TreeWAS – Variant ID: rs28732082

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
L40.0 Psoriasis vulgaris	0.997	0.003	0.000
E03 Other hypothyroidism	0.000	0.004	0.996
E00-E07 Disorders of thyroid gland	0.000	0.006	0.994
M07.39 Other psoriatic arthropathies (Site unspecified)	0.994	0.006	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.008	0.992
M07.3 Other psoriatic arthropathies	0.991	0.009	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.983	0.017	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.024	0.976
E05.9 Thyrotoxicosis, unspecified	0.000	0.024	0.976
E07 Other disorders of thyroid	0.000	0.119	0.881
M07.34 Other psoriatic arthropathies (Hand)	0.862	0.138	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.859	0.141	0.000
L40.1 Generalised pustular psoriasis	0.833	0.167	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.819	0.181	0.000
L40.8 Other psoriasis	0.817	0.183	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.188	0.812
E10.9 Without complications	0.000	0.208	0.792
E10 Insulin-dependent diabetes mellitus	0.000	0.212	0.788
E10-E14 Diabetes mellitus	0.000	0.232	0.768
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.233	0.767
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E03.5 Myxoedema coma	0.000	0.286	0.714
E03.4 Atrophy of thyroid (acquired)	0.000	0.286	0.714
E03.3 Postinfectious hypothyroidism	0.000	0.286	0.714
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.286	0.714
E03.1 Congenital hypothyroidism without goitre	0.000	0.286	0.714
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.286	0.714
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.287	0.713
E00 Congenital iodine-deficiency syndrome	0.000	0.287	0.713
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.287	0.713
E05.8 Other thyrotoxicosis	0.000	0.288	0.711
E05.5 Thyroid crisis or storm	0.000	0.288	0.711
E05.4 Thyrotoxicosis factitia	0.000	0.288	0.711
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.288	0.711
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.288	0.711
M07.38 Other psoriatic arthropathies (Other)	0.710	0.289	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.710	0.289	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.710	0.289	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.710	0.289	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.710	0.289	0.000
E10.4 With neurological complications	0.000	0.295	0.705
E06 Thyroiditis	0.000	0.307	0.692
E10.3 With ophthalmic complications	0.000	0.350	0.650
E07.1 Dyshormogenetic goitre	0.000	0.368	0.632
E07.0 Hypersecretion of calcitonin	0.000	0.368	0.632
E03.8 Other specified hypothyroidism	0.000	0.387	0.613
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.387	0.613
E10.1 With ketoacidosis	0.000	0.397	0.603
E10.5 With peripheral circulatory complications	0.000	0.398	0.602
E07.8 Other specified disorders of thyroid	0.000	0.411	0.589
E10.7 With multiple complications	0.000	0.435	0.565
E10.6 With other specified complications	0.000	0.435	0.565
E10.2 With renal complications	0.000	0.435	0.565
E10.0 With coma	0.000	0.435	0.565
E14 Unspecified diabetes mellitus	0.000	0.439	0.560
E12 Malnutrition-related diabetes mellitus	0.000	0.449	0.550
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.459	0.541
E10.8 With unspecified complications	0.000	0.464	0.536
E50-E64 Other nutritional deficiencies	0.000	0.473	0.527
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.489	0.511
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.489	0.511
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.489	0.511
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.489	0.511
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.489	0.511
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.489	0.511
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.489	0.511
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.489	0.511
E40-E46 Malnutrition	0.000	0.499	0.500
