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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857596
log Bayes Factor = 47.5794
Chromosome 6   position 31,567,422  (GRCh37) Explore rs2857596 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.001 0.999
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.003 0.997
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.004 0.996
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.006 0.994
E10.1 With ketoacidosis
0.000 0.006 0.994
E70-E90 Metabolic disorders
0.000 0.011 0.989
E05.9 Thyrotoxicosis, unspecified
0.000 0.013 0.987
K90.0 Coeliac disease
0.000 0.018 0.982
E10.4 With neurological complications
0.000 0.022 0.978
E83.1 Disorders of iron metabolism
0.972 0.028 0.000
E14 Unspecified diabetes mellitus
0.000 0.031 0.969
E11 Non-insulin-dependent diabetes mellitus
0.000 0.048 0.952
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.049 0.951
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.056 0.944
G35-G37 Demyelinating diseases of the central nervous system
0.941 0.059 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.062 0.938
E06 Thyroiditis
0.000 0.066 0.934
G37 Other demyelinating diseases of central nervous system
0.929 0.071 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.908 0.092 0.000
E10.2 With renal complications
0.000 0.094 0.906
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.096 0.904
E11.1 With ketoacidosis
0.000 0.099 0.901
L40.5 Arthropathic psoriasis
0.000 0.099 0.901
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.101 0.899
E06.3 Autoimmune thyroiditis
0.000 0.106 0.894
L40 Psoriasis
0.000 0.111 0.889
E78.8 Other disorders of lipoprotein metabolism
0.000 0.115 0.885
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.116 0.884
L40.9 Psoriasis, unspecified
0.000 0.123 0.877
E11.9 Without complications
0.000 0.124 0.876
E14.3 With ophthalmic complications
0.000 0.124 0.876
I10 Essential (primary) hypertension
0.000 0.146 0.854
E14.9 Without complications
0.000 0.146 0.854
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.154 0.846
M45 Ankylosing spondylitis
0.000 0.159 0.841
M06 Other rheumatoid arthritis
0.000 0.161 0.839
E78.2 Mixed hyperlipidaemia
0.000 0.175 0.825
E10.8 With unspecified complications
0.000 0.186 0.814
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.188 0.812
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.195 0.805
E14.4 With neurological complications
0.000 0.200 0.800
E10.0 With coma
0.000 0.210 0.790
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.215 0.785
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.781 0.219 0.000
E11.3 With ophthalmic complications
0.000 0.221 0.779
E78.1 Pure hyperglyceridaemia
0.000 0.222 0.778
E10.6 With other specified complications
0.000 0.225 0.775
I10-I15 Hypertensive diseases
0.000 0.228 0.772
E10.5 With peripheral circulatory complications
0.000 0.233 0.767
E14.8 With unspecified complications
0.000 0.238 0.762
E74 Other disorders of carbohydrate metabolism
0.000 0.240 0.760
E07 Other disorders of thyroid
0.000 0.241 0.759
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.244 0.756
E11.0 With coma
0.000 0.251 0.749
I12 Hypertensive renal disease
0.000 0.252 0.748
E78.4 Other hyperlipidaemia
0.000 0.255 0.745
E11.2 With renal complications
0.000 0.256 0.744
L40.8 Other psoriasis
0.000 0.256 0.744
E14.1 With ketoacidosis
0.000 0.261 0.739
I12.9 Hypertensive renal disease without renal failure
0.000 0.261 0.739
G37.8 Other specified demyelinating diseases of central nervous system
0.729 0.271 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.280 0.720
E40-E46 Malnutrition
0.000 0.280 0.720
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.286 0.714
E05.4 Thyrotoxicosis factitia
0.000 0.286 0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.286 0.714
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.286 0.714
E78.3 Hyperchylomicronaemia
0.000 0.287 0.713
E77 Disorders of glycoprotein metabolism
0.000 0.291 0.709
E76 Disorders of glycosaminoglycan metabolism
0.000 0.291 0.709
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.291 0.709
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.291 0.709
L40.1 Generalised pustular psoriasis
0.000 0.299 0.701
E70 Disorders of aromatic amino-acid metabolism
0.000 0.299 0.701
E78.6 Lipoprotein deficiency
0.000 0.300 0.700
E14.7 With multiple complications
0.000 0.305 0.695
E14.5 With peripheral circulatory complications
0.000 0.305 0.695
E14.0 With coma
0.000 0.305 0.695
M06.0 Seronegative rheumatoid arthritis
0.000 0.307 0.693
E11.7 With multiple complications
0.000 0.318 0.682
E79 Disorders of purine and pyrimidine metabolism
0.000 0.320 0.680
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.321 0.679
G36 Other acute disseminated demyelination
0.675 0.325 0.000
E06.5 Other chronic thyroiditis
0.000 0.330 0.670
E06.4 Drug-induced thyroiditis
0.000 0.330 0.670
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.330 0.670
E06.1 Subacute thyroiditis
0.000 0.330 0.670
E06.0 Acute thyroiditis
0.000 0.330 0.670
E73 Lactose intolerance
0.000 0.331 0.669
E11.5 With peripheral circulatory complications
0.000 0.332 0.668
G37.5 Concentric sclerosis [Balo]
0.666 0.334 0.000
G37.4 Subacute necrotising myelitis
0.666 0.334 0.000
G37.2 Central pontine myelinolysis
0.666 0.334 0.000
G37.1 Central demyelination of corpus callosum
0.666 0.334 0.000
G37.0 Diffuse sclerosis
0.666 0.334 0.000
M05-M14 Inflammatory polyarthropathies
0.000 0.335 0.665
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.335 0.665
E89.0 Postprocedural hypothyroidism
0.000 0.336 0.664
M07 Psoriatic and enteropathic arthropathies
0.000 0.339 0.661
E72 Other disorders of amino-acid metabolism
0.000 0.340 0.660
M07.3 Other psoriatic arthropathies
0.000 0.341 0.659
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.342 0.658
E14.6 With other specified complications
0.000 0.343 0.657
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.344 0.656
E84 Cystic fibrosis
0.000 0.348 0.652
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.352 0.648
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.357 0.643
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.357 0.643
M06.3 Rheumatoid nodule
0.000 0.358 0.642
L40.4 Guttate psoriasis
0.000 0.363 0.637
L40.2 Acrodermatitis continua
0.000 0.363 0.637
E14.2 Withrenal complications
0.000 0.372 0.628
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.373 0.627
E06.9 Thyroiditis, unspecified
0.000 0.373 0.626
E07.8 Other specified disorders of thyroid
0.000 0.376 0.624
E11.6 With other specified complications
0.000 0.377 0.623
E20-E35 Disorders of other endocrine glands
0.000 0.379 0.621
E88 Other metabolic disorders
0.000 0.382 0.618
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.385 0.615
E89.3 Postprocedural hypopituitarism
0.000 0.387 0.613
L40-L45 Papulosquamous disorders
0.000 0.389 0.611
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.393 0.607
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.395 0.605
I15 Secondary hypertension
0.000 0.395 0.605
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.397 0.603
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.397 0.603
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.397 0.603
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.397 0.603
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.397 0.603
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.397 0.603
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.397 0.603
M06.8 Other specified rheumatoid arthritis
0.000 0.398 0.601
M06.2 Rheumatoid bursitis
0.000 0.398 0.601
M06.1 Adult-onset Still's disease
0.000 0.398 0.601
L40.3 Pustulosis palmaris et plantaris
0.000 0.401 0.599
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.404 0.596
E13 Other specified diabetes mellitus
0.000 0.414 0.586
E03.8 Other specified hypothyroidism
0.000 0.418 0.582
E03.1 Congenital hypothyroidism without goitre
0.000 0.419 0.580
E50-E64 Other nutritional deficiencies
0.001 0.420 0.579
E05.8 Other thyrotoxicosis
0.000 0.434 0.566
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.437 0.563
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.437 0.563
E89.5 Postprocedural testicular hypofunction
0.000 0.437 0.563
E89.1 Postprocedural hypoinsulinaemia
0.000 0.437 0.563
E89.4 Postprocedural ovarian failure
0.000 0.449 0.551
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.455 0.545
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.455 0.545
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.455 0.545
E74.2 Disorders of galactose metabolism
0.000 0.455 0.545
E74.1 Disorders of fructose metabolism
0.000 0.455 0.545
E74.0 Glycogen storage disease
0.000 0.455 0.545
E07.1 Dyshormogenetic goitre
0.000 0.455 0.544
E07.0 Hypersecretion of calcitonin
0.000 0.455 0.544
L40.0 Psoriasis vulgaris
0.000 0.459 0.541
E28 Ovarian dysfunction
0.000 0.459 0.541
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.465 0.535
L43 Lichen planus
0.000 0.467 0.533
I13 Hypertensive heart and renal disease
0.000 0.470 0.530
M06.4 Inflammatory polyarthropathy
0.000 0.471 0.528
I11 Hypertensive heart disease
0.000 0.476 0.524
M06.34 Rheumatoid nodule (Hand)
0.000 0.479 0.521
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.481 0.519
E46 Unspecified protein-energy malnutrition
0.000 0.481 0.519
E23 Hypofunction and other disorders of pituitary gland
0.000 0.483 0.517
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.484 0.516
E45 Retarded development following protein-energy malnutrition
0.000 0.484 0.516
E43 Unspecified severe protein-energy malnutrition
0.000 0.484 0.516
E42 Marasmic kwashiorkor
0.000 0.484 0.516
E41 Nutritional marasmus
0.000 0.484 0.516
E40 Kwashiorkor
0.000 0.484 0.516
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E61 Deficiency of other nutrient elements
0.000 0.489 0.511
E71.3 Disorders of fatty-acid metabolism
0.000 0.491 0.508
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.491 0.508
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.491 0.508
E71.0 Maple-syrup-urine disease
0.000 0.491 0.508
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.491 0.508
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.491 0.508
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.491 0.508
E76.2 Other mucopolysaccharidoses
0.000 0.491 0.508
E76.1 Mucopolysaccharidosis, type II
0.000 0.491 0.508
E76.0 Mucopolysaccharidosis, type I
0.000 0.491 0.508
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.491 0.508
E77.8 Other disorders of glycoprotein metabolism
0.000 0.491 0.508
E77.1 Defects in glycoprotein degradation
0.000 0.491 0.508
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.491 0.508
E11.8 With unspecified complications
0.000 0.496 0.504
E85 Amyloidosis
0.000 0.496 0.503
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.497 0.502
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.497 0.502
E70.2 Disorders of tyrosine metabolism
0.000 0.497 0.502
E70.1 Other hyperphenylalaninaemias
0.000 0.497 0.502
E70.0 Classical phenylketonuria
0.000 0.497 0.502
E88.2 Lipomatosis, not elsewhere classified
0.000 0.498 0.502
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.503 0.497
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.503 0.497
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.503 0.497
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.503 0.497
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.503 0.497
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.503 0.497
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.503 0.497
E70.3 Albinism
0.000 0.506 0.494
E22 Hyperfunction of pituitary gland
0.000 0.510 0.490
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.511 0.489
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.512 0.488
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.512 0.488
E79.1 Lesch-Nyhan syndrome
0.000 0.512 0.488
E75.6 Lipid storage disorder, unspecified
0.000 0.513 0.487
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.513 0.487
E75.3 Sphingolipidosis, unspecified
0.000 0.513 0.487
E75.2 Other sphingolipidosis
0.000 0.513 0.487
E75.1 Other gangliosidosis
0.000 0.513 0.487
E75.0 GM2 gangliosidosis
0.000 0.513 0.487
E07.9 Disorder of thyroid, unspecified
0.000 0.514 0.486
E80.6 Other disorders of bilirubin metabolism
0.000 0.514 0.485
G36.9 Acute disseminated demyelination, unspecified
0.484 0.516 0.000
G36.8 Other specified acute disseminated demyelination
0.484 0.516 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.484 0.516 0.000
G36.0 Neuromyelitis optica [Devic]
0.484 0.516 0.000
M11 Other crystal arthropathies
0.000 0.519 0.481
E73.8 Other lactose intolerance
0.000 0.520 0.480
E73.1 Secondary lactase deficiency
0.000 0.520 0.480
E73.0 Congenital lactase deficiency
0.000 0.520 0.480
E88.8 Other specified metabolic disorders
0.000 0.521 0.479
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.523 0.477
E83 Disorders of mineral metabolism
0.358 0.525 0.117
M07.6 Other enteropathic arthropathies
0.000 0.526 0.474
M07.5 Arthropathy in ulcerative colitis
0.000 0.526 0.474
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.526 0.474
M07.2 Psoriatic spondylitis
0.000 0.526 0.474
M07.1 Arthritis mutilans
0.000 0.526 0.474
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.526 0.474
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.527 0.473
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.527 0.473
E72.5 Disorders of glycine metabolism
0.000 0.527 0.473
E72.4 Disorders of ornithine metabolism
0.000 0.527 0.473
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.527 0.473
E72.2 Disorders of urea cycle metabolism
0.000 0.527 0.473
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.527 0.473
M07.38 Other psoriatic arthropathies (Other)
0.000 0.527 0.472
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.527 0.472
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.527 0.472
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.527 0.472
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.527 0.472
E26 Hyperaldosteronism
0.000 0.528 0.472
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.528 0.472
E61.1 Iron deficiency
0.000 0.529 0.470
E15 Nondiabetic hypoglycaemic coma
0.000 0.530 0.470
I15.1 Hypertension secondary to other renal disorders
0.000 0.531 0.469
E65-E68 Obesity and other hyperalimentation
0.000 0.531 0.469
E24 Cushing's syndrome
0.000 0.532 0.468
E84.8 Cystic fibrosis with other manifestations
0.000 0.532 0.467
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.532 0.467
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.532 0.467
E28.2 Polycystic ovarian syndrome
0.000 0.533 0.467
L43.9 Lichen planus, unspecified
0.000 0.533 0.467
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.537 0.463
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.538 0.462
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.539 0.461
M06.38 Rheumatoid nodule (Other)
0.000 0.539 0.461
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.539 0.461
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.539 0.461
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.539 0.461
E29 Testicular dysfunction
0.000 0.541 0.459
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.541 0.459
M08 Juvenile arthritis
0.000 0.542 0.458
E75.5 Other lipid storage disorders
0.000 0.543 0.457
I15.9 Seconday hypertension, unspecified
0.000 0.547 0.453
E80.1 Porphyria cutanea tarda
0.000 0.548 0.452
E80.2 Other porphyria
0.000 0.549 0.451
M14 Arthropathies in other diseases classified elsewhere
0.000 0.550 0.449
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.550 0.449
E80.5 Crigler-Najjar syndrome
0.000 0.550 0.449
E80.3 Defects of catalase and peroxydase
0.000 0.550 0.449
E80.0 Hereditary erythropoietic porphyria
0.000 0.550 0.449
E23.7 Disorder of pituitary gland, unspecified
0.000 0.552 0.448
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.554 0.445
E32 Diseases of thymus
0.000 0.554 0.445
E31 Polyglandular dysfunction
0.000 0.554 0.445
E30 Disorders of puberty, not elsewhere classified
0.000 0.554 0.445
E25 Adrenogenital disorders
0.000 0.555 0.445
E73.9 Lactose intolerance, unspecified
0.000 0.560 0.440
L44 Other papulosquamous disorders
0.000 0.562 0.438
L41 Parapsoriasis
0.000 0.562 0.438
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.562 0.438
E23.6 Other disorders of pituitary gland
0.000 0.563 0.437
I15.8 Other secondary hypertension
0.000 0.566 0.433
I15.2 Hypertension secondary to endocrine disorders
0.000 0.566 0.433
I15.0 Renovascular hypertension
0.000 0.566 0.433
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.567 0.433
M12 Other specific arthropathies
0.000 0.567 0.433
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.569 0.431
M06.18 Adult-onset Still's disease (Other)
0.000 0.569 0.431
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.569 0.431
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.569 0.431
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.569 0.431
M06.14 Adult-onset Still's disease (Hand)
0.000 0.569 0.431
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.569 0.431
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.569 0.431
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.569 0.431
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.569 0.431
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.569 0.431
M06.28 Rheumatoid bursitis (Other)
0.000 0.569 0.431
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.569 0.431
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.569 0.431
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.569 0.431
M06.24 Rheumatoid bursitis (Hand)
0.000 0.569 0.431
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.569 0.431
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.569 0.431
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.569 0.431
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.569 0.431
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.569 0.431
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.569 0.431
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.569 0.431
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.569 0.431
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.569 0.431
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.569 0.431
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.569 0.431
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.569 0.431
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.569 0.431
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.569 0.431
E72.0 Disorders of amino-acid transport
0.000 0.576 0.424
M05 Seropositive rheumatoid arthritis
0.000 0.576 0.424
E88.3 Tumour lysis syndrome
0.000 0.577 0.423
L42 Pityriasis rosea
0.000 0.578 0.422
K90 Intestinal malabsorption
0.000 0.578 0.422
E13.8 With unspecified complications
0.000 0.580 0.420
E13.7 With multiple complications
0.000 0.580 0.420
E13.6 With other specified complications
0.000 0.580 0.420
E13.5 With peripheral circulatory complications
0.000 0.580 0.420
E13.4 With neurological complications
0.000 0.580 0.420
E13.2 With renal complications
0.000 0.580 0.420
E13.1 With ketoacidosis
0.000 0.580 0.420
E13.0 With coma
0.000 0.580 0.420
E28.3 Primary ovarian failure
0.000 0.580 0.420
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.584 0.415
E63 Other nutritional deficiencies
0.001 0.584 0.415
E56 Other vitamin deficiencies
0.001 0.584 0.415
E51 Thiamine deficiency
0.001 0.584 0.415
E50 Vitamin A deficiency
0.001 0.584 0.415
E60 Dietary zinc deficiency
0.001 0.584 0.415
E59 Dietary selenium deficiency
0.001 0.584 0.415
E54 Ascorbic acid deficiency
0.001 0.584 0.415
E52 Niacin deficiency [pellagra]
0.001 0.584 0.415
E84.9 Cystic fibrosis, unspecified
0.000 0.590 0.410
E16 Other disorders of pancreatic internal secretion
0.000 0.591 0.409
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.591 0.409
E20 Hypoparathyroidism
0.000 0.592 0.408
E58 Dietary calcium deficiency
0.001 0.592 0.408
L43.8 Other lichen planus
0.000 0.594 0.406
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.596 0.404
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.601 0.399
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.602 0.398
E88.9 Metabolic disorder, unspecified
0.000 0.603 0.397
E13.3 With ophthalmic complications
0.000 0.605 0.395
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.607 0.393
E22.0 Acromegaly and pituitary gigantism
0.000 0.608 0.392
E28.9 Ovarian dysfunction, unspecified
0.000 0.612 0.388
E28.8 Other ovarian dysfunction
0.000 0.612 0.388
E28.1 Androgen excess
0.000 0.612 0.388
E28.0 Oestrogen excess
0.000 0.612 0.388
L43.3 Subacute (active) lichen planus
0.000 0.618 0.382
L43.2 Lichenoid drug reaction
0.000 0.618 0.382
L43.1 Bullous lichen planus
0.000 0.618 0.382
L43.0 Hypertrophic lichen planus
0.000 0.618 0.382
E24.2 Drug-induced Cushing's syndrome
0.000 0.619 0.381
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.620 0.380
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.620 0.380
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.620 0.380
I12.0 Hypertensive renal disease with renal failure
0.000 0.620 0.380
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.621 0.379
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.621 0.379
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.621 0.379
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.621 0.379
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.621 0.379
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.621 0.379
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.621 0.379
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.621 0.379
M06.33 Rheumatoid nodule (Forearm)
0.000 0.626 0.374
M11.2 Other chondrocalcinosis
0.000 0.626 0.374
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.629 0.371
E23.1 Drug-induced hypopituitarism
0.000 0.629 0.371
E44.1 Mild protein-energy malnutrition
0.000 0.630 0.370
E44.0 Moderate protein-energy malnutrition
0.000 0.630 0.370
E85.9 Amyloidosis, unspecified
0.000 0.630 0.370
E23.2 Diabetes insipidus
0.000 0.631 0.369
E61.9 Deficiency of nutrient element, unspecified
0.000 0.633 0.366
E61.8 Deficiency of other specified nutrient elements
0.000 0.633 0.366
E61.7 Deficiency of multiple nutrient elements
0.000 0.633 0.366
E61.6 Vanadium deficiency
0.000 0.633 0.366
E61.5 Molybdenum deficiency
0.000 0.633 0.366
E61.4 Chromium deficiency
0.000 0.633 0.366
E61.3 Manganese deficiency
0.000 0.633 0.366
E61.0 Copper deficiency
0.000 0.633 0.366
E26.0 Primary hyperaldosteronism
0.000 0.634 0.365
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.639 0.361
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.639 0.361
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.639 0.361
E89.2 Postprocedural hypoparathyroidism
0.000 0.640 0.359
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.643 0.357
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.648 0.352
E22.8 Other hyperfunction of pituitary gland
0.000 0.648 0.352
M14.6 Neuropathic arthropathy
0.000 0.651 0.348
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.654 0.346
M11.1 Familial chondrocalcinosis
0.000 0.655 0.345
M11.0 Hydroxyapatite deposition disease
0.000 0.655 0.345
E29.1 Testicular hypofunction
0.000 0.657 0.343
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.658 0.342
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.658 0.342
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.658 0.342
M09.0 Juvenile arthritis in psoriasis
0.000 0.658 0.342
E83.9 Disorder of mineral metabolism, unspecified
0.257 0.659 0.084
E83.8 Other disorders of mineral metabolism
0.257 0.659 0.084
E83.2 Disorders of zinc metabolism
0.257 0.659 0.084
E83.0 Disorders of copper metabolism
0.257 0.659 0.084
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.000 0.660 0.340
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.000 0.660 0.340
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.000 0.660 0.340
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.000 0.660 0.340
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.000 0.660 0.340
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.000 0.660 0.340
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.000 0.660 0.340
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.000 0.660 0.340
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.000 0.660 0.340
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.000 0.660 0.340
M07.19 Arthritis mutilans (Site unspecified)
0.000 0.660 0.340
M07.18 Arthritis mutilans (Other)
0.000 0.660 0.340
M07.17 Arthritis mutilans (Ankle and foot)
0.000 0.660 0.340
M07.16 Arthritis mutilans (Lower leg)
0.000 0.660 0.340
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.000 0.660 0.340
M07.14 Arthritis mutilans (Hand)
0.000 0.660 0.340
M07.13 Arthritis mutilans (Forearm)
0.000 0.660 0.340
M07.12 Arthritis mutilans (Upper arm)
0.000 0.660 0.340
M07.11 Arthritis mutilans (Shoulder region)
0.000 0.660 0.340
M07.10 Arthritis mutilans (Multiple sites)
0.000 0.660 0.340
M07.29 Psoriatic spondylitis (Site unspecified)
0.000 0.660 0.340
M07.28 Psoriatic spondylitis (Other)
0.000 0.660 0.340
M07.27 Psoriatic spondylitis (Ankle and foot)
0.000 0.660 0.340
M07.26 Psoriatic spondylitis (Lower leg)
0.000 0.660 0.340
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.000 0.660 0.340
M07.24 Psoriatic spondylitis (Hand)
0.000 0.660 0.340
M07.23 Psoriatic spondylitis (Forearm)
0.000 0.660 0.340
M07.22 Psoriatic spondylitis (Upper arm)
0.000 0.660 0.340
M07.21 Psoriatic spondylitis (Shoulder region)
0.000 0.660 0.340
M07.20 Psoriatic spondylitis (Multiple sites)
0.000 0.660 0.340
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.000 0.660 0.340
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.000 0.660 0.340
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.000 0.660 0.340
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.000 0.660 0.340
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.000 0.660 0.340
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.000 0.660 0.340
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.000 0.660 0.340
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.000 0.660 0.340
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.000 0.660 0.340
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.000 0.660 0.340
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.000 0.660 0.340
M07.58 Arthropathy in ulcerative colitis (Other)
0.000 0.660 0.340
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.000 0.660 0.340
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.000 0.660 0.340
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.000 0.660 0.340
M07.54 Arthropathy in ulcerative colitis (Hand)
0.000 0.660 0.340
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.000 0.660 0.340

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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