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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28732080
log Bayes Factor = 111.523
Chromosome 6   position 31,001,177  (GRCh37) Explore rs28732080 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 0.999
M07.3 Other psoriatic arthropathies
0.999 0.001 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
J45 Asthma
0.000 0.001 0.999
Chapter II Neoplasms
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
L40-L45 Papulosquamous disorders
0.998 0.002 0.000
J40-J47 Chronic lower respiratory diseases
0.000 0.003 0.997
Chapter XII Diseases of the skin and subcutaneous tissue
0.997 0.003 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.996 0.004 0.000
L40.0 Psoriasis vulgaris
0.995 0.005 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.005 0.995
J33 Nasal polyp
0.000 0.005 0.995
F30-F39 Mood [affective] disorders
0.994 0.006 0.000
J30-J39 Other diseases of upper respiratory tract
0.000 0.007 0.993
J33.0 Polyp of nasal cavity
0.000 0.009 0.991
J47 Bronchiectasis
0.000 0.009 0.991
Chapter I Certain infectious and parasitic diseases
0.990 0.010 0.000
Chapter X Diseases of the respiratory system
0.000 0.011 0.989
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.988 0.012 0.000
B35-B49 Mycoses
0.981 0.019 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.023 0.977
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.976 0.024 0.000
B37 Candidiasis
0.974 0.026 0.000
F32 Depressive episode
0.971 0.029 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.022 0.030 0.948
C79 Secondary malignant neoplasm of other sites
0.963 0.037 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.039 0.961
E10.9 Without complications
0.000 0.042 0.958
E10-E14 Diabetes mellitus
0.010 0.043 0.948
B37.0 Candidal stomatitis
0.955 0.045 0.000
M07 Psoriatic and enteropathic arthropathies
0.953 0.047 0.000
J33.9 Nasal polyp, unspecified
0.000 0.047 0.953
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.051 0.949
J33.8 Other polyp of sinus
0.000 0.057 0.943
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.941 0.059 0.000
F32.9 Depressive episode, unspecified
0.939 0.061 0.000
J30 Vasomotor and allergic rhinitis
0.000 0.065 0.935
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.933 0.067 0.000
S80-S89 Injuries to the knee and lower leg
0.932 0.068 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.921 0.079 0.000
M05-M14 Inflammatory polyarthropathies
0.920 0.080 0.000
J31.0 Chronic rhinitis
0.000 0.081 0.919
D00-D09 In situ neoplasms
0.918 0.082 0.000
T42.4 Benzodiazepines
0.916 0.084 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.900 0.100 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.900 0.100 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.899 0.101 0.000
C64-C68 Malignant neoplasms of urinary tract
0.893 0.107 0.000
F31 Bipolar affective disorder
0.893 0.107 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.893 0.107 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.887 0.113 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.878 0.122 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.876 0.124 0.000
J45.0 Predominantly allergic asthma
0.000 0.126 0.874
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.874 0.126 0.000
L60-L75 Disorders of skin appendages
0.873 0.127 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.873 0.127 0.000
F60-F69 Disorders of adult personality and behaviour
0.872 0.128 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.871 0.129 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.871 0.129 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.868 0.132 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.867 0.133 0.000
E10.4 With neurological complications
0.000 0.134 0.866
E10.3 With ophthalmic complications
0.000 0.135 0.865
D05 Carcinoma in situ of breast
0.862 0.138 0.000
L40.1 Generalised pustular psoriasis
0.859 0.141 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.857 0.143 0.000
B37.3 Candidiasis of vulva and vagina
0.849 0.151 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.848 0.152 0.000
J30.1 Allergic rhinitis due to pollen
0.000 0.156 0.844
C64 Malignant neoplasm of kidney, except renal pelvis
0.843 0.157 0.000
E07 Other disorders of thyroid
0.000 0.162 0.838
S10-S19 Injuries to the neck
0.835 0.165 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.834 0.166 0.000
F33 Recurrent depressive disorder
0.834 0.166 0.000
F30 Manic episode
0.830 0.170 0.000
Chapter VI Diseases of the nervous system
0.830 0.170 0.000
C15-C26 Malignant neoplasms of digestive organs
0.830 0.170 0.000
S80 Superficial injury of lower leg
0.826 0.174 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.823 0.177 0.000
C79.2 Secondary malignant neoplasm of skin
0.819 0.181 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.819 0.181 0.000
S40-S49 Injuries to the shoulder and upper arm
0.817 0.183 0.001
A50-A64 Infections with a predominantly sexual mode of transmission
0.817 0.183 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.817 0.183 0.000
C01 Malignant neoplasm of base of tongue
0.815 0.185 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.812 0.188 0.000
D70 Agranulocytosis
0.811 0.189 0.000
T43.2 Other and unspecified antidepressants
0.810 0.190 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.810 0.190 0.000
T39.1 4-Aminophenol derivatives
0.806 0.194 0.000
L40.8 Other psoriasis
0.803 0.197 0.000
E50-E64 Other nutritional deficiencies
0.009 0.197 0.794
C34 Malignant neoplasm of bronchus and lung
0.803 0.197 0.000
F17.1 Harmful use
0.801 0.199 0.000
F32.0 Mild depressive episode
0.799 0.201 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.798 0.202 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.793 0.207 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.793 0.207 0.000
B37.1 Pulmonary candidiasis
0.792 0.208 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.789 0.211 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.789 0.211 0.000
A30-A49 Other bacterial diseases
0.788 0.212 0.000
J42 Unspecified chronic bronchitis
0.000 0.212 0.788
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.787 0.213 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.786 0.214 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.786 0.214 0.000
S70-S79 Injuries to the hip and thigh
0.785 0.215 0.001
B49 Unspecified mycosis
0.784 0.216 0.000
E10.5 With peripheral circulatory complications
0.000 0.218 0.782
F60 Specific personality disorders
0.782 0.218 0.000
B65-B83 Helminthiases
0.781 0.219 0.000
S82 Fracture of lower leg, including ankle
0.778 0.222 0.000
E10.1 With ketoacidosis
0.000 0.224 0.775
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.774 0.226 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.774 0.226 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.774 0.226 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.772 0.228 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.767 0.233 0.000
J30.3 Other allergic rhinitis
0.000 0.234 0.766
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.765 0.235 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.765 0.235 0.000
B37.4 Candidiasis of other urogenital sites
0.764 0.235 0.000
M86-M90 Other osteopathies
0.764 0.236 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.763 0.237 0.000
B37.9 Candidiasis, unspecified
0.763 0.237 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.761 0.239 0.000
D05.1 Intraductal carcinoma in situ
0.760 0.240 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.759 0.241 0.000
S81 Open wound of lower leg
0.754 0.246 0.000
J36 Peritonsillar abscess
0.000 0.246 0.754
T36 Poisoning by systemic antibiotics
0.752 0.248 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.749 0.251 0.000
J60-J70 Lung diseases due to external agents
0.000 0.253 0.747
E10.2 With renal complications
0.000 0.253 0.746
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.746 0.254 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.254 0.746
A15-A19 Tuberculosis
0.745 0.254 0.000
D06 Carcinoma in situ of cervix uteri
0.745 0.255 0.000
L73 Other follicular disorders
0.744 0.256 0.000
J30.4 Allergic rhinitis, unspecified
0.000 0.257 0.743
B99-B99 Other infectious diseases
0.743 0.257 0.000
B36 Other superficial mycoses
0.742 0.258 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.742 0.258 0.000
G90-G99 Other disorders of the nervous system
0.742 0.258 0.000
D73 Diseases of spleen
0.736 0.264 0.000
F44 Dissociative [conversion] disorders
0.736 0.264 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.736 0.264 0.000
F31.8 Other bipolar affective disorders
0.735 0.265 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.734 0.266 0.000
S41 Open wound of shoulder and upper arm
0.730 0.270 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.730 0.270 0.000
C11 Malignant neoplasm of nasopharynx
0.728 0.272 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.726 0.274 0.000
J32 Chronic sinusitis
0.000 0.274 0.726
C18 Malignant neoplasm of colon
0.726 0.274 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.725 0.274 0.000
J37 Chronic laryngitis and laryngotracheitis
0.000 0.275 0.725
E06 Thyroiditis
0.000 0.275 0.725
C05 Malignant neoplasm of palate
0.724 0.276 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.722 0.278 0.000
B15-B19 Viral hepatitis
0.720 0.280 0.000
G70-G73 Diseases of myoneural junction and muscle
0.718 0.282 0.000
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
M07.38 Other psoriatic arthropathies (Other)
0.717 0.283 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.717 0.283 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.717 0.283 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.717 0.283 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.717 0.283 0.000
T42.1 Iminostilbenes
0.716 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
E05.8 Other thyrotoxicosis
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.716 0.284 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.716 0.284 0.000
J45.8 Mixed asthma
0.000 0.284 0.716
J45.1 Nonallergic asthma
0.000 0.284 0.716
C73 Malignant neoplasm of thyroid gland
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
F34 Persistent mood [affective] disorders
0.715 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
L44 Other papulosquamous disorders
0.715 0.285 0.000
L41 Parapsoriasis
0.715 0.285 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.715 0.285 0.000
L42 Pityriasis rosea
0.715 0.285 0.000
S82.1 Fracture of upper end of tibia
0.715 0.285 0.000
J41 Simple and mucopurulent chronic bronchitis
0.000 0.285 0.715
L10-L14 Bullous disorders
0.715 0.285 0.000
F41 Other anxiety disorders
0.714 0.286 0.000
B25-B34 Other viral diseases
0.714 0.286 0.000
F80-F89 Disorders of psychological development
0.714 0.286 0.000
J33.1 Polypoid sinus degeneration
0.000 0.287 0.713
F38 Other mood [affective] disorders
0.713 0.287 0.000
F39 Unspecified mood [affective] disorder
0.713 0.287 0.000
S79 Other and unspecified injuries of hip and thigh
0.712 0.288 0.001
M91-M94 Chondropathies
0.712 0.288 0.000
C32 Malignant neoplasm of larynx
0.712 0.288 0.000
C18.7 Sigmoid colon
0.711 0.289 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.710 0.290 0.000
B50-B64 Protozoal diseases
0.710 0.290 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.710 0.290 0.000
A75-A79 Rickettsioses
0.710 0.290 0.000
A70-A74 Other diseases caused by chlamydiae
0.710 0.290 0.000
A65-A69 Other spirochaetal diseases
0.710 0.290 0.000
A20-A28 Certain zoonotic bacterial diseases
0.710 0.290 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.709 0.291 0.000
T39.0 Salicylates
0.709 0.291 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.708 0.292 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.708 0.292 0.000
T42.3 Barbiturates
0.708 0.292 0.000
T42.2 Succinimides and oxazolidinediones
0.708 0.292 0.000
T42.0 Hydantoin derivatives
0.708 0.292 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.708 0.292 0.000
C09 Malignant neoplasm of tonsil
0.707 0.292 0.000
L71 Rosacea
0.706 0.294 0.000
M60-M63 Disorders of muscles
0.705 0.295 0.000
Q21 Congenital malformations of cardiac septa
0.705 0.295 0.000
B48 Other mycoses, not elsewhere classified
0.703 0.297 0.000
B47 Mycetoma
0.703 0.297 0.000
B46 Zygomycosis
0.703 0.297 0.000
B45 Cryptococcosis
0.703 0.297 0.000
B43 Chromomycosis and phaeomycotic abscess
0.703 0.297 0.000
B42 Sporotrichosis
0.703 0.297 0.000
B41 Paracoccidioidomycosis
0.703 0.297 0.000
B40 Blastomycosis
0.703 0.297 0.000
B39 Histoplasmosis
0.703 0.297 0.000
B38 Coccidioidomycosis
0.703 0.297 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.703 0.297 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.703 0.297 0.000
M80-M85 Disorders of bone density and structure
0.703 0.297 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.703 0.297 0.000
S80.9 Superficial injury of lower leg, unspecified
0.702 0.298 0.000
T43.6 Psychostimulants with abuse potential
0.702 0.298 0.000
B37.7 Candidal septicaemia
0.698 0.302 0.000
B37.6 Candidal endocarditis
0.698 0.302 0.000
B37.5 Candidal meningitis
0.698 0.302 0.000
B37.2 Candidiasis of skin and nail
0.698 0.302 0.000
C04 Malignant neoplasm of floor of mouth
0.698 0.302 0.000
M50-M54 Other dorsopathies
0.697 0.303 0.000
C34.9 Bronchus or lung, unspecified
0.696 0.304 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.696 0.304 0.000
C79.6 Secondary malignant neoplasm of ovary
0.696 0.304 0.000
F32.8 Other depressive episodes
0.696 0.304 0.000
D72 Other disorders of white blood cells
0.695 0.305 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.694 0.306 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.693 0.307 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.692 0.308 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.691 0.309 0.000
M14 Arthropathies in other diseases classified elsewhere
0.690 0.309 0.000
G93 Other disorders of brain
0.690 0.310 0.000
D07.1 Vulva
0.690 0.310 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.690 0.310 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.689 0.310 0.000
E10.8 With unspecified complications
0.000 0.311 0.689
E10.7 With multiple complications
0.000 0.311 0.689
E10.6 With other specified complications
0.000 0.311 0.689
E10.0 With coma
0.000 0.311 0.689
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.688 0.312 0.000
D55-D59 Haemolytic anaemias
0.688 0.312 0.000
E12 Malnutrition-related diabetes mellitus
0.007 0.314 0.679
F60.3 Emotionally unstable personality disorder
0.686 0.314 0.000
S32 Fracture of lumbar spine and pelvis
0.685 0.315 0.000
A49 Bacterial infection of unspecified site
0.685 0.315 0.000
M07.6 Other enteropathic arthropathies
0.683 0.316 0.000
M07.5 Arthropathy in ulcerative colitis
0.683 0.316 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.683 0.316 0.000
M07.2 Psoriatic spondylitis
0.683 0.316 0.000
M07.1 Arthritis mutilans
0.683 0.316 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.683 0.316 0.000
E03.8 Other specified hypothyroidism
0.000 0.317 0.683
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.682 0.318 0.000
L70 Acne
0.681 0.319 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.681 0.319 0.000
J31.1 Chronic nasopharyngitis
0.000 0.320 0.680
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.679 0.320 0.000
E40-E46 Malnutrition
0.015 0.322 0.663
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.676 0.323 0.001
C20 Malignant neoplasm of rectum
0.676 0.324 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.676 0.324 0.000
F40 Phobic anxiety disorders
0.675 0.325 0.000
G20-G26 Extrapyramidal and movement disorders
0.674 0.326 0.000
S82.10 Fracture of upper end of tibia (closed)
0.670 0.330 0.000
J30.2 Other seasonal allergic rhinitis
0.000 0.330 0.670
J30.0 Vasomotor rhinitis
0.000 0.330 0.670
C34.2 Middle lobe, bronchus or lung
0.669 0.331 0.000
C13 Malignant neoplasm of hypopharynx
0.669 0.331 0.000
C10 Malignant neoplasm of oropharynx
0.669 0.331 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.669 0.331 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.669 0.331 0.000
C03 Malignant neoplasm of gum
0.669 0.331 0.000
C00 Malignant neoplasm of lip
0.669 0.331 0.000
C12 Malignant neoplasm of pyriform sinus
0.669 0.331 0.000
C07 Malignant neoplasm of parotid gland
0.669 0.331 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.669 0.331 0.000
S88 Traumatic amputation of lower leg
0.668 0.332 0.000
S87 Crushing injury of lower leg
0.668 0.332 0.000
S85 Injury of blood vessels at lower leg level
0.668 0.332 0.000
S84 Injury of nerves at lower leg level
0.668 0.332 0.000
F45 Somatoform disorders
0.668 0.332 0.000
S41.1 Open wound of upper arm
0.667 0.333 0.000
F99-F99 Unspecified mental disorder
0.667 0.333 0.000
S14 Injury of nerves and spinal cord at neck level
0.667 0.333 0.000
G61 Inflammatory polyneuropathy
0.666 0.334 0.000
F32.1 Moderate depressive episode
0.666 0.334 0.000
C21 Malignant neoplasm of anus and anal canal
0.666 0.334 0.000
M40-M43 Deforming dorsopathies
0.666 0.334 0.000
A80-A89 Viral infections of the central nervous system
0.664 0.336 0.000
J31.2 Chronic pharyngitis
0.000 0.337 0.663
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.337 0.662
T79-T79 Certain early complications of trauma
0.662 0.338 0.000
S86 Injury of muscle and tendon at lower leg level
0.661 0.339 0.000
M12 Other specific arthropathies
0.660 0.340 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.660 0.340 0.000
M08 Juvenile arthritis
0.660 0.340 0.000
S79.9 Unspecified injury of hip and thigh
0.659 0.340 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.659 0.341 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.658 0.342 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.658 0.342 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.658 0.342 0.000
C66 Malignant neoplasm of ureter
0.657 0.343 0.000
S40 Superficial injury of shoulder and upper arm
0.656 0.343 0.001
S31 Open wound of abdomen, lower back and pelvis
0.657 0.343 0.000
F30.0 Hypomania
0.657 0.343 0.000
C77.1 Intrathoracic lymph nodes
0.657 0.343 0.000
M00-M03 Infectious arthropathies
0.656 0.344 0.000
C77.0 Lymph nodes of head, face and neck
0.656 0.344 0.000
D68 Other coagulation defects
0.655 0.345 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.655 0.345 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.655 0.345 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.654 0.346 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.653 0.347 0.000
E55 Vitamin D deficiency
0.005 0.351 0.644
M84 Disorders of continuity of bone
0.649 0.351 0.000
Q00-Q07 Congenital malformations of the nervous system
0.647 0.353 0.000
C17 Malignant neoplasm of small intestine
0.647 0.353 0.000
M50 Cervical disk disorders
0.646 0.354 0.000
C45 Mesothelioma
0.645 0.355 0.000
T43.9 Psychotropic drug, unspecified
0.645 0.355 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.645 0.355 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.645 0.355 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.645 0.355 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.645 0.355 0.000
C31 Malignant neoplasm of accessory sinuses
0.645 0.355 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.645 0.355 0.000
C37 Malignant neoplasm of thymus
0.645 0.355 0.000
C33 Malignant neoplasm of trachea
0.645 0.355 0.000
J95-J99 Other diseases of the respiratory system
0.000 0.356 0.644
G62 Other polyneuropathies
0.644 0.356 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.642 0.358 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.640 0.359 0.000
D75 Other diseases of blood and blood-forming organs
0.640 0.360 0.000
F31.7 Bipolar affective disorder, currently in remission
0.640 0.360 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.640 0.360 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.640 0.360 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.640 0.360 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.640 0.360 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.640 0.360 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.640 0.360 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.640 0.360 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.640 0.360 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.640 0.360 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.640 0.360 0.000
T44.0 Anticholinesterase agents
0.640 0.360 0.000
S10 Superficial injury of neck
0.640 0.360 0.000
G63.2 Diabetic polyneuropathy
0.639 0.361 0.000
Q21.1 Atrial septal defect
0.639 0.361 0.000
F30.9 Manic episode, unspecified
0.639 0.361 0.000
S36 Injury of intra-abdominal organs
0.639 0.361 0.000
C65 Malignant neoplasm of renal pelvis
0.638 0.361 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.638 0.361 0.000
F33.9 Recurrent depressive disorder, unspecified
0.638 0.362 0.000
F31.9 Bipolar affective disorder, unspecified
0.638 0.362 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.638 0.362 0.000
F41.2 Mixed anxiety and depressive disorder
0.638 0.362 0.000
B00 Herpesviral [herpes simplex] infections
0.637 0.363 0.000
D46 Myelodysplastic syndromes
0.636 0.363 0.000
F30.2 Mania with psychotic symptoms
0.636 0.364 0.000
D73.0 Hyposplenism
0.636 0.364 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.636 0.364 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.635 0.365 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.634 0.366 0.000
E13 Other specified diabetes mellitus
0.007 0.369 0.624
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.631 0.369 0.000
B80 Enterobiasis
0.631 0.369 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.631 0.369 0.000
C76.2 Abdomen
0.630 0.370 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.629 0.370 0.000
Q35-Q37 Cleft lip and cleft palate
0.629 0.370 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.629 0.370 0.000
F48 Other neurotic disorders
0.628 0.372 0.000
S90-S99 Injuries to the ankle and foot
0.627 0.372 0.000
B44 Aspergillosis
0.627 0.373 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.627 0.373 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.627 0.373 0.000
T39.4 Antirheumatics, not elsewhere classified
0.627 0.373 0.000
T39.2 Pyrazolone derivatives
0.627 0.373 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.626 0.374 0.000
L75 Apocrine sweat disorders
0.626 0.374 0.000
L74 Eccrine sweat disorders
0.626 0.374 0.000
L68 Hypertrichosis
0.626 0.374 0.000
L67 Hair colour and hair shaft abnormalities
0.626 0.374 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.626 0.374 0.000
L65 Other nonscarring hair loss
0.626 0.374 0.000
L64 Androgenic alopecia
0.626 0.374 0.000
L63 Alopecia areata
0.626 0.374 0.000
L62 Nail disorders in diseases classified elsewhere
0.626 0.374 0.000
F68 Other disorders of adult personality and behaviour
0.625 0.375 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.625 0.375 0.000
F65 Disorders of sexual preference
0.625 0.375 0.000
F64 Gender identity disorders
0.625 0.375 0.000
F63 Habit and impulse disorders
0.625 0.375 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.625 0.375 0.000
F69 Unspecified disorder of adult personality and behaviour
0.625 0.375 0.000
F61 Mixed and other personality disorders
0.625 0.375 0.000
D74 Methaemoglobinaemia
0.624 0.375 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.624 0.375 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.624 0.375 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.624 0.376 0.000
T38.9 Other and unspecified hormone antagonists
0.622 0.377 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.622 0.377 0.000
T38.7 Androgens and anabolic congeners
0.622 0.377 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.622 0.377 0.000
T38.5 Other oestrogens and progestogens
0.622 0.377 0.000
T38.4 Oral contraceptives
0.622 0.377 0.000
T38.2 Antithyroid drugs
0.622 0.377 0.000
T38.1 Thyroid hormones and substitutes
0.622 0.377 0.000
T38.0 Glucocorticoids and synthetic analogues
0.622 0.377 0.000
D80-D89 Certain disorders involving the immune mechanism
0.622 0.378 0.000
D06.9 Cervix, unspecified
0.621 0.379 0.000
C34.0 Main bronchus
0.621 0.379 0.000
F60.7 Dependent personality disorder
0.621 0.379 0.000
Q50-Q56 Congenital malformations of genital organs
0.621 0.379 0.000
E53 Deficiency of other B group vitamins
0.005 0.380 0.616
M11 Other crystal arthropathies
0.620 0.380 0.000
D05.7 Other carcinoma in situ of breast
0.618 0.382 0.000
G70 Myasthenia gravis and other myoneural disorders
0.618 0.382 0.000
S80.8 Other superficial injuries of lower leg
0.618 0.382 0.000
J69 Pneumonitis due to solids and liquids
0.000 0.383 0.617
S82.6 Fracture of lateral malleolus
0.617 0.383 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.616 0.384 0.000
T66-T78 Other and unspecified effects of external causes
0.616 0.384 0.000
S19 Other and unspecified injuries of neck
0.614 0.385 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.614 0.385 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.614 0.385 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.614 0.385 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.614 0.385 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.614 0.385 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.614 0.385 0.000
G93.3 Postviral fatigue syndrome
0.613 0.387 0.000
F42 Obsessive-compulsive disorder
0.613 0.387 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.613 0.387 0.000
G60 Hereditary and idiopathic neuropathy
0.613 0.387 0.000
S81.8 Open wound of other parts of lower leg
0.612 0.388 0.000
B35 Dermatophytosis
0.611 0.388 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.014 0.388 0.597
Q60-Q64 Congenital malformations of the urinary system
0.611 0.389 0.000
Q80-Q89 Other congenital malformations
0.609 0.390 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.608 0.392 0.000
S37 Injury of urinary and pelvic organs
0.608 0.392 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.608 0.392 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.608 0.392 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.608 0.392 0.000
L73.9 Follicular disorder, unspecified
0.608 0.392 0.000
S82.2 Fracture of shaft of tibia
0.606 0.394 0.000
C32.0 Glottis
0.605 0.395 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.604 0.395 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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