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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857150
log Bayes Factor = 29.8887
Chromosome 6   position 32,763,821  (GRCh37) Explore rs2857150 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E20-E35 Disorders of other endocrine glands
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
L40 Psoriasis
0.000 0.001 0.999
C44.7 Skin of lower limb, including hip
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
C44.6 Skin of upper limb, including shoulder
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
C44.3 Skin of other and unspecified parts of face
0.000 0.002 0.998
L40.9 Psoriasis, unspecified
0.000 0.003 0.997
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
E23 Hypofunction and other disorders of pituitary gland
0.000 0.012 0.988
C44.4 Skin of scalp and neck
0.000 0.019 0.981
L57.0 Actinic keratosis
0.000 0.021 0.979
E27 Other disorders of adrenal gland
0.000 0.022 0.978
G35-G37 Demyelinating diseases of the central nervous system
0.964 0.036 0.000
G37 Other demyelinating diseases of central nervous system
0.952 0.048 0.000
C44.2 Skin of ear and external auricular canal
0.000 0.051 0.949
E27.1 Primary adrenocortical insufficiency
0.000 0.056 0.944
E23.7 Disorder of pituitary gland, unspecified
0.000 0.059 0.941
E10.9 Without complications
0.000 0.061 0.939
E23.6 Other disorders of pituitary gland
0.000 0.063 0.937
J45.9 Asthma, unspecified
0.930 0.070 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.929 0.071 0.000
E10.2 With renal complications
0.000 0.082 0.918
E10.5 With peripheral circulatory complications
0.000 0.090 0.910
E10.1 With ketoacidosis
0.000 0.102 0.898
E24 Cushing's syndrome
0.000 0.107 0.893
G37.8 Other specified demyelinating diseases of central nervous system
0.873 0.127 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.132 0.868
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.150 0.850
L40-L45 Papulosquamous disorders
0.000 0.152 0.848
E28 Ovarian dysfunction
0.000 0.163 0.837
J45 Asthma
0.831 0.169 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.172 0.828
E83.1 Disorders of iron metabolism
0.825 0.175 0.000
L40.1 Generalised pustular psoriasis
0.000 0.194 0.806
J45.0 Predominantly allergic asthma
0.805 0.195 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.196 0.804
C44.0 Skin of lip
0.000 0.205 0.795
M07.3 Other psoriatic arthropathies
0.000 0.210 0.790
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.213 0.787
G36 Other acute disseminated demyelination
0.786 0.214 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.217 0.783
E10.0 With coma
0.000 0.220 0.780
E10.4 With neurological complications
0.000 0.224 0.776
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.225 0.775
E06 Thyroiditis
0.000 0.229 0.771
L40.4 Guttate psoriasis
0.000 0.230 0.770
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.230 0.770
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.233 0.767
E23.0 Hypopituitarism
0.000 0.233 0.767
E11 Non-insulin-dependent diabetes mellitus
0.000 0.234 0.766
E13 Other specified diabetes mellitus
0.000 0.238 0.762
E29 Testicular dysfunction
0.000 0.244 0.756
L40.0 Psoriasis vulgaris
0.000 0.253 0.747
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.256 0.744
E11.3 With ophthalmic complications
0.000 0.256 0.744
E24.0 Pituitary-dependent Cushing's disease
0.000 0.261 0.739
E26 Hyperaldosteronism
0.000 0.262 0.738
E24.2 Drug-induced Cushing's syndrome
0.000 0.269 0.731
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.274 0.726
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.283 0.716
E32 Diseases of thymus
0.000 0.283 0.716
E31 Polyglandular dysfunction
0.000 0.283 0.716
E30 Disorders of puberty, not elsewhere classified
0.000 0.283 0.716
E05.5 Thyroid crisis or storm
0.000 0.283 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.716
L40.2 Acrodermatitis continua
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.285 0.715
L43 Lichen planus
0.000 0.286 0.714
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.292 0.708
E23.1 Drug-induced hypopituitarism
0.000 0.292 0.708
E28.2 Polycystic ovarian syndrome
0.000 0.292 0.708
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.293 0.707
E27.5 Adrenomedullary hyperfunction
0.000 0.298 0.701
E27.0 Other adrenocortical overactivity
0.000 0.298 0.701
E24.9 Cushing's syndrome, unspecified
0.000 0.302 0.698
E27.9 Disorder of adrenal gland, unspecified
0.000 0.307 0.693
E34 Other endocrine disorders
0.000 0.314 0.685
G37.5 Concentric sclerosis [Balo]
0.682 0.318 0.000
G37.4 Subacute necrotising myelitis
0.682 0.318 0.000
G37.2 Central pontine myelinolysis
0.682 0.318 0.000
G37.1 Central demyelination of corpus callosum
0.682 0.318 0.000
G37.0 Diffuse sclerosis
0.682 0.318 0.000
E70-E90 Metabolic disorders
0.000 0.318 0.682
E25 Adrenogenital disorders
0.000 0.327 0.673
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.334 0.666
E21.3 Hyperparathyroidism, unspecified
0.000 0.335 0.665
E06.3 Autoimmune thyroiditis
0.000 0.335 0.665
E05.8 Other thyrotoxicosis
0.000 0.337 0.662
E65-E68 Obesity and other hyperalimentation
0.000 0.339 0.661
E27.2 Addisonian crisis
0.000 0.339 0.661
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.340 0.660
G36.0 Neuromyelitis optica [Devic]
0.659 0.341 0.000
E10.6 With other specified complications
0.000 0.343 0.657
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.345 0.655
E40-E46 Malnutrition
0.000 0.347 0.652
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.350 0.650
E24.8 Other Cushing's syndrome
0.000 0.360 0.640
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.360 0.640
E24.3 Ectopic ACTH syndrome
0.000 0.360 0.640
E24.1 Nelson's syndrome
0.000 0.360 0.640
J45.8 Mixed asthma
0.635 0.365 0.000
E23.2 Diabetes insipidus
0.000 0.366 0.634
E11.2 With renal complications
0.000 0.373 0.627
E27.8 Other specified disorders of adrenal gland
0.000 0.373 0.627
E28.3 Primary ovarian failure
0.000 0.375 0.625
L57.5 Actinic granuloma
0.000 0.377 0.623
L57.3 Poikiloderma of Civatte
0.000 0.377 0.623
L57.2 Cutis rhomboidalis nuchae
0.000 0.377 0.623
L57.1 Actinic reticuloid
0.000 0.377 0.623
E89.0 Postprocedural hypothyroidism
0.000 0.378 0.622
J45.1 Nonallergic asthma
0.620 0.380 0.000
E20 Hypoparathyroidism
0.000 0.390 0.610
E11.0 With coma
0.000 0.392 0.608
L44 Other papulosquamous disorders
0.000 0.392 0.608
L41 Parapsoriasis
0.000 0.392 0.608
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.392 0.608
E78.5 Hyperlipidaemia, unspecified
0.000 0.397 0.603
E78.2 Mixed hyperlipidaemia
0.000 0.399 0.601
E28.9 Ovarian dysfunction, unspecified
0.000 0.400 0.600
E28.8 Other ovarian dysfunction
0.000 0.400 0.600
E28.1 Androgen excess
0.000 0.400 0.600
E28.0 Oestrogen excess
0.000 0.400 0.600
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.401 0.599
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.596 0.403 0.000
L43.9 Lichen planus, unspecified
0.000 0.405 0.595
E10.8 With unspecified complications
0.000 0.417 0.583
E29.1 Testicular hypofunction
0.000 0.418 0.582
E04 Other non-toxic goitre
0.000 0.420 0.580
E13.9 Without complications
0.000 0.420 0.580
E78.6 Lipoprotein deficiency
0.000 0.425 0.575
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.427 0.573
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.430 0.570
E88 Other metabolic disorders
0.000 0.432 0.568
E65 Localised adiposity
0.000 0.433 0.567
M07.38 Other psoriatic arthropathies (Other)
0.000 0.433 0.566
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.433 0.566
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.433 0.566
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.433 0.566
E06.5 Other chronic thyroiditis
0.000 0.434 0.566
G36.9 Acute disseminated demyelination, unspecified
0.564 0.436 0.000
G36.8 Other specified acute disseminated demyelination
0.564 0.436 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.564 0.436 0.000
E13.3 With ophthalmic complications
0.000 0.439 0.561
E16 Other disorders of pancreatic internal secretion
0.000 0.439 0.561
E34.8 Other specified endocrine disorders
0.000 0.440 0.560
L55 Sunburn
0.000 0.444 0.556
L43.8 Other lichen planus
0.000 0.447 0.553
E06.4 Drug-induced thyroiditis
0.000 0.447 0.553
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.447 0.553
E06.0 Acute thyroiditis
0.000 0.447 0.553
E21.4 Other specified disorders of parathyroid gland
0.000 0.448 0.552
E06.9 Thyroiditis, unspecified
0.000 0.449 0.551
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.449 0.551
E26.0 Primary hyperaldosteronism
0.000 0.450 0.550
E11.7 With multiple complications
0.000 0.450 0.549
E21.2 Other hyperparathyroidism
0.000 0.452 0.548
E13.8 With unspecified complications
0.000 0.453 0.547
E13.7 With multiple complications
0.000 0.453 0.547
E13.6 With other specified complications
0.000 0.453 0.547
E13.5 With peripheral circulatory complications
0.000 0.453 0.547
E13.4 With neurological complications
0.000 0.453 0.547
E13.2 With renal complications
0.000 0.453 0.547
E13.1 With ketoacidosis
0.000 0.453 0.547
E13.0 With coma
0.000 0.453 0.547
E22 Hyperfunction of pituitary gland
0.000 0.454 0.546
E29.9 Testicular dysfunction, unspecified
0.000 0.458 0.542
E29.8 Other testicular dysfunction
0.000 0.458 0.542
E29.0 Testicular hyperfunction
0.000 0.458 0.542
E15 Nondiabetic hypoglycaemic coma
0.000 0.466 0.534
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.470 0.530
E79 Disorders of purine and pyrimidine metabolism
0.000 0.470 0.530
E11.6 With other specified complications
0.000 0.470 0.530
E26.9 Hyperaldosteronism, unspecified
0.000 0.471 0.529
E26.8 Other hyperaldosteronism
0.000 0.471 0.529
E26.1 Secondary hyperaldosteronism
0.000 0.471 0.529
E11.8 With unspecified complications
0.000 0.471 0.528
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.476 0.524
L40.8 Other psoriasis
0.000 0.477 0.522
E78.1 Pure hyperglyceridaemia
0.000 0.478 0.522
E04.0 Non-toxic diffuse goitre
0.000 0.480 0.520
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
L42 Pityriasis rosea
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.514
E30.8 Other disorders of puberty
0.000 0.486 0.514
E30.1 Precocious puberty
0.000 0.486 0.514
E30.0 Delayed puberty
0.000 0.486 0.514
E31.9 Polyglandular dysfunction, unspecified
0.000 0.486 0.514
E31.8 Other polyglandular dysfunction
0.000 0.486 0.514
E31.1 Polyglandular hyperfunction
0.000 0.486 0.514
E31.0 Autoimmune polyglandular failure
0.000 0.486 0.514
E32.9 Disease of thymus, unspecified
0.000 0.486 0.514
E32.8 Other diseases of thymus
0.000 0.486 0.514
E32.1 Abscess of thymus
0.000 0.486 0.514
E32.0 Persistent hyperplasia of thymus
0.000 0.486 0.514
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.514
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.514
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.513
L43.3 Subacute (active) lichen planus
0.000 0.488 0.512
L43.2 Lichenoid drug reaction
0.000 0.488 0.512
L43.1 Bullous lichen planus
0.000 0.488 0.512
L43.0 Hypertrophic lichen planus
0.000 0.488 0.512
L58 Radiodermatitis
0.000 0.490 0.510
E89.3 Postprocedural hypopituitarism
0.000 0.499 0.501
E84 Cystic fibrosis
0.000 0.500 0.500
E34.5 Androgen resistance syndrome
0.000 0.508 0.491
E34.4 Constitutional tall stature
0.000 0.508 0.491
E34.3 Short stature, not elsewhere classified
0.000 0.508 0.491
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.508 0.491
E34.1 Other hypersecretion of intestinal hormones
0.000 0.508 0.491
E77 Disorders of glycoprotein metabolism
0.000 0.511 0.489
E76 Disorders of glycosaminoglycan metabolism
0.000 0.511 0.489
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.511 0.489
E70 Disorders of aromatic amino-acid metabolism
0.000 0.511 0.489
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.511 0.489
L10-L14 Bullous disorders
0.000 0.511 0.489
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.515 0.485
E25.9 Adrenogenital disorder, unspecified
0.000 0.517 0.483
E25.8 Other adrenogenital disorders
0.000 0.517 0.483
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.518 0.482
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.520 0.480
E67 Other hyperalimentation
0.000 0.526 0.474
E68 Sequelae of hyperalimentation
0.000 0.526 0.474
E88.3 Tumour lysis syndrome
0.000 0.528 0.472
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.532 0.468
E45 Retarded development following protein-energy malnutrition
0.000 0.532 0.468
E43 Unspecified severe protein-energy malnutrition
0.000 0.532 0.468
E42 Marasmic kwashiorkor
0.000 0.532 0.468
E41 Nutritional marasmus
0.000 0.532 0.468
E40 Kwashiorkor
0.000 0.532 0.468
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.533 0.467
E88.8 Other specified metabolic disorders
0.000 0.533 0.467
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.534 0.466
E89.5 Postprocedural testicular hypofunction
0.000 0.534 0.466
E89.4 Postprocedural ovarian failure
0.000 0.534 0.466
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.535 0.465
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.537 0.463
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.537 0.463
E34.9 Endocrine disorder, unspecified
0.000 0.541 0.459
L57.4 Cutis laxa senilis
0.000 0.551 0.448
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.551 0.448
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.560 0.439
E20.1 Pseudohypoparathyroidism
0.000 0.563 0.437
E20.0 Idiopathic hypoparathyroidism
0.000 0.563 0.437
E07 Other disorders of thyroid
0.000 0.563 0.437
E21.0 Primary hyperparathyroidism
0.000 0.563 0.437
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.563 0.437
L41.9 Parapsoriasis, unspecified
0.000 0.564 0.436
L41.8 Other parapsoriasis
0.000 0.564 0.436
L41.5 Retiform parapsoriasis
0.000 0.564 0.436
L41.4 Large plaque parapsoriasis
0.000 0.564 0.436
L41.3 Small plaque parapsoriasis
0.000 0.564 0.436
L41.2 Lymphomatoid papulosis
0.000 0.564 0.436
L41.1 Pityriasis lichenoides chronica
0.000 0.564 0.436
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.564 0.436
L44.9 Papulosquamous disorder, unspecified
0.000 0.564 0.436
L44.8 Other specified papulosquamous disorders
0.000 0.564 0.436
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.564 0.436
L44.3 Lichen ruber moniliformis
0.000 0.564 0.436
L44.2 Lichen striatus
0.000 0.564 0.436
L44.1 Lichen nitidus
0.000 0.564 0.436
L44.0 Pityriasis rubra pilaris
0.000 0.564 0.436
E89.1 Postprocedural hypoinsulinaemia
0.000 0.565 0.434
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.566 0.433
E88.2 Lipomatosis, not elsewhere classified
0.000 0.568 0.432
L56.3 Solar urticaria
0.000 0.570 0.430
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.570 0.430
L56.1 Drug photoallergic response
0.000 0.570 0.430
L56.0 Drug phototoxic response
0.000 0.570 0.430
E11.5 With peripheral circulatory complications
0.000 0.571 0.429
E78.4 Other hyperlipidaemia
0.000 0.573 0.427
E89.2 Postprocedural hypoparathyroidism
0.000 0.577 0.422
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.579 0.421
E06.1 Subacute thyroiditis
0.000 0.579 0.420
E78.3 Hyperchylomicronaemia
0.000 0.582 0.418
E72 Other disorders of amino-acid metabolism
0.000 0.582 0.418
E04.8 Other specified non-toxic goitre
0.000 0.584 0.416
E11.1 With ketoacidosis
0.000 0.589 0.411
E16.2 Hypoglycaemia, unspecified
0.000 0.590 0.410
E20.9 Hypoparathyroidism, unspecified
0.000 0.592 0.408
E74 Other disorders of carbohydrate metabolism
0.000 0.592 0.408
E73 Lactose intolerance
0.000 0.593 0.407
E85 Amyloidosis
0.000 0.594 0.406
E04.2 Non-toxic multinodular goitre
0.000 0.594 0.406
C44.9 Malignant neoplasm of skin, unspecified
0.001 0.596 0.404
E46 Unspecified protein-energy malnutrition
0.000 0.596 0.404
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.598 0.402
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.598 0.402
E16.4 Abnormal secretion of gastrin
0.000 0.598 0.402
E16.3 Increased secretion of glucagon
0.000 0.598 0.402
L55.9 Sunburn, unspecified
0.000 0.601 0.398
L55.8 Other sunburn
0.000 0.601 0.398
L55.2 Sunburn of third degree
0.000 0.601 0.398
L55.1 Sunburn of second degree
0.000 0.601 0.398
L55.0 Sunburn of first degree
0.000 0.601 0.398
E78.8 Other disorders of lipoprotein metabolism
0.000 0.603 0.397
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.000 0.605 0.395
L59.0 Erythema ab igne [dermatitis ab igne]
0.000 0.605 0.395
E88.9 Metabolic disorder, unspecified
0.000 0.606 0.393
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.608 0.391
E22.8 Other hyperfunction of pituitary gland
0.000 0.608 0.391
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.000 0.610 0.390
E80.4 Gilbert's syndrome
0.000 0.610 0.390
E22.1 Hyperprolactinaemia
0.000 0.612 0.388
L56.4 Polymorphous light eruption
0.000 0.612 0.388
E34.0 Carcinoid syndrome
0.000 0.613 0.387
E16.1 Other hypoglycaemia
0.000 0.616 0.384
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.620 0.380
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.620 0.380
E79.1 Lesch-Nyhan syndrome
0.000 0.620 0.380
E20.8 Other hypoparathyroidism
0.000 0.629 0.371
E84.9 Cystic fibrosis, unspecified
0.000 0.630 0.369
L58.1 Chronic radiodermatitis
0.000 0.634 0.365
L58.0 Acute radiodermatitis
0.000 0.634 0.365
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.636 0.364
L12 Pemphigoid
0.000 0.636 0.364
E80.6 Other disorders of bilirubin metabolism
0.000 0.638 0.362
E84.8 Cystic fibrosis with other manifestations
0.000 0.641 0.358
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.641 0.358
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.641 0.358
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.649 0.351
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.649 0.351
E70.3 Albinism
0.000 0.649 0.351
E70.2 Disorders of tyrosine metabolism
0.000 0.649 0.351
E70.1 Other hyperphenylalaninaemias
0.000 0.649 0.351
E70.0 Classical phenylketonuria
0.000 0.649 0.351
E71.3 Disorders of fatty-acid metabolism
0.000 0.649 0.351
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.649 0.351
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.649 0.351
E71.0 Maple-syrup-urine disease
0.000 0.649 0.351
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.649 0.351
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.649 0.351
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.649 0.351
E76.2 Other mucopolysaccharidoses
0.000 0.649 0.351
E76.1 Mucopolysaccharidosis, type II
0.000 0.649 0.351
E76.0 Mucopolysaccharidosis, type I
0.000 0.649 0.351
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.649 0.351
E77.8 Other disorders of glycoprotein metabolism
0.000 0.649 0.351
E77.1 Defects in glycoprotein degradation
0.000 0.649 0.351
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.649 0.351
L10 Pemphigus
0.000 0.649 0.351
L14 Bullous disorders in diseases classified elsewhere
0.000 0.649 0.351
L11 Other acantholytic disorders
0.000 0.654 0.346
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.654 0.346
E80.5 Crigler-Najjar syndrome
0.000 0.654 0.346
E80.3 Defects of catalase and peroxydase
0.000 0.654 0.346
E80.0 Hereditary erythropoietic porphyria
0.000 0.654 0.346
L60-L75 Disorders of skin appendages
0.000 0.656 0.344
E67.8 Other specified hyperalimentation
0.000 0.660 0.340
E67.3 Hypervitaminosis D
0.000 0.660 0.340
E67.2 Megavitamin-B6 syndrome
0.000 0.660 0.340
E67.1 Hypercarotenaemia
0.000 0.660 0.340
E67.0 Hypervitaminosis A
0.000 0.660 0.340
E44.1 Mild protein-energy malnutrition
0.000 0.664 0.335
E44.0 Moderate protein-energy malnutrition
0.000 0.664 0.335
E04.9 Non-toxic goitre, unspecified
0.000 0.664 0.336
E75.6 Lipid storage disorder, unspecified
0.000 0.665 0.335
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.665 0.335
E75.3 Sphingolipidosis, unspecified
0.000 0.665 0.335
E75.1 Other gangliosidosis
0.000 0.665 0.335
E75.0 GM2 gangliosidosis
0.000 0.665 0.335
E75.2 Other sphingolipidosis
0.000 0.672 0.328
E80.1 Porphyria cutanea tarda
0.000 0.676 0.324
L13 Other bullous disorders
0.000 0.679 0.321
E75.5 Other lipid storage disorders
0.000 0.679 0.321
L58.9 Radiodermatitis, unspecified
0.000 0.680 0.319
C44.5 Skin of trunk
0.000 0.682 0.318
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.683 0.317
E50-E64 Other nutritional deficiencies
0.000 0.685 0.315
E78.0 Pure hypercholesterolaemia
0.000 0.685 0.315
E07.1 Dyshormogenetic goitre
0.000 0.686 0.313
E07.0 Hypersecretion of calcitonin
0.000 0.686 0.313
E85.4 Organ-limited amyloidosis
0.000 0.693 0.307
L71 Rosacea
0.000 0.699 0.301
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.700 0.300
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.700 0.300
E72.5 Disorders of glycine metabolism
0.000 0.700 0.300
E72.4 Disorders of ornithine metabolism
0.000 0.700 0.300
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.700 0.300
E72.2 Disorders of urea cycle metabolism
0.000 0.700 0.300
M07 Psoriatic and enteropathic arthropathies
0.000 0.700 0.299
E83 Disorders of mineral metabolism
0.078 0.702 0.220
E11.9 Without complications
0.000 0.704 0.296
E72.0 Disorders of amino-acid transport
0.000 0.705 0.294
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.707 0.292
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.707 0.292
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.707 0.292
E74.2 Disorders of galactose metabolism
0.000 0.707 0.292
E74.1 Disorders of fructose metabolism
0.000 0.707 0.292
E73.8 Other lactose intolerance
0.000 0.708 0.292
E73.1 Secondary lactase deficiency
0.000 0.708 0.292
E73.0 Congenital lactase deficiency
0.000 0.708 0.292
E85.9 Amyloidosis, unspecified
0.000 0.708 0.291
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.709 0.291
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.709 0.291
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.709 0.291
E74.0 Glycogen storage disease
0.000 0.711 0.289
