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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2867125
log Bayes Factor = 7.17412
Chromosome 2   position 622,827  (GRCh37) Explore rs2867125 on Ensembl!
Variant rs2867125 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E66.9 Obesity, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.001 0.999
E66 Obesity
0.000 0.001 0.999
E11.9 Without complications
0.000 0.001 0.999
E11.4 With neurological complications
0.000 0.005 0.995
E66.8 Other obesity
0.000 0.008 0.992
E65-E68 Obesity and other hyperalimentation
0.000 0.039 0.961
E10-E14 Diabetes mellitus
0.000 0.040 0.960
E11.2 With renal complications
0.000 0.042 0.958
E11.3 With ophthalmic complications
0.000 0.088 0.912
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.089 0.911
E11.5 With peripheral circulatory complications
0.000 0.171 0.829
E65 Localised adiposity
0.000 0.189 0.811
E10 Insulin-dependent diabetes mellitus
0.000 0.197 0.803
E66.0 Obesity due to excess calories
0.000 0.203 0.797
E11.8 With unspecified complications
0.000 0.203 0.797
E14 Unspecified diabetes mellitus
0.000 0.251 0.749
E10.9 Without complications
0.000 0.268 0.732
E11.7 With multiple complications
0.000 0.283 0.716
E66.1 Drug-induced obesity
0.000 0.284 0.716
E67 Other hyperalimentation
0.000 0.311 0.689
E68 Sequelae of hyperalimentation
0.000 0.311 0.689
E12 Malnutrition-related diabetes mellitus
0.000 0.311 0.688
E11.1 With ketoacidosis
0.000 0.338 0.662
E14.3 With ophthalmic complications
0.000 0.340 0.660
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.349 0.651
E11.6 With other specified complications
0.000 0.353 0.647
E50-E64 Other nutritional deficiencies
0.000 0.357 0.643
E10.0 With coma
0.000 0.361 0.639
E10.8 With unspecified complications
0.000 0.362 0.638
E10.4 With neurological complications
0.000 0.366 0.634
E13 Other specified diabetes mellitus
0.000 0.384 0.616
E10.2 With renal complications
0.000 0.393 0.607
E61 Deficiency of other nutrient elements
0.000 0.402 0.598
E11.0 With coma
0.000 0.407 0.593
E10.7 With multiple complications
0.000 0.424 0.576
E61.1 Iron deficiency
0.000 0.433 0.567
E14.8 With unspecified complications
0.000 0.440 0.560
E10.5 With peripheral circulatory complications
0.000 0.441 0.559
E10.6 With other specified complications
0.000 0.450 0.550
E14.7 With multiple complications
0.000 0.463 0.537
E14.6 With other specified complications
0.000 0.463 0.537
E14.5 With peripheral circulatory complications
0.000 0.463 0.537
E14.1 With ketoacidosis
0.000 0.463 0.537
E14.0 With coma
0.000 0.463 0.537
E14.2 Withrenal complications
0.000 0.481 0.519
E40-E46 Malnutrition
0.000 0.503 0.496
E67.8 Other specified hyperalimentation
0.000 0.506 0.494
E67.3 Hypervitaminosis D
0.000 0.506 0.494
E67.2 Megavitamin-B6 syndrome
0.000 0.506 0.494
E67.1 Hypercarotenaemia
0.000 0.506 0.494
E67.0 Hypervitaminosis A
0.000 0.506 0.494
E12.9 Without complications
0.000 0.506 0.494
E12.8 With unspecified complications
0.000 0.506 0.494
E12.7 With multiple complications
0.000 0.506 0.494
E12.6 With other specified complications
0.000 0.506 0.494
E12.5 With peripheral circulatory complications
0.000 0.506 0.494
E12.4 With neurological complications
0.000 0.506 0.494
E12.3 With ophthalmic complications
0.000 0.506 0.494
E12.2 With renal complications
0.000 0.506 0.494
E12.1 With ketoacidosis
0.000 0.506 0.494
E12.0 With coma
0.000 0.506 0.494
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.515 0.485
E14.9 Without complications
0.000 0.528 0.472
