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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2894181
log Bayes Factor = 114.59
Chromosome 6   position 31,174,527  (GRCh37) Explore rs2894181 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.000 1.000
R31 Unspecified haematuria
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.999 0.001 0.000
D86 Sarcoidosis
0.000 0.001 0.999
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.001 0.999
M06 Other rheumatoid arthritis
0.998 0.002 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.006 0.994
D70 Agranulocytosis
0.000 0.008 0.992
M06.3 Rheumatoid nodule
0.986 0.014 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.015 0.985
L40.0 Psoriasis vulgaris
0.000 0.017 0.983
M06.34 Rheumatoid nodule (Hand)
0.979 0.021 0.000
D69 Purpura and other haemorrhagic conditions
0.000 0.026 0.974
D72 Other disorders of white blood cells
0.000 0.029 0.971
D69.6 Thrombocytopenia, unspecified
0.000 0.030 0.970
D60-D64 Aplastic and other anaemias
0.000 0.033 0.967
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.964 0.036 0.000
D72.8 Other specified disorders of white blood cells
0.000 0.050 0.950
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.060 0.940
D64 Other anaemias
0.000 0.060 0.940
D61 Other aplastic anaemias
0.000 0.071 0.929
D50-D53 Nutritional anaemias
0.000 0.072 0.928
D86.3 Sarcoidosis of skin
0.000 0.083 0.917
D55-D59 Haemolytic anaemias
0.000 0.085 0.915
D80 Immunodeficiency with predominantly antibody defects
0.000 0.092 0.908
D66 Hereditary factor VIII deficiency
0.000 0.096 0.904
D51 Vitamin B12 deficiency anaemia
0.000 0.098 0.902
M05-M14 Inflammatory polyarthropathies
0.897 0.102 0.001
M05.9 Seropositive rheumatoid arthritis, unspecified
0.897 0.103 0.000
M05 Seropositive rheumatoid arthritis
0.897 0.103 0.000
D61.9 Aplastic anaemia, unspecified
0.000 0.108 0.892
D64.9 Anaemia, unspecified
0.000 0.118 0.882
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.129 0.871
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.871 0.129 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.867 0.133 0.000
M06.0 Seronegative rheumatoid arthritis
0.867 0.133 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.866 0.134 0.000
D59 Acquired haemolytic anaemia
0.000 0.138 0.862
L40.1 Generalised pustular psoriasis
0.000 0.141 0.859
D69.2 Other nonthrombocytopenic purpura
0.000 0.141 0.859
D86.0 Sarcoidosis of lung
0.000 0.141 0.858
D64.8 Other specified anaemias
0.000 0.146 0.854
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.853 0.147 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.845 0.155 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.844 0.156 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.166 0.834
M06.98 Rheumatoid arthritis, unspecified (Other)
0.818 0.182 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.817 0.183 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.810 0.190 0.000
D69.4 Other primary thrombocytopenia
0.000 0.192 0.808
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.213 0.787
L40.4 Guttate psoriasis
0.000 0.215 0.785
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.784 0.216 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.217 0.783
M06.1 Adult-onset Still's disease
0.783 0.217 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.218 0.782
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.220 0.780
D86.1 Sarcoidosis of lymph nodes
0.000 0.221 0.779
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.226 0.774
D59.1 Other autoimmune haemolytic anaemias
0.000 0.226 0.774
D83 Common variable immunodeficiency
0.000 0.228 0.772
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.772 0.228 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.228 0.772
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.231 0.769
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.234 0.766
M07.3 Other psoriatic arthropathies
0.005 0.237 0.759
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.242 0.757
L40.8 Other psoriasis
0.000 0.244 0.756
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.244 0.756
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.245 0.755
D58 Other hereditary haemolytic anaemias
0.000 0.251 0.749
D75 Other diseases of blood and blood-forming organs
0.000 0.251 0.749
D69.5 Secondary thrombocytopenia
0.000 0.266 0.734
M07.30 Other psoriatic arthropathies (Multiple sites)
0.001 0.266 0.733
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.277 0.723
M05.1 Rheumatoid lung disease
0.722 0.278 0.000
L40.2 Acrodermatitis continua
0.000 0.283 0.717
D81 Combined immunodeficiencies
0.000 0.283 0.717
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.716 0.283 0.000
D74 Methaemoglobinaemia
0.000 0.284 0.716
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.284 0.716
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.284 0.716
D61.0 Constitutional aplastic anaemia
0.000 0.285 0.715
M06.2 Rheumatoid bursitis
0.715 0.285 0.000
D84 Other immunodeficiencies
0.000 0.285 0.715
M06.33 Rheumatoid nodule (Forearm)
0.714 0.285 0.000
D72.1 Eosinophilia
0.000 0.288 0.712
M06.36 Rheumatoid nodule (Lower leg)
0.707 0.293 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.707 0.293 0.000
M06.38 Rheumatoid nodule (Other)
0.707 0.293 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.707 0.293 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.707 0.293 0.000
M06.4 Inflammatory polyarthropathy
0.705 0.295 0.000
D69.8 Other specified haemorrhagic conditions
0.000 0.301 0.698
M06.32 Rheumatoid nodule (Upper arm)
0.698 0.302 0.000
D72.9 Disorder of white blood cells, unspecified
0.000 0.304 0.696
D72.0 Genetic anomalies of leukocytes
0.000 0.304 0.696
M07 Psoriatic and enteropathic arthropathies
0.377 0.305 0.317
D69.1 Qualitative platelet defects
0.000 0.308 0.691
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.311 0.689
M06.30 Rheumatoid nodule (Multiple sites)
0.688 0.312 0.000
M06.8 Other specified rheumatoid arthritis
0.685 0.314 0.000
D61.1 Drug-induced aplastic anaemia
0.000 0.316 0.684
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.682 0.317 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.682 0.318 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.677 0.323 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.675 0.325 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.674 0.326 0.000
D89.3 Immune reconstitution syndrome
0.000 0.326 0.674
D64.4 Congenital dyserythropoietic anaemia
0.000 0.326 0.674
D64.3 Other sideroblastic anaemias
0.000 0.326 0.674
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.326 0.674
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.326 0.674
M07.34 Other psoriatic arthropathies (Hand)
0.002 0.330 0.667
K90 Intestinal malabsorption
0.000 0.331 0.669
D61.8 Other specified aplastic anaemias
0.000 0.334 0.666
D61.3 Idiopathic aplastic anaemia
0.000 0.334 0.666
D61.2 Aplastic anaemia due to other external agents
0.000 0.334 0.666
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.663 0.337 0.000
D55 Anaemia due to enzyme disorders
0.000 0.344 0.656
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.652 0.348 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.652 0.348 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.349 0.651
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.349 0.651
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.349 0.651
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.349 0.651
D57 Sickle-cell disorders
0.000 0.349 0.651
D67 Hereditary factor IX deficiency
0.000 0.350 0.650
M08 Juvenile arthritis
0.649 0.350 0.001
D64.0 Hereditary sideroblastic anaemia
0.000 0.350 0.649
D75.0 Familial erythrocytosis
0.000 0.351 0.649
D89.1 Cryoglobulinaemia
0.000 0.351 0.649
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.353 0.647
D51.2 Transcobalamin II deficiency
0.000 0.353 0.647
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.353 0.647
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.355 0.645
M12 Other specific arthropathies
0.644 0.356 0.001
M09 Juvenile arthritis in diseases classified elsewhere
0.643 0.356 0.001
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.643 0.357 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.643 0.357 0.000
M05.0 Felty's syndrome
0.643 0.357 0.000
M14 Arthropathies in other diseases classified elsewhere
0.637 0.362 0.001
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.366 0.634
D50 Iron deficiency anaemia
0.000 0.366 0.634
M06.10 Adult-onset Still's disease (Multiple sites)
0.629 0.371 0.000
M05.8 Other seropositive rheumatoid arthritis
0.629 0.371 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.371 0.628
D58.0 Hereditary spherocytosis
0.000 0.374 0.626
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.623 0.377 0.000
D86.8 Sarcoidosis of other and combined sites
0.000 0.378 0.622
M06.08 Seronegative rheumatoid arthritis (Other)
0.622 0.378 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.622 0.378 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.622 0.378 0.000
D82 Immunodeficiency associated with other major defects
0.000 0.381 0.618
D53 Other nutritional anaemias
0.000 0.382 0.618
D59.8 Other acquired haemolytic anaemias
0.000 0.382 0.618
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.382 0.618
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.382 0.618
D59.3 Haemolytic-uraemic syndrome
0.000 0.382 0.618
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.382 0.618
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.382 0.618
D76.3 Other histiocytosis syndromes
0.000 0.387 0.613
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.388 0.611
D83.9 Common variable immunodeficiency, unspecified
0.000 0.391 0.609
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.392 0.608
D50.9 Iron deficiency anaemia, unspecified
0.000 0.394 0.606
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.601 0.399 0.000
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.403 0.597
M05.19 Rheumatoid lung disease (Site unspecified)
0.597 0.403 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.003 0.407 0.591
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.410 0.590
D73 Diseases of spleen
0.000 0.418 0.582
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.003 0.419 0.579
K90.9 Intestinal malabsorption, unspecified
0.000 0.422 0.578
M05.2 Rheumatoid vasculitis
0.576 0.424 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.003 0.436 0.561
M06.19 Adult-onset Still's disease (Site unspecified)
0.561 0.439 0.000
M06.18 Adult-onset Still's disease (Other)
0.561 0.439 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.561 0.439 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.561 0.439 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.561 0.439 0.000
M06.14 Adult-onset Still's disease (Hand)
0.561 0.439 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.561 0.439 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.561 0.439 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.561 0.439 0.000
D84.1 Defects in the complement system
0.000 0.441 0.559
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.445 0.555
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.445 0.555
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.445 0.555
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.445 0.555
D83.8 Other common variable immunodeficiencies
0.000 0.446 0.554
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.446 0.554
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.446 0.554
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.446 0.554
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.449 0.550
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.547 0.452 0.000
M07.38 Other psoriatic arthropathies (Other)
0.003 0.453 0.544
M07.33 Other psoriatic arthropathies (Forearm)
0.003 0.453 0.544
M07.32 Other psoriatic arthropathies (Upper arm)
0.003 0.453 0.544
D69.9 Haemorrhagic condition, unspecified
0.000 0.454 0.546
M07.31 Other psoriatic arthropathies (Shoulder region)
0.003 0.457 0.540
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.463 0.537
D58.1 Hereditary elliptocytosis
0.000 0.463 0.537
D52 Folate deficiency anaemia
0.000 0.465 0.535
D84.9 Immunodeficiency, unspecified
0.000 0.468 0.532
D58.2 Other haemoglobinopathies
0.000 0.469 0.531
M05.18 Rheumatoid lung disease (Other)
0.518 0.482 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.518 0.482 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.518 0.482 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.518 0.482 0.000
M05.14 Rheumatoid lung disease (Hand)
0.518 0.482 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.518 0.482 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.518 0.482 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.518 0.482 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.518 0.482 0.000
D81.9 Combined immunodeficiency, unspecified
0.000 0.486 0.514
D81.8 Other combined immunodeficiencies
0.000 0.486 0.514
D81.7 Major histocompatibility complex class II deficiency
0.000 0.486 0.514
D81.6 Major histocompatibility complex class I deficiency
0.000 0.486 0.514
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.486 0.514
D81.4 Nezelof's syndrome
0.000 0.486 0.514
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.486 0.514
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.486 0.514
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.486 0.514
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.486 0.514
D74.9 Methaemoglobinaemia, unspecified
0.000 0.486 0.513
D74.8 Other methaemoglobinaemias
0.000 0.486 0.513
D74.0 Congenital methaemoglobinaemia
0.000 0.486 0.513
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.513 0.487 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.513 0.487 0.000
M06.28 Rheumatoid bursitis (Other)
0.513 0.487 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.513 0.487 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.513 0.487 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.513 0.487 0.000
M06.24 Rheumatoid bursitis (Hand)
0.513 0.487 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.513 0.487 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.513 0.487 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.513 0.487 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.513 0.487 0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.487 0.512
M06.46 Inflammatory polyarthropathy (Lower leg)
0.512 0.488 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.506 0.494 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.506 0.494 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.506 0.494 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.506 0.494 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.506 0.494 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.506 0.494 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.506 0.494 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.502 0.498 0.000
M07.6 Other enteropathic arthropathies
0.271 0.502 0.228
M07.5 Arthropathy in ulcerative colitis
0.271 0.502 0.228
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.271 0.502 0.228
M07.2 Psoriatic spondylitis
0.271 0.502 0.228
M07.1 Arthritis mutilans
0.271 0.502 0.228
M07.0 Distal interphalangeal psoriatic arthropathy
0.271 0.502 0.228
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.497 0.503 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.491 0.508 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.491 0.508 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.491 0.508 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.491 0.508 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.491 0.508 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.491 0.508 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.491 0.508 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.491 0.508 0.000
M14.6 Neuropathic arthropathy
0.482 0.517 0.000
M12.5 Traumatic arthropathy
0.481 0.519 0.001
K90.3 Pancreatic steatorrhoea
0.000 0.520 0.480
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.520 0.480
K90.1 Tropical sprue
0.000 0.520 0.480
M14.8 Arthropathies in other specified diseases classified elsewhere
0.479 0.520 0.000
M12.2 Villonodular synovitis (pigmented)
0.479 0.521 0.001
M11 Other crystal arthropathies
0.475 0.524 0.001
D50.1 Sideropenic dysphagia
0.000 0.529 0.471
M08.0 Juvenile rheumatoid arthritis
0.470 0.529 0.001
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.529 0.470
D55.8 Other anaemias due to enzyme disorders
0.000 0.529 0.470
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.529 0.470
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.529 0.470
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.529 0.470
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.529 0.470
M08.2 Juvenile arthritis with systemic onset
0.467 0.532 0.001
D57.8 Other sickle-cell disorders
0.000 0.533 0.467
D57.3 Sickle-cell trait
0.000 0.533 0.467
D57.2 Double heterozygous sickling disorders
0.000 0.533 0.467
D57.0 Sickle-cell anaemia with crisis
0.000 0.533 0.467
M08.9 Juvenile arthritis, unspecified
0.466 0.534 0.001
M08.8 Other juvenile arthritis
0.466 0.534 0.001
M08.4 Pauciarticular juvenile arthritis
0.466 0.534 0.001
M08.3 Juvenile polyarthritis (seronegative)
0.466 0.534 0.001
M08.1 Juvenile ankylosing spondylitis
0.466 0.534 0.001
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.464 0.536 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.461 0.538 0.001
M09.2 Juvenile arthritis in ulcerative colitis
0.461 0.538 0.001
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.461 0.538 0.001
M09.0 Juvenile arthritis in psoriasis
0.461 0.538 0.001
M12.4 Intermittent hydrarthrosis
0.461 0.538 0.001
M12.1 Kaschin-Beck disease
0.461 0.538 0.001
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.461 0.538 0.001
D57.1 Sickle-cell anaemia without crisis
0.000 0.538 0.462
M05.09 Felty's syndrome (Site unspecified)
0.461 0.539 0.000
M05.08 Felty's syndrome (Other)
0.461 0.539 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.461 0.539 0.000
M05.06 Felty's syndrome (Lower leg)
0.461 0.539 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.461 0.539 0.000
M05.04 Felty's syndrome (Hand)
0.461 0.539 0.000
M05.03 Felty's syndrome (Forearm)
0.461 0.539 0.000
M05.02 Felty's syndrome (Upper arm)
0.461 0.539 0.000
M05.01 Felty's syndrome (Shoulder region)
0.461 0.539 0.000
M05.00 Felty's syndrome (Multiple sites)
0.461 0.539 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.461 0.539 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.461 0.539 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.461 0.539 0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.461 0.539 0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.461 0.539 0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.461 0.539 0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.461 0.539 0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.461 0.539 0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.461 0.539 0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.461 0.539 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.457 0.543 0.001
M14.4 Arthropathy in amyloidosis
0.457 0.543 0.001
M14.3 Lipoid dermatoarthritis
0.457 0.543 0.001
M14.1 Crystal arthropathy in other metabolic disorders
0.457 0.543 0.001
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.457 0.543 0.001
D56 Thalassaemia
0.001 0.543 0.457
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.455 0.545 0.000
D60.8 Other acquired pure red cell aplasias
0.000 0.545 0.455
D60.1 Transient acquired pure red cell aplasia
0.000 0.545 0.455
D60.0 Chronic acquired pure red cell aplasia
0.000 0.545 0.455
D73.3 Abscess of spleen
0.000 0.546 0.454
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.451 0.549 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.451 0.549 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.451 0.549 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.451 0.549 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.451 0.549 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.451 0.549 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.451 0.549 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.451 0.549 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.451 0.549 0.000
M10 Gout
0.448 0.551 0.000
M12.3 Palindromic rheumatism
0.445 0.555 0.001
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.556 0.443
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.556 0.443
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.556 0.443
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.556 0.443
D82.2 Immunodeficiency with short-limbed stature
0.000 0.556 0.443
D82.0 Wiskott-Aldrich syndrome
0.000 0.556 0.443
D53.8 Other specified nutritional anaemias
0.000 0.556 0.443
D53.2 Scorbutic anaemia
0.000 0.556 0.443
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.556 0.443
D53.0 Protein deficiency anaemia
0.000 0.556 0.443
M12.8 Other specific arthropathies, not elsewhere classified
0.438 0.561 0.001
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.437 0.563 0.000
D73.1 Hypersplenism
0.000 0.568 0.432
D73.9 Disease of spleen, unspecified
0.000 0.568 0.431
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.431 0.569 0.000
D62 Acute posthaemorrhagic anaemia
0.000 0.570 0.430
K90.8 Other intestinal malabsorption
0.000 0.578 0.422
D84.8 Other specified immunodeficiencies
0.000 0.579 0.420
D73.4 Cyst of spleen
0.000 0.580 0.420
D73.2 Chronic congestive splenomegaly
0.000 0.582 0.417
D75.2 Essential thrombocytosis
0.000 0.583 0.417
M05.28 Rheumatoid vasculitis (Other)
0.413 0.587 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.413 0.587 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.413 0.587 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.413 0.587 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.413 0.587 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.413 0.587 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.413 0.587 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.413 0.587 0.000
D73.5 Infarction of spleen
0.000 0.592 0.408
D73.8 Other diseases of spleen
0.000 0.595 0.405
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.600 0.400
M05.20 Rheumatoid vasculitis (Multiple sites)
0.398 0.602 0.000
D53.9 Nutritional anaemia, unspecified
0.000 0.604 0.396
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.604 0.395
M14.2 Diabetic arthropathy
0.388 0.611 0.001
M12.24 Villonodular synovitis (pigmented) (Hand)
0.388 0.611 0.000
M13 Other arthritis
0.387 0.613 0.000
D52.8 Other folate deficiency anaemias
0.000 0.616 0.383
D52.1 Drug-induced folate deficiency anaemia
0.000 0.616 0.383
D52.0 Dietary folate deficiency anaemia
0.000 0.616 0.383
D69.0 Allergic purpura
0.001 0.625 0.374
C90.0 Multiple myeloma
0.000 0.629 0.371
M05.29 Rheumatoid vasculitis (Site unspecified)
0.365 0.634 0.001
M12.57 Traumatic arthropathy (Ankle and foot)
0.364 0.636 0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.194 0.643 0.163
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.194 0.643 0.163
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.194 0.643 0.163
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.194 0.643 0.163
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.194 0.643 0.163
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.194 0.643 0.163
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.194 0.643 0.163
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.194 0.643 0.163
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.194 0.643 0.163
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.194 0.643 0.163
M07.19 Arthritis mutilans (Site unspecified)
0.194 0.643 0.163
M07.18 Arthritis mutilans (Other)
0.194 0.643 0.163
M07.17 Arthritis mutilans (Ankle and foot)
0.194 0.643 0.163
M07.16 Arthritis mutilans (Lower leg)
0.194 0.643 0.163
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.194 0.643 0.163
M07.14 Arthritis mutilans (Hand)
0.194 0.643 0.163
M07.13 Arthritis mutilans (Forearm)
0.194 0.643 0.163
M07.12 Arthritis mutilans (Upper arm)
0.194 0.643 0.163
M07.11 Arthritis mutilans (Shoulder region)
0.194 0.643 0.163
M07.10 Arthritis mutilans (Multiple sites)
0.194 0.643 0.163
M07.29 Psoriatic spondylitis (Site unspecified)
0.194 0.643 0.163
M07.28 Psoriatic spondylitis (Other)
0.194 0.643 0.163
M07.27 Psoriatic spondylitis (Ankle and foot)
0.194 0.643 0.163
M07.26 Psoriatic spondylitis (Lower leg)
0.194 0.643 0.163
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.194 0.643 0.163
M07.24 Psoriatic spondylitis (Hand)
0.194 0.643 0.163
M07.23 Psoriatic spondylitis (Forearm)
0.194 0.643 0.163
M07.22 Psoriatic spondylitis (Upper arm)
0.194 0.643 0.163
M07.21 Psoriatic spondylitis (Shoulder region)
0.194 0.643 0.163
M07.20 Psoriatic spondylitis (Multiple sites)
0.194 0.643 0.163
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.194 0.643 0.163
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.194 0.643 0.163
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.194 0.643 0.163
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.194 0.643 0.163
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.194 0.643 0.163
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.194 0.643 0.163
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.194 0.643 0.163
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.194 0.643 0.163
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.194 0.643 0.163
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.194 0.643 0.163
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.194 0.643 0.163
M07.58 Arthropathy in ulcerative colitis (Other)
0.194 0.643 0.163
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.194 0.643 0.163
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.194 0.643 0.163
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.194 0.643 0.163
M07.54 Arthropathy in ulcerative colitis (Hand)
0.194 0.643 0.163
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.194 0.643 0.163
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.194 0.643 0.163
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.194 0.643 0.163
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.194 0.643 0.163
M07.69 Other enteropathic arthropathies (Site unspecified)
0.194 0.643 0.163
M07.68 Other enteropathic arthropathies (Other)
0.194 0.643 0.163
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.194 0.643 0.163
M07.66 Other enteropathic arthropathies (Lower leg)
0.194 0.643 0.163
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.194 0.643 0.163
M07.64 Other enteropathic arthropathies (Hand)
0.194 0.643 0.163
M07.63 Other enteropathic arthropathies (Forearm)
0.194 0.643 0.163
M07.62 Other enteropathic arthropathies (Upper arm)
0.194 0.643 0.163
M07.61 Other enteropathic arthropathies (Shoulder region)
0.194 0.643 0.163
M07.60 Other enteropathic arthropathies (Multiple sites)
0.194 0.643 0.163
M08.00 Juvenile rheumatoid arthritis (Multiple sites)
0.353 0.646 0.000
D82.1 Di George's syndrome
0.001 0.655 0.345
M12.59 Traumatic arthropathy (Site unspecified)
0.345 0.655 0.001
M12.58 Traumatic arthropathy (Other)
0.345 0.655 0.001
M12.56 Traumatic arthropathy (Lower leg)
0.345 0.655 0.001
M12.55 Traumatic arthropathy (Pelvic region and thigh)
0.345 0.655 0.001
M12.54 Traumatic arthropathy (Hand)
0.345 0.655 0.001
M12.53 Traumatic arthropathy (Forearm)
0.345 0.655 0.001
M12.52 Traumatic arthropathy (Upper arm)
0.345 0.655 0.001
M12.51 Traumatic arthropathy (Shoulder region)
0.345 0.655 0.001
M12.50 Traumatic arthropathy (Multiple sites)
0.345 0.655 0.001
D75.1 Secondary polycythaemia
0.000 0.655 0.345
M10.3 Gout due to impairment of renal function
0.344 0.656 0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)
0.343 0.656 0.001
M12.28 Villonodular synovitis (pigmented) (Other)
0.343 0.656 0.001
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)
0.343 0.656 0.001
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)
0.343 0.656 0.001
M12.23 Villonodular synovitis (pigmented) (Forearm)
0.343 0.656 0.001
M12.22 Villonodular synovitis (pigmented) (Upper arm)
0.343 0.656 0.001
M12.21 Villonodular synovitis (pigmented) (Shoulder region)
0.343 0.656 0.001
M12.20 Villonodular synovitis (pigmented) (Multiple sites)
0.343 0.656 0.001
M11.9 Crystal arthropathy, unspecified
0.343 0.656 0.001
M11.1 Familial chondrocalcinosis
0.341 0.658 0.001
M11.0 Hydroxyapatite deposition disease
0.341 0.658 0.001
M08.08 Juvenile rheumatoid arthritis (Other)
0.337 0.662 0.001
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)
0.337 0.662 0.001
M08.06 Juvenile rheumatoid arthritis (Lower leg)
0.337 0.662 0.001
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)
0.337 0.662 0.001
M08.04 Juvenile rheumatoid arthritis (Hand)
0.337 0.662 0.001
M08.03 Juvenile rheumatoid arthritis (Forearm)
0.337 0.662 0.001
M08.02 Juvenile rheumatoid arthritis (Upper arm)
0.337 0.662 0.001
M08.01 Juvenile rheumatoid arthritis (Shoulder region)
0.337 0.662 0.001
M08.29 Juvenile arthritis with systemic onset (Site unspecified)
0.337 0.663 0.001
M08.28 Juvenile arthritis with systemic onset (Other)
0.335 0.664 0.001
M08.27 Juvenile arthritis with systemic onset (Ankle and foot)
0.335 0.664 0.001
M08.26 Juvenile arthritis with systemic onset (Lower leg)
0.335 0.664 0.001
M08.25 Juvenile arthritis with systemic onset (Pelvic region and thigh)
0.335 0.664 0.001
M08.24 Juvenile arthritis with systemic onset (Hand)
0.335 0.664 0.001
M08.23 Juvenile arthritis with systemic onset (Forearm)
0.335 0.664 0.001
M08.22 Juvenile arthritis with systemic onset (Upper arm)
0.335 0.664 0.001
M08.21 Juvenile arthritis with systemic onset (Shoulder region)
0.335 0.664 0.001
M08.20 Juvenile arthritis with systemic onset (Multiple sites)
0.335 0.664 0.001
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.665 0.335
M08.19 Juvenile ankylosing spondylitis (Site unspecified)
0.334 0.665 0.001
M08.18 Juvenile ankylosing spondylitis (Other)
0.334 0.665 0.001
M08.17 Juvenile ankylosing spondylitis (Ankle and foot)
0.334 0.665 0.001
M08.16 Juvenile ankylosing spondylitis (Lower leg)
0.334 0.665 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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