TreeWAS – Variant ID: rs28602288

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C34.9 Bronchus or lung, unspecified	0.651	0.349	0.000
C34 Malignant neoplasm of bronchus and lung	0.650	0.350	0.000
C34.3 Lower lobe, bronchus or lung	0.603	0.397	0.000
C34.1 Upper lobe, bronchus or lung	0.598	0.402	0.000
C34.0 Main bronchus	0.591	0.409	0.000
C34.2 Middle lobe, bronchus or lung	0.577	0.423	0.000
C34.8 Overlapping lesion of bronchus and lung	0.500	0.500	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.208	0.792	0.000
C33 Malignant neoplasm of trachea	0.163	0.837	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.158	0.842	0.000
C31 Malignant neoplasm of accessory sinuses	0.151	0.849	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.149	0.850	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.143	0.857	0.000
C32 Malignant neoplasm of larynx	0.125	0.874	0.000
C30.0 Nasal cavity	0.122	0.878	0.000
C37 Malignant neoplasm of thymus	0.121	0.879	0.000
C30.1 Middle ear	0.113	0.886	0.000
C31.0 Maxillary sinus	0.109	0.890	0.000
C31.9 Accessory sinus, unspecified	0.108	0.892	0.000
C31.8 Overlapping lesion of accessory sinuses	0.108	0.892	0.000
C31.3 Sphenoidal sinus	0.108	0.892	0.000
C31.2 Frontal sinus	0.108	0.892	0.000
C31.1 Ethmoidal sinus	0.108	0.892	0.000
C39.9 Ill-defined sites within the respiratory system	0.107	0.892	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.107	0.892	0.000
C39.0 Upper respiratory tract, part unspecified	0.107	0.892	0.000
C32.0 Glottis	0.107	0.893	0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.102	0.897	0.000
C38.2 Posterior mediastinum	0.102	0.897	0.000
C38.1 Anterior mediastinum	0.102	0.897	0.000
C38.0 Heart	0.102	0.897	0.000
C38.3 Mediastinum, part unspecified	0.101	0.899	0.000
C38.4 Pleura	0.098	0.902	0.000
C32.8 Overlapping lesion of larynx	0.090	0.910	0.000
C32.2 Subglottis	0.090	0.910	0.000
C32.3 Laryngeal cartilage	0.090	0.910	0.000
J43.9 Emphysema, unspecified	0.089	0.911	0.000
C32.1 Supraglottis	0.068	0.932	0.000
C32.9 Larynx, unspecified	0.057	0.942	0.000
J43 Emphysema	0.054	0.946	0.000
J43.2 Centrilobular emphysema	0.050	0.950	0.000
J43.1 Panlobular emphysema	0.039	0.961	0.000
J43.0 MacLeod's syndrome	0.039	0.961	0.000
J35.1 Hypertrophy of tonsils	0.039	0.961	0.000
J43.8 Other emphysema	0.034	0.966	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.029	0.971	0.000
D12.6 Colon, unspecified	0.024	0.976	0.000
N30.8 Other cystitis	0.000	0.977	0.023
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.023	0.977	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.020	0.980	0.000
D80-D89 Certain disorders involving the immune mechanism	0.020	0.980	0.000
J35 Chronic diseases of tonsils and adenoids	0.018	0.982	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.018	0.982	0.000
D89.3 Immune reconstitution syndrome	0.016	0.983	0.000
J35.2 Hypertrophy of adenoids	0.016	0.984	0.000
D89.1 Cryoglobulinaemia	0.016	0.984	0.000
D83 Common variable immunodeficiency	0.016	0.984	0.000
D82 Immunodeficiency associated with other major defects	0.016	0.984	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.016	0.984	0.000
D55-D59 Haemolytic anaemias	0.016	0.984	0.000
D60-D64 Aplastic and other anaemias	0.015	0.985	0.000
D56 Thalassaemia	0.015	0.985	0.000
D68 Other coagulation defects	0.015	0.985	0.000
D80 Immunodeficiency with predominantly antibody defects	0.015	0.985	0.000
N60.2 Fibroadenosis of breast	0.000	0.985	0.015
D61 Other aplastic anaemias	0.014	0.986	0.000
D81 Combined immunodeficiencies	0.014	0.986	0.000
N30 Cystitis	0.000	0.986	0.014
D56.3 Thalassaemia trait	0.014	0.986	0.000
N30.0 Acute cystitis	0.000	0.986	0.014
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.014	0.986	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.014	0.986	0.000
D68.0 Von Willebrand's disease	0.014	0.986	0.000
J35.0 Chronic tonsillitis	0.014	0.986	0.000
D84 Other immunodeficiencies	0.014	0.986	0.000
N30.1 Interstitial cystitis (chronic)	0.000	0.986	0.014
