TreeWAS – Variant ID: rs2858324

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
J45.9 Asthma, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
G35 Multiple sclerosis	1.000	0.000	0.000
M06 Other rheumatoid arthritis	0.000	0.000	1.000
R31 Unspecified haematuria	0.000	0.000	1.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.000	1.000
D80-D89 Certain disorders involving the immune mechanism	1.000	0.000	0.000
D86 Sarcoidosis	1.000	0.000	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	1.000	0.000	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.000	1.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.000	1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
D86.9 Sarcoidosis, unspecified	0.999	0.001	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.001	0.999
J33.9 Nasal polyp, unspecified	0.000	0.002	0.998
L40.9 Psoriasis, unspecified	0.000	0.002	0.998
M06.3 Rheumatoid nodule	0.000	0.002	0.998
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.002	0.998
M05-M14 Inflammatory polyarthropathies	0.000	0.002	0.998
D68 Other coagulation defects	0.997	0.003	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.003	0.997
N48 Other disorders of penis	0.000	0.005	0.995
D69 Purpura and other haemorrhagic conditions	0.993	0.007	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.009	0.991
N48.6 Balanitis xerotica obliterans	0.000	0.014	0.986
K90 Intestinal malabsorption	0.986	0.014	0.000
J33 Nasal polyp	0.000	0.019	0.981
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.019	0.981
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.020	0.980
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.980	0.020	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.978	0.022	0.000
E05.9 Thyrotoxicosis, unspecified	0.976	0.024	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.026	0.974
J33.0 Polyp of nasal cavity	0.000	0.029	0.971
N48.0 Leukoplakia of penis	0.000	0.032	0.968
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.035	0.965
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.036	0.964
K90.9 Intestinal malabsorption, unspecified	0.963	0.037	0.000
D69.6 Thrombocytopenia, unspecified	0.960	0.040	0.000
N40-N51 Diseases of male genital organs	0.000	0.043	0.957
D50-D53 Nutritional anaemias	0.956	0.044	0.000
D68.5 Primary Thrombophilia	0.953	0.047	0.000
D86.0 Sarcoidosis of lung	0.941	0.059	0.000
N48.2 Other inflammatory disorders of penis	0.000	0.064	0.936
D68.8 Other specified coagulation defects	0.935	0.065	0.000
E78.0 Pure hypercholesterolaemia	0.000	0.065	0.935
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.933	0.067	0.000
N48.1 Balanoposthitis	0.000	0.068	0.932
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.071	0.929
D89.2 Hypergammaglobulinaemia, unspecified	0.922	0.078	0.000
D52 Folate deficiency anaemia	0.919	0.081	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.083	0.917
D69.4 Other primary thrombocytopenia	0.915	0.085	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.087	0.913
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.097	0.903
C82.0 Small cleaved cell, follicular	0.000	0.100	0.900
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.899	0.101	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.101	0.899
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.102	0.898
D69.3 Idiopathic thrombocytopenic purpura	0.896	0.104	0.000
D52.9 Folate deficiency anaemia, unspecified	0.892	0.108	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.111	0.889
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.121	0.879
L40 Psoriasis	0.000	0.131	0.869
N48.5 Ulcer of penis	0.000	0.131	0.869
D89.9 Disorder involving the immune mechanism, unspecified	0.859	0.141	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.858	0.142	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.143	0.857
N48.9 Disorder of penis, unspecified	0.000	0.143	0.857
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.145	0.855
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.145	0.855
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.155	0.845
D89.0 Polyclonal hypergammaglobulinaemia	0.841	0.159	0.000
M07 Psoriatic and enteropathic arthropathies	0.000	0.163	0.837
N48.8 Other specified disorders of penis	0.000	0.164	0.836
C82.3 Follicular lymphoma grade IIIa	0.000	0.167	0.833
D68.6 Other Thrombophilia	0.823	0.176	0.000
C82.2 Large cell, follicular	0.000	0.178	0.822
D69.8 Other specified haemorrhagic conditions	0.821	0.179	0.000
L40.5 Arthropathic psoriasis	0.000	0.183	0.816
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.184	0.816
J33.8 Other polyp of sinus	0.000	0.191	0.809
D51 Vitamin B12 deficiency anaemia	0.807	0.193	0.000
D68.0 Von Willebrand's disease	0.806	0.194	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.208	0.792
C34 Malignant neoplasm of bronchus and lung	0.792	0.208	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.210	0.790
