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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857143
log Bayes Factor = 30.1495
Chromosome 6   position 32,772,636  (GRCh37) Explore rs2857143 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.001 0.999
C44.6 Skin of upper limb, including shoulder
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.000 0.001 0.999
E20-E35 Disorders of other endocrine glands
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.002 0.998
C44.7 Skin of lower limb, including hip
0.000 0.002 0.998
C44.3 Skin of other and unspecified parts of face
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.002 0.998
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.010 0.990
E23 Hypofunction and other disorders of pituitary gland
0.000 0.018 0.982
C44.4 Skin of scalp and neck
0.000 0.023 0.977
L57.0 Actinic keratosis
0.000 0.026 0.974
E27 Other disorders of adrenal gland
0.000 0.029 0.971
G35-G37 Demyelinating diseases of the central nervous system
0.962 0.038 0.000
G37 Other demyelinating diseases of central nervous system
0.950 0.050 0.000
C44.2 Skin of ear and external auricular canal
0.000 0.056 0.944
E23.7 Disorder of pituitary gland, unspecified
0.000 0.066 0.934
E27.1 Primary adrenocortical insufficiency
0.000 0.066 0.934
E10.9 Without complications
0.000 0.072 0.928
G37.9 Demyelinating disease of central nervous system, unspecified
0.926 0.074 0.000
E23.6 Other disorders of pituitary gland
0.000 0.079 0.921
E10.5 With peripheral circulatory complications
0.000 0.094 0.906
E10.2 With renal complications
0.000 0.095 0.905
E24 Cushing's syndrome
0.000 0.110 0.890
L40-L45 Papulosquamous disorders
0.000 0.114 0.886
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.125 0.875
G37.8 Other specified demyelinating diseases of central nervous system
0.872 0.128 0.000
J45.9 Asthma, unspecified
0.869 0.131 0.000
E10.1 With ketoacidosis
0.000 0.132 0.868
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.162 0.838
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.168 0.832
L40.1 Generalised pustular psoriasis
0.000 0.171 0.829
L40.3 Pustulosis palmaris et plantaris
0.000 0.172 0.828
E28 Ovarian dysfunction
0.000 0.178 0.822
J45 Asthma
0.812 0.188 0.000
E06 Thyroiditis
0.000 0.194 0.806
C44.0 Skin of lip
0.000 0.201 0.799
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.201 0.799
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.203 0.797
J45.0 Predominantly allergic asthma
0.796 0.204 0.000
E10.4 With neurological complications
0.000 0.204 0.796
E11 Non-insulin-dependent diabetes mellitus
0.000 0.205 0.795
M07.3 Other psoriatic arthropathies
0.000 0.210 0.790
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.212 0.788
L43 Lichen planus
0.000 0.212 0.788
G36 Other acute disseminated demyelination
0.786 0.214 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.217 0.783
E83.1 Disorders of iron metabolism
0.781 0.219 0.000
E10.0 With coma
0.000 0.222 0.778
E13 Other specified diabetes mellitus
0.000 0.230 0.770
L40.4 Guttate psoriasis
0.000 0.230 0.770
L40.0 Psoriasis vulgaris
0.000 0.230 0.770
E11.3 With ophthalmic complications
0.000 0.233 0.767
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.236 0.764
E29 Testicular dysfunction
0.000 0.240 0.760
E26 Hyperaldosteronism
0.000 0.240 0.760
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.252 0.748
E21.3 Hyperparathyroidism, unspecified
0.000 0.258 0.742
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.262 0.738
E23.0 Hypopituitarism
0.000 0.263 0.737
E24.0 Pituitary-dependent Cushing's disease
0.000 0.264 0.736
