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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857177
log Bayes Factor = 79.6504
Chromosome 6   position 32,752,840  (GRCh37) Explore rs2857177 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M07.3 Other psoriatic arthropathies
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.001 0.999
E11.3 With ophthalmic complications
0.000 0.001 0.999
K90.0 Coeliac disease
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
D04 Carcinoma in situ of skin
0.000 0.001 0.999
D00-D09 In situ neoplasms
0.000 0.001 0.999
E11.9 Without complications
0.000 0.001 0.999
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.001 0.999
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.003 0.997
G35-G37 Demyelinating diseases of the central nervous system
0.996 0.004 0.000
G37 Other demyelinating diseases of central nervous system
0.995 0.005 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.007 0.993
C44 Other malignant neoplasms of skin
0.000 0.007 0.993
E70-E90 Metabolic disorders
0.000 0.007 0.993
G37.9 Demyelinating disease of central nervous system, unspecified
0.992 0.008 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.008 0.992
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.008 0.992
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.008 0.992
Chapter II Neoplasms
0.000 0.010 0.990
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.010 0.990
C44.7 Skin of lower limb, including hip
0.000 0.010 0.990
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.011 0.989
C44.6 Skin of upper limb, including shoulder
0.000 0.011 0.989
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.013 0.987
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.018 0.982
L57.0 Actinic keratosis
0.000 0.020 0.980
D04.5 Skin of trunk
0.000 0.023 0.977
D04.7 Skin of lower limb, including hip
0.000 0.024 0.976
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.024 0.976
E78.0 Pure hypercholesterolaemia
0.000 0.025 0.975
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.028 0.972
H36.0 Diabetic retinopathy
0.000 0.032 0.968
D06 Carcinoma in situ of cervix uteri
0.000 0.032 0.968
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.034 0.966
C83.3 Large cell (diffuse)
0.000 0.035 0.965
E10.1 With ketoacidosis
0.000 0.037 0.963
L40.5 Arthropathic psoriasis
0.000 0.043 0.957
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.045 0.955
E89.0 Postprocedural hypothyroidism
0.000 0.046 0.954
E10.5 With peripheral circulatory complications
0.000 0.051 0.949
D06.9 Cervix, unspecified
0.000 0.055 0.945
M06.0 Seronegative rheumatoid arthritis
0.000 0.064 0.936
C44.3 Skin of other and unspecified parts of face
0.000 0.066 0.934
L40 Psoriasis
0.000 0.066 0.934
D09 Carcinoma in situ of other and unspecified sites
0.000 0.074 0.926
D04.3 Skin of other and unspecified parts of face
0.000 0.080 0.920
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.083 0.917
M06.3 Rheumatoid nodule
0.000 0.085 0.915
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.089 0.911
E83.1 Disorders of iron metabolism
0.910 0.089 0.000
L40.9 Psoriasis, unspecified
0.000 0.092 0.908
E20-E35 Disorders of other endocrine glands
0.000 0.096 0.904
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.106 0.894
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.110 0.890
E10.4 With neurological complications
0.000 0.110 0.890
E78.6 Lipoprotein deficiency
0.000 0.111 0.889
E10.0 With coma
0.000 0.112 0.888
E10.2 With renal complications
0.000 0.121 0.879
G37.8 Other specified demyelinating diseases of central nervous system
0.878 0.122 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.124 0.876
D04.4 Skin of scalp and neck
0.000 0.126 0.874
E27 Other disorders of adrenal gland
0.000 0.132 0.868
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.132 0.868
C91 Lymphoid leukaemia
0.000 0.134 0.866
E06 Thyroiditis
0.000 0.144 0.856
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.855 0.145 0.000
D09.0 Bladder
0.000 0.147 0.853
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.148 0.852
E27.1 Primary adrenocortical insufficiency
0.000 0.148 0.852
E11.5 With peripheral circulatory complications
0.000 0.149 0.851
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.149 0.851
D03 Melanoma in situ
0.000 0.150 0.850
C82.0 Small cleaved cell, follicular
0.000 0.154 0.846
E88 Other metabolic disorders
0.000 0.158 0.842
C85.1 B-cell lymphoma, unspecified
0.000 0.158 0.842
C82.2 Large cell, follicular
0.000 0.164 0.836
E78.5 Hyperlipidaemia, unspecified
0.000 0.166 0.834
E10.8 With unspecified complications
0.000 0.166 0.834
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.168 0.832
L40-L45 Papulosquamous disorders
0.000 0.168 0.832
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.171 0.829
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.173 0.827
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.175 0.825
D04.9 Skin, unspecified
0.000 0.179 0.821
E16 Other disorders of pancreatic internal secretion
0.000 0.182 0.818
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.183 0.817
E78.2 Mixed hyperlipidaemia
0.000 0.187 0.813
E23 Hypofunction and other disorders of pituitary gland
0.000 0.188 0.812
C44.4 Skin of scalp and neck
0.000 0.195 0.805
E06.3 Autoimmune thyroiditis
0.000 0.196 0.804
E10.6 With other specified complications
0.000 0.200 0.800
E11.1 With ketoacidosis
0.000 0.206 0.794
C43 Malignant melanoma of skin
0.000 0.207 0.793
E89.3 Postprocedural hypopituitarism
0.000 0.210 0.790
E89.4 Postprocedural ovarian failure
0.000 0.213 0.787
E89.2 Postprocedural hypoparathyroidism
0.000 0.213 0.787
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.215 0.785
C73 Malignant neoplasm of thyroid gland
0.000 0.216 0.784
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.217 0.783
E11.0 With coma
0.000 0.219 0.781
E79 Disorders of purine and pyrimidine metabolism
0.000 0.225 0.775
E78.1 Pure hyperglyceridaemia
0.000 0.229 0.771
G36 Other acute disseminated demyelination
0.769 0.231 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.233 0.767
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.235 0.765
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.236 0.764
C83.1 Small cleaved cell (diffuse)
0.000 0.239 0.761
C91.9 Lymphoid leukaemia, unspecified
0.000 0.240 0.760
C83.7 Burkitt's tumour
0.000 0.241 0.759
C44.0 Skin of lip
0.000 0.241 0.759
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.241 0.759
M06.34 Rheumatoid nodule (Hand)
0.000 0.243 0.757
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.244 0.756
L40.1 Generalised pustular psoriasis
0.000 0.246 0.754
E13 Other specified diabetes mellitus
0.000 0.248 0.752
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.248 0.751
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.249 0.751
D04.2 Skin of ear and external auricular canal
0.000 0.250 0.750
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.251 0.749
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.251 0.749
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.253 0.747
M06.4 Inflammatory polyarthropathy
0.000 0.253 0.747
D03.5 Melanoma in situ of trunk
0.000 0.253 0.747
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.260 0.740
D09.1 Other and unspecified urinary organs
0.000 0.261 0.739
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.262 0.737
E70 Disorders of aromatic amino-acid metabolism
0.000 0.263 0.737
E28 Ovarian dysfunction
0.000 0.271 0.729
E84 Cystic fibrosis
0.000 0.271 0.729
M06.8 Other specified rheumatoid arthritis
0.000 0.272 0.728
E05.8 Other thyrotoxicosis
0.000 0.272 0.728
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.273 0.727
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.274 0.726
E23.7 Disorder of pituitary gland, unspecified
0.000 0.274 0.726
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.275 0.725
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.276 0.724
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.277 0.723
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.279 0.721
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M07.38 Other psoriatic arthropathies (Other)
0.000 0.283 0.717
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.283 0.717
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.283 0.717
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M07.6 Other enteropathic arthropathies
0.000 0.283 0.717
M07.5 Arthropathy in ulcerative colitis
0.000 0.283 0.717
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.283 0.717
M07.2 Psoriatic spondylitis
0.000 0.283 0.717
M07.1 Arthritis mutilans
0.000 0.283 0.717
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.283 0.717
D04.8 Skin of other sites
0.000 0.284 0.716
D04.0 Skin of lip
0.000 0.284 0.716
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.285 0.715
G37.5 Concentric sclerosis [Balo]
0.714 0.286 0.000
G37.4 Subacute necrotising myelitis
0.714 0.286 0.000
G37.2 Central pontine myelinolysis
0.714 0.286 0.000
G37.1 Central demyelination of corpus callosum
0.714 0.286 0.000
G37.0 Diffuse sclerosis
0.714 0.286 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.286 0.714
M10 Gout
0.000 0.288 0.712
C44.8 Overlapping lesion of skin
0.000 0.288 0.712
E77 Disorders of glycoprotein metabolism
0.000 0.288 0.712
E76 Disorders of glycosaminoglycan metabolism
0.000 0.288 0.712
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.288 0.712
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.288 0.712
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.288 0.712
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.288 0.711
E88.8 Other specified metabolic disorders
0.000 0.288 0.711
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.289 0.711
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.291 0.709
C85.0 Lymphosarcoma
0.000 0.291 0.709
E11.2 With renal complications
0.000 0.291 0.709
D04.6 Skin of upper limb, including shoulder
0.000 0.292 0.708
E23.6 Other disorders of pituitary gland
0.000 0.293 0.707
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.294 0.706
D06.0 Endocervix
0.000 0.294 0.705
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.294 0.705
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.296 0.704
E89.5 Postprocedural testicular hypofunction
0.000 0.296 0.704
E03.1 Congenital hypothyroidism without goitre
0.000 0.298 0.702
C91.5 Adult T-cell leukaemia
0.000 0.298 0.702
H36 Retinal disorders in diseases classified elsewhere
0.000 0.299 0.701
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.299 0.701
C82.6 Cutaneous follicle centre lymphoma
0.000 0.300 0.699
C82.5 Diffuse follicle centre lymphoma
0.000 0.300 0.699
C82.4 Follicular lymphoma grade IIIb
0.000 0.300 0.699
C88 Malignant immunoproliferative diseases
0.000 0.302 0.698
C83.6 Undifferentiated (diffuse)
0.000 0.303 0.697
C83.5 Lymphoblastic (diffuse)
0.000 0.303 0.697
C83.4 Immunoblastic (diffuse)
0.000 0.303 0.697
C83.2 Mixed small and large cell (diffuse)
0.000 0.303 0.697
C91.0 Acute lymphoblastic leukaemia
0.000 0.304 0.696
D06.7 Other parts of cervix
0.000 0.306 0.694
D06.1 Exocervix
0.000 0.306 0.694
C86 Other specified types of T/NK-cell lymphoma
0.000 0.308 0.692
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.310 0.690
E89.1 Postprocedural hypoinsulinaemia
0.000 0.313 0.687
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.316 0.684
E88.9 Metabolic disorder, unspecified
0.000 0.322 0.678
M12 Other specific arthropathies
0.000 0.323 0.676
M11 Other crystal arthropathies
0.000 0.325 0.675
E16.1 Other hypoglycaemia
0.000 0.327 0.673
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.328 0.672
E11.8 With unspecified complications
0.000 0.329 0.671
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.329 0.671
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.329 0.671
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.329 0.671
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.329 0.671
C94 Other leukaemias of specified cell type
0.000 0.330 0.670
L40.3 Pustulosis palmaris et plantaris
0.000 0.330 0.669
L40.2 Acrodermatitis continua
0.000 0.330 0.669
L40.4 Guttate psoriasis
0.000 0.332 0.668
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.333 0.667
C12 Malignant neoplasm of pyriform sinus
0.000 0.334 0.666
D03.2 Melanoma in situ of ear and external auricular canal
0.000 0.334 0.666
D09.9 Carcinoma in situ, unspecified
0.000 0.336 0.664
D09.7 Carcinoma in situ of other specified sites
0.000 0.336 0.664
D09.3 Thyroid and other endocrine glands
0.000 0.336 0.664
D09.2 Eye
0.000 0.336 0.664
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.338 0.662
E06.5 Other chronic thyroiditis
0.000 0.342 0.658
C82.3 Follicular lymphoma grade IIIa
0.000 0.342 0.658
D00.1 Oesophagus
0.000 0.344 0.656
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.344 0.656
M06.38 Rheumatoid nodule (Other)
0.000 0.344 0.656
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.344 0.656
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.344 0.656
M06.33 Rheumatoid nodule (Forearm)
0.000 0.344 0.656
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.344 0.656
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.346 0.654
L42 Pityriasis rosea
0.000 0.347 0.653
C93 Monocytic leukaemia
0.000 0.347 0.653
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.347 0.652
D03.3 Melanoma in situ of other and unspecified parts of face
0.000 0.349 0.651
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.352 0.648
E32 Diseases of thymus
0.000 0.352 0.648
E31 Polyglandular dysfunction
0.000 0.352 0.648
E30 Disorders of puberty, not elsewhere classified
0.000 0.352 0.648
E29 Testicular dysfunction
0.000 0.352 0.648
D04.1 Skin of eyelid, including canthus
0.000 0.354 0.646
E15 Nondiabetic hypoglycaemic coma
0.000 0.359 0.641
E03.8 Other specified hypothyroidism
0.000 0.359 0.641
D07.2 Vagina
0.000 0.360 0.640
E73 Lactose intolerance
0.000 0.362 0.638
M05.2 Rheumatoid vasculitis
0.000 0.364 0.636
E85 Amyloidosis
0.000 0.367 0.633
E11.6 With other specified complications
0.000 0.367 0.632
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.368 0.632
D03.4 Melanoma in situ of scalp and neck
0.000 0.368 0.632
C91.4 Hairy-cell leukaemia
0.000 0.368 0.632
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.370 0.630
L43 Lichen planus
0.000 0.371 0.629
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.371 0.629
D00.0 Lip, oral cavity and pharynx
0.000 0.371 0.629
D02.0 Larynx
0.000 0.371 0.629
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.372 0.628
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.373 0.627
E20 Hypoparathyroidism
0.000 0.376 0.624
E27.5 Adrenomedullary hyperfunction
0.000 0.377 0.623
E27.0 Other adrenocortical overactivity
0.000 0.377 0.623
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.377 0.622
M14 Arthropathies in other diseases classified elsewhere
0.000 0.379 0.621
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.379 0.621
C91.7 Other lymphoid leukaemia
0.000 0.379 0.621
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.379 0.621
C91.3 Prolymphocytic leukaemia
0.000 0.379 0.621
C91.2 Subacute lymphocytic leukaemia
0.000 0.379 0.621
E88.3 Tumour lysis syndrome
0.000 0.381 0.619
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.381 0.619
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.382 0.618
E78.8 Other disorders of lipoprotein metabolism
0.000 0.384 0.616
E24 Cushing's syndrome
0.000 0.386 0.614
E06.4 Drug-induced thyroiditis
0.000 0.386 0.614
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.386 0.614
E06.0 Acute thyroiditis
0.000 0.386 0.614
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.388 0.612
D07.4 Penis
0.000 0.390 0.610
D03.9 Melanoma in situ, unspecified
0.000 0.391 0.609
D03.8 Melanoma in situ of other sites
0.000 0.391 0.609
C95 Leukaemia of unspecified cell type
0.000 0.392 0.608
E78.3 Hyperchylomicronaemia
0.000 0.393 0.607
G36.0 Neuromyelitis optica [Devic]
0.606 0.394 0.000
E14 Unspecified diabetes mellitus
0.000 0.396 0.604
L40.0 Psoriasis vulgaris
0.000 0.398 0.602
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.398 0.602
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.399 0.601
E23.2 Diabetes insipidus
0.000 0.400 0.600
E26 Hyperaldosteronism
0.000 0.400 0.600
E16.2 Hypoglycaemia, unspecified
0.000 0.402 0.598
D03.7 Melanoma in situ of lower limb, including hip
0.000 0.403 0.597
L44 Other papulosquamous disorders
0.000 0.404 0.596
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.404 0.596
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.404 0.596
E88.2 Lipomatosis, not elsewhere classified
0.000 0.404 0.596
E65-E68 Obesity and other hyperalimentation
0.000 0.404 0.595
E25 Adrenogenital disorders
0.000 0.405 0.595
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.405 0.594
L57.5 Actinic granuloma
0.000 0.407 0.593
L57.3 Poikiloderma of Civatte
0.000 0.407 0.593
L57.2 Cutis rhomboidalis nuchae
0.000 0.407 0.593
L57.1 Actinic reticuloid
0.000 0.407 0.593
C03 Malignant neoplasm of gum
0.000 0.407 0.593
D03.0 Melanoma in situ of lip
0.000 0.410 0.590
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.413 0.587
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.413 0.587
E16.4 Abnormal secretion of gastrin
0.000 0.413 0.587
E16.3 Increased secretion of glucagon
0.000 0.413 0.587
E28.2 Polycystic ovarian syndrome
0.000 0.414 0.586
D00.2 Stomach
0.000 0.414 0.586
E72 Other disorders of amino-acid metabolism
0.000 0.415 0.585
E83 Disorders of mineral metabolism
0.044 0.416 0.540
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.417 0.583
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.418 0.582
E23.1 Drug-induced hypopituitarism
0.000 0.418 0.582
C71 Malignant neoplasm of brain
0.000 0.418 0.582
L41 Parapsoriasis
0.000 0.418 0.582
D01.0 Colon
0.000 0.419 0.581
C74 Malignant neoplasm of adrenal gland
0.000 0.420 0.580
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.423 0.577
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.424 0.576
C13 Malignant neoplasm of hypopharynx
0.000 0.424 0.576
M13 Other arthritis
0.000 0.425 0.575
E13.9 Without complications
0.000 0.426 0.574
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.427 0.573
E27.9 Disorder of adrenal gland, unspecified
0.000 0.428 0.572
M10.0 Idiopathic gout
0.000 0.430 0.570
E27.8 Other specified disorders of adrenal gland
0.000 0.430 0.569
C43.8 Overlapping malignant melanoma of skin
0.000 0.431 0.569
C43.0 Malignant melanoma of lip
0.000 0.431 0.569
C11 Malignant neoplasm of nasopharynx
0.000 0.431 0.569
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.431 0.569
E80.1 Porphyria cutanea tarda
0.000 0.432 0.568
D07.1 Vulva
0.000 0.434 0.566
D03.1 Melanoma in situ of eyelid, including canthus
0.000 0.437 0.563
D02.4 Respiratory system, unspecified
0.000 0.438 0.562
D02.3 Other parts of respiratory system
0.000 0.438 0.562
D02.2 Bronchus and lung
0.000 0.438 0.562
D02.1 Trachea
0.000 0.438 0.562
C44.2 Skin of ear and external auricular canal
0.000 0.438 0.562
C07 Malignant neoplasm of parotid gland
0.000 0.439 0.561
D01.3 Anus and anal canal
0.000 0.441 0.558
E07 Other disorders of thyroid
0.000 0.443 0.557
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.444 0.555
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.444 0.555
E79.1 Lesch-Nyhan syndrome
0.000 0.444 0.555
E70.3 Albinism
0.000 0.447 0.553
G36.9 Acute disseminated demyelination, unspecified
0.551 0.449 0.000
G36.8 Other specified acute disseminated demyelination
0.551 0.449 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.551 0.449 0.000
C81 Hodgkin's disease
0.000 0.449 0.551
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.450 0.550
M11.9 Crystal arthropathy, unspecified
0.000 0.450 0.550
L55 Sunburn
0.000 0.450 0.550
E40-E46 Malnutrition
0.000 0.450 0.550
C02.9 Tongue, unspecified
0.000 0.451 0.549
E28.3 Primary ovarian failure
0.000 0.452 0.548
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.453 0.547
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.453 0.547
E80.4 Gilbert's syndrome
0.000 0.459 0.541
E84.9 Cystic fibrosis, unspecified
0.000 0.460 0.540
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.460 0.540
E13.8 With unspecified complications
0.000 0.461 0.539
E13.7 With multiple complications
0.000 0.461 0.539
E13.6 With other specified complications
0.000 0.461 0.539
E13.5 With peripheral circulatory complications
0.000 0.461 0.539
E13.4 With neurological complications
0.000 0.461 0.539
E13.3 With ophthalmic complications
0.000 0.461 0.539
E13.2 With renal complications
0.000 0.461 0.539
E13.1 With ketoacidosis
0.000 0.461 0.539
E13.0 With coma
0.000 0.461 0.539
C75 Malignant neoplasm of other endocrine glands and related structures
0.000 0.462 0.537
C05 Malignant neoplasm of palate
0.000 0.463 0.537
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.464 0.535
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.464 0.535
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.464 0.535
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.464 0.535
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.464 0.535
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.464 0.535
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.464 0.535
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.464 0.535
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.467 0.532
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.467 0.532
D07.6 Other and unspecified male genital organs
0.000 0.469 0.531
D07.3 Other and unspecified female genital organs
0.000 0.469 0.531
D03.6 Melanoma in situ of upper limb, including shoulder
0.000 0.470 0.530
L57.4 Cutis laxa senilis
0.000 0.470 0.530
D01.9 Digestive organ, unspecified
0.000 0.471 0.529
D01.7 Other specified digestive organs
0.000 0.471 0.529
D01.5 Liver, gallbladder and bile ducts
0.000 0.471 0.529
D01.4 Other and unspecified parts of intestine
0.000 0.471 0.529
D01.1 Rectosigmoid junction
0.000 0.471 0.529
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.471 0.528
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.471 0.528
E70.2 Disorders of tyrosine metabolism
0.000 0.471 0.528
E70.1 Other hyperphenylalaninaemias
0.000 0.471 0.528
E70.0 Classical phenylketonuria
0.000 0.471 0.528
E27.2 Addisonian crisis
0.000 0.476 0.524
E28.9 Ovarian dysfunction, unspecified
0.000 0.477 0.523
E28.8 Other ovarian dysfunction
0.000 0.477 0.523
E28.1 Androgen excess
0.000 0.477 0.523
E28.0 Oestrogen excess
0.000 0.477 0.523
E84.8 Cystic fibrosis with other manifestations
0.000 0.477 0.523
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.477 0.523
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.477 0.523
C43.4 Malignant melanoma of scalp and neck
0.000 0.477 0.523
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.478 0.522
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.478 0.522
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.478 0.522
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.478 0.522
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.478 0.522
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.478 0.522
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.478 0.522
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.478 0.522
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.478 0.522
L43.8 Other lichen planus
0.000 0.478 0.522
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.479 0.521
C04 Malignant neoplasm of floor of mouth
0.000 0.480 0.519
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.481 0.519
E80.5 Crigler-Najjar syndrome
0.000 0.481 0.519
E80.3 Defects of catalase and peroxydase
0.000 0.481 0.519
E80.0 Hereditary erythropoietic porphyria
0.000 0.481 0.519
L58 Radiodermatitis
0.000 0.481 0.518
C71.0 Cerebrum, except lobes and ventricles
0.000 0.484 0.516
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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