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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857205
log Bayes Factor = 48.8877
Chromosome 6   position 32,744,145  (GRCh37) Explore rs2857205 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M07.3 Other psoriatic arthropathies
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L57.0 Actinic keratosis
0.000 0.001 0.999
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
C44.7 Skin of lower limb, including hip
0.000 0.001 0.999
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.000 0.002 0.998
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.003 0.997
C44.6 Skin of upper limb, including shoulder
0.000 0.004 0.996
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
E20-E35 Disorders of other endocrine glands
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.004 0.996
C44.3 Skin of other and unspecified parts of face
0.000 0.007 0.993
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.007 0.993
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.009 0.991
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.010 0.990
E10.9 Without complications
0.000 0.011 0.989
E23 Hypofunction and other disorders of pituitary gland
0.000 0.011 0.989
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.012 0.988
G35-G37 Demyelinating diseases of the central nervous system
0.988 0.012 0.000
E83.1 Disorders of iron metabolism
0.985 0.015 0.000
G37 Other demyelinating diseases of central nervous system
0.984 0.016 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.020 0.980
G37.9 Demyelinating disease of central nervous system, unspecified
0.977 0.023 0.000
E70-E90 Metabolic disorders
0.000 0.030 0.970
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.030 0.970
L40-L45 Papulosquamous disorders
0.000 0.036 0.964
E11 Non-insulin-dependent diabetes mellitus
0.000 0.040 0.960
E78.0 Pure hypercholesterolaemia
0.000 0.049 0.951
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.057 0.943
C44.2 Skin of ear and external auricular canal
0.000 0.065 0.935
C44.4 Skin of scalp and neck
0.000 0.068 0.932
E23.6 Other disorders of pituitary gland
0.000 0.069 0.931
E11.3 With ophthalmic complications
0.000 0.074 0.926
E23.7 Disorder of pituitary gland, unspecified
0.000 0.074 0.926
E27 Other disorders of adrenal gland
0.000 0.083 0.917
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.087 0.913
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.098 0.902
C44.0 Skin of lip
0.000 0.106 0.894
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.109 0.891
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.109 0.891
E78.5 Hyperlipidaemia, unspecified
0.000 0.110 0.890
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.114 0.886
E10.5 With peripheral circulatory complications
0.000 0.119 0.881
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.121 0.879
E06 Thyroiditis
0.000 0.132 0.868
G37.8 Other specified demyelinating diseases of central nervous system
0.861 0.139 0.000
L43 Lichen planus
0.000 0.140 0.860
E11.9 Without complications
0.000 0.144 0.856
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.146 0.854
E27.1 Primary adrenocortical insufficiency
0.000 0.146 0.854
M06.0 Seronegative rheumatoid arthritis
0.000 0.151 0.849
E23.2 Diabetes insipidus
0.000 0.151 0.849
E10.1 With ketoacidosis
0.000 0.152 0.848
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.153 0.847
M10 Gout
0.000 0.158 0.842
E89.0 Postprocedural hypothyroidism
0.000 0.161 0.839
E10.0 With coma
0.000 0.162 0.838
E78.2 Mixed hyperlipidaemia
0.000 0.163 0.837
E28 Ovarian dysfunction
0.000 0.168 0.831
L40.1 Generalised pustular psoriasis
0.000 0.175 0.825
E04 Other non-toxic goitre
0.000 0.180 0.820
E78.6 Lipoprotein deficiency
0.000 0.181 0.819
E06.3 Autoimmune thyroiditis
0.000 0.189 0.811
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.190 0.810
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.198 0.802
M06.3 Rheumatoid nodule
0.000 0.198 0.802
L40.0 Psoriasis vulgaris
0.000 0.198 0.802
G36 Other acute disseminated demyelination
0.800 0.199 0.000
E78.1 Pure hyperglyceridaemia
0.000 0.203 0.797
E88 Other metabolic disorders
0.000 0.204 0.796
E11.2 With renal complications
0.000 0.212 0.788
E10.2 With renal complications
0.000 0.214 0.786
E29 Testicular dysfunction
0.000 0.215 0.785
E23.0 Hypopituitarism
0.000 0.218 0.782
E13 Other specified diabetes mellitus
0.000 0.228 0.772
E24 Cushing's syndrome
0.000 0.229 0.771
M06.4 Inflammatory polyarthropathy
0.000 0.232 0.768
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.233 0.767
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.252 0.748
D00-D09 In situ neoplasms
0.000 0.255 0.745
Chapter II Neoplasms
0.000 0.259 0.741
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.259 0.740
E26 Hyperaldosteronism
0.000 0.261 0.739
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.261 0.739
E11.1 With ketoacidosis
0.000 0.262 0.738
D04 Carcinoma in situ of skin
0.000 0.263 0.737
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.263 0.737
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.264 0.736
E10.8 With unspecified complications
0.000 0.265 0.735
E04.0 Non-toxic diffuse goitre
0.000 0.266 0.734
E84 Cystic fibrosis
0.000 0.267 0.733
D06 Carcinoma in situ of cervix uteri
0.000 0.269 0.731
L40.4 Guttate psoriasis
0.000 0.270 0.730
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.270 0.730
L43.9 Lichen planus, unspecified
0.000 0.272 0.728
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.274 0.725
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.275 0.725
L43.8 Other lichen planus
0.000 0.278 0.722
D06.9 Cervix, unspecified
0.000 0.279 0.721
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.279 0.721
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.281 0.719
L42 Pityriasis rosea
0.000 0.282 0.718
E89.3 Postprocedural hypopituitarism
0.000 0.282 0.718
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M07.38 Other psoriatic arthropathies (Other)
0.000 0.283 0.717
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.283 0.717
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.283 0.717
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M07.6 Other enteropathic arthropathies
0.000 0.283 0.717
M07.5 Arthropathy in ulcerative colitis
0.000 0.283 0.717
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.283 0.717
M07.2 Psoriatic spondylitis
0.000 0.283 0.717
M07.1 Arthritis mutilans
0.000 0.283 0.717
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.283 0.717
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.284 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.284 0.716
M05.1 Rheumatoid lung disease
0.000 0.284 0.716
M05.0 Felty's syndrome
0.000 0.284 0.716
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.284 0.716
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.284 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.284 0.716
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.286 0.714
E32 Diseases of thymus
0.000 0.286 0.714
E31 Polyglandular dysfunction
0.000 0.286 0.714
E30 Disorders of puberty, not elsewhere classified
0.000 0.286 0.714
E10.6 With other specified complications
0.000 0.287 0.713
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.287 0.713
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.288 0.712
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.291 0.709
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.291 0.709
E23.1 Drug-induced hypopituitarism
0.000 0.291 0.709
E05.8 Other thyrotoxicosis
0.000 0.292 0.708
E79 Disorders of purine and pyrimidine metabolism
0.000 0.292 0.708
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.293 0.707
G37.5 Concentric sclerosis [Balo]
0.705 0.295 0.000
G37.4 Subacute necrotising myelitis
0.705 0.295 0.000
G37.2 Central pontine myelinolysis
0.705 0.295 0.000
G37.1 Central demyelination of corpus callosum
0.705 0.295 0.000
G37.0 Diffuse sclerosis
0.705 0.295 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.296 0.704
E11.0 With coma
0.000 0.299 0.701
E28.2 Polycystic ovarian syndrome
0.000 0.300 0.700
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.301 0.699
E11.8 With unspecified complications
0.000 0.303 0.697
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.304 0.696
C83.3 Large cell (diffuse)
0.000 0.304 0.696
E77 Disorders of glycoprotein metabolism
0.000 0.304 0.696
E76 Disorders of glycosaminoglycan metabolism
0.000 0.304 0.696
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.304 0.696
E70 Disorders of aromatic amino-acid metabolism
0.000 0.304 0.696
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.304 0.696
L44 Other papulosquamous disorders
0.000 0.308 0.691
L41 Parapsoriasis
0.000 0.308 0.691
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.308 0.691
M06.8 Other specified rheumatoid arthritis
0.000 0.309 0.691
M10.0 Idiopathic gout
0.000 0.310 0.690
E11.7 With multiple complications
0.000 0.312 0.688
E03.8 Other specified hypothyroidism
0.000 0.312 0.687
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.317 0.682
E03.1 Congenital hypothyroidism without goitre
0.000 0.318 0.682
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.319 0.681
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.320 0.680
M10.9 Gout, unspecified
0.000 0.322 0.678
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.322 0.678
E20 Hypoparathyroidism
0.000 0.323 0.677
D04.5 Skin of trunk
0.000 0.323 0.677
L57.5 Actinic granuloma
0.000 0.324 0.676
L57.3 Poikiloderma of Civatte
0.000 0.324 0.676
L57.2 Cutis rhomboidalis nuchae
0.000 0.324 0.676
L57.1 Actinic reticuloid
0.000 0.324 0.676
E27.9 Disorder of adrenal gland, unspecified
0.000 0.325 0.675
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.326 0.674
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.327 0.673
E89.4 Postprocedural ovarian failure
0.000 0.330 0.670
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.330 0.670
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.331 0.669
M12 Other specific arthropathies
0.000 0.333 0.666
G36.0 Neuromyelitis optica [Devic]
0.666 0.334 0.000
D04.3 Skin of other and unspecified parts of face
0.000 0.335 0.665
E10.4 With neurological complications
0.000 0.336 0.664
E78.4 Other hyperlipidaemia
0.000 0.337 0.663
E27.5 Adrenomedullary hyperfunction
0.000 0.342 0.658
E27.0 Other adrenocortical overactivity
0.000 0.342 0.658
E25 Adrenogenital disorders
0.000 0.343 0.656
L55 Sunburn
0.000 0.345 0.655
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.652 0.348 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.349 0.651
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.000 0.349 0.651
E04.2 Non-toxic multinodular goitre
0.000 0.350 0.650
E88.8 Other specified metabolic disorders
0.000 0.352 0.648
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.353 0.647
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.353 0.647
E89.5 Postprocedural testicular hypofunction
0.000 0.353 0.647
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.355 0.645
C85.1 B-cell lymphoma, unspecified
0.000 0.357 0.643
L82 Seborrhoeic keratosis
0.000 0.359 0.641
C73 Malignant neoplasm of thyroid gland
0.000 0.365 0.635
E29.1 Testicular hypofunction
0.000 0.367 0.633
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.367 0.633
D04.7 Skin of lower limb, including hip
0.000 0.367 0.633
E04.9 Non-toxic goitre, unspecified
0.000 0.367 0.633
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.368 0.632
C43 Malignant melanoma of skin
0.000 0.368 0.632
M05.2 Rheumatoid vasculitis
0.000 0.370 0.630
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.370 0.630
D43.0 Brain, supratentorial
0.000 0.375 0.625
E89.1 Postprocedural hypoinsulinaemia
0.000 0.376 0.624
E06.5 Other chronic thyroiditis
0.000 0.377 0.622
E06.4 Drug-induced thyroiditis
0.000 0.377 0.622
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.377 0.622
E06.0 Acute thyroiditis
0.000 0.377 0.622
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.378 0.621
E89.2 Postprocedural hypoparathyroidism
0.000 0.379 0.621
M11 Other crystal arthropathies
0.000 0.379 0.621
E28.3 Primary ovarian failure
0.000 0.380 0.620
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.380 0.620
E11.6 With other specified complications
0.000 0.381 0.619
E06.9 Thyroiditis, unspecified
0.000 0.381 0.619
E78.3 Hyperchylomicronaemia
0.000 0.382 0.618
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.383 0.617
L43.3 Subacute (active) lichen planus
0.000 0.383 0.616
L43.2 Lichenoid drug reaction
0.000 0.383 0.616
L43.1 Bullous lichen planus
0.000 0.383 0.616
L43.0 Hypertrophic lichen planus
0.000 0.383 0.616
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.388 0.612
D09 Carcinoma in situ of other and unspecified sites
0.000 0.388 0.612
M06.34 Rheumatoid nodule (Hand)
0.000 0.390 0.610
E13.9 Without complications
0.000 0.391 0.609
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.391 0.609
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.391 0.609
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.391 0.609
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.391 0.609
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.391 0.609
E88.2 Lipomatosis, not elsewhere classified
0.000 0.393 0.607
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.393 0.607
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.394 0.606
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.395 0.605
M10.4 Other secondary gout
0.000 0.396 0.604
M10.2 Drug-induced gout
0.000 0.396 0.604
M10.1 Lead-induced gout
0.000 0.396 0.604
E88.9 Metabolic disorder, unspecified
0.000 0.396 0.604
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.398 0.602
L58 Radiodermatitis
0.000 0.399 0.600
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.401 0.599
E73 Lactose intolerance
0.000 0.401 0.598
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.402 0.598
E28.9 Ovarian dysfunction, unspecified
0.000 0.404 0.596
E28.8 Other ovarian dysfunction
0.000 0.404 0.596
E28.1 Androgen excess
0.000 0.404 0.596
E28.0 Oestrogen excess
0.000 0.404 0.596
E72 Other disorders of amino-acid metabolism
0.000 0.404 0.596
C91 Lymphoid leukaemia
0.000 0.405 0.595
D04.2 Skin of ear and external auricular canal
0.000 0.407 0.593
E27.8 Other specified disorders of adrenal gland
0.000 0.407 0.593
D04.4 Skin of scalp and neck
0.000 0.407 0.593
M10.90 Gout, unspecified (Multiple sites)
0.000 0.407 0.593
E74 Other disorders of carbohydrate metabolism
0.000 0.409 0.591
E24.0 Pituitary-dependent Cushing's disease
0.000 0.409 0.591
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.409 0.591
E04.8 Other specified non-toxic goitre
0.000 0.412 0.588
M10.3 Gout due to impairment of renal function
0.000 0.413 0.587
L85 Other epidermal thickening
0.000 0.414 0.586
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.415 0.585
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.416 0.584
L10-L14 Bullous disorders
0.000 0.417 0.583
E85 Amyloidosis
0.000 0.419 0.581
L94 Other localised connective tissue disorders
0.000 0.420 0.580
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.420 0.580
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.425 0.575
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.425 0.575
M06.38 Rheumatoid nodule (Other)
0.000 0.425 0.575
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.425 0.575
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.425 0.575
M06.33 Rheumatoid nodule (Forearm)
0.000 0.425 0.575
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.425 0.575
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.425 0.575
D04.9 Skin, unspecified
0.000 0.425 0.575
G36.9 Acute disseminated demyelination, unspecified
0.574 0.426 0.000
G36.8 Other specified acute disseminated demyelination
0.574 0.426 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.574 0.426 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.427 0.573
D46 Myelodysplastic syndromes
0.000 0.428 0.572
E88.3 Tumour lysis syndrome
0.000 0.429 0.570
M14 Arthropathies in other diseases classified elsewhere
0.000 0.434 0.565
E84.9 Cystic fibrosis, unspecified
0.000 0.437 0.563
E29.9 Testicular dysfunction, unspecified
0.000 0.437 0.562
E29.8 Other testicular dysfunction
0.000 0.437 0.562
E29.0 Testicular hyperfunction
0.000 0.437 0.562
M10.09 Idiopathic gout (Site unspecified)
0.000 0.439 0.561
L85.8 Other specified epidermal thickening
0.000 0.439 0.561
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.000 0.440 0.560
L57.4 Cutis laxa senilis
0.000 0.442 0.558
E24.2 Drug-induced Cushing's syndrome
0.000 0.444 0.556
E11.5 With peripheral circulatory complications
0.000 0.444 0.556
E26.0 Primary hyperaldosteronism
0.000 0.445 0.555
E21.3 Hyperparathyroidism, unspecified
0.000 0.445 0.555
E13.8 With unspecified complications
0.000 0.446 0.554
E13.7 With multiple complications
0.000 0.446 0.554
E13.6 With other specified complications
0.000 0.446 0.554
E13.5 With peripheral circulatory complications
0.000 0.446 0.554
E13.4 With neurological complications
0.000 0.446 0.554
E13.3 With ophthalmic complications
0.000 0.446 0.554
E13.2 With renal complications
0.000 0.446 0.554
E13.1 With ketoacidosis
0.000 0.446 0.554
E13.0 With coma
0.000 0.446 0.554
E24.8 Other Cushing's syndrome
0.000 0.447 0.553
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.447 0.553
E24.3 Ectopic ACTH syndrome
0.000 0.447 0.553
E24.1 Nelson's syndrome
0.000 0.447 0.553
E78.8 Other disorders of lipoprotein metabolism
0.000 0.447 0.553
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.449 0.551
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.449 0.551
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.449 0.551
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.449 0.551
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.449 0.551
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.449 0.551
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.449 0.551
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.449 0.551
C83.7 Burkitt's tumour
0.000 0.450 0.550
C82.0 Small cleaved cell, follicular
0.000 0.452 0.548
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.453 0.547
D03 Melanoma in situ
0.000 0.453 0.547
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.454 0.545
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.454 0.546
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.458 0.542
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.464 0.535
C83.1 Small cleaved cell (diffuse)
0.000 0.466 0.534
E26.9 Hyperaldosteronism, unspecified
0.000 0.470 0.530
E26.8 Other hyperaldosteronism
0.000 0.470 0.530
E26.1 Secondary hyperaldosteronism
0.000 0.470 0.530
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.470 0.530
C94 Other leukaemias of specified cell type
0.000 0.470 0.530
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.471 0.529
D47.1 Chronic myeloproliferative disease
0.000 0.471 0.529
D06.0 Endocervix
0.000 0.471 0.529
D04.8 Skin of other sites
0.000 0.471 0.529
D04.0 Skin of lip
0.000 0.471 0.529
E21.4 Other specified disorders of parathyroid gland
0.000 0.472 0.528
M13 Other arthritis
0.000 0.472 0.528
E84.8 Cystic fibrosis with other manifestations
0.000 0.474 0.525
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.474 0.525
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.474 0.525
D06.7 Other parts of cervix
0.000 0.476 0.524
D06.1 Exocervix
0.000 0.476 0.524
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.477 0.523
C85.0 Lymphosarcoma
0.000 0.477 0.523
C91.9 Lymphoid leukaemia, unspecified
0.000 0.477 0.523
E40-E46 Malnutrition
0.000 0.478 0.521
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.479 0.521
D43.2 Brain, unspecified
0.000 0.480 0.520
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.480 0.520
L94.2 Calcinosis cutis
0.000 0.480 0.520
D47.2 Monoclonal gammopathy
0.000 0.483 0.517
L56.3 Solar urticaria
0.000 0.483 0.517
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.483 0.517
L56.1 Drug photoallergic response
0.000 0.483 0.517
L56.0 Drug phototoxic response
0.000 0.483 0.517
C93 Monocytic leukaemia
0.000 0.484 0.516
E21.2 Other hyperparathyroidism
0.000 0.485 0.515
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M08.9 Juvenile arthritis, unspecified
0.000 0.486 0.514
M08.8 Other juvenile arthritis
0.000 0.486 0.514
M08.4 Pauciarticular juvenile arthritis
0.000 0.486 0.514
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.486 0.514
M08.2 Juvenile arthritis with systemic onset
0.000 0.486 0.514
M08.1 Juvenile ankylosing spondylitis
0.000 0.486 0.514
M08.0 Juvenile rheumatoid arthritis
0.000 0.486 0.514
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.486 0.514
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.486 0.514
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.486 0.514
M09.0 Juvenile arthritis in psoriasis
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.000 0.486 0.514
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.000 0.486 0.514
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.000 0.486 0.514
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.000 0.486 0.514
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.000 0.486 0.514
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.000 0.486 0.514
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.000 0.486 0.514
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.000 0.486 0.514
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.000 0.486 0.514
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.000 0.486 0.514
M07.19 Arthritis mutilans (Site unspecified)
0.000 0.486 0.514
M07.18 Arthritis mutilans (Other)
0.000 0.486 0.514
M07.17 Arthritis mutilans (Ankle and foot)
0.000 0.486 0.514
M07.16 Arthritis mutilans (Lower leg)
0.000 0.486 0.514
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.000 0.486 0.514
M07.14 Arthritis mutilans (Hand)
0.000 0.486 0.514
M07.13 Arthritis mutilans (Forearm)
0.000 0.486 0.514
M07.12 Arthritis mutilans (Upper arm)
0.000 0.486 0.514
M07.11 Arthritis mutilans (Shoulder region)
0.000 0.486 0.514
M07.10 Arthritis mutilans (Multiple sites)
0.000 0.486 0.514
M07.29 Psoriatic spondylitis (Site unspecified)
0.000 0.486 0.514
M07.28 Psoriatic spondylitis (Other)
0.000 0.486 0.514
M07.27 Psoriatic spondylitis (Ankle and foot)
0.000 0.486 0.514
M07.26 Psoriatic spondylitis (Lower leg)
0.000 0.486 0.514
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.000 0.486 0.514
M07.24 Psoriatic spondylitis (Hand)
0.000 0.486 0.514
M07.23 Psoriatic spondylitis (Forearm)
0.000 0.486 0.514
M07.22 Psoriatic spondylitis (Upper arm)
0.000 0.486 0.514
M07.21 Psoriatic spondylitis (Shoulder region)
0.000 0.486 0.514
M07.20 Psoriatic spondylitis (Multiple sites)
0.000 0.486 0.514
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.000 0.486 0.514
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.000 0.486 0.514
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.000 0.486 0.514
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.000 0.486 0.514
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.000 0.486 0.514
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.000 0.486 0.514
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.000 0.486 0.514
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.000 0.486 0.514
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.000 0.486 0.514
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.000 0.486 0.514
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.000 0.486 0.514
M07.58 Arthropathy in ulcerative colitis (Other)
0.000 0.486 0.514
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.000 0.486 0.514
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.000 0.486 0.514
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.000 0.486 0.514
M07.54 Arthropathy in ulcerative colitis (Hand)
0.000 0.486 0.514
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.000 0.486 0.514
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.000 0.486 0.514
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.000 0.486 0.514
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.000 0.486 0.514
M07.69 Other enteropathic arthropathies (Site unspecified)
0.000 0.486 0.514
M07.68 Other enteropathic arthropathies (Other)
0.000 0.486 0.514
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.000 0.486 0.514
M07.66 Other enteropathic arthropathies (Lower leg)
0.000 0.486 0.514
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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