E13 Other specified diabetes mellitus	0.000	0.501	0.499
K90 Intestinal malabsorption	0.000	0.503	0.497
E06.5 Other chronic thyroiditis	0.000	0.503	0.496
E06.4 Drug-induced thyroiditis	0.000	0.503	0.496
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.503	0.496
E06.1 Subacute thyroiditis	0.000	0.503	0.496
E06.0 Acute thyroiditis	0.000	0.503	0.496
E06.9 Thyroiditis, unspecified	0.000	0.505	0.494
E06.3 Autoimmune thyroiditis	0.000	0.521	0.478
E14.9 Without complications	0.000	0.557	0.443
M07 Psoriatic and enteropathic arthropathies	0.433	0.567	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.575	0.425
E14.3 With ophthalmic complications	0.000	0.581	0.419
E55 Vitamin D deficiency	0.000	0.594	0.405
E14.8 With unspecified complications	0.000	0.598	0.402
E14.7 With multiple complications	0.000	0.598	0.402
E14.6 With other specified complications	0.000	0.598	0.402
E14.5 With peripheral circulatory complications	0.000	0.598	0.402
E14.2 Withrenal complications	0.000	0.598	0.402
E14.1 With ketoacidosis	0.000	0.598	0.402
E14.0 With coma	0.000	0.598	0.402
E12.9 Without complications	0.000	0.605	0.395
E12.8 With unspecified complications	0.000	0.605	0.395
E12.7 With multiple complications	0.000	0.605	0.395
E12.6 With other specified complications	0.000	0.605	0.395
E12.5 With peripheral circulatory complications	0.000	0.605	0.395
E12.4 With neurological complications	0.000	0.605	0.395
E12.3 With ophthalmic complications	0.000	0.605	0.395
E12.2 With renal complications	0.000	0.605	0.395
E12.1 With ketoacidosis	0.000	0.605	0.395
E12.0 With coma	0.000	0.605	0.395
E15 Nondiabetic hypoglycaemic coma	0.000	0.612	0.388
K90.9 Intestinal malabsorption, unspecified	0.000	0.620	0.380
E16 Other disorders of pancreatic internal secretion	0.000	0.621	0.379
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.622	0.378
E63 Other nutritional deficiencies	0.000	0.622	0.378
E56 Other vitamin deficiencies	0.000	0.622	0.378
E51 Thiamine deficiency	0.000	0.622	0.378
E50 Vitamin A deficiency	0.000	0.622	0.378
E60 Dietary zinc deficiency	0.000	0.622	0.378
E59 Dietary selenium deficiency	0.000	0.622	0.378
E58 Dietary calcium deficiency	0.000	0.622	0.378
E54 Ascorbic acid deficiency	0.000	0.622	0.378
E52 Niacin deficiency [pellagra]	0.000	0.622	0.378
L40-L45 Papulosquamous disorders	0.376	0.624	0.000
E53 Deficiency of other B group vitamins	0.000	0.641	0.359
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.641	0.359
E45 Retarded development following protein-energy malnutrition	0.000	0.641	0.359
E43 Unspecified severe protein-energy malnutrition	0.000	0.641	0.359
E42 Marasmic kwashiorkor	0.000	0.641	0.359
E41 Nutritional marasmus	0.000	0.641	0.359
E40 Kwashiorkor	0.000	0.641	0.359
E13.8 With unspecified complications	0.000	0.642	0.358
E13.7 With multiple complications	0.000	0.642	0.358
E13.6 With other specified complications	0.000	0.642	0.358
E13.5 With peripheral circulatory complications	0.000	0.642	0.358
E13.4 With neurological complications	0.000	0.642	0.358
E13.3 With ophthalmic complications	0.000	0.642	0.358
E13.2 With renal complications	0.000	0.642	0.358
E13.1 With ketoacidosis	0.000	0.642	0.358
E13.0 With coma	0.000	0.642	0.358
K90.8 Other intestinal malabsorption	0.000	0.643	0.357
K90.3 Pancreatic steatorrhoea	0.000	0.643	0.357
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.643	0.357
K90.1 Tropical sprue	0.000	0.643	0.357
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.648	0.352
E04 Other non-toxic goitre	0.000	0.652	0.348
E61 Deficiency of other nutrient elements	0.000	0.661	0.339
E14.4 With neurological complications	0.000	0.663	0.337
E55.9 Vitamin D deficiency, unspecified	0.000	0.681	0.318
E65 Localised adiposity	0.000	0.688	0.312
M07.6 Other enteropathic arthropathies	0.311	0.689	0.000
M07.5 Arthropathy in ulcerative colitis	0.311	0.689	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.311	0.689	0.000
M07.2 Psoriatic spondylitis	0.311	0.689	0.000
M07.1 Arthritis mutilans	0.311	0.689	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.311	0.689	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.690	0.310
E13.9 Without complications	0.000	0.693	0.307
E67 Other hyperalimentation	0.000	0.695	0.305
E68 Sequelae of hyperalimentation	0.000	0.695	0.305
L42 Pityriasis rosea	0.292	0.708	0.000
E55.0 Rickets, active	0.000	0.709	0.291
E20-E35 Disorders of other endocrine glands	0.000	0.715	0.284
E04.9 Non-toxic goitre, unspecified	0.000	0.727	0.273
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.728	0.272
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.728	0.272
E16.4 Abnormal secretion of gastrin	0.000	0.728	0.272
E16.3 Increased secretion of glucagon	0.000	0.728	0.272
E16.1 Other hypoglycaemia	0.000	0.728	0.272
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.728	0.272
E50.9 Vitamin A deficiency, unspecified	0.000	0.729	0.271
E50.8 Other manifestations of vitamin A deficiency	0.000	0.729	0.271
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.729	0.271
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.729	0.271
E50.5 Vitamin A deficiency with night blindness	0.000	0.729	0.271
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.729	0.271
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.729	0.271
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.729	0.271
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.729	0.271
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.729	0.271
E51.9 Thiamine deficiency, unspecified	0.000	0.729	0.271
E51.8 Other manifestations of thiamine deficiency	0.000	0.729	0.271
E51.2 Wernicke's encephalopathy	0.000	0.729	0.271
E51.1 Beriberi	0.000	0.729	0.271
E56.9 Vitamin deficiency, unspecified	0.000	0.729	0.271
E56.8 Deficiency of other vitamins	0.000	0.729	0.271
E56.1 Deficiency of vitamin K	0.000	0.729	0.271
E56.0 Deficiency of vitamin E	0.000	0.729	0.271
E63.9 Nutritional deficiency, unspecified	0.000	0.729	0.271
E63.8 Other specified nutritional deficiencies	0.000	0.729	0.271
E63.1 Imbalance of constituents of food intake	0.000	0.729	0.271
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.729	0.271
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.729	0.271
E64.8 Sequelae of other nutritional deficiencies	0.000	0.729	0.271
E64.3 Sequelae of rickets	0.000	0.729	0.271
E64.2 Sequelae of vitamin C deficiency	0.000	0.729	0.271
E64.1 Sequelae of vitamin A deficiency	0.000	0.729	0.271
E64.0 Sequelae of protein-energy malnutrition	0.000	0.729	0.271
L44 Other papulosquamous disorders	0.269	0.730	0.000
L41 Parapsoriasis	0.269	0.730	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.269	0.730	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.737	0.263
E53.9 Vitamin B deficiency, unspecified	0.000	0.742	0.258
E53.1 Pyridoxine deficiency	0.000	0.742	0.258
E53.0 Riboflavin deficiency	0.000	0.742	0.258
E44.1 Mild protein-energy malnutrition	0.000	0.742	0.257
E44.0 Moderate protein-energy malnutrition	0.000	0.742	0.257
E04.8 Other specified non-toxic goitre	0.000	0.750	0.249
E61.9 Deficiency of nutrient element, unspecified	0.000	0.757	0.243
E61.8 Deficiency of other specified nutrient elements	0.000	0.757	0.243
E61.7 Deficiency of multiple nutrient elements	0.000	0.757	0.243
E61.6 Vanadium deficiency	0.000	0.757	0.243
E61.5 Molybdenum deficiency	0.000	0.757	0.243
E61.4 Chromium deficiency	0.000	0.757	0.243
E61.3 Manganese deficiency	0.000	0.757	0.243
E61.2 Magnesium deficiency	0.000	0.757	0.243
E61.0 Copper deficiency	0.000	0.757	0.243
E53.8 Deficiency of other specified B group vitamins	0.000	0.761	0.239
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.223	0.777	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.223	0.777	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.223	0.777	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.223	0.777	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.223	0.777	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.223	0.777	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.223	0.777	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.223	0.777	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.223	0.777	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.223	0.777	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.223	0.777	0.000
M07.18 Arthritis mutilans (Other)	0.223	0.777	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.223	0.777	0.000
M07.16 Arthritis mutilans (Lower leg)	0.223	0.777	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.223	0.777	0.000
M07.14 Arthritis mutilans (Hand)	0.223	0.777	0.000
M07.13 Arthritis mutilans (Forearm)	0.223	0.777	0.000
M07.12 Arthritis mutilans (Upper arm)	0.223	0.777	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.223	0.777	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.223	0.777	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.223	0.777	0.000
M07.28 Psoriatic spondylitis (Other)	0.223	0.777	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.223	0.777	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.223	0.777	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.223	0.777	0.000
M07.24 Psoriatic spondylitis (Hand)	0.223	0.777	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.223	0.777	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.223	0.777	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.223	0.777	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.223	0.777	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.223	0.777	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.223	0.777	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.223	0.777	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.223	0.777	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.223	0.777	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.223	0.777	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.223	0.777	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.223	0.777	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.223	0.777	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.223	0.777	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.223	0.777	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.223	0.777	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.223	0.777	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.223	0.777	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.223	0.777	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.223	0.777	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.223	0.777	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.223	0.777	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.223	0.777	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.223	0.777	0.000
M07.69 Other enteropathic arthropathies (Site unspecified)	0.223	0.777	0.000
M07.68 Other enteropathic arthropathies (Other)	0.223	0.777	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.223	0.777	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.223	0.777	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.223	0.777	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.223	0.777	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.223	0.777	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.223	0.777	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.223	0.777	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.223	0.777	0.000
E27 Other disorders of adrenal gland	0.000	0.780	0.220
E29 Testicular dysfunction	0.000	0.781	0.219
E67.8 Other specified hyperalimentation	0.000	0.781	0.219
E67.3 Hypervitaminosis D	0.000	0.781	0.219
E67.2 Megavitamin-B6 syndrome	0.000	0.781	0.219
E67.1 Hypercarotenaemia	0.000	0.781	0.219
E67.0 Hypervitaminosis A	0.000	0.781	0.219
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.796	0.204
E32 Diseases of thymus	0.000	0.796	0.204
E31 Polyglandular dysfunction	0.000	0.796	0.204
E30 Disorders of puberty, not elsewhere classified	0.000	0.796	0.204
E25 Adrenogenital disorders	0.000	0.796	0.204
E20 Hypoparathyroidism	0.000	0.796	0.204
E61.1 Iron deficiency	0.000	0.796	0.204
E22 Hyperfunction of pituitary gland	0.000	0.800	0.200
E34 Other endocrine disorders	0.000	0.801	0.198
E26 Hyperaldosteronism	0.000	0.803	0.197
E04.0 Non-toxic diffuse goitre	0.000	0.805	0.195
L41.9 Parapsoriasis, unspecified	0.193	0.807	0.000
L41.8 Other parapsoriasis	0.193	0.807	0.000
L41.5 Retiform parapsoriasis	0.193	0.807	0.000
L41.4 Large plaque parapsoriasis	0.193	0.807	0.000
L41.3 Small plaque parapsoriasis	0.193	0.807	0.000
L41.2 Lymphomatoid papulosis	0.193	0.807	0.000
L41.1 Pityriasis lichenoides chronica	0.193	0.807	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.193	0.807	0.000
L44.9 Papulosquamous disorder, unspecified	0.193	0.807	0.000
L44.8 Other specified papulosquamous disorders	0.193	0.807	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.193	0.807	0.000
L44.3 Lichen ruber moniliformis	0.193	0.807	0.000
L44.2 Lichen striatus	0.193	0.807	0.000
L44.1 Lichen nitidus	0.193	0.807	0.000
L44.0 Pityriasis rubra pilaris	0.193	0.807	0.000
L43 Lichen planus	0.193	0.807	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.815	0.185
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.817	0.182
E28 Ovarian dysfunction	0.000	0.827	0.172
E29.1 Testicular hypofunction	0.000	0.828	0.171
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.831	0.169
E66 Obesity	0.000	0.836	0.164
E04.1 Non-toxic single thyroid nodule	0.000	0.836	0.164
J33 Nasal polyp	0.000	0.838	0.162
E27.5 Adrenomedullary hyperfunction	0.000	0.842	0.158
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.842	0.158
E27.0 Other adrenocortical overactivity	0.000	0.842	0.158
E27.8 Other specified disorders of adrenal gland	0.000	0.842	0.158
J33.9 Nasal polyp, unspecified	0.000	0.842	0.158
E29.9 Testicular dysfunction, unspecified	0.000	0.843	0.157
E29.8 Other testicular dysfunction	0.000	0.843	0.157
E29.0 Testicular hyperfunction	0.000	0.843	0.157
J33.8 Other polyp of sinus	0.000	0.844	0.156
J33.0 Polyp of nasal cavity	0.000	0.848	0.152
J47 Bronchiectasis	0.000	0.851	0.149
E27.2 Addisonian crisis	0.000	0.852	0.148
E23 Hypofunction and other disorders of pituitary gland	0.000	0.852	0.147
E20.9 Hypoparathyroidism, unspecified	0.000	0.853	0.146
E20.8 Other hypoparathyroidism	0.000	0.853	0.146
E20.1 Pseudohypoparathyroidism	0.000	0.853	0.146
E20.0 Idiopathic hypoparathyroidism	0.000	0.853	0.146
E25.9 Adrenogenital disorder, unspecified	0.000	0.853	0.146
E25.8 Other adrenogenital disorders	0.000	0.853	0.146
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.853	0.146
E30.9 Disorder of puberty, unspecified	0.000	0.853	0.146
E30.8 Other disorders of puberty	0.000	0.853	0.146
E30.1 Precocious puberty	0.000	0.853	0.146
E30.0 Delayed puberty	0.000	0.853	0.146
E31.9 Polyglandular dysfunction, unspecified	0.000	0.853	0.146
E31.8 Other polyglandular dysfunction	0.000	0.853	0.146
E31.1 Polyglandular hyperfunction	0.000	0.853	0.146
E31.0 Autoimmune polyglandular failure	0.000	0.853	0.146
E32.9 Disease of thymus, unspecified	0.000	0.853	0.146
E32.8 Other diseases of thymus	0.000	0.853	0.146
E32.1 Abscess of thymus	0.000	0.853	0.146
E32.0 Persistent hyperplasia of thymus	0.000	0.853	0.146
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.853	0.146
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.853	0.146
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.853	0.146
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.857	0.143
E22.8 Other hyperfunction of pituitary gland	0.000	0.857	0.143
E22.1 Hyperprolactinaemia	0.000	0.857	0.143
E34.8 Other specified endocrine disorders	0.000	0.857	0.142
E34.5 Androgen resistance syndrome	0.000	0.857	0.142
E34.4 Constitutional tall stature	0.000	0.857	0.142
E34.3 Short stature, not elsewhere classified	0.000	0.857	0.142
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.857	0.142
E34.1 Other hypersecretion of intestinal hormones	0.000	0.857	0.142
E34.0 Carcinoid syndrome	0.000	0.857	0.142
E24 Cushing's syndrome	0.001	0.858	0.142
E22.0 Acromegaly and pituitary gigantism	0.000	0.858	0.142
E26.9 Hyperaldosteronism, unspecified	0.000	0.859	0.141
E26.8 Other hyperaldosteronism	0.000	0.859	0.141
E26.1 Secondary hyperaldosteronism	0.000	0.859	0.141
E21.0 Primary hyperparathyroidism	0.000	0.859	0.141
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.860	0.140
L43.8 Other lichen planus	0.138	0.861	0.000
L43.3 Subacute (active) lichen planus	0.138	0.861	0.000
L43.2 Lichenoid drug reaction	0.138	0.861	0.000
L43.1 Bullous lichen planus	0.138	0.861	0.000
L43.0 Hypertrophic lichen planus	0.138	0.861	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.861	0.138
E34.9 Endocrine disorder, unspecified	0.000	0.863	0.137
E27.9 Disorder of adrenal gland, unspecified	0.000	0.863	0.136
E26.0 Primary hyperaldosteronism	0.000	0.866	0.134
J30-J39 Other diseases of upper respiratory tract	0.000	0.866	0.134
J45.9 Asthma, unspecified	0.000	0.867	0.133
J45 Asthma	0.000	0.867	0.133
J40-J47 Chronic lower respiratory diseases	0.000	0.867	0.133
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.869	0.131
E21.4 Other specified disorders of parathyroid gland	0.000	0.869	0.131
E21.2 Other hyperparathyroidism	0.000	0.869	0.131
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.872	0.128
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.000	0.875	0.125
E28.9 Ovarian dysfunction, unspecified	0.000	0.876	0.124
E28.8 Other ovarian dysfunction	0.000	0.876	0.124
E28.3 Primary ovarian failure	0.000	0.876	0.124
E28.1 Androgen excess	0.000	0.876	0.124
E28.0 Oestrogen excess	0.000	0.876	0.124
E23.2 Diabetes insipidus	0.000	0.880	0.119
J31.0 Chronic rhinitis	0.000	0.881	0.119
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.882	0.118
E66.1 Drug-induced obesity	0.000	0.882	0.118
J33.1 Polypoid sinus degeneration	0.000	0.884	0.116
Chapter X Diseases of the respiratory system	0.000	0.887	0.113
E66.0 Obesity due to excess calories	0.000	0.889	0.111
J36 Peritonsillar abscess	0.000	0.889	0.111
J30 Vasomotor and allergic rhinitis	0.000	0.892	0.108
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.894	0.106
E23.1 Drug-induced hypopituitarism	0.000	0.894	0.106
J45.0 Predominantly allergic asthma	0.000	0.897	0.103
E24.8 Other Cushing's syndrome	0.001	0.898	0.102
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.001	0.898	0.102
E24.3 Ectopic ACTH syndrome	0.001	0.898	0.102
E24.2 Drug-induced Cushing's syndrome	0.001	0.898	0.102
E24.1 Nelson's syndrome	0.001	0.898	0.102
J42 Unspecified chronic bronchitis	0.000	0.900	0.100
E66.8 Other obesity	0.000	0.901	0.099
J32 Chronic sinusitis	0.000	0.904	0.096
E21.3 Hyperparathyroidism, unspecified	0.000	0.904	0.095
J45.8 Mixed asthma	0.000	0.905	0.095
J45.1 Nonallergic asthma	0.000	0.905	0.095
J41 Simple and mucopurulent chronic bronchitis	0.000	0.905	0.095
J37 Chronic laryngitis and laryngotracheitis	0.000	0.905	0.095
E28.2 Polycystic ovarian syndrome	0.000	0.907	0.092
E23.6 Other disorders of pituitary gland	0.001	0.908	0.091
E23.7 Disorder of pituitary gland, unspecified	0.001	0.909	0.091
J31.2 Chronic pharyngitis	0.000	0.910	0.090
J31.1 Chronic nasopharyngitis	0.000	0.910	0.090
J30.3 Other allergic rhinitis	0.000	0.910	0.089
J34 Other disorders of nose and nasal sinuses	0.000	0.914	0.086
J00-J06 Acute upper respiratory infections	0.000	0.916	0.084
E24.0 Pituitary-dependent Cushing's disease	0.001	0.917	0.082
J34.2 Deviated nasal septum	0.000	0.918	0.082
J30.1 Allergic rhinitis due to pollen	0.000	0.918	0.082
K90-K93 Other diseases of the digestive system	0.000	0.920	0.080
J46 Status asthmaticus	0.000	0.922	0.078
J32.0 Chronic maxillary sinusitis	0.000	0.922	0.078
J30.2 Other seasonal allergic rhinitis	0.000	0.922	0.078
J30.0 Vasomotor rhinitis	0.000	0.922	0.078
J60-J70 Lung diseases due to external agents	0.000	0.924	0.076
J95-J99 Other diseases of the respiratory system	0.000	0.926	0.074
E24.9 Cushing's syndrome, unspecified	0.001	0.926	0.073
J32.2 Chronic ethmoidal sinusitis	0.000	0.926	0.074
J30.4 Allergic rhinitis, unspecified	0.000	0.926	0.073
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.000	0.927	0.073
J43 Emphysema	0.000	0.927	0.073
J03 Acute tonsillitis	0.000	0.929	0.071
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.929	0.071
E23.0 Hypopituitarism	0.001	0.930	0.069
J32.3 Chronic sphenoidal sinusitis	0.000	0.931	0.069
J32.1 Chronic frontal sinusitis	0.000	0.931	0.069
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.931	0.068
J41.1 Mucopurulent chronic bronchitis	0.000	0.931	0.068
J41.0 Simple chronic bronchitis	0.000	0.931	0.068
J37.1 Chronic laryngotracheitis	0.000	0.932	0.068
J37.0 Chronic laryngitis	0.000	0.933	0.067
J39 Other diseases of upper respiratory tract	0.000	0.933	0.066
J32.8 Other chronic sinusitis	0.000	0.934	0.066
J32.4 Chronic pansinusitis	0.000	0.934	0.066
J40 Bronchitis, not specified as acute or chronic	0.000	0.934	0.065
J34.0 Abscess, furuncle and carbuncle of nose	0.000	0.935	0.065
J00 Acute nasopharyngitis [common cold]	0.000	0.935	0.065
J01 Acute sinusitis	0.000	0.937	0.063
J99 Respiratory disorders in diseases classified elsewhere	0.000	0.938	0.062
L43.9 Lichen planus, unspecified	0.062	0.938	0.001
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.000	0.938	0.062
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.938	0.062
J03.9 Acute tonsillitis, unspecified	0.000	0.938	0.062
J04 Acute laryngitis and tracheitis	0.000	0.940	0.060
J34.1 Cyst and mucocele of nose and nasal sinus	0.000	0.941	0.059
J32.9 Chronic sinusitis, unspecified	0.000	0.942	0.058
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.943	0.057
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.943	0.057
J69 Pneumonitis due to solids and liquids	0.000	0.944	0.056
J70 Respiratory conditions due to other external agents	0.000	0.945	0.055
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.000	0.945	0.055
J67 Hypersensitivity pneumonitis due to organic dust	0.000	0.945	0.055
J66 Airway disease due to specific organic dust	0.000	0.945	0.055
J63 Pneumoconiosis due to other inorganic dusts	0.000	0.945	0.055
J62 Pneumoconiosis due to dust containing silica	0.000	0.945	0.055
J65 Pneumoconiosis associated with tuberculosis	0.000	0.945	0.055
J64 Unspecified pneumoconiosis	0.000	0.945	0.055
J60 Coalworker's pneumoconiosis	0.000	0.945	0.055
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.945	0.055
J38.2 Nodules of vocal cords	0.000	0.947	0.053
J96 Respiratory failure, not elsewhere classified	0.000	0.947	0.053
J02 Acute pharyngitis	0.000	0.947	0.053
J90-J94 Other diseases of pleura	0.000	0.947	0.053
J20-J22 Other acute lower respiratory infections	0.000	0.947	0.052
J43.2 Centrilobular emphysema	0.000	0.948	0.052
J85 Abscess of lung and mediastinum	0.000	0.948	0.052
J43.8 Other emphysema	0.000	0.948	0.052
J43.1 Panlobular emphysema	0.000	0.948	0.052
J43.0 MacLeod's syndrome	0.000	0.948	0.052
J03.8 Acute tonsillitis due to other specified organisms	0.000	0.949	0.051
J03.0 Streptococcal tonsillitis	0.000	0.949	0.051
J80 Adult respiratory distress syndrome	0.000	0.949	0.051
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.949	0.051
J35 Chronic diseases of tonsils and adenoids	0.000	0.949	0.050
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.000	0.950	0.050
E66.9 Obesity, unspecified	0.000	0.951	0.049
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.951	0.048
J39.9 Disease of upper respiratory tract, unspecified	0.000	0.952	0.048
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.000	0.952	0.048
J39.1 Other abscess of pharynx	0.000	0.952	0.048
J39.0 Retropharyngeal and parapharyngeal abscess	0.000	0.952	0.048
J95.8 Other postprocedural respiratory disorders	0.000	0.953	0.047

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations