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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28583512
log Bayes Factor = 6.97733
Chromosome 4   position 20,124,487  (GRCh37) Explore rs28583512 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z86 Personal history of certain other diseases
1.000 0.000 0.000
E11.9 Without complications
0.999 0.001 0.000
Z86.7 Personal history of diseases of the circulatory system
0.999 0.001 0.000
Z86.4 Personal history of psychoactive substance abuse
0.999 0.001 0.000
E11 Non-insulin-dependent diabetes mellitus
0.999 0.001 0.000
Z86.0 Personal history of other neoplasms
0.998 0.002 0.000
E10-E14 Diabetes mellitus
0.979 0.021 0.000
E14 Unspecified diabetes mellitus
0.947 0.053 0.000
E11.4 With neurological complications
0.940 0.060 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.938 0.062 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.934 0.066 0.000
E00-E07 Disorders of thyroid gland
0.933 0.067 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.928 0.072 0.000
E11.2 With renal complications
0.906 0.094 0.000
E05.9 Thyrotoxicosis, unspecified
0.898 0.102 0.000
E11.0 With coma
0.895 0.105 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.872 0.128 0.000
E06 Thyroiditis
0.871 0.129 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.870 0.130 0.000
E14.4 With neurological complications
0.814 0.185 0.000
E14.3 With ophthalmic complications
0.790 0.210 0.000
E14.9 Without complications
0.790 0.210 0.000
E06.3 Autoimmune thyroiditis
0.786 0.214 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.784 0.216 0.000
E14.6 With other specified complications
0.754 0.246 0.000
E50-E64 Other nutritional deficiencies
0.754 0.246 0.000
E11.3 With ophthalmic complications
0.744 0.256 0.000
E11.8 With unspecified complications
0.743 0.257 0.000
E06.9 Thyroiditis, unspecified
0.740 0.260 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.733 0.267 0.000
J84 Other interstitial pulmonary diseases
0.732 0.268 0.000
E65-E68 Obesity and other hyperalimentation
0.728 0.272 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.727 0.273 0.000
E14.2 Withrenal complications
0.726 0.274 0.000
E14.1 With ketoacidosis
0.717 0.283 0.000
E11.7 With multiple complications
0.716 0.284 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.713 0.287 0.000
E12 Malnutrition-related diabetes mellitus
0.702 0.298 0.000
E11.1 With ketoacidosis
0.695 0.305 0.000
E11.5 With peripheral circulatory complications
0.686 0.314 0.000
E14.8 With unspecified complications
0.679 0.321 0.000
E14.7 With multiple complications
0.679 0.321 0.000
E14.5 With peripheral circulatory complications
0.679 0.321 0.000
E14.0 With coma
0.679 0.321 0.000
E61 Deficiency of other nutrient elements
0.678 0.322 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.672 0.328 0.000
E05.5 Thyroid crisis or storm
0.670 0.330 0.000
E05.4 Thyrotoxicosis factitia
0.670 0.330 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.670 0.330 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.670 0.330 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.669 0.331 0.000
E00 Congenital iodine-deficiency syndrome
0.669 0.331 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.669 0.331 0.000
Chapter XX External causes of morbidity and mortality
0.668 0.332 0.000
# Top node
0.662 0.338 0.000
E13 Other specified diabetes mellitus
0.660 0.340 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.651 0.349 0.000
E05.8 Other thyrotoxicosis
0.649 0.351 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.644 0.356 0.000
Chapter X Diseases of the respiratory system
0.644 0.356 0.000
E06.5 Other chronic thyroiditis
0.624 0.376 0.000
E06.4 Drug-induced thyroiditis
0.624 0.376 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.624 0.376 0.000
E06.1 Subacute thyroiditis
0.624 0.376 0.000
E06.0 Acute thyroiditis
0.624 0.376 0.000
Chapter V Mental and behavioural disorders
0.623 0.377 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.619 0.381 0.000
E11.6 With other specified complications
0.618 0.382 0.000
W20-W49 Exposure to inanimate mechanical forces
0.618 0.382 0.000
E61.1 Iron deficiency
0.614 0.386 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.611 0.389 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.607 0.393 0.000