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.014	0.986	0.000
D61.9 Aplastic anaemia, unspecified	0.014	0.986	0.000
D83.9 Common variable immunodeficiency, unspecified	0.013	0.986	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.013	0.987	0.000
D50-D53 Nutritional anaemias	0.013	0.987	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.013	0.987	0.000
D62 Acute posthaemorrhagic anaemia	0.013	0.987	0.000
D57 Sickle-cell disorders	0.013	0.987	0.000
D61.1 Drug-induced aplastic anaemia	0.013	0.987	0.000
D66 Hereditary factor VIII deficiency	0.012	0.988	0.000
D82.1 Di George's syndrome	0.012	0.988	0.000
D67 Hereditary factor IX deficiency	0.012	0.988	0.000
D52 Folate deficiency anaemia	0.012	0.988	0.000
D68.9 Coagulation defect, unspecified	0.012	0.988	0.000
N60 Benign mammary dysplasia	0.000	0.988	0.012
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.012	0.988	0.000
D68.4 Acquired coagulation factor deficiency	0.012	0.988	0.000
D83.8 Other common variable immunodeficiencies	0.012	0.988	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.012	0.988	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.012	0.988	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.012	0.988	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.012	0.988	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.012	0.988	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.012	0.988	0.000
D82.2 Immunodeficiency with short-limbed stature	0.012	0.988	0.000
D82.0 Wiskott-Aldrich syndrome	0.012	0.988	0.000
N60.0 Solitary cyst of breast	0.000	0.988	0.012
D52.9 Folate deficiency anaemia, unspecified	0.012	0.988	0.000
D56.1 Beta thalassaemia	0.012	0.988	0.000
D55 Anaemia due to enzyme disorders	0.011	0.988	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.011	0.988	0.000
N30.3 Trigonitis	0.000	0.988	0.012
D68.8 Other specified coagulation defects	0.011	0.989	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.011	0.989	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.011	0.989	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.011	0.989	0.000
N60.9 Benign mammary dysplasia, unspecified	0.000	0.989	0.011
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.011	0.989	0.000
D70 Agranulocytosis	0.011	0.989	0.000
D56.9 Thalassaemia, unspecified	0.011	0.989	0.000
D56.8 Other thalassaemias	0.011	0.989	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.011	0.989	0.000
D56.2 Delta-beta thalassaemia	0.011	0.989	0.000
D56.0 Alpha thalassaemia	0.011	0.989	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.011	0.989	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.011	0.989	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.011	0.989	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.011	0.989	0.000
D58 Other hereditary haemolytic anaemias	0.011	0.989	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.011	0.989	0.000
D59 Acquired haemolytic anaemia	0.011	0.989	0.000
D68.1 Hereditary factor XI deficiency	0.011	0.989	0.000
D84.9 Immunodeficiency, unspecified	0.010	0.989	0.000
D61.8 Other specified aplastic anaemias	0.010	0.989	0.000
D61.3 Idiopathic aplastic anaemia	0.010	0.989	0.000
D61.2 Aplastic anaemia due to other external agents	0.010	0.989	0.000
D81.9 Combined immunodeficiency, unspecified	0.010	0.989	0.000
D81.8 Other combined immunodeficiencies	0.010	0.989	0.000
D81.7 Major histocompatibility complex class II deficiency	0.010	0.989	0.000
D81.6 Major histocompatibility complex class I deficiency	0.010	0.989	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.010	0.989	0.000
D81.4 Nezelof's syndrome	0.010	0.989	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.010	0.989	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.010	0.989	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.010	0.989	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.010	0.989	0.000
N60.4 Mammary duct ectasia	0.000	0.989	0.011
D53 Other nutritional anaemias	0.010	0.990	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.010	0.990	0.001
