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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857135
log Bayes Factor = 28.9629
Chromosome 6   position 32,775,821  (GRCh37) Explore rs2857135 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E20-E35 Disorders of other endocrine glands
0.000 0.001 0.999
L40 Psoriasis
0.000 0.001 0.999
C44.7 Skin of lower limb, including hip
0.000 0.001 0.999
C44.6 Skin of upper limb, including shoulder
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
L40.9 Psoriasis, unspecified
0.000 0.004 0.996
C44.3 Skin of other and unspecified parts of face
0.000 0.004 0.996
E05.9 Thyrotoxicosis, unspecified
0.000 0.005 0.995
E23 Hypofunction and other disorders of pituitary gland
0.000 0.013 0.987
C44.4 Skin of scalp and neck
0.000 0.022 0.978
E27 Other disorders of adrenal gland
0.000 0.032 0.968
G35-G37 Demyelinating diseases of the central nervous system
0.963 0.037 0.000
G37 Other demyelinating diseases of central nervous system
0.951 0.049 0.000
L57.0 Actinic keratosis
0.000 0.053 0.947
C44.2 Skin of ear and external auricular canal
0.000 0.055 0.945
E23.7 Disorder of pituitary gland, unspecified
0.000 0.059 0.941
E10.9 Without complications
0.000 0.062 0.938
G37.9 Demyelinating disease of central nervous system, unspecified
0.929 0.071 0.000
E23.6 Other disorders of pituitary gland
0.000 0.072 0.928
J45.9 Asthma, unspecified
0.927 0.073 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.074 0.926
E10.2 With renal complications
0.000 0.081 0.919
E10.5 With peripheral circulatory complications
0.000 0.094 0.906
E10.1 With ketoacidosis
0.000 0.098 0.902
E24 Cushing's syndrome
0.000 0.105 0.895
G37.8 Other specified demyelinating diseases of central nervous system
0.872 0.128 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.156 0.844
E28 Ovarian dysfunction
0.000 0.166 0.834
J45 Asthma
0.833 0.167 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.171 0.829
L40-L45 Papulosquamous disorders
0.000 0.180 0.820
L40.1 Generalised pustular psoriasis
0.000 0.188 0.812
E11 Non-insulin-dependent diabetes mellitus
0.000 0.192 0.808
J45.0 Predominantly allergic asthma
0.808 0.192 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.201 0.799
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.202 0.798
E83.1 Disorders of iron metabolism
0.796 0.204 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.205 0.795
E23.0 Hypopituitarism
0.000 0.205 0.795
M07.3 Other psoriatic arthropathies
0.000 0.206 0.794
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.209 0.791
C44.0 Skin of lip
0.000 0.211 0.789
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.213 0.787
E10.4 With neurological complications
0.000 0.213 0.787
G36 Other acute disseminated demyelination
0.785 0.215 0.000
E11.3 With ophthalmic complications
0.000 0.217 0.783
E10.0 With coma
0.000 0.219 0.781
E06 Thyroiditis
0.000 0.222 0.778
L40.4 Guttate psoriasis
0.000 0.229 0.770
E13 Other specified diabetes mellitus
0.000 0.233 0.767
E29 Testicular dysfunction
0.000 0.243 0.757
L40.0 Psoriasis vulgaris
0.000 0.249 0.751
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.252 0.748
E26 Hyperaldosteronism
0.000 0.255 0.745
E24.0 Pituitary-dependent Cushing's disease
0.000 0.259 0.741
E24.2 Drug-induced Cushing's syndrome
0.000 0.267 0.733
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.270 0.730
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.716
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.284 0.716
E32 Diseases of thymus
0.000 0.284 0.716
E31 Polyglandular dysfunction
0.000 0.284 0.716
E30 Disorders of puberty, not elsewhere classified
0.000 0.284 0.716
L40.2 Acrodermatitis continua
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.292 0.708
E23.1 Drug-induced hypopituitarism
0.000 0.292 0.708
L43 Lichen planus
0.000 0.294 0.706
E24.9 Cushing's syndrome, unspecified
0.000 0.299 0.701
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.299 0.701
E28.2 Polycystic ovarian syndrome
0.000 0.299 0.701
E21.3 Hyperparathyroidism, unspecified
0.000 0.305 0.695
E27.5 Adrenomedullary hyperfunction
0.000 0.306 0.694
E27.0 Other adrenocortical overactivity
0.000 0.306 0.694
G37.5 Concentric sclerosis [Balo]
0.682 0.318 0.000
G37.4 Subacute necrotising myelitis
0.682 0.318 0.000
G37.2 Central pontine myelinolysis
0.682 0.318 0.000
G37.1 Central demyelination of corpus callosum
0.682 0.318 0.000
G37.0 Diffuse sclerosis
0.682 0.318 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.324 0.676
E25 Adrenogenital disorders
0.000 0.327 0.673
E06.3 Autoimmune thyroiditis
0.000 0.327 0.673
E27.9 Disorder of adrenal gland, unspecified
0.000 0.333 0.667
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.333 0.667
E11.2 With renal complications
0.000 0.334 0.666
E05.8 Other thyrotoxicosis
0.000 0.336 0.664
E65-E68 Obesity and other hyperalimentation
0.000 0.336 0.664
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.336 0.663
E10.6 With other specified complications
0.000 0.342 0.658
G36.0 Neuromyelitis optica [Devic]
0.658 0.342 0.000
E40-E46 Malnutrition
0.000 0.348 0.652
E34 Other endocrine disorders
0.000 0.350 0.650
E11.0 With coma
0.000 0.357 0.643
E24.8 Other Cushing's syndrome
0.000 0.358 0.641
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.358 0.641
E24.3 Ectopic ACTH syndrome
0.000 0.358 0.641
E24.1 Nelson's syndrome
0.000 0.358 0.641
E23.2 Diabetes insipidus
0.000 0.363 0.637
J45.8 Mixed asthma
0.636 0.364 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.369 0.631
E28.3 Primary ovarian failure
0.000 0.376 0.624
J45.1 Nonallergic asthma
0.616 0.384 0.000
E20 Hypoparathyroidism
0.000 0.388 0.612
E27.2 Addisonian crisis
0.000 0.388 0.612
E04 Other non-toxic goitre
0.000 0.391 0.609
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.391 0.609
L43.9 Lichen planus, unspecified
0.000 0.396 0.604
E27.8 Other specified disorders of adrenal gland
0.000 0.398 0.601
E28.9 Ovarian dysfunction, unspecified
0.000 0.402 0.598
E28.8 Other ovarian dysfunction
0.000 0.402 0.598
E28.1 Androgen excess
0.000 0.402 0.598
E28.0 Oestrogen excess
0.000 0.402 0.598
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.592 0.408 0.000
L44 Other papulosquamous disorders
0.000 0.412 0.588
L41 Parapsoriasis
0.000 0.412 0.588
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.412 0.588
E13.9 Without complications
0.000 0.413 0.587
E10.8 With unspecified complications
0.000 0.415 0.585
E29.1 Testicular hypofunction
0.000 0.417 0.583
E11.7 With multiple complications
0.000 0.421 0.579
E21.4 Other specified disorders of parathyroid gland
0.000 0.427 0.573
L57.5 Actinic granuloma
0.000 0.428 0.572
L57.3 Poikiloderma of Civatte
0.000 0.428 0.572
L57.2 Cutis rhomboidalis nuchae
0.000 0.428 0.572
L57.1 Actinic reticuloid
0.000 0.428 0.572
E06.5 Other chronic thyroiditis
0.000 0.429 0.571
E65 Localised adiposity
0.000 0.429 0.571
E21.2 Other hyperparathyroidism
0.000 0.431 0.569
M07.38 Other psoriatic arthropathies (Other)
0.000 0.431 0.569
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.431 0.569
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.431 0.569
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.431 0.569
E16 Other disorders of pancreatic internal secretion
0.000 0.432 0.568
E13.3 With ophthalmic complications
0.000 0.435 0.565
G36.9 Acute disseminated demyelination, unspecified
0.563 0.437 0.000
G36.8 Other specified acute disseminated demyelination
0.563 0.437 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.563 0.437 0.000
E26.0 Primary hyperaldosteronism
0.000 0.437 0.563
E11.6 With other specified complications
0.000 0.438 0.562
E11.8 With unspecified complications
0.000 0.441 0.559
E06.4 Drug-induced thyroiditis
0.000 0.442 0.558
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.442 0.558
E06.0 Acute thyroiditis
0.000 0.442 0.558
E06.9 Thyroiditis, unspecified
0.000 0.443 0.557
E22 Hyperfunction of pituitary gland
0.000 0.446 0.554
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.449 0.551
E13.8 With unspecified complications
0.000 0.450 0.550
E13.7 With multiple complications
0.000 0.450 0.550
E13.6 With other specified complications
0.000 0.450 0.550
E13.5 With peripheral circulatory complications
0.000 0.450 0.550
E13.4 With neurological complications
0.000 0.450 0.550
E13.2 With renal complications
0.000 0.450 0.550
E13.1 With ketoacidosis
0.000 0.450 0.550
E13.0 With coma
0.000 0.450 0.550
L43.8 Other lichen planus
0.000 0.452 0.548
E04.0 Non-toxic diffuse goitre
0.000 0.454 0.546
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.456 0.544
E70-E90 Metabolic disorders
0.000 0.457 0.543
E29.9 Testicular dysfunction, unspecified
0.000 0.457 0.542
E29.8 Other testicular dysfunction
0.000 0.457 0.542
E29.0 Testicular hyperfunction
0.000 0.457 0.542
E15 Nondiabetic hypoglycaemic coma
0.000 0.463 0.536
E26.9 Hyperaldosteronism, unspecified
0.000 0.466 0.534
E26.8 Other hyperaldosteronism
0.000 0.466 0.534
E26.1 Secondary hyperaldosteronism
0.000 0.466 0.534
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.473 0.527
L40.8 Other psoriasis
0.000 0.476 0.524
E34.8 Other specified endocrine disorders
0.000 0.479 0.521
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.514
E30.8 Other disorders of puberty
0.000 0.486 0.514
E30.1 Precocious puberty
0.000 0.486 0.514
E30.0 Delayed puberty
0.000 0.486 0.514
E31.9 Polyglandular dysfunction, unspecified
0.000 0.486 0.514
E31.8 Other polyglandular dysfunction
0.000 0.486 0.514
E31.1 Polyglandular hyperfunction
0.000 0.486 0.514
E31.0 Autoimmune polyglandular failure
0.000 0.486 0.514
E32.9 Disease of thymus, unspecified
0.000 0.486 0.514
E32.8 Other diseases of thymus
0.000 0.486 0.514
E32.1 Abscess of thymus
0.000 0.486 0.514
E32.0 Persistent hyperplasia of thymus
0.000 0.486 0.514
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.514
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.514
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.513
L43.3 Subacute (active) lichen planus
0.000 0.493 0.507
L43.2 Lichenoid drug reaction
0.000 0.493 0.507
L43.1 Bullous lichen planus
0.000 0.493 0.507
L43.0 Hypertrophic lichen planus
0.000 0.493 0.507
L55 Sunburn
0.000 0.497 0.503
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.501 0.499
L42 Pityriasis rosea
0.000 0.501 0.498
E89.0 Postprocedural hypothyroidism
0.000 0.516 0.484
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.517 0.483
E25.9 Adrenogenital disorder, unspecified
0.000 0.517 0.483
E25.8 Other adrenogenital disorders
0.000 0.517 0.483
E11.5 With peripheral circulatory complications
0.000 0.522 0.478
E67 Other hyperalimentation
0.000 0.524 0.476
E68 Sequelae of hyperalimentation
0.000 0.524 0.476
E78.2 Mixed hyperlipidaemia
0.000 0.527 0.473
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.532 0.468
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.533 0.467
E45 Retarded development following protein-energy malnutrition
0.000 0.533 0.467
E43 Unspecified severe protein-energy malnutrition
0.000 0.533 0.467
E42 Marasmic kwashiorkor
0.000 0.533 0.467
E41 Nutritional marasmus
0.000 0.533 0.467
E40 Kwashiorkor
0.000 0.533 0.467
E34.5 Androgen resistance syndrome
0.000 0.533 0.466
E34.4 Constitutional tall stature
0.000 0.533 0.466
E34.3 Short stature, not elsewhere classified
0.000 0.533 0.466
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.533 0.466
E34.1 Other hypersecretion of intestinal hormones
0.000 0.533 0.466
E21.0 Primary hyperparathyroidism
0.000 0.535 0.465
L58 Radiodermatitis
0.000 0.539 0.461
E78.5 Hyperlipidaemia, unspecified
0.000 0.544 0.456
E78.6 Lipoprotein deficiency
0.000 0.548 0.452
E88 Other metabolic disorders
0.000 0.551 0.449
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.557 0.443
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.559 0.441
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.560 0.440
E07 Other disorders of thyroid
0.000 0.561 0.439
E04.2 Non-toxic multinodular goitre
0.000 0.561 0.439
E20.1 Pseudohypoparathyroidism
0.000 0.561 0.439
E20.0 Idiopathic hypoparathyroidism
0.000 0.561 0.439
E04.8 Other specified non-toxic goitre
0.000 0.563 0.437
E11.1 With ketoacidosis
0.000 0.563 0.436
E06.1 Subacute thyroiditis
0.000 0.575 0.424
L10-L14 Bullous disorders
0.000 0.577 0.423
E78.1 Pure hyperglyceridaemia
0.000 0.577 0.423
E79 Disorders of purine and pyrimidine metabolism
0.000 0.577 0.423
L41.9 Parapsoriasis, unspecified
0.000 0.578 0.421
L41.8 Other parapsoriasis
0.000 0.578 0.421
L41.5 Retiform parapsoriasis
0.000 0.578 0.421
L41.4 Large plaque parapsoriasis
0.000 0.578 0.421
L41.3 Small plaque parapsoriasis
0.000 0.578 0.421
L41.2 Lymphomatoid papulosis
0.000 0.578 0.421
L41.1 Pityriasis lichenoides chronica
0.000 0.578 0.421
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.578 0.421
L44.9 Papulosquamous disorder, unspecified
0.000 0.578 0.421
L44.8 Other specified papulosquamous disorders
0.000 0.578 0.421
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.578 0.421
L44.3 Lichen ruber moniliformis
0.000 0.578 0.421
L44.2 Lichen striatus
0.000 0.578 0.421
L44.1 Lichen nitidus
0.000 0.578 0.421
L44.0 Pityriasis rubra pilaris
0.000 0.578 0.421
E34.9 Endocrine disorder, unspecified
0.000 0.581 0.418
E16.2 Hypoglycaemia, unspecified
0.000 0.582 0.418
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.585 0.415
L57.4 Cutis laxa senilis
0.000 0.587 0.413
E20.9 Hypoparathyroidism, unspecified
0.000 0.589 0.411
E89.3 Postprocedural hypopituitarism
0.000 0.590 0.410
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.592 0.408
C44.9 Malignant neoplasm of skin, unspecified
0.001 0.592 0.407
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.593 0.407
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.593 0.407
E16.4 Abnormal secretion of gastrin
0.000 0.593 0.407
E16.3 Increased secretion of glucagon
0.000 0.593 0.407
E46 Unspecified protein-energy malnutrition
0.000 0.598 0.402
E84 Cystic fibrosis
0.000 0.601 0.398
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.603 0.397
E22.8 Other hyperfunction of pituitary gland
0.000 0.603 0.397
E22.1 Hyperprolactinaemia
0.000 0.605 0.395
E11.9 Without complications
0.000 0.606 0.394
L56.3 Solar urticaria
0.000 0.610 0.390
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.610 0.390
L56.1 Drug photoallergic response
0.000 0.610 0.390
L56.0 Drug phototoxic response
0.000 0.610 0.390
E16.1 Other hypoglycaemia
0.000 0.610 0.390
E77 Disorders of glycoprotein metabolism
0.000 0.610 0.390
E76 Disorders of glycosaminoglycan metabolism
0.000 0.610 0.390
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.610 0.390
E70 Disorders of aromatic amino-acid metabolism
0.000 0.610 0.390
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.610 0.390
E88.3 Tumour lysis syndrome
0.000 0.627 0.373
E20.8 Other hypoparathyroidism
0.000 0.627 0.372
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.627 0.373
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.627 0.372
E88.8 Other specified metabolic disorders
0.000 0.631 0.369
E89.4 Postprocedural ovarian failure
0.000 0.631 0.369
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.631 0.369
E89.5 Postprocedural testicular hypofunction
0.000 0.631 0.369
E34.0 Carcinoid syndrome
0.000 0.632 0.368
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.632 0.367
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.634 0.366
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.637 0.363
E04.9 Non-toxic goitre, unspecified
0.000 0.638 0.362
L55.9 Sunburn, unspecified
0.000 0.639 0.360
L55.8 Other sunburn
0.000 0.639 0.360
L55.2 Sunburn of third degree
0.000 0.639 0.360
L55.1 Sunburn of second degree
0.000 0.639 0.360
L55.0 Sunburn of first degree
0.000 0.639 0.360
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.000 0.642 0.358
L59.0 Erythema ab igne [dermatitis ab igne]
0.000 0.642 0.358
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.000 0.646 0.353
L56.4 Polymorphous light eruption
0.000 0.648 0.352
E89.1 Postprocedural hypoinsulinaemia
0.000 0.656 0.344
E88.2 Lipomatosis, not elsewhere classified
0.000 0.658 0.342
E67.8 Other specified hyperalimentation
0.000 0.658 0.341
E67.3 Hypervitaminosis D
0.000 0.658 0.341
E67.2 Megavitamin-B6 syndrome
0.000 0.658 0.341
E67.1 Hypercarotenaemia
0.000 0.658 0.341
E67.0 Hypervitaminosis A
0.000 0.658 0.341
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.659 0.341
E50-E64 Other nutritional deficiencies
0.000 0.662 0.338
E78.4 Other hyperlipidaemia
0.000 0.663 0.337
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.664 0.336
E89.2 Postprocedural hypoparathyroidism
0.000 0.664 0.335
E44.1 Mild protein-energy malnutrition
0.000 0.665 0.335
E44.0 Moderate protein-energy malnutrition
0.000 0.665 0.335
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.666 0.334
E72 Other disorders of amino-acid metabolism
0.000 0.666 0.333
L58.1 Chronic radiodermatitis
0.000 0.669 0.331
L58.0 Acute radiodermatitis
0.000 0.669 0.331
E78.3 Hyperchylomicronaemia
0.000 0.671 0.329
E85 Amyloidosis
0.000 0.674 0.326
E74 Other disorders of carbohydrate metabolism
0.000 0.674 0.325
E73 Lactose intolerance
0.000 0.680 0.319
E07.1 Dyshormogenetic goitre
0.000 0.685 0.315
E07.0 Hypersecretion of calcitonin
0.000 0.685 0.315
E88.9 Metabolic disorder, unspecified
0.000 0.689 0.311
E78.8 Other disorders of lipoprotein metabolism
0.000 0.690 0.310
C44.5 Skin of trunk
0.000 0.695 0.305
L12 Pemphigoid
0.000 0.696 0.304
L10 Pemphigus
0.000 0.696 0.304
L14 Bullous disorders in diseases classified elsewhere
0.000 0.696 0.304
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.697 0.303
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.697 0.303
E79.1 Lesch-Nyhan syndrome
0.000 0.697 0.303
M07 Psoriatic and enteropathic arthropathies
0.000 0.699 0.301
L11 Other acantholytic disorders
0.000 0.700 0.300
E84.9 Cystic fibrosis, unspecified
0.000 0.705 0.295
L58.9 Radiodermatitis, unspecified
0.000 0.710 0.289
E84.8 Cystic fibrosis with other manifestations
0.000 0.714 0.286
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.714 0.286
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.714 0.286
E03 Other hypothyroidism
0.000 0.716 0.284
E07.8 Other specified disorders of thyroid
0.000 0.717 0.283
E22.0 Acromegaly and pituitary gigantism
0.000 0.719 0.281
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.720 0.279
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.720 0.279
E70.3 Albinism
0.000 0.720 0.279
E70.2 Disorders of tyrosine metabolism
0.000 0.720 0.279
E70.1 Other hyperphenylalaninaemias
0.000 0.720 0.279
E70.0 Classical phenylketonuria
0.000 0.720 0.279
E71.3 Disorders of fatty-acid metabolism
0.000 0.720 0.279
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.720 0.279
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.720 0.279
E71.0 Maple-syrup-urine disease
0.000 0.720 0.279
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.720 0.279
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.720 0.279
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.720 0.279
E76.2 Other mucopolysaccharidoses
0.000 0.720 0.279
E76.1 Mucopolysaccharidosis, type II
0.000 0.720 0.279
E76.0 Mucopolysaccharidosis, type I
0.000 0.720 0.279
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.720 0.279
E77.8 Other disorders of glycoprotein metabolism
0.000 0.720 0.279
E77.1 Defects in glycoprotein degradation
0.000 0.720 0.279
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.720 0.279
L13 Other bullous disorders
0.000 0.721 0.278
E80.4 Gilbert's syndrome
0.000 0.722 0.278
E80.6 Other disorders of bilirubin metabolism
0.000 0.727 0.272
E51 Thiamine deficiency
0.000 0.730 0.269
E75.6 Lipid storage disorder, unspecified
0.000 0.733 0.267
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.733 0.267
E75.3 Sphingolipidosis, unspecified
0.000 0.733 0.267
E75.1 Other gangliosidosis
0.000 0.733 0.267
E75.0 GM2 gangliosidosis
0.000 0.733 0.267
E11.4 With neurological complications
0.000 0.736 0.264
E75.2 Other sphingolipidosis
0.000 0.738 0.262
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.740 0.260
E80.5 Crigler-Najjar syndrome
0.000 0.740 0.260
E80.3 Defects of catalase and peroxydase
0.000 0.740 0.260
E80.0 Hereditary erythropoietic porphyria
0.000 0.740 0.260
L60-L75 Disorders of skin appendages
0.000 0.741 0.259
E75.5 Other lipid storage disorders
0.000 0.744 0.256
E56 Other vitamin deficiencies
0.000 0.746 0.254
E83 Disorders of mineral metabolism
0.071 0.751 0.178
E85.4 Organ-limited amyloidosis
0.000 0.753 0.247
E80.1 Porphyria cutanea tarda
0.000 0.756 0.244
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.757 0.243
E50 Vitamin A deficiency
0.000 0.757 0.243
E60 Dietary zinc deficiency
0.000 0.757 0.243
E59 Dietary selenium deficiency
0.000 0.757 0.243
E52 Niacin deficiency [pellagra]
0.000 0.757 0.243
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.761 0.239
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.761 0.239
E72.5 Disorders of glycine metabolism
0.000 0.761 0.239
E72.4 Disorders of ornithine metabolism
0.000 0.761 0.239
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.761 0.239
E72.2 Disorders of urea cycle metabolism
0.000 0.761 0.239
E72.0 Disorders of amino-acid transport
0.000 0.765 0.235
E85.9 Amyloidosis, unspecified
0.000 0.765 0.234
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.766 0.234
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.766 0.234
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.766 0.234
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.766 0.233
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.766 0.233
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.766 0.233
E74.2 Disorders of galactose metabolism
0.000 0.766 0.233
E74.1 Disorders of fructose metabolism
0.000 0.766 0.233
L12.9 Pemphigoid, unspecified
0.000 0.767 0.232
E74.0 Glycogen storage disease
0.000 0.769 0.231
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.769 0.231
E63 Other nutritional deficiencies
0.000 0.769 0.231
E73.8 Other lactose intolerance
0.000 0.771 0.229
E73.1 Secondary lactase deficiency
0.000 0.771 0.229
E73.0 Congenital lactase deficiency
0.000 0.771 0.229
E55 Vitamin D deficiency
0.000 0.771 0.229
L71 Rosacea
0.000 0.776 0.224
E51.2 Wernicke's encephalopathy
0.000 0.780 0.220
E54 Ascorbic acid deficiency
0.000 0.781 0.218
L12.8 Other pemphigoid
0.000 0.782 0.218
L12.3 Acquired epidermolysis bullosa
0.000 0.782 0.218
L12.2 Chronic bullous disease of childhood
0.000 0.782 0.218
L10.9 Pemphigus, unspecified
0.000 0.782 0.218
L10.8 Other pemphigus
0.000 0.782 0.218
L10.5 Drug-induced pemphigus
0.000 0.782 0.218
L10.4 Pemphigus erythematosus
0.000 0.782 0.218
L10.3 Brazilian pemphigus [fogo selvagem]
0.000 0.782 0.218
L10.2 Pemphigus foliaceus
0.000 0.782 0.218
L10.1 Pemphigus vegetans
0.000 0.782 0.218
L10.0 Pemphigus vulgaris
0.000 0.782 0.218
L11.0 Acquired keratosis follicularis
0.000 0.783 0.217
M07.5 Arthropathy in ulcerative colitis
0.000 0.784 0.216
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.784 0.216
M07.2 Psoriatic spondylitis
0.000 0.784 0.216
M07.1 Arthritis mutilans
0.000 0.784 0.216
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.784 0.216
L11.9 Acantholytic disorder, unspecified
0.000 0.784 0.215
L11.8 Other specified acantholytic disorders
0.000 0.784 0.215
L50-L54 Urticaria and erythema
0.000 0.788 0.212
E58 Dietary calcium deficiency
0.000 0.788 0.212
L12.1 Cicatricial pemphigoid
0.000 0.789 0.211
L11.1 Transient acantholytic dermatosis [Grover]
0.000 0.789 0.211
L12.0 Bullous pemphigoid
0.000 0.791 0.209
E80.2 Other porphyria
0.000 0.792 0.208
L68 Hypertrichosis
0.000 0.794 0.206
E78.0 Pure hypercholesterolaemia
0.000 0.795 0.205
E03.5 Myxoedema coma
0.000 0.796 0.204
E03.4 Atrophy of thyroid (acquired)
0.000 0.796 0.204
E03.3 Postinfectious hypothyroidism
0.000 0.796 0.204
C43 Malignant melanoma of skin
0.000 0.799 0.201
M07.6 Other enteropathic arthropathies
0.000 0.800 0.200
L13.9 Bullous disorder, unspecified
0.000 0.800 0.200
L13.8 Other specified bullous disorders
0.000 0.800 0.200
L13.1 Subcorneal pustular dermatitis
0.000 0.800 0.200
E03.1 Congenital hypothyroidism without goitre
0.000 0.801 0.199
E85.8 Other amyloidosis
0.000 0.801 0.198
L66 Cicatricial alopecia [scarring hair loss]
0.000 0.803 0.197
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.804 0.196
E56.1 Deficiency of vitamin K
0.000 0.806 0.193
E51.9 Thiamine deficiency, unspecified
0.000 0.806 0.193
E51.8 Other manifestations of thiamine deficiency
0.000 0.806 0.193
E51.1 Beriberi
0.000 0.806 0.193
E03.8 Other specified hypothyroidism
0.000 0.807 0.193
E85.3 Secondary systemic amyloidosis
0.000 0.807 0.193
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.808 0.192
L71.9 Rosacea, unspecified
0.000 0.808 0.192
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.810 0.189
L63 Alopecia areata
0.000 0.811 0.189
L75 Apocrine sweat disorders
0.000 0.814 0.185
L74 Eccrine sweat disorders
0.000 0.814 0.185
L67 Hair colour and hair shaft abnormalities
0.000 0.814 0.185
L64 Androgenic alopecia
0.000 0.814 0.185
L62 Nail disorders in diseases classified elsewhere
0.000 0.814 0.185

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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