TreeWAS – Variant ID: rs28752923

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
R31 Unspecified haematuria	1.000	0.000	0.000
E03 Other hypothyroidism	0.000	0.001	0.999
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.003	0.997
L40.0 Psoriasis vulgaris	0.997	0.003	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.003	0.997
E00-E07 Disorders of thyroid gland	0.000	0.003	0.997
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.015	0.985
M45 Ankylosing spondylitis	0.968	0.032	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.959	0.041	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.093	0.907
L40.4 Guttate psoriasis	0.906	0.094	0.000
E07 Other disorders of thyroid	0.000	0.123	0.877
M07.3 Other psoriatic arthropathies	0.865	0.135	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.857	0.143	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.850	0.150	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.152	0.848
M07.36 Other psoriatic arthropathies (Lower leg)	0.806	0.194	0.000
E03.8 Other specified hypothyroidism	0.000	0.197	0.803
K90 Intestinal malabsorption	0.000	0.198	0.802
G35 Multiple sclerosis	0.000	0.206	0.794
E07.8 Other specified disorders of thyroid	0.000	0.216	0.784
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.784	0.216	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.780	0.220	0.000
L40.8 Other psoriasis	0.777	0.223	0.000
L40.1 Generalised pustular psoriasis	0.760	0.240	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.277	0.723
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.280	0.720
M07.34 Other psoriatic arthropathies (Hand)	0.718	0.282	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E03.5 Myxoedema coma	0.000	0.284	0.716
E03.4 Atrophy of thyroid (acquired)	0.000	0.284	0.716
E03.3 Postinfectious hypothyroidism	0.000	0.284	0.716
E05.5 Thyroid crisis or storm	0.000	0.285	0.715
E05.4 Thyrotoxicosis factitia	0.000	0.285	0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.285	0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.285	0.714
E00 Congenital iodine-deficiency syndrome	0.000	0.285	0.714
M07.38 Other psoriatic arthropathies (Other)	0.714	0.286	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.699	0.301	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.694	0.306	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.694	0.306	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.694	0.306	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.694	0.306	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.694	0.306	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.694	0.306	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.671	0.329	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.343	0.656
E03.1 Congenital hypothyroidism without goitre	0.000	0.349	0.651
E07.9 Disorder of thyroid, unspecified	0.000	0.351	0.649
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.647	0.353	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.356	0.644
L40.3 Pustulosis palmaris et plantaris	0.639	0.361	0.000
E07.1 Dyshormogenetic goitre	0.000	0.371	0.629
E07.0 Hypersecretion of calcitonin	0.000	0.371	0.629
K90.8 Other intestinal malabsorption	0.000	0.375	0.625
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.379	0.621
M07.33 Other psoriatic arthropathies (Forearm)	0.620	0.380	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.620	0.380	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.425	0.575
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.425	0.575
K90.1 Tropical sprue	0.000	0.425	0.575
E05.8 Other thyrotoxicosis	0.000	0.429	0.570
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.488	0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.488	0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.488	0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.488	0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.488	0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.488	0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.488	0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.488	0.512
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.491	0.509
L40-L45 Papulosquamous disorders	0.469	0.531	0.000
E06 Thyroiditis	0.000	0.573	0.427
M07 Psoriatic and enteropathic arthropathies	0.413	0.587	0.000
L41 Parapsoriasis	0.367	0.633	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.642	0.358
L42 Pityriasis rosea	0.356	0.644	0.000
L44 Other papulosquamous disorders	0.339	0.661	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.336	0.663	0.000
E06.3 Autoimmune thyroiditis	0.000	0.666	0.334
E06.4 Drug-induced thyroiditis	0.000	0.694	0.306
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.694	0.306
E06.0 Acute thyroiditis	0.000	0.694	0.306
L43 Lichen planus	0.302	0.698	0.000
M07.5 Arthropathy in ulcerative colitis	0.296	0.704	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.296	0.704	0.000
M07.2 Psoriatic spondylitis	0.296	0.704	0.000
M07.1 Arthritis mutilans	0.296	0.704	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.296	0.704	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.706	0.294
L41.1 Pityriasis lichenoides chronica	0.294	0.706	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.718	0.282
M07.6 Other enteropathic arthropathies	0.274	0.726	0.000
E06.5 Other chronic thyroiditis	0.001	0.736	0.263
L41.9 Parapsoriasis, unspecified	0.263	0.737	0.000
L41.8 Other parapsoriasis	0.263	0.737	0.000
L41.5 Retiform parapsoriasis	0.263	0.737	0.000
L41.4 Large plaque parapsoriasis	0.263	0.737	0.000
L41.3 Small plaque parapsoriasis	0.263	0.737	0.000
L41.2 Lymphomatoid papulosis	0.263	0.737	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.263	0.737	0.000
G36 Other acute disseminated demyelination	0.000	0.738	0.262
L44.0 Pityriasis rubra pilaris	0.245	0.754	0.000
L44.9 Papulosquamous disorder, unspecified	0.243	0.757	0.000
L44.8 Other specified papulosquamous disorders	0.243	0.757	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.243	0.757	0.000
L44.3 Lichen ruber moniliformis	0.243	0.757	0.000
L44.2 Lichen striatus	0.243	0.757	0.000
L44.1 Lichen nitidus	0.243	0.757	0.000
E27 Other disorders of adrenal gland	0.000	0.761	0.239
L43.8 Other lichen planus	0.222	0.778	0.000
L43.3 Subacute (active) lichen planus	0.216	0.784	0.000
L43.2 Lichenoid drug reaction	0.216	0.784	0.000
L43.1 Bullous lichen planus	0.216	0.784	0.000
E06.1 Subacute thyroiditis	0.001	0.785	0.214
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.212	0.787	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.212	0.787	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.212	0.787	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.212	0.787	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.212	0.787	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.212	0.787	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.212	0.787	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.212	0.787	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.212	0.787	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.212	0.787	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.212	0.787	0.000
M07.18 Arthritis mutilans (Other)	0.212	0.787	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.212	0.787	0.000
M07.16 Arthritis mutilans (Lower leg)	0.212	0.787	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.212	0.787	0.000
M07.14 Arthritis mutilans (Hand)	0.212	0.787	0.000
M07.13 Arthritis mutilans (Forearm)	0.212	0.787	0.000
M07.12 Arthritis mutilans (Upper arm)	0.212	0.787	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.212	0.787	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.212	0.787	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.212	0.787	0.000
M07.28 Psoriatic spondylitis (Other)	0.212	0.787	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.212	0.787	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.212	0.787	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.212	0.787	0.000
M07.24 Psoriatic spondylitis (Hand)	0.212	0.787	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.212	0.787	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.212	0.787	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.212	0.787	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.212	0.787	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.212	0.787	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.212	0.787	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.212	0.787	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.212	0.787	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.212	0.787	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.212	0.787	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.212	0.787	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.212	0.787	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.212	0.787	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.212	0.787	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.212	0.787	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.212	0.787	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.212	0.787	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.212	0.787	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.212	0.787	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.212	0.787	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.212	0.787	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.212	0.787	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.212	0.787	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.212	0.787	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.790	0.210
G30-G32 Other degenerative diseases of the nervous system	0.000	0.791	0.209
E04 Other non-toxic goitre	0.000	0.793	0.207
E27.2 Addisonian crisis	0.000	0.794	0.206
L43.0 Hypertrophic lichen planus	0.205	0.795	0.000
Chapter VI Diseases of the nervous system	0.000	0.795	0.205
E06.9 Thyroiditis, unspecified	0.001	0.796	0.203
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.797	0.203
G31.2 Degeneration of nervous system due to alcohol	0.000	0.797	0.203
E20-E35 Disorders of other endocrine glands	0.000	0.801	0.199
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.803	0.197
M07.68 Other enteropathic arthropathies (Other)	0.196	0.803	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.196	0.803	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.196	0.803	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.196	0.803	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.196	0.803	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.196	0.803	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.196	0.803	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.196	0.803	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.196	0.803	0.000
G36.0 Neuromyelitis optica [Devic]	0.000	0.806	0.194
G36.9 Acute disseminated demyelination, unspecified	0.000	0.812	0.188
G36.8 Other specified acute disseminated demyelination	0.000	0.812	0.188
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.812	0.188
L43.9 Lichen planus, unspecified	0.188	0.812	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.813	0.187
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.814	0.186
G70-G73 Diseases of myoneural junction and muscle	0.000	0.816	0.184
G72 Other myopathies	0.000	0.821	0.179
E28 Ovarian dysfunction	0.000	0.822	0.178
M07.69 Other enteropathic arthropathies (Site unspecified)	0.174	0.826	0.000
G30 Alzheimer's disease	0.000	0.826	0.174
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.827	0.173
E20 Hypoparathyroidism	0.000	0.827	0.173
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.828	0.172
E27.5 Adrenomedullary hyperfunction	0.000	0.828	0.172
E27.0 Other adrenocortical overactivity	0.000	0.828	0.172
G72.9 Myopathy, unspecified	0.000	0.832	0.168
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.834	0.166
E04.0 Non-toxic diffuse goitre	0.000	0.834	0.166
G31.8 Other specified degenerative diseases of nervous system	0.000	0.835	0.165
E28.3 Primary ovarian failure	0.000	0.836	0.164
D69 Purpura and other haemorrhagic conditions	0.000	0.839	0.161
E27.8 Other specified disorders of adrenal gland	0.000	0.839	0.161
G00 Bacterial meningitis, not elsewhere classified	0.000	0.844	0.156
G31.0 Circumscribed brain atrophy	0.000	0.845	0.154
E20.9 Hypoparathyroidism, unspecified	0.000	0.846	0.154
G72.8 Other specified myopathies	0.000	0.849	0.151
G06 Intracranial and intraspinal abscess and granuloma	0.000	0.849	0.151
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.850	0.150
E04.8 Other specified non-toxic goitre	0.000	0.852	0.148
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.852	0.148
G30.0 Alzheimer's disease with early onset	0.000	0.855	0.145
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.857	0.143
E32 Diseases of thymus	0.000	0.857	0.143
E31 Polyglandular dysfunction	0.000	0.857	0.143
E30 Disorders of puberty, not elsewhere classified	0.000	0.857	0.143
G72.1 Alcoholic myopathy	0.000	0.857	0.143
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.858	0.142
G82 Paraplegia and tetraplegia	0.000	0.858	0.142
M05-M14 Inflammatory polyarthropathies	0.141	0.859	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.860	0.140
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.000	0.861	0.139
G72.0 Drug-induced myopathy	0.000	0.861	0.139
G82.1 Spastic paraplegia	0.000	0.864	0.136
M35 Other systemic involvement of connective tissue	0.000	0.864	0.136
D69.4 Other primary thrombocytopenia	0.000	0.865	0.135
E24 Cushing's syndrome	0.000	0.865	0.135
M05 Seropositive rheumatoid arthritis	0.134	0.866	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.000	0.866	0.134
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.000	0.866	0.134
G00.9 Bacterial meningitis, unspecified	0.000	0.868	0.132
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.000	0.868	0.132
G30.1 Alzheimer's disease with late onset	0.000	0.868	0.132
G01 Meningitis in bacterial diseases classified elsewhere	0.000	0.869	0.131
G83 Other paralytic syndromes	0.000	0.869	0.130
G03 Meningitis due to other and unspecified causes	0.000	0.870	0.130
E25 Adrenogenital disorders	0.000	0.870	0.130
G30.8 Other Alzheimer's disease	0.000	0.870	0.130
E28.2 Polycystic ovarian syndrome	0.000	0.870	0.129
D69.5 Secondary thrombocytopenia	0.000	0.871	0.129
M05.9 Seropositive rheumatoid arthritis, unspecified	0.129	0.871	0.000
G72.3 Periodic paralysis	0.000	0.871	0.128
G72.2 Myopathy due to other toxic agents	0.000	0.871	0.128
E28.9 Ovarian dysfunction, unspecified	0.000	0.872	0.128
E28.8 Other ovarian dysfunction	0.000	0.872	0.128
E28.1 Androgen excess	0.000	0.872	0.128
E28.0 Oestrogen excess	0.000	0.872	0.128
G06.1 Intraspinal abscess and granuloma	0.000	0.872	0.128
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.872	0.127
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.000	0.873	0.127
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.874	0.126
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.875	0.124
E20.8 Other hypoparathyroidism	0.000	0.876	0.124
E20.1 Pseudohypoparathyroidism	0.000	0.876	0.124
E20.0 Idiopathic hypoparathyroidism	0.000	0.876	0.124
G83.4 Cauda equina syndrome	0.000	0.877	0.123
E23 Hypofunction and other disorders of pituitary gland	0.000	0.878	0.122
D69.2 Other nonthrombocytopenic purpura	0.000	0.878	0.122
G30.9 Alzheimer's disease, unspecified	0.000	0.880	0.120
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.117	0.883	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.000	0.883	0.117
D69.8 Other specified haemorrhagic conditions	0.000	0.884	0.116
D69.0 Allergic purpura	0.000	0.885	0.115
G00.1 Pneumococcal meningitis	0.000	0.886	0.114
G06.0 Intracranial abscess and granuloma	0.000	0.887	0.113
G00.8 Other bacterial meningitis	0.000	0.888	0.112
G00.3 Staphylococcal meningitis	0.000	0.888	0.112
G00.2 Streptococcal meningitis	0.000	0.888	0.112
G00.0 Haemophilus meningitis	0.000	0.888	0.112
E40-E46 Malnutrition	0.000	0.889	0.111
G81 Hemiplegia	0.000	0.889	0.111
D69.1 Qualitative platelet defects	0.000	0.889	0.110
E29 Testicular dysfunction	0.000	0.890	0.110
E24.2 Drug-induced Cushing's syndrome	0.000	0.890	0.110
G82.5 Tetraplegia, unspecified	0.000	0.891	0.109
E27.9 Disorder of adrenal gland, unspecified	0.000	0.891	0.109
G83.9 Paralytic syndrome, unspecified	0.000	0.892	0.108
E26 Hyperaldosteronism	0.000	0.892	0.108
G80 Infantile cerebral palsy	0.000	0.892	0.108
E23.2 Diabetes insipidus	0.000	0.893	0.107
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.107	0.893	0.000
G71 Primary disorders of muscles	0.000	0.893	0.107
G82.4 Spastic tetraplegia	0.000	0.893	0.107
G02.0 Meningitis in viral diseases classified elsewhere	0.000	0.894	0.105
M05.1 Rheumatoid lung disease	0.105	0.895	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.104	0.896	0.000
M08 Juvenile arthritis	0.104	0.896	0.000
M12 Other specific arthropathies	0.104	0.896	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.897	0.103
R94.3 Abnormal results of cardiovascular function studies	0.000	0.897	0.103
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.897	0.103
E30.9 Disorder of puberty, unspecified	0.000	0.897	0.102
E30.8 Other disorders of puberty	0.000	0.897	0.102
E30.1 Precocious puberty	0.000	0.897	0.102
E30.0 Delayed puberty	0.000	0.897	0.102
E31.9 Polyglandular dysfunction, unspecified	0.000	0.897	0.102
E31.8 Other polyglandular dysfunction	0.000	0.897	0.102
E31.1 Polyglandular hyperfunction	0.000	0.897	0.102
E31.0 Autoimmune polyglandular failure	0.000	0.897	0.102
E32.9 Disease of thymus, unspecified	0.000	0.897	0.102
E32.8 Other diseases of thymus	0.000	0.897	0.102
E32.1 Abscess of thymus	0.000	0.897	0.102
E32.0 Persistent hyperplasia of thymus	0.000	0.897	0.102
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.897	0.102
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.897	0.102
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.897	0.102
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.898	0.102
E15 Nondiabetic hypoglycaemic coma	0.000	0.898	0.102
G82.3 Flaccid tetraplegia	0.000	0.898	0.102
E34 Other endocrine disorders	0.000	0.898	0.102
E24.8 Other Cushing's syndrome	0.000	0.898	0.102
M09 Juvenile arthritis in diseases classified elsewhere	0.101	0.899	0.000
E50-E64 Other nutritional deficiencies	0.000	0.899	0.101
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.101	0.899	0.000
G37.5 Concentric sclerosis [Balo]	0.000	0.899	0.100
G37.4 Subacute necrotising myelitis	0.000	0.899	0.100
G37.2 Central pontine myelinolysis	0.000	0.899	0.100
G37.1 Central demyelination of corpus callosum	0.000	0.899	0.100
G37.0 Diffuse sclerosis	0.000	0.899	0.100
G12 Spinal muscular atrophy and related syndromes	0.000	0.900	0.100
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.000	0.900	0.100
G02.1 Meningitis in mycoses	0.000	0.900	0.100
G70 Myasthenia gravis and other myoneural disorders	0.000	0.901	0.099
G06.2 Extradural and subdural abscess, unspecified	0.000	0.901	0.099
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.098	0.902	0.000
M35.8 Other specified systemic involvement of connective tissue	0.000	0.902	0.098
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.903	0.097
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.903	0.097
M35.5 Multifocal fibrosclerosis	0.000	0.903	0.097
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.903	0.097
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.097	0.903	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.903	0.097
E24.3 Ectopic ACTH syndrome	0.000	0.903	0.097
E24.1 Nelson's syndrome	0.000	0.903	0.097
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.097	0.903	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.096	0.904	0.000
M05.0 Felty's syndrome	0.096	0.904	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.000	0.904	0.096
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.000	0.904	0.096
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.000	0.904	0.096
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.904	0.096
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.904	0.096
M14 Arthropathies in other diseases classified elsewhere	0.095	0.905	0.000
G73.7 Myopathy other diseases classified elsewhere	0.000	0.905	0.095
G73.6 Myopathy in metabolic diseases	0.000	0.905	0.095
G73.5 Myopathy in endocrine diseases	0.000	0.905	0.095
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.000	0.905	0.095
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.000	0.905	0.095
G73.2 Other myasthenic syndromes in neoplastic disease	0.000	0.905	0.095
G73.1 Eaton-Lambert syndrome	0.000	0.905	0.095
G73.0 Myasthenic syndromes in endocrine diseases	0.000	0.905	0.095
M35.7 Hypermobility syndrome	0.000	0.905	0.095
M35.2 Behcet's disease	0.000	0.905	0.094
G83.5 Locked-in syndrome	0.000	0.906	0.094
G83.0 Diplegia of upper limbs	0.000	0.906	0.094
M05.8 Other seropositive rheumatoid arthritis	0.094	0.906	0.000
G03.8 Meningitis due to other specified causes	0.000	0.906	0.093
G03.2 Benign recurrent meningitis [Mollaret]	0.000	0.906	0.093
G03.1 Chronic meningitis	0.000	0.906	0.093
G03.0 Nonpyogenic meningitis	0.000	0.906	0.093
E25.9 Adrenogenital disorder, unspecified	0.000	0.907	0.093
E25.8 Other adrenogenital disorders	0.000	0.907	0.093
G82.0 Flaccid paraplegia	0.000	0.907	0.093
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.092	0.907	0.000
G83.1 Monoplegia of lower limb	0.000	0.908	0.092
M05.2 Rheumatoid vasculitis	0.091	0.909	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.910	0.090
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.090	0.910	0.000
G03.9 Meningitis, unspecified	0.000	0.910	0.090
G11 Hereditary ataxia	0.000	0.910	0.090
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.911	0.089
E24.0 Pituitary-dependent Cushing's disease	0.000	0.911	0.089
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.912	0.088
E23.1 Drug-induced hypopituitarism	0.000	0.912	0.088
E23.6 Other disorders of pituitary gland	0.000	0.912	0.088
G10 Huntington's disease	0.000	0.914	0.086
G81.1 Spastic hemiplegia	0.000	0.914	0.086
G14 Postpolio syndrome	0.000	0.915	0.085
M11 Other crystal arthropathies	0.085	0.915	0.000
G80.0 Spastic cerebral palsy	0.000	0.916	0.084
E34.8 Other specified endocrine disorders	0.000	0.917	0.083
D69.9 Haemorrhagic condition, unspecified	0.000	0.917	0.083
E53 Deficiency of other B group vitamins	0.000	0.917	0.083
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.917	0.083
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.917	0.082
G83.3 Monoplegia, unspecified	0.000	0.917	0.082
M06 Other rheumatoid arthritis	0.082	0.918	0.000
M35.1 Other overlap syndromes	0.000	0.918	0.082
E51 Thiamine deficiency	0.000	0.918	0.082
M13 Other arthritis	0.082	0.918	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.081	0.919	0.000
M12.2 Villonodular synovitis (pigmented)	0.081	0.919	0.000
G12.2 Motor neuron disease	0.000	0.919	0.081
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.920	0.080
G80.8 Other infantile cerebral palsy	0.000	0.920	0.080
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.920	0.080
E45 Retarded development following protein-energy malnutrition	0.000	0.920	0.080
E43 Unspecified severe protein-energy malnutrition	0.000	0.920	0.080
E42 Marasmic kwashiorkor	0.000	0.920	0.080
E41 Nutritional marasmus	0.000	0.920	0.080
E40 Kwashiorkor	0.000	0.920	0.080
G81.0 Flaccid hemiplegia	0.000	0.920	0.080
E29.8 Other testicular dysfunction	0.000	0.921	0.079
E29.0 Testicular hyperfunction	0.000	0.921	0.079
M05.10 Rheumatoid lung disease (Multiple sites)	0.078	0.922	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.078	0.922	0.000
G80.2 Infantile hemiplegia	0.000	0.922	0.078
E26.8 Other hyperaldosteronism	0.000	0.922	0.077
E26.1 Secondary hyperaldosteronism	0.000	0.922	0.077
G80.4 Ataxic cerebral palsy	0.000	0.922	0.077
G80.3 Dyskinetic cerebral palsy	0.000	0.922	0.077
M08.0 Juvenile rheumatoid arthritis	0.077	0.922	0.000
G71.9 Primary disorder of muscle, unspecified	0.000	0.923	0.077
G71.8 Other primary disorders of muscles	0.000	0.923	0.077
G71.2 Congenital myopathies	0.000	0.923	0.077
E04.2 Non-toxic multinodular goitre	0.000	0.923	0.077
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.000	0.925	0.075
M05.18 Rheumatoid lung disease (Other)	0.075	0.925	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.075	0.925	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.075	0.925	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.075	0.925	0.000
M05.14 Rheumatoid lung disease (Hand)	0.075	0.925	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.075	0.925	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.075	0.925	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.075	0.925	0.000
G62 Other polyneuropathies	0.000	0.925	0.075
M08.9 Juvenile arthritis, unspecified	0.075	0.925	0.000
M08.8 Other juvenile arthritis	0.075	0.925	0.000
M08.4 Pauciarticular juvenile arthritis	0.075	0.925	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.075	0.925	0.000
M08.2 Juvenile arthritis with systemic onset	0.075	0.925	0.000
M08.1 Juvenile ankylosing spondylitis	0.075	0.925	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.075	0.925	0.000
M12.4 Intermittent hydrarthrosis	0.075	0.925	0.000
M12.1 Kaschin-Beck disease	0.075	0.925	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.075	0.925	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.925	0.074
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.926	0.074
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.926	0.074
E16.4 Abnormal secretion of gastrin	0.000	0.926	0.074
E16.3 Increased secretion of glucagon	0.000	0.926	0.074
G80.1 Spastic diplegia	0.000	0.926	0.074
E34.5 Androgen resistance syndrome	0.000	0.926	0.073
E34.4 Constitutional tall stature	0.000	0.926	0.073
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.926	0.073
E34.1 Other hypersecretion of intestinal hormones	0.000	0.926	0.073
M12.3 Palindromic rheumatism	0.073	0.926	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.927	0.073
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.073	0.927	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.073	0.927	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.073	0.927	0.000
M09.0 Juvenile arthritis in psoriasis	0.073	0.927	0.000
E22 Hyperfunction of pituitary gland	0.000	0.927	0.073
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.927	0.072
E50 Vitamin A deficiency	0.000	0.927	0.072
E60 Dietary zinc deficiency	0.000	0.927	0.072
E59 Dietary selenium deficiency	0.000	0.927	0.072
E52 Niacin deficiency [pellagra]	0.000	0.927	0.072
G12.9 Spinal muscular atrophy, unspecified	0.000	0.928	0.072
G12.8 Other spinal muscular atrophies and related syndromes	0.000	0.928	0.072
G12.1 Other inherited spinal muscular atrophy	0.000	0.928	0.072
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.000	0.928	0.072
G71.1 Myotonic disorders	0.000	0.928	0.072
M06.3 Rheumatoid nodule	0.072	0.928	0.000
M12.5 Traumatic arthropathy	0.071	0.929	0.000
G70.8 Other specified myoneural disorders	0.000	0.929	0.071
G70.2 Congenital and developmental myasthenia	0.000	0.929	0.071
G70.1 Toxic myoneural disorders	0.000	0.929	0.071
E53.8 Deficiency of other specified B group vitamins	0.000	0.929	0.071
E16.2 Hypoglycaemia, unspecified	0.000	0.929	0.071
E63 Other nutritional deficiencies	0.000	0.929	0.071
E24.9 Cushing's syndrome, unspecified	0.000	0.930	0.070
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.930	0.070
G70.9 Myoneural disorder, unspecified	0.000	0.930	0.070
E56 Other vitamin deficiencies	0.000	0.930	0.070
M05.09 Felty's syndrome (Site unspecified)	0.069	0.931	0.000
M05.08 Felty's syndrome (Other)	0.069	0.931	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.069	0.931	0.000
M05.06 Felty's syndrome (Lower leg)	0.069	0.931	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.069	0.931	0.000
M05.04 Felty's syndrome (Hand)	0.069	0.931	0.000
M05.03 Felty's syndrome (Forearm)	0.069	0.931	0.000
M05.02 Felty's syndrome (Upper arm)	0.069	0.931	0.000
M05.01 Felty's syndrome (Shoulder region)	0.069	0.931	0.000
M05.00 Felty's syndrome (Multiple sites)	0.069	0.931	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.069	0.931	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.069	0.931	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.069	0.931	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations