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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857281
log Bayes Factor = 9.00838
Chromosome 6   position 31,374,262  (GRCh37) Explore rs2857281 on Ensembl!
Variant rs2857281 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.001 0.999
# Top node
0.000 0.002 0.998
L40-L45 Papulosquamous disorders
0.000 0.003 0.997
L40 Psoriasis
0.000 0.004 0.996
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.005 0.995
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.007 0.993
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.009 0.991
E65-E68 Obesity and other hyperalimentation
0.000 0.010 0.990
M06.9 Rheumatoid arthritis, unspecified
0.000 0.010 0.990
M06 Other rheumatoid arthritis
0.000 0.013 0.987
L40.5 Arthropathic psoriasis
0.000 0.013 0.987
L40.9 Psoriasis, unspecified
0.000 0.014 0.986
M05-M14 Inflammatory polyarthropathies
0.000 0.014 0.986
D50-D53 Nutritional anaemias
0.000 0.015 0.985
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.016 0.984
L57.0 Actinic keratosis
0.000 0.016 0.984
E66 Obesity
0.000 0.017 0.983
D50 Iron deficiency anaemia
0.000 0.018 0.982
E66.8 Other obesity
0.000 0.019 0.981
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.020 0.980
D50.9 Iron deficiency anaemia, unspecified
0.000 0.021 0.979
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.021 0.979
Chapter VIII Diseases of the ear and mastoid process
0.000 0.042 0.958
Chapter I Certain infectious and parasitic diseases
0.000 0.043 0.957
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.045 0.955
E70-E90 Metabolic disorders
0.000 0.051 0.949
B35-B49 Mycoses
0.000 0.055 0.945
B37 Candidiasis
0.000 0.058 0.942
B37.8 Candidiasis of other sites
0.000 0.061 0.939
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.066 0.934
H65-H75 Diseases of middle ear and mastoid
0.000 0.072 0.928
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.078 0.922
L20-L30 Dermatitis and eczema
0.000 0.084 0.916
H72 Perforation of tympanic membrane
0.000 0.086 0.914
B25-B34 Other viral diseases
0.000 0.089 0.911
E06 Thyroiditis
0.000 0.092 0.908
H72.9 Perforation of tympanic membrane, unspecified
0.000 0.095 0.905
M07 Psoriatic and enteropathic arthropathies
0.000 0.096 0.904
M45-M49 Spondylopathies
0.000 0.099 0.901
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.103 0.897
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.103 0.897
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.108 0.892
M45 Ankylosing spondylitis
0.000 0.110 0.890
E10-E14 Diabetes mellitus
0.000 0.111 0.889
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.125 0.875
B34 Viral infection of unspecified site
0.000 0.127 0.873
B37.0 Candidal stomatitis
0.000 0.133 0.867
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.136 0.864
E10 Insulin-dependent diabetes mellitus
0.000 0.138 0.862
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.149 0.851
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.149 0.851
M35 Other systemic involvement of connective tissue
0.000 0.153 0.847
H65 Nonsuppurative otitis media
0.000 0.154 0.846
M07.3 Other psoriatic arthropathies
0.000 0.155 0.845
M35.3 Polymyalgia rheumatica
0.000 0.155 0.845
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.156 0.844
M20-M25 Other joint disorders
0.000 0.156 0.844
H80-H83 Diseases of inner ear
0.000 0.160 0.840
Chapter V Mental and behavioural disorders
0.000 0.161 0.839
M05 Seropositive rheumatoid arthritis
0.000 0.165 0.835
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.167 0.833
B34.9 Viral infection, unspecified
0.000 0.169 0.831
E06.3 Autoimmune thyroiditis
0.000 0.169 0.831
D68 Other coagulation defects
0.000 0.172 0.828
D80-D89 Certain disorders involving the immune mechanism
0.000 0.177 0.823
M95.0 Acquired deformity of nose
0.000 0.178 0.822
L29 Pruritus
0.000 0.181 0.819
E89.0 Postprocedural hypothyroidism
0.000 0.187 0.813
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.188 0.812
E20-E35 Disorders of other endocrine glands
0.000 0.192 0.808
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.202 0.798
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.206 0.793
M06.0 Seronegative rheumatoid arthritis
0.000 0.207 0.793
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.207 0.793
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.212 0.788
L08 Other local infections of skin and subcutaneous tissue
0.000 0.215 0.785
E86 Volume depletion
0.000 0.217 0.783
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.219 0.781
E27 Other disorders of adrenal gland
0.000 0.223 0.777
L29.0 Pruritus ani
0.000 0.223 0.777
E10.9 Without complications
0.000 0.230 0.770
B35 Dermatophytosis
0.000 0.232 0.768
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.233 0.767
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.241 0.759
D55-D59 Haemolytic anaemias
0.000 0.241 0.759
D86 Sarcoidosis
0.000 0.243 0.757
E10.3 With ophthalmic complications
0.000 0.244 0.756
H72.0 Central perforation of tympanic membrane
0.000 0.244 0.756
E27.1 Primary adrenocortical insufficiency
0.000 0.245 0.755
B99-B99 Other infectious diseases
0.000 0.245 0.755
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.247 0.753
M00-M03 Infectious arthropathies
0.000 0.250 0.750
E66.0 Obesity due to excess calories
0.000 0.251 0.749
E73 Lactose intolerance
0.000 0.252 0.748
H80 Otosclerosis
0.000 0.253 0.747
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.257 0.743
M35.0 Sicca syndrome [Sjogren]
0.000 0.257 0.743
L30 Other dermatitis
0.000 0.261 0.739
E88 Other metabolic disorders
0.000 0.262 0.738
H65.9 Nonsuppurative otitis media, unspecified
0.000 0.264 0.736
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.265 0.735
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.271 0.729
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.273 0.727
Chapter XXII Codes for special purposes
0.000 0.275 0.725
L27 Dermatitis due to substances taken internally
0.000 0.276 0.724
M34 Systemic sclerosis
0.000 0.277 0.723
B34.8 Other viral infections of unspecified site
0.000 0.279 0.721
E65 Localised adiposity
0.000 0.281 0.719
D68.5 Primary Thrombophilia
0.000 0.282 0.718
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.284 0.716
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.284 0.715
L44 Other papulosquamous disorders
0.000 0.285 0.715
L41 Parapsoriasis
0.000 0.285 0.715
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.285 0.715
L40.8 Other psoriasis
0.000 0.286 0.714
L40.4 Guttate psoriasis
0.000 0.286 0.714
L40.3 Pustulosis palmaris et plantaris
0.000 0.286 0.714
L40.2 Acrodermatitis continua
0.000 0.286 0.714
L40.1 Generalised pustular psoriasis
0.000 0.286 0.714
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.287 0.713
L58 Radiodermatitis
0.000 0.287 0.713
L55 Sunburn
0.000 0.287 0.713
H73 Other disorders of tympanic membrane
0.000 0.288 0.712
E10.1 With ketoacidosis
0.000 0.289 0.711
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.289 0.710
L57.5 Actinic granuloma
0.000 0.289 0.710
L57.3 Poikiloderma of Civatte
0.000 0.289 0.710
L57.2 Cutis rhomboidalis nuchae
0.000 0.289 0.710
L57.1 Actinic reticuloid
0.000 0.289 0.710
D68.9 Coagulation defect, unspecified
0.000 0.290 0.710
E67 Other hyperalimentation
0.000 0.290 0.710
E68 Sequelae of hyperalimentation
0.000 0.290 0.710
L05 Pilonidal cyst
0.000 0.290 0.710
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.290 0.710
M14 Arthropathies in other diseases classified elsewhere
0.000 0.292 0.708
M06.8 Other specified rheumatoid arthritis
0.000 0.292 0.708
M06.2 Rheumatoid bursitis
0.000 0.292 0.708
M06.1 Adult-onset Still's disease
0.000 0.292 0.708
M12 Other specific arthropathies
0.000 0.293 0.707
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.293 0.707
M08 Juvenile arthritis
0.000 0.293 0.707
E66.1 Drug-induced obesity
0.000 0.295 0.705
D50.1 Sideropenic dysphagia
0.000 0.296 0.704
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.296 0.704
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.300 0.700
E50-E64 Other nutritional deficiencies
0.000 0.302 0.698
M35.7 Hypermobility syndrome
0.000 0.307 0.693
H60-H62 Diseases of external ear
0.000 0.309 0.691
D86.9 Sarcoidosis, unspecified
0.000 0.309 0.691
E74 Other disorders of carbohydrate metabolism
0.000 0.311 0.689
B25 Cytomegaloviral disease
0.000 0.312 0.688
E06.9 Thyroiditis, unspecified
0.000 0.312 0.688
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.314 0.686
A75-A79 Rickettsioses
0.000 0.314 0.686
A70-A74 Other diseases caused by chlamydiae
0.000 0.314 0.686
A65-A69 Other spirochaetal diseases
0.000 0.314 0.686
A20-A28 Certain zoonotic bacterial diseases
0.000 0.314 0.686
E14 Unspecified diabetes mellitus
0.000 0.315 0.685
F30-F39 Mood [affective] disorders
0.000 0.315 0.685
L04 Acute lymphadenitis
0.000 0.315 0.685
L01 Impetigo
0.000 0.315 0.685
L00 Staphylococcal scalded skin syndrome
0.000 0.315 0.685
L57.4 Cutis laxa senilis
0.000 0.318 0.681
H80.9 Otosclerosis, unspecified
0.000 0.320 0.680
E84 Cystic fibrosis
0.000 0.320 0.680
E79 Disorders of purine and pyrimidine metabolism
0.000 0.320 0.680
E77 Disorders of glycoprotein metabolism
0.000 0.320 0.680
E76 Disorders of glycosaminoglycan metabolism
0.000 0.320 0.680
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.320 0.680
E72 Other disorders of amino-acid metabolism
0.000 0.320 0.680
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.320 0.680
E70 Disorders of aromatic amino-acid metabolism
0.000 0.320 0.680
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.320 0.680
F40-F48 Neurotic, stress-related and somatoform disorders
0.000 0.322 0.678
B48 Other mycoses, not elsewhere classified
0.000 0.322 0.678
B47 Mycetoma
0.000 0.322 0.678
B46 Zygomycosis
0.000 0.322 0.678
B45 Cryptococcosis
0.000 0.322 0.678
B43 Chromomycosis and phaeomycotic abscess
0.000 0.322 0.678
B42 Sporotrichosis
0.000 0.322 0.678
B41 Paracoccidioidomycosis
0.000 0.322 0.678
B40 Blastomycosis
0.000 0.322 0.678
B39 Histoplasmosis
0.000 0.322 0.678
B38 Coccidioidomycosis
0.000 0.322 0.678
B36 Other superficial mycoses
0.000 0.322 0.678
L10-L14 Bullous disorders
0.000 0.323 0.677
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.000 0.323 0.677
B37.7 Candidal septicaemia
0.000 0.325 0.675
B37.6 Candidal endocarditis
0.000 0.325 0.675
B37.5 Candidal meningitis
0.000 0.325 0.675
B24 Unspecified human immunodeficiency virus [HIV] disease
0.000 0.325 0.675
H83 Other diseases of inner ear
0.000 0.326 0.674
F00-F09 Organic, including symptomatic, mental disorders
0.000 0.326 0.674
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.327 0.673
E10.2 With renal complications
0.000 0.328 0.672
M46 Other inflammatory spondylopathies
0.000 0.328 0.671
E87.2 Acidosis
0.000 0.329 0.671
F80-F89 Disorders of psychological development
0.000 0.329 0.671
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.330 0.670
E10.5 With peripheral circulatory complications
0.000 0.331 0.669
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.332 0.668
A15-A19 Tuberculosis
0.000 0.332 0.668
E40-E46 Malnutrition
0.000 0.332 0.668
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.334 0.666
H68 Eustachian salpingitis and obstruction
0.000 0.334 0.666
H67 Otitis media in diseases classified elsewhere
0.000 0.334 0.666
H65.2 Chronic serous otitis media
0.000 0.335 0.665
L28 Lichen simplex chronicus and prurigo
0.000 0.335 0.665
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.336 0.664
H70 Mastoiditis and related conditions
0.000 0.336 0.664
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.338 0.662
M11 Other crystal arthropathies
0.000 0.338 0.662
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.340 0.660
E03.8 Other specified hypothyroidism
0.000 0.341 0.659
B50-B64 Protozoal diseases
0.000 0.341 0.658
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.342 0.658
L24 Irritant contact dermatitis
0.000 0.343 0.657
L21 Seborrhoeic dermatitis
0.000 0.343 0.657
L26 Exfoliative dermatitis
0.000 0.343 0.657
L22 Diaper [napkin] dermatitis
0.000 0.343 0.657
F60-F69 Disorders of adult personality and behaviour
0.000 0.344 0.656
H72.1 Attic perforation of tympanic membrane
0.000 0.345 0.655
H65.4 Other chronic nonsuppurative otitis media
0.000 0.345 0.655
B33 Other viral diseases, not elsewhere classified
0.000 0.347 0.653
B30 Viral conjunctivitis
0.000 0.347 0.653
B27 Infectious mononucleosis
0.000 0.347 0.653
B26 Mumps
0.000 0.347 0.653
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.348 0.652
E06.5 Other chronic thyroiditis
0.000 0.349 0.651
E06.4 Drug-induced thyroiditis
0.000 0.349 0.651
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.349 0.651
E06.1 Subacute thyroiditis
0.000 0.349 0.651
E06.0 Acute thyroiditis
0.000 0.349 0.651
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.349 0.651
L20 Atopic dermatitis
0.000 0.351 0.649
M07.6 Other enteropathic arthropathies
0.000 0.352 0.648
M07.5 Arthropathy in ulcerative colitis
0.000 0.352 0.648
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.352 0.648
M07.2 Psoriatic spondylitis
0.000 0.352 0.648
M07.1 Arthritis mutilans
0.000 0.352 0.648
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.352 0.648
E10.4 With neurological complications
0.000 0.353 0.647
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.354 0.646
D52 Folate deficiency anaemia
0.000 0.356 0.644
D66 Hereditary factor VIII deficiency
0.000 0.356 0.644
D67 Hereditary factor IX deficiency
0.000 0.357 0.643
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.357 0.643
D86.0 Sarcoidosis of lung
0.000 0.357 0.643
D69 Purpura and other haemorrhagic conditions
0.000 0.359 0.641
M99 Biomechanical lesions, not elsewhere classified
0.000 0.360 0.640
B15-B19 Viral hepatitis
0.000 0.361 0.639
L25 Unspecified contact dermatitis
0.000 0.362 0.638
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.362 0.638
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.362 0.638
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.362 0.638
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.362 0.638
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.362 0.638
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.362 0.638
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.362 0.638
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.362 0.638
E12 Malnutrition-related diabetes mellitus
0.000 0.363 0.637
E22 Hyperfunction of pituitary gland
0.000 0.364 0.636
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.364 0.636
H65.3 Chronic mucoid otitis media
0.000 0.364 0.636
M06.3 Rheumatoid nodule
0.000 0.366 0.634
D51 Vitamin B12 deficiency anaemia
0.000 0.366 0.634
D68.0 Von Willebrand's disease
0.000 0.366 0.634
E85 Amyloidosis
0.000 0.367 0.633
B37.9 Candidiasis, unspecified
0.000 0.368 0.632
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.368 0.632
B35.1 Tinea unguium
0.000 0.368 0.632
M49 Spondylopathies in diseases classified elsewhere
0.000 0.370 0.630
F31 Bipolar affective disorder
0.000 0.373 0.627
E07 Other disorders of thyroid
0.000 0.374 0.626
M91-M94 Chondropathies
0.000 0.374 0.626
B34.3 Parvovirus infection, unspecified
0.000 0.374 0.626
B34.2 Coronavirus infection, unspecified
0.000 0.374 0.626
B34.1 Enterovirus infection, unspecified
0.000 0.374 0.626
B34.0 Adenovirus infection, unspecified
0.000 0.374 0.626
M60-M63 Disorders of muscles
0.000 0.375 0.624
B37.4 Candidiasis of other urogenital sites
0.000 0.376 0.624
B65-B83 Helminthiases
0.000 0.377 0.623
M06.4 Inflammatory polyarthropathy
0.000 0.377 0.623
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.378 0.621
L23 Allergic contact dermatitis
0.000 0.379 0.621
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.380 0.620
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.380 0.620
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.380 0.620
E89.5 Postprocedural testicular hypofunction
0.000 0.380 0.620
E89.4 Postprocedural ovarian failure
0.000 0.380 0.620
E89.1 Postprocedural hypoinsulinaemia
0.000 0.380 0.620
B37.1 Pulmonary candidiasis
0.000 0.381 0.618
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.382 0.618
E10.0 With coma
0.000 0.382 0.618
E10.7 With multiple complications
0.000 0.382 0.618
D59 Acquired haemolytic anaemia
0.000 0.382 0.618
B37.2 Candidiasis of skin and nail
0.000 0.385 0.615
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.386 0.614
M30 Polyarteritis nodosa and related conditions
0.000 0.387 0.613
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.388 0.612
M34.9 Systemic sclerosis, unspecified
0.000 0.389 0.611
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.000 0.389 0.610
M95.8 Other specified acquired deformities of musculoskeletal system
0.000 0.389 0.610
M95.5 Acquired deformity of pelvis
0.000 0.389 0.610
M95.4 Acquired deformity of chest and rib
0.000 0.389 0.610
M95.3 Acquired deformity of neck
0.000 0.389 0.610
M95.2 Other acquired deformity of head
0.000 0.389 0.610
M95.1 Cauliflower ear
0.000 0.389 0.610
E05.5 Thyroid crisis or storm
0.000 0.390 0.610
E05.4 Thyrotoxicosis factitia
0.000 0.390 0.610
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.390 0.610
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.390 0.610
B99 Other and unspecified infectious diseases
0.000 0.390 0.610
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.390 0.610
E05.9 Thyrotoxicosis, unspecified
0.000 0.390 0.610
L05.0 Pilonidal cyst with abscess
0.000 0.392 0.608
E89.3 Postprocedural hypopituitarism
0.000 0.392 0.608
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.393 0.607
M35.8 Other specified systemic involvement of connective tissue
0.000 0.393 0.607
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.393 0.607
M35.5 Multifocal fibrosclerosis
0.000 0.393 0.607
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.393 0.607
M35.2 Behcet's disease
0.000 0.393 0.607
M35.1 Other overlap syndromes
0.000 0.393 0.607
H65.1 Other acute nonsuppurative otitis media
0.000 0.393 0.607
H65.0 Acute serous otitis media
0.000 0.393 0.607
M07.38 Other psoriatic arthropathies (Other)
0.000 0.394 0.606
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.394 0.606
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.394 0.606
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.394 0.606
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.394 0.606
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.394 0.606
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.394 0.606
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.394 0.606
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.395 0.605
M32 Systemic lupus erythematosus
0.000 0.395 0.605
B34.4 Papovirus infection, unspecified
0.000 0.395 0.605
D68.2 Hereditary deficiency of other clotting factors
0.000 0.395 0.605
L30.8 Other specified dermatitis
0.000 0.395 0.605
E73.9 Lactose intolerance, unspecified
0.000 0.395 0.605
E87.7 Fluid overload
0.000 0.396 0.604
H82 Vertiginous syndromes in diseases classified elsewhere
0.000 0.398 0.602
F42 Obsessive-compulsive disorder
0.000 0.398 0.602
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.398 0.602
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.398 0.601
L29.9 Pruritus, unspecified
0.000 0.399 0.601
M22 Disorders of patella
0.000 0.400 0.600
M05.8 Other seropositive rheumatoid arthritis
0.000 0.401 0.599
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.401 0.599
M05.2 Rheumatoid vasculitis
0.000 0.401 0.599
M05.1 Rheumatoid lung disease
0.000 0.401 0.599
M05.0 Felty's syndrome
0.000 0.401 0.599
D53 Other nutritional anaemias
0.000 0.402 0.597
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.404 0.596
D68.4 Acquired coagulation factor deficiency
0.000 0.406 0.593
D68.1 Hereditary factor XI deficiency
0.000 0.406 0.593
D50.8 Other iron deficiency anaemias
0.000 0.407 0.593
E14.9 Without complications
0.000 0.408 0.592
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.409 0.591
D84 Other immunodeficiencies
0.000 0.409 0.590
D83 Common variable immunodeficiency
0.000 0.409 0.590
D82 Immunodeficiency associated with other major defects
0.000 0.409 0.590
D81 Combined immunodeficiencies
0.000 0.409 0.590
L42 Pityriasis rosea
0.000 0.411 0.589
E89.2 Postprocedural hypoparathyroidism
0.000 0.412 0.587
L29.8 Other pruritus
0.000 0.413 0.587
L29.3 Anogenital pruritus, unspecified
0.000 0.413 0.587
L29.1 Pruritus scroti
0.000 0.413 0.587
H69 Other disorders of Eustachian tube
0.000 0.415 0.585
F70-F79 Mental retardation
0.000 0.417 0.583
M00 Pyogenic arthritis
0.000 0.418 0.582
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.421 0.579
E32 Diseases of thymus
0.000 0.421 0.579
E31 Polyglandular dysfunction
0.000 0.421 0.579
E30 Disorders of puberty, not elsewhere classified
0.000 0.421 0.579
E25 Adrenogenital disorders
0.000 0.421 0.579
E20 Hypoparathyroidism
0.000 0.421 0.579
E10.8 With unspecified complications
0.000 0.421 0.579
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.427 0.573
E87.4 Mixed disorder of acid-base balance
0.000 0.428 0.572
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.428 0.572
E83 Disorders of mineral metabolism
0.000 0.429 0.571
F81 Specific developmental disorders of scholastic skills
0.000 0.430 0.570
H72.2 Other marginal perforations of tympanic membrane
0.000 0.431 0.569
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.431 0.569
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.431 0.569
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.431 0.569
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.431 0.569
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.431 0.569
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.431 0.569
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.431 0.569
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.000 0.431 0.569
F43 Reaction to severe stress, and adjustment disorders
0.000 0.431 0.569
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions
0.000 0.431 0.568
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases
0.000 0.431 0.568
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms
0.000 0.431 0.568
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
0.000 0.431 0.568
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.432 0.568
L40.0 Psoriasis vulgaris
0.000 0.432 0.568
D60-D64 Aplastic and other anaemias
0.000 0.436 0.564
B35.3 Tinea pedis
0.000 0.436 0.564
M34.1 CR(E)ST syndrome
0.000 0.436 0.564
L43 Lichen planus
0.000 0.437 0.563
L08.1 Erythrasma
0.000 0.437 0.563
L08.0 Pyoderma
0.000 0.437 0.563
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.437 0.563
M31 Other necrotising vasculopathies
0.000 0.437 0.563
M33 Dermatopolymyositis
0.000 0.437 0.563
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.000 0.439 0.561
D68.6 Other Thrombophilia
0.000 0.440 0.560
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.441 0.559
H72.8 Other perforations of tympanic membrane
0.000 0.441 0.558
E27.5 Adrenomedullary hyperfunction
0.000 0.443 0.557
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.443 0.557
E27.2 Addisonian crisis
0.000 0.443 0.557
E27.0 Other adrenocortical overactivity
0.000 0.443 0.557
H73.8 Other specified disorders of tympanic membrane
0.000 0.443 0.557
E26 Hyperaldosteronism
0.000 0.444 0.556
H83.0 Labyrinthitis
0.000 0.444 0.556
E10.6 With other specified complications
0.000 0.445 0.555
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.446 0.554
M10 Gout
0.000 0.449 0.551
L50-L54 Urticaria and erythema
0.000 0.449 0.551
B37.3 Candidiasis of vulva and vagina
0.000 0.449 0.551
B35.9 Dermatophytosis, unspecified
0.000 0.449 0.550
B35.8 Other dermatophytoses
0.000 0.449 0.550
B35.6 Tinea cruris
0.000 0.449 0.550
B35.5 Tinea imbricata
0.000 0.449 0.550
B35.4 Tinea corporis
0.000 0.449 0.550
B35.2 Tinea manuum
0.000 0.449 0.550
B35.0 Tinea barbae and tinea capitis
0.000 0.449 0.550
F20 Schizophrenia
0.000 0.450 0.550
F42.9 Obsessive-compulsive disorder, unspecified
0.000 0.453 0.547
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.453 0.547
M13 Other arthritis
0.000 0.454 0.546
F99-F99 Unspecified mental disorder
0.000 0.455 0.545
M80-M85 Disorders of bone density and structure
0.001 0.455 0.544
D57 Sickle-cell disorders
0.000 0.456 0.544
D56 Thalassaemia
0.000 0.456 0.544
D55 Anaemia due to enzyme disorders
0.000 0.456 0.544
F30 Manic episode
0.000 0.456 0.544
D86.3 Sarcoidosis of skin
0.000 0.457 0.543
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.457 0.543
D86.1 Sarcoidosis of lymph nodes
0.000 0.457 0.543
L30.9 Dermatitis, unspecified
0.000 0.457 0.543
A80-A89 Viral infections of the central nervous system
0.000 0.458 0.542
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.458 0.542
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.461 0.539
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.000 0.462 0.538
M02 Reactive arthropathies
0.000 0.462 0.538
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.000 0.462 0.538
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.463 0.537
E73.8 Other lactose intolerance
0.000 0.463 0.536
E73.1 Secondary lactase deficiency
0.000 0.463 0.536
E73.0 Congenital lactase deficiency
0.000 0.463 0.536
H80.8 Other otosclerosis
0.000 0.464 0.536
H80.2 Cochlear otosclerosis
0.000 0.464 0.536
H80.1 Otosclerosis involving oval window, obliterative
0.000 0.464 0.536
H80.0 Otosclerosis involving oval window, nonobliterative
0.000 0.464 0.536
B49 Unspecified mycosis
0.000 0.465 0.535
F40 Phobic anxiety disorders
0.000 0.465 0.535
E34 Other endocrine disorders
0.000 0.467 0.533
E13 Other specified diabetes mellitus
0.000 0.467 0.533
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.467 0.533
L56.4 Polymorphous light eruption
0.000 0.467 0.533
L56.3 Solar urticaria
0.000 0.467 0.533
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.467 0.533
L56.1 Drug photoallergic response
0.000 0.467 0.533
L56.0 Drug phototoxic response
0.000 0.467 0.533
F22 Persistent delusional disorders
0.000 0.468 0.532
L30.5 Pityriasis alba
0.000 0.470 0.530
L30.4 Erythema intertrigo
0.000 0.470 0.530
L30.3 Infective dermatitis
0.000 0.470 0.530
L30.2 Cutaneous autosensitisation
0.000 0.470 0.530
L30.1 Dyshidrosis [pompholyx]
0.000 0.470 0.530
L30.0 Nummular dermatitis
0.000 0.470 0.530
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.470 0.529
E88.9 Metabolic disorder, unspecified
0.000 0.471 0.529
E88.8 Other specified metabolic disorders
0.000 0.471 0.529
E88.3 Tumour lysis syndrome
0.000 0.471 0.529
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.471 0.529
F60 Specific personality disorders
0.000 0.471 0.529
E80.4 Gilbert's syndrome
0.000 0.471 0.529
F05 Delirium, not induced by alcohol and other psychoactive substances
0.000 0.471 0.529
E53 Deficiency of other B group vitamins
0.000 0.472 0.528
H81 Disorders of vestibular function
0.000 0.472 0.528
B25.9 Cytomegaloviral disease, unspecified
0.000 0.472 0.528
A59 Trichomoniasis
0.000 0.473 0.527

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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