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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857197
log Bayes Factor = 49.995
Chromosome 6   position 32,746,984  (GRCh37) Explore rs2857197 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M07.3 Other psoriatic arthropathies
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
L57.0 Actinic keratosis
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
C44.7 Skin of lower limb, including hip
0.000 0.001 0.999
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.001 0.999
C44.6 Skin of upper limb, including shoulder
0.000 0.003 0.997
E20-E35 Disorders of other endocrine glands
0.000 0.003 0.997
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.003 0.997
L40.9 Psoriasis, unspecified
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.004 0.996
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
C44.3 Skin of other and unspecified parts of face
0.000 0.005 0.995
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.008 0.992
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.009 0.991
E23 Hypofunction and other disorders of pituitary gland
0.000 0.009 0.991
E10.9 Without complications
0.000 0.010 0.990
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.010 0.990
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.012 0.988
G35-G37 Demyelinating diseases of the central nervous system
0.985 0.015 0.000
E83.1 Disorders of iron metabolism
0.983 0.017 0.000
G37 Other demyelinating diseases of central nervous system
0.979 0.021 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.021 0.979
L40-L45 Papulosquamous disorders
0.000 0.024 0.976
E70-E90 Metabolic disorders
0.000 0.028 0.972
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.029 0.971
G37.9 Demyelinating disease of central nervous system, unspecified
0.971 0.029 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.032 0.968
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.036 0.964
E78.0 Pure hypercholesterolaemia
0.000 0.051 0.949
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.055 0.945
E27 Other disorders of adrenal gland
0.000 0.063 0.937
C44.4 Skin of scalp and neck
0.000 0.065 0.935
E23.6 Other disorders of pituitary gland
0.000 0.067 0.933
E11.3 With ophthalmic complications
0.000 0.068 0.932
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.069 0.931
E23.7 Disorder of pituitary gland, unspecified
0.000 0.073 0.927
C44.2 Skin of ear and external auricular canal
0.000 0.083 0.917
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.093 0.907
E78.5 Hyperlipidaemia, unspecified
0.000 0.098 0.902
E11.9 Without complications
0.000 0.102 0.898
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.106 0.894
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.114 0.886
C44.0 Skin of lip
0.000 0.118 0.882
E27.1 Primary adrenocortical insufficiency
0.000 0.119 0.881
E10.1 With ketoacidosis
0.000 0.119 0.881
E10.5 With peripheral circulatory complications
0.000 0.119 0.881
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.121 0.879
G37.8 Other specified demyelinating diseases of central nervous system
0.874 0.126 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.136 0.864
L43 Lichen planus
0.000 0.138 0.862
M06.0 Seronegative rheumatoid arthritis
0.000 0.152 0.848
E89.0 Postprocedural hypothyroidism
0.000 0.153 0.847
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.154 0.846
E06 Thyroiditis
0.000 0.155 0.845
E23.2 Diabetes insipidus
0.000 0.157 0.843
E10.0 With coma
0.000 0.162 0.838
E78.2 Mixed hyperlipidaemia
0.000 0.162 0.838
E28 Ovarian dysfunction
0.000 0.168 0.832
L40.1 Generalised pustular psoriasis
0.000 0.175 0.825
E78.6 Lipoprotein deficiency
0.000 0.180 0.820
E04 Other non-toxic goitre
0.000 0.182 0.818
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.190 0.810
E23.0 Hypopituitarism
0.000 0.197 0.803
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.198 0.802
L40.0 Psoriasis vulgaris
0.000 0.199 0.801
M06.3 Rheumatoid nodule
0.000 0.199 0.801
E78.1 Pure hyperglyceridaemia
0.000 0.202 0.798
G36 Other acute disseminated demyelination
0.798 0.202 0.000
M10 Gout
0.000 0.203 0.797
E11.2 With renal complications
0.000 0.207 0.793
E29 Testicular dysfunction
0.000 0.214 0.786
E10.2 With renal complications
0.000 0.214 0.786
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.220 0.780
E06.3 Autoimmune thyroiditis
0.000 0.222 0.778
E88 Other metabolic disorders
0.000 0.226 0.774
E24 Cushing's syndrome
0.000 0.228 0.772
E13 Other specified diabetes mellitus
0.000 0.228 0.772
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.230 0.770
L82 Seborrhoeic keratosis
0.000 0.232 0.768
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.233 0.767
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.244 0.756
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.245 0.755
D00-D09 In situ neoplasms
0.000 0.246 0.754
M06.4 Inflammatory polyarthropathy
0.000 0.247 0.753
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.249 0.751
Chapter II Neoplasms
0.000 0.251 0.749
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.252 0.748
D04 Carcinoma in situ of skin
0.000 0.253 0.747
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.254 0.746
E11.1 With ketoacidosis
0.000 0.256 0.744
D06 Carcinoma in situ of cervix uteri
0.000 0.259 0.741
E26 Hyperaldosteronism
0.000 0.260 0.740
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.261 0.739
E10.8 With unspecified complications
0.000 0.265 0.734
E84 Cystic fibrosis
0.000 0.266 0.734
E04.0 Non-toxic diffuse goitre
0.000 0.267 0.733
D06.9 Cervix, unspecified
0.000 0.268 0.732
L40.4 Guttate psoriasis
0.000 0.270 0.730
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.270 0.730
L42 Pityriasis rosea
0.000 0.274 0.726
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.275 0.725
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.276 0.724
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.276 0.724
L43.8 Other lichen planus
0.000 0.276 0.724
E89.3 Postprocedural hypopituitarism
0.000 0.279 0.721
L43.9 Lichen planus, unspecified
0.000 0.281 0.719
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.281 0.719
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M07.38 Other psoriatic arthropathies (Other)
0.000 0.283 0.717
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.283 0.717
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.283 0.717
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.283 0.717
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M07.6 Other enteropathic arthropathies
0.000 0.283 0.717
M07.5 Arthropathy in ulcerative colitis
0.000 0.283 0.717
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.283 0.717
M07.2 Psoriatic spondylitis
0.000 0.283 0.717
M07.1 Arthritis mutilans
0.000 0.283 0.717
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.284 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.284 0.716
M05.1 Rheumatoid lung disease
0.000 0.284 0.716
M05.0 Felty's syndrome
0.000 0.284 0.716
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.284 0.716
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.284 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.284 0.716
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.285 0.715
E32 Diseases of thymus
0.000 0.285 0.715
E31 Polyglandular dysfunction
0.000 0.285 0.715
E30 Disorders of puberty, not elsewhere classified
0.000 0.285 0.715
L85 Other epidermal thickening
0.000 0.285 0.715
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.285 0.715
E10.6 With other specified complications
0.000 0.287 0.713
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.287 0.712
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.288 0.712
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.290 0.710
E23.1 Drug-induced hypopituitarism
0.000 0.290 0.710
E79 Disorders of purine and pyrimidine metabolism
0.000 0.291 0.709
E05.8 Other thyrotoxicosis
0.000 0.292 0.708
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.293 0.707
E11.8 With unspecified complications
0.000 0.297 0.703
G37.5 Concentric sclerosis [Balo]
0.702 0.298 0.000
G37.4 Subacute necrotising myelitis
0.702 0.298 0.000
G37.2 Central pontine myelinolysis
0.702 0.298 0.000
G37.1 Central demyelination of corpus callosum
0.702 0.298 0.000
G37.0 Diffuse sclerosis
0.702 0.298 0.000
E10.4 With neurological complications
0.000 0.299 0.701
E28.2 Polycystic ovarian syndrome
0.000 0.300 0.700
L44 Other papulosquamous disorders
0.000 0.300 0.700
L41 Parapsoriasis
0.000 0.300 0.700
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.300 0.700
C83.3 Large cell (diffuse)
0.000 0.300 0.700
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.301 0.699
E77 Disorders of glycoprotein metabolism
0.000 0.303 0.697
E76 Disorders of glycosaminoglycan metabolism
0.000 0.303 0.697
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.303 0.697
E70 Disorders of aromatic amino-acid metabolism
0.000 0.303 0.697
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.303 0.697
E11.7 With multiple complications
0.000 0.306 0.694
L94 Other localised connective tissue disorders
0.000 0.308 0.692
L57.5 Actinic granuloma
0.000 0.308 0.691
L57.3 Poikiloderma of Civatte
0.000 0.308 0.691
L57.2 Cutis rhomboidalis nuchae
0.000 0.308 0.691
L57.1 Actinic reticuloid
0.000 0.308 0.691
M06.8 Other specified rheumatoid arthritis
0.000 0.309 0.691
L85.8 Other specified epidermal thickening
0.000 0.310 0.690
E27.9 Disorder of adrenal gland, unspecified
0.000 0.310 0.690
D04.5 Skin of trunk
0.000 0.311 0.689
E03.8 Other specified hypothyroidism
0.000 0.313 0.687
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.315 0.685
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.317 0.683
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.318 0.682
E03.1 Congenital hypothyroidism without goitre
0.000 0.318 0.682
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.319 0.681
E11.0 With coma
0.000 0.320 0.680
E20 Hypoparathyroidism
0.000 0.321 0.679
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.322 0.678
L55 Sunburn
0.000 0.322 0.678
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.324 0.676
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.325 0.675
E89.4 Postprocedural ovarian failure
0.000 0.327 0.673
D04.3 Skin of other and unspecified parts of face
0.000 0.328 0.672
E27.5 Adrenomedullary hyperfunction
0.000 0.328 0.672
E27.0 Other adrenocortical overactivity
0.000 0.328 0.672
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.332 0.668
M12 Other specific arthropathies
0.000 0.334 0.666
G36.0 Neuromyelitis optica [Devic]
0.664 0.336 0.000
E78.4 Other hyperlipidaemia
0.000 0.337 0.663
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.339 0.661
E25 Adrenogenital disorders
0.000 0.342 0.658
C43 Malignant melanoma of skin
0.000 0.343 0.657
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.346 0.654
C85.1 B-cell lymphoma, unspecified
0.000 0.350 0.650
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.350 0.650
E89.5 Postprocedural testicular hypofunction
0.000 0.350 0.650
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.649 0.351 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.351 0.648
E04.2 Non-toxic multinodular goitre
0.000 0.354 0.646
C73 Malignant neoplasm of thyroid gland
0.000 0.359 0.641
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.000 0.359 0.641
D04.7 Skin of lower limb, including hip
0.000 0.360 0.640
E29.1 Testicular hypofunction
0.000 0.366 0.634
E04.9 Non-toxic goitre, unspecified
0.000 0.367 0.633
M10.0 Idiopathic gout
0.000 0.367 0.633
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.368 0.632
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.368 0.632
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.369 0.631
E88.8 Other specified metabolic disorders
0.000 0.370 0.630
M05.2 Rheumatoid vasculitis
0.000 0.370 0.629
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.371 0.629
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.371 0.629
E89.1 Postprocedural hypoinsulinaemia
0.000 0.372 0.627
M11 Other crystal arthropathies
0.000 0.375 0.625
E11.6 With other specified complications
0.000 0.376 0.624
E89.2 Postprocedural hypoparathyroidism
0.000 0.376 0.624
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.378 0.622
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.378 0.622
E27.8 Other specified disorders of adrenal gland
0.000 0.378 0.622
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.378 0.622
L58 Radiodermatitis
0.000 0.378 0.621
E28.3 Primary ovarian failure
0.000 0.380 0.620
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.380 0.620
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.380 0.620
L94.2 Calcinosis cutis
0.000 0.380 0.620
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.380 0.620
E78.3 Hyperchylomicronaemia
0.000 0.381 0.619
L43.3 Subacute (active) lichen planus
0.000 0.382 0.618
L43.2 Lichenoid drug reaction
0.000 0.382 0.618
L43.1 Bullous lichen planus
0.000 0.382 0.618
L43.0 Hypertrophic lichen planus
0.000 0.382 0.618
D09 Carcinoma in situ of other and unspecified sites
0.000 0.382 0.618
D43.0 Brain, supratentorial
0.000 0.385 0.615
C91 Lymphoid leukaemia
0.000 0.388 0.612
M10.9 Gout, unspecified
0.000 0.389 0.611
M06.34 Rheumatoid nodule (Hand)
0.000 0.391 0.609
E13.9 Without complications
0.000 0.392 0.608
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.392 0.608
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.392 0.608
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.392 0.608
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.392 0.608
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.392 0.608
E06.5 Other chronic thyroiditis
0.000 0.394 0.606
E06.4 Drug-induced thyroiditis
0.000 0.394 0.606
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.394 0.606
E06.0 Acute thyroiditis
0.000 0.394 0.606
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.394 0.605
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.396 0.604
E74 Other disorders of carbohydrate metabolism
0.000 0.397 0.603
M14 Arthropathies in other diseases classified elsewhere
0.000 0.397 0.602
E06.9 Thyroiditis, unspecified
0.000 0.398 0.602
D04.2 Skin of ear and external auricular canal
0.000 0.399 0.601
D04.4 Skin of scalp and neck
0.000 0.400 0.600
E73 Lactose intolerance
0.000 0.401 0.599
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.402 0.598
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.403 0.597
E72 Other disorders of amino-acid metabolism
0.000 0.403 0.597
E21.3 Hyperparathyroidism, unspecified
0.000 0.403 0.597
E28.9 Ovarian dysfunction, unspecified
0.000 0.403 0.596
E28.8 Other ovarian dysfunction
0.000 0.403 0.596
E28.1 Androgen excess
0.000 0.403 0.596
E28.0 Oestrogen excess
0.000 0.403 0.596
L10-L14 Bullous disorders
0.000 0.404 0.596
E24.0 Pituitary-dependent Cushing's disease
0.000 0.408 0.592
E88.2 Lipomatosis, not elsewhere classified
0.000 0.409 0.590
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.410 0.590
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.412 0.588
E88.9 Metabolic disorder, unspecified
0.000 0.413 0.587
E04.8 Other specified non-toxic goitre
0.000 0.413 0.586
E80.4 Gilbert's syndrome
0.000 0.416 0.584
D04.9 Skin, unspecified
0.000 0.418 0.582
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.418 0.582
E78.8 Other disorders of lipoprotein metabolism
0.000 0.419 0.581
E85 Amyloidosis
0.000 0.419 0.581
D46 Myelodysplastic syndromes
0.000 0.420 0.580
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.421 0.579
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.426 0.574
M06.38 Rheumatoid nodule (Other)
0.000 0.426 0.574
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.426 0.574
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.426 0.574
M06.33 Rheumatoid nodule (Forearm)
0.000 0.426 0.574
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.426 0.574
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.426 0.574
E24.9 Cushing's syndrome, unspecified
0.000 0.427 0.573
G36.9 Acute disseminated demyelination, unspecified
0.572 0.428 0.000
G36.8 Other specified acute disseminated demyelination
0.572 0.428 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.572 0.428 0.000
M10.4 Other secondary gout
0.000 0.428 0.572
M10.2 Drug-induced gout
0.000 0.428 0.572
M10.1 Lead-induced gout
0.000 0.428 0.572
L57.4 Cutis laxa senilis
0.000 0.430 0.570
E84.9 Cystic fibrosis, unspecified
0.000 0.436 0.564
E29.9 Testicular dysfunction, unspecified
0.000 0.436 0.563
E29.8 Other testicular dysfunction
0.000 0.436 0.563
E29.0 Testicular hyperfunction
0.000 0.436 0.563
E21.0 Primary hyperparathyroidism
0.000 0.437 0.563
L94.0 Localised scleroderma [morphea]
0.000 0.439 0.561
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.439 0.560
E21.4 Other specified disorders of parathyroid gland
0.000 0.440 0.559
E11.5 With peripheral circulatory complications
0.000 0.440 0.560
C83.1 Small cleaved cell (diffuse)
0.000 0.442 0.558
E24.2 Drug-induced Cushing's syndrome
0.000 0.443 0.556
E27.2 Addisonian crisis
0.000 0.444 0.556
E26.0 Primary hyperaldosteronism
0.000 0.444 0.556
C83.7 Burkitt's tumour
0.000 0.445 0.555
M10.3 Gout due to impairment of renal function
0.000 0.445 0.555
E88.3 Tumour lysis syndrome
0.000 0.445 0.555
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.000 0.446 0.554
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.446 0.554
E24.8 Other Cushing's syndrome
0.000 0.446 0.553
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.446 0.553
E24.3 Ectopic ACTH syndrome
0.000 0.446 0.553
E24.1 Nelson's syndrome
0.000 0.446 0.553
E13.8 With unspecified complications
0.000 0.447 0.553
E13.7 With multiple complications
0.000 0.447 0.553
E13.6 With other specified complications
0.000 0.447 0.553
E13.5 With peripheral circulatory complications
0.000 0.447 0.553
E13.4 With neurological complications
0.000 0.447 0.553
E13.3 With ophthalmic complications
0.000 0.447 0.553
E13.2 With renal complications
0.000 0.447 0.553
E13.1 With ketoacidosis
0.000 0.447 0.553
E13.0 With coma
0.000 0.447 0.553
L87 Transepidermal elimination disorders
0.000 0.448 0.552
L86 Keratoderma in diseases classified elsewhere
0.000 0.448 0.552
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.448 0.552
D03 Melanoma in situ
0.000 0.449 0.551
C82.0 Small cleaved cell, follicular
0.000 0.451 0.549
L80 Vitiligo
0.000 0.452 0.548
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.452 0.548
E21.2 Other hyperparathyroidism
0.000 0.454 0.546
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.455 0.544
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.456 0.544
L56.3 Solar urticaria
0.000 0.458 0.542
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.458 0.542
L56.1 Drug photoallergic response
0.000 0.458 0.542
L56.0 Drug phototoxic response
0.000 0.458 0.542
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.458 0.542
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.460 0.540
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.460 0.540
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.460 0.540
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.460 0.540
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.460 0.540
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.460 0.540
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.460 0.540
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.460 0.540
C91.9 Lymphoid leukaemia, unspecified
0.000 0.463 0.537
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.464 0.536
C94 Other leukaemias of specified cell type
0.000 0.464 0.536
D06.0 Endocervix
0.000 0.464 0.536
D04.8 Skin of other sites
0.000 0.465 0.535
D04.0 Skin of lip
0.000 0.465 0.535
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.465 0.535
M10.90 Gout, unspecified (Multiple sites)
0.000 0.466 0.534
D06.7 Other parts of cervix
0.000 0.469 0.531
D06.1 Exocervix
0.000 0.469 0.531
E26.9 Hyperaldosteronism, unspecified
0.000 0.469 0.531
E26.8 Other hyperaldosteronism
0.000 0.469 0.531
E26.1 Secondary hyperaldosteronism
0.000 0.469 0.531
E80.1 Porphyria cutanea tarda
0.000 0.469 0.531
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.470 0.530
C85.0 Lymphosarcoma
0.000 0.470 0.530
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.472 0.528
L92.0 Granuloma annulare
0.000 0.473 0.527
E84.8 Cystic fibrosis with other manifestations
0.000 0.474 0.526
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.474 0.526
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.474 0.526
E80.6 Other disorders of bilirubin metabolism
0.000 0.474 0.526
C12 Malignant neoplasm of pyriform sinus
0.000 0.476 0.524
C86 Other specified types of T/NK-cell lymphoma
0.000 0.477 0.523
D47.1 Chronic myeloproliferative disease
0.000 0.478 0.522
C93 Monocytic leukaemia
0.000 0.478 0.522
E40-E46 Malnutrition
0.000 0.479 0.521
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.479 0.521
L83 Acanthosis nigricans
0.000 0.479 0.520
C44.5 Skin of trunk
0.000 0.483 0.517
C88 Malignant immunoproliferative diseases
0.000 0.484 0.516
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.484 0.516
E80.5 Crigler-Najjar syndrome
0.000 0.484 0.516
E80.3 Defects of catalase and peroxydase
0.000 0.484 0.516
E80.0 Hereditary erythropoietic porphyria
0.000 0.484 0.516
D47.2 Monoclonal gammopathy
0.000 0.486 0.514
M10.09 Idiopathic gout (Site unspecified)
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M08.9 Juvenile arthritis, unspecified
0.000 0.486 0.514
M08.8 Other juvenile arthritis
0.000 0.486 0.514
M08.4 Pauciarticular juvenile arthritis
0.000 0.486 0.514
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.486 0.514
M08.2 Juvenile arthritis with systemic onset
0.000 0.486 0.514
M08.1 Juvenile ankylosing spondylitis
0.000 0.486 0.514
M08.0 Juvenile rheumatoid arthritis
0.000 0.486 0.514
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.486 0.514
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.486 0.514
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.486 0.514
M09.0 Juvenile arthritis in psoriasis
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.000 0.486 0.514
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.000 0.486 0.514
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.000 0.486 0.514
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.000 0.486 0.514
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.000 0.486 0.514
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.000 0.486 0.514
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.000 0.486 0.514
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.000 0.486 0.514
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.000 0.486 0.514
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.000 0.486 0.514
M07.19 Arthritis mutilans (Site unspecified)
0.000 0.486 0.514
M07.18 Arthritis mutilans (Other)
0.000 0.486 0.514
M07.17 Arthritis mutilans (Ankle and foot)
0.000 0.486 0.514
M07.16 Arthritis mutilans (Lower leg)
0.000 0.486 0.514
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.000 0.486 0.514
M07.14 Arthritis mutilans (Hand)
0.000 0.486 0.514
M07.13 Arthritis mutilans (Forearm)
0.000 0.486 0.514
M07.12 Arthritis mutilans (Upper arm)
0.000 0.486 0.514
M07.11 Arthritis mutilans (Shoulder region)
0.000 0.486 0.514
M07.10 Arthritis mutilans (Multiple sites)
0.000 0.486 0.514
M07.29 Psoriatic spondylitis (Site unspecified)
0.000 0.486 0.514
M07.28 Psoriatic spondylitis (Other)
0.000 0.486 0.514
M07.27 Psoriatic spondylitis (Ankle and foot)
0.000 0.486 0.514
M07.26 Psoriatic spondylitis (Lower leg)
0.000 0.486 0.514
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.000 0.486 0.514
M07.24 Psoriatic spondylitis (Hand)
0.000 0.486 0.514
M07.23 Psoriatic spondylitis (Forearm)
0.000 0.486 0.514
M07.22 Psoriatic spondylitis (Upper arm)
0.000 0.486 0.514
M07.21 Psoriatic spondylitis (Shoulder region)
0.000 0.486 0.514
M07.20 Psoriatic spondylitis (Multiple sites)
0.000 0.486 0.514
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.000 0.486 0.514
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.000 0.486 0.514
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.000 0.486 0.514
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.000 0.486 0.514
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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