TreeWAS – Variant ID: rs28732175

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
J40-J47 Chronic lower respiratory diseases	0.000	0.000	1.000
T36-T50 Poisoning by drugs, medicaments and biological substances	1.000	0.000	0.000
Chapter V Mental and behavioural disorders	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
J30-J39 Other diseases of upper respiratory tract	0.000	0.000	1.000
J33 Nasal polyp	0.000	0.000	1.000
J45.9 Asthma, unspecified	0.000	0.000	1.000
J45 Asthma	0.000	0.000	1.000
J47 Bronchiectasis	0.000	0.000	1.000
Chapter X Diseases of the respiratory system	0.000	0.000	1.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
F30-F39 Mood [affective] disorders	0.999	0.001	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.999	0.001	0.000
E03 Other hypothyroidism	0.000	0.002	0.998
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.997	0.003	0.000
J33.9 Nasal polyp, unspecified	0.000	0.003	0.997
L40-L45 Papulosquamous disorders	0.997	0.003	0.000
E00-E07 Disorders of thyroid gland	0.000	0.003	0.997
Chapter VI Diseases of the nervous system	0.996	0.004	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.995	0.005	0.000
F41 Other anxiety disorders	0.994	0.006	0.000
T39.1 4-Aminophenol derivatives	0.993	0.007	0.000
J33.0 Polyp of nasal cavity	0.000	0.008	0.992
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.008	0.991
M07.3 Other psoriatic arthropathies	0.991	0.009	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.988	0.012	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.983	0.017	0.000
F32 Depressive episode	0.982	0.018	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.982	0.018	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.982	0.018	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.982	0.018	0.000
F60-F69 Disorders of adult personality and behaviour	0.977	0.023	0.000
M07 Psoriatic and enteropathic arthropathies	0.974	0.025	0.002
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.975	0.025	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.026	0.974
G40-G47 Episodic and paroxysmal disorders	0.970	0.030	0.000
L40.0 Psoriasis vulgaris	0.968	0.032	0.000
M05-M14 Inflammatory polyarthropathies	0.962	0.034	0.004
F17 Mental and behavioural disorders due to use of tobacco	0.963	0.037	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.961	0.038	0.001
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.039	0.961
G40 Epilepsy	0.959	0.041	0.000
F32.9 Depressive episode, unspecified	0.959	0.041	0.000
F31 Bipolar affective disorder	0.957	0.043	0.000
T43.2 Other and unspecified antidepressants	0.954	0.046	0.000
F60 Specific personality disorders	0.952	0.048	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.934	0.066	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.930	0.070	0.000
E07 Other disorders of thyroid	0.000	0.075	0.925
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.923	0.077	0.000
F17.1 Harmful use	0.922	0.078	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.918	0.082	0.000
F41.2 Mixed anxiety and depressive disorder	0.917	0.083	0.000
F33 Recurrent depressive disorder	0.915	0.085	0.000
J44 Other chronic obstructive pulmonary disease	0.000	0.090	0.910
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.908	0.092	0.000
F17.2 Dependence syndrome	0.906	0.094	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.906	0.094	0.000
G20-G26 Extrapyramidal and movement disorders	0.905	0.095	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.000	0.097	0.903
F45 Somatoform disorders	0.899	0.101	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.898	0.102	0.000
G70-G73 Diseases of myoneural junction and muscle	0.897	0.103	0.000
F60.9 Personality disorder, unspecified	0.896	0.104	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.895	0.105	0.000
J33.8 Other polyp of sinus	0.000	0.106	0.894
E07.9 Disorder of thyroid, unspecified	0.000	0.114	0.886
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.121	0.879
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.877	0.123	0.000
F41.9 Anxiety disorder, unspecified	0.876	0.124	0.000
F41.1 Generalised anxiety disorder	0.869	0.131	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.868	0.132	0.000
F60.3 Emotionally unstable personality disorder	0.868	0.132	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.866	0.133	0.000
F30 Manic episode	0.864	0.136	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.864	0.136	0.000
T42.4 Benzodiazepines	0.862	0.138	0.000
Chapter XXII Codes for special purposes	0.861	0.139	0.000
Chapter XX External causes of morbidity and mortality	0.860	0.140	0.000
J60-J70 Lung diseases due to external agents	0.000	0.148	0.852
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.153	0.847
G50-G59 Nerve, nerve root and plexus disorders	0.846	0.154	0.000
T51 Toxic effect of alcohol	0.842	0.158	0.000
J34 Other disorders of nose and nasal sinuses	0.000	0.159	0.841
J30 Vasomotor and allergic rhinitis	0.000	0.159	0.841
Q50-Q56 Congenital malformations of genital organs	0.839	0.160	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.095	0.161	0.743
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.838	0.162	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.838	0.162	0.000
F32.1 Moderate depressive episode	0.838	0.162	0.000
J31.0 Chronic rhinitis	0.000	0.167	0.833
S32 Fracture of lumbar spine and pelvis	0.832	0.168	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.832	0.168	0.000
F45.8 Other somatoform disorders	0.828	0.172	0.000
G70 Myasthenia gravis and other myoneural disorders	0.825	0.174	0.000
F31.9 Bipolar affective disorder, unspecified	0.823	0.177	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.822	0.178	0.000
Q80-Q89 Other congenital malformations	0.822	0.178	0.000
F31.8 Other bipolar affective disorders	0.820	0.180	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.819	0.181	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.817	0.183	0.000
G90-G99 Other disorders of the nervous system	0.814	0.186	0.000
G56 Mononeuropathies of upper limb	0.812	0.188	0.000
G45.3 Amaurosis fugax	0.812	0.188	0.000
F40 Phobic anxiety disorders	0.812	0.188	0.000
Q21 Congenital malformations of cardiac septa	0.811	0.189	0.000
J36 Peritonsillar abscess	0.000	0.189	0.811
Chapter II Neoplasms	0.808	0.192	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.194	0.806
W20-W49 Exposure to inanimate mechanical forces	0.804	0.196	0.000
Q60-Q64 Congenital malformations of the urinary system	0.801	0.199	0.000
G20 Parkinson's disease	0.800	0.200	0.000
G40.5 Special epileptic syndromes	0.797	0.203	0.000
E10-E14 Diabetes mellitus	0.056	0.203	0.741
J42 Unspecified chronic bronchitis	0.000	0.205	0.795
J00-J06 Acute upper respiratory infections	0.000	0.207	0.793
M60-M63 Disorders of muscles	0.792	0.208	0.001
F44 Dissociative [conversion] disorders	0.791	0.209	0.000
F69 Unspecified disorder of adult personality and behaviour	0.791	0.209	0.000
E06 Thyroiditis	0.000	0.210	0.790
S10-S19 Injuries to the neck	0.789	0.211	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.787	0.213	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.787	0.213	0.000
J34.2 Deviated nasal septum	0.000	0.214	0.786
G24 Dystonia	0.786	0.214	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.786	0.214	0.000
Chapter VIII Diseases of the ear and mastoid process	0.785	0.215	0.000
Chapter I Certain infectious and parasitic diseases	0.783	0.217	0.000
M91-M94 Chondropathies	0.782	0.217	0.001
G56.0 Carpal tunnel syndrome	0.783	0.217	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.782	0.218	0.000
F42 Obsessive-compulsive disorder	0.781	0.219	0.000
J32 Chronic sinusitis	0.000	0.222	0.778
G40.7 Petit mal, unspecified, without grand mal seizures	0.778	0.222	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.777	0.223	0.000
T51.0 Ethanol	0.775	0.225	0.000
G70.0 Myasthenia gravis	0.774	0.226	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.771	0.229	0.000
E10 Insulin-dependent diabetes mellitus	0.007	0.230	0.763
T46 Poisoning by agents primarily affecting the cardiovascular system	0.770	0.230	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.767	0.233	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.766	0.234	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.765	0.235	0.000
E10.9 Without complications	0.000	0.236	0.764
F31.0 Bipolar affective disorder, current episode hypomanic	0.763	0.236	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.762	0.238	0.000
S90-S99 Injuries to the ankle and foot	0.762	0.238	0.000
M45-M49 Spondylopathies	0.761	0.238	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.761	0.239	0.000
T42.1 Iminostilbenes	0.758	0.242	0.000
J45.0 Predominantly allergic asthma	0.000	0.244	0.756
T15-T19 Effects of foreign body entering through natural orifice	0.755	0.245	0.000
G51 Facial nerve disorders	0.750	0.250	0.000
J03 Acute tonsillitis	0.000	0.250	0.749
K90 Intestinal malabsorption	0.072	0.252	0.676
J81 Pulmonary oedema	0.000	0.252	0.748
Q21.1 Atrial septal defect	0.748	0.252	0.000
T79-T79 Certain early complications of trauma	0.748	0.252	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.747	0.253	0.000
T39.0 Salicylates	0.745	0.255	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.743	0.257	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.743	0.257	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.742	0.258	0.000
C15-C26 Malignant neoplasms of digestive organs	0.740	0.260	0.000
X60-X84 Intentional self-harm	0.735	0.265	0.000
J84 Other interstitial pulmonary diseases	0.000	0.265	0.735
S31 Open wound of abdomen, lower back and pelvis	0.733	0.267	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.732	0.268	0.000
M40-M43 Deforming dorsopathies	0.731	0.268	0.001
J30.1 Allergic rhinitis due to pollen	0.000	0.270	0.730
W22 Striking against or struck by other objects	0.728	0.272	0.000
L50-L54 Urticaria and erythema	0.726	0.274	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.724	0.276	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.723	0.277	0.000
G96 Other disorders of central nervous system	0.720	0.280	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.281	0.719
G80-G83 Cerebral palsy and other paralytic syndromes	0.717	0.283	0.000
L40.8 Other psoriasis	0.717	0.283	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
L40.1 Generalised pustular psoriasis	0.717	0.283	0.000
J41 Simple and mucopurulent chronic bronchitis	0.000	0.283	0.717
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.717	0.283	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.717	0.283	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.717	0.283	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.717	0.283	0.000
T36 Poisoning by systemic antibiotics	0.717	0.283	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.717	0.283	0.000
F70-F79 Mental retardation	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
J33.1 Polypoid sinus degeneration	0.000	0.283	0.717
J37 Chronic laryngitis and laryngotracheitis	0.000	0.283	0.717
J45.8 Mixed asthma	0.000	0.283	0.717
J45.1 Nonallergic asthma	0.000	0.283	0.717
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
F38 Other mood [affective] disorders	0.717	0.283	0.000
F34 Persistent mood [affective] disorders	0.717	0.283	0.000
F39 Unspecified mood [affective] disorder	0.717	0.283	0.000
F48 Other neurotic disorders	0.716	0.284	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.716	0.284	0.000
F32.0 Mild depressive episode	0.716	0.284	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.716	0.284	0.000
E03.8 Other specified hypothyroidism	0.000	0.284	0.715
E03.5 Myxoedema coma	0.000	0.284	0.715
E03.4 Atrophy of thyroid (acquired)	0.000	0.284	0.715
E03.3 Postinfectious hypothyroidism	0.000	0.284	0.715
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.284	0.715
E03.1 Congenital hypothyroidism without goitre	0.000	0.284	0.715
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.284	0.715
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.715	0.285	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.715	0.285	0.000
T39.4 Antirheumatics, not elsewhere classified	0.715	0.285	0.000
T39.2 Pyrazolone derivatives	0.715	0.285	0.000
L44 Other papulosquamous disorders	0.715	0.285	0.000
L41 Parapsoriasis	0.715	0.285	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.715	0.285	0.000
L42 Pityriasis rosea	0.715	0.285	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.285	0.714
E00 Congenital iodine-deficiency syndrome	0.000	0.285	0.714
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.285	0.714
F80-F89 Disorders of psychological development	0.714	0.285	0.000
S32.4 Fracture of acetabulum	0.714	0.286	0.000
L10-L14 Bullous disorders	0.714	0.286	0.000
E10.3 With ophthalmic complications	0.002	0.287	0.712
F41.8 Other specified anxiety disorders	0.713	0.287	0.000
F41.3 Other mixed anxiety disorders	0.713	0.287	0.000
Q00-Q07 Congenital malformations of the nervous system	0.713	0.287	0.000
F30.0 Hypomania	0.711	0.289	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.000	0.289	0.711
E05.8 Other thyrotoxicosis	0.000	0.289	0.711
E05.5 Thyroid crisis or storm	0.000	0.289	0.711
E05.4 Thyrotoxicosis factitia	0.000	0.289	0.711
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.289	0.711
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.289	0.711
M07.38 Other psoriatic arthropathies (Other)	0.710	0.290	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.710	0.290	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.710	0.290	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.710	0.290	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.710	0.290	0.000
F30.9 Manic episode, unspecified	0.708	0.292	0.000
F99-F99 Unspecified mental disorder	0.707	0.292	0.000
B35-B49 Mycoses	0.707	0.293	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.705	0.295	0.000
J32.0 Chronic maxillary sinusitis	0.000	0.295	0.705
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.705	0.295	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.705	0.295	0.000
T42.3 Barbiturates	0.705	0.295	0.000
T42.2 Succinimides and oxazolidinediones	0.705	0.295	0.000
T42.0 Hydantoin derivatives	0.705	0.295	0.000
F32.8 Other depressive episodes	0.704	0.296	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.704	0.296	0.000
Q35-Q37 Cleft lip and cleft palate	0.704	0.296	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.704	0.296	0.000
T43.9 Psychotropic drug, unspecified	0.704	0.296	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.704	0.296	0.000
T43.6 Psychostimulants with abuse potential	0.704	0.296	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.704	0.296	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.704	0.296	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.702	0.298	0.000
S40-S49 Injuries to the shoulder and upper arm	0.701	0.299	0.000
G24.9 Dystonia, unspecified	0.701	0.299	0.000
F68 Other disorders of adult personality and behaviour	0.700	0.300	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.700	0.300	0.000
F65 Disorders of sexual preference	0.700	0.300	0.000
F64 Gender identity disorders	0.700	0.300	0.000
F63 Habit and impulse disorders	0.700	0.300	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.700	0.300	0.000
F61 Mixed and other personality disorders	0.700	0.300	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.300	0.700
M07.6 Other enteropathic arthropathies	0.698	0.301	0.001
M07.5 Arthropathy in ulcerative colitis	0.698	0.301	0.001
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.698	0.301	0.001
M07.2 Psoriatic spondylitis	0.698	0.301	0.001
M07.1 Arthritis mutilans	0.698	0.301	0.001
M07.0 Distal interphalangeal psoriatic arthropathy	0.698	0.301	0.001
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.699	0.301	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.699	0.301	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.699	0.301	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.699	0.301	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.699	0.301	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.699	0.301	0.000
F11 Mental and behavioural disorders due to use of opioids	0.699	0.301	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.000	0.302	0.698
Q38-Q45 Other congenital malformations of the digestive system	0.698	0.302	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.697	0.303	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.696	0.304	0.000
M14 Arthropathies in other diseases classified elsewhere	0.690	0.307	0.003
M12 Other specific arthropathies	0.689	0.307	0.003
M09 Juvenile arthritis in diseases classified elsewhere	0.689	0.307	0.003
M08 Juvenile arthritis	0.689	0.307	0.003
M46 Other inflammatory spondylopathies	0.692	0.308	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.692	0.308	0.000
J46 Status asthmaticus	0.000	0.308	0.692
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.692	0.308	0.000
F17.9 Unspecified mental and behavioural disorder	0.690	0.310	0.000
F17.8 Other mental and behavioural disorders	0.690	0.310	0.000
F17.7 Residual and late-onset psychotic disorder	0.690	0.310	0.000
F17.6 Amnesic syndrome	0.690	0.310	0.000
F17.5 Psychotic disorder	0.690	0.310	0.000
F17.4 Withdrawal state with delirium	0.690	0.310	0.000
F17.3 Withdrawal state	0.690	0.310	0.000
F17.0 Acute intoxication	0.690	0.310	0.000
Chapter XI Diseases of the digestive system	0.689	0.311	0.000
G40.8 Other epilepsy	0.688	0.312	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.688	0.312	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.688	0.312	0.000
M11 Other crystal arthropathies	0.685	0.313	0.003
Q51 Congenital malformations of uterus and cervix	0.687	0.313	0.000
G45.4 Transient global amnesia	0.687	0.313	0.000
J69 Pneumonitis due to solids and liquids	0.000	0.313	0.687
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.686	0.314	0.000
F33.9 Recurrent depressive disorder, unspecified	0.686	0.314	0.000
F31.7 Bipolar affective disorder, currently in remission	0.686	0.314	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.686	0.314	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.686	0.314	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.686	0.314	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.685	0.315	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.685	0.315	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.684	0.316	0.000
K80 Cholelithiasis	0.683	0.317	0.000
F60.8 Other specific personality disorders	0.683	0.317	0.000
F60.7 Dependent personality disorder	0.683	0.317	0.000
F60.6 Anxious [avoidant] personality disorder	0.683	0.317	0.000
F60.5 Anankastic personality disorder	0.683	0.317	0.000
F60.4 Histrionic personality disorder	0.683	0.317	0.000
F60.2 Dissocial personality disorder	0.683	0.317	0.000
F60.1 Schizoid personality disorder	0.683	0.317	0.000
F60.0 Paranoid personality disorder	0.683	0.317	0.000
U80 Agent resistant to penicillin and related antibiotics	0.681	0.319	0.000
W44 Foreign body entering into or through eye or natural orifice	0.679	0.321	0.000
M00-M03 Infectious arthropathies	0.677	0.322	0.001
V80-V89 Other land transport accidents	0.677	0.323	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.677	0.323	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.323	0.677
T51.9 Alcohol, unspecified	0.676	0.324	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.676	0.324	0.000
S32.0 Fracture of lumbar vertebra	0.676	0.324	0.000
C18 Malignant neoplasm of colon	0.675	0.325	0.000
S70-S79 Injuries to the hip and thigh	0.674	0.326	0.001
W22.9 Unspecified place	0.674	0.326	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.673	0.326	0.001
C18.7 Sigmoid colon	0.674	0.326	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.673	0.327	0.000
D00-D09 In situ neoplasms	0.672	0.328	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.671	0.329	0.000
M62 Other disorders of muscle	0.670	0.330	0.000
H65-H75 Diseases of middle ear and mastoid	0.670	0.330	0.000
Q54 Hypospadias	0.670	0.330	0.000
M13 Other arthritis	0.667	0.331	0.002
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.669	0.331	0.000
G44 Other headache syndromes	0.668	0.332	0.000
S32.1 Fracture of sacrum	0.668	0.332	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.665	0.334	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.665	0.335	0.000
Q21.0 Ventricular septal defect	0.665	0.335	0.000
E07.1 Dyshormogenetic goitre	0.000	0.336	0.663
E07.0 Hypersecretion of calcitonin	0.000	0.336	0.663
K80.4 Calculus of bile duct with cholecystitis	0.661	0.339	0.000
G41 Status epilepticus	0.660	0.340	0.000
G61 Inflammatory polyneuropathy	0.659	0.340	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.658	0.341	0.000
S37 Injury of urinary and pelvic organs	0.658	0.341	0.000
S36 Injury of intra-abdominal organs	0.658	0.341	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.658	0.341	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.658	0.341	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.658	0.341	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.658	0.342	0.000
V40-V49 Car occupant injured in transport accident	0.657	0.343	0.000
B37 Candidiasis	0.657	0.343	0.000
C21 Malignant neoplasm of anus and anal canal	0.657	0.343	0.000
F33.8 Other recurrent depressive disorders	0.656	0.344	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.656	0.344	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.656	0.344	0.000
G71 Primary disorders of muscles	0.654	0.346	0.000
Q82 Other congenital malformations of skin	0.653	0.347	0.000
Q83 Congenital malformations of breast	0.653	0.347	0.000
T65 Toxic effect of other and unspecified substances	0.651	0.349	0.000
T63 Toxic effect of contact with venomous animals	0.651	0.349	0.000
T62 Toxic effect of other noxious substances eaten as food	0.651	0.349	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.651	0.349	0.000
T60 Toxic effect of pesticides	0.651	0.349	0.000
T59 Toxic effect of other gases, fumes and vapours	0.651	0.349	0.000
T57 Toxic effect of other inorganic substances	0.651	0.349	0.000
T56 Toxic effect of metals	0.651	0.349	0.000
T54 Toxic effect of corrosive substances	0.651	0.349	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.651	0.349	0.000
T52 Toxic effect of organic solvents	0.651	0.349	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.651	0.349	0.000
T58 Toxic effect of carbon monoxide	0.651	0.349	0.000
T55 Toxic effect of soaps and detergents	0.651	0.349	0.000
F40.0 Agoraphobia	0.651	0.349	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.650	0.350	0.000
T38.9 Other and unspecified hormone antagonists	0.649	0.350	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.649	0.350	0.000
T38.7 Androgens and anabolic congeners	0.649	0.350	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.649	0.350	0.000
T38.5 Other oestrogens and progestogens	0.649	0.350	0.000
T38.4 Oral contraceptives	0.649	0.350	0.000
T38.2 Antithyroid drugs	0.649	0.350	0.000
T38.1 Thyroid hormones and substitutes	0.649	0.350	0.000
T38.0 Glucocorticoids and synthetic analogues	0.649	0.350	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.649	0.351	0.000
J34.0 Abscess, furuncle and carbuncle of nose	0.000	0.351	0.649
G23 Other degenerative diseases of basal ganglia	0.649	0.351	0.000
G21 Secondary Parkinsonism	0.649	0.351	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.649	0.351	0.000
G22 Parkinsonism in diseases classified elsewhere	0.649	0.351	0.000
J31.2 Chronic pharyngitis	0.000	0.353	0.647
J31.1 Chronic nasopharyngitis	0.000	0.353	0.647
G60 Hereditary and idiopathic neuropathy	0.647	0.353	0.000
F45.9 Somatoform disorder, unspecified	0.645	0.355	0.000
F45.4 Persistent somatoform pain disorder	0.645	0.355	0.000
F45.3 Somatoform autonomic dysfunction	0.645	0.355	0.000
F45.2 Hypochondriacal disorder	0.645	0.355	0.000
F45.1 Undifferentiated somatoform disorder	0.645	0.355	0.000
F45.0 Somatisation disorder	0.645	0.355	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.644	0.355	0.000
G90 Disorders of autonomic nervous system	0.644	0.356	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.643	0.357	0.000
G62 Other polyneuropathies	0.643	0.357	0.000
F44.9 Dissociative [conversion] disorder, unspecified	0.643	0.357	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.643	0.357	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.642	0.358	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.642	0.358	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.642	0.358	0.000
G45.0 Vertebro-basilar artery syndrome	0.642	0.358	0.000
E06.3 Autoimmune thyroiditis	0.000	0.359	0.641
W50-W64 Exposure to animate mechanical forces	0.641	0.359	0.000
Q61 Cystic kidney disease	0.641	0.359	0.000
Q53 Undescended testicle	0.639	0.361	0.000
L20-L30 Dermatitis and eczema	0.638	0.362	0.000
W25 Contact with sharp glass	0.638	0.362	0.000
X50-X57 Overexertion, travel and privation	0.636	0.364	0.000
G72 Other myopathies	0.636	0.364	0.000
G56.1 Other lesions of median nerve	0.636	0.364	0.000
B65-B83 Helminthiases	0.635	0.365	0.000
T23 Burn and corrosion of wrist and hand	0.635	0.365	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.634	0.366	0.000
M94 Other disorders of cartilage	0.634	0.366	0.000
K90.9 Intestinal malabsorption, unspecified	0.031	0.367	0.602
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.633	0.367	0.000
F43 Reaction to severe stress, and adjustment disorders	0.633	0.367	0.000
G93 Other disorders of brain	0.633	0.367	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.632	0.368	0.000
E10.1 With ketoacidosis	0.003	0.369	0.627
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.369	0.630
X58-X59 Accidental exposure to other and unspecified factors	0.630	0.370	0.000
S32.40 Fracture of acetabulum (closed)	0.630	0.370	0.000
G96.0 Cerebrospinal fluid leak	0.628	0.372	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.628	0.372	0.000
M86-M90 Other osteopathies	0.627	0.372	0.001
G51.3 Clonic hemifacial spasm	0.627	0.373	0.000
S19 Other and unspecified injuries of neck	0.627	0.373	0.000
M06 Other rheumatoid arthritis	0.478	0.375	0.147
F42.9 Obsessive-compulsive disorder, unspecified	0.625	0.375	0.000
Q28 Other congenital malformations of circulatory system	0.622	0.378	0.000
Q27 Other congenital malformations of peripheral vascular system	0.622	0.378	0.000
Q26 Congenital malformations of great veins	0.622	0.378	0.000
Q25 Congenital malformations of great arteries	0.622	0.378	0.000
Q24 Other congenital malformations of heart	0.622	0.378	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.622	0.378	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.622	0.378	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.378	0.622
U80.1 Methicillin resistant agent	0.622	0.378	0.000
J34.1 Cyst and mucocele of nose and nasal sinus	0.000	0.378	0.622
F32.3 Severe depressive episode with psychotic symptoms	0.621	0.378	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.621	0.379	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.621	0.379	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.621	0.379	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.621	0.379	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.621	0.379	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.621	0.379	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.621	0.379	0.000
T44.0 Anticholinesterase agents	0.621	0.379	0.000
F40.2 Specific (isolated) phobias	0.620	0.380	0.000
C64-C68 Malignant neoplasms of urinary tract	0.620	0.380	0.000
F30.8 Other manic episodes	0.619	0.380	0.000
F30.2 Mania with psychotic symptoms	0.619	0.380	0.000
F30.1 Mania without psychotic symptoms	0.619	0.380	0.000
T50.8 Diagnostic agents	0.619	0.380	0.000
T50.7 Analeptics and opioid receptor antagonists	0.619	0.380	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.619	0.380	0.000
T50.5 Appetite depressants	0.619	0.380	0.000
T50.4 Drugs affecting uric acid metabolism	0.619	0.380	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.619	0.380	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.619	0.380	0.000
T50.1 Loop [high-ceiling] diuretics	0.619	0.380	0.000
T50.0 Mineralocorticoids and their antagonists	0.619	0.380	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.619	0.381	0.000
G56.2 Lesion of ulnar nerve	0.619	0.381	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.617	0.382	0.000
G91 Hydrocephalus	0.617	0.383	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations