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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857165
log Bayes Factor = 78.1403
Chromosome 6   position 32,757,737  (GRCh37) Explore rs2857165 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M07.3 Other psoriatic arthropathies
0.000 0.000 1.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E11.3 With ophthalmic complications
0.000 0.001 0.999
K90.0 Coeliac disease
0.000 0.001 0.999
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.002 0.998
E11.9 Without complications
0.000 0.002 0.998
G35-G37 Demyelinating diseases of the central nervous system
0.998 0.002 0.000
G37 Other demyelinating diseases of central nervous system
0.997 0.003 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.003 0.997
D04 Carcinoma in situ of skin
0.000 0.003 0.997
D00-D09 In situ neoplasms
0.000 0.004 0.996
G37.9 Demyelinating disease of central nervous system, unspecified
0.995 0.005 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.005 0.995
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.005 0.995
L57.0 Actinic keratosis
0.000 0.015 0.985
D04.7 Skin of lower limb, including hip
0.000 0.023 0.977
D04.5 Skin of trunk
0.000 0.025 0.975
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.026 0.974
E10.1 With ketoacidosis
0.000 0.030 0.970
H36.0 Diabetic retinopathy
0.000 0.031 0.969
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.032 0.968
D06 Carcinoma in situ of cervix uteri
0.000 0.033 0.967
E70-E90 Metabolic disorders
0.000 0.034 0.966
C44 Other malignant neoplasms of skin
0.000 0.035 0.965
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.035 0.965
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.035 0.965
Chapter II Neoplasms
0.000 0.036 0.964
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.037 0.963
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.039 0.961
C44.7 Skin of lower limb, including hip
0.000 0.040 0.960
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.041 0.959
M06.0 Seronegative rheumatoid arthritis
0.000 0.041 0.959
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.041 0.959
C44.6 Skin of upper limb, including shoulder
0.000 0.043 0.957
E10.5 With peripheral circulatory complications
0.000 0.049 0.951
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.053 0.947
D06.9 Cervix, unspecified
0.000 0.054 0.946
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.057 0.943
L40.5 Arthropathic psoriasis
0.000 0.061 0.939
E89.0 Postprocedural hypothyroidism
0.000 0.062 0.938
C83.3 Large cell (diffuse)
0.000 0.065 0.935
E20-E35 Disorders of other endocrine glands
0.000 0.067 0.933
D04.3 Skin of other and unspecified parts of face
0.000 0.073 0.927
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.076 0.924
L40 Psoriasis
0.000 0.080 0.920
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.080 0.920
M06.3 Rheumatoid nodule
0.000 0.086 0.914
E27 Other disorders of adrenal gland
0.000 0.093 0.907
D09 Carcinoma in situ of other and unspecified sites
0.000 0.097 0.903
E10.2 With renal complications
0.000 0.099 0.901
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.102 0.898
E10.4 With neurological complications
0.000 0.103 0.897
E27.1 Primary adrenocortical insufficiency
0.000 0.105 0.895
E78.0 Pure hypercholesterolaemia
0.000 0.106 0.894
E10.0 With coma
0.000 0.111 0.889
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.884 0.116 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.117 0.883
E83.1 Disorders of iron metabolism
0.883 0.117 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.118 0.882
L40.9 Psoriasis, unspecified
0.000 0.120 0.880
G37.8 Other specified demyelinating diseases of central nervous system
0.879 0.121 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.130 0.870
L40-L45 Papulosquamous disorders
0.000 0.131 0.869
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.131 0.869
D04.4 Skin of scalp and neck
0.000 0.135 0.865
D03 Melanoma in situ
0.000 0.140 0.860
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.152 0.848
H36 Retinal disorders in diseases classified elsewhere
0.000 0.154 0.846
E10.6 With other specified complications
0.000 0.154 0.846
E23 Hypofunction and other disorders of pituitary gland
0.000 0.159 0.841
C44.3 Skin of other and unspecified parts of face
0.000 0.159 0.841
E78.6 Lipoprotein deficiency
0.000 0.161 0.839
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.167 0.833
C82.0 Small cleaved cell, follicular
0.000 0.168 0.832
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.170 0.830
E11.5 With peripheral circulatory complications
0.000 0.172 0.828
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.173 0.827
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.177 0.823
C82.2 Large cell, follicular
0.000 0.178 0.822
C91 Lymphoid leukaemia
0.000 0.180 0.820
E10.8 With unspecified complications
0.000 0.181 0.819
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.185 0.815
C43 Malignant melanoma of skin
0.000 0.186 0.814
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.189 0.811
D09.0 Bladder
0.000 0.190 0.810
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.193 0.807
E06 Thyroiditis
0.000 0.197 0.803
E89.3 Postprocedural hypopituitarism
0.000 0.199 0.801
E11.1 With ketoacidosis
0.000 0.202 0.798
D04.9 Skin, unspecified
0.000 0.204 0.796
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.213 0.787
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.214 0.786
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.220 0.780
C44.0 Skin of lip
0.000 0.222 0.778
E16 Other disorders of pancreatic internal secretion
0.000 0.224 0.776
C85.1 B-cell lymphoma, unspecified
0.000 0.226 0.774
E89.2 Postprocedural hypoparathyroidism
0.000 0.229 0.771
G36 Other acute disseminated demyelination
0.770 0.230 0.000
E89.4 Postprocedural ovarian failure
0.000 0.230 0.770
D03.5 Melanoma in situ of trunk
0.000 0.231 0.769
C44.4 Skin of scalp and neck
0.000 0.231 0.769
E78.2 Mixed hyperlipidaemia
0.000 0.233 0.767
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.234 0.766
E11.0 With coma
0.000 0.235 0.765
E78.5 Hyperlipidaemia, unspecified
0.000 0.237 0.763
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.240 0.760
E88 Other metabolic disorders
0.000 0.241 0.759
H30-H36 Disorders of choroid and retina
0.000 0.242 0.758
E13 Other specified diabetes mellitus
0.000 0.244 0.756
E79 Disorders of purine and pyrimidine metabolism
0.000 0.246 0.754
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.247 0.753
E23.7 Disorder of pituitary gland, unspecified
0.000 0.247 0.753
M06.34 Rheumatoid nodule (Hand)
0.000 0.248 0.752
D04.2 Skin of ear and external auricular canal
0.000 0.250 0.750
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.251 0.749
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.251 0.749
H35 Other retinal disorders
0.000 0.252 0.748
C83.1 Small cleaved cell (diffuse)
0.000 0.254 0.746
L40.1 Generalised pustular psoriasis
0.000 0.256 0.744
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.259 0.741
E06.3 Autoimmune thyroiditis
0.000 0.259 0.741
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.260 0.740
E78.1 Pure hyperglyceridaemia
0.000 0.260 0.740
E03.1 Congenital hypothyroidism without goitre
0.000 0.260 0.740
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.262 0.738
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.262 0.737
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.265 0.735
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.265 0.735
E23.6 Other disorders of pituitary gland
0.000 0.267 0.733
C73 Malignant neoplasm of thyroid gland
0.000 0.269 0.731
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.270 0.730
M06.8 Other specified rheumatoid arthritis
0.000 0.271 0.729
E05.8 Other thyrotoxicosis
0.000 0.271 0.729
E28 Ovarian dysfunction
0.000 0.271 0.729
H35.8 Other specified retinal disorders
0.000 0.275 0.725
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.277 0.723
E11.2 With renal complications
0.000 0.277 0.723
D09.1 Other and unspecified urinary organs
0.000 0.278 0.722
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.279 0.721
C91.9 Lymphoid leukaemia, unspecified
0.000 0.280 0.720
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.280 0.720
E70 Disorders of aromatic amino-acid metabolism
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M07.38 Other psoriatic arthropathies (Other)
0.000 0.283 0.717
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.283 0.717
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.283 0.717
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.283 0.717
M07.6 Other enteropathic arthropathies
0.000 0.283 0.717
M07.5 Arthropathy in ulcerative colitis
0.000 0.283 0.717
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.283 0.717
M07.2 Psoriatic spondylitis
0.000 0.283 0.717
M07.1 Arthritis mutilans
0.000 0.283 0.717
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.283 0.717
G37.5 Concentric sclerosis [Balo]
0.715 0.285 0.000
G37.4 Subacute necrotising myelitis
0.715 0.285 0.000
G37.2 Central pontine myelinolysis
0.715 0.285 0.000
G37.1 Central demyelination of corpus callosum
0.715 0.285 0.000
G37.0 Diffuse sclerosis
0.715 0.285 0.000
D04.8 Skin of other sites
0.000 0.285 0.714
D04.0 Skin of lip
0.000 0.285 0.714
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.286 0.714
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.286 0.714
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.286 0.714
C83.7 Burkitt's tumour
0.000 0.287 0.713
M06.4 Inflammatory polyarthropathy
0.000 0.287 0.713
H35.6 Retinal haemorrhage
0.000 0.290 0.710
E84 Cystic fibrosis
0.000 0.290 0.710
M10 Gout
0.000 0.291 0.709
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.293 0.707
D06.0 Endocervix
0.000 0.294 0.706
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.302 0.698
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.306 0.694
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.306 0.694
D06.7 Other parts of cervix
0.000 0.306 0.693
D06.1 Exocervix
0.000 0.306 0.693
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.307 0.693
E77 Disorders of glycoprotein metabolism
0.000 0.307 0.693
E76 Disorders of glycosaminoglycan metabolism
0.000 0.307 0.693
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.307 0.693
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.307 0.693
C44.8 Overlapping lesion of skin
0.000 0.308 0.692
M11 Other crystal arthropathies
0.000 0.309 0.691
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.309 0.691
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.309 0.691
C85.0 Lymphosarcoma
0.000 0.309 0.691
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.312 0.688
E89.5 Postprocedural testicular hypofunction
0.000 0.312 0.688
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.312 0.688
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.312 0.688
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.312 0.688
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.312 0.688
C82.6 Cutaneous follicle centre lymphoma
0.000 0.313 0.687
C82.5 Diffuse follicle centre lymphoma
0.000 0.313 0.687
C82.4 Follicular lymphoma grade IIIb
0.000 0.313 0.687
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.315 0.685
L42 Pityriasis rosea
0.000 0.316 0.684
D04.6 Skin of upper limb, including shoulder
0.000 0.316 0.684
C82.3 Follicular lymphoma grade IIIa
0.000 0.317 0.683
# Top node
0.000 0.318 0.682
C86 Other specified types of T/NK-cell lymphoma
0.000 0.319 0.680
D03.3 Melanoma in situ of other and unspecified parts of face
0.000 0.320 0.680
M12 Other specific arthropathies
0.000 0.322 0.678
C83.6 Undifferentiated (diffuse)
0.000 0.324 0.676
C83.5 Lymphoblastic (diffuse)
0.000 0.324 0.676
C83.4 Immunoblastic (diffuse)
0.000 0.324 0.676
C83.2 Mixed small and large cell (diffuse)
0.000 0.324 0.676
D03.2 Melanoma in situ of ear and external auricular canal
0.000 0.325 0.675
E11.8 With unspecified complications
0.000 0.327 0.673
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.327 0.673
E89.1 Postprocedural hypoinsulinaemia
0.000 0.328 0.671
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.330 0.670
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.331 0.669
E32 Diseases of thymus
0.000 0.331 0.669
E31 Polyglandular dysfunction
0.000 0.331 0.669
E30 Disorders of puberty, not elsewhere classified
0.000 0.331 0.669
D07.2 Vagina
0.000 0.332 0.668
H35.2 Other proliferative retinopathy
0.000 0.333 0.667
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.335 0.665
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.337 0.663
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.338 0.662
C91.0 Acute lymphoblastic leukaemia
0.000 0.339 0.660
L40.3 Pustulosis palmaris et plantaris
0.000 0.340 0.660
L40.2 Acrodermatitis continua
0.000 0.340 0.660
L40.4 Guttate psoriasis
0.000 0.341 0.659
D00.1 Oesophagus
0.000 0.344 0.655
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.345 0.655
M06.38 Rheumatoid nodule (Other)
0.000 0.345 0.655
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.345 0.655
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.345 0.655
M06.33 Rheumatoid nodule (Forearm)
0.000 0.345 0.655
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.345 0.655
C12 Malignant neoplasm of pyriform sinus
0.000 0.346 0.654
C94 Other leukaemias of specified cell type
0.000 0.347 0.653
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.348 0.652
E20 Hypoparathyroidism
0.000 0.348 0.652
C91.5 Adult T-cell leukaemia
0.000 0.350 0.650
E27.5 Adrenomedullary hyperfunction
0.000 0.350 0.650
E27.0 Other adrenocortical overactivity
0.000 0.350 0.650
M14 Arthropathies in other diseases classified elsewhere
0.000 0.350 0.650
D09.9 Carcinoma in situ, unspecified
0.000 0.352 0.648
D09.7 Carcinoma in situ of other specified sites
0.000 0.352 0.648
D09.3 Thyroid and other endocrine glands
0.000 0.352 0.648
D09.2 Eye
0.000 0.352 0.648
D03.4 Melanoma in situ of scalp and neck
0.000 0.353 0.647
D04.1 Skin of eyelid, including canthus
0.000 0.355 0.645
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.356 0.644
E03.8 Other specified hypothyroidism
0.000 0.356 0.644
C88 Malignant immunoproliferative diseases
0.000 0.356 0.644
E24 Cushing's syndrome
0.000 0.357 0.643
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.358 0.642
E29 Testicular dysfunction
0.000 0.362 0.638
D02.0 Larynx
0.000 0.362 0.638
C93 Monocytic leukaemia
0.000 0.363 0.637
H30 Chorioretinal inflammation
0.000 0.367 0.633
L57.5 Actinic granuloma
0.000 0.367 0.633
L57.3 Poikiloderma of Civatte
0.000 0.367 0.633
L57.2 Cutis rhomboidalis nuchae
0.000 0.367 0.633
L57.1 Actinic reticuloid
0.000 0.367 0.633
E23.2 Diabetes insipidus
0.000 0.370 0.630
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.370 0.630
D00.0 Lip, oral cavity and pharynx
0.000 0.371 0.629
D07.4 Penis
0.000 0.373 0.627
E73 Lactose intolerance
0.000 0.373 0.627
Chapter VII Diseases of the eye and adnexa
0.000 0.373 0.627
L43 Lichen planus
0.000 0.375 0.625
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.376 0.624
E15 Nondiabetic hypoglycaemic coma
0.000 0.376 0.624
L44 Other papulosquamous disorders
0.000 0.377 0.623
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.377 0.623
E26 Hyperaldosteronism
0.000 0.379 0.621
E16.1 Other hypoglycaemia
0.000 0.379 0.621
E85 Amyloidosis
0.000 0.379 0.621
D03.9 Melanoma in situ, unspecified
0.000 0.383 0.617
D03.8 Melanoma in situ of other sites
0.000 0.383 0.617
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.383 0.617
E25 Adrenogenital disorders
0.000 0.386 0.614
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.387 0.613
E88.9 Metabolic disorder, unspecified
0.000 0.388 0.612
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.388 0.611
E83 Disorders of mineral metabolism
0.034 0.391 0.575
L41 Parapsoriasis
0.000 0.392 0.608
L55 Sunburn
0.000 0.392 0.608
E88.8 Other specified metabolic disorders
0.000 0.392 0.608
E11.6 With other specified complications
0.000 0.393 0.607
G36.0 Neuromyelitis optica [Devic]
0.607 0.393 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.393 0.607
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.393 0.606
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.396 0.604
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.397 0.603
E23.1 Drug-induced hypopituitarism
0.000 0.397 0.603
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.397 0.602
E27.9 Disorder of adrenal gland, unspecified
0.000 0.400 0.600
M05.2 Rheumatoid vasculitis
0.000 0.402 0.598
D03.0 Melanoma in situ of lip
0.000 0.402 0.598
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.404 0.596
E78.8 Other disorders of lipoprotein metabolism
0.000 0.407 0.593
E14 Unspecified diabetes mellitus
0.000 0.408 0.592
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.409 0.591
E06.5 Other chronic thyroiditis
0.000 0.409 0.591
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.409 0.590
H35.0 Background retinopathy and retinal vascular changes
0.000 0.411 0.589
C44.2 Skin of ear and external auricular canal
0.000 0.411 0.589
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.412 0.588
C91.7 Other lymphoid leukaemia
0.000 0.412 0.588
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.412 0.588
C91.3 Prolymphocytic leukaemia
0.000 0.412 0.588
C91.2 Subacute lymphocytic leukaemia
0.000 0.412 0.588
D00.2 Stomach
0.000 0.415 0.585
D07.1 Vulva
0.000 0.416 0.584
C43.8 Overlapping malignant melanoma of skin
0.000 0.417 0.583
C43.0 Malignant melanoma of lip
0.000 0.417 0.583
E13.9 Without complications
0.000 0.418 0.581
E78.3 Hyperchylomicronaemia
0.000 0.419 0.581
C03 Malignant neoplasm of gum
0.000 0.419 0.581
L40.0 Psoriasis vulgaris
0.000 0.420 0.580
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.422 0.578
C91.4 Hairy-cell leukaemia
0.000 0.422 0.577
E27.8 Other specified disorders of adrenal gland
0.000 0.423 0.577
E27.2 Addisonian crisis
0.000 0.423 0.577
E06.4 Drug-induced thyroiditis
0.000 0.424 0.576
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.424 0.576
E06.0 Acute thyroiditis
0.000 0.424 0.576
E40-E46 Malnutrition
0.000 0.425 0.575
C95 Leukaemia of unspecified cell type
0.000 0.425 0.574
L58 Radiodermatitis
0.000 0.427 0.573
E28.2 Polycystic ovarian syndrome
0.000 0.427 0.573
E65-E68 Obesity and other hyperalimentation
0.000 0.428 0.572
D03.1 Melanoma in situ of eyelid, including canthus
0.000 0.429 0.570
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.430 0.570
E72 Other disorders of amino-acid metabolism
0.000 0.430 0.570
M10.0 Idiopathic gout
0.000 0.431 0.569
C43.4 Malignant melanoma of scalp and neck
0.000 0.432 0.568
D03.7 Melanoma in situ of lower limb, including hip
0.000 0.433 0.567
L57.4 Cutis laxa senilis
0.000 0.433 0.567
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.434 0.566
E07 Other disorders of thyroid
0.000 0.434 0.566
C13 Malignant neoplasm of hypopharynx
0.000 0.435 0.565
D02.4 Respiratory system, unspecified
0.000 0.435 0.564
D02.3 Other parts of respiratory system
0.000 0.435 0.564
D02.2 Bronchus and lung
0.000 0.435 0.564
D02.1 Trachea
0.000 0.435 0.564
M11.9 Crystal arthropathy, unspecified
0.000 0.436 0.564
M13 Other arthritis
0.000 0.439 0.561
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.441 0.559
E88.3 Tumour lysis syndrome
0.000 0.441 0.559
C11 Malignant neoplasm of nasopharynx
0.000 0.442 0.558
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.443 0.557
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.443 0.557
E16.4 Abnormal secretion of gastrin
0.000 0.443 0.557
E16.3 Increased secretion of glucagon
0.000 0.443 0.557
D01.0 Colon
0.000 0.446 0.554
G36.9 Acute disseminated demyelination, unspecified
0.552 0.448 0.000
G36.8 Other specified acute disseminated demyelination
0.552 0.448 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.552 0.448 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.449 0.551
C74 Malignant neoplasm of adrenal gland
0.000 0.449 0.550
C02.9 Tongue, unspecified
0.000 0.451 0.549
D01.3 Anus and anal canal
0.000 0.454 0.546
D07.6 Other and unspecified male genital organs
0.000 0.455 0.545
D07.3 Other and unspecified female genital organs
0.000 0.455 0.545
H30.9 Chorioretinal inflammation, unspecified
0.000 0.456 0.544
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.456 0.544
E13.8 With unspecified complications
0.000 0.458 0.542
E13.7 With multiple complications
0.000 0.458 0.542
E13.6 With other specified complications
0.000 0.458 0.542
E13.5 With peripheral circulatory complications
0.000 0.458 0.542
E13.4 With neurological complications
0.000 0.458 0.542
E13.3 With ophthalmic complications
0.000 0.458 0.542
E13.2 With renal complications
0.000 0.458 0.542
E13.1 With ketoacidosis
0.000 0.458 0.542
E13.0 With coma
0.000 0.458 0.542
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.459 0.541
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.459 0.541
E79.1 Lesch-Nyhan syndrome
0.000 0.459 0.541
C40-C41 Malignant neoplasms of bone and articular cartilage
0.001 0.460 0.540
E70.3 Albinism
0.000 0.461 0.539
E88.2 Lipomatosis, not elsewhere classified
0.000 0.461 0.538
C07 Malignant neoplasm of parotid gland
0.000 0.462 0.538
H35.1 Retinopathy of prematurity
0.000 0.463 0.537
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.464 0.536
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.464 0.535
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.465 0.535
E28.3 Primary ovarian failure
0.000 0.465 0.535
E16.2 Hypoglycaemia, unspecified
0.000 0.466 0.534
H53-H54 Visual disturbances and blindness
0.000 0.471 0.529
C05 Malignant neoplasm of palate
0.000 0.472 0.528
E84.9 Cystic fibrosis, unspecified
0.000 0.474 0.526
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.477 0.523
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.477 0.523
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.477 0.523
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.477 0.523
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.477 0.523
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.477 0.523
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.477 0.523
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.477 0.523
E28.9 Ovarian dysfunction, unspecified
0.000 0.477 0.522
E28.8 Other ovarian dysfunction
0.000 0.477 0.522
E28.1 Androgen excess
0.000 0.477 0.522
E28.0 Oestrogen excess
0.000 0.477 0.522
E80.1 Porphyria cutanea tarda
0.000 0.478 0.521
D03.6 Melanoma in situ of upper limb, including shoulder
0.000 0.482 0.518
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.483 0.517
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.483 0.517
D01.9 Digestive organ, unspecified
0.000 0.484 0.516
D01.7 Other specified digestive organs
0.000 0.484 0.516
D01.5 Liver, gallbladder and bile ducts
0.000 0.484 0.516
D01.4 Other and unspecified parts of intestine
0.000 0.484 0.516
D01.1 Rectosigmoid junction
0.000 0.484 0.516
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.485 0.514
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.485 0.514
E70.2 Disorders of tyrosine metabolism
0.000 0.485 0.514
E70.1 Other hyperphenylalaninaemias
0.000 0.485 0.514
E70.0 Classical phenylketonuria
0.000 0.485 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M08.9 Juvenile arthritis, unspecified
0.000 0.486 0.514
M08.8 Other juvenile arthritis
0.000 0.486 0.514
M08.4 Pauciarticular juvenile arthritis
0.000 0.486 0.514
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.486 0.514
M08.2 Juvenile arthritis with systemic onset
0.000 0.486 0.514
M08.1 Juvenile ankylosing spondylitis
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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