C34.9 Bronchus or lung, unspecified	0.790	0.210	0.000
M45 Ankylosing spondylitis	0.000	0.216	0.784
D86.3 Sarcoidosis of skin	0.784	0.216	0.000
D86.1 Sarcoidosis of lymph nodes	0.783	0.217	0.000
D68.9 Coagulation defect, unspecified	0.783	0.217	0.000
K90.8 Other intestinal malabsorption	0.782	0.218	0.000
C34.3 Lower lobe, bronchus or lung	0.779	0.221	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.230	0.770
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.233	0.767
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.235	0.765
C82.4 Follicular lymphoma grade IIIb	0.000	0.244	0.756
N48.4 Impotence of organic origin	0.000	0.245	0.755
D55-D59 Haemolytic anaemias	0.755	0.245	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.254	0.746
N49.2 Inflammatory disorders of scrotum	0.000	0.255	0.745
D82 Immunodeficiency associated with other major defects	0.741	0.258	0.000
M07.3 Other psoriatic arthropathies	0.000	0.259	0.741
D67 Hereditary factor IX deficiency	0.739	0.261	0.000
N44 Torsion of testis	0.000	0.266	0.734
J33.1 Polypoid sinus degeneration	0.000	0.266	0.734
M05.2 Rheumatoid vasculitis	0.000	0.270	0.730
M14 Arthropathies in other diseases classified elsewhere	0.000	0.271	0.728
N51 Disorders of male genital organs in diseases classified elsewhere	0.000	0.272	0.728
D69.5 Secondary thrombocytopenia	0.727	0.272	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.727	0.273	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.273	0.726
D68.4 Acquired coagulation factor deficiency	0.723	0.277	0.000
D89.1 Cryoglobulinaemia	0.719	0.281	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.283	0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.283	0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.283	0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.283	0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.283	0.717
M06.2 Rheumatoid bursitis	0.000	0.283	0.717
D81 Combined immunodeficiencies	0.717	0.283	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.284	0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.284	0.716
M05.1 Rheumatoid lung disease	0.000	0.284	0.716
M05.0 Felty's syndrome	0.000	0.284	0.716
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.284	0.716
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.284	0.716
M06.38 Rheumatoid nodule (Other)	0.000	0.284	0.716
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.284	0.716
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.284	0.716
M06.33 Rheumatoid nodule (Forearm)	0.000	0.284	0.716
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.284	0.716
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.284	0.715
M08 Juvenile arthritis	0.000	0.284	0.715
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.715	0.285	0.000
C34.2 Middle lobe, bronchus or lung	0.713	0.287	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.289	0.711
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.289	0.711
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.289	0.711
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.289	0.711
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.289	0.711
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.290	0.710
M12 Other specific arthropathies	0.000	0.291	0.709
D53 Other nutritional anaemias	0.708	0.292	0.000
C34.1 Upper lobe, bronchus or lung	0.708	0.292	0.000
K90.3 Pancreatic steatorrhoea	0.707	0.293	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.707	0.293	0.000
K90.1 Tropical sprue	0.707	0.293	0.000
C82.6 Cutaneous follicle centre lymphoma	0.000	0.297	0.703
C82.5 Diffuse follicle centre lymphoma	0.000	0.297	0.703
D89.3 Immune reconstitution syndrome	0.702	0.298	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.702	0.298	0.000
E05.5 Thyroid crisis or storm	0.701	0.298	0.000
E05.4 Thyrotoxicosis factitia	0.701	0.298	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.701	0.298	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.701	0.298	0.000
M06.1 Adult-onset Still's disease	0.000	0.310	0.690
C34.0 Main bronchus	0.690	0.310	0.000
D68.1 Hereditary factor XI deficiency	0.687	0.313	0.000
D84 Other immunodeficiencies	0.683	0.317	0.000
C21.0 Anus, unspecified	0.000	0.317	0.683
C21.1 Anal canal	0.000	0.319	0.681
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.324	0.676
C21 Malignant neoplasm of anus and anal canal	0.000	0.324	0.676
L40.8 Other psoriasis	0.000	0.327	0.673
N48.3 Priapism	0.000	0.333	0.667
D83 Common variable immunodeficiency	0.665	0.335	0.000
D69.1 Qualitative platelet defects	0.663	0.336	0.000
D86.8 Sarcoidosis of other and combined sites	0.661	0.338	0.000
D68.2 Hereditary deficiency of other clotting factors	0.661	0.339	0.000
D52.8 Other folate deficiency anaemias	0.659	0.341	0.000
D52.1 Drug-induced folate deficiency anaemia	0.659	0.341	0.000
D52.0 Dietary folate deficiency anaemia	0.659	0.341	0.000
D69.2 Other nonthrombocytopenic purpura	0.657	0.343	0.000
D69.0 Allergic purpura	0.649	0.351	0.000
M11 Other crystal arthropathies	0.000	0.356	0.644
D59 Acquired haemolytic anaemia	0.643	0.357	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.640	0.359	0.000
N49.8 Inflammatory disorders of other specified male genital organs	0.000	0.361	0.639
C34.8 Overlapping lesion of bronchus and lung	0.636	0.364	0.000
G37 Other demyelinating diseases of central nervous system	0.636	0.364	0.000
L40.1 Generalised pustular psoriasis	0.000	0.374	0.626
L40.0 Psoriasis vulgaris	0.000	0.374	0.625
M14.6 Neuropathic arthropathy	0.000	0.375	0.625
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.000	0.376	0.624
L40.4 Guttate psoriasis	0.000	0.377	0.623
L40.2 Acrodermatitis continua	0.000	0.377	0.623
D80 Immunodeficiency with predominantly antibody defects	0.618	0.382	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.385	0.615
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.385	0.614
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.385	0.614
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.385	0.614
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.385	0.614
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.385	0.614
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.385	0.614
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.385	0.614
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.390	0.610
N49.9 Inflammatory disorder of unspecified male genital organ	0.000	0.394	0.606
N49.0 Inflammatory disorders of seminal vesicle	0.000	0.394	0.606
D60-D64 Aplastic and other anaemias	0.600	0.400	0.000
M07.5 Arthropathy in ulcerative colitis	0.000	0.400	0.600
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.400	0.600
M07.2 Psoriatic spondylitis	0.000	0.400	0.600
M07.1 Arthritis mutilans	0.000	0.400	0.600
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.400	0.600
L40.3 Pustulosis palmaris et plantaris	0.000	0.404	0.596
E05.8 Other thyrotoxicosis	0.590	0.409	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.413	0.587
D51.8 Other vitamin B12 deficiency anaemias	0.583	0.416	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.579	0.421	0.000
D51.2 Transcobalamin II deficiency	0.579	0.421	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.579	0.421	0.000
D59.1 Other autoimmune haemolytic anaemias	0.571	0.429	0.000
N51.2 Balanitis in diseases classified elsewhere	0.000	0.436	0.564
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.437	0.562
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.437	0.562
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.437	0.562
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.437	0.562
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.437	0.562
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.437	0.562
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.440	0.560
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.441	0.559
D82.1 Di George's syndrome	0.556	0.444	0.000
M07.6 Other enteropathic arthropathies	0.000	0.450	0.550
D84.1 Defects in the complement system	0.544	0.456	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.457	0.543
D55 Anaemia due to enzyme disorders	0.541	0.458	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.541	0.459	0.000
N45 Orchitis and epididymitis	0.000	0.461	0.539
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.538	0.462	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.462	0.538
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.464	0.536
D82.9 Immunodeficiency associated with major defect, unspecified	0.532	0.468	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.532	0.468	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.532	0.468	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.532	0.468	0.000
D82.2 Immunodeficiency with short-limbed stature	0.532	0.468	0.000
D82.0 Wiskott-Aldrich syndrome	0.532	0.468	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.469	0.531
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.469	0.531
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.469	0.531
M12.3 Palindromic rheumatism	0.000	0.469	0.531
D53.9 Nutritional anaemia, unspecified	0.531	0.469	0.000
D61 Other aplastic anaemias	0.530	0.470	0.000
M05.28 Rheumatoid vasculitis (Other)	0.000	0.476	0.523
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.476	0.523
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.476	0.523
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.476	0.523
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.476	0.523
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.476	0.523
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.476	0.523
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.476	0.523
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.476	0.523
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.000	0.477	0.522
M14.4 Arthropathy in amyloidosis	0.000	0.477	0.522
M14.3 Lipoid dermatoarthritis	0.000	0.477	0.522
M14.1 Crystal arthropathy in other metabolic disorders	0.000	0.477	0.522
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.000	0.477	0.522
N51.8 Other disorders of male genital organs in diseases classified elsewhere	0.000	0.478	0.522
N51.1 Disorders of testis and epididymis in diseases classified elsewhere	0.000	0.478	0.522
N51.0 Disorders of prostate in diseases classified elsewhere	0.000	0.478	0.522
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.479	0.521
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.479	0.521
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.479	0.521
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.479	0.521
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.479	0.521
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.479	0.521
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.479	0.521
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.479	0.521
D69.9 Haemorrhagic condition, unspecified	0.520	0.480	0.000
G36 Other acute disseminated demyelination	0.519	0.481	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.519	0.481	0.000
D57 Sickle-cell disorders	0.517	0.482	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.485	0.515
M14.2 Diabetic arthropathy	0.000	0.485	0.515
D50 Iron deficiency anaemia	0.514	0.486	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.486	0.514
M06.28 Rheumatoid bursitis (Other)	0.000	0.486	0.514
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.486	0.514
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.486	0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.486	0.514
M06.24 Rheumatoid bursitis (Hand)	0.000	0.486	0.514
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.486	0.514
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.486	0.514
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.486	0.514
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.486	0.514
D81.9 Combined immunodeficiency, unspecified	0.514	0.486	0.000
D81.8 Other combined immunodeficiencies	0.514	0.486	0.000
D81.7 Major histocompatibility complex class II deficiency	0.514	0.486	0.000
D81.6 Major histocompatibility complex class I deficiency	0.514	0.486	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.514	0.486	0.000
D81.4 Nezelof's syndrome	0.514	0.486	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.514	0.486	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.514	0.486	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.514	0.486	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.514	0.486	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.486	0.514
M05.09 Felty's syndrome (Site unspecified)	0.000	0.486	0.513
M05.08 Felty's syndrome (Other)	0.000	0.486	0.513
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.486	0.513
M05.06 Felty's syndrome (Lower leg)	0.000	0.486	0.513
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.486	0.513
M05.04 Felty's syndrome (Hand)	0.000	0.486	0.513
M05.03 Felty's syndrome (Forearm)	0.000	0.486	0.513
M05.02 Felty's syndrome (Upper arm)	0.000	0.486	0.513
M05.01 Felty's syndrome (Shoulder region)	0.000	0.486	0.513
M05.00 Felty's syndrome (Multiple sites)	0.000	0.486	0.513
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.486	0.513
M05.18 Rheumatoid lung disease (Other)	0.000	0.486	0.513
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.486	0.513
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.486	0.513
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.486	0.513
M05.14 Rheumatoid lung disease (Hand)	0.000	0.486	0.513
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.486	0.513
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.486	0.513
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.486	0.513
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.486	0.513
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.486	0.513
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.486	0.513
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.486	0.513
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.486	0.513
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.486	0.513
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.486	0.513
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.486	0.513
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.486	0.513
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.486	0.513
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.486	0.513
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.486	0.513
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.486	0.513
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.486	0.513
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.486	0.513
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.486	0.513
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.486	0.513
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.486	0.513
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.486	0.513
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.486	0.513
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.486	0.513
M08.9 Juvenile arthritis, unspecified	0.000	0.487	0.513
M08.8 Other juvenile arthritis	0.000	0.487	0.513
M08.4 Pauciarticular juvenile arthritis	0.000	0.487	0.513
M08.3 Juvenile polyarthritis (seronegative)	0.000	0.487	0.513
M08.2 Juvenile arthritis with systemic onset	0.000	0.487	0.513
M08.1 Juvenile ankylosing spondylitis	0.000	0.487	0.513
M08.0 Juvenile rheumatoid arthritis	0.000	0.487	0.513
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.000	0.487	0.513
M09.2 Juvenile arthritis in ulcerative colitis	0.000	0.487	0.513
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.000	0.487	0.513
M09.0 Juvenile arthritis in psoriasis	0.000	0.487	0.513
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.487	0.513
M12.5 Traumatic arthropathy	0.000	0.492	0.508
M12.4 Intermittent hydrarthrosis	0.000	0.492	0.508
M12.1 Kaschin-Beck disease	0.000	0.492	0.508
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.000	0.492	0.508
D53.8 Other specified nutritional anaemias	0.508	0.492	0.000
D53.2 Scorbutic anaemia	0.508	0.492	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.508	0.492	0.000
D53.0 Protein deficiency anaemia	0.508	0.492	0.000
M12.2 Villonodular synovitis (pigmented)	0.000	0.492	0.508
D58 Other hereditary haemolytic anaemias	0.507	0.493	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.494	0.506
D56 Thalassaemia	0.498	0.502	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.497	0.503	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.505	0.495
M06.18 Adult-onset Still's disease (Other)	0.000	0.505	0.495
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.505	0.495
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.505	0.495
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.505	0.495
M06.14 Adult-onset Still's disease (Hand)	0.000	0.505	0.495
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.505	0.495
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.505	0.495
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.505	0.495
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.490	0.510	0.000
D66 Hereditary factor VIII deficiency	0.490	0.510	0.000
D84.8 Other specified immunodeficiencies	0.485	0.515	0.000
C21.2 Cloacogenic zone	0.000	0.515	0.485
D61.9 Aplastic anaemia, unspecified	0.483	0.517	0.000
D83.8 Other common variable immunodeficiencies	0.477	0.523	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.477	0.523	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.477	0.523	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.477	0.523	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.523	0.477
M12.8 Other specific arthropathies, not elsewhere classified	0.000	0.524	0.476
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.471	0.529	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.532	0.468
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.534	0.466
M11.9 Crystal arthropathy, unspecified	0.000	0.534	0.466
M11.1 Familial chondrocalcinosis	0.000	0.538	0.462
M11.0 Hydroxyapatite deposition disease	0.000	0.538	0.462
D59.8 Other acquired haemolytic anaemias	0.461	0.539	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.461	0.539	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.461	0.539	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.461	0.539	0.000
D59.3 Haemolytic-uraemic syndrome	0.461	0.539	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.461	0.539	0.000
J32.9 Chronic sinusitis, unspecified	0.000	0.539	0.461
G37.5 Concentric sclerosis [Balo]	0.456	0.544	0.000
G37.4 Subacute necrotising myelitis	0.456	0.544	0.000
G37.2 Central pontine myelinolysis	0.456	0.544	0.000
G37.1 Central demyelination of corpus callosum	0.456	0.544	0.000
G37.0 Diffuse sclerosis	0.456	0.544	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.453	0.547	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.447	0.552	0.000
M13 Other arthritis	0.000	0.553	0.447
D80.1 Nonfamilial hypogammaglobulinaemia	0.446	0.554	0.000
N40 Hyperplasia of prostate	0.000	0.555	0.445
D80.8 Other immunodeficiencies with predominantly antibody defects	0.443	0.557	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.443	0.557	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.443	0.557	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.443	0.557	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.443	0.557	0.000
N42 Other disorders of prostate	0.000	0.558	0.442
M11.8 Other specified crystal arthropathies	0.000	0.563	0.437
J32 Chronic sinusitis	0.000	0.568	0.432
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.000	0.570	0.430
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.000	0.570	0.430
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.000	0.570	0.430
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.000	0.570	0.430
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.000	0.570	0.430
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.000	0.570	0.430
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.000	0.570	0.430
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.000	0.570	0.430
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.000	0.570	0.430
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.000	0.570	0.430
M07.19 Arthritis mutilans (Site unspecified)	0.000	0.570	0.430
M07.18 Arthritis mutilans (Other)	0.000	0.570	0.430
M07.17 Arthritis mutilans (Ankle and foot)	0.000	0.570	0.430
M07.16 Arthritis mutilans (Lower leg)	0.000	0.570	0.430
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.000	0.570	0.430
M07.14 Arthritis mutilans (Hand)	0.000	0.570	0.430
M07.13 Arthritis mutilans (Forearm)	0.000	0.570	0.430
M07.12 Arthritis mutilans (Upper arm)	0.000	0.570	0.430
M07.11 Arthritis mutilans (Shoulder region)	0.000	0.570	0.430
M07.10 Arthritis mutilans (Multiple sites)	0.000	0.570	0.430
M07.29 Psoriatic spondylitis (Site unspecified)	0.000	0.570	0.430
M07.28 Psoriatic spondylitis (Other)	0.000	0.570	0.430
M07.27 Psoriatic spondylitis (Ankle and foot)	0.000	0.570	0.430
M07.26 Psoriatic spondylitis (Lower leg)	0.000	0.570	0.430
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.000	0.570	0.430
M07.24 Psoriatic spondylitis (Hand)	0.000	0.570	0.430
M07.23 Psoriatic spondylitis (Forearm)	0.000	0.570	0.430
M07.22 Psoriatic spondylitis (Upper arm)	0.000	0.570	0.430
M07.21 Psoriatic spondylitis (Shoulder region)	0.000	0.570	0.430
M07.20 Psoriatic spondylitis (Multiple sites)	0.000	0.570	0.430
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.000	0.570	0.430
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.000	0.570	0.430
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.000	0.570	0.430
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.000	0.570	0.430
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.000	0.570	0.430
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.000	0.570	0.430
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.000	0.570	0.430
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.000	0.570	0.430
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.000	0.570	0.430
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.000	0.570	0.430
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.000	0.570	0.430
M07.58 Arthropathy in ulcerative colitis (Other)	0.000	0.570	0.430
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.000	0.570	0.430
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.000	0.570	0.430
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.000	0.570	0.430
M07.54 Arthropathy in ulcerative colitis (Hand)	0.000	0.570	0.430
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.000	0.570	0.430
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.000	0.570	0.430
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.000	0.570	0.430
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.000	0.570	0.430
D83.9 Common variable immunodeficiency, unspecified	0.425	0.575	0.000
E03 Other hypothyroidism	0.198	0.577	0.225
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.422	0.578	0.000
J30-J39 Other diseases of upper respiratory tract	0.000	0.579	0.421
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.420	0.580	0.001
E00-E07 Disorders of thyroid gland	0.411	0.580	0.009
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.000	0.580	0.420
N46 Male infertility	0.001	0.582	0.417
M11.2 Other chondrocalcinosis	0.000	0.583	0.417
D61.0 Constitutional aplastic anaemia	0.416	0.584	0.000
M12.30 Palindromic rheumatism (Multiple sites)	0.000	0.590	0.410
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.405	0.594	0.000
M12.24 Villonodular synovitis (pigmented) (Hand)	0.000	0.595	0.405
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.402	0.598	0.000
J35 Chronic diseases of tonsils and adenoids	0.000	0.599	0.401
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.398	0.601	0.000
D64 Other anaemias	0.397	0.603	0.000
M07.68 Other enteropathic arthropathies (Other)	0.000	0.605	0.394
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.000	0.605	0.394
M07.66 Other enteropathic arthropathies (Lower leg)	0.000	0.605	0.394
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.000	0.605	0.394
M07.64 Other enteropathic arthropathies (Hand)	0.000	0.605	0.394
M07.63 Other enteropathic arthropathies (Forearm)	0.000	0.605	0.394
M07.62 Other enteropathic arthropathies (Upper arm)	0.000	0.605	0.394
M07.61 Other enteropathic arthropathies (Shoulder region)	0.000	0.605	0.394
M07.60 Other enteropathic arthropathies (Multiple sites)	0.000	0.605	0.394
D50.9 Iron deficiency anaemia, unspecified	0.392	0.608	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.388	0.612	0.000
D55.8 Other anaemias due to enzyme disorders	0.388	0.612	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations