
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.394 0.606
L57.5 Actinic granuloma
0.000 0.399 0.601
L57.3 Poikiloderma of Civatte
0.000 0.399 0.601
L57.2 Cutis rhomboidalis nuchae
0.000 0.399 0.601
L57.1 Actinic reticuloid
0.000 0.399 0.601
J45.1 Nonallergic asthma
0.596 0.404 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.405 0.595
E28.8 Other ovarian dysfunction
0.000 0.405 0.595
E28.1 Androgen excess
0.000 0.405 0.595
E28.0 Oestrogen excess
0.000 0.405 0.595
E16 Other disorders of pancreatic internal secretion
0.000 0.407 0.593
E11.2 With renal complications
0.000 0.410 0.590
E21.4 Other specified disorders of parathyroid gland
0.000 0.412 0.588
E21.2 Other hyperparathyroidism
0.000 0.416 0.584
E10.8 With unspecified complications
0.000 0.417 0.583
L43.8 Other lichen planus
0.000 0.421 0.579
E13.9 Without complications
0.000 0.421 0.579
E29.1 Testicular hypofunction
0.000 0.425 0.575
E89.0 Postprocedural hypothyroidism
0.000 0.427 0.573
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.572 0.427 0.000
E11.0 With coma
0.000 0.428 0.572
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.432 0.568
E78.2 Mixed hyperlipidaemia
0.000 0.433 0.567
E06.5 Other chronic thyroiditis
0.000 0.433 0.567
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.435 0.565
E04 Other non-toxic goitre
0.000 0.438 0.562
E65 Localised adiposity
0.000 0.439 0.561
E13.3 With ophthalmic complications
0.000 0.440 0.560
E06.9 Thyroiditis, unspecified
0.000 0.443 0.557
E06.4 Drug-induced thyroiditis
0.000 0.446 0.554
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.446 0.554
E06.0 Acute thyroiditis
0.000 0.446 0.554
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.447 0.553
M07.38 Other psoriatic arthropathies (Other)
0.000 0.450 0.550
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.450 0.550
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.450 0.550
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.450 0.550
E26.0 Primary hyperaldosteronism
0.000 0.450 0.550
E34.8 Other specified endocrine disorders
0.000 0.453 0.547
E15 Nondiabetic hypoglycaemic coma
0.000 0.453 0.547
G36.9 Acute disseminated demyelination, unspecified
0.546 0.454 0.000
G36.8 Other specified acute disseminated demyelination
0.546 0.454 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.546 0.454 0.000
E13.8 With unspecified complications
0.000 0.454 0.546
E13.7 With multiple complications
0.000 0.454 0.546
E13.6 With other specified complications
0.000 0.454 0.546
E13.5 With peripheral circulatory complications
0.000 0.454 0.546
E13.4 With neurological complications
0.000 0.454 0.546
E13.2 With renal complications
0.000 0.454 0.546
E13.1 With ketoacidosis
0.000 0.454 0.546
E13.0 With coma
0.000 0.454 0.546
E78.5 Hyperlipidaemia, unspecified
0.000 0.454 0.546
E22 Hyperfunction of pituitary gland
0.000 0.456 0.544
E29.9 Testicular dysfunction, unspecified
0.000 0.461 0.539
E29.8 Other testicular dysfunction
0.000 0.461 0.539
E29.0 Testicular hyperfunction
0.000 0.461 0.539
E78.6 Lipoprotein deficiency
0.000 0.463 0.537
L55 Sunburn
0.000 0.464 0.536
L43.3 Subacute (active) lichen planus
0.000 0.464 0.536
L43.2 Lichenoid drug reaction
0.000 0.464 0.536
L43.1 Bullous lichen planus
0.000 0.464 0.536
L43.0 Hypertrophic lichen planus
0.000 0.464 0.536
E88 Other metabolic disorders
0.000 0.468 0.532
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.468 0.531
E26.9 Hyperaldosteronism, unspecified
0.000 0.471 0.529
E26.8 Other hyperaldosteronism
0.000 0.471 0.529
E26.1 Secondary hyperaldosteronism
0.000 0.471 0.529
L40.8 Other psoriasis
0.000 0.478 0.522
L42 Pityriasis rosea
0.000 0.482 0.518
E11.7 With multiple complications
0.000 0.483 0.517
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.514
E30.8 Other disorders of puberty
0.000 0.486 0.514
E30.1 Precocious puberty
0.000 0.486 0.514
E30.0 Delayed puberty
0.000 0.486 0.514
E31.9 Polyglandular dysfunction, unspecified
0.000 0.486 0.514
E31.8 Other polyglandular dysfunction
0.000 0.486 0.514
E31.1 Polyglandular hyperfunction
0.000 0.486 0.514
E31.0 Autoimmune polyglandular failure
0.000 0.486 0.514
E32.9 Disease of thymus, unspecified
0.000 0.486 0.514
E32.8 Other diseases of thymus
0.000 0.486 0.514
E32.1 Abscess of thymus
0.000 0.486 0.514
E32.0 Persistent hyperplasia of thymus
0.000 0.486 0.514
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.514
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.514
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.513
E04.0 Non-toxic diffuse goitre
0.000 0.498 0.502
E78.1 Pure hyperglyceridaemia
0.000 0.499 0.501
E11.6 With other specified complications
0.000 0.501 0.499
E11.8 With unspecified complications
0.000 0.503 0.497
E79 Disorders of purine and pyrimidine metabolism
0.000 0.503 0.497
L58 Radiodermatitis
0.000 0.508 0.492
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.512 0.488
E25.9 Adrenogenital disorder, unspecified
0.000 0.517 0.483
E25.8 Other adrenogenital disorders
0.000 0.517 0.483
E89.3 Postprocedural hypopituitarism
0.000 0.519 0.481
E34.5 Androgen resistance syndrome
0.000 0.519 0.480
E34.4 Constitutional tall stature
0.000 0.519 0.480
E34.3 Short stature, not elsewhere classified
0.000 0.519 0.480
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.519 0.480
E34.1 Other hypersecretion of intestinal hormones
0.000 0.519 0.480
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.523 0.476
E45 Retarded development following protein-energy malnutrition
0.000 0.523 0.476
E43 Unspecified severe protein-energy malnutrition
0.000 0.523 0.476
E42 Marasmic kwashiorkor
0.000 0.523 0.476
E41 Nutritional marasmus
0.000 0.523 0.476
E40 Kwashiorkor
0.000 0.523 0.476
L10-L14 Bullous disorders
0.000 0.526 0.474
E67 Other hyperalimentation
0.000 0.531 0.469
E68 Sequelae of hyperalimentation
0.000 0.531 0.469
E84 Cystic fibrosis
0.000 0.532 0.468
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.534 0.466
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.536 0.464
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.539 0.461
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.540 0.460
E77 Disorders of glycoprotein metabolism
0.000 0.542 0.458
E76 Disorders of glycosaminoglycan metabolism
0.000 0.542 0.458
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.542 0.458
E70 Disorders of aromatic amino-acid metabolism
0.000 0.542 0.458
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.542 0.458
E16.2 Hypoglycaemia, unspecified
0.000 0.547 0.453
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.552 0.447
E21.0 Primary hyperparathyroidism
0.000 0.553 0.447
E88.3 Tumour lysis syndrome
0.000 0.558 0.442
E07 Other disorders of thyroid
0.000 0.558 0.442
L41.9 Parapsoriasis, unspecified
0.000 0.560 0.439
L41.8 Other parapsoriasis
0.000 0.560 0.439
L41.5 Retiform parapsoriasis
0.000 0.560 0.439
L41.4 Large plaque parapsoriasis
0.000 0.560 0.439
L41.3 Small plaque parapsoriasis
0.000 0.560 0.439
L41.2 Lymphomatoid papulosis
0.000 0.560 0.439
L41.1 Pityriasis lichenoides chronica
0.000 0.560 0.439
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.560 0.439
L44.9 Papulosquamous disorder, unspecified
0.000 0.560 0.439
L44.8 Other specified papulosquamous disorders
0.000 0.560 0.439
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.560 0.439
L44.3 Lichen ruber moniliformis
0.000 0.560 0.439
L44.2 Lichen striatus
0.000 0.560 0.439
L44.1 Lichen nitidus
0.000 0.560 0.439
L44.0 Pityriasis rubra pilaris
0.000 0.560 0.439
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.561 0.439
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.562 0.438
E88.8 Other specified metabolic disorders
0.000 0.563 0.437
E20.1 Pseudohypoparathyroidism
0.000 0.563 0.437
E20.0 Idiopathic hypoparathyroidism
0.000 0.563 0.437
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.566 0.434
E89.5 Postprocedural testicular hypofunction
0.000 0.566 0.434
E89.4 Postprocedural ovarian failure
0.000 0.566 0.434
L57.4 Cutis laxa senilis
0.000 0.568 0.432
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.569 0.431
E34.9 Endocrine disorder, unspecified
0.000 0.571 0.429
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.575 0.425
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.575 0.425
E16.4 Abnormal secretion of gastrin
0.000 0.575 0.425
E16.3 Increased secretion of glucagon
0.000 0.575 0.425
E46 Unspecified protein-energy malnutrition
0.000 0.576 0.424
E06.1 Subacute thyroiditis
0.000 0.578 0.421
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.580 0.420
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.587 0.413
E20.9 Hypoparathyroidism, unspecified
0.000 0.592 0.407
L56.3 Solar urticaria
0.000 0.593 0.407
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.593 0.407
L56.1 Drug photoallergic response
0.000 0.593 0.407
L56.0 Drug phototoxic response
0.000 0.593 0.407
E16.1 Other hypoglycaemia
0.000 0.594 0.406
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.594 0.406
E89.1 Postprocedural hypoinsulinaemia
0.000 0.595 0.405
E88.2 Lipomatosis, not elsewhere classified
0.000 0.596 0.404
C44.9 Malignant neoplasm of skin, unspecified
0.001 0.596 0.403
E04.8 Other specified non-toxic goitre
0.000 0.597 0.403
E78.4 Other hyperlipidaemia
0.000 0.602 0.398
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.605 0.395
E89.2 Postprocedural hypoparathyroidism
0.000 0.607 0.393
E74 Other disorders of carbohydrate metabolism
0.000 0.608 0.392
E72 Other disorders of amino-acid metabolism
0.000 0.608 0.392
E78.3 Hyperchylomicronaemia
0.000 0.610 0.390
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.610 0.390
E22.8 Other hyperfunction of pituitary gland
0.000 0.610 0.390
E22.1 Hyperprolactinaemia
0.000 0.614 0.386
E11.1 With ketoacidosis
0.000 0.614 0.386
E04.2 Non-toxic multinodular goitre
0.000 0.615 0.385
L55.9 Sunburn, unspecified
0.000 0.615 0.384
L55.8 Other sunburn
0.000 0.615 0.384
L55.2 Sunburn of third degree
0.000 0.615 0.384
L55.1 Sunburn of second degree
0.000 0.615 0.384
L55.0 Sunburn of first degree
0.000 0.615 0.384
E11.5 With peripheral circulatory complications
0.000 0.616 0.384
E34.0 Carcinoid syndrome
0.000 0.617 0.383
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.000 0.619 0.381
L59.0 Erythema ab igne [dermatitis ab igne]
0.000 0.619 0.381
E73 Lactose intolerance
0.000 0.619 0.381
E85 Amyloidosis
0.000 0.620 0.380
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.000 0.624 0.376
E20.8 Other hypoparathyroidism
0.000 0.629 0.371
E88.9 Metabolic disorder, unspecified
0.000 0.632 0.368
L56.4 Polymorphous light eruption
0.000 0.632 0.367
E78.8 Other disorders of lipoprotein metabolism
0.000 0.635 0.365
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.638 0.362
E80.4 Gilbert's syndrome
0.000 0.641 0.359
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.644 0.356
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.644 0.356
E79.1 Lesch-Nyhan syndrome
0.000 0.644 0.356
L12 Pemphigoid
0.000 0.647 0.353
L58.1 Chronic radiodermatitis
0.000 0.647 0.353
L58.0 Acute radiodermatitis
0.000 0.647 0.353
C44.5 Skin of trunk
0.000 0.650 0.350
E84.9 Cystic fibrosis, unspecified
0.000 0.654 0.346
E50-E64 Other nutritional deficiencies
0.000 0.656 0.344
E44.1 Mild protein-energy malnutrition
0.000 0.658 0.342
E44.0 Moderate protein-energy malnutrition
0.000 0.658 0.342
L10 Pemphigus
0.000 0.660 0.340
L14 Bullous disorders in diseases classified elsewhere
0.000 0.660 0.340
E67.8 Other specified hyperalimentation
0.000 0.663 0.336
E67.3 Hypervitaminosis D
0.000 0.663 0.336
E67.2 Megavitamin-B6 syndrome
0.000 0.663 0.336
E67.1 Hypercarotenaemia
0.000 0.663 0.336
E67.0 Hypervitaminosis A
0.000 0.663 0.336
E84.8 Cystic fibrosis with other manifestations
0.000 0.664 0.336
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.664 0.336
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.664 0.336
L11 Other acantholytic disorders
0.000 0.664 0.336
E80.6 Other disorders of bilirubin metabolism
0.000 0.664 0.336
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.671 0.329
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.671 0.329
E70.3 Albinism
0.000 0.671 0.329
E70.2 Disorders of tyrosine metabolism
0.000 0.671 0.329
E70.1 Other hyperphenylalaninaemias
0.000 0.671 0.329
E70.0 Classical phenylketonuria
0.000 0.671 0.329
E71.3 Disorders of fatty-acid metabolism
0.000 0.671 0.329
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.671 0.329
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.671 0.329
E71.0 Maple-syrup-urine disease
0.000 0.671 0.329
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.671 0.329
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.671 0.329
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.671 0.329
E76.2 Other mucopolysaccharidoses
0.000 0.671 0.329
E76.1 Mucopolysaccharidosis, type II
0.000 0.671 0.329
E76.0 Mucopolysaccharidosis, type I
0.000 0.671 0.329
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.671 0.329
E77.8 Other disorders of glycoprotein metabolism
0.000 0.671 0.329
E77.1 Defects in glycoprotein degradation
0.000 0.671 0.329
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.671 0.329
E04.9 Non-toxic goitre, unspecified
0.000 0.679 0.321
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.679 0.321
E80.5 Crigler-Najjar syndrome
0.000 0.679 0.321
E80.3 Defects of catalase and peroxydase
0.000 0.679 0.321
E80.0 Hereditary erythropoietic porphyria
0.000 0.679 0.321
E07.1 Dyshormogenetic goitre
0.000 0.683 0.317
E07.0 Hypersecretion of calcitonin
0.000 0.683 0.317
L60-L75 Disorders of skin appendages
0.000 0.683 0.317
E75.6 Lipid storage disorder, unspecified
0.000 0.686 0.314
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.686 0.314
E75.3 Sphingolipidosis, unspecified
0.000 0.686 0.314
E75.1 Other gangliosidosis
0.000 0.686 0.314
E75.0 GM2 gangliosidosis
0.000 0.686 0.314
L13 Other bullous disorders
0.000 0.688 0.311
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.691 0.309
L58.9 Radiodermatitis, unspecified
0.000 0.691 0.308
E75.2 Other sphingolipidosis
0.000 0.693 0.307
E78.0 Pure hypercholesterolaemia
0.000 0.698 0.302
E80.1 Porphyria cutanea tarda
0.000 0.699 0.301
E75.5 Other lipid storage disorders
0.000 0.699 0.301
M07 Psoriatic and enteropathic arthropathies
0.000 0.709 0.291
E85.4 Organ-limited amyloidosis
0.000 0.713 0.287
E07.8 Other specified disorders of thyroid
0.000 0.717 0.283
E11.4 With neurological complications
0.000 0.718 0.282
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.719 0.281
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.719 0.281
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.719 0.281
E74.2 Disorders of galactose metabolism
0.000 0.719 0.281
E74.1 Disorders of fructose metabolism
0.000 0.719 0.281
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.719 0.281
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.719 0.281
E72.5 Disorders of glycine metabolism
0.000 0.719 0.281
E72.4 Disorders of ornithine metabolism
0.000 0.719 0.281
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.719 0.281
E72.2 Disorders of urea cycle metabolism
0.000 0.719 0.281
E03 Other hypothyroidism
0.000 0.722 0.278
E74.0 Glycogen storage disease
0.000 0.722 0.278
L71 Rosacea
0.000 0.724 0.276
E72.0 Disorders of amino-acid transport
0.000 0.724 0.276
E83 Disorders of mineral metabolism
0.074 0.724 0.202
E51 Thiamine deficiency
0.000 0.726 0.274
E22.0 Acromegaly and pituitary gigantism
0.000 0.726 0.274
E73.8 Other lactose intolerance
0.000 0.726 0.273
E73.1 Secondary lactase deficiency
0.000 0.726 0.273
E73.0 Congenital lactase deficiency
0.000 0.726 0.273
E85.9 Amyloidosis, unspecified
0.000 0.727 0.272
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.728 0.272
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.728 0.272
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.728 0.272
L12.9 Pemphigoid, unspecified
0.000 0.730 0.270
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.732 0.268
E11.9 Without complications
0.000 0.735 0.265
E56 Other vitamin deficiencies
0.000 0.742 0.258
E80.2 Other porphyria
0.000 0.743 0.256
L12.8 Other pemphigoid
0.000 0.747 0.253
L12.3 Acquired epidermolysis bullosa
0.000 0.747 0.253
L12.2 Chronic bullous disease of childhood
0.000 0.747 0.253
L68 Hypertrichosis
0.000 0.748 0.252
L12.1 Cicatricial pemphigoid
0.000 0.748 0.252
L12.0 Bullous pemphigoid
0.000 0.750 0.250
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.753 0.247
E50 Vitamin A deficiency
0.000 0.753 0.247
E60 Dietary zinc deficiency
0.000 0.753 0.247
E59 Dietary selenium deficiency
0.000 0.753 0.247
E52 Niacin deficiency [pellagra]
0.000 0.753 0.247
L10.9 Pemphigus, unspecified
0.000 0.756 0.244
L10.8 Other pemphigus
0.000 0.756 0.244
L10.5 Drug-induced pemphigus
0.000 0.756 0.244
L10.4 Pemphigus erythematosus
0.000 0.756 0.244
L10.3 Brazilian pemphigus [fogo selvagem]
0.000 0.756 0.244
L10.2 Pemphigus foliaceus
0.000 0.756 0.244
L10.1 Pemphigus vegetans
0.000 0.756 0.244
L10.0 Pemphigus vulgaris
0.000 0.756 0.244
L11.0 Acquired keratosis follicularis
0.000 0.758 0.242
L50-L54 Urticaria and erythema
0.000 0.758 0.242
L11.9 Acantholytic disorder, unspecified
0.000 0.759 0.241
L11.8 Other specified acantholytic disorders
0.000 0.759 0.241
L66 Cicatricial alopecia [scarring hair loss]
0.000 0.759 0.241
L71.9 Rosacea, unspecified
0.000 0.760 0.240
E55 Vitamin D deficiency
0.000 0.761 0.239
L11.1 Transient acantholytic dermatosis [Grover]
0.000 0.765 0.235
E63 Other nutritional deficiencies
0.000 0.765 0.235
L63 Alopecia areata
0.000 0.769 0.231
E85.8 Other amyloidosis
0.000 0.769 0.231
L75 Apocrine sweat disorders
0.000 0.773 0.227
L74 Eccrine sweat disorders
0.000 0.773 0.227
L67 Hair colour and hair shaft abnormalities
0.000 0.773 0.227
L64 Androgenic alopecia
0.000 0.773 0.227
L62 Nail disorders in diseases classified elsewhere
0.000 0.773 0.227
L60 Nail disorders
0.000 0.774 0.226
E85.3 Secondary systemic amyloidosis
0.000 0.776 0.224
E51.2 Wernicke's encephalopathy
0.000 0.776 0.224
L13.9 Bullous disorder, unspecified
0.000 0.776 0.223
L13.8 Other specified bullous disorders
0.000 0.776 0.223
L13.1 Subcorneal pustular dermatitis
0.000 0.776 0.223
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.777 0.222
E54 Ascorbic acid deficiency
0.000 0.778 0.222
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.780 0.219
E58 Dietary calcium deficiency
0.000 0.784 0.215
L70 Acne
0.000 0.784 0.216
L71.1 Rhinophyma
0.000 0.785 0.215
L60.9 Nail disorder, unspecified
0.000 0.787 0.213
M07.5 Arthropathy in ulcerative colitis
0.000 0.791 0.208
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.791 0.208
M07.2 Psoriatic spondylitis
0.000 0.791 0.208
M07.1 Arthritis mutilans
0.000 0.791 0.208
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.791 0.208
L68.0 Hirsutism
0.000 0.794 0.206
L65 Other nonscarring hair loss
0.000 0.800 0.200
E03.5 Myxoedema coma
0.000 0.800 0.199
E03.4 Atrophy of thyroid (acquired)
0.000 0.800 0.199
E03.3 Postinfectious hypothyroidism
0.000 0.800 0.199
L51 Erythema multiforme
0.000 0.801 0.199
L71.8 Other rosacea
0.000 0.802 0.198
L71.0 Perioral dermatitis
0.000 0.802 0.198

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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