E14.4 With neurological complications
0.000 0.538 0.462
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.539 0.461
E63 Other nutritional deficiencies
0.000 0.539 0.461
E56 Other vitamin deficiencies
0.000 0.539 0.461
E50 Vitamin A deficiency
0.000 0.539 0.461
E60 Dietary zinc deficiency
0.000 0.539 0.461
E59 Dietary selenium deficiency
0.000 0.539 0.461
E58 Dietary calcium deficiency
0.000 0.539 0.461
E54 Ascorbic acid deficiency
0.000 0.539 0.461
E52 Niacin deficiency [pellagra]
0.000 0.539 0.461
E13.8 With unspecified complications
0.000 0.558 0.442
E13.7 With multiple complications
0.000 0.558 0.442
E13.6 With other specified complications
0.000 0.558 0.442
E13.5 With peripheral circulatory complications
0.000 0.558 0.442
E13.4 With neurological complications
0.000 0.558 0.442
E13.3 With ophthalmic complications
0.000 0.558 0.442
E13.2 With renal complications
0.000 0.558 0.442
E13.1 With ketoacidosis
0.000 0.558 0.442
E13.0 With coma
0.000 0.558 0.442
E51 Thiamine deficiency
0.000 0.563 0.437
E61.9 Deficiency of nutrient element, unspecified
0.000 0.571 0.429
E61.8 Deficiency of other specified nutrient elements
0.000 0.571 0.429
E61.7 Deficiency of multiple nutrient elements
0.000 0.571 0.429
E61.6 Vanadium deficiency
0.000 0.571 0.429
E61.5 Molybdenum deficiency
0.000 0.571 0.429
E61.4 Chromium deficiency
0.000 0.571 0.429
E61.3 Manganese deficiency
0.000 0.571 0.429
E61.0 Copper deficiency
0.000 0.571 0.429
E61.2 Magnesium deficiency
0.000 0.577 0.423
E10.3 With ophthalmic complications
0.000 0.598 0.402
E13.9 Without complications
0.000 0.631 0.369
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.644 0.356
E45 Retarded development following protein-energy malnutrition
0.000 0.644 0.356
E43 Unspecified severe protein-energy malnutrition
0.000 0.644 0.356
E42 Marasmic kwashiorkor
0.000 0.644 0.356
E41 Nutritional marasmus
0.000 0.644 0.356
E40 Kwashiorkor
0.000 0.644 0.356
E15 Nondiabetic hypoglycaemic coma
0.000 0.652 0.347
E55 Vitamin D deficiency
0.000 0.663 0.337
E50.9 Vitamin A deficiency, unspecified
0.000 0.669 0.330
E50.8 Other manifestations of vitamin A deficiency
0.000 0.669 0.330
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.669 0.330
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.669 0.330
E50.5 Vitamin A deficiency with night blindness
0.000 0.669 0.330
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.669 0.330
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.669 0.330
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.669 0.330
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.669 0.330
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.669 0.330
E56.9 Vitamin deficiency, unspecified
0.000 0.669 0.330
E56.8 Deficiency of other vitamins
0.000 0.669 0.330
E56.1 Deficiency of vitamin K
0.000 0.669 0.330
E56.0 Deficiency of vitamin E
0.000 0.669 0.330
E63.9 Nutritional deficiency, unspecified
0.000 0.669 0.330
E63.8 Other specified nutritional deficiencies
0.000 0.669 0.330
E63.1 Imbalance of constituents of food intake
0.000 0.669 0.330
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.669 0.330
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.669 0.330
E64.8 Sequelae of other nutritional deficiencies
0.000 0.669 0.330
E64.3 Sequelae of rickets
0.000 0.669 0.330
E64.2 Sequelae of vitamin C deficiency
0.000 0.669 0.330
E64.1 Sequelae of vitamin A deficiency
0.000 0.669 0.330
E64.0 Sequelae of protein-energy malnutrition
0.000 0.669 0.330
E51.9 Thiamine deficiency, unspecified
0.000 0.686 0.313
E51.8 Other manifestations of thiamine deficiency
0.000 0.686 0.313
E51.1 Beriberi
0.000 0.686 0.313
E10.1 With ketoacidosis
0.000 0.690 0.310
E51.2 Wernicke's encephalopathy
0.000 0.710 0.290
E44.1 Mild protein-energy malnutrition
0.000 0.744 0.255
E44.0 Moderate protein-energy malnutrition
0.000 0.744 0.255
E55.0 Rickets, active
0.000 0.758 0.242
E53 Deficiency of other B group vitamins
0.001 0.767 0.233
E46 Unspecified protein-energy malnutrition
0.001 0.800 0.199
E16 Other disorders of pancreatic internal secretion
0.000 0.821 0.179
I10 Essential (primary) hypertension
0.000 0.825 0.175
E53.1 Pyridoxine deficiency
0.001 0.833 0.167
E53.0 Riboflavin deficiency
0.001 0.833 0.167
E53.9 Vitamin B deficiency, unspecified
0.001 0.861 0.138
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.871 0.128
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.871 0.128
E16.4 Abnormal secretion of gastrin
0.000 0.871 0.128
E16.3 Increased secretion of glucagon
0.000 0.871 0.128
G56.0 Carpal tunnel syndrome
0.000 0.872 0.128
E16.1 Other hypoglycaemia
0.000 0.877 0.123
E55.9 Vitamin D deficiency, unspecified
0.000 0.882 0.118
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.888 0.112
Z86.4 Personal history of psychoactive substance abuse
0.000 0.917 0.083
I10-I15 Hypertensive diseases
0.000 0.925 0.075
E00-E07 Disorders of thyroid gland
0.000 0.939 0.061
I12 Hypertensive renal disease
0.000 0.941 0.059
I15 Secondary hypertension
0.000 0.942 0.058
J22 Unspecified acute lower respiratory infection
0.000 0.945 0.055
I13 Hypertensive heart and renal disease
0.000 0.946 0.054
I12.9 Hypertensive renal disease without renal failure
0.000 0.949 0.051
I84.6 Residual haemorrhoidal skin tags
0.000 0.949 0.051
I15.1 Hypertension secondary to other renal disorders
0.000 0.954 0.046
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.956 0.044
E00 Congenital iodine-deficiency syndrome
0.000 0.956 0.044
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.956 0.044
I11 Hypertensive heart disease
0.000 0.956 0.044
E07 Other disorders of thyroid
0.000 0.957 0.043
I15.8 Other secondary hypertension
0.000 0.958 0.042
I15.2 Hypertension secondary to endocrine disorders
0.000 0.958 0.042
I15.0 Renovascular hypertension
0.000 0.958 0.042
I15.9 Seconday hypertension, unspecified
0.000 0.959 0.041
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.961 0.039
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.961 0.039
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.961 0.039
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.961 0.039
E07.9 Disorder of thyroid, unspecified
0.000 0.965 0.035
G56 Mononeuropathies of upper limb
0.000 0.967 0.033
I12.0 Hypertensive renal disease with renal failure
0.000 0.968 0.032
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.968 0.032
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.968 0.032
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.968 0.032
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.968 0.032
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.968 0.032
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.968 0.032
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.968 0.032
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.968 0.032
E16.2 Hypoglycaemia, unspecified
0.000 0.968 0.032
E07.1 Dyshormogenetic goitre
0.000 0.969 0.031
E07.0 Hypersecretion of calcitonin
0.000 0.969 0.031
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.969 0.030
E53.8 Deficiency of other specified B group vitamins
0.001 0.972 0.028
E06 Thyroiditis
0.000 0.972 0.027
G56.8 Other mononeuropathies of upper limb
0.000 0.975 0.025
G56.3 Lesion of radial nerve
0.000 0.975 0.025
G56.1 Other lesions of median nerve
0.000 0.976 0.024
G56.9 Mononeuropathy of upper limb, unspecified
0.000 0.976 0.024
E07.8 Other specified disorders of thyroid
0.000 0.976 0.023
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.977 0.022
E20-E35 Disorders of other endocrine glands
0.006 0.978 0.016
G56.4 Causalgia
0.000 0.978 0.022
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.979 0.021
E03 Other hypothyroidism
0.000 0.980 0.020
E06.5 Other chronic thyroiditis
0.000 0.980 0.020
E06.4 Drug-induced thyroiditis
0.000 0.980 0.020
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.980 0.020
E06.1 Subacute thyroiditis
0.000 0.980 0.020
E06.0 Acute thyroiditis
0.000 0.980 0.020
J20-J22 Other acute lower respiratory infections
0.000 0.980 0.020
O48 Prolonged pregnancy
0.018 0.982 0.000
E05.8 Other thyrotoxicosis
0.000 0.983 0.017
E35 Disorders of endocrine glands in diseases classified elsewhere
0.005 0.984 0.012
E32 Diseases of thymus
0.005 0.984 0.012
E31 Polyglandular dysfunction
0.005 0.984 0.012
E30 Disorders of puberty, not elsewhere classified
0.005 0.984 0.012
E34 Other endocrine disorders
0.003 0.984 0.013
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.984 0.016
E20 Hypoparathyroidism
0.004 0.984 0.012
E05.5 Thyroid crisis or storm
0.000 0.984 0.015
E05.4 Thyrotoxicosis factitia
0.000 0.984 0.015
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.984 0.015
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.984 0.015
G45 Transient cerebral ischaemic attacks and related syndromes
0.000 0.985 0.015
E25 Adrenogenital disorders
0.005 0.985 0.010
G45.9 Transient cerebral ischaemic attack, unspecified
0.000 0.985 0.015
G40-G47 Episodic and paroxysmal disorders
0.000 0.985 0.015
E26 Hyperaldosteronism
0.005 0.985 0.011
G43.1 Migraine with aura [classical migraine]
0.000 0.985 0.015
E06.3 Autoimmune thyroiditis
0.000 0.985 0.015
S83.2 Tear of meniscus, current
0.000 0.985 0.015
E03.5 Myxoedema coma
0.000 0.985 0.015
E03.4 Atrophy of thyroid (acquired)
0.000 0.985 0.015
E03.3 Postinfectious hypothyroidism
0.000 0.985 0.015
E03.1 Congenital hypothyroidism without goitre
0.000 0.985 0.015
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.985 0.015
G43 Migraine
0.000 0.985 0.015
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.986 0.014
E29 Testicular dysfunction
0.004 0.986 0.010
G47.3 Sleep apnoea
0.000 0.986 0.014
J21 Acute bronchiolitis
0.000 0.986 0.014
E28 Ovarian dysfunction
0.004 0.986 0.009
Z86.5 Personal history of other mental and behavioural disorders
0.000 0.986 0.014
G47 Sleep disorders
0.000 0.986 0.014
G44 Other headache syndromes
0.000 0.986 0.014
Z86 Personal history of certain other diseases
0.000 0.986 0.014
J20 Acute bronchitis
0.000 0.987 0.013
E06.9 Thyroiditis, unspecified
0.001 0.987 0.013
E23 Hypofunction and other disorders of pituitary gland
0.007 0.987 0.006
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.000 0.987 0.013
K76.8 Other specified diseases of liver
0.013 0.987 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.000 0.987 0.013
G59.0 Diabetic mononeuropathy
0.000 0.987 0.013
E24 Cushing's syndrome
0.006 0.987 0.007
G44.2 Tension-type headache
0.000 0.987 0.013
G43.8 Other migraine
0.000 0.987 0.013
E34.9 Endocrine disorder, unspecified
0.002 0.988 0.011
E03.8 Other specified hypothyroidism
0.000 0.988 0.012
E22 Hyperfunction of pituitary gland
0.004 0.988 0.008
G41 Status epilepticus
0.000 0.988 0.012
E30.9 Disorder of puberty, unspecified
0.003 0.988 0.009
E30.8 Other disorders of puberty
0.003 0.988 0.009
E30.1 Precocious puberty
0.003 0.988 0.009
E30.0 Delayed puberty
0.003 0.988 0.009
E31.9 Polyglandular dysfunction, unspecified
0.003 0.988 0.009
E31.8 Other polyglandular dysfunction
0.003 0.988 0.009
E31.1 Polyglandular hyperfunction
0.003 0.988 0.009
E31.0 Autoimmune polyglandular failure
0.003 0.988 0.009
E32.9 Disease of thymus, unspecified
0.003 0.988 0.009
E32.8 Other diseases of thymus
0.003 0.988 0.009
E32.1 Abscess of thymus
0.003 0.988 0.009
E32.0 Persistent hyperplasia of thymus
0.003 0.988 0.009
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.003 0.988 0.009
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.003 0.988 0.009
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.003 0.988 0.009
E34.5 Androgen resistance syndrome
0.002 0.988 0.009
E34.4 Constitutional tall stature
0.002 0.988 0.009
E34.3 Short stature, not elsewhere classified
0.002 0.988 0.009
E34.2 Ectopic hormone secretion, not elsewhere classified
0.002 0.988 0.009
E34.1 Other hypersecretion of intestinal hormones
0.002 0.988 0.009
E34.0 Carcinoid syndrome
0.002 0.988 0.010
G45.0 Vertebro-basilar artery syndrome
0.000 0.988 0.012
E34.8 Other specified endocrine disorders
0.002 0.988 0.009
E20.8 Other hypoparathyroidism
0.003 0.988 0.008
E20.1 Pseudohypoparathyroidism
0.003 0.988 0.008
E20.0 Idiopathic hypoparathyroidism
0.003 0.988 0.008
G45.3 Amaurosis fugax
0.000 0.988 0.011
G46 Vascular syndromes of brain in cerebrovascular diseases
0.000 0.989 0.011
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.989 0.011
G45.2 Multiple and bilateral precerebral artery syndromes
0.000 0.989 0.011
E25.9 Adrenogenital disorder, unspecified
0.004 0.989 0.007
E25.8 Other adrenogenital disorders
0.004 0.989 0.007
E20.9 Hypoparathyroidism, unspecified
0.003 0.989 0.008
E26.9 Hyperaldosteronism, unspecified
0.003 0.989 0.008
E26.8 Other hyperaldosteronism
0.003 0.989 0.008
E26.1 Secondary hyperaldosteronism
0.003 0.989 0.008
G44.4 Drug-induced headache, not elsewhere classified
0.000 0.989 0.011
G43.0 Migraine without aura [common migraine]
0.000 0.989 0.011
G44.0 Cluster headache syndrome
0.000 0.989 0.011
G35 Multiple sclerosis
0.011 0.989 0.000
G43.3 Complicated migraine
0.000 0.989 0.011
G43.2 Status migrainosus
0.000 0.989 0.011
G45.1 Carotid artery syndrome (hemispheric)
0.000 0.989 0.011
E29.9 Testicular dysfunction, unspecified
0.003 0.989 0.007
E29.8 Other testicular dysfunction
0.003 0.989 0.007
E29.0 Testicular hyperfunction
0.003 0.989 0.007
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.000 0.989 0.010
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.005 0.990 0.006
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.990 0.010
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.990 0.010
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.990 0.010
G47.1 Disorders of excessive somnolence [hypersomnias]
0.000 0.990 0.010
E28.9 Ovarian dysfunction, unspecified
0.003 0.990 0.007
E28.8 Other ovarian dysfunction
0.003 0.990 0.007
E28.1 Androgen excess
0.003 0.990 0.007
E28.0 Oestrogen excess
0.003 0.990 0.007
G47.2 Disorders of the sleep-wake schedule
0.000 0.990 0.010
G44.3 Chronic posttraumatic headache
0.000 0.990 0.010
G44.1 Vascular headache, not elsewhere classified
0.000 0.990 0.010
G45.4 Transient global amnesia
0.000 0.990 0.010
E26.0 Primary hyperaldosteronism
0.004 0.990 0.007
Z50.1 Other physical therapy
0.000 0.990 0.010
J20.7 Acute bronchitis due to echovirus
0.000 0.990 0.010
J20.6 Acute bronchitis due to rhinovirus
0.000 0.990 0.010
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.990 0.010
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.990 0.010
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.990 0.010
J20.2 Acute bronchitis due to streptococcus
0.000 0.990 0.010
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.990 0.010
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.990 0.010
J21.9 Acute bronchiolitis, unspecified
0.000 0.990 0.010
G41.9 Status epilepticus, unspecified
0.000 0.990 0.010
G47.4 Narcolepsy and cataplexy
0.000 0.990 0.010
G59 Mononeuropathy in diseases classified elsewhere
0.000 0.990 0.010
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.005 0.990 0.004
E23.1 Drug-induced hypopituitarism
0.005 0.990 0.004
I85.9 Oesophageal varices without bleeding
0.000 0.990 0.010
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.005 0.990 0.004
E24.8 Other Cushing's syndrome
0.004 0.990 0.005
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.004 0.990 0.005
E24.3 Ectopic ACTH syndrome
0.004 0.990 0.005
E24.1 Nelson's syndrome
0.004 0.990 0.005
J20.9 Acute bronchitis, unspecified
0.000 0.991 0.009
E27 Other disorders of adrenal gland
0.005 0.991 0.005
H54.7 Unspecified visual loss
0.000 0.991 0.009
E23.0 Hypopituitarism
0.008 0.991 0.001
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.991 0.009
E23.7 Disorder of pituitary gland, unspecified
0.005 0.991 0.004
E24.0 Pituitary-dependent Cushing's disease
0.004 0.991 0.005
G41.0 Grand mal status epilepticus
0.000 0.991 0.009
J20.8 Acute bronchitis due to other specified organisms
0.000 0.991 0.009
E23.2 Diabetes insipidus
0.007 0.991 0.002
E23.6 Other disorders of pituitary gland
0.004 0.991 0.005
E22.9 Hyperfunction of pituitary gland, unspecified
0.003 0.991 0.006
E22.8 Other hyperfunction of pituitary gland
0.003 0.991 0.006
G41.8 Other status epilepticus
0.000 0.991 0.009
G41.2 Complex partial status epilepticus
0.000 0.991 0.009
G41.1 Petit mal status epilepticus
0.000 0.991 0.009
E24.2 Drug-induced Cushing's syndrome
0.005 0.991 0.004
G40 Epilepsy
0.000 0.991 0.009
E28.3 Primary ovarian failure
0.004 0.991 0.005
E28.2 Polycystic ovarian syndrome
0.002 0.991 0.007
G46.7 Other lacunar syndromes
0.000 0.991 0.009
G47.8 Other sleep disorders
0.000 0.991 0.009
E29.1 Testicular hypofunction
0.003 0.991 0.006
E24.9 Cushing's syndrome, unspecified
0.004 0.991 0.004
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.000 0.991 0.008
G46.6 Pure sensory lacunar syndrome
0.000 0.991 0.008
G46.5 Pure motor lacunar syndrome
0.000 0.991 0.008
G46.4 Cerebellar stroke syndrome
0.000 0.991 0.008
G46.3 Brain stem stroke syndrome
0.000 0.991 0.008
G46.2 Posterior cerebral artery syndrome
0.000 0.991 0.008
G46.1 Anterior cerebral artery syndrome
0.000 0.991 0.008
G46.0 Middle cerebral artery syndrome
0.000 0.991 0.008
I85 Oesophageal varices
0.000 0.992 0.008
G40.9 Epilepsy, unspecified
0.000 0.992 0.008
I89.0 Lymphoedema, not elsewhere classified
0.000 0.992 0.008
E22.1 Hyperprolactinaemia
0.004 0.992 0.004
E22.0 Acromegaly and pituitary gigantism
0.003 0.992 0.005
G47.9 Sleep disorder, unspecified
0.000 0.992 0.008
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.003 0.992 0.005
I50.0 Congestive heart failure
0.000 0.992 0.008
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.000 0.992 0.008
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.992 0.008
G44.8 Other specified headache syndromes
0.000 0.992 0.007
I80 Phlebitis and thrombophlebitis
0.000 0.992 0.008
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.992 0.008
E70-E90 Metabolic disorders
0.000 0.993 0.007
G50-G59 Nerve, nerve root and plexus disorders
0.000 0.993 0.007
I84.4 External haemorrhoids with other complications
0.000 0.993 0.007
G56.2 Lesion of ulnar nerve
0.000 0.993 0.007
G59.8 Other mononeuropathies in diseases classified elsewhere
0.000 0.993 0.007
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.993 0.007
E21.4 Other specified disorders of parathyroid gland
0.004 0.993 0.003
E21.2 Other hyperparathyroidism
0.004 0.993 0.003
G40.8 Other epilepsy
0.000 0.993 0.007
E27.5 Adrenomedullary hyperfunction
0.003 0.993 0.004
E27.0 Other adrenocortical overactivity
0.003 0.993 0.004
E04 Other non-toxic goitre
0.000 0.993 0.007
E21.5 Disorder of parathyroid gland, unspecified
0.004 0.993 0.003
I84 Haemorrhoids
0.000 0.993 0.007
H54.9 Unspecified visual impairment (binocular)
0.000 0.993 0.007
H54 Blindness and low vision
0.000 0.993 0.007
E27.3 Drug-induced adrenocortical insufficiency
0.003 0.993 0.003
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.000 0.993 0.007
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.004 0.993 0.003
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.000 0.993 0.007
E27.2 Addisonian crisis
0.003 0.993 0.004
G40.4 Other generalised epilepsy and epileptic syndromes
0.000 0.993 0.007
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.000 0.993 0.007
G40.5 Special epileptic syndromes
0.000 0.993 0.007
I85.0 Oesophageal varices with bleeding
0.000 0.993 0.007
E27.9 Disorder of adrenal gland, unspecified
0.004 0.993 0.002
G40.7 Petit mal, unspecified, without grand mal seizures
0.000 0.993 0.006
I82 Other venous embolism and thrombosis
0.000 0.994 0.006
E27.8 Other specified disorders of adrenal gland
0.004 0.994 0.003
N80.9 Endometriosis, unspecified
0.006 0.994 0.000
E85 Amyloidosis
0.000 0.994 0.006
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.994 0.006
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.994 0.006
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.994 0.006
I82.8 Embolism and thrombosis of other specified veins
0.000 0.994 0.006
I89.1 Lymphangitis
0.000 0.994 0.006
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.000 0.994 0.006
S72.10 Pertrochanteric fracture (closed)
0.000 0.994 0.006
C17.9 Small intestine, unspecified
0.006 0.994 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.004 0.994 0.002
E27.1 Primary adrenocortical insufficiency
0.002 0.994 0.003
S83.3 Tear of articular cartilage of knee, current
0.000 0.994 0.006
S83.1 Dislocation of knee
0.000 0.994 0.006
S83.0 Dislocation of patella
0.000 0.994 0.006
E73 Lactose intolerance
0.000 0.994 0.006
E84 Cystic fibrosis
0.000 0.994 0.006
E79 Disorders of purine and pyrimidine metabolism
0.000 0.994 0.006
E77 Disorders of glycoprotein metabolism
0.000 0.994 0.006
E76 Disorders of glycosaminoglycan metabolism
0.000 0.994 0.006
E72 Other disorders of amino-acid metabolism
0.000 0.994 0.006
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.994 0.006
E70 Disorders of aromatic amino-acid metabolism
0.000 0.994 0.006
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.994 0.006
E21.0 Primary hyperparathyroidism
0.005 0.994 0.001
E05.9 Thyrotoxicosis, unspecified
0.000 0.995 0.005
I84.0 Internal thrombosed haemorrhoids
0.000 0.995 0.005
I81 Portal vein thrombosis
0.000 0.995 0.005
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.995 0.005
G52 Disorders of other cranial nerves
0.000 0.995 0.005
E04.8 Other specified non-toxic goitre
0.000 0.995 0.005
S83.7 Injury to multiple structures of knee
0.000 0.995 0.005
I86 Varicose veins of other sites
0.000 0.995 0.005
E85.4 Organ-limited amyloidosis
0.000 0.995 0.005
H54.6 Unqualified visual loss, one eye
0.000 0.995 0.005
H54.5 Low vision, one eye
0.000 0.995 0.005
H54.3 Unqualified visual loss, both eyes
0.000 0.995 0.005
H54.0 Blindness, both eyes
0.000 0.995 0.005
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.000 0.995 0.005
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.995 0.005
E85.9 Amyloidosis, unspecified
0.000 0.995 0.005
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.000 0.995 0.005
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.000 0.995 0.005
E21.3 Hyperparathyroidism, unspecified
0.003 0.995 0.002
E74 Other disorders of carbohydrate metabolism
0.000 0.995 0.005
H54.4 Blindness, one eye
0.000 0.995 0.005
I82.3 Embolism and thrombosis of renal vein
0.000 0.995 0.005
I82.1 Thrombophlebitis migrans
0.000 0.995 0.005
I82.0 Budd-Chiari syndrome
0.000 0.995 0.005
H54.1 Blindness, one eye, low vision, other eye
0.000 0.995 0.005
I86.8 Varicose veins of other specified sites
0.000 0.995 0.005
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.995 0.005
G35-G37 Demyelinating diseases of the central nervous system
0.003 0.995 0.001
G53 Cranial nerve disorders in diseases classified elsewhere
0.000 0.995 0.005
E04.0 Non-toxic diffuse goitre
0.000 0.995 0.005
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.995 0.005
E85.8 Other amyloidosis
0.000 0.995 0.005
E85.3 Secondary systemic amyloidosis
0.000 0.995 0.005
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.995 0.005
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.995 0.005
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.995 0.005
G54 Nerve root and plexus disorders
0.000 0.995 0.005
S83.6 Sprain and strain of other and unspecified parts of knee
0.000 0.995 0.005
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.995 0.005
H54.2 Low vision, both eyes
0.000 0.995 0.004
I88 Nonspecific lymphadenitis
0.000 0.995 0.004
Z50 Care involving use of rehabilitation procedures
0.000 0.996 0.004
E73.9 Lactose intolerance, unspecified
0.000 0.996 0.004
G51 Facial nerve disorders
0.000 0.996 0.004
E73.8 Other lactose intolerance
0.000 0.996 0.004
E73.1 Secondary lactase deficiency
0.000 0.996 0.004
E73.0 Congenital lactase deficiency
0.000 0.996 0.004
H93.1 Tinnitus
0.000 0.996 0.004
I82.2 Embolism and thrombosis of vena cava
0.000 0.996 0.004
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.996 0.004
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.996 0.004
E70.3 Albinism
0.000 0.996 0.004
E70.2 Disorders of tyrosine metabolism
0.000 0.996 0.004
E70.1 Other hyperphenylalaninaemias
0.000 0.996 0.004
E70.0 Classical phenylketonuria
0.000 0.996 0.004
E71.3 Disorders of fatty-acid metabolism
0.000 0.996 0.004
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.996 0.004
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.996 0.004
E71.0 Maple-syrup-urine disease
0.000 0.996 0.004
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.996 0.004
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.996 0.004
E72.5 Disorders of glycine metabolism
0.000 0.996 0.004
E72.4 Disorders of ornithine metabolism
0.000 0.996 0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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