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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857129
log Bayes Factor = 26.2648
Chromosome 6   position 32,776,623  (GRCh37) Explore rs2857129 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
L40 Psoriasis
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.001 0.999
C44 Other malignant neoplasms of skin
0.000 0.001 0.999
E20-E35 Disorders of other endocrine glands
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.002 0.998
C44.7 Skin of lower limb, including hip
0.000 0.003 0.997
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.003 0.997
L40.9 Psoriasis, unspecified
0.000 0.003 0.997
C44.6 Skin of upper limb, including shoulder
0.000 0.004 0.996
C44.3 Skin of other and unspecified parts of face
0.000 0.005 0.995
E05.9 Thyrotoxicosis, unspecified
0.000 0.009 0.991
E23 Hypofunction and other disorders of pituitary gland
0.000 0.019 0.981
C44.4 Skin of scalp and neck
0.000 0.025 0.975
G35-G37 Demyelinating diseases of the central nervous system
0.963 0.037 0.000
E27 Other disorders of adrenal gland
0.000 0.044 0.956
J45.9 Asthma, unspecified
0.952 0.048 0.000
L57.0 Actinic keratosis
0.000 0.049 0.951
G37 Other demyelinating diseases of central nervous system
0.951 0.049 0.000
C44.2 Skin of ear and external auricular canal
0.000 0.058 0.942
E23.7 Disorder of pituitary gland, unspecified
0.000 0.063 0.937
G37.9 Demyelinating disease of central nervous system, unspecified
0.928 0.072 0.000
E10.9 Without complications
0.000 0.075 0.925
E10.2 With renal complications
0.000 0.077 0.923
E10.5 With peripheral circulatory complications
0.000 0.080 0.920
E23.6 Other disorders of pituitary gland
0.000 0.089 0.911
E27.1 Primary adrenocortical insufficiency
0.000 0.093 0.907
E24 Cushing's syndrome
0.000 0.100 0.900
J45 Asthma
0.899 0.101 0.000
E10.1 With ketoacidosis
0.000 0.105 0.895
J45.0 Predominantly allergic asthma
0.885 0.115 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.127 0.873
G37.8 Other specified demyelinating diseases of central nervous system
0.870 0.130 0.000
E28 Ovarian dysfunction
0.000 0.149 0.851
L40.1 Generalised pustular psoriasis
0.000 0.163 0.837
L40.3 Pustulosis palmaris et plantaris
0.000 0.170 0.830
L40-L45 Papulosquamous disorders
0.000 0.172 0.828
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.180 0.820
C44.0 Skin of lip
0.000 0.188 0.812
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.191 0.809
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.198 0.802
E21.3 Hyperparathyroidism, unspecified
0.000 0.210 0.790
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.211 0.788
E10.0 With coma
0.000 0.215 0.785
G36 Other acute disseminated demyelination
0.784 0.216 0.000
L40.4 Guttate psoriasis
0.000 0.228 0.772
L40.0 Psoriasis vulgaris
0.000 0.229 0.771
E10.4 With neurological complications
0.000 0.233 0.767
E26 Hyperaldosteronism
0.000 0.245 0.755
E06 Thyroiditis
0.000 0.245 0.755
E24.0 Pituitary-dependent Cushing's disease
0.000 0.252 0.747
E24.2 Drug-induced Cushing's syndrome
0.000 0.260 0.740
E28.2 Polycystic ovarian syndrome
0.000 0.264 0.736
E13 Other specified diabetes mellitus
0.000 0.267 0.733
E23.0 Hypopituitarism
0.000 0.273 0.727
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.278 0.722
E10.7 With multiple complications
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
C44.8 Overlapping lesion of skin
0.000 0.284 0.716
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.284 0.716
E32 Diseases of thymus
0.000 0.284 0.716
E31 Polyglandular dysfunction
0.000 0.284 0.716
E30 Disorders of puberty, not elsewhere classified
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.715
E24.9 Cushing's syndrome, unspecified
0.000 0.286 0.714
E29 Testicular dysfunction
0.000 0.286 0.714
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.291 0.709
L43 Lichen planus
0.000 0.294 0.706
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.296 0.704
E23.1 Drug-induced hypopituitarism
0.000 0.296 0.704
E34 Other endocrine disorders
0.000 0.305 0.695
E27.9 Disorder of adrenal gland, unspecified
0.000 0.313 0.687
E27.5 Adrenomedullary hyperfunction
0.000 0.314 0.686
E27.0 Other adrenocortical overactivity
0.000 0.314 0.686
J45.8 Mixed asthma
0.685 0.315 0.000
G37.5 Concentric sclerosis [Balo]
0.682 0.318 0.000
G37.4 Subacute necrotising myelitis
0.682 0.318 0.000
G37.2 Central pontine myelinolysis
0.682 0.318 0.000
G37.1 Central demyelination of corpus callosum
0.682 0.318 0.000
G37.0 Diffuse sclerosis
0.682 0.318 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.320 0.680
E25 Adrenogenital disorders
0.000 0.325 0.674
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.330 0.670
J45.1 Nonallergic asthma
0.668 0.332 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.332 0.668
E05.8 Other thyrotoxicosis
0.000 0.333 0.666
E10.6 With other specified complications
0.000 0.338 0.662
E16 Other disorders of pancreatic internal secretion
0.000 0.339 0.661
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.343 0.657
G36.0 Neuromyelitis optica [Devic]
0.655 0.344 0.000
E11.3 With ophthalmic complications
0.000 0.346 0.654
E06.3 Autoimmune thyroiditis
0.000 0.346 0.654
E23.2 Diabetes insipidus
0.000 0.348 0.652
M07.3 Other psoriatic arthropathies
0.000 0.349 0.651
E83.1 Disorders of iron metabolism
0.646 0.354 0.000
E24.8 Other Cushing's syndrome
0.000 0.354 0.645
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.354 0.645
E24.3 Ectopic ACTH syndrome
0.000 0.354 0.645
E24.1 Nelson's syndrome
0.000 0.354 0.645
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.355 0.645
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.355 0.645
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.361 0.639
E28.3 Primary ovarian failure
0.000 0.370 0.630
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.370 0.630
E40-E46 Malnutrition
0.000 0.371 0.629
E21.4 Other specified disorders of parathyroid gland
0.000 0.374 0.626
E21.2 Other hyperparathyroidism
0.000 0.376 0.624
E04 Other non-toxic goitre
0.000 0.377 0.623
E28.9 Ovarian dysfunction, unspecified
0.000 0.390 0.610
E28.8 Other ovarian dysfunction
0.000 0.390 0.610
E28.1 Androgen excess
0.000 0.390 0.610
E28.0 Oestrogen excess
0.000 0.390 0.610
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.607 0.393 0.000
E27.2 Addisonian crisis
0.000 0.397 0.603
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.400 0.600
L44 Other papulosquamous disorders
0.000 0.406 0.594
L41 Parapsoriasis
0.000 0.406 0.594
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.406 0.594
E10.8 With unspecified complications
0.000 0.410 0.590
L43.9 Lichen planus, unspecified
0.000 0.410 0.590
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.410 0.590
L57.5 Actinic granuloma
0.000 0.412 0.588
L57.3 Poikiloderma of Civatte
0.000 0.412 0.588
L57.2 Cutis rhomboidalis nuchae
0.000 0.412 0.588
L57.1 Actinic reticuloid
0.000 0.412 0.588
E27.8 Other specified disorders of adrenal gland
0.000 0.417 0.583
E26.0 Primary hyperaldosteronism
0.000 0.419 0.581
E70-E90 Metabolic disorders
0.000 0.423 0.577
E15 Nondiabetic hypoglycaemic coma
0.000 0.425 0.575
E34.8 Other specified endocrine disorders
0.000 0.425 0.575
E65 Localised adiposity
0.000 0.427 0.573
E20 Hypoparathyroidism
0.000 0.429 0.571
G36.9 Acute disseminated demyelination, unspecified
0.562 0.438 0.000
G36.8 Other specified acute disseminated demyelination
0.562 0.438 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.562 0.438 0.000
E11.2 With renal complications
0.000 0.443 0.557
L43.8 Other lichen planus
0.000 0.444 0.556
E06.5 Other chronic thyroiditis
0.000 0.444 0.555
E04.0 Non-toxic diffuse goitre
0.000 0.446 0.554
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.451 0.549
E21.0 Primary hyperparathyroidism
0.000 0.451 0.549
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.455 0.545
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.455 0.545
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.455 0.545
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.456 0.543
E26.9 Hyperaldosteronism, unspecified
0.000 0.458 0.542
E26.8 Other hyperaldosteronism
0.000 0.458 0.542
E26.1 Secondary hyperaldosteronism
0.000 0.458 0.542
E06.4 Drug-induced thyroiditis
0.000 0.459 0.541
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.459 0.541
E06.0 Acute thyroiditis
0.000 0.459 0.541
E13.3 With ophthalmic complications
0.000 0.459 0.541
E22 Hyperfunction of pituitary gland
0.000 0.463 0.537
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.466 0.534
E11.0 With coma
0.000 0.466 0.534
L40.8 Other psoriasis
0.000 0.472 0.528
E13.9 Without complications
0.000 0.473 0.527
E13.8 With unspecified complications
0.000 0.474 0.526
E13.7 With multiple complications
0.000 0.474 0.526
E13.6 With other specified complications
0.000 0.474 0.526
E13.5 With peripheral circulatory complications
0.000 0.474 0.526
E13.4 With neurological complications
0.000 0.474 0.526
E13.2 With renal complications
0.000 0.474 0.526
E13.1 With ketoacidosis
0.000 0.474 0.526
E13.0 With coma
0.000 0.474 0.526
E16.2 Hypoglycaemia, unspecified
0.000 0.475 0.525
E89.0 Postprocedural hypothyroidism
0.000 0.478 0.522
L55 Sunburn
0.000 0.482 0.518
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.513
E30.8 Other disorders of puberty
0.000 0.486 0.513
E30.1 Precocious puberty
0.000 0.486 0.513
E30.0 Delayed puberty
0.000 0.486 0.513
E31.9 Polyglandular dysfunction, unspecified
0.000 0.486 0.513
E31.8 Other polyglandular dysfunction
0.000 0.486 0.513
E31.1 Polyglandular hyperfunction
0.000 0.486 0.513
E31.0 Autoimmune polyglandular failure
0.000 0.486 0.513
E32.9 Disease of thymus, unspecified
0.000 0.486 0.513
E32.8 Other diseases of thymus
0.000 0.486 0.513
E32.1 Abscess of thymus
0.000 0.486 0.513
E32.0 Persistent hyperplasia of thymus
0.000 0.486 0.513
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.513
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.513
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E29.9 Testicular dysfunction, unspecified
0.000 0.488 0.512
E29.8 Other testicular dysfunction
0.000 0.488 0.512
E29.0 Testicular hyperfunction
0.000 0.488 0.512
E29.1 Testicular hypofunction
0.000 0.491 0.509
E06.9 Thyroiditis, unspecified
0.000 0.491 0.509
L42 Pityriasis rosea
0.000 0.493 0.507
E78.2 Mixed hyperlipidaemia
0.000 0.493 0.507
L43.3 Subacute (active) lichen planus
0.000 0.493 0.506
L43.2 Lichenoid drug reaction
0.000 0.493 0.506
L43.1 Bullous lichen planus
0.000 0.493 0.506
L43.0 Hypertrophic lichen planus
0.000 0.493 0.506
E34.5 Androgen resistance syndrome
0.000 0.502 0.498
E34.4 Constitutional tall stature
0.000 0.502 0.498
E34.3 Short stature, not elsewhere classified
0.000 0.502 0.498
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.502 0.498
E34.1 Other hypersecretion of intestinal hormones
0.000 0.502 0.498
E07 Other disorders of thyroid
0.000 0.512 0.488
E11.7 With multiple complications
0.000 0.512 0.488
E78.5 Hyperlipidaemia, unspecified
0.000 0.513 0.487
E25.9 Adrenogenital disorder, unspecified
0.000 0.516 0.484
E25.8 Other adrenogenital disorders
0.000 0.516 0.484
E88 Other metabolic disorders
0.000 0.516 0.484
E78.6 Lipoprotein deficiency
0.000 0.520 0.480
E67 Other hyperalimentation
0.000 0.521 0.479
E68 Sequelae of hyperalimentation
0.000 0.521 0.479
L58 Radiodermatitis
0.000 0.524 0.476
E11.8 With unspecified complications
0.000 0.525 0.475
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.526 0.474
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.526 0.474
E16.4 Abnormal secretion of gastrin
0.000 0.526 0.474
E16.3 Increased secretion of glucagon
0.000 0.526 0.474
M07.38 Other psoriatic arthropathies (Other)
0.000 0.533 0.466
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.533 0.466
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.533 0.466
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.533 0.466
E11.6 With other specified complications
0.000 0.534 0.466
L10-L14 Bullous disorders
0.000 0.540 0.460
E34.9 Endocrine disorder, unspecified
0.000 0.541 0.459
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.542 0.458
E16.1 Other hypoglycaemia
0.000 0.544 0.456
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.549 0.451
E45 Retarded development following protein-energy malnutrition
0.000 0.549 0.451
E43 Unspecified severe protein-energy malnutrition
0.000 0.549 0.451
E42 Marasmic kwashiorkor
0.000 0.549 0.451
E41 Nutritional marasmus
0.000 0.549 0.451
E40 Kwashiorkor
0.000 0.549 0.451
E78.1 Pure hyperglyceridaemia
0.000 0.549 0.451
E79 Disorders of purine and pyrimidine metabolism
0.000 0.550 0.449
E04.8 Other specified non-toxic goitre
0.000 0.553 0.447
E04.2 Non-toxic multinodular goitre
0.000 0.556 0.444
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.558 0.442
E89.3 Postprocedural hypopituitarism
0.000 0.564 0.436
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.564 0.436
L57.4 Cutis laxa senilis
0.000 0.571 0.429
L41.9 Parapsoriasis, unspecified
0.000 0.574 0.426
L41.8 Other parapsoriasis
0.000 0.574 0.426
L41.5 Retiform parapsoriasis
0.000 0.574 0.426
L41.4 Large plaque parapsoriasis
0.000 0.574 0.426
L41.3 Small plaque parapsoriasis
0.000 0.574 0.426
L41.2 Lymphomatoid papulosis
0.000 0.574 0.426
L41.1 Pityriasis lichenoides chronica
0.000 0.574 0.426
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.574 0.426
L44.9 Papulosquamous disorder, unspecified
0.000 0.574 0.426
L44.8 Other specified papulosquamous disorders
0.000 0.574 0.426
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.574 0.426
L44.3 Lichen ruber moniliformis
0.000 0.574 0.426
L44.2 Lichen striatus
0.000 0.574 0.426
L44.1 Lichen nitidus
0.000 0.574 0.426
L44.0 Pityriasis rubra pilaris
0.000 0.574 0.426
E84 Cystic fibrosis
0.000 0.576 0.424
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.576 0.424
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.585 0.415
E77 Disorders of glycoprotein metabolism
0.000 0.586 0.414
E76 Disorders of glycosaminoglycan metabolism
0.000 0.586 0.414
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.586 0.414
E70 Disorders of aromatic amino-acid metabolism
0.000 0.586 0.414
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.586 0.414
E06.1 Subacute thyroiditis
0.000 0.587 0.413
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.587 0.413
C44.9 Malignant neoplasm of skin, unspecified
0.001 0.590 0.410
E20.1 Pseudohypoparathyroidism
0.000 0.590 0.410
E20.0 Idiopathic hypoparathyroidism
0.000 0.590 0.410
E88.3 Tumour lysis syndrome
0.000 0.597 0.403
E04.9 Non-toxic goitre, unspecified
0.000 0.600 0.400
E88.8 Other specified metabolic disorders
0.000 0.601 0.399
E34.0 Carcinoid syndrome
0.000 0.603 0.397
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.603 0.397
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.603 0.397
E89.4 Postprocedural ovarian failure
0.000 0.604 0.396
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.605 0.395
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.606 0.394
E89.5 Postprocedural testicular hypofunction
0.000 0.606 0.394
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.608 0.392
L56.3 Solar urticaria
0.000 0.609 0.391
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.609 0.391
L56.1 Drug photoallergic response
0.000 0.609 0.391
L56.0 Drug phototoxic response
0.000 0.609 0.391
E22.1 Hyperprolactinaemia
0.000 0.613 0.387
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.615 0.385
E22.8 Other hyperfunction of pituitary gland
0.000 0.615 0.385
E89.2 Postprocedural hypoparathyroidism
0.000 0.627 0.373
L55.9 Sunburn, unspecified
0.000 0.628 0.371
L55.8 Other sunburn
0.000 0.628 0.371
L55.2 Sunburn of third degree
0.000 0.628 0.371
L55.1 Sunburn of second degree
0.000 0.628 0.371
L55.0 Sunburn of first degree
0.000 0.628 0.371
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.630 0.370
E88.2 Lipomatosis, not elsewhere classified
0.000 0.630 0.370
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.000 0.631 0.369
L59.0 Erythema ab igne [dermatitis ab igne]
0.000 0.631 0.369
E89.1 Postprocedural hypoinsulinaemia
0.000 0.632 0.368
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.000 0.634 0.366
E46 Unspecified protein-energy malnutrition
0.000 0.636 0.363
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.642 0.358
E72 Other disorders of amino-acid metabolism
0.000 0.645 0.355
L56.4 Polymorphous light eruption
0.000 0.646 0.354
E50-E64 Other nutritional deficiencies
0.000 0.649 0.351
E07.1 Dyshormogenetic goitre
0.000 0.650 0.350
E07.0 Hypersecretion of calcitonin
0.000 0.650 0.350
E20.9 Hypoparathyroidism, unspecified
0.000 0.651 0.349
E20.8 Other hypoparathyroidism
0.001 0.651 0.348
E74 Other disorders of carbohydrate metabolism
0.000 0.652 0.348
E11.1 With ketoacidosis
0.000 0.653 0.346
L12 Pemphigoid
0.000 0.655 0.345
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.655 0.345
E67.8 Other specified hyperalimentation
0.000 0.656 0.343
E67.3 Hypervitaminosis D
0.000 0.656 0.343
E67.2 Megavitamin-B6 syndrome
0.000 0.656 0.343
E67.1 Hypercarotenaemia
0.000 0.656 0.343
E67.0 Hypervitaminosis A
0.000 0.656 0.343
E11.5 With peripheral circulatory complications
0.000 0.658 0.342
L58.1 Chronic radiodermatitis
0.000 0.659 0.341
L58.0 Acute radiodermatitis
0.000 0.659 0.341
E78.4 Other hyperlipidaemia
0.000 0.662 0.338
E78.3 Hyperchylomicronaemia
0.000 0.663 0.337
E07.8 Other specified disorders of thyroid
0.000 0.664 0.336
E80.4 Gilbert's syndrome
0.000 0.668 0.332
L11 Other acantholytic disorders
0.000 0.670 0.330
L10 Pemphigus
0.000 0.670 0.330
L14 Bullous disorders in diseases classified elsewhere
0.000 0.670 0.330
E85 Amyloidosis
0.000 0.674 0.326
E88.9 Metabolic disorder, unspecified
0.000 0.675 0.325
E73 Lactose intolerance
0.000 0.676 0.324
E44.1 Mild protein-energy malnutrition
0.000 0.676 0.323
E44.0 Moderate protein-energy malnutrition
0.000 0.676 0.323
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.677 0.322
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.677 0.322
E79.1 Lesch-Nyhan syndrome
0.000 0.677 0.322
E78.8 Other disorders of lipoprotein metabolism
0.000 0.680 0.320
E84.9 Cystic fibrosis, unspecified
0.000 0.686 0.314
E80.6 Other disorders of bilirubin metabolism
0.000 0.686 0.314
E84.8 Cystic fibrosis with other manifestations
0.000 0.696 0.304
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.696 0.304
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.696 0.304
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.700 0.300
L13 Other bullous disorders
0.000 0.700 0.300
L58.9 Radiodermatitis, unspecified
0.000 0.701 0.299
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.703 0.297
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.703 0.297
E70.3 Albinism
0.000 0.703 0.297
E70.2 Disorders of tyrosine metabolism
0.000 0.703 0.297
E70.1 Other hyperphenylalaninaemias
0.000 0.703 0.297
E70.0 Classical phenylketonuria
0.000 0.703 0.297
E71.3 Disorders of fatty-acid metabolism
0.000 0.703 0.297
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.703 0.297
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.703 0.297
E71.0 Maple-syrup-urine disease
0.000 0.703 0.297
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.703 0.297
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.703 0.297
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.703 0.297
E76.2 Other mucopolysaccharidoses
0.000 0.703 0.297
E76.1 Mucopolysaccharidosis, type II
0.000 0.703 0.297
E76.0 Mucopolysaccharidosis, type I
0.000 0.703 0.297
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.703 0.297
E77.8 Other disorders of glycoprotein metabolism
0.000 0.703 0.297
E77.1 Defects in glycoprotein degradation
0.000 0.703 0.297
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.703 0.297
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.704 0.296
E80.5 Crigler-Najjar syndrome
0.000 0.704 0.296
E80.3 Defects of catalase and peroxydase
0.000 0.704 0.296
E80.0 Hereditary erythropoietic porphyria
0.000 0.704 0.296
L60-L75 Disorders of skin appendages
0.000 0.714 0.286
E75.6 Lipid storage disorder, unspecified
0.000 0.715 0.284
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.715 0.284
E75.3 Sphingolipidosis, unspecified
0.000 0.715 0.284
E75.1 Other gangliosidosis
0.000 0.715 0.284
E75.0 GM2 gangliosidosis
0.000 0.715 0.284
E03 Other hypothyroidism
0.000 0.721 0.279
E75.2 Other sphingolipidosis
0.000 0.721 0.279
E80.1 Porphyria cutanea tarda
0.000 0.721 0.278
E11.9 Without complications
0.000 0.723 0.277
E51 Thiamine deficiency
0.000 0.725 0.275
E75.5 Other lipid storage disorders
0.000 0.726 0.273
E22.0 Acromegaly and pituitary gigantism
0.000 0.729 0.271
L12.9 Pemphigoid, unspecified
0.000 0.736 0.264
E56 Other vitamin deficiencies
0.000 0.736 0.264
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.745 0.255
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.745 0.254
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.745 0.254
E72.5 Disorders of glycine metabolism
0.000 0.745 0.254
E72.4 Disorders of ornithine metabolism
0.000 0.745 0.254
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.745 0.254
E72.2 Disorders of urea cycle metabolism
0.000 0.745 0.254
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.748 0.252
E50 Vitamin A deficiency
0.000 0.748 0.252
E60 Dietary zinc deficiency
0.000 0.748 0.252
E59 Dietary selenium deficiency
0.000 0.748 0.252
E52 Niacin deficiency [pellagra]
0.000 0.748 0.252
E72.0 Disorders of amino-acid transport
0.000 0.749 0.250
E55 Vitamin D deficiency
0.000 0.750 0.250
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.750 0.250
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.750 0.250
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.750 0.250
E74.2 Disorders of galactose metabolism
0.000 0.750 0.250
E74.1 Disorders of fructose metabolism
0.000 0.750 0.250
L12.1 Cicatricial pemphigoid
0.000 0.752 0.248
L12.8 Other pemphigoid
0.000 0.752 0.248
L12.3 Acquired epidermolysis bullosa
0.000 0.752 0.248
L12.2 Chronic bullous disease of childhood
0.000 0.752 0.248
E74.0 Glycogen storage disease
0.000 0.752 0.247
L12.0 Bullous pemphigoid
0.000 0.754 0.246
E85.4 Organ-limited amyloidosis
0.000 0.757 0.243
L71 Rosacea
0.000 0.757 0.243
L11.0 Acquired keratosis follicularis
0.000 0.758 0.242
C44.5 Skin of trunk
0.000 0.758 0.242
M07 Psoriatic and enteropathic arthropathies
0.000 0.759 0.241
E63 Other nutritional deficiencies
0.000 0.760 0.240
E80.2 Other porphyria
0.000 0.762 0.238
L11.9 Acantholytic disorder, unspecified
0.000 0.763 0.237
L11.8 Other specified acantholytic disorders
0.000 0.763 0.237
L10.9 Pemphigus, unspecified
0.000 0.763 0.237
L10.8 Other pemphigus
0.000 0.763 0.237
L10.5 Drug-induced pemphigus
0.000 0.763 0.237
L10.4 Pemphigus erythematosus
0.000 0.763 0.237
L10.3 Brazilian pemphigus [fogo selvagem]
0.000 0.763 0.237
L10.2 Pemphigus foliaceus
0.000 0.763 0.237
L10.1 Pemphigus vegetans
0.000 0.763 0.237
L10.0 Pemphigus vulgaris
0.000 0.763 0.237
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.766 0.234
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.766 0.234
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.766 0.234
E73.8 Other lactose intolerance
0.000 0.767 0.232
E73.1 Secondary lactase deficiency
0.000 0.767 0.232
E73.0 Congenital lactase deficiency
0.000 0.767 0.232
L11.1 Transient acantholytic dermatosis [Grover]
0.000 0.768 0.232
E85.9 Amyloidosis, unspecified
0.000 0.770 0.230
L68 Hypertrichosis
0.000 0.771 0.229
E54 Ascorbic acid deficiency
0.000 0.773 0.227
E83 Disorders of mineral metabolism
0.067 0.773 0.161
E11.4 With neurological complications
0.000 0.777 0.223
E58 Dietary calcium deficiency
0.000 0.779 0.221
E51.2 Wernicke's encephalopathy
0.000 0.780 0.220
L50-L54 Urticaria and erythema
0.000 0.780 0.220
L66 Cicatricial alopecia [scarring hair loss]
0.000 0.781 0.219
L13.9 Bullous disorder, unspecified
0.000 0.785 0.215
L13.8 Other specified bullous disorders
0.000 0.785 0.215
L13.1 Subcorneal pustular dermatitis
0.000 0.785 0.215
L60 Nail disorders
0.000 0.788 0.211
L63 Alopecia areata
0.000 0.790 0.209
L75 Apocrine sweat disorders
0.000 0.794 0.205
L74 Eccrine sweat disorders
0.000 0.794 0.205
L67 Hair colour and hair shaft abnormalities
0.000 0.794 0.205
L64 Androgenic alopecia
0.000 0.794 0.205
L62 Nail disorders in diseases classified elsewhere
0.000 0.794 0.205
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.798 0.201
L71.9 Rosacea, unspecified
0.000 0.798 0.202
E56.1 Deficiency of vitamin K
0.000 0.798 0.201
E03.5 Myxoedema coma
0.000 0.799 0.200
E03.4 Atrophy of thyroid (acquired)
0.000 0.799 0.200
E03.3 Postinfectious hypothyroidism
0.000 0.799 0.200
L60.9 Nail disorder, unspecified
0.000 0.800 0.200
E85.8 Other amyloidosis
0.000 0.801 0.199
E51.9 Thiamine deficiency, unspecified
0.000 0.803 0.197
E51.8 Other manifestations of thiamine deficiency
0.000 0.803 0.197
E51.1 Beriberi
0.000 0.803 0.197
H00.1 Chalazion
0.197 0.803 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.804 0.196
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.806 0.193
E66 Obesity
0.000 0.806 0.194
L71.1 Rhinophyma
0.000 0.810 0.190
E56.9 Vitamin deficiency, unspecified
0.000 0.810 0.189
E56.8 Deficiency of other vitamins
0.000 0.810 0.189
E56.0 Deficiency of vitamin E
0.000 0.810 0.189
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.812 0.187
E78.0 Pure hypercholesterolaemia
0.000 0.812 0.188
L68.0 Hirsutism
0.000 0.813 0.187

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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