TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs2858331
log Bayes Factor = 151.08
Chromosome 6   position 32,681,277  (GRCh37) Explore rs2858331 on Ensembl!
Variant rs2858331 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
1.000 0.000 0.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
D50-D53 Nutritional anaemias
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
D86 Sarcoidosis
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.001 0.999
M35.0 Sicca syndrome [Sjogren]
0.000 0.001 0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.001 0.999
D86.9 Sarcoidosis, unspecified
0.000 0.001 0.999
E14 Unspecified diabetes mellitus
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.000 0.001 0.999
E10.4 With neurological complications
0.000 0.002 0.998
E16.2 Hypoglycaemia, unspecified
0.000 0.002 0.998
D50 Iron deficiency anaemia
0.000 0.002 0.998
D50.9 Iron deficiency anaemia, unspecified
0.000 0.002 0.998
# Top node
0.000 0.002 0.998
H36 Retinal disorders in diseases classified elsewhere
0.000 0.002 0.998
H30-H36 Disorders of choroid and retina
0.000 0.004 0.996
Chapter VII Diseases of the eye and adnexa
0.000 0.004 0.996
D51 Vitamin B12 deficiency anaemia
0.000 0.005 0.995
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.994 0.006 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.009 0.991
E27.1 Primary adrenocortical insufficiency
0.000 0.009 0.991
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.010 0.990
M06 Other rheumatoid arthritis
0.000 0.011 0.989
E27 Other disorders of adrenal gland
0.000 0.011 0.989
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.012 0.988
E20-E35 Disorders of other endocrine glands
0.000 0.012 0.988
M05-M14 Inflammatory polyarthropathies
0.000 0.015 0.985
E14.9 Without complications
0.000 0.018 0.982
E10.5 With peripheral circulatory complications
0.000 0.019 0.981
E14.3 With ophthalmic complications
0.000 0.020 0.980
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.020 0.980
M05 Seropositive rheumatoid arthritis
0.000 0.022 0.978
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.026 0.974
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.027 0.973
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.029 0.971
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.032 0.968
E11 Non-insulin-dependent diabetes mellitus
0.000 0.034 0.966
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.038 0.962
E11.3 With ophthalmic complications
0.000 0.043 0.957
E10.2 With renal complications
0.000 0.043 0.957
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.054 0.946
C82.0 Small cleaved cell, follicular
0.945 0.055 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.055 0.945
Chapter VI Diseases of the nervous system
0.000 0.056 0.944
M35.1 Other overlap syndromes
0.000 0.058 0.942
D52 Folate deficiency anaemia
0.000 0.061 0.939
M20-M25 Other joint disorders
0.000 0.064 0.936
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.066 0.934
C34.9 Bronchus or lung, unspecified
0.000 0.070 0.930
L40-L45 Papulosquamous disorders
0.904 0.073 0.022
C34 Malignant neoplasm of bronchus and lung
0.000 0.076 0.924
H06.2 Dysthyroid exophthalmos
0.000 0.080 0.920
Chapter XII Diseases of the skin and subcutaneous tissue
0.002 0.081 0.917
E04 Other non-toxic goitre
0.000 0.082 0.918
L20-L30 Dermatitis and eczema
0.000 0.085 0.915
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.085 0.915
E11.1 With ketoacidosis
0.000 0.088 0.912
D86.1 Sarcoidosis of lymph nodes
0.000 0.089 0.911
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.909 0.091 0.000
E10.8 With unspecified complications
0.000 0.094 0.906
H16 Keratitis
0.000 0.096 0.904
D52.9 Folate deficiency anaemia, unspecified
0.000 0.104 0.895
C34.3 Lower lobe, bronchus or lung
0.000 0.105 0.895
D86.0 Sarcoidosis of lung
0.000 0.106 0.894
Chapter X Diseases of the respiratory system
0.000 0.107 0.893
M86-M90 Other osteopathies
0.000 0.108 0.892
E27.8 Other specified disorders of adrenal gland
0.000 0.109 0.891
H04 Disorders of lachrymal system
0.000 0.110 0.890
E10.0 With coma
0.000 0.111 0.889
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.119 0.881
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.120 0.880
L40.4 Guttate psoriasis
0.880 0.120 0.000
L40.0 Psoriasis vulgaris
0.877 0.123 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.123 0.877
E06 Thyroiditis
0.000 0.127 0.873
C82.1 Mixed small cleaved and large cell, follicular
0.866 0.134 0.000
E50-E64 Other nutritional deficiencies
0.000 0.134 0.866
K90 Intestinal malabsorption
0.000 0.134 0.866
L21 Seborrhoeic dermatitis
0.000 0.135 0.865
H00 Hordeolum and chalazion
0.000 0.142 0.858
M86 Osteomyelitis
0.000 0.143 0.857
L27 Dermatitis due to substances taken internally
0.000 0.145 0.855
E11.5 With peripheral circulatory complications
0.000 0.146 0.854
C34.0 Main bronchus
0.000 0.149 0.851
C82.3 Follicular lymphoma grade IIIa
0.851 0.149 0.000
M12 Other specific arthropathies
0.000 0.149 0.851
L30 Other dermatitis
0.000 0.153 0.847
J81 Pulmonary oedema
0.000 0.153 0.847
H16.0 Corneal ulcer
0.000 0.154 0.846
D68 Other coagulation defects
0.000 0.161 0.839
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.166 0.834
J33 Nasal polyp
0.000 0.171 0.829
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.171 0.829
H00.0 Hordeolum and other deep inflammation of eyelid
0.000 0.173 0.827
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.178 0.822
E04.0 Non-toxic diffuse goitre
0.000 0.178 0.822
J33.0 Polyp of nasal cavity
0.000 0.179 0.821
H04.8 Other disorders of lachrymal system
0.000 0.185 0.815
H33 Retinal detachments and breaks
0.000 0.186 0.814
H05 Disorders of orbit
0.000 0.187 0.813
J30-J39 Other diseases of upper respiratory tract
0.000 0.190 0.810
M06.4 Inflammatory polyarthropathy
0.000 0.194 0.806
E07 Other disorders of thyroid
0.000 0.195 0.805
H16.9 Keratitis, unspecified
0.000 0.195 0.805
M32 Systemic lupus erythematosus
0.000 0.196 0.804
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.196 0.804
C82.2 Large cell, follicular
0.804 0.196 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.197 0.803
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.198 0.802
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.201 0.799
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.000 0.201 0.799
E14.6 With other specified complications
0.000 0.202 0.798
D53 Other nutritional anaemias
0.000 0.203 0.797
L42 Pityriasis rosea
0.784 0.205 0.010
L10-L14 Bullous disorders
0.001 0.207 0.792
J33.8 Other polyp of sinus
0.000 0.209 0.791
J33.9 Nasal polyp, unspecified
0.000 0.211 0.789
C34.1 Upper lobe, bronchus or lung
0.000 0.213 0.787
L23 Allergic contact dermatitis
0.000 0.215 0.784
E10.6 With other specified complications
0.000 0.216 0.784
J80 Adult respiratory distress syndrome
0.000 0.216 0.784
H33.2 Serous retinal detachment
0.000 0.216 0.784
E14.1 With ketoacidosis
0.000 0.217 0.783
M86.9 Osteomyelitis, unspecified
0.000 0.219 0.781
L30.8 Other specified dermatitis
0.000 0.219 0.781
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.220 0.780
L40.1 Generalised pustular psoriasis
0.778 0.222 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.223 0.777
L43 Lichen planus
0.766 0.227 0.007
E06.3 Autoimmune thyroiditis
0.000 0.229 0.771
M35.8 Other specified systemic involvement of connective tissue
0.000 0.229 0.771
H55-H59 Other disorders of eye and adnexa
0.000 0.230 0.770
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.230 0.770
E34 Other endocrine disorders
0.000 0.230 0.770
E04.9 Non-toxic goitre, unspecified
0.000 0.239 0.761
E53 Deficiency of other B group vitamins
0.000 0.242 0.758
D68.0 Von Willebrand's disease
0.000 0.242 0.758
G36 Other acute disseminated demyelination
0.000 0.245 0.755
D82 Immunodeficiency associated with other major defects
0.000 0.246 0.754
L40.3 Pustulosis palmaris et plantaris
0.753 0.246 0.000
E14.8 With unspecified complications
0.000 0.247 0.753
J95-J99 Other diseases of the respiratory system
0.000 0.247 0.753
M35.2 Behcet's disease
0.000 0.248 0.752
G37 Other demyelinating diseases of central nervous system
0.000 0.250 0.750
M21 Other acquired deformities of limbs
0.000 0.250 0.750
M12.3 Palindromic rheumatism
0.000 0.251 0.749
H20 Iridocyclitis
0.000 0.254 0.746
D68.5 Primary Thrombophilia
0.000 0.260 0.740
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.261 0.739
C82.4 Follicular lymphoma grade IIIb
0.738 0.262 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.263 0.737
L44 Other papulosquamous disorders
0.722 0.264 0.014
K90.9 Intestinal malabsorption, unspecified
0.000 0.266 0.734
L13 Other bullous disorders
0.001 0.266 0.733
E61 Deficiency of other nutrient elements
0.000 0.269 0.731
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.270 0.730
M21.0 Valgus deformity, not elsewhere classified
0.000 0.273 0.727
E28 Ovarian dysfunction
0.000 0.274 0.726
M86.6 Other chronic osteomyelitis
0.000 0.274 0.726
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.274 0.726
J84 Other interstitial pulmonary diseases
0.000 0.276 0.724
E05.8 Other thyrotoxicosis
0.000 0.279 0.721
E03.1 Congenital hypothyroidism without goitre
0.000 0.279 0.721
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
E20 Hypoparathyroidism
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.717
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.717
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.717
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
D81 Combined immunodeficiencies
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
E14.7 With multiple complications
0.000 0.284 0.716
E14.0 With coma
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
E14.2 Withrenal complications
0.000 0.284 0.716
D50.1 Sideropenic dysphagia
0.000 0.284 0.716
H16.8 Other keratitis
0.000 0.284 0.716
M89 Other disorders of bone
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.285 0.715
L27.1 Localised skin eruption due to drugs and medicaments
0.000 0.285 0.715
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.286 0.714
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.287 0.713
D51.2 Transcobalamin II deficiency
0.000 0.287 0.713
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.287 0.713
C82.6 Cutaneous follicle centre lymphoma
0.713 0.287 0.000
C82.5 Diffuse follicle centre lymphoma
0.713 0.287 0.000
L30.9 Dermatitis, unspecified
0.000 0.288 0.712
H33.3 Retinal breaks without detachment
0.000 0.290 0.710
M06.8 Other specified rheumatoid arthritis
0.000 0.291 0.709
M06.2 Rheumatoid bursitis
0.000 0.291 0.709
M06.1 Adult-onset Still's disease
0.000 0.291 0.709
E27.5 Adrenomedullary hyperfunction
0.000 0.291 0.709
E27.0 Other adrenocortical overactivity
0.000 0.291 0.709
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.292 0.708
E32 Diseases of thymus
0.000 0.292 0.708
E31 Polyglandular dysfunction
0.000 0.292 0.708
E30 Disorders of puberty, not elsewhere classified
0.000 0.292 0.708
L40.8 Other psoriasis
0.707 0.292 0.000
M35.7 Hypermobility syndrome
0.000 0.293 0.706
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.294 0.706
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.294 0.706
M06.3 Rheumatoid nodule
0.000 0.294 0.706
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.297 0.703
E14.5 With peripheral circulatory complications
0.000 0.298 0.702
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.298 0.702
H57 Other disorders of eye and adnexa
0.000 0.298 0.702
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.298 0.701
M05.1 Rheumatoid lung disease
0.000 0.298 0.701
M05.0 Felty's syndrome
0.000 0.298 0.701
H19.1 Herpesviral keratitis and keratoconjunctivitis
0.000 0.299 0.701
M05.2 Rheumatoid vasculitis
0.000 0.299 0.701
M08 Juvenile arthritis
0.000 0.299 0.701
D67 Hereditary factor IX deficiency
0.000 0.299 0.701
M86.8 Other osteomyelitis
0.000 0.300 0.700
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.000 0.300 0.700
H16.3 Interstitial and deep keratitis
0.000 0.300 0.700
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.302 0.698
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.302 0.698
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.302 0.698
L28 Lichen simplex chronicus and prurigo
0.000 0.302 0.697
M60-M63 Disorders of muscles
0.000 0.303 0.697
E11.7 With multiple complications
0.000 0.307 0.693
L13.0 Dermatitis herpetiformis
0.000 0.308 0.691
E34.0 Carcinoid syndrome
0.000 0.309 0.691
H05.0 Acute inflammation of orbit
0.000 0.310 0.690
E07.8 Other specified disorders of thyroid
0.000 0.312 0.688
G30-G32 Other degenerative diseases of the nervous system
0.000 0.313 0.687
H04.4 Chronic inflammation of lachrymal passages
0.000 0.314 0.686
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.314 0.685
E03.8 Other specified hypothyroidism
0.000 0.315 0.685
L23.9 Allergic contact dermatitis, unspecified cause
0.000 0.316 0.684
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.316 0.684
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.316 0.684
H30 Chorioretinal inflammation
0.000 0.319 0.681
D50.8 Other iron deficiency anaemias
0.000 0.319 0.681
H15 Disorders of sclera
0.000 0.321 0.679
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.321 0.679
H06.3 Other disorders of orbit in diseases classified elsewhere
0.000 0.322 0.677
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.000 0.322 0.677
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.000 0.322 0.677
C34.2 Middle lobe, bronchus or lung
0.000 0.323 0.677
H35 Other retinal disorders
0.000 0.324 0.676
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.325 0.675
L41 Parapsoriasis
0.659 0.325 0.016
E40-E46 Malnutrition
0.000 0.326 0.674
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.326 0.674
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.326 0.674
D52.8 Other folate deficiency anaemias
0.000 0.327 0.673
D52.1 Drug-induced folate deficiency anaemia
0.000 0.327 0.673
D52.0 Dietary folate deficiency anaemia
0.000 0.327 0.673
H18 Other disorders of cornea
0.000 0.327 0.673
M89.8 Other specified disorders of bone
0.000 0.329 0.671
C44.3 Skin of other and unspecified parts of face
0.671 0.329 0.000
J20-J22 Other acute lower respiratory infections
0.000 0.330 0.670
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.332 0.668
D60-D64 Aplastic and other anaemias
0.000 0.334 0.666
C44 Other malignant neoplasms of skin
0.665 0.335 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.648 0.335 0.016
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.336 0.664
D69 Purpura and other haemorrhagic conditions
0.000 0.339 0.661
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.339 0.661
H18.6 Keratoconus
0.000 0.341 0.659
E04.8 Other specified non-toxic goitre
0.000 0.342 0.658
E51 Thiamine deficiency
0.000 0.342 0.658
L24 Irritant contact dermatitis
0.000 0.344 0.656
L26 Exfoliative dermatitis
0.000 0.344 0.656
L22 Diaper [napkin] dermatitis
0.000 0.344 0.656
E53.8 Deficiency of other specified B group vitamins
0.000 0.345 0.655
C44.5 Skin of trunk
0.655 0.345 0.000
C44.7 Skin of lower limb, including hip
0.655 0.345 0.000
E06.9 Thyroiditis, unspecified
0.000 0.345 0.655
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.001 0.347 0.652
E22 Hyperfunction of pituitary gland
0.000 0.347 0.653
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.000 0.347 0.653
D53.9 Nutritional anaemia, unspecified
0.000 0.348 0.652
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.349 0.651
M89.87 Other specified disorders of bone (Ankle and foot)
0.000 0.351 0.649
C34.8 Overlapping lesion of bronchus and lung
0.000 0.351 0.649
H16.4 Corneal neovascularisation
0.000 0.352 0.648
D86.3 Sarcoidosis of skin
0.000 0.352 0.647
L25 Unspecified contact dermatitis
0.000 0.353 0.646
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.354 0.646
H20.1 Chronic iridocyclitis
0.000 0.354 0.646
E14.4 With neurological complications
0.000 0.355 0.645
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.000 0.356 0.644
E29 Testicular dysfunction
0.000 0.356 0.644
L27.2 Dermatitis due to ingested food
0.000 0.357 0.643
L43.0 Hypertrophic lichen planus
0.636 0.359 0.004
H35.8 Other specified retinal disorders
0.000 0.360 0.640
L43.9 Lichen planus, unspecified
0.638 0.361 0.001
H04.0 Dacryoadenitis
0.000 0.362 0.638
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.362 0.638
D68.4 Acquired coagulation factor deficiency
0.000 0.365 0.635
E11.8 With unspecified complications
0.000 0.366 0.634
D84 Other immunodeficiencies
0.000 0.366 0.634
L29 Pruritus
0.000 0.367 0.633
L30.4 Erythema intertrigo
0.000 0.367 0.633
H04.6 Other changes in lachrymal passages
0.000 0.368 0.632
H05.9 Disorder of orbit, unspecified
0.000 0.368 0.632
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.002 0.369 0.629
C91 Lymphoid leukaemia
0.000 0.372 0.628
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.000 0.372 0.628
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.372 0.628
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.373 0.627
E11.2 With renal complications
0.000 0.373 0.627
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.373 0.626
M33 Dermatopolymyositis
0.000 0.373 0.626
H57.0 Anomalies of pupillary function
0.000 0.374 0.626
E06.5 Other chronic thyroiditis
0.000 0.374 0.626
E06.4 Drug-induced thyroiditis
0.000 0.374 0.626
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.374 0.626
E06.1 Subacute thyroiditis
0.000 0.374 0.626
E06.0 Acute thyroiditis
0.000 0.374 0.626
M86.98 Osteomyelitis, unspecified (Other)
0.000 0.375 0.625
C91.1 Chronic lymphocytic leukaemia
0.000 0.375 0.625
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.376 0.624
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.377 0.623
D86.8 Sarcoidosis of other and combined sites
0.000 0.378 0.622
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.378 0.622
H33.4 Traction detachment of retina
0.000 0.378 0.621
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.379 0.621
E63 Other nutritional deficiencies
0.000 0.379 0.621
E50 Vitamin A deficiency
0.000 0.379 0.621
E60 Dietary zinc deficiency
0.000 0.379 0.621
E59 Dietary selenium deficiency
0.000 0.379 0.621
E54 Ascorbic acid deficiency
0.000 0.379 0.621
E52 Niacin deficiency [pellagra]
0.000 0.379 0.621
Chapter II Neoplasms
0.001 0.379 0.620
K90.3 Pancreatic steatorrhoea
0.000 0.379 0.621
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.379 0.621
K90.1 Tropical sprue
0.000 0.379 0.621
L21.8 Other seborrhoeic dermatitis
0.000 0.380 0.620
L21.1 Seborrhoeic infantile dermatitis
0.000 0.380 0.620
L21.0 Seborrhoea capitis
0.000 0.380 0.620
M86.1 Other acute osteomyelitis
0.000 0.380 0.620
M14 Arthropathies in other diseases classified elsewhere
0.000 0.381 0.619
J40-J47 Chronic lower respiratory diseases
0.000 0.383 0.617
D68.8 Other specified coagulation defects
0.000 0.384 0.616
M00-M03 Infectious arthropathies
0.000 0.384 0.615
H04.1 Other disorders of lachrymal gland
0.000 0.385 0.615
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.385 0.615
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.386 0.614
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.386 0.614
M86.5 Other chronic haematogenous osteomyelitis
0.000 0.386 0.614
M86.4 Chronic osteomyelitis with draining sinus
0.000 0.386 0.614
M86.3 Chronic multifocal osteomyelitis
0.000 0.386 0.614
M86.2 Subacute osteomyelitis
0.000 0.386 0.614
M86.0 Acute haematogenous osteomyelitis
0.000 0.386 0.614
E16.1 Other hypoglycaemia
0.000 0.386 0.614
K90.8 Other intestinal malabsorption
0.000 0.387 0.613
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.387 0.613
L27.8 Dermatitis due to other substances taken internally
0.000 0.387 0.613
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.000 0.388 0.612
J39 Other diseases of upper respiratory tract
0.000 0.390 0.610
M12.5 Traumatic arthropathy
0.000 0.390 0.610
M12.4 Intermittent hydrarthrosis
0.000 0.390 0.610
M12.1 Kaschin-Beck disease
0.000 0.390 0.610
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.390 0.610
D83 Common variable immunodeficiency
0.000 0.392 0.608
L30.5 Pityriasis alba
0.000 0.393 0.607
L30.2 Cutaneous autosensitisation
0.000 0.393 0.607
L30.1 Dyshidrosis [pompholyx]
0.000 0.393 0.607
L30.0 Nummular dermatitis
0.000 0.393 0.607
H05.2 Exophthalmic conditions
0.000 0.393 0.607
H57.1 Ocular pain
0.000 0.394 0.606
M12.2 Villonodular synovitis (pigmented)
0.000 0.394 0.606
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere
0.000 0.395 0.605
M34 Systemic sclerosis
0.000 0.395 0.605
D68.6 Other Thrombophilia
0.000 0.395 0.604
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.396 0.604
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.000 0.396 0.604
L50-L54 Urticaria and erythema
0.001 0.397 0.603
L11 Other acantholytic disorders
0.001 0.397 0.602
E11.6 With other specified complications
0.000 0.398 0.602
E61.1 Iron deficiency
0.000 0.398 0.602
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.400 0.599
L44.0 Pityriasis rubra pilaris
0.591 0.401 0.008
M12.30 Palindromic rheumatism (Multiple sites)
0.000 0.401 0.599
C81 Hodgkin's disease
0.000 0.401 0.599
G36.0 Neuromyelitis optica [Devic]
0.000 0.402 0.598
M86.96 Osteomyelitis, unspecified (Lower leg)
0.000 0.403 0.597
M06.34 Rheumatoid nodule (Hand)
0.000 0.403 0.597
C44.2 Skin of ear and external auricular canal
0.597 0.403 0.000
E55 Vitamin D deficiency
0.000 0.404 0.596
E53.9 Vitamin B deficiency, unspecified
0.000 0.405 0.595
H17 Corneal scars and opacities
0.000 0.405 0.595
M31 Other necrotising vasculopathies
0.000 0.405 0.594
M88 Paget's disease of bone [osteitis deformans]
0.000 0.406 0.594
M86.86 Other osteomyelitis (Lower leg)
0.000 0.408 0.592
L23.5 Allergic contact dermatitis due to other chemical products
0.000 0.408 0.592
H16.1 Other superficial keratitis without conjunctivitis
0.000 0.408 0.592
J33.1 Polypoid sinus degeneration
0.000 0.409 0.591
M32.8 Other forms of systemic lupus erythematosus
0.000 0.409 0.591
M07 Psoriatic and enteropathic arthropathies
0.173 0.410 0.417
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.411 0.589
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.000 0.412 0.588
M86.94 Osteomyelitis, unspecified (Hand)
0.000 0.413 0.586
E56 Other vitamin deficiencies
0.000 0.414 0.586
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.415 0.585
D80 Immunodeficiency with predominantly antibody defects
0.000 0.415 0.585
E27.2 Addisonian crisis
0.000 0.416 0.584
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.416 0.584
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.416 0.584
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.000 0.417 0.583
H05.3 Deformity of orbit
0.000 0.417 0.583
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.418 0.582
L28.1 Prurigo nodularis
0.000 0.420 0.580
D82.1 Di George's syndrome
0.000 0.421 0.579
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.422 0.578
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.422 0.578
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.422 0.578
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.422 0.578
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.422 0.578
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.422 0.578
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.422 0.578
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.422 0.578
E07.1 Dyshormogenetic goitre
0.000 0.422 0.577
E07.0 Hypersecretion of calcitonin
0.000 0.422 0.577
H04.9 Disorder of lachrymal system, unspecified
0.000 0.423 0.577
M32.9 Systemic lupus erythematosus, unspecified
0.000 0.423 0.576
M32.0 Drug-induced systemic lupus erythematosus
0.000 0.423 0.576
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.424 0.576
H35.6 Retinal haemorrhage
0.000 0.424 0.576
E61.2 Magnesium deficiency
0.000 0.425 0.575
H05.1 Chronic inflammatory disorders of orbit
0.000 0.426 0.574
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.426 0.574
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere
0.000 0.427 0.573
H19.0 Scleritis and episcleritis in diseases classified elsewhere
0.000 0.427 0.573
D53.8 Other specified nutritional anaemias
0.000 0.428 0.571
D53.2 Scorbutic anaemia
0.000 0.428 0.571
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.428 0.571
D53.0 Protein deficiency anaemia
0.000 0.428 0.571
G83 Other paralytic syndromes
0.000 0.430 0.570
L14 Bullous disorders in diseases classified elsewhere
0.001 0.431 0.568
J47 Bronchiectasis
0.000 0.431 0.569
H58.8 Visual disturbances in diseases classified elsewhere
0.000 0.432 0.568
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.000 0.432 0.568
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.433 0.567
H34 Retinal vascular occlusions
0.000 0.433 0.567
C81.9 Hodgkin's disease, unspecified
0.000 0.433 0.567
E28.2 Polycystic ovarian syndrome
0.000 0.433 0.567
D68.1 Hereditary factor XI deficiency
0.000 0.434 0.566
M90 Osteopathies in diseases classified elsewhere
0.000 0.434 0.565
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.435 0.565
E27.9 Disorder of adrenal gland, unspecified
0.000 0.436 0.564
D55-D59 Haemolytic anaemias
0.000 0.437 0.563
L23.8 Allergic contact dermatitis due to other agents
0.000 0.437 0.562
L23.7 Allergic contact dermatitis due to plants, except food
0.000 0.437 0.562
L23.6 Allergic contact dermatitis due to food in contact with the skin
0.000 0.437 0.562
L23.4 Allergic contact dermatitis due to dyes
0.000 0.437 0.562
L23.3 Allergic contact dermatitis due to drugs in contact with the skin
0.000 0.437 0.562
L23.2 Allergic contact dermatitis due to cosmetics
0.000 0.437 0.562
L23.0 Allergic contact dermatitis due to metals
0.000 0.437 0.562
H05.4 Enophthalmos
0.000 0.439 0.561
M86.93 Osteomyelitis, unspecified (Forearm)
0.000 0.440 0.560
M86.92 Osteomyelitis, unspecified (Upper arm)
0.000 0.440 0.560
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.000 0.440 0.560
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.000 0.440 0.560
M89.5 Osteolysis
0.000 0.440 0.560
H16.2 Keratoconjunctivitis
0.000 0.440 0.560
J21 Acute bronchiolitis
0.000 0.440 0.559
M86.87 Other osteomyelitis (Ankle and foot)
0.000 0.441 0.559
M86.66 Other chronic osteomyelitis (Lower leg)
0.000 0.442 0.557

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2024 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.