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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2858333
log Bayes Factor = 114.203
Chromosome 6   position 32,681,085  (GRCh37) Explore rs2858333 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J47 Bronchiectasis
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.001 0.999
M05 Seropositive rheumatoid arthritis
0.000 0.002 0.998
Chapter X Diseases of the respiratory system
0.000 0.002 0.998
E10.4 With neurological complications
0.000 0.002 0.998
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.998 0.002 0.000
M05-M14 Inflammatory polyarthropathies
0.000 0.002 0.998
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.003 0.997
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.003 0.997
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.004 0.996
K90.0 Coeliac disease
0.000 0.005 0.995
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.008 0.992
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.012 0.988
J20-J22 Other acute lower respiratory infections
0.000 0.016 0.984
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.019 0.981
E10.5 With peripheral circulatory complications
0.000 0.022 0.978
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.024 0.976
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.024 0.976
E10.2 With renal complications
0.000 0.026 0.974
J22 Unspecified acute lower respiratory infection
0.000 0.029 0.971
E05.9 Thyrotoxicosis, unspecified
0.000 0.032 0.968
L40.0 Psoriasis vulgaris
0.965 0.035 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.040 0.960
E16 Other disorders of pancreatic internal secretion
0.000 0.040 0.960
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.042 0.958
E14 Unspecified diabetes mellitus
0.000 0.045 0.955
M06.3 Rheumatoid nodule
0.000 0.050 0.950
E16.2 Hypoglycaemia, unspecified
0.000 0.050 0.950
J80 Adult respiratory distress syndrome
0.000 0.051 0.949
M06.0 Seronegative rheumatoid arthritis
0.000 0.052 0.948
J81 Pulmonary oedema
0.000 0.055 0.945
J84 Other interstitial pulmonary diseases
0.000 0.056 0.944
E14.3 With ophthalmic complications
0.000 0.065 0.935
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.074 0.926
M35.1 Other overlap syndromes
0.000 0.078 0.922
E06 Thyroiditis
0.000 0.078 0.922
M06.34 Rheumatoid nodule (Hand)
0.000 0.089 0.911
E04 Other non-toxic goitre
0.000 0.090 0.910
E10.0 With coma
0.000 0.136 0.864
L40.4 Guttate psoriasis
0.860 0.140 0.000
E50-E64 Other nutritional deficiencies
0.000 0.143 0.857
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.145 0.855
E06.3 Autoimmune thyroiditis
0.000 0.145 0.855
E10.8 With unspecified complications
0.000 0.148 0.852
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.155 0.845
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.165 0.835
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.167 0.833
J95-J99 Other diseases of the respiratory system
0.000 0.168 0.832
E04.0 Non-toxic diffuse goitre
0.000 0.180 0.820
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.185 0.815
L40.1 Generalised pustular psoriasis
0.813 0.187 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.188 0.812
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.189 0.811
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.196 0.804
E04.2 Non-toxic multinodular goitre
0.000 0.207 0.793
L40.8 Other psoriasis
0.789 0.211 0.000
M35.2 Behcet's disease
0.000 0.214 0.786
J42 Unspecified chronic bronchitis
0.000 0.216 0.784
J46 Status asthmaticus
0.000 0.219 0.781
J21 Acute bronchiolitis
0.000 0.221 0.779
E07 Other disorders of thyroid
0.000 0.222 0.778
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.223 0.777
M06.4 Inflammatory polyarthropathy
0.000 0.225 0.775
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.236 0.764
E10.6 With other specified complications
0.000 0.236 0.764
L40.3 Pustulosis palmaris et plantaris
0.764 0.236 0.000
J84.8 Other specified interstitial pulmonary diseases
0.000 0.242 0.758
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.247 0.753
J00-J06 Acute upper respiratory infections
0.000 0.254 0.746
J41 Simple and mucopurulent chronic bronchitis
0.000 0.255 0.745
E61 Deficiency of other nutrient elements
0.000 0.267 0.733
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.269 0.731
H36 Retinal disorders in diseases classified elsewhere
0.000 0.269 0.731
E05.8 Other thyrotoxicosis
0.000 0.273 0.727
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.273 0.727
M12 Other specific arthropathies
0.000 0.274 0.726
E55 Vitamin D deficiency
0.000 0.278 0.722
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.717
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.717
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.717
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
M05.8 Other seropositive rheumatoid arthritis
0.000 0.284 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.284 0.716
M05.2 Rheumatoid vasculitis
0.000 0.284 0.716
M05.1 Rheumatoid lung disease
0.000 0.284 0.716
M05.0 Felty's syndrome
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.285 0.715
M08 Juvenile arthritis
0.000 0.285 0.715
E04.9 Non-toxic goitre, unspecified
0.000 0.285 0.715
E06.9 Thyroiditis, unspecified
0.000 0.295 0.705
E20-E35 Disorders of other endocrine glands
0.000 0.297 0.703
E14.1 With ketoacidosis
0.000 0.298 0.702
E15 Nondiabetic hypoglycaemic coma
0.000 0.300 0.700
M35.8 Other specified systemic involvement of connective tissue
0.000 0.303 0.696
E14.5 With peripheral circulatory complications
0.000 0.306 0.694
M20-M25 Other joint disorders
0.000 0.306 0.694
J20 Acute bronchitis
0.000 0.308 0.692
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.312 0.688
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.312 0.688
E16.4 Abnormal secretion of gastrin
0.000 0.312 0.688
E16.3 Increased secretion of glucagon
0.000 0.312 0.688
M34 Systemic sclerosis
0.000 0.315 0.685
E14.7 With multiple complications
0.000 0.315 0.685
E14.6 With other specified complications
0.000 0.315 0.685
E14.0 With coma
0.000 0.315 0.685
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.318 0.682
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.319 0.681
M06.38 Rheumatoid nodule (Other)
0.000 0.319 0.681
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.319 0.681
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.319 0.681
M06.33 Rheumatoid nodule (Forearm)
0.000 0.319 0.681
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.319 0.681
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.319 0.681
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.320 0.680
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.320 0.680
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.320 0.680
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.320 0.680
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.320 0.680
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.320 0.680
J84.0 Alveolar and parietoalveolar conditions
0.000 0.323 0.677
E27 Other disorders of adrenal gland
0.000 0.327 0.673
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.328 0.672
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.330 0.670
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.332 0.668
E14.8 With unspecified complications
0.000 0.335 0.665
E14.2 Withrenal complications
0.000 0.335 0.664
E06.5 Other chronic thyroiditis
0.000 0.339 0.661
E06.4 Drug-induced thyroiditis
0.000 0.339 0.661
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.339 0.661
E06.1 Subacute thyroiditis
0.000 0.339 0.661
E06.0 Acute thyroiditis
0.000 0.339 0.661
E27.1 Primary adrenocortical insufficiency
0.000 0.340 0.660
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.344 0.655
M34.9 Systemic sclerosis, unspecified
0.000 0.347 0.653
E04.8 Other specified non-toxic goitre
0.000 0.348 0.652
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.360 0.640
E14.4 With neurological complications
0.000 0.361 0.639
J00 Acute nasopharyngitis [common cold]
0.000 0.361 0.639
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.362 0.638
M35.7 Hypermobility syndrome
0.000 0.365 0.635
M14 Arthropathies in other diseases classified elsewhere
0.000 0.368 0.632
J21.9 Acute bronchiolitis, unspecified
0.000 0.368 0.632
E40-E46 Malnutrition
0.000 0.370 0.629
E55.9 Vitamin D deficiency, unspecified
0.000 0.375 0.625
E07.8 Other specified disorders of thyroid
0.000 0.378 0.622
M10 Gout
0.000 0.385 0.615
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.385 0.614
E63 Other nutritional deficiencies
0.000 0.385 0.614
E51 Thiamine deficiency
0.000 0.385 0.614
E50 Vitamin A deficiency
0.000 0.385 0.614
E60 Dietary zinc deficiency
0.000 0.385 0.614
E59 Dietary selenium deficiency
0.000 0.385 0.614
E54 Ascorbic acid deficiency
0.000 0.385 0.614
E52 Niacin deficiency [pellagra]
0.000 0.385 0.614
E14.9 Without complications
0.000 0.388 0.612
J99.0 Rheumatoid lung disease
0.000 0.391 0.609
J98 Other respiratory disorders
0.000 0.391 0.609
E61.1 Iron deficiency
0.000 0.391 0.609
E53 Deficiency of other B group vitamins
0.000 0.396 0.604
# Top node
0.000 0.401 0.599
E56 Other vitamin deficiencies
0.000 0.403 0.597
J96 Respiratory failure, not elsewhere classified
0.000 0.403 0.597
M34.8 Other forms of systemic sclerosis
0.000 0.404 0.596
M34.1 CR(E)ST syndrome
0.000 0.405 0.595
J01 Acute sinusitis
0.000 0.406 0.594
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.410 0.590
E27.8 Other specified disorders of adrenal gland
0.000 0.412 0.588
E61.2 Magnesium deficiency
0.000 0.415 0.585
J40 Bronchitis, not specified as acute or chronic
0.000 0.417 0.583
J60-J70 Lung diseases due to external agents
0.000 0.421 0.579
E28 Ovarian dysfunction
0.000 0.427 0.573
J43 Emphysema
0.000 0.430 0.570
J98.9 Respiratory disorder, unspecified
0.000 0.431 0.569
J41.0 Simple chronic bronchitis
0.000 0.437 0.563
E11 Non-insulin-dependent diabetes mellitus
0.000 0.439 0.561
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.441 0.559
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.441 0.558
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.441 0.558
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.441 0.558
J33 Nasal polyp
0.000 0.442 0.558
E07.1 Dyshormogenetic goitre
0.000 0.442 0.558
E07.0 Hypersecretion of calcitonin
0.000 0.442 0.558
M12.3 Palindromic rheumatism
0.000 0.444 0.556
M20 Acquired deformities of fingers and toes
0.000 0.444 0.556
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.444 0.556
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.444 0.556
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.444 0.556
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.444 0.556
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.444 0.556
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.444 0.556
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.444 0.556
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.444 0.556
J30-J39 Other diseases of upper respiratory tract
0.000 0.446 0.554
E07.9 Disorder of thyroid, unspecified
0.000 0.446 0.554
M11 Other crystal arthropathies
0.000 0.453 0.547
E29 Testicular dysfunction
0.000 0.454 0.546
E11.3 With ophthalmic complications
0.000 0.458 0.542
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.461 0.538
H30-H36 Disorders of choroid and retina
0.000 0.462 0.538
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.462 0.538
E58 Dietary calcium deficiency
0.000 0.463 0.537
J33.9 Nasal polyp, unspecified
0.000 0.464 0.536
E16.1 Other hypoglycaemia
0.000 0.465 0.535
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.465 0.534
J41.1 Mucopurulent chronic bronchitis
0.000 0.465 0.534
Chapter VII Diseases of the eye and adnexa
0.000 0.466 0.534
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.470 0.530
E23 Hypofunction and other disorders of pituitary gland
0.000 0.473 0.527
M60-M63 Disorders of muscles
0.000 0.474 0.526
E61.9 Deficiency of nutrient element, unspecified
0.000 0.474 0.526
E61.8 Deficiency of other specified nutrient elements
0.000 0.474 0.526
E61.7 Deficiency of multiple nutrient elements
0.000 0.474 0.526
E61.6 Vanadium deficiency
0.000 0.474 0.526
E61.5 Molybdenum deficiency
0.000 0.474 0.526
E61.4 Chromium deficiency
0.000 0.474 0.526
E61.3 Manganese deficiency
0.000 0.474 0.526
E61.0 Copper deficiency
0.000 0.474 0.526
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.476 0.524
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.477 0.523
M20.3 Other deformity of hallux (acquired)
0.000 0.479 0.521
M32 Systemic lupus erythematosus
0.000 0.479 0.521
E34 Other endocrine disorders
0.000 0.479 0.521
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.479 0.520
M12.5 Traumatic arthropathy
0.000 0.479 0.520
M12.4 Intermittent hydrarthrosis
0.000 0.479 0.520
M12.1 Kaschin-Beck disease
0.000 0.479 0.520
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.479 0.520
J33.0 Polyp of nasal cavity
0.000 0.481 0.519
J04 Acute laryngitis and tracheitis
0.000 0.481 0.518
E55.0 Rickets, active
0.000 0.482 0.518
H55-H59 Other disorders of eye and adnexa
0.000 0.484 0.516
E26 Hyperaldosteronism
0.000 0.485 0.515
M10.0 Idiopathic gout
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.486 0.514
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.486 0.514
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.486 0.514
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.486 0.514
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.486 0.514
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.486 0.514
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.486 0.514
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.486 0.514
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.486 0.514
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.486 0.514
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
J33.8 Other polyp of sinus
0.000 0.486 0.514
M05.09 Felty's syndrome (Site unspecified)
0.000 0.487 0.513
M05.08 Felty's syndrome (Other)
0.000 0.487 0.513
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.487 0.513
M05.06 Felty's syndrome (Lower leg)
0.000 0.487 0.513
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.487 0.513
M05.04 Felty's syndrome (Hand)
0.000 0.487 0.513
M05.03 Felty's syndrome (Forearm)
0.000 0.487 0.513
M05.02 Felty's syndrome (Upper arm)
0.000 0.487 0.513
M05.01 Felty's syndrome (Shoulder region)
0.000 0.487 0.513
M05.00 Felty's syndrome (Multiple sites)
0.000 0.487 0.513
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.487 0.513
M05.18 Rheumatoid lung disease (Other)
0.000 0.487 0.513
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.487 0.513
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.487 0.513
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.487 0.513
M05.14 Rheumatoid lung disease (Hand)
0.000 0.487 0.513
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.487 0.513
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.487 0.513
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.487 0.513
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.487 0.513
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.487 0.513
M05.28 Rheumatoid vasculitis (Other)
0.000 0.487 0.513
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.487 0.513
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.487 0.513
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.487 0.513
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.487 0.513
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.487 0.513
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.487 0.513
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.487 0.513
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.487 0.513
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.487 0.513
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.487 0.513
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.487 0.513
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.487 0.513
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.487 0.513
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.487 0.513
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.487 0.513
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.487 0.513
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.487 0.513
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.487 0.513
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.487 0.513
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.487 0.513
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.487 0.513
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.487 0.513
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.487 0.513
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.487 0.513
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.487 0.513
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.487 0.513
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.487 0.513
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.487 0.513
J98.4 Other disorders of lung
0.000 0.487 0.513
M08.9 Juvenile arthritis, unspecified
0.000 0.487 0.513
M08.8 Other juvenile arthritis
0.000 0.487 0.513
M08.4 Pauciarticular juvenile arthritis
0.000 0.487 0.513
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.487 0.513
M08.2 Juvenile arthritis with systemic onset
0.000 0.487 0.513
M08.1 Juvenile ankylosing spondylitis
0.000 0.487 0.513
M08.0 Juvenile rheumatoid arthritis
0.000 0.487 0.513
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.487 0.513
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.487 0.513
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.487 0.513
M09.0 Juvenile arthritis in psoriasis
0.000 0.487 0.513
J20.9 Acute bronchitis, unspecified
0.000 0.488 0.512
H57 Other disorders of eye and adnexa
0.000 0.493 0.507
J09-J18 Influenza and pneumonia
0.000 0.495 0.505
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.496 0.504
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.496 0.504
E32 Diseases of thymus
0.000 0.496 0.504
E31 Polyglandular dysfunction
0.000 0.496 0.504
E30 Disorders of puberty, not elsewhere classified
0.000 0.496 0.504
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.497 0.503
D68 Other coagulation defects
0.000 0.500 0.500
D69 Purpura and other haemorrhagic conditions
0.000 0.500 0.500
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.502 0.498
J98.1 Pulmonary collapse
0.000 0.502 0.498
J20.7 Acute bronchitis due to echovirus
0.000 0.504 0.496
J20.6 Acute bronchitis due to rhinovirus
0.000 0.504 0.496
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.504 0.496
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.504 0.496
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.504 0.496
J20.2 Acute bronchitis due to streptococcus
0.000 0.504 0.496
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.504 0.496
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.504 0.496
L40-L45 Papulosquamous disorders
0.444 0.507 0.049
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.509 0.491
M34.0 Progressive systemic sclerosis
0.000 0.509 0.491
M12.2 Villonodular synovitis (pigmented)
0.000 0.509 0.490
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.512 0.488
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.514 0.486
E27.5 Adrenomedullary hyperfunction
0.000 0.517 0.483
E27.0 Other adrenocortical overactivity
0.000 0.517 0.483
J06.9 Acute upper respiratory infection, unspecified
0.000 0.522 0.478
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.522 0.477
J01.9 Acute sinusitis, unspecified
0.000 0.527 0.473
M20.0 Deformity of finger(s)
0.000 0.528 0.472
M40-M43 Deforming dorsopathies
0.000 0.528 0.472
E53.9 Vitamin B deficiency, unspecified
0.000 0.528 0.472
E28.2 Polycystic ovarian syndrome
0.000 0.529 0.471
E11.1 With ketoacidosis
0.000 0.530 0.470
M24 Other specific joint derangements
0.000 0.531 0.469
E20 Hypoparathyroidism
0.000 0.532 0.468
D60-D64 Aplastic and other anaemias
0.000 0.532 0.468
H57.0 Anomalies of pupillary function
0.000 0.534 0.466
J10 Influenza due to identified influenza virus
0.000 0.534 0.466
J64 Unspecified pneumoconiosis
0.000 0.534 0.466
J20.8 Acute bronchitis due to other specified organisms
0.000 0.536 0.464
M00-M03 Infectious arthropathies
0.000 0.538 0.462
J02 Acute pharyngitis
0.000 0.539 0.461
G36 Other acute disseminated demyelination
0.000 0.542 0.457
E65-E68 Obesity and other hyperalimentation
0.000 0.543 0.457
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.544 0.456
E13 Other specified diabetes mellitus
0.001 0.544 0.455
G37 Other demyelinating diseases of central nervous system
0.000 0.545 0.455
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.547 0.453
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.547 0.453
M14.4 Arthropathy in amyloidosis
0.000 0.547 0.453
M14.3 Lipoid dermatoarthritis
0.000 0.547 0.453
M14.2 Diabetic arthropathy
0.000 0.547 0.453
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.547 0.453
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.547 0.453
J43.2 Centrilobular emphysema
0.000 0.548 0.451
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.548 0.451
E45 Retarded development following protein-energy malnutrition
0.000 0.548 0.451
E43 Unspecified severe protein-energy malnutrition
0.000 0.548 0.451
E42 Marasmic kwashiorkor
0.000 0.548 0.451
E41 Nutritional marasmus
0.000 0.548 0.451
E40 Kwashiorkor
0.000 0.548 0.451
M07 Psoriatic and enteropathic arthropathies
0.006 0.551 0.443
D68.9 Coagulation defect, unspecified
0.000 0.552 0.448
M30 Polyarteritis nodosa and related conditions
0.000 0.552 0.448
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.558 0.442
J01.0 Acute maxillary sinusitis
0.000 0.558 0.442
M10.4 Other secondary gout
0.000 0.559 0.441
M10.3 Gout due to impairment of renal function
0.000 0.559 0.441
M10.2 Drug-induced gout
0.000 0.559 0.441
M10.1 Lead-induced gout
0.000 0.559 0.441
E50.9 Vitamin A deficiency, unspecified
0.000 0.559 0.441
E50.8 Other manifestations of vitamin A deficiency
0.000 0.559 0.441
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.559 0.441
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.559 0.441
E50.5 Vitamin A deficiency with night blindness
0.000 0.559 0.441
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.559 0.441
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.559 0.441
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.559 0.441
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.559 0.441
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.559 0.441
E51.9 Thiamine deficiency, unspecified
0.000 0.559 0.441
E51.8 Other manifestations of thiamine deficiency
0.000 0.559 0.441
E51.2 Wernicke's encephalopathy
0.000 0.559 0.441
E51.1 Beriberi
0.000 0.559 0.441
E63.9 Nutritional deficiency, unspecified
0.000 0.559 0.441
E63.8 Other specified nutritional deficiencies
0.000 0.559 0.441
E63.1 Imbalance of constituents of food intake
0.000 0.559 0.441
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.559 0.441
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.559 0.441
E64.8 Sequelae of other nutritional deficiencies
0.000 0.559 0.441
E64.3 Sequelae of rickets
0.000 0.559 0.441
E64.2 Sequelae of vitamin C deficiency
0.000 0.559 0.441
E64.1 Sequelae of vitamin A deficiency
0.000 0.559 0.441
E64.0 Sequelae of protein-energy malnutrition
0.000 0.559 0.441
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.562 0.438
M13 Other arthritis
0.000 0.562 0.438
D61 Other aplastic anaemias
0.000 0.562 0.438
E11.5 With peripheral circulatory complications
0.000 0.563 0.437
J98.3 Compensatory emphysema
0.000 0.563 0.436
H57.1 Ocular pain
0.000 0.564 0.436
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.566 0.434
E29.1 Testicular hypofunction
0.000 0.566 0.434
E53.1 Pyridoxine deficiency
0.000 0.567 0.433
E53.0 Riboflavin deficiency
0.000 0.567 0.433
H57.8 Other specified disorders of eye and adnexa
0.000 0.569 0.431
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.570 0.430
D69.5 Secondary thrombocytopenia
0.000 0.571 0.429
E56.9 Vitamin deficiency, unspecified
0.000 0.572 0.428
E56.8 Deficiency of other vitamins
0.000 0.572 0.428

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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