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.713 0.287
E07.8 Other specified disorders of thyroid
0.000 0.719 0.280
E03 Other hypothyroidism
0.000 0.720 0.280
L12.9 Pemphigoid, unspecified
0.000 0.722 0.278
E80.2 Other porphyria
0.000 0.723 0.277
E22.0 Acromegaly and pituitary gigantism
0.000 0.725 0.275
L68 Hypertrichosis
0.000 0.726 0.274
L71.9 Rosacea, unspecified
0.000 0.737 0.263
E11.4 With neurological complications
0.000 0.738 0.262
L66 Cicatricial alopecia [scarring hair loss]
0.000 0.738 0.261
L12.8 Other pemphigoid
0.000 0.739 0.261
L12.3 Acquired epidermolysis bullosa
0.000 0.739 0.261
L12.2 Chronic bullous disease of childhood
0.000 0.739 0.261
L12.1 Cicatricial pemphigoid
0.000 0.740 0.260
L12.0 Bullous pemphigoid
0.000 0.742 0.258
L60 Nail disorders
0.000 0.744 0.256
L10.9 Pemphigus, unspecified
0.000 0.748 0.251
L10.8 Other pemphigus
0.000 0.748 0.251
L10.5 Drug-induced pemphigus
0.000 0.748 0.251
L10.4 Pemphigus erythematosus
0.000 0.748 0.251
L10.3 Brazilian pemphigus [fogo selvagem]
0.000 0.748 0.251
L10.2 Pemphigus foliaceus
0.000 0.748 0.251
L10.1 Pemphigus vegetans
0.000 0.748 0.251
L10.0 Pemphigus vulgaris
0.000 0.748 0.251
L63 Alopecia areata
0.000 0.749 0.251
L11.0 Acquired keratosis follicularis
0.000 0.750 0.250
L11.9 Acantholytic disorder, unspecified
0.000 0.751 0.248
L11.8 Other specified acantholytic disorders
0.000 0.751 0.248
E85.8 Other amyloidosis
0.000 0.753 0.247
L75 Apocrine sweat disorders
0.000 0.753 0.247
L74 Eccrine sweat disorders
0.000 0.753 0.247
L67 Hair colour and hair shaft abnormalities
0.000 0.753 0.247
L64 Androgenic alopecia
0.000 0.753 0.247
L62 Nail disorders in diseases classified elsewhere
0.000 0.753 0.247
E51 Thiamine deficiency
0.000 0.754 0.246
L50-L54 Urticaria and erythema
0.000 0.756 0.244
L11.1 Transient acantholytic dermatosis [Grover]
0.000 0.757 0.243
L60.9 Nail disorder, unspecified
0.000 0.760 0.240
E85.3 Secondary systemic amyloidosis
0.000 0.760 0.240
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.762 0.237
E56 Other vitamin deficiencies
0.000 0.764 0.236
L71.1 Rhinophyma
0.000 0.766 0.234
L13.9 Bullous disorder, unspecified
0.000 0.769 0.230
L13.8 Other specified bullous disorders
0.000 0.769 0.230
L13.1 Subcorneal pustular dermatitis
0.000 0.769 0.230
L70 Acne
0.000 0.772 0.228
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.774 0.226
E50 Vitamin A deficiency
0.000 0.774 0.226
E60 Dietary zinc deficiency
0.000 0.774 0.226
E59 Dietary selenium deficiency
0.000 0.774 0.226
E52 Niacin deficiency [pellagra]
0.000 0.774 0.226
L68.0 Hirsutism
0.000 0.777 0.223
L65 Other nonscarring hair loss
0.000 0.783 0.217
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.783 0.216
L71.8 Other rosacea
0.000 0.784 0.216
L71.0 Perioral dermatitis
0.000 0.784 0.216
M07.5 Arthropathy in ulcerative colitis
0.000 0.785 0.215
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.785 0.215
M07.2 Psoriatic spondylitis
0.000 0.785 0.215
M07.1 Arthritis mutilans
0.000 0.785 0.215
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.785 0.215
E63 Other nutritional deficiencies
0.000 0.785 0.214
E83.9 Disorder of mineral metabolism, unspecified
0.056 0.786 0.158
E83.8 Other disorders of mineral metabolism
0.056 0.786 0.158
E83.2 Disorders of zinc metabolism
0.056 0.786 0.158
E83.0 Disorders of copper metabolism
0.056 0.786 0.158
L60.2 Onychogryphosis
0.000 0.788 0.212
E55 Vitamin D deficiency
0.000 0.788 0.212
E73.9 Lactose intolerance, unspecified
0.000 0.790 0.210
E54 Ascorbic acid deficiency
0.000 0.797 0.203

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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