E24.2 Drug-induced Cushing's syndrome
0.000 0.272 0.728
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.275 0.725
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.716
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.284 0.716
E32 Diseases of thymus
0.000 0.284 0.716
E31 Polyglandular dysfunction
0.000 0.284 0.716
E30 Disorders of puberty, not elsewhere classified
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.285 0.715
E06.3 Autoimmune thyroiditis
0.000 0.295 0.705
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.296 0.704
E23.1 Drug-induced hypopituitarism
0.000 0.296 0.704
L43.9 Lichen planus, unspecified
0.000 0.300 0.700
E27.5 Adrenomedullary hyperfunction
0.000 0.304 0.696
E27.0 Other adrenocortical overactivity
0.000 0.304 0.696
E24.9 Cushing's syndrome, unspecified
0.000 0.307 0.693
E28.2 Polycystic ovarian syndrome
0.000 0.318 0.682
G37.5 Concentric sclerosis [Balo]
0.681 0.319 0.000
G37.4 Subacute necrotising myelitis
0.681 0.319 0.000
G37.2 Central pontine myelinolysis
0.681 0.319 0.000
G37.1 Central demyelination of corpus callosum
0.681 0.319 0.000
G37.0 Diffuse sclerosis
0.681 0.319 0.000
E11.2 With renal complications
0.000 0.323 0.677
E25 Adrenogenital disorders
0.000 0.327 0.672
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.336 0.664
E27.9 Disorder of adrenal gland, unspecified
0.000 0.336 0.664
E34 Other endocrine disorders
0.000 0.339 0.661
E05.8 Other thyrotoxicosis
0.000 0.340 0.660
G36.0 Neuromyelitis optica [Devic]
0.659 0.341 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.341 0.659
E10.6 With other specified complications
0.000 0.346 0.654
E65-E68 Obesity and other hyperalimentation
0.000 0.351 0.649
E40-E46 Malnutrition
0.000 0.353 0.647
E27.2 Addisonian crisis
0.000 0.354 0.646
E24.8 Other Cushing's syndrome
0.000 0.362 0.638
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.362 0.638
E24.3 Ectopic ACTH syndrome
0.000 0.362 0.638
E24.1 Nelson's syndrome
0.000 0.362 0.638
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.362 0.637
L44 Other papulosquamous disorders
0.000 0.365 0.635
L41 Parapsoriasis
0.000 0.365 0.635
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.365 0.635
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.369 0.630
E11.0 With coma
0.000 0.373 0.627
L57.5 Actinic granuloma
0.000 0.373 0.627
L57.3 Poikiloderma of Civatte
0.000 0.373 0.627
L57.2 Cutis rhomboidalis nuchae
0.000 0.373 0.627
L57.1 Actinic reticuloid
0.000 0.373 0.627
J45.8 Mixed asthma
0.621 0.379 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.383 0.617
E28.3 Primary ovarian failure
0.000 0.387 0.612
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.391 0.609
L43.8 Other lichen planus
0.000 0.392 0.608
J45.1 Nonallergic asthma
0.606 0.394 0.000
E23.2 Diabetes insipidus
0.000 0.396 0.604
E06.9 Thyroiditis, unspecified
0.000 0.398 0.602
E21.4 Other specified disorders of parathyroid gland
0.000 0.403 0.597
E13.9 Without complications
0.000 0.405 0.595
E16 Other disorders of pancreatic internal secretion
0.000 0.405 0.595
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.594 0.406 0.000
E11.6 With other specified complications
0.000 0.406 0.594
E20 Hypoparathyroidism
0.000 0.407 0.592
E21.2 Other hyperparathyroidism
0.000 0.408 0.592
E06.5 Other chronic thyroiditis
0.000 0.409 0.591
E29.1 Testicular hypofunction
0.000 0.410 0.590
E28.9 Ovarian dysfunction, unspecified
0.000 0.410 0.589
E28.8 Other ovarian dysfunction
0.000 0.410 0.589
E28.1 Androgen excess
0.000 0.410 0.589
E28.0 Oestrogen excess
0.000 0.410 0.589
E26.0 Primary hyperaldosteronism
0.000 0.411 0.589
E10.8 With unspecified complications
0.000 0.419 0.580
E06.4 Drug-induced thyroiditis
0.000 0.422 0.578
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.422 0.578
E06.0 Acute thyroiditis
0.000 0.422 0.578
L55 Sunburn
0.000 0.427 0.573
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.427 0.573
E11.7 With multiple complications
0.000 0.430 0.570
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.432 0.568
M07.38 Other psoriatic arthropathies (Other)
0.000 0.433 0.567
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.433 0.567
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.433 0.567
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.433 0.567
E13.3 With ophthalmic complications
0.000 0.434 0.566
E22 Hyperfunction of pituitary gland
0.000 0.435 0.565
L43.3 Subacute (active) lichen planus
0.000 0.435 0.565
L43.2 Lichenoid drug reaction
0.000 0.435 0.565
L43.1 Bullous lichen planus
0.000 0.435 0.565
L43.0 Hypertrophic lichen planus
0.000 0.435 0.565
G36.9 Acute disseminated demyelination, unspecified
0.563 0.436 0.000
G36.8 Other specified acute disseminated demyelination
0.563 0.436 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.563 0.436 0.000
E65 Localised adiposity
0.000 0.445 0.555
E13.8 With unspecified complications
0.000 0.448 0.552
E13.7 With multiple complications
0.000 0.448 0.552
E13.6 With other specified complications
0.000 0.448 0.552
E13.5 With peripheral circulatory complications
0.000 0.448 0.552
E13.4 With neurological complications
0.000 0.448 0.552
E13.2 With renal complications
0.000 0.448 0.552
E13.1 With ketoacidosis
0.000 0.448 0.552
E13.0 With coma
0.000 0.448 0.552
E15 Nondiabetic hypoglycaemic coma
0.000 0.452 0.548
E29.9 Testicular dysfunction, unspecified
0.000 0.455 0.545
E29.8 Other testicular dysfunction
0.000 0.455 0.545
E29.0 Testicular hyperfunction
0.000 0.455 0.545
E11.8 With unspecified complications
0.000 0.455 0.545
E26.9 Hyperaldosteronism, unspecified
0.000 0.455 0.545
E26.8 Other hyperaldosteronism
0.000 0.455 0.545
E26.1 Secondary hyperaldosteronism
0.000 0.455 0.545
E34.8 Other specified endocrine disorders
0.000 0.460 0.540
L42 Pityriasis rosea
0.000 0.466 0.534
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.466 0.534
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.467 0.532
L58 Radiodermatitis
0.000 0.475 0.525
L10-L14 Bullous disorders
0.000 0.477 0.523
L40.8 Other psoriasis
0.000 0.480 0.520
E04 Other non-toxic goitre
0.000 0.483 0.517
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.513
E30.8 Other disorders of puberty
0.000 0.486 0.513
E30.1 Precocious puberty
0.000 0.486 0.513
E30.0 Delayed puberty
0.000 0.486 0.513
E31.9 Polyglandular dysfunction, unspecified
0.000 0.486 0.513
E31.8 Other polyglandular dysfunction
0.000 0.486 0.513
E31.1 Polyglandular hyperfunction
0.000 0.486 0.513
E31.0 Autoimmune polyglandular failure
0.000 0.486 0.513
E32.9 Disease of thymus, unspecified
0.000 0.486 0.513
E32.8 Other diseases of thymus
0.000 0.486 0.513
E32.1 Abscess of thymus
0.000 0.486 0.513
E32.0 Persistent hyperplasia of thymus
0.000 0.486 0.513
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.513
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.513
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E21.0 Primary hyperparathyroidism
0.000 0.491 0.509
E11.5 With peripheral circulatory complications
0.000 0.506 0.494
E25.9 Adrenogenital disorder, unspecified
0.000 0.518 0.482
E25.8 Other adrenogenital disorders
0.000 0.518 0.482
E70-E90 Metabolic disorders
0.000 0.518 0.481
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.520 0.479
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.524 0.475
E34.5 Androgen resistance syndrome
0.000 0.526 0.474
E34.4 Constitutional tall stature
0.000 0.526 0.474
E34.3 Short stature, not elsewhere classified
0.000 0.526 0.474
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.526 0.474
E34.1 Other hypersecretion of intestinal hormones
0.000 0.526 0.474
E07 Other disorders of thyroid
0.000 0.528 0.471
E16.2 Hypoglycaemia, unspecified
0.000 0.531 0.469
E67 Other hyperalimentation
0.000 0.534 0.466
E68 Sequelae of hyperalimentation
0.000 0.534 0.466
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.536 0.464
E45 Retarded development following protein-energy malnutrition
0.000 0.536 0.464
E43 Unspecified severe protein-energy malnutrition
0.000 0.536 0.464
E42 Marasmic kwashiorkor
0.000 0.536 0.464
E41 Nutritional marasmus
0.000 0.536 0.464
E40 Kwashiorkor
0.000 0.536 0.464
E04.0 Non-toxic diffuse goitre
0.000 0.537 0.463
L56.3 Solar urticaria
0.000 0.543 0.457
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.543 0.457
L56.1 Drug photoallergic response
0.000 0.543 0.457
L56.0 Drug phototoxic response
0.000 0.543 0.457
L41.9 Parapsoriasis, unspecified
0.000 0.544 0.455
L41.8 Other parapsoriasis
0.000 0.544 0.455
L41.5 Retiform parapsoriasis
0.000 0.544 0.455
L41.4 Large plaque parapsoriasis
0.000 0.544 0.455
L41.3 Small plaque parapsoriasis
0.000 0.544 0.455
L41.2 Lymphomatoid papulosis
0.000 0.544 0.455
L41.1 Pityriasis lichenoides chronica
0.000 0.544 0.455
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.544 0.455
L44.9 Papulosquamous disorder, unspecified
0.000 0.544 0.455
L44.8 Other specified papulosquamous disorders
0.000 0.544 0.455
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.544 0.455
L44.3 Lichen ruber moniliformis
0.000 0.544 0.455
L44.2 Lichen striatus
0.000 0.544 0.455
L44.1 Lichen nitidus
0.000 0.544 0.455
L44.0 Pityriasis rubra pilaris
0.000 0.544 0.455
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.545 0.455
L57.4 Cutis laxa senilis
0.000 0.549 0.450
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.550 0.450
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.553 0.447
E06.1 Subacute thyroiditis
0.000 0.561 0.439
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.561 0.438
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.573 0.426
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.573 0.426
E16.4 Abnormal secretion of gastrin
0.000 0.573 0.426
E16.3 Increased secretion of glucagon
0.000 0.573 0.426
E20.1 Pseudohypoparathyroidism
0.000 0.575 0.425
E20.0 Idiopathic hypoparathyroidism
0.000 0.575 0.425
E34.9 Endocrine disorder, unspecified
0.000 0.579 0.421
E11.1 With ketoacidosis
0.000 0.579 0.420
E78.2 Mixed hyperlipidaemia
0.000 0.581 0.419
E89.0 Postprocedural hypothyroidism
0.000 0.583 0.417
L56.4 Polymorphous light eruption
0.000 0.587 0.413
L55.9 Sunburn, unspecified
0.000 0.589 0.411
L55.8 Other sunburn
0.000 0.589 0.411
L55.2 Sunburn of third degree
0.000 0.589 0.411
L55.1 Sunburn of second degree
0.000 0.589 0.411
L55.0 Sunburn of first degree
0.000 0.589 0.411
E78.5 Hyperlipidaemia, unspecified
0.000 0.593 0.407
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.000 0.593 0.407
L59.0 Erythema ab igne [dermatitis ab igne]
0.000 0.593 0.407
E16.1 Other hypoglycaemia
0.000 0.594 0.406
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.595 0.405
E22.8 Other hyperfunction of pituitary gland
0.000 0.595 0.405
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.000 0.598 0.402
E22.1 Hyperprolactinaemia
0.000 0.600 0.400
C44.9 Malignant neoplasm of skin, unspecified
0.001 0.600 0.399
E78.6 Lipoprotein deficiency
0.000 0.601 0.399
E88 Other metabolic disorders
0.000 0.602 0.398
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.605 0.395
E46 Unspecified protein-energy malnutrition
0.000 0.606 0.394
E20.9 Hypoparathyroidism, unspecified
0.000 0.618 0.382
L12 Pemphigoid
0.000 0.619 0.381
L58.1 Chronic radiodermatitis
0.000 0.623 0.377
L58.0 Acute radiodermatitis
0.000 0.623 0.377
L10 Pemphigus
0.000 0.625 0.375
L14 Bullous disorders in diseases classified elsewhere
0.000 0.625 0.375
E79 Disorders of purine and pyrimidine metabolism
0.000 0.626 0.374
E78.1 Pure hyperglyceridaemia
0.000 0.628 0.372
E34.0 Carcinoid syndrome
0.000 0.628 0.371
E04.8 Other specified non-toxic goitre
0.000 0.629 0.371
L11 Other acantholytic disorders
0.000 0.631 0.369
L13 Other bullous disorders
0.000 0.632 0.368
E20.8 Other hypoparathyroidism
0.000 0.639 0.360
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.640 0.360
C44.5 Skin of trunk
0.000 0.646 0.354
E84 Cystic fibrosis
0.000 0.647 0.352
E70 Disorders of aromatic amino-acid metabolism
0.000 0.653 0.347
E77 Disorders of glycoprotein metabolism
0.000 0.655 0.345
E76 Disorders of glycosaminoglycan metabolism
0.000 0.655 0.345
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.655 0.345
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.655 0.345
E89.3 Postprocedural hypopituitarism
0.000 0.655 0.345
L60-L75 Disorders of skin appendages
0.000 0.660 0.340
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.660 0.340
E07.1 Dyshormogenetic goitre
0.000 0.662 0.338
E07.0 Hypersecretion of calcitonin
0.000 0.662 0.338
E04.2 Non-toxic multinodular goitre
0.000 0.664 0.336
E67.8 Other specified hyperalimentation
0.000 0.666 0.334
E67.3 Hypervitaminosis D
0.000 0.666 0.334
E67.2 Megavitamin-B6 syndrome
0.000 0.666 0.334
E67.1 Hypercarotenaemia
0.000 0.666 0.334
E67.0 Hypervitaminosis A
0.000 0.666 0.334
E44.1 Mild protein-energy malnutrition
0.000 0.667 0.333
E44.0 Moderate protein-energy malnutrition
0.000 0.667 0.333
E88.3 Tumour lysis syndrome
0.000 0.669 0.331
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.670 0.330
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.671 0.329
L58.9 Radiodermatitis, unspecified
0.000 0.671 0.329
E88.8 Other specified metabolic disorders
0.000 0.673 0.327
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.679 0.320
E89.5 Postprocedural testicular hypofunction
0.000 0.679 0.320
E89.4 Postprocedural ovarian failure
0.000 0.680 0.320
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.682 0.318
E11.4 With neurological complications
0.000 0.695 0.305
E50-E64 Other nutritional deficiencies
0.000 0.696 0.304
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.696 0.303
E88.2 Lipomatosis, not elsewhere classified
0.000 0.698 0.302
E07.8 Other specified disorders of thyroid
0.000 0.698 0.301
L71 Rosacea
0.000 0.700 0.300
M07 Psoriatic and enteropathic arthropathies
0.000 0.700 0.300
E89.1 Postprocedural hypoinsulinaemia
0.000 0.701 0.298
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.703 0.297
E74 Other disorders of carbohydrate metabolism
0.000 0.704 0.296
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.705 0.295
E72 Other disorders of amino-acid metabolism
0.000 0.705 0.295
E78.4 Other hyperlipidaemia
0.000 0.706 0.294
L12.9 Pemphigoid, unspecified
0.000 0.709 0.291
E78.3 Hyperchylomicronaemia
0.000 0.709 0.290
E89.2 Postprocedural hypoparathyroidism
0.000 0.712 0.288
E78.8 Other disorders of lipoprotein metabolism
0.000 0.714 0.286
E85 Amyloidosis
0.000 0.716 0.283
E22.0 Acromegaly and pituitary gigantism
0.000 0.718 0.282
E73 Lactose intolerance
0.000 0.720 0.280
E03 Other hypothyroidism
0.000 0.721 0.279
E04.9 Non-toxic goitre, unspecified
0.000 0.723 0.277
E88.9 Metabolic disorder, unspecified
0.000 0.724 0.275
L12.8 Other pemphigoid
0.000 0.727 0.273
L12.3 Acquired epidermolysis bullosa
0.000 0.727 0.273
L12.2 Chronic bullous disease of childhood
0.000 0.727 0.273
L68 Hypertrichosis
0.000 0.730 0.270
L12.0 Bullous pemphigoid
0.000 0.731 0.269
L10.9 Pemphigus, unspecified
0.000 0.731 0.269
L10.8 Other pemphigus
0.000 0.731 0.269
L10.5 Drug-induced pemphigus
0.000 0.731 0.269
L10.4 Pemphigus erythematosus
0.000 0.731 0.269
L10.3 Brazilian pemphigus [fogo selvagem]
0.000 0.731 0.269
L10.2 Pemphigus foliaceus
0.000 0.731 0.269
L10.1 Pemphigus vegetans
0.000 0.731 0.269
L10.0 Pemphigus vulgaris
0.000 0.731 0.269
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.732 0.268
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.732 0.268
E79.1 Lesch-Nyhan syndrome
0.000 0.732 0.268
E80.4 Gilbert's syndrome
0.000 0.732 0.268
L11.0 Acquired keratosis follicularis
0.000 0.734 0.266
L11.9 Acantholytic disorder, unspecified
0.000 0.735 0.265
L11.8 Other specified acantholytic disorders
0.000 0.735 0.265
L13.9 Bullous disorder, unspecified
0.000 0.736 0.264
L13.8 Other specified bullous disorders
0.000 0.736 0.264
L13.1 Subcorneal pustular dermatitis
0.000 0.736 0.264
L12.1 Cicatricial pemphigoid
0.000 0.737 0.263
L71.9 Rosacea, unspecified
0.000 0.739 0.261
E84.9 Cystic fibrosis, unspecified
0.000 0.740 0.260
L11.1 Transient acantholytic dermatosis [Grover]
0.000 0.741 0.258
L66 Cicatricial alopecia [scarring hair loss]
0.000 0.741 0.258
L13.0 Dermatitis herpetiformis
0.000 0.743 0.257
E80.6 Other disorders of bilirubin metabolism
0.000 0.745 0.254
E84.8 Cystic fibrosis with other manifestations
0.000 0.747 0.253
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.747 0.253
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.747 0.253
E70.3 Albinism
0.000 0.749 0.251
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.751 0.249
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.751 0.249
E70.2 Disorders of tyrosine metabolism
0.000 0.751 0.249
E70.1 Other hyperphenylalaninaemias
0.000 0.751 0.249
E70.0 Classical phenylketonuria
0.000 0.751 0.249
L50-L54 Urticaria and erythema
0.000 0.751 0.249
L63 Alopecia areata
0.000 0.752 0.248
E71.3 Disorders of fatty-acid metabolism
0.000 0.752 0.248
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.752 0.248
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.752 0.248
E71.0 Maple-syrup-urine disease
0.000 0.752 0.248
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.752 0.248
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.752 0.248
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.752 0.248
E76.2 Other mucopolysaccharidoses
0.000 0.752 0.248
E76.1 Mucopolysaccharidosis, type II
0.000 0.752 0.248
E76.0 Mucopolysaccharidosis, type I
0.000 0.752 0.248
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.752 0.248
E77.8 Other disorders of glycoprotein metabolism
0.000 0.752 0.248
E77.1 Defects in glycoprotein degradation
0.000 0.752 0.248
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.752 0.248
L60 Nail disorders
0.000 0.755 0.245
L75 Apocrine sweat disorders
0.000 0.756 0.244
L74 Eccrine sweat disorders
0.000 0.756 0.244
L67 Hair colour and hair shaft abnormalities
0.000 0.756 0.244
L64 Androgenic alopecia
0.000 0.756 0.244
L62 Nail disorders in diseases classified elsewhere
0.000 0.756 0.244
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.756 0.244
E80.5 Crigler-Najjar syndrome
0.000 0.756 0.244
E80.3 Defects of catalase and peroxydase
0.000 0.756 0.244
E80.0 Hereditary erythropoietic porphyria
0.000 0.756 0.244
L71.1 Rhinophyma
0.000 0.761 0.239
E75.6 Lipid storage disorder, unspecified
0.000 0.764 0.236
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.764 0.236
E75.3 Sphingolipidosis, unspecified
0.000 0.764 0.236
E75.1 Other gangliosidosis
0.000 0.764 0.236
E75.0 GM2 gangliosidosis
0.000 0.764 0.236
E51 Thiamine deficiency
0.000 0.764 0.236
E75.2 Other sphingolipidosis
0.000 0.769 0.231
L60.9 Nail disorder, unspecified
0.000 0.770 0.230
E56 Other vitamin deficiencies
0.000 0.772 0.228
E80.1 Porphyria cutanea tarda
0.000 0.772 0.228
E75.5 Other lipid storage disorders
0.000 0.774 0.226
L65 Other nonscarring hair loss
0.000 0.777 0.222
L68.0 Hirsutism
0.000 0.779 0.221
L70 Acne
0.000 0.780 0.220
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.781 0.218
E50 Vitamin A deficiency
0.000 0.781 0.218
E60 Dietary zinc deficiency
0.000 0.781 0.218
E59 Dietary selenium deficiency
0.000 0.781 0.218
E52 Niacin deficiency [pellagra]
0.000 0.781 0.218
L71.8 Other rosacea
0.000 0.784 0.215
L71.0 Perioral dermatitis
0.000 0.784 0.215
M07.5 Arthropathy in ulcerative colitis
0.000 0.785 0.215
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.785 0.215
M07.2 Psoriatic spondylitis
0.000 0.785 0.215
M07.1 Arthritis mutilans
0.000 0.785 0.215
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.785 0.215
E85.4 Organ-limited amyloidosis
0.000 0.786 0.214
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.787 0.212
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.787 0.212
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.787 0.212
E74.2 Disorders of galactose metabolism
0.000 0.787 0.212
E74.1 Disorders of fructose metabolism
0.000 0.787 0.212
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.788 0.211
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.788 0.211
E72.5 Disorders of glycine metabolism
0.000 0.788 0.211
E72.4 Disorders of ornithine metabolism
0.000 0.788 0.211
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.788 0.211
E72.2 Disorders of urea cycle metabolism
0.000 0.788 0.211
E74.0 Glycogen storage disease
0.000 0.790 0.210
E80.2 Other porphyria
0.000 0.792 0.208
E72.0 Disorders of amino-acid transport
0.000 0.792 0.207
E63 Other nutritional deficiencies
0.000 0.792 0.207
L51 Erythema multiforme
0.000 0.796 0.204
L60.2 Onychogryphosis
0.000 0.796 0.204
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.796 0.203
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.796 0.203
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.796 0.203
E85.9 Amyloidosis, unspecified
0.000 0.797 0.203
E83 Disorders of mineral metabolism
0.087 0.799 0.114
E78.0 Pure hypercholesterolaemia
0.000 0.799 0.201
E73.8 Other lactose intolerance
0.000 0.799 0.201
E73.1 Secondary lactase deficiency
0.000 0.799 0.201
E73.0 Congenital lactase deficiency
0.000 0.799 0.201
E55 Vitamin D deficiency
0.000 0.800 0.200
L66.9 Cicatricial alopecia, unspecified
0.000 0.800 0.200
E03.5 Myxoedema coma
0.000 0.800 0.200
E03.4 Atrophy of thyroid (acquired)
0.000 0.800 0.200
E03.3 Postinfectious hypothyroidism
0.000 0.800 0.200
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.801 0.199
M07.6 Other enteropathic arthropathies
0.000 0.801 0.199
E54 Ascorbic acid deficiency
0.000 0.804 0.196
E03.1 Congenital hypothyroidism without goitre
0.000 0.805 0.194
L68.9 Hypertrichosis, unspecified
0.000 0.806 0.194
L68.8 Other hypertrichosis
0.000 0.806 0.194

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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