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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28645223
log Bayes Factor = 11.5532
Chromosome 18   position 75,587,548  (GRCh37) Explore rs28645223 on Ensembl!
Variant rs28645223 is part of Cluster X0072

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
M50-M54 Other dorsopathies
0.999 0.001 0.000
M54 Dorsalgia
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
J40-J47 Chronic lower respiratory diseases
0.988 0.012 0.000
Chapter XIV Diseases of the genitourinary system
0.983 0.017 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.978 0.022 0.000
E11 Non-insulin-dependent diabetes mellitus
0.977 0.023 0.000
J90-J94 Other diseases of pleura
0.973 0.027 0.000
N40-N51 Diseases of male genital organs
0.973 0.027 0.000
Chapter I Certain infectious and parasitic diseases
0.969 0.031 0.000
M54.9 Dorsalgia, unspecified
0.966 0.034 0.000
J95-J99 Other diseases of the respiratory system
0.964 0.036 0.000
E16 Other disorders of pancreatic internal secretion
0.962 0.038 0.000
J44 Other chronic obstructive pulmonary disease
0.957 0.043 0.000
E10 Insulin-dependent diabetes mellitus
0.956 0.044 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.952 0.048 0.000
E16.2 Hypoglycaemia, unspecified
0.950 0.050 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.949 0.051 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.945 0.055 0.000
M80-M85 Disorders of bone density and structure
0.944 0.056 0.000
Chapter V Mental and behavioural disorders
0.944 0.056 0.000
N48 Other disorders of penis
0.940 0.060 0.000
E50-E64 Other nutritional deficiencies
0.939 0.061 0.000
E11.9 Without complications
0.930 0.070 0.000
N99-N99 Other disorders of the genitourinary system
0.928 0.072 0.000
J43 Emphysema
0.925 0.075 0.000
Chapter VI Diseases of the nervous system
0.924 0.076 0.000
E14 Unspecified diabetes mellitus
0.923 0.077 0.000
M54.4 Lumbago with sciatica
0.923 0.077 0.000
M54.5 Low back pain
0.918 0.082 0.000
E10.9 Without complications
0.916 0.084 0.000
A30-A49 Other bacterial diseases
0.906 0.094 0.000
J90 Pleural effusion, not elsewhere classified
0.903 0.097 0.000
J60-J70 Lung diseases due to external agents
0.902 0.098 0.000
M54.1 Radiculopathy
0.898 0.102 0.000
J98 Other respiratory disorders
0.897 0.103 0.000
E20-E35 Disorders of other endocrine glands
0.897 0.103 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.889 0.111 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.884 0.116 0.000
M84 Disorders of continuity of bone
0.883 0.117 0.000
J43.9 Emphysema, unspecified
0.880 0.120 0.000
S90-S99 Injuries to the ankle and foot
0.876 0.124 0.000
N25-N29 Other disorders of kidney and ureter
0.871 0.129 0.000
M54.2 Cervicalgia
0.869 0.131 0.000
E14.9 Without complications
0.869 0.131 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.869 0.131 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.863 0.137 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.862 0.138 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.861 0.139 0.000
J40 Bronchitis, not specified as acute or chronic
0.858 0.142 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.858 0.142 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.857 0.143 0.000
M86-M90 Other osteopathies
0.855 0.145 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.855 0.145 0.000
J20-J22 Other acute lower respiratory infections
0.854 0.146 0.000
N10-N16 Renal tubulo-interstitial diseases
0.854 0.146 0.000
M45-M49 Spondylopathies
0.852 0.148 0.000
J92 Pleural plaque
0.851 0.149 0.000
N48.6 Balanitis xerotica obliterans
0.850 0.150 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.841 0.159 0.000
E55 Vitamin D deficiency
0.840 0.160 0.000
M54.12 Radiculopathy (Cervical region)
0.839 0.161 0.000
T66-T78 Other and unspecified effects of external causes
0.838 0.162 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.837 0.163 0.000
N43 Hydrocele and spermatocele
0.837 0.163 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.834 0.166 0.000
N41 Inflammatory diseases of prostate
0.834 0.166 0.000
Chapter XX External causes of morbidity and mortality
0.833 0.167 0.000
E11.4 With neurological complications
0.833 0.167 0.000
G90-G99 Other disorders of the nervous system
0.830 0.170 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.829 0.171 0.000
A41 Other septicaemia
0.827 0.173 0.000
J98.1 Pulmonary collapse
0.824 0.176 0.000
S10-S19 Injuries to the neck
0.823 0.177 0.000
M54.3 Sciatica
0.821 0.179 0.000
G40-G47 Episodic and paroxysmal disorders
0.820 0.180 0.000
N50 Other disorders of male genital organs
0.819 0.181 0.000
N48.8 Other specified disorders of penis
0.818 0.182 0.000
E11.3 With ophthalmic complications
0.817 0.183 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.816 0.184 0.000
J93 Pneumothorax
0.816 0.184 0.000
M05-M14 Inflammatory polyarthropathies
0.813 0.187 0.000
S70-S79 Injuries to the hip and thigh
0.811 0.189 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.807 0.193 0.000
M53 Other dorsopathies, not elsewhere classified
0.806 0.194 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.802 0.198 0.000
M48 Other spondylopathies
0.800 0.200 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.799 0.201 0.000
E53 Deficiency of other B group vitamins
0.797 0.203 0.000
E23 Hypofunction and other disorders of pituitary gland
0.792 0.208 0.000
M54.59 Low back pain (Site unspecified)
0.790 0.210 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.788 0.212 0.000
N48.1 Balanoposthitis
0.787 0.213 0.000
J95.8 Other postprocedural respiratory disorders
0.787 0.213 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.785 0.215 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.784 0.216 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.782 0.218 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.781 0.218 0.000
B95-B98 Bacterial, viral and other infectious agents
0.781 0.219 0.000
F80-F89 Disorders of psychological development
0.780 0.220 0.000
E11.1 With ketoacidosis
0.779 0.221 0.000
M80 Osteoporosis with pathological fracture
0.779 0.221 0.000
S40-S49 Injuries to the shoulder and upper arm
0.777 0.223 0.000
M60-M63 Disorders of muscles
0.777 0.223 0.000
J69 Pneumonitis due to solids and liquids
0.776 0.224 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.775 0.225 0.000
D70 Agranulocytosis
0.774 0.226 0.000
S92 Fracture of foot, except ankle
0.774 0.226 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.769 0.230 0.000
E55.9 Vitamin D deficiency, unspecified
0.769 0.231 0.000
Z88.6 Personal history of allergy to analgesic agent
0.768 0.232 0.000
M40-M43 Deforming dorsopathies
0.767 0.232 0.000
E10.5 With peripheral circulatory complications
0.766 0.234 0.000
J98.4 Other disorders of lung
0.766 0.234 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.766 0.234 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.765 0.235 0.000
T79-T79 Certain early complications of trauma
0.764 0.236 0.000
A80-A89 Viral infections of the central nervous system
0.763 0.237 0.000
E10.1 With ketoacidosis
0.762 0.238 0.000
E22 Hyperfunction of pituitary gland
0.761 0.239 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.759 0.240 0.000
F41 Other anxiety disorders
0.758 0.242 0.000
M54.22 Cervicalgia (Cervical region)
0.757 0.243 0.000
J22 Unspecified acute lower respiratory infection
0.757 0.243 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.756 0.244 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.756 0.244 0.000
M48.0 Spinal stenosis
0.755 0.245 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.755 0.245 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.755 0.245 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.753 0.247 0.000
S50-S59 Injuries to the elbow and forearm
0.752 0.248 0.000
G70-G73 Diseases of myoneural junction and muscle
0.751 0.249 0.000
M89 Other disorders of bone
0.748 0.252 0.000
N00-N08 Glomerular diseases
0.747 0.253 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.743 0.257 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.742 0.258 0.000
A41.9 Septicaemia, unspecified
0.742 0.258 0.000
G93 Other disorders of brain
0.741 0.259 0.000
Chapter XXI Factors influencing health status and contact with health services
0.741 0.259 0.000
M82 Osteoporosis in diseases classified elsewhere
0.741 0.259 0.000
F03 Unspecified dementia
0.740 0.260 0.000
N28.1 Cyst of kidney, acquired
0.739 0.260 0.000
N43.3 Hydrocele, unspecified
0.739 0.261 0.000
E13 Other specified diabetes mellitus
0.739 0.261 0.000
B35-B49 Mycoses
0.738 0.262 0.000
M91-M94 Chondropathies
0.737 0.263 0.000
Chapter VII Diseases of the eye and adnexa
0.736 0.264 0.000
M54.57 Low back pain (Lumbosacral region)
0.735 0.264 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.734 0.266 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.733 0.267 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.732 0.268 0.000
T87 Complications peculiar to reattachment and amputation
0.730 0.270 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.728 0.272 0.000
N42 Other disorders of prostate
0.726 0.273 0.000
E10.4 With neurological complications
0.726 0.274 0.000
S00-S09 Injuries to the head
0.726 0.274 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.725 0.275 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.722 0.278 0.000
E61 Deficiency of other nutrient elements
0.722 0.278 0.000
J92.0 Pleural plaque with presence of asbestos
0.721 0.279 0.000
N48.2 Other inflammatory disorders of penis
0.720 0.280 0.000
M84.0 Malunion of fracture
0.720 0.280 0.000
A46 Erysipelas
0.720 0.280 0.000
S72 Fracture of femur
0.720 0.280 0.000
Z88.5 Personal history of allergy to narcotic agent
0.720 0.280 0.000
N99.2 Postprocedural adhesions of vagina
0.719 0.281 0.000
E40-E46 Malnutrition
0.719 0.281 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.719 0.281 0.000
M70-M79 Other soft tissue disorders
0.718 0.282 0.000
B99-B99 Other infectious diseases
0.718 0.282 0.000
T78 Adverse effects, not elsewhere classified
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.717 0.283 0.000
M54.8 Other dorsalgia
0.716 0.284 0.000
M54.6 Pain in thoracic spine
0.716 0.284 0.000
M54.0 Panniculitis affecting regions of neck and back
0.716 0.284 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.716 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
E23.0 Hypopituitarism
0.716 0.284 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
B15-B19 Viral hepatitis
0.715 0.285 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.715 0.285 0.000
M13 Other arthritis
0.714 0.286 0.000
N48.9 Disorder of penis, unspecified
0.714 0.286 0.000
G30-G32 Other degenerative diseases of the nervous system
0.714 0.286 0.000
J94 Other pleural conditions
0.713 0.286 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.713 0.287 0.000
Q60-Q64 Congenital malformations of the urinary system
0.712 0.288 0.000
F30-F39 Mood [affective] disorders
0.711 0.289 0.000
F60-F69 Disorders of adult personality and behaviour
0.710 0.290 0.000
E11.2 With renal complications
0.710 0.290 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.710 0.290 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.709 0.291 0.000
N99.0 Postprocedural renal failure
0.709 0.291 0.000
J41 Simple and mucopurulent chronic bronchitis
0.708 0.291 0.000
J42 Unspecified chronic bronchitis
0.708 0.292 0.000
N50.9 Disorder of male genital organs, unspecified
0.708 0.292 0.000
M54.19 Radiculopathy (Site unspecified)
0.705 0.295 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.704 0.296 0.000
A49 Bacterial infection of unspecified site
0.704 0.296 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.703 0.297 0.000
F41.9 Anxiety disorder, unspecified
0.701 0.299 0.000
F00 Dementia in Alzheimer's disease
0.701 0.299 0.000
M48.06 Spinal stenosis (Lumbar region)
0.701 0.299 0.000
E15 Nondiabetic hypoglycaemic coma
0.701 0.299 0.000
M54.39 Sciatica (Site unspecified)
0.701 0.299 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.701 0.299 0.000
E11.8 With unspecified complications
0.701 0.299 0.000
E11.7 With multiple complications
0.701 0.299 0.000
E11.6 With other specified complications
0.701 0.299 0.000
E11.0 With coma
0.701 0.299 0.000
S20-S29 Injuries to the thorax
0.698 0.302 0.000
T86 Failure and rejection of transplanted organs and tissues
0.698 0.302 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.697 0.303 0.000
N46 Male infertility
0.697 0.303 0.000
N44 Torsion of testis
0.697 0.303 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.696 0.304 0.000
E53.8 Deficiency of other specified B group vitamins
0.695 0.305 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.695 0.305 0.000
M51 Other intervertebral disk disorders
0.695 0.305 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.695 0.305 0.000
B65-B83 Helminthiases
0.695 0.305 0.000
B50-B64 Protozoal diseases
0.695 0.305 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.695 0.305 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.695 0.305 0.000
A75-A79 Rickettsioses
0.695 0.305 0.000
A70-A74 Other diseases caused by chlamydiae
0.695 0.305 0.000
A65-A69 Other spirochaetal diseases
0.695 0.305 0.000
A20-A28 Certain zoonotic bacterial diseases
0.695 0.305 0.000
A15-A19 Tuberculosis
0.695 0.305 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.693 0.307 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.693 0.307 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.693 0.307 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.693 0.307 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.693 0.307 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.693 0.307 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.693 0.307 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.693 0.307 0.000
M54.56 Low back pain (Lumbar region)
0.692 0.308 0.000
J96 Respiratory failure, not elsewhere classified
0.691 0.309 0.000
E28 Ovarian dysfunction
0.690 0.310 0.000
Chapter XXII Codes for special purposes
0.690 0.310 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.689 0.311 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.689 0.311 0.000
E16.4 Abnormal secretion of gastrin
0.689 0.311 0.000
E16.3 Increased secretion of glucagon
0.689 0.311 0.000
E16.1 Other hypoglycaemia
0.689 0.311 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.689 0.311 0.000
J92.9 Pleural plaque without asbestos
0.688 0.312 0.000
S92.3 Fracture of metatarsal bone
0.688 0.312 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.688 0.312 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.687 0.313 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.687 0.313 0.000
J69.0 Pneumonitis due to food and vomit
0.686 0.314 0.000
E10.8 With unspecified complications
0.686 0.314 0.000
E10.7 With multiple complications
0.686 0.314 0.000
E10.6 With other specified complications
0.686 0.314 0.000
E10.2 With renal complications
0.686 0.314 0.000
E10.0 With coma
0.686 0.314 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.685 0.315 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.684 0.316 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.683 0.317 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.683 0.317 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.683 0.317 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.683 0.317 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.683 0.317 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.683 0.317 0.000
T36 Poisoning by systemic antibiotics
0.683 0.317 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.682 0.318 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.682 0.318 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.682 0.318 0.000
F43 Reaction to severe stress, and adjustment disorders
0.679 0.321 0.000
J93.1 Other spontaneous pneumothorax
0.679 0.321 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.677 0.323 0.000
M83 Adult osteomalacia
0.677 0.323 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.677 0.323 0.000
F70-F79 Mental retardation
0.677 0.323 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.677 0.323 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.677 0.323 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.675 0.325 0.000
N48.5 Ulcer of penis
0.674 0.326 0.000
N48.3 Priapism
0.674 0.326 0.000
N48.0 Leukoplakia of penis
0.674 0.326 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.674 0.326 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.673 0.326 0.000
E63 Other nutritional deficiencies
0.673 0.326 0.000
E56 Other vitamin deficiencies
0.673 0.326 0.000
E51 Thiamine deficiency
0.673 0.326 0.000
E50 Vitamin A deficiency
0.673 0.326 0.000
E60 Dietary zinc deficiency
0.673 0.326 0.000
E59 Dietary selenium deficiency
0.673 0.326 0.000
E58 Dietary calcium deficiency
0.673 0.326 0.000
E54 Ascorbic acid deficiency
0.673 0.326 0.000
E52 Niacin deficiency [pellagra]
0.673 0.326 0.000
J47 Bronchiectasis
0.673 0.327 0.000
N50.8 Other specified disorders of male genital organs
0.672 0.328 0.000
Q00-Q07 Congenital malformations of the nervous system
0.672 0.328 0.000
S12 Fracture of neck
0.672 0.328 0.000
M89.9 Disorder of bone, unspecified
0.672 0.328 0.000
T63 Toxic effect of contact with venomous animals
0.671 0.329 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.670 0.330 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.669 0.331 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.668 0.332 0.000
T43.2 Other and unspecified antidepressants
0.667 0.333 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.667 0.333 0.000
M53.2 Spinal instabilities
0.667 0.333 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.666 0.334 0.000
D68 Other coagulation defects
0.666 0.334 0.000
Q80-Q89 Other congenital malformations
0.665 0.335 0.000
M54.29 Cervicalgia-Site unspe
0.665 0.335 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.664 0.335 0.000
M07 Psoriatic and enteropathic arthropathies
0.664 0.336 0.000
E14.3 With ophthalmic complications
0.664 0.336 0.000
S51 Open wound of forearm
0.663 0.337 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.663 0.337 0.000
J43.8 Other emphysema
0.663 0.337 0.000
J43.2 Centrilobular emphysema
0.663 0.337 0.000
J43.1 Panlobular emphysema
0.663 0.337 0.000
J43.0 MacLeod's syndrome
0.663 0.337 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.663 0.337 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.662 0.338 0.000
E14.8 With unspecified complications
0.662 0.338 0.000
E14.7 With multiple complications
0.662 0.338 0.000
E14.6 With other specified complications
0.662 0.338 0.000
E14.5 With peripheral circulatory complications
0.662 0.338 0.000
E14.4 With neurological complications
0.662 0.338 0.000
E14.2 Withrenal complications
0.662 0.338 0.000
E14.1 With ketoacidosis
0.662 0.338 0.000
E14.0 With coma
0.662 0.338 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.662 0.338 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.662 0.338 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.662 0.338 0.000
M54.44 Lumbago with sciatica-Thoracic
0.662 0.338 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.662 0.338 0.000
M54.42 Lumbago with sciatica-Cervical
0.662 0.338 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.662 0.338 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.662 0.338 0.000
N41.1 Chronic prostatitis
0.660 0.340 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.660 0.340 0.000
T81 Complications of procedures, not elsewhere classified
0.660 0.340 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.660 0.340 0.000
M54.55 Low back pain (Thoracolumbar region)
0.658 0.342 0.000
M54.54 Low back pain-Thoracic
0.658 0.342 0.000
M54.53 Low back pain-Cervicothoracic
0.658 0.342 0.000
M54.52 Low back pain-Cervical
0.658 0.342 0.000
M54.51 Low back pain-Occipit-atl-axl
0.658 0.342 0.000
M54.50 Low back pain (Multiple sites in spine)
0.658 0.342 0.000
E65-E68 Obesity and other hyperalimentation
0.658 0.342 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.658 0.342 0.000
T40.4 Other synthetic narcotics
0.657 0.343 0.000
N41.0 Acute prostatitis
0.657 0.343 0.000
M86 Osteomyelitis
0.657 0.343 0.000
M85 Other disorders of bone density and structure
0.656 0.344 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.656 0.344 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.654 0.346 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.653 0.347 0.000
N26 Unspecified contracted kidney
0.653 0.347 0.000
G40 Epilepsy
0.652 0.348 0.000
Q50-Q56 Congenital malformations of genital organs
0.651 0.348 0.000
J91 Pleural effusion in conditions classified elsewhere
0.651 0.349 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.650 0.350 0.000
A48 Other bacterial diseases, not elsewhere classified
0.650 0.350 0.000
A44 Bartonellosis
0.650 0.350 0.000
A43 Nocardiosis
0.650 0.350 0.000
A42 Actinomycosis
0.650 0.350 0.000
A40 Streptococcal septicaemia
0.650 0.350 0.000
A39 Meningococcal infection
0.650 0.350 0.000
A37 Whooping cough
0.650 0.350 0.000
A36 Diphtheria
0.650 0.350 0.000
A32 Listeriosis
0.650 0.350 0.000
A31 Infection due to other mycobacteria
0.650 0.350 0.000
A30 Leprosy [Hansen's disease]
0.650 0.350 0.000
A38 Scarlet fever
0.650 0.350 0.000
A35 Other tetanus
0.650 0.350 0.000
A34 Obstetrical tetanus
0.650 0.350 0.000
A33 Tetanus neonatorum
0.650 0.350 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.649 0.351 0.000
M43 Other deforming dorsopathies
0.649 0.351 0.000
T51 Toxic effect of alcohol
0.649 0.351 0.000
J46 Status asthmaticus
0.648 0.352 0.000
H52 Disorders of refraction and accommodation
0.648 0.352 0.000
S72.1 Pertrochanteric fracture
0.648 0.352 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.647 0.353 0.000
J70 Respiratory conditions due to other external agents
0.647 0.353 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.647 0.353 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.647 0.353 0.000
J66 Airway disease due to specific organic dust
0.647 0.353 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.647 0.353 0.000
J62 Pneumoconiosis due to dust containing silica
0.647 0.353 0.000
J65 Pneumoconiosis associated with tuberculosis
0.647 0.353 0.000
J64 Unspecified pneumoconiosis
0.647 0.353 0.000
J60 Coalworker's pneumoconiosis
0.647 0.353 0.000
S91 Open wound of ankle and foot
0.646 0.353 0.000
F42 Obsessive-compulsive disorder
0.646 0.354 0.000
F99-F99 Unspecified mental disorder
0.646 0.354 0.000
N02 Recurrent and persistent haematuria
0.645 0.355 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.644 0.356 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.644 0.356 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.644 0.356 0.000
M54.14 Radiculopathy (Thoracic region)
0.644 0.356 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.644 0.356 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.644 0.356 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.644 0.356 0.000
M13.9 Arthritis, unspecified
0.644 0.356 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.643 0.357 0.000
J98.9 Respiratory disorder, unspecified
0.643 0.357 0.000
J98.6 Disorders of diaphragm
0.643 0.357 0.000
J98.3 Compensatory emphysema
0.643 0.357 0.000
J98.2 Interstitial emphysema
0.643 0.357 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.643 0.357 0.000
E34 Other endocrine disorders
0.643 0.357 0.000
E32 Diseases of thymus
0.643 0.357 0.000
E31 Polyglandular dysfunction
0.643 0.357 0.000
E30 Disorders of puberty, not elsewhere classified
0.643 0.357 0.000
E29 Testicular dysfunction
0.643 0.357 0.000
E26 Hyperaldosteronism
0.643 0.357 0.000
E25 Adrenogenital disorders
0.643 0.357 0.000
E24 Cushing's syndrome
0.643 0.357 0.000
E20 Hypoparathyroidism
0.643 0.357 0.000
M54.37 Sciatica (Lumbosacral region)
0.643 0.357 0.000
W00-W19 Falls
0.642 0.358 0.000
M50 Cervical disk disorders
0.641 0.359 0.000
Y52 Agents primarily affecting the cardiovascular system
0.641 0.359 0.000
S60-S69 Injuries to the wrist and hand
0.640 0.360 0.000
E27 Other disorders of adrenal gland
0.639 0.361 0.000
V20-V29 Motorcycle rider injured in transport accident
0.639 0.361 0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified
0.637 0.363 0.000
N99.5 Malfunction of external stoma of urinary tract
0.637 0.363 0.000
N99.1 Postprocedural urethral stricture
0.637 0.363 0.000
B02 Zoster [herpes zoster]
0.636 0.364 0.000
G03 Meningitis due to other and unspecified causes
0.635 0.365 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.634 0.366 0.000
Q35-Q37 Cleft lip and cleft palate
0.634 0.366 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.634 0.366 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.634 0.366 0.000
F84 Pervasive developmental disorders
0.633 0.366 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.633 0.366 0.000
M84.9 Disorder of continuity of bone, unspecified
0.633 0.367 0.000
M84.8 Other disorders of continuity of bone
0.633 0.367 0.000
M84.4 Pathological fracture, not elsewhere classified
0.633 0.367 0.000
M84.3 Stress fracture, not elsewhere classified
0.633 0.367 0.000
M84.2 Delayed union of fracture
0.633 0.367 0.000
N30-N39 Other diseases of urinary system
0.633 0.367 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.633 0.367 0.000
M90 Osteopathies in diseases classified elsewhere
0.633 0.367 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.631 0.368 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.630 0.370 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.630 0.370 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.630 0.370 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.628 0.371 0.000
S99 Other and unspecified injuries of ankle and foot
0.628 0.372 0.000
S98 Traumatic amputation of ankle and foot
0.628 0.372 0.000
S97 Crushing injury of ankle and foot
0.628 0.372 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.628 0.372 0.000
S95 Injury of blood vessels at ankle and foot level
0.628 0.372 0.000
S94 Injury of nerves at ankle and foot level
0.628 0.372 0.000
G70 Myasthenia gravis and other myoneural disorders
0.627 0.373 0.000
S92.30 Fracture of metatarsal bone (closed)
0.626 0.374 0.000
S90 Superficial injury of ankle and foot
0.626 0.374 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.626 0.374 0.000
J93.9 Pneumothorax, unspecified
0.626 0.374 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.625 0.375 0.000
N27 Small kidney of unknown cause
0.625 0.375 0.000
N25 Disorders resulting from impaired renal tubular function
0.625 0.375 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.624 0.376 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.624 0.376 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.624 0.376 0.000
X60-X84 Intentional self-harm
0.623 0.376 0.000
H52.2 Astigmatism
0.623 0.377 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.623 0.377 0.000
M54.27 Cervicalgia-Lumbosacral
0.623 0.377 0.000
M54.26 Cervicalgia-Lumbar
0.623 0.377 0.000
M54.25 Cervicalgia-Thoracolumbar
0.623 0.377 0.000
M54.24 Cervicalgia-Thoracic
0.623 0.377 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.623 0.377 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.623 0.377 0.000
M54.20 Cervicalgia-Mult site
0.623 0.377 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.623 0.377 0.000
F02 Dementia in other diseases classified elsewhere
0.623 0.377 0.000
F01 Vascular dementia
0.623 0.377 0.000
F09 Unspecified organic or symptomatic mental disorder
0.623 0.377 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.623 0.377 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.621 0.379 0.000
A00-A09 Intestinal infectious diseases
0.621 0.379 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.621 0.379 0.000
T88.4 Failed or difficult intubation
0.620 0.380 0.000
G93.4 Encephalopathy, unspecified
0.619 0.381 0.000
M45 Ankylosing spondylitis
0.618 0.382 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.618 0.382 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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