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.010	0.990	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.010	0.990	0.000
D84.8 Other specified immunodeficiencies	0.010	0.990	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.010	0.990	0.000
R25.2 Cramp and spasm	0.000	0.990	0.010
D57.3 Sickle-cell trait	0.010	0.990	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.010	0.990	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.010	0.990	0.000
D57.1 Sickle-cell anaemia without crisis	0.010	0.990	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.010	0.990	0.000
N60.3 Fibrosclerosis of breast	0.000	0.990	0.010
D57.8 Other sickle-cell disorders	0.009	0.991	0.000
D57.2 Double heterozygous sickling disorders	0.009	0.991	0.000
D57.0 Sickle-cell anaemia with crisis	0.009	0.991	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.009	0.991	0.000
D63.0 Anaemia in neoplastic disease	0.009	0.991	0.000
N30.4 Irradiation cystitis	0.000	0.991	0.009
J15.2 Pneumonia due to staphylococcus	0.009	0.991	0.000
D52.8 Other folate deficiency anaemias	0.009	0.991	0.000
D52.1 Drug-induced folate deficiency anaemia	0.009	0.991	0.000
D52.0 Dietary folate deficiency anaemia	0.009	0.991	0.000
D84.1 Defects in the complement system	0.009	0.991	0.000
J15.4 Pneumonia due to other streptococci	0.009	0.991	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.009	0.991	0.000
D86 Sarcoidosis	0.009	0.991	0.000
J15.1 Pneumonia due to Pseudomonas	0.009	0.991	0.000
D51 Vitamin B12 deficiency anaemia	0.009	0.991	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.008	0.991	0.000
D55.8 Other anaemias due to enzyme disorders	0.008	0.991	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.008	0.991	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.008	0.991	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.008	0.991	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.008	0.991	0.000
D53.9 Nutritional anaemia, unspecified	0.008	0.991	0.000
J15.9 Bacterial pneumonia, unspecified	0.008	0.991	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.008	0.992	0.000
D61.0 Constitutional aplastic anaemia	0.008	0.992	0.000
D74 Methaemoglobinaemia	0.008	0.992	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.008	0.992	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.008	0.992	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.008	0.992	0.000
D60.8 Other acquired pure red cell aplasias	0.008	0.992	0.000
D60.1 Transient acquired pure red cell aplasia	0.008	0.992	0.000
D60.0 Chronic acquired pure red cell aplasia	0.008	0.992	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.008	0.992	0.000
D68.5 Primary Thrombophilia	0.008	0.992	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.008	0.992	0.000
D68.2 Hereditary deficiency of other clotting factors	0.008	0.992	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.008	0.992	0.000
D58.1 Hereditary elliptocytosis	0.008	0.992	0.000
J10 Influenza due to identified influenza virus	0.008	0.992	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.008	0.992	0.000
D59.8 Other acquired haemolytic anaemias	0.008	0.992	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.008	0.992	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.008	0.992	0.000
D59.3 Haemolytic-uraemic syndrome	0.008	0.992	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.008	0.992	0.000
D58.2 Other haemoglobinopathies	0.008	0.992	0.000
D75 Other diseases of blood and blood-forming organs	0.008	0.992	0.000
K72.9 Hepatic failure, unspecified	0.008	0.992	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.008	0.992	0.000
D53.8 Other specified nutritional anaemias	0.008	0.992	0.000
D53.2 Scorbutic anaemia	0.008	0.992	0.000
D53.0 Protein deficiency anaemia	0.008	0.992	0.000
D75.1 Secondary polycythaemia	0.008	0.992	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.992	0.008
S72.10 Pertrochanteric fracture (closed)	0.000	0.992	0.008
J09-J18 Influenza and pneumonia	0.008	0.992	0.000
J15.5 Pneumonia due to Escherichia coli	0.008	0.992	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.007	0.993	0.000
N60.8 Other benign mammary dysplasias	0.000	0.993	0.007
J15.3 Pneumonia due to streptococcus, group B	0.007	0.993	0.000
D86.9 Sarcoidosis, unspecified	0.007	0.993	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.007	0.993	0.000
N30.2 Other chronic cystitis	0.000	0.993	0.007
J13 Pneumonia due to Streptococcus pneumoniae	0.007	0.993	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.007	0.993	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.007	0.993	0.000
D58.0 Hereditary spherocytosis	0.007	0.993	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.007	0.993	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.007	0.993	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.007	0.993	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.007	0.993	0.000
J11 Influenza, virus not identified	0.007	0.993	0.000
D51.2 Transcobalamin II deficiency	0.006	0.993	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.006	0.993	0.000
D69 Purpura and other haemorrhagic conditions	0.006	0.993	0.000
J14 Pneumonia due to Haemophilus influenzae	0.006	0.993	0.000
D69.0 Allergic purpura	0.006	0.994	0.000
D74.9 Methaemoglobinaemia, unspecified	0.006	0.994	0.000
D74.8 Other methaemoglobinaemias	0.006	0.994	0.000
D74.0 Congenital methaemoglobinaemia	0.006	0.994	0.000
D64 Other anaemias	0.006	0.994	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.006	0.994	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.006	0.994	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.006	0.994	0.000
J09 Influenza due to certain identified influenza virus	0.006	0.994	0.000
J10.8 Influenza with other manifestations, influenza virus identified	0.006	0.994	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.006	0.994	0.000
J15.8 Other bacterial pneumonia	0.006	0.994	0.000
D68.6 Other Thrombophilia	0.006	0.994	0.000
D76.3 Other histiocytosis syndromes	0.006	0.994	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.006	0.994	0.000
D75.2 Essential thrombocytosis	0.006	0.994	0.000
D72 Other disorders of white blood cells	0.006	0.994	0.000
D69.9 Haemorrhagic condition, unspecified	0.006	0.994	0.000
D86.8 Sarcoidosis of other and combined sites	0.006	0.994	0.000
N28.8 Other specified disorders of kidney and ureter	0.000	0.994	0.006
D59.1 Other autoimmune haemolytic anaemias	0.005	0.994	0.000
K72 Hepatic failure, not elsewhere classified	0.006	0.994	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.006	0.994	0.000
D86.3 Sarcoidosis of skin	0.005	0.994	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.005	0.995	0.000
J11.8 Influenza with other manifestations, virus not identified	0.005	0.995	0.000
C71.9 Brain, unspecified	0.000	0.995	0.005
K72.0 Acute and subacute hepatic failure	0.005	0.995	0.000
D75.0 Familial erythrocytosis	0.005	0.995	0.000
J10.0 Influenza with pneumonia, influenza virus identified	0.005	0.995	0.000
J11.0 Influenza with pneumonia, virus not identified	0.005	0.995	0.000
N60.1 Diffuse cystic mastopathy	0.000	0.995	0.005
H53.8 Other visual disturbances	0.000	0.995	0.005
J11.1 Influenza with other respiratory manifestations, virus not identified	0.005	0.995	0.000
D86.1 Sarcoidosis of lymph nodes	0.005	0.995	0.000
J12 Viral pneumonia, not elsewhere classified	0.005	0.995	0.000
C71.1 Frontal lobe	0.000	0.995	0.005
S92 Fracture of foot, except ankle	0.005	0.995	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.005	0.995	0.000
J16.8 Pneumonia due to other specified infectious organisms	0.005	0.995	0.000
D86.0 Sarcoidosis of lung	0.005	0.995	0.000
S92.1 Fracture of talus	0.005	0.995	0.000
S92.0 Fracture of calcaneus	0.005	0.995	0.000
D64.3 Other sideroblastic anaemias	0.005	0.995	0.000
D64.0 Hereditary sideroblastic anaemia	0.005	0.995	0.000
S92.10 Fracture of talus (closed)	0.005	0.995	0.000
D64.4 Congenital dyserythropoietic anaemia	0.005	0.995	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.005	0.995	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.005	0.995	0.000
D69.2 Other nonthrombocytopenic purpura	0.005	0.995	0.000
K72.1 Chronic hepatic failure	0.005	0.995	0.000
D69.4 Other primary thrombocytopenia	0.005	0.995	0.000
D69.1 Qualitative platelet defects	0.004	0.995	0.000
R25 Abnormal involuntary movements	0.000	0.995	0.005
S92.2 Fracture of other tarsal bone(s)	0.005	0.995	0.000
J16.0 Chlamydial pneumonia	0.004	0.995	0.000
S92.00 Fracture of calcaneus (closed)	0.005	0.995	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.004	0.995	0.000
D03 Melanoma in situ	0.005	0.995	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.004	0.996	0.000
D72.9 Disorder of white blood cells, unspecified	0.004	0.996	0.000
D72.0 Genetic anomalies of leukocytes	0.004	0.996	0.000
D69.8 Other specified haemorrhagic conditions	0.004	0.996	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.004	0.996	0.000
S92.7 Multiple fractures of foot	0.004	0.996	0.000
D64.8 Other specified anaemias	0.004	0.996	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.004	0.996	0.000
E23.0 Hypopituitarism	0.004	0.996	0.000
C71 Malignant neoplasm of brain	0.000	0.996	0.004
K29.1 Other acute gastritis	0.004	0.996	0.000
D50 Iron deficiency anaemia	0.004	0.996	0.000
D72.1 Eosinophilia	0.004	0.996	0.000
S92.5 Fracture of other toe	0.004	0.996	0.000
Z29.2 Other prophylactic chemotherapy	0.000	0.996	0.004
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.996	0.004
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.004	0.996	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.004	0.996	0.000
S92.11 Fracture of talus (open)	0.004	0.996	0.000
S72.1 Pertrochanteric fracture	0.000	0.996	0.004
S92.01 Fracture of calcaneus (open)	0.004	0.996	0.000
C88 Malignant immunoproliferative diseases	0.004	0.996	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.004	0.996	0.000
S92.9 Fracture of foot, unspecified	0.004	0.996	0.000
D03.8 Melanoma in situ of other sites	0.004	0.996	0.000
S92.4 Fracture of great toe	0.004	0.996	0.000
J12.2 Parainfluenza virus pneumonia	0.004	0.996	0.000
J12.8 Other viral pneumonia	0.004	0.996	0.000
J12.3 Human metapneumovirus pneumonia	0.004	0.996	0.000
J12.0 Adenoviral pneumonia	0.004	0.996	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.004	0.996	0.000
C90.2 Plasmacytoma, extramedullary	0.004	0.996	0.000
S92.3 Fracture of metatarsal bone	0.004	0.996	0.000
C71.7 Brain stem	0.000	0.996	0.004
C82.3 Follicular lymphoma grade IIIa	0.004	0.996	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.004	0.996	0.000
S82.30 Fracture of lower end of tibia (closed)	0.000	0.996	0.004
T21 Burn and corrosion of trunk	0.004	0.996	0.000
S92.70 Multiple fractures of foot (closed)	0.004	0.996	0.000
D03.0 Melanoma in situ of lip	0.004	0.996	0.000
T21.2 Burn of second degree of trunk	0.004	0.996	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.004	0.996	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.004	0.996	0.000
J12.1 Respiratory syncytial virus pneumonia	0.003	0.996	0.000
S92.71 Multiple fractures of foot (open)	0.003	0.996	0.000
C71.4 Occipital lobe	0.000	0.996	0.004
S92.21 Fracture of other tarsal bone(s) (open)	0.003	0.996	0.000
S92.50 Fracture of other toe (closed)	0.004	0.996	0.000
R25.0 Abnormal head movements	0.000	0.996	0.003
T88.4 Failed or difficult intubation	0.004	0.996	0.000
J12.9 Viral pneumonia, unspecified	0.003	0.996	0.000
D69.5 Secondary thrombocytopenia	0.003	0.996	0.000
J17 Pneumonia in diseases classified elsewhere	0.003	0.996	0.000
C71.8 Overlapping lesion of brain	0.000	0.996	0.003
D03.9 Melanoma in situ, unspecified	0.003	0.996	0.000
T21.3 Burn of third degree of trunk	0.003	0.996	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.003	0.996	0.000
D50.1 Sideropenic dysphagia	0.003	0.997	0.000
R25.1 Tremor, unspecified	0.000	0.997	0.003
T20-T25 Burns and corrosions of external body surface, specified by site	0.003	0.997	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.003	0.997	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
D50.8 Other iron deficiency anaemias	0.003	0.997	0.000
C71.6 Cerebellum	0.000	0.997	0.003
C71.5 Cerebral ventricle	0.000	0.997	0.003
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.003	0.997	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.003	0.997	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.003	0.997	0.000
C82.0 Small cleaved cell, follicular	0.003	0.997	0.000
S92.51 Fracture of other toe (open)	0.003	0.997	0.000
S92.90 Fracture of foot, unspecified (closed)	0.003	0.997	0.000
T21.1 Burn of first degree of trunk	0.003	0.997	0.000
T40.6 Other and unspecified narcotics	0.000	0.997	0.003
T25 Burn and corrosion of ankle and foot	0.003	0.997	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
S92.40 Fracture of great toe (closed)	0.003	0.997	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.003	0.997	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.997	0.003
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
S72.11 Pertrochanteric fracture (open)	0.000	0.997	0.003
C88.9 Malignant immunoproliferative disease, unspecified	0.003	0.997	0.000
C88.7 Other malignant immunoproliferative diseases	0.003	0.997	0.000
C88.3 Immunoproliferative small intestinal disease	0.003	0.997	0.000
C88.2 Gamma heavy chain disease	0.003	0.997	0.000
C88.1 Alpha heavy chain disease	0.003	0.997	0.000
C71.3 Parietal lobe	0.000	0.997	0.003
S92.91 Fracture of foot, unspecified (open)	0.003	0.997	0.000
C90.0 Multiple myeloma	0.003	0.997	0.000
C67.4 Posterior wall of bladder	0.000	0.997	0.003
T20 Burn and corrosion of head and neck	0.003	0.997	0.000
D03.4 Melanoma in situ of scalp and neck	0.003	0.997	0.000
M86.9 Osteomyelitis, unspecified	0.000	0.997	0.003
C82.4 Follicular lymphoma grade IIIb	0.003	0.997	0.000
S92.31 Fracture of metatarsal bone (open)	0.003	0.997	0.000
S92.41 Fracture of great toe (open)	0.003	0.997	0.000
R60.0 Localised oedema	0.003	0.997	0.000
S92.30 Fracture of metatarsal bone (closed)	0.003	0.997	0.000
D03.5 Melanoma in situ of trunk	0.003	0.997	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
T21.7 Corrosion of third degree of trunk	0.003	0.997	0.000
T21.6 Corrosion of second degree of trunk	0.003	0.997	0.000
T21.5 Corrosion of first degree of trunk	0.003	0.997	0.000
T21.4 Corrosion of unspecified degree of trunk	0.003	0.997	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.000	0.997	0.003
T25.0 Burn of unspecified degree of ankle and foot	0.003	0.997	0.000
C82.6 Cutaneous follicle centre lymphoma	0.003	0.997	0.000
C82.5 Diffuse follicle centre lymphoma	0.003	0.997	0.000
T20.0 Burn of unspecified degree of head and neck	0.003	0.997	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.997	0.003
C83 Diffuse non-Hodgkin's lymphoma	0.003	0.997	0.000
J17.1 Pneumonia in viral diseases classified elsewhere	0.003	0.997	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.003	0.997	0.000
T25.3 Burn of third degree of ankle and foot	0.003	0.997	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.003	0.997	0.000
J17.8 Pneumonia in other diseases classified elsewhere	0.003	0.997	0.000
T21.0 Burn of unspecified degree of trunk	0.003	0.997	0.000
D73 Diseases of spleen	0.002	0.997	0.001
D69.6 Thrombocytopenia, unspecified	0.003	0.997	0.000
C90.3 Solitary plasmacytoma	0.003	0.997	0.000
C81 Hodgkin's disease	0.003	0.997	0.000
S42.40 Fracture of lower end of humerus (closed)	0.000	0.997	0.003
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.003	0.997	0.000
R25.3 Fasciculation	0.000	0.997	0.003
C94 Other leukaemias of specified cell type	0.003	0.997	0.000
T25.2 Burn of second degree of ankle and foot	0.003	0.997	0.000
C86 Other specified types of T/NK-cell lymphoma	0.003	0.997	0.000
T20.1 Burn of first degree of head and neck	0.003	0.997	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
T25.7 Corrosion of third degree of ankle and foot	0.002	0.997	0.000
T25.6 Corrosion of second degree of ankle and foot	0.002	0.997	0.000
T25.5 Corrosion of first degree of ankle and foot	0.002	0.997	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.002	0.997	0.000
T25.1 Burn of first degree of ankle and foot	0.002	0.997	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
C81.2 Mixed cellularity	0.003	0.997	0.000
C71.0 Cerebrum, except lobes and ventricles	0.000	0.997	0.002
G53.0 Postzoster neuralgia	0.000	0.997	0.003
M86 Osteomyelitis	0.000	0.997	0.003
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.003	0.997	0.000
M86.93 Osteomyelitis, unspecified (Forearm)	0.000	0.997	0.002
M86.92 Osteomyelitis, unspecified (Upper arm)	0.000	0.997	0.002
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.000	0.997	0.002
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.000	0.997	0.002
T20.7 Corrosion of third degree of head and neck	0.002	0.997	0.000
T20.6 Corrosion of second degree of head and neck	0.002	0.997	0.000
T20.5 Corrosion of first degree of head and neck	0.002	0.997	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.002	0.997	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.002	0.997	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.002	0.997	0.000
J17.2 Pneumonia in mycoses	0.002	0.997	0.000
T40.4 Other synthetic narcotics	0.000	0.997	0.002
C83.5 Lymphoblastic (diffuse)	0.002	0.998	0.000
C84.0 Mycosis fungoides	0.002	0.998	0.000
Q38.7 Pharyngeal pouch	0.002	0.998	0.000
T20.2 Burn of second degree of head and neck	0.002	0.998	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
C82.2 Large cell, follicular	0.002	0.998	0.000
L89.1 Stage II decubitus ulcer	0.002	0.998	0.000
C92 Myeloid leukaemia	0.002	0.998	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.000	0.998	0.002
D37.4 Colon	0.000	0.998	0.002
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.998	0.002
B02.2 Zoster with other nervous system involvement	0.000	0.998	0.002
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.002	0.998	0.000
H60.3 Other infective otitis externa	0.000	0.998	0.002
M86.6 Other chronic osteomyelitis	0.000	0.998	0.002
C93 Monocytic leukaemia	0.002	0.998	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.998	0.002
C83.6 Undifferentiated (diffuse)	0.002	0.998	0.000
C83.4 Immunoblastic (diffuse)	0.002	0.998	0.000
T20.3 Burn of third degree of head and neck	0.002	0.998	0.000
C83.2 Mixed small and large cell (diffuse)	0.002	0.998	0.000
C92.1 Chronic myeloid leukaemia	0.002	0.998	0.000
D73.3 Abscess of spleen	0.002	0.998	0.001
C95 Leukaemia of unspecified cell type	0.002	0.998	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
M90.10 Periostitis in other infectious diseases classified elsewhere (Multiple sites)	0.000	0.998	0.002
C71.2 Temporal lobe	0.000	0.998	0.002
C81.7 Other Hodgkin's disease	0.002	0.998	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.002	0.998	0.000
D73.2 Chronic congestive splenomegaly	0.002	0.998	0.001
G63.2 Diabetic polyneuropathy	0.000	0.998	0.002
M86.4 Chronic osteomyelitis with draining sinus	0.000	0.998	0.002
C83.7 Burkitt's tumour	0.002	0.998	0.000
C90.1 Plasma cell leukaemia	0.002	0.998	0.000
E83.1 Disorders of iron metabolism	0.000	0.998	0.002
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.002	0.998	0.000
C81.3 Lymphocytic depletion	0.002	0.998	0.000
C81.9 Hodgkin's disease, unspecified	0.002	0.998	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.002	0.998	0.000
D73.4 Cyst of spleen	0.002	0.998	0.001
Q38.6 Other congenital malformations of mouth	0.002	0.998	0.000
J17.3 Pneumonia in parasitic diseases	0.002	0.998	0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.002	0.998	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)	0.000	0.998	0.002
C94.7 Other specified leukaemias	0.002	0.998	0.000
C94.5 Acute myelofibrosis	0.002	0.998	0.000
C94.3 Mast cell leukaemia	0.002	0.998	0.000
C94.2 Acute megakaryoblastic leukaemia	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations