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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28894977
log Bayes Factor = 91.6864
Chromosome 6   position 31,003,701  (GRCh37) Explore rs28894977 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
L40.0 Psoriasis vulgaris
0.997 0.003 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.989 0.011 0.000
M07.3 Other psoriatic arthropathies
0.985 0.015 0.000
E03 Other hypothyroidism
0.000 0.018 0.982
M07.30 Other psoriatic arthropathies (Multiple sites)
0.977 0.023 0.000
E00-E07 Disorders of thyroid gland
0.000 0.028 0.972
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.033 0.967
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.054 0.946
E05.9 Thyrotoxicosis, unspecified
0.000 0.071 0.929
M07.34 Other psoriatic arthropathies (Hand)
0.856 0.144 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.853 0.147 0.000
L40.1 Generalised pustular psoriasis
0.836 0.164 0.000
E07 Other disorders of thyroid
0.000 0.164 0.836
L40.8 Other psoriasis
0.822 0.178 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.793 0.207 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.240 0.760
E10.9 Without complications
0.000 0.271 0.729
E10 Insulin-dependent diabetes mellitus
0.000 0.273 0.727
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E10-E14 Diabetes mellitus
0.000 0.290 0.710
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.291 0.709
M07.38 Other psoriatic arthropathies (Other)
0.706 0.293 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.706 0.293 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.706 0.293 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.706 0.293 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.706 0.293 0.000
E03.5 Myxoedema coma
0.000 0.296 0.704
E03.4 Atrophy of thyroid (acquired)
0.000 0.296 0.704
E03.3 Postinfectious hypothyroidism
0.000 0.296 0.704
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.296 0.704
E03.1 Congenital hypothyroidism without goitre
0.000 0.296 0.704
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.296 0.704
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.303 0.697
E00 Congenital iodine-deficiency syndrome
0.000 0.303 0.697
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.303 0.697
E05.8 Other thyrotoxicosis
0.000 0.307 0.693
E05.5 Thyroid crisis or storm
0.000 0.307 0.693
E05.4 Thyrotoxicosis factitia
0.000 0.307 0.693
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.307 0.693
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.307 0.693
E06 Thyroiditis
0.000 0.334 0.666
E10.4 With neurological complications
0.000 0.352 0.648
E03.8 Other specified hypothyroidism
0.000 0.395 0.605
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.398 0.602
E07.1 Dyshormogenetic goitre
0.000 0.401 0.599
E07.0 Hypersecretion of calcitonin
0.000 0.401 0.599
E10.3 With ophthalmic complications
0.000 0.405 0.595
E10.5 With peripheral circulatory complications
0.000 0.442 0.558
E10.1 With ketoacidosis
0.000 0.447 0.552
E14 Unspecified diabetes mellitus
0.000 0.452 0.548
E07.8 Other specified disorders of thyroid
0.000 0.467 0.533
E10.7 With multiple complications
0.000 0.479 0.521
E10.6 With other specified complications
0.000 0.479 0.521
E10.2 With renal complications
0.000 0.479 0.521
E10.0 With coma
0.000 0.479 0.521
K90 Intestinal malabsorption
0.000 0.485 0.515
E12 Malnutrition-related diabetes mellitus
0.000 0.491 0.509
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.500 0.500
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.500 0.500
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.500 0.500
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.500 0.500
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.500 0.500
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.500 0.500
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.500 0.500
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.500 0.500
E10.8 With unspecified complications
0.000 0.507 0.493
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.515 0.485
E13 Other specified diabetes mellitus
0.000 0.516 0.484
E50-E64 Other nutritional deficiencies
0.000 0.519 0.481
E06.5 Other chronic thyroiditis
0.000 0.523 0.477
E06.4 Drug-induced thyroiditis
0.000 0.523 0.477
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.523 0.477
E06.1 Subacute thyroiditis
0.000 0.523 0.477
E06.0 Acute thyroiditis
0.000 0.523 0.477
E06.9 Thyroiditis, unspecified
0.000 0.525 0.475
E40-E46 Malnutrition
0.000 0.542 0.458
E14.9 Without complications
0.000 0.545 0.455
E06.3 Autoimmune thyroiditis
0.000 0.551 0.449
M07 Psoriatic and enteropathic arthropathies
0.428 0.572 0.000
E14.3 With ophthalmic complications
0.000 0.590 0.410
K90.9 Intestinal malabsorption, unspecified
0.000 0.603 0.396
E14.8 With unspecified complications
0.000 0.607 0.393
E14.7 With multiple complications
0.000 0.607 0.393
E14.6 With other specified complications
0.000 0.607 0.393
E14.5 With peripheral circulatory complications
0.000 0.607 0.393
E14.2 Withrenal complications
0.000 0.607 0.393
E14.1 With ketoacidosis
0.000 0.607 0.393
E14.0 With coma
0.000 0.607 0.393
E65-E68 Obesity and other hyperalimentation
0.000 0.617 0.383
K90.8 Other intestinal malabsorption
0.000 0.630 0.369
K90.3 Pancreatic steatorrhoea
0.000 0.630 0.369
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.630 0.369
K90.1 Tropical sprue
0.000 0.630 0.369
E55 Vitamin D deficiency
0.000 0.632 0.368
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.633 0.367
E12.9 Without complications
0.000 0.635 0.365
E12.8 With unspecified complications
0.000 0.635 0.365
E12.7 With multiple complications
0.000 0.635 0.365
E12.6 With other specified complications
0.000 0.635 0.365
E12.5 With peripheral circulatory complications
0.000 0.635 0.365
E12.4 With neurological complications
0.000 0.635 0.365
E12.3 With ophthalmic complications
0.000 0.635 0.365
E12.2 With renal complications
0.000 0.635 0.365
E12.1 With ketoacidosis
0.000 0.635 0.365
E12.0 With coma
0.000 0.635 0.365
L40-L45 Papulosquamous disorders
0.362 0.638 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.652 0.348
E13.8 With unspecified complications
0.000 0.653 0.347
E13.7 With multiple complications
0.000 0.653 0.347
E13.6 With other specified complications
0.000 0.653 0.347
E13.5 With peripheral circulatory complications
0.000 0.653 0.347
E13.4 With neurological complications
0.000 0.653 0.347
E13.3 With ophthalmic complications
0.000 0.653 0.347
E13.2 With renal complications
0.000 0.653 0.347
E13.1 With ketoacidosis
0.000 0.653 0.347
E13.0 With coma
0.000 0.653 0.347
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.655 0.345
E63 Other nutritional deficiencies
0.000 0.655 0.345
E56 Other vitamin deficiencies
0.000 0.655 0.345
E51 Thiamine deficiency
0.000 0.655 0.345
E50 Vitamin A deficiency
0.000 0.655 0.345
E60 Dietary zinc deficiency
0.000 0.655 0.345
E59 Dietary selenium deficiency
0.000 0.655 0.345
E58 Dietary calcium deficiency
0.000 0.655 0.345
E54 Ascorbic acid deficiency
0.000 0.655 0.345
E52 Niacin deficiency [pellagra]
0.000 0.655 0.345
E14.4 With neurological complications
0.000 0.670 0.330
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.671 0.329
E45 Retarded development following protein-energy malnutrition
0.000 0.671 0.329
E43 Unspecified severe protein-energy malnutrition
0.000 0.671 0.329
E42 Marasmic kwashiorkor
0.000 0.671 0.329
E41 Nutritional marasmus
0.000 0.671 0.329
E40 Kwashiorkor
0.000 0.671 0.329
E53 Deficiency of other B group vitamins
0.000 0.674 0.326
E16 Other disorders of pancreatic internal secretion
0.000 0.675 0.325
E13.9 Without complications
0.000 0.678 0.322
E04 Other non-toxic goitre
0.000 0.691 0.309
E61 Deficiency of other nutrient elements
0.000 0.692 0.308
M07.6 Other enteropathic arthropathies
0.307 0.693 0.000
M07.5 Arthropathy in ulcerative colitis
0.307 0.693 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.307 0.693 0.000
M07.2 Psoriatic spondylitis
0.307 0.693 0.000
M07.1 Arthritis mutilans
0.307 0.693 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.307 0.693 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.714 0.286
E20-E35 Disorders of other endocrine glands
0.000 0.715 0.285
L42 Pityriasis rosea
0.282 0.718 0.000
E65 Localised adiposity
0.000 0.721 0.279
E46 Unspecified protein-energy malnutrition
0.000 0.721 0.278
E67 Other hyperalimentation
0.000 0.725 0.275
E68 Sequelae of hyperalimentation
0.000 0.725 0.275
E55.0 Rickets, active
0.000 0.736 0.264
L44 Other papulosquamous disorders
0.260 0.740 0.000
L41 Parapsoriasis
0.260 0.740 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.260 0.740 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.752 0.247
E50.8 Other manifestations of vitamin A deficiency
0.000 0.752 0.247
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.752 0.247
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.752 0.247
E50.5 Vitamin A deficiency with night blindness
0.000 0.752 0.247
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.752 0.247
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.752 0.247
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.752 0.247
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.752 0.247
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.752 0.247
E51.9 Thiamine deficiency, unspecified
0.000 0.752 0.247
E51.8 Other manifestations of thiamine deficiency
0.000 0.752 0.247
E51.2 Wernicke's encephalopathy
0.000 0.752 0.247
E51.1 Beriberi
0.000 0.752 0.247
E56.9 Vitamin deficiency, unspecified
0.000 0.752 0.247
E56.8 Deficiency of other vitamins
0.000 0.752 0.247
E56.1 Deficiency of vitamin K
0.000 0.752 0.247
E56.0 Deficiency of vitamin E
0.000 0.752 0.247
E63.9 Nutritional deficiency, unspecified
0.000 0.752 0.247
E63.8 Other specified nutritional deficiencies
0.000 0.752 0.247
E63.1 Imbalance of constituents of food intake
0.000 0.752 0.247
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.752 0.247
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.752 0.247
E64.8 Sequelae of other nutritional deficiencies
0.000 0.752 0.247
E64.3 Sequelae of rickets
0.000 0.752 0.247
E64.2 Sequelae of vitamin C deficiency
0.000 0.752 0.247
E64.1 Sequelae of vitamin A deficiency
0.000 0.752 0.247
E64.0 Sequelae of protein-energy malnutrition
0.000 0.752 0.247
E04.9 Non-toxic goitre, unspecified
0.000 0.759 0.241
E44.1 Mild protein-energy malnutrition
0.000 0.764 0.236
E44.0 Moderate protein-energy malnutrition
0.000 0.764 0.236
E53.9 Vitamin B deficiency, unspecified
0.000 0.766 0.234
E53.1 Pyridoxine deficiency
0.000 0.766 0.234
E53.0 Riboflavin deficiency
0.000 0.766 0.234
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.767 0.233
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.767 0.233
E16.4 Abnormal secretion of gastrin
0.000 0.767 0.233
E16.3 Increased secretion of glucagon
0.000 0.767 0.233
E16.1 Other hypoglycaemia
0.000 0.767 0.233
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.767 0.233
E27 Other disorders of adrenal gland
0.000 0.777 0.223
E04.8 Other specified non-toxic goitre
0.000 0.778 0.222
E61.9 Deficiency of nutrient element, unspecified
0.000 0.779 0.221
E61.8 Deficiency of other specified nutrient elements
0.000 0.779 0.221
E61.7 Deficiency of multiple nutrient elements
0.000 0.779 0.221
E61.6 Vanadium deficiency
0.000 0.779 0.221
E61.5 Molybdenum deficiency
0.000 0.779 0.221
E61.4 Chromium deficiency
0.000 0.779 0.221
E61.3 Manganese deficiency
0.000 0.779 0.221
E61.2 Magnesium deficiency
0.000 0.779 0.221
E61.0 Copper deficiency
0.000 0.779 0.221
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.220 0.780 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.220 0.780 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.220 0.780 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.220 0.780 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.220 0.780 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.220 0.780 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.220 0.780 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.220 0.780 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.220 0.780 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.220 0.780 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.220 0.780 0.000
M07.18 Arthritis mutilans (Other)
0.220 0.780 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.220 0.780 0.000
M07.16 Arthritis mutilans (Lower leg)
0.220 0.780 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.220 0.780 0.000
M07.14 Arthritis mutilans (Hand)
0.220 0.780 0.000
M07.13 Arthritis mutilans (Forearm)
0.220 0.780 0.000
M07.12 Arthritis mutilans (Upper arm)
0.220 0.780 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.220 0.780 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.220 0.780 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.220 0.780 0.000
M07.28 Psoriatic spondylitis (Other)
0.220 0.780 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.220 0.780 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.220 0.780 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.220 0.780 0.000
M07.24 Psoriatic spondylitis (Hand)
0.220 0.780 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.220 0.780 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.220 0.780 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.220 0.780 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.220 0.780 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.220 0.780 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.220 0.780 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.220 0.780 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.220 0.780 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.220 0.780 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.220 0.780 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.220 0.780 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.220 0.780 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.220 0.780 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.220 0.780 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.220 0.780 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.220 0.780 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.220 0.780 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.220 0.780 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.220 0.780 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.220 0.780 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.220 0.780 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.220 0.780 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.220 0.780 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.220 0.780 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.220 0.780 0.000
M07.68 Other enteropathic arthropathies (Other)
0.220 0.780 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.220 0.780 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.220 0.780 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.220 0.780 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.220 0.780 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.220 0.780 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.220 0.780 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.220 0.780 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.220 0.780 0.000
E29 Testicular dysfunction
0.000 0.780 0.220
E53.8 Deficiency of other specified B group vitamins
0.000 0.784 0.216
E16.2 Hypoglycaemia, unspecified
0.000 0.790 0.210
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.795 0.204
E32 Diseases of thymus
0.000 0.795 0.204
E31 Polyglandular dysfunction
0.000 0.795 0.204
E30 Disorders of puberty, not elsewhere classified
0.000 0.795 0.204
E25 Adrenogenital disorders
0.000 0.795 0.204
E20 Hypoparathyroidism
0.000 0.795 0.204
E34 Other endocrine disorders
0.000 0.796 0.203
E22 Hyperfunction of pituitary gland
0.000 0.798 0.202
E67.8 Other specified hyperalimentation
0.000 0.803 0.197
E67.3 Hypervitaminosis D
0.000 0.803 0.197
E67.2 Megavitamin-B6 syndrome
0.000 0.803 0.197
E67.1 Hypercarotenaemia
0.000 0.803 0.197
E67.0 Hypervitaminosis A
0.000 0.803 0.197
E26 Hyperaldosteronism
0.000 0.804 0.196
L43 Lichen planus
0.188 0.812 0.000
L41.9 Parapsoriasis, unspecified
0.186 0.813 0.000
L41.8 Other parapsoriasis
0.186 0.813 0.000
L41.5 Retiform parapsoriasis
0.186 0.813 0.000
L41.4 Large plaque parapsoriasis
0.186 0.813 0.000
L41.3 Small plaque parapsoriasis
0.186 0.813 0.000
L41.2 Lymphomatoid papulosis
0.186 0.813 0.000
L41.1 Pityriasis lichenoides chronica
0.186 0.813 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.186 0.813 0.000
L44.9 Papulosquamous disorder, unspecified
0.186 0.813 0.000
L44.8 Other specified papulosquamous disorders
0.186 0.813 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.186 0.813 0.000
L44.3 Lichen ruber moniliformis
0.186 0.813 0.000
L44.2 Lichen striatus
0.186 0.813 0.000
L44.1 Lichen nitidus
0.186 0.813 0.000
L44.0 Pityriasis rubra pilaris
0.186 0.813 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.814 0.186
E61.1 Iron deficiency
0.000 0.815 0.184
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.819 0.181
E28 Ovarian dysfunction
0.000 0.823 0.177
E04.0 Non-toxic diffuse goitre
0.001 0.826 0.173
E29.1 Testicular hypofunction
0.000 0.827 0.173
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.828 0.172
E27.8 Other specified disorders of adrenal gland
0.000 0.835 0.165
E27.5 Adrenomedullary hyperfunction
0.000 0.840 0.160
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.840 0.160
E27.0 Other adrenocortical overactivity
0.000 0.840 0.160
E29.9 Testicular dysfunction, unspecified
0.000 0.842 0.158
E29.8 Other testicular dysfunction
0.000 0.842 0.158
E29.0 Testicular hyperfunction
0.000 0.842 0.158
E27.2 Addisonian crisis
0.000 0.851 0.149
E23 Hypofunction and other disorders of pituitary gland
0.000 0.852 0.148
E20.9 Hypoparathyroidism, unspecified
0.000 0.853 0.147
E20.8 Other hypoparathyroidism
0.000 0.853 0.147
E20.1 Pseudohypoparathyroidism
0.000 0.853 0.147
E20.0 Idiopathic hypoparathyroidism
0.000 0.853 0.147
E25.9 Adrenogenital disorder, unspecified
0.000 0.853 0.147
E25.8 Other adrenogenital disorders
0.000 0.853 0.147
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.853 0.147
E30.9 Disorder of puberty, unspecified
0.000 0.853 0.147
E30.8 Other disorders of puberty
0.000 0.853 0.147
E30.1 Precocious puberty
0.000 0.853 0.147
E30.0 Delayed puberty
0.000 0.853 0.147
E31.9 Polyglandular dysfunction, unspecified
0.000 0.853 0.147
E31.8 Other polyglandular dysfunction
0.000 0.853 0.147
E31.1 Polyglandular hyperfunction
0.000 0.853 0.147
E31.0 Autoimmune polyglandular failure
0.000 0.853 0.147
E32.9 Disease of thymus, unspecified
0.000 0.853 0.147
E32.8 Other diseases of thymus
0.000 0.853 0.147
E32.1 Abscess of thymus
0.000 0.853 0.147
E32.0 Persistent hyperplasia of thymus
0.000 0.853 0.147
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.853 0.147
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.853 0.147
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.853 0.147
E34.8 Other specified endocrine disorders
0.000 0.854 0.146
E34.5 Androgen resistance syndrome
0.000 0.854 0.146
E34.4 Constitutional tall stature
0.000 0.854 0.146
E34.3 Short stature, not elsewhere classified
0.000 0.854 0.146
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.854 0.146
E34.1 Other hypersecretion of intestinal hormones
0.000 0.854 0.146
E34.0 Carcinoid syndrome
0.000 0.854 0.146
E22.0 Acromegaly and pituitary gigantism
0.000 0.854 0.145
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.855 0.145
E22.8 Other hyperfunction of pituitary gland
0.000 0.855 0.145
E22.1 Hyperprolactinaemia
0.000 0.855 0.145
E34.9 Endocrine disorder, unspecified
0.000 0.855 0.145
E24 Cushing's syndrome
0.001 0.857 0.142
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.858 0.142
E26.9 Hyperaldosteronism, unspecified
0.000 0.859 0.140
E26.8 Other hyperaldosteronism
0.000 0.859 0.140
E26.1 Secondary hyperaldosteronism
0.000 0.859 0.140
E27.9 Disorder of adrenal gland, unspecified
0.000 0.860 0.140
E66 Obesity
0.000 0.860 0.140
J33 Nasal polyp
0.000 0.864 0.136
E21.0 Primary hyperparathyroidism
0.000 0.864 0.136
J33.9 Nasal polyp, unspecified
0.000 0.865 0.135
L43.8 Other lichen planus
0.135 0.865 0.000
L43.3 Subacute (active) lichen planus
0.135 0.865 0.000
L43.2 Lichenoid drug reaction
0.135 0.865 0.000
L43.1 Bullous lichen planus
0.135 0.865 0.000
L43.0 Hypertrophic lichen planus
0.135 0.865 0.000
J33.0 Polyp of nasal cavity
0.000 0.867 0.133
E26.0 Primary hyperaldosteronism
0.000 0.868 0.132
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.870 0.130
E21.4 Other specified disorders of parathyroid gland
0.000 0.870 0.130
E21.2 Other hyperparathyroidism
0.000 0.870 0.130
J33.8 Other polyp of sinus
0.000 0.870 0.130
E04.1 Non-toxic single thyroid nodule
0.000 0.871 0.128
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.872 0.127
E28.9 Ovarian dysfunction, unspecified
0.000 0.873 0.127
E28.8 Other ovarian dysfunction
0.000 0.873 0.127
E28.3 Primary ovarian failure
0.000 0.873 0.127
E28.1 Androgen excess
0.000 0.873 0.127
E28.0 Oestrogen excess
0.000 0.873 0.127
E04.2 Non-toxic multinodular goitre
0.000 0.880 0.119
E23.2 Diabetes insipidus
0.000 0.880 0.119
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.893 0.106
E23.1 Drug-induced hypopituitarism
0.000 0.893 0.106
E24.8 Other Cushing's syndrome
0.001 0.897 0.102
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.897 0.102
E24.3 Ectopic ACTH syndrome
0.001 0.897 0.102
E24.2 Drug-induced Cushing's syndrome
0.001 0.897 0.102
E24.1 Nelson's syndrome
0.001 0.897 0.102
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.900 0.100
E66.1 Drug-induced obesity
0.000 0.900 0.100
E28.2 Polycystic ovarian syndrome
0.000 0.900 0.099
E21.3 Hyperparathyroidism, unspecified
0.000 0.901 0.099
J33.1 Polypoid sinus degeneration
0.000 0.902 0.098
K90-K93 Other diseases of the digestive system
0.000 0.903 0.097
E66.0 Obesity due to excess calories
0.000 0.906 0.094
E23.6 Other disorders of pituitary gland
0.001 0.908 0.092
E23.7 Disorder of pituitary gland, unspecified
0.001 0.909 0.091
E24.0 Pituitary-dependent Cushing's disease
0.001 0.917 0.083
E66.8 Other obesity
0.000 0.921 0.079
E24.9 Cushing's syndrome, unspecified
0.001 0.926 0.074
J30-J39 Other diseases of upper respiratory tract
0.000 0.929 0.071
E23.0 Hypopituitarism
0.001 0.929 0.070
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.930 0.069
J47 Bronchiectasis
0.000 0.934 0.066
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.934 0.066
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.935 0.065
L43.9 Lichen planus, unspecified
0.063 0.937 0.001
J31.0 Chronic rhinitis
0.000 0.938 0.062
J36 Peritonsillar abscess
0.000 0.942 0.057
K91.4 Colostomy and enterostomy malfunction
0.000 0.943 0.057
J30 Vasomotor and allergic rhinitis
0.000 0.945 0.055
J40-J47 Chronic lower respiratory diseases
0.000 0.946 0.054
J45 Asthma
0.000 0.946 0.054
J45.9 Asthma, unspecified
0.000 0.947 0.053
J37 Chronic laryngitis and laryngotracheitis
0.000 0.949 0.050
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.950 0.050
K93.1 Megacolon in Chagas' disease
0.000 0.950 0.050
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.950 0.050
J32 Chronic sinusitis
0.000 0.952 0.048
J31.2 Chronic pharyngitis
0.000 0.952 0.048
J31.1 Chronic nasopharyngitis
0.000 0.953 0.047
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.953 0.047
K91.5 Postcholecystectomy syndrome
0.000 0.953 0.047
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.953 0.047
K91.1 Postgastric surgery syndromes
0.000 0.953 0.047
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.953 0.046
Chapter X Diseases of the respiratory system
0.000 0.954 0.046
J30.3 Other allergic rhinitis
0.000 0.956 0.044
E66.9 Obesity, unspecified
0.000 0.957 0.043
J42 Unspecified chronic bronchitis
0.000 0.958 0.042
J45.0 Predominantly allergic asthma
0.000 0.959 0.041
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.959 0.041
J30.1 Allergic rhinitis due to pollen
0.000 0.959 0.041
J30.2 Other seasonal allergic rhinitis
0.000 0.960 0.040
J30.0 Vasomotor rhinitis
0.000 0.960 0.040
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.961 0.039
J41 Simple and mucopurulent chronic bronchitis
0.000 0.961 0.039
J39 Other diseases of upper respiratory tract
0.000 0.961 0.039
J45.8 Mixed asthma
0.000 0.961 0.038
J45.1 Nonallergic asthma
0.000 0.961 0.038
J32.0 Chronic maxillary sinusitis
0.000 0.962 0.038
J34 Other disorders of nose and nasal sinuses
0.000 0.962 0.038
J30.4 Allergic rhinitis, unspecified
0.000 0.963 0.037
J32.2 Chronic ethmoidal sinusitis
0.000 0.963 0.037
J37.1 Chronic laryngotracheitis
0.000 0.964 0.036
J37.0 Chronic laryngitis
0.000 0.964 0.035
J32.3 Chronic sphenoidal sinusitis
0.000 0.965 0.035
J32.1 Chronic frontal sinusitis
0.000 0.965 0.035
J34.2 Deviated nasal septum
0.000 0.965 0.035
J32.4 Chronic pansinusitis
0.000 0.966 0.034
J38.2 Nodules of vocal cords
0.000 0.966 0.034
J32.8 Other chronic sinusitis
0.000 0.967 0.033
J00-J06 Acute upper respiratory infections
0.000 0.967 0.033
J43 Emphysema
0.000 0.967 0.033
J46 Status asthmaticus
0.000 0.968 0.032
J60-J70 Lung diseases due to external agents
0.000 0.968 0.032
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.969 0.031
J38.1 Polyp of vocal cord and larynx
0.000 0.969 0.031
J95-J99 Other diseases of the respiratory system
0.000 0.970 0.029
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.971 0.029
J38.6 Stenosis of larynx
0.000 0.972 0.028
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.972 0.028
J41.1 Mucopurulent chronic bronchitis
0.000 0.972 0.028
J41.0 Simple chronic bronchitis
0.000 0.972 0.028
M05-M14 Inflammatory polyarthropathies
0.028 0.972 0.000
J39.9 Disease of upper respiratory tract, unspecified
0.000 0.972 0.028
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified
0.000 0.972 0.028
J39.1 Other abscess of pharynx
0.000 0.972 0.028
J39.0 Retropharyngeal and parapharyngeal abscess
0.000 0.972 0.028
J35 Chronic diseases of tonsils and adenoids
0.000 0.972 0.027
J34.0 Abscess, furuncle and carbuncle of nose
0.000 0.972 0.028
K91.3 Postoperative intestinal obstruction
0.000 0.973 0.027
J03 Acute tonsillitis
0.000 0.973 0.027
E11 Non-insulin-dependent diabetes mellitus
0.000 0.973 0.027
J32.9 Chronic sinusitis, unspecified
0.000 0.973 0.027
J38.5 Laryngeal spasm
0.000 0.974 0.026
E70-E90 Metabolic disorders
0.000 0.974 0.026
J34.1 Cyst and mucocele of nose and nasal sinus
0.000 0.974 0.026
J39.2 Other diseases of pharynx
0.000 0.974 0.025
J38.4 Oedema of larynx
0.000 0.975 0.025
J38.0 Paralysis of vocal cords and larynx
0.000 0.975 0.025
J01 Acute sinusitis
0.000 0.975 0.025
J43.2 Centrilobular emphysema
0.000 0.975 0.024
J69 Pneumonitis due to solids and liquids
0.000 0.976 0.024
J04 Acute laryngitis and tracheitis
0.000 0.976 0.024
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.976 0.024
J38.3 Other diseases of vocal cords
0.000 0.976 0.024
K92 Other diseases of digestive system
0.000 0.976 0.024
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.976 0.024
J43.8 Other emphysema
0.000 0.976 0.023
J43.1 Panlobular emphysema
0.000 0.976 0.023
J43.0 MacLeod's syndrome
0.000 0.976 0.023
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.976 0.023
J03.9 Acute tonsillitis, unspecified
0.000 0.977 0.023
J00 Acute nasopharyngitis [common cold]
0.000 0.977 0.023

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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