Chapter II Neoplasms
0.598 0.402 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.598 0.402 0.000
X60-X84 Intentional self-harm
0.598 0.402 0.000
E65 Localised adiposity
0.593 0.407 0.000
F30-F39 Mood [affective] disorders
0.593 0.407 0.000
C79 Secondary malignant neoplasm of other sites
0.593 0.407 0.000
Y95 Nosocomial condition
0.592 0.408 0.000
Q80-Q89 Other congenital malformations
0.591 0.409 0.000
F31 Bipolar affective disorder
0.585 0.415 0.000
J60-J70 Lung diseases due to external agents
0.584 0.416 0.000
Chapter XXII Codes for special purposes
0.583 0.417 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.580 0.420 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.578 0.422 0.000
C34 Malignant neoplasm of bronchus and lung
0.574 0.426 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.571 0.429 0.000
E40-E46 Malnutrition
0.570 0.430 0.000
C15-C26 Malignant neoplasms of digestive organs
0.569 0.431 0.000
C20 Malignant neoplasm of rectum
0.569 0.431 0.000
E51 Thiamine deficiency
0.568 0.432 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.563 0.437 0.000
Y00-Y09 Assault
0.563 0.437 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.559 0.441 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.559 0.441 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.557 0.443 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.555 0.445 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.554 0.446 0.000
Chapter VIII Diseases of the ear and mastoid process
0.553 0.447 0.000
E16 Other disorders of pancreatic internal secretion
0.551 0.449 0.000
S20-S29 Injuries to the thorax
0.551 0.449 0.000
W50-W64 Exposure to animate mechanical forces
0.547 0.453 0.000
Q85 Phakomatoses, not elsewhere classified
0.546 0.454 0.000
W44 Foreign body entering into or through eye or natural orifice
0.544 0.456 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.544 0.456 0.000
J90-J94 Other diseases of pleura
0.543 0.457 0.000
C34.9 Bronchus or lung, unspecified
0.543 0.457 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.541 0.459 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.541 0.459 0.000
E63 Other nutritional deficiencies
0.541 0.459 0.000
E56 Other vitamin deficiencies
0.541 0.459 0.000
E50 Vitamin A deficiency
0.541 0.459 0.000
E60 Dietary zinc deficiency
0.541 0.459 0.000
E59 Dietary selenium deficiency
0.541 0.459 0.000
E58 Dietary calcium deficiency
0.541 0.459 0.000
E54 Ascorbic acid deficiency
0.541 0.459 0.000
E52 Niacin deficiency [pellagra]
0.541 0.459 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.540 0.460 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.536 0.464 0.000
H90-H95 Other disorders of ear
0.535 0.465 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.532 0.468 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.532 0.468 0.000
X20-X29 Contact with venomous animals and plants
0.530 0.470 0.000
J84.8 Other specified interstitial pulmonary diseases
0.529 0.471 0.000
J84.0 Alveolar and parietoalveolar conditions
0.525 0.475 0.000
Q00-Q07 Congenital malformations of the nervous system
0.522 0.478 0.000
E67 Other hyperalimentation
0.522 0.478 0.000
E68 Sequelae of hyperalimentation
0.522 0.478 0.000
S27 Injury of other and unspecified intrathoracic organs
0.522 0.478 0.000
Q74 Other congenital malformations of limb(s)
0.521 0.479 0.000
X50-X57 Overexertion, travel and privation
0.518 0.482 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.517 0.483 0.000
X00-X09 Exposure to smoke, fire and flames
0.517 0.483 0.000
E61.2 Magnesium deficiency
0.516 0.484 0.000
V98-V99 Other and unspecified transport accidents
0.513 0.487 0.000
W75-W84 Other accidental threats to breathing
0.513 0.487 0.000
E15 Nondiabetic hypoglycaemic coma
0.511 0.489 0.000
Y10-Y34 Event of undetermined intent
0.510 0.490 0.000
F31.9 Bipolar affective disorder, unspecified
0.510 0.490 0.000
F20 Schizophrenia
0.508 0.492 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.508 0.492 0.000
J91 Pleural effusion in conditions classified elsewhere
0.508 0.492 0.000
F60-F69 Disorders of adult personality and behaviour
0.507 0.493 0.000
T90 Sequelae of injuries of head
0.506 0.494 0.000
H91 Other hearing loss
0.504 0.496 0.000
E12.9 Without complications
0.503 0.496 0.000
E12.8 With unspecified complications
0.503 0.496 0.000
E12.7 With multiple complications
0.503 0.496 0.000
E12.6 With other specified complications
0.503 0.496 0.000
E12.5 With peripheral circulatory complications
0.503 0.496 0.000
E12.4 With neurological complications
0.503 0.496 0.000
E12.3 With ophthalmic complications
0.503 0.496 0.000
E12.2 With renal complications
0.503 0.496 0.000
E12.1 With ketoacidosis
0.503 0.496 0.000
E12.0 With coma
0.503 0.496 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.504 0.496 0.000
W20 Struck by thrown, projected or falling object
0.502 0.498 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.502 0.498 0.000
C15 Malignant neoplasm of oesophagus
0.501 0.499 0.000
Q85.0 Neurofibromatosis (nonmalignant)
0.499 0.501 0.000
E07 Other disorders of thyroid
0.499 0.501 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.499 0.501 0.000
E66 Obesity
0.497 0.503 0.000
C34.1 Upper lobe, bronchus or lung
0.496 0.504 0.000
C34.3 Lower lobe, bronchus or lung
0.494 0.506 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.493 0.507 0.000
C78.7 Secondary malignant neoplasm of liver
0.492 0.508 0.000
V10-V19 Pedal cyclist injured in transport accident
0.492 0.508 0.000
W44.0 Home
0.492 0.508 0.000
J93 Pneumothorax
0.491 0.509 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.491 0.509 0.000
C78.0 Secondary malignant neoplasm of lung
0.490 0.510 0.000
T51 Toxic effect of alcohol
0.488 0.512 0.000
E61.9 Deficiency of nutrient element, unspecified
0.486 0.513 0.000
E61.8 Deficiency of other specified nutrient elements
0.486 0.513 0.000
E61.7 Deficiency of multiple nutrient elements
0.486 0.513 0.000
E61.6 Vanadium deficiency
0.486 0.513 0.000
E61.5 Molybdenum deficiency
0.486 0.513 0.000
E61.4 Chromium deficiency
0.486 0.513 0.000
E61.3 Manganese deficiency
0.486 0.513 0.000
E61.0 Copper deficiency
0.486 0.513 0.000
Q66 Congenital deformities of feet
0.486 0.514 0.000
H90 Conductive and sensorineural hearing loss
0.486 0.514 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.485 0.514 0.000
V01-V09 Pedestrian injured in transport accident
0.482 0.518 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.482 0.518 0.000
H91.9 Hearing loss, unspecified
0.482 0.518 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.481 0.519 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.480 0.520 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.480 0.520 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.480 0.520 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.480 0.520 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.480 0.520 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.480 0.520 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.480 0.520 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.480 0.520 0.000
X45 Accidental poisoning by and exposure to alcohol
0.480 0.520 0.000
Y35-Y36 Legal intervention and operations of war
0.479 0.521 0.000
X85-X99 Assault
0.479 0.521 0.000
X30-X39 Exposure to forces of nature
0.479 0.521 0.000
W65-W74 Accidental drowning and submersion
0.479 0.521 0.000
V95-V97 Air and space transport accidents
0.479 0.521 0.000
V90-V94 Water transport accidents
0.479 0.521 0.000
V70-V79 Bus occupant injured in transport accident
0.479 0.521 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.479 0.521 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.479 0.521 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.479 0.521 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.478 0.522 0.000
S27.0 Traumatic pneumothorax
0.477 0.523 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.476 0.524 0.000
W26 Contact with knife, sword or dagger
0.476 0.524 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.475 0.525 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.475 0.525 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.474 0.526 0.000
E53 Deficiency of other B group vitamins
0.474 0.526 0.000
D00-D09 In situ neoplasms
0.474 0.526 0.000
E13.8 With unspecified complications
0.473 0.527 0.000
E13.7 With multiple complications
0.473 0.527 0.000
E13.6 With other specified complications
0.473 0.527 0.000
E13.5 With peripheral circulatory complications
0.473 0.527 0.000
E13.4 With neurological complications
0.473 0.527 0.000
E13.3 With ophthalmic complications
0.473 0.527 0.000
E13.2 With renal complications
0.473 0.527 0.000
E13.1 With ketoacidosis
0.473 0.527 0.000
E13.0 With coma
0.473 0.527 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.473 0.527 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.472 0.528 0.000
T91 Sequelae of injuries of neck and trunk
0.472 0.528 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.471 0.529 0.000
J95-J99 Other diseases of the respiratory system
0.471 0.529 0.000
F80-F89 Disorders of psychological development
0.471 0.529 0.000
V40-V49 Car occupant injured in transport accident
0.471 0.529 0.000
J64 Unspecified pneumoconiosis
0.468 0.532 0.000
Q65 Congenital deformities of hip
0.468 0.532 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.468 0.532 0.000
W22 Striking against or struck by other objects
0.468 0.532 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.467 0.533 0.000
Q76 Congenital malformations of spine and bony thorax
0.466 0.533 0.000
D06 Carcinoma in situ of cervix uteri
0.466 0.534 0.000
J70 Respiratory conditions due to other external agents
0.466 0.534 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.466 0.534 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.464 0.536 0.000
X58 Exposure to other specified factors
0.464 0.536 0.000
S90-S99 Injuries to the ankle and foot
0.464 0.536 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.464 0.536 0.000
J62 Pneumoconiosis due to dust containing silica
0.464 0.536 0.000
F31.8 Other bipolar affective disorders
0.463 0.537 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.462 0.538 0.000
Q35-Q37 Cleft lip and cleft palate
0.462 0.538 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.462 0.538 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.462 0.538 0.000
D06.9 Cervix, unspecified
0.462 0.538 0.000
T51.9 Alcohol, unspecified
0.461 0.539 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.461 0.539 0.000
T17 Foreign body in respiratory tract
0.460 0.540 0.000
S50-S59 Injuries to the elbow and forearm
0.460 0.540 0.000
Q89 Other congenital malformations, not elsewhere classified
0.459 0.541 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.459 0.541 0.000
U80 Agent resistant to penicillin and related antibiotics
0.459 0.541 0.000
Y00 Assault by blunt object
0.458 0.542 0.000
C43 Malignant melanoma of skin
0.457 0.543 0.000
C80 Malignant neoplasm without specification of site
0.456 0.543 0.000
J60 Coalworker's pneumoconiosis
0.456 0.544 0.000
C34.0 Main bronchus
0.454 0.546 0.000
W21 Striking against or struck by sports equipment
0.453 0.547 0.000
F39 Unspecified mood [affective] disorder
0.453 0.547 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.452 0.548 0.000
E66.9 Obesity, unspecified
0.451 0.549 0.000
E16.1 Other hypoglycaemia
0.451 0.549 0.000
W45 Foreign body or object entering through skin
0.450 0.550 0.000
Q43 Other congenital malformations of intestine
0.450 0.550 0.000
X65 Intentional self-poisoning by and exposure to alcohol
0.450 0.550 0.000
W51 Striking against or bumped into by another person
0.450 0.550 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.450 0.550 0.000
F20.9 Schizophrenia, unspecified
0.449 0.551 0.000
Y04 Assault by bodily force
0.449 0.551 0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents
0.448 0.552 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.447 0.553 0.000
F33 Recurrent depressive disorder
0.447 0.553 0.000
W27 Contact with nonpowered hand tool
0.446 0.554 0.000
H92 Otalgia and effusion of ear
0.446 0.554 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.446 0.554 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.445 0.555 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.445 0.555 0.000
V20-V29 Motorcycle rider injured in transport accident
0.444 0.556 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.443 0.556 0.000
Y98 Lifestyle-related condition
0.443 0.556 0.000
Y97 Environmental-pollution-related condition
0.443 0.556 0.000
Y96 Work-related condition
0.443 0.556 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.443 0.556 0.000
W46 Contact with hypodermic needle
0.443 0.557 0.000
W43 Exposure to vibration
0.443 0.557 0.000
W42 Exposure to noise
0.443 0.557 0.000
W41 Exposure to high-pressure jet
0.443 0.557 0.000
W40 Explosion of other materials
0.443 0.557 0.000
W39 Discharge of firework
0.443 0.557 0.000
W38 Explosion and rupture of other specified pressurised devices
0.443 0.557 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.443 0.557 0.000
W36 Explosion and rupture of gas cylinder
0.443 0.557 0.000
W35 Explosion and rupture of boiler
0.443 0.557 0.000
W34 Discharge from other and unspecified firearms
0.443 0.557 0.000
W33 Rifle, shotgun and larger firearm discharge
0.443 0.557 0.000
W32 Handgun discharge
0.443 0.557 0.000
W31 Contact with other and unspecified machinery
0.443 0.557 0.000
W30 Contact with agricultural machinery
0.443 0.557 0.000
W28 Contact with powered lawn mower
0.443 0.557 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.443 0.557 0.000
Q07 Other congenital malformations of nervous system
0.442 0.558 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.442 0.558 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.441 0.559 0.000
S56 Injury of muscle and tendon at forearm level
0.440 0.560 0.000
C15.4 Middle third of oesophagus
0.439 0.561 0.000
C34.2 Middle lobe, bronchus or lung
0.439 0.561 0.000
Y85 Sequelae of transport accidents
0.439 0.561 0.000
H90.3 Sensorineural hearing loss, bilateral
0.439 0.561 0.000
Y71 Cardiovascular devices associated with adverse incidents
0.439 0.561 0.000
S20 Superficial injury of thorax
0.439 0.561 0.000
X10-X19 Contact with heat and hot substances
0.439 0.561 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.439 0.561 0.000
J93.1 Other spontaneous pneumothorax
0.439 0.561 0.000
Q78 Other osteochondrodysplasias
0.438 0.562 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.438 0.562 0.000
Q75 Other congenital malformations of skull and face bones
0.438 0.562 0.000
Q73 Reduction defects of unspecified limb
0.438 0.562 0.000
Q72 Reduction defects of lower limb
0.438 0.562 0.000
Q71 Reduction defects of upper limb
0.438 0.562 0.000
Q70 Syndactyly
0.438 0.562 0.000
Q69 Polydactyly
0.438 0.562 0.000
Q68 Other congenital musculoskeletal deformities
0.438 0.562 0.000
F29 Unspecified nonorganic psychosis
0.438 0.562 0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents
0.437 0.563 0.000
T58 Toxic effect of carbon monoxide
0.436 0.564 0.000
V80-V89 Other land transport accidents
0.436 0.564 0.000
Q83 Congenital malformations of breast
0.436 0.564 0.000
X48 Accidental poisoning by and exposure to pesticides
0.435 0.565 0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.435 0.565 0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.435 0.565 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.435 0.565 0.000
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.435 0.565 0.000
E51.2 Wernicke's encephalopathy
0.435 0.565 0.000
T63 Toxic effect of contact with venomous animals
0.435 0.565 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.434 0.566 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.433 0.567 0.000
T00-T07 Injuries involving multiple body regions
0.433 0.567 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.433 0.567 0.000
F60 Specific personality disorders
0.433 0.567 0.000
C37 Malignant neoplasm of thymus
0.432 0.568 0.000
E13.9 Without complications
0.431 0.569 0.000
X23 Contact with hornets, wasps and bees
0.431 0.569 0.000
S21 Open wound of thorax
0.430 0.570 0.000
E55 Vitamin D deficiency
0.429 0.571 0.000
F70-F79 Mental retardation
0.429 0.571 0.000
J00-J06 Acute upper respiratory infections
0.429 0.571 0.000
X84 Intentional self-harm by unspecified means
0.429 0.571 0.000
X83 Intentional self-harm by other specified means
0.429 0.571 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.429 0.571 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.429 0.571 0.000
X80 Intentional self-harm by jumping from a high place
0.429 0.571 0.000
X79 Intentional self-harm by blunt object
0.429 0.571 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.429 0.571 0.000
X76 Intentional self-harm by smoke, fire and flames
0.429 0.571 0.000
X75 Intentional self-harm by explosive material
0.429 0.571 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.429 0.571 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.429 0.571 0.000
X72 Intentional self-harm by handgun discharge
0.429 0.571 0.000
X71 Intentional self-harm by drowning and submersion
0.429 0.571 0.000
X70 Intentional self-harm by hanging, strangulation and suffocation
0.429 0.571 0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.429 0.571 0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.429 0.571 0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.429 0.571 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.427 0.572 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.427 0.573 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.427 0.573 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.426 0.574 0.000
F20.0 Paranoid schizophrenia
0.426 0.574 0.000
W20.8 Other specified place
0.426 0.574 0.000
F38 Other mood [affective] disorders
0.425 0.575 0.000
F30 Manic episode
0.425 0.575 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.425 0.575 0.000
J69 Pneumonitis due to solids and liquids
0.425 0.575 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.424 0.576 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.424 0.576 0.000
Q84 Other congenital malformations of integument
0.424 0.576 0.000
Q81 Epidermolysis bullosa
0.424 0.576 0.000
Q80 Congenital ichthyosis
0.424 0.576 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.424 0.576 0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle
0.423 0.577 0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle
0.423 0.577 0.000
Q85.9 Phakomatosis, unspecified
0.423 0.577 0.000
X51 Travel and motion
0.421 0.579 0.000
S27.8 Injury of other specified intrathoracic organs
0.420 0.580 0.000
S10-S19 Injuries to the neck
0.420 0.580 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.420 0.580 0.000
C22.9 Liver, unspecified
0.419 0.581 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.418 0.581 0.000
J66 Airway disease due to specific organic dust
0.418 0.581 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.418 0.581 0.000
J65 Pneumoconiosis associated with tuberculosis
0.418 0.581 0.000
C79.2 Secondary malignant neoplasm of skin
0.418 0.582 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.417 0.582 0.000
T54 Toxic effect of corrosive substances
0.417 0.583 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.416 0.583 0.000
X78 Intentional self-harm by sharp object
0.415 0.585 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.414 0.585 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.414 0.585 0.000
C31 Malignant neoplasm of accessory sinuses
0.414 0.585 0.000
C33 Malignant neoplasm of trachea
0.414 0.585 0.000
Q85.8 Other phakomatoses, not elsewhere classified
0.415 0.585 0.000
Q03 Congenital hydrocephalus
0.413 0.587 0.000
T62 Toxic effect of other noxious substances eaten as food
0.413 0.587 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.413 0.587 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.412 0.587 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.412 0.588 0.000
F80 Specific developmental disorders of speech and language
0.412 0.588 0.000
C34.8 Overlapping lesion of bronchus and lung
0.411 0.588 0.000
F25 Schizoaffective disorders
0.411 0.589 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.411 0.589 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.410 0.590 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.410 0.590 0.000
T33-T35 Frostbite
0.410 0.590 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.410 0.590 0.000
X58.9 Unspecified place
0.410 0.590 0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level
0.410 0.590 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.409 0.591 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.409 0.591 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.408 0.591 0.000
E45 Retarded development following protein-energy malnutrition
0.408 0.591 0.000
E43 Unspecified severe protein-energy malnutrition
0.408 0.591 0.000
E42 Marasmic kwashiorkor
0.408 0.591 0.000
E41 Nutritional marasmus
0.408 0.591 0.000
E40 Kwashiorkor
0.408 0.591 0.000
X49.9 Unspecified place
0.409 0.591 0.000
W94 Exposure to high and low air pressure and changes in air pressure
0.408 0.592 0.000
X00 Exposure to uncontrolled fire in building or structure
0.408 0.592 0.000
T90.1 Sequelae of open wound of head
0.408 0.592 0.000
U51 Admission status on psychiatric patients
0.408 0.592 0.000
T65 Toxic effect of other and unspecified substances
0.408 0.592 0.000
E51.9 Thiamine deficiency, unspecified
0.407 0.592 0.000
E51.8 Other manifestations of thiamine deficiency
0.407 0.592 0.000
E51.1 Beriberi
0.407 0.592 0.000
Q39 Congenital malformations of oesophagus
0.407 0.593 0.000
C15.3 Upper third of oesophagus
0.407 0.593 0.000
Q67.5 Congenital deformity of spine
0.406 0.594 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.405 0.595 0.000
F22 Persistent delusional disorders
0.405 0.595 0.000
X63.0 Home
0.405 0.595 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.404 0.596 0.000
Y09 Assault by unspecified means
0.404 0.596 0.000
Y08 Assault by other specified means
0.404 0.596 0.000
Y07 Other maltreatment syndromes
0.404 0.596 0.000
Y06 Neglect and abandonment
0.404 0.596 0.000
Y05 Sexual assault by bodily force
0.404 0.596 0.000
Y03 Assault by crashing of motor vehicle
0.404 0.596 0.000
Y02 Assault by pushing or placing victim before moving object
0.404 0.596 0.000
Y01 Assault by pushing from high place
0.404 0.596 0.000
T59 Toxic effect of other gases, fumes and vapours
0.403 0.597 0.000
V99 Unspecified transport accident
0.403 0.597 0.000
W79 Inhalation and ingestion of food causing obstruction of respiratory tract
0.402 0.597 0.000
F31.7 Bipolar affective disorder, currently in remission
0.402 0.598 0.000
F99-F99 Unspecified mental disorder
0.402 0.598 0.000
U80.0 Penicillin resistant agent
0.402 0.598 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.401 0.599 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.401 0.599 0.000
Y85.0 Sequelae of motor-vehicle accident
0.400 0.600 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.400 0.600 0.000
Q45 Other congenital malformations of digestive system
0.399 0.601 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.399 0.601 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.399 0.601 0.000
Q40 Other congenital malformations of upper alimentary tract
0.399 0.601 0.000
S27.2 Traumatic heamopneumothorax
0.399 0.601 0.000
E16.2 Hypoglycaemia, unspecified
0.399 0.601 0.000
W25 Contact with sharp glass
0.399 0.601 0.000
F28 Other nonorganic psychotic disorders
0.398 0.602 0.000
F24 Induced delusional disorder
0.398 0.602 0.000
F21 Schizotypal disorder
0.398 0.602 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.398 0.602 0.000
Y28 Contact with sharp object, undetermined intent
0.397 0.603 0.000
Y82 Other and unspecified medical devices associated with adverse incidents
0.397 0.603 0.000
Y81 General- and plastic-surgery devices associated with adverse incidents
0.397 0.603 0.000
Y80 Physical medicine devices associated with adverse incidents
0.397 0.603 0.000
Y78 Radiological devices associated with adverse incidents
0.397 0.603 0.000
Y77 Ophthalmic devices associated with adverse incidents
0.397 0.603 0.000
Y75 Neurological devices associated with adverse incidents
0.397 0.603 0.000
Y74 General hospital and personal-use devices associated with adverse incidents
0.397 0.603 0.000
Y72 Otorhinolaryngological devices associated with adverse incidents
0.397 0.603 0.000
Y70 Anaesthesiology devices associated with adverse incidents
0.397 0.603 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.397 0.603 0.000
C18 Malignant neoplasm of colon
0.396 0.604 0.000
W29 Contact with other powered hand tools and household machinery
0.396 0.604 0.000
C43.9 Malignant melanoma of skin, unspecified
0.395 0.604 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.395 0.605 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.395 0.605 0.000
E16.4 Abnormal secretion of gastrin
0.395 0.605 0.000
E16.3 Increased secretion of glucagon
0.395 0.605 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.395 0.605 0.000
S26 Injury of heart
0.395 0.605 0.000
S25 Injury of blood vessels of thorax
0.395 0.605 0.000
S24 Injury of nerves and spinal cord at thorax level
0.395 0.605 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.395 0.605 0.000
F34 Persistent mood [affective] disorders
0.394 0.606 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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