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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2905722
log Bayes Factor = 89.046
Chromosome 6   position 31,449,327  (GRCh37) Explore rs2905722 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
0.000 0.001 0.999
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.001 0.999
I20 Angina pectoris
0.000 0.001 0.999
I10-I15 Hypertensive diseases
0.000 0.001 0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.002 0.998
I20.9 Angina pectoris, unspecified
0.000 0.002 0.998
E70-E90 Metabolic disorders
0.000 0.004 0.996
I22 Subsequent myocardial infarction
0.000 0.005 0.995
E10.1 With ketoacidosis
0.000 0.006 0.994
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.007 0.993
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.008 0.992
L40-L45 Papulosquamous disorders
0.000 0.009 0.991
I25.2 Old myocardial infarction
0.000 0.009 0.991
I25.5 Ischaemic cardiomyopathy
0.000 0.010 0.990
M06 Other rheumatoid arthritis
0.000 0.012 0.988
Chapter IX Diseases of the circulatory system
0.000 0.012 0.988
G35-G37 Demyelinating diseases of the central nervous system
0.985 0.015 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.015 0.985
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.017 0.983
E14.3 With ophthalmic complications
0.000 0.017 0.983
M05-M14 Inflammatory polyarthropathies
0.000 0.018 0.982
M70-M79 Other soft tissue disorders
0.000 0.018 0.982
M45 Ankylosing spondylitis
0.000 0.018 0.982
G37 Other demyelinating diseases of central nervous system
0.982 0.018 0.000
M75 Shoulder lesions
0.000 0.020 0.980
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.020 0.980
M75.0 Adhesive capsulitis of shoulder
0.000 0.022 0.978
J45.9 Asthma, unspecified
0.000 0.023 0.977
M45-M49 Spondylopathies
0.000 0.024 0.976
I20.0 Unstable angina
0.000 0.024 0.976
G37.9 Demyelinating disease of central nervous system, unspecified
0.974 0.026 0.000
E10.4 With neurological complications
0.000 0.028 0.972
L43 Lichen planus
0.000 0.030 0.970
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.038 0.962
M75.4 Impingement syndrome of shoulder
0.000 0.038 0.962
I24 Other acute ischaemic heart diseases
0.000 0.039 0.961
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.040 0.960
I21 Acute myocardial infarction
0.000 0.046 0.954
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.051 0.949
L43.9 Lichen planus, unspecified
0.000 0.057 0.943
M79.6 Pain in limb
0.000 0.058 0.942
# Top node
0.000 0.058 0.942
I12 Hypertensive renal disease
0.000 0.065 0.935
E16 Other disorders of pancreatic internal secretion
0.000 0.065 0.935
E78.2 Mixed hyperlipidaemia
0.000 0.068 0.932
M79.65 Pain in limb (Pelvic region and thigh)
0.000 0.072 0.928
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.076 0.924
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.080 0.920
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.085 0.915
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.087 0.913
E78.8 Other disorders of lipoprotein metabolism
0.000 0.093 0.907
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.095 0.905
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.101 0.899
E13 Other specified diabetes mellitus
0.000 0.102 0.898
E05.9 Thyrotoxicosis, unspecified
0.000 0.105 0.895
E16.2 Hypoglycaemia, unspecified
0.000 0.106 0.894
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.111 0.889
E10.2 With renal complications
0.000 0.115 0.885
G37.8 Other specified demyelinating diseases of central nervous system
0.883 0.117 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.117 0.883
R07.4 Chest pain, unspecified
0.000 0.117 0.883
I15 Secondary hypertension
0.000 0.119 0.881
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.120 0.880
I21.4 Acute subendocardial myocardial infarction
0.000 0.129 0.871
E11.2 With renal complications
0.000 0.132 0.868
I12.9 Hypertensive renal disease without renal failure
0.000 0.136 0.864
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.136 0.864
M05 Seropositive rheumatoid arthritis
0.000 0.140 0.860
E11.0 With coma
0.000 0.143 0.857
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.147 0.853
M79.62 Pain in limb (Upper arm)
0.000 0.147 0.853
I21.9 Acute myocardial infarction, unspecified
0.000 0.147 0.853
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.153 0.847
E10.8 With unspecified complications
0.000 0.160 0.840
M06.3 Rheumatoid nodule
0.000 0.169 0.831
E07 Other disorders of thyroid
0.000 0.172 0.828
E13.9 Without complications
0.000 0.175 0.825
L40.8 Other psoriasis
0.000 0.177 0.823
M70.4 Prepatellar bursitis
0.000 0.181 0.819
I24.8 Other forms of acute ischaemic heart disease
0.000 0.182 0.818
E74 Other disorders of carbohydrate metabolism
0.000 0.183 0.817
L43.8 Other lichen planus
0.000 0.186 0.814
M75.2 Bicipital tendinitis
0.000 0.186 0.814
E11.1 With ketoacidosis
0.000 0.187 0.813
M79.7 Fibromyalgia
0.000 0.190 0.810
M79.64 Pain in limb (Hand)
0.000 0.193 0.807
E10.5 With peripheral circulatory complications
0.000 0.203 0.797
I25.3 Aneurysm of heart
0.000 0.204 0.796
E10.6 With other specified complications
0.000 0.204 0.796
E10.0 With coma
0.000 0.204 0.796
E78.5 Hyperlipidaemia, unspecified
0.000 0.207 0.793
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.207 0.793
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.207 0.792
M79.1 Myalgia
0.000 0.211 0.789
M07 Psoriatic and enteropathic arthropathies
0.000 0.213 0.787
I15.1 Hypertension secondary to other renal disorders
0.000 0.214 0.786
I23 Certain current complications following acute myocardial infarction
0.000 0.222 0.778
E78.1 Pure hyperglyceridaemia
0.000 0.230 0.770
K90 Intestinal malabsorption
0.000 0.231 0.769
E16.1 Other hypoglycaemia
0.000 0.233 0.767
I12.0 Hypertensive renal disease with renal failure
0.000 0.233 0.767
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.238 0.762
E85 Amyloidosis
0.000 0.246 0.754
M70.6 Trochanteric bursitis
0.000 0.249 0.750
E40-E46 Malnutrition
0.000 0.250 0.750
E11.4 With neurological complications
0.000 0.251 0.749
M11 Other crystal arthropathies
0.000 0.252 0.748
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.257 0.743
I11 Hypertensive heart disease
0.000 0.257 0.743
M79.60 Pain in limb (Multiple sites)
0.000 0.259 0.741
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.259 0.741
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.261 0.739
M79.79 Fibromyalgia (Site unspecified)
0.000 0.262 0.738
M79.67 Pain in limb (Ankle and foot)
0.000 0.263 0.737
L40.0 Psoriasis vulgaris
0.000 0.263 0.737
M79.63 Pain in limb (Forearm)
0.000 0.263 0.737
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.265 0.735
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.268 0.732
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.279 0.721
M49 Spondylopathies in diseases classified elsewhere
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
I20.1 Angina pectoris with documented spasm
0.000 0.284 0.716
I13 Hypertensive heart and renal disease
0.000 0.284 0.716
M79.69 Pain in limb (Site unspecified)
0.000 0.284 0.716
E79 Disorders of purine and pyrimidine metabolism
0.000 0.286 0.714
E77 Disorders of glycoprotein metabolism
0.000 0.286 0.714
E76 Disorders of glycosaminoglycan metabolism
0.000 0.286 0.714
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.286 0.714
E72 Other disorders of amino-acid metabolism
0.000 0.286 0.714
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.286 0.714
E70 Disorders of aromatic amino-acid metabolism
0.000 0.286 0.714
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.286 0.714
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.711 0.289 0.000
L44 Other papulosquamous disorders
0.000 0.289 0.711
L41 Parapsoriasis
0.000 0.289 0.711
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.289 0.711
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.290 0.710
M06.8 Other specified rheumatoid arthritis
0.000 0.291 0.709
M06.2 Rheumatoid bursitis
0.000 0.291 0.709
M06.1 Adult-onset Still's disease
0.000 0.291 0.709
E07.9 Disorder of thyroid, unspecified
0.000 0.291 0.709
I00-I02 Acute rheumatic fever
0.000 0.292 0.708
E14.6 With other specified complications
0.000 0.292 0.708
G36 Other acute disseminated demyelination
0.706 0.294 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.296 0.704
M08 Juvenile arthritis
0.000 0.296 0.704
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.296 0.704
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.296 0.704
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.296 0.704
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.296 0.704
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.296 0.704
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.296 0.704
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.296 0.704
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.296 0.704
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.296 0.704
G37.5 Concentric sclerosis [Balo]
0.704 0.296 0.000
G37.4 Subacute necrotising myelitis
0.704 0.296 0.000
G37.2 Central pontine myelinolysis
0.704 0.296 0.000
G37.1 Central demyelination of corpus callosum
0.704 0.296 0.000
G37.0 Diffuse sclerosis
0.704 0.296 0.000
M75.8 Other shoulder lesions
0.000 0.297 0.703
M70.5 Other bursitis of knee
0.000 0.298 0.702
M79.9 Soft tissue disorder, unspecified
0.000 0.298 0.702
L42 Pityriasis rosea
0.000 0.303 0.696
M06.34 Rheumatoid nodule (Hand)
0.000 0.304 0.696
L43.3 Subacute (active) lichen planus
0.000 0.305 0.695
L43.2 Lichenoid drug reaction
0.000 0.305 0.695
L43.1 Bullous lichen planus
0.000 0.305 0.695
L43.0 Hypertrophic lichen planus
0.000 0.305 0.695
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.305 0.695
I22.8 Subsequent myocardial infarction of other sites
0.000 0.305 0.694
M06.4 Inflammatory polyarthropathy
0.000 0.309 0.691
E15 Nondiabetic hypoglycaemic coma
0.000 0.310 0.690
E11.6 With other specified complications
0.000 0.311 0.689
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.311 0.689
M79.18 Myalgia (Other)
0.000 0.312 0.688
E06 Thyroiditis
0.000 0.313 0.687
M91-M94 Chondropathies
0.000 0.314 0.686
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.316 0.684
E11.5 With peripheral circulatory complications
0.000 0.317 0.683
M14 Arthropathies in other diseases classified elsewhere
0.000 0.319 0.681
M79.3 Panniculitis, unspecified
0.000 0.320 0.680
M79.2 Neuralgia and neuritis, unspecified
0.000 0.321 0.679
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.325 0.675
M71 Other bursopathies
0.000 0.325 0.674
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.327 0.673
E83 Disorders of mineral metabolism
0.538 0.328 0.134
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.329 0.670
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.329 0.670
E16.4 Abnormal secretion of gastrin
0.000 0.329 0.670
E16.3 Increased secretion of glucagon
0.000 0.329 0.670
E84 Cystic fibrosis
0.000 0.331 0.669
E05.5 Thyroid crisis or storm
0.000 0.338 0.662
E05.4 Thyrotoxicosis factitia
0.000 0.338 0.662
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.338 0.662
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.338 0.662
I15.9 Seconday hypertension, unspecified
0.000 0.341 0.659
E78.4 Other hyperlipidaemia
0.000 0.346 0.654
M07.3 Other psoriatic arthropathies
0.000 0.352 0.648
M75.3 Calcific tendinitis of shoulder
0.000 0.352 0.648
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.000 0.355 0.645
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.000 0.355 0.645
M70.3 Other bursitis of elbow
0.000 0.355 0.645
M70.1 Bursitis of hand
0.000 0.355 0.645
M70.0 Chronic crepitant synovitis of hand and wrist
0.000 0.355 0.645
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.000 0.356 0.644
E13.8 With unspecified complications
0.000 0.356 0.644
E13.7 With multiple complications
0.000 0.356 0.644
E13.6 With other specified complications
0.000 0.356 0.644
E13.5 With peripheral circulatory complications
0.000 0.356 0.644
E13.4 With neurological complications
0.000 0.356 0.644
E13.3 With ophthalmic complications
0.000 0.356 0.644
E13.2 With renal complications
0.000 0.356 0.644
E13.1 With ketoacidosis
0.000 0.356 0.644
E13.0 With coma
0.000 0.356 0.644
E11.3 With ophthalmic complications
0.000 0.359 0.641
I24.1 Dressler's syndrome
0.000 0.361 0.639
H30-H36 Disorders of choroid and retina
0.000 0.363 0.637
Chapter VII Diseases of the eye and adnexa
0.000 0.364 0.636
M76 Enthesopathies of lower limb, excluding foot
0.000 0.366 0.634
M79.4 Hypertrophy of (infrapatellar) fat pad
0.000 0.366 0.634
H36 Retinal disorders in diseases classified elsewhere
0.000 0.367 0.633
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.367 0.633
H36.0 Diabetic retinopathy
0.000 0.368 0.632
I15.8 Other secondary hypertension
0.000 0.368 0.632
I15.2 Hypertension secondary to endocrine disorders
0.000 0.368 0.632
I15.0 Renovascular hypertension
0.000 0.368 0.632
E05.8 Other thyrotoxicosis
0.000 0.379 0.621
I23.8 Other current complications following acute myocardial infarction
0.000 0.381 0.619
E85.9 Amyloidosis, unspecified
0.000 0.382 0.618
K90-K93 Other diseases of the digestive system
0.000 0.383 0.617
M05.8 Other seropositive rheumatoid arthritis
0.000 0.383 0.617
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.383 0.617
M05.1 Rheumatoid lung disease
0.000 0.383 0.617
M05.0 Felty's syndrome
0.000 0.383 0.617
E11.8 With unspecified complications
0.000 0.390 0.610
M11.2 Other chondrocalcinosis
0.000 0.392 0.608
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.393 0.607
I25.4 Coronary artery aneurysm
0.000 0.394 0.606
E03.8 Other specified hypothyroidism
0.000 0.394 0.606
E89.3 Postprocedural hypopituitarism
0.000 0.395 0.605
Chapter XI Diseases of the digestive system
0.000 0.397 0.603
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.397 0.603
M12 Other specific arthropathies
0.000 0.399 0.600
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.401 0.599
H35 Other retinal disorders
0.000 0.401 0.599
M79.68 Pain in limb (Other)
0.000 0.402 0.598
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.404 0.595
M06.38 Rheumatoid nodule (Other)
0.000 0.404 0.595
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.404 0.595
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.404 0.595
M06.33 Rheumatoid nodule (Forearm)
0.000 0.404 0.595
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.404 0.595
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.404 0.595
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.404 0.595
E07.1 Dyshormogenetic goitre
0.000 0.406 0.594
E07.0 Hypersecretion of calcitonin
0.000 0.406 0.594
E88 Other metabolic disorders
0.000 0.408 0.591
M79.15 Myalgia (Pelvic region and thigh)
0.000 0.411 0.588
M70.49 Prepatellar bursitis-Site unspec
0.000 0.412 0.587
M70.48 Prepatellar bursitis-Other
0.000 0.412 0.587
M70.47 Prepatellar bursitis-Ankle/Foot
0.000 0.412 0.587
M70.45 Prepatellar bursitis-Pelvic/Thigh
0.000 0.412 0.587
M70.44 Prepatellar bursitis-Hand
0.000 0.412 0.587
M70.43 Prepatellar bursitis-Forearm
0.000 0.412 0.587
M70.42 Prepatellar bursitis-Upper arm
0.000 0.412 0.587
M70.41 Prepatellar bursitis-Shldr region
0.000 0.412 0.587
M70.40 Prepatellar bursitis-Mult sites
0.000 0.412 0.587
E07.8 Other specified disorders of thyroid
0.000 0.413 0.587
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.414 0.586
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.414 0.586
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.414 0.586
E74.2 Disorders of galactose metabolism
0.000 0.414 0.586
E74.1 Disorders of fructose metabolism
0.000 0.414 0.586
E74.0 Glycogen storage disease
0.000 0.414 0.586
M79.78 Fibromyalgia (Other)
0.000 0.419 0.581
M79.77 Fibromyalgia (Ankle and foot)
0.000 0.419 0.581
M79.76 Fibromyalgia (Lower leg)
0.000 0.419 0.581
M79.75 Fibromyalgia (Pelvic region and thigh)
0.000 0.419 0.581
M79.74 Fibromyalgia (Hand)
0.000 0.419 0.581
M79.73 Fibromyalgia (Forearm)
0.000 0.419 0.581
M79.72 Fibromyalgia (Upper arm)
0.000 0.419 0.581
M79.71 Fibromyalgia (Shoulder region)
0.000 0.419 0.581
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.421 0.579
M79.19 Myalgia (Site unspecified)
0.000 0.422 0.578
M70.7 Other bursitis of hip
0.000 0.423 0.577
H35.8 Other specified retinal disorders
0.000 0.424 0.576
M79.61 Pain in limb (Shoulder region)
0.000 0.424 0.576
M79.16 Myalgia (Lower leg)
0.000 0.425 0.575
L10-L14 Bullous disorders
0.000 0.427 0.572
E46 Unspecified protein-energy malnutrition
0.000 0.429 0.571
M70.2 Olecranon bursitis
0.000 0.430 0.570
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.431 0.569
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.431 0.569
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.431 0.569
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.431 0.569
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.431 0.569
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.431 0.569
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.431 0.569
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.431 0.569
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.431 0.568
M79.17 Myalgia (Ankle and foot)
0.000 0.434 0.565
M79.14 Myalgia (Hand)
0.000 0.434 0.565
M79.13 Myalgia (Forearm)
0.000 0.434 0.565
M79.12 Myalgia (Upper arm)
0.000 0.434 0.565
M07.6 Other enteropathic arthropathies
0.000 0.435 0.564
M07.5 Arthropathy in ulcerative colitis
0.000 0.435 0.564
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.435 0.564
M07.2 Psoriatic spondylitis
0.000 0.435 0.564
M07.1 Arthritis mutilans
0.000 0.435 0.564
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.435 0.564
H25-H28 Disorders of lens
0.000 0.437 0.563
E73 Lactose intolerance
0.000 0.437 0.563
M79.11 Myalgia (Shoulder region)
0.000 0.437 0.563
M70.56 Other bursitis of knee-Lower Leg
0.000 0.439 0.561
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.439 0.561
M75.9 Shoulder lesion, unspecified
0.000 0.440 0.560
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.442 0.558
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.442 0.558
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.442 0.558
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.442 0.558
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.442 0.558
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.442 0.558
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.442 0.558
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.443 0.557
K90.9 Intestinal malabsorption, unspecified
0.000 0.445 0.555
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.448 0.552
K90.3 Pancreatic steatorrhoea
0.000 0.449 0.551
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.449 0.551
K90.1 Tropical sprue
0.000 0.449 0.551
M79.5 Residual foreign body in soft tissue
0.000 0.449 0.551
K70-K77 Diseases of liver
0.000 0.450 0.550
E50-E64 Other nutritional deficiencies
0.000 0.450 0.550
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.453 0.547
M77 Other enthesopathies
0.000 0.455 0.545
M05.2 Rheumatoid vasculitis
0.000 0.456 0.544
E85.8 Other amyloidosis
0.000 0.459 0.540
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.459 0.540
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.459 0.540
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.459 0.540
Chapter VIII Diseases of the ear and mastoid process
0.000 0.461 0.539
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.461 0.539
M70.69 Trochanteric bursitis-Site unspec
0.000 0.462 0.538
M70.68 Trochanteric bursitis-Other
0.000 0.462 0.538
M70.67 Trochanteric bursitis-Ankle/Foot
0.000 0.462 0.538
M70.66 Trochanteric bursitis-Lower Leg
0.000 0.462 0.538
M70.64 Trochanteric bursitis-Hand
0.000 0.462 0.538
M70.63 Trochanteric bursitis-Forearm
0.000 0.462 0.538
M70.62 Trochanteric bursitis-Upper arm
0.000 0.462 0.538
M70.61 Trochanteric bursitis-Shldr region
0.000 0.462 0.538
M70.60 Trochanteric bursitis-Mult sites
0.000 0.462 0.538
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.462 0.538
E45 Retarded development following protein-energy malnutrition
0.000 0.462 0.538
E43 Unspecified severe protein-energy malnutrition
0.000 0.462 0.538
E42 Marasmic kwashiorkor
0.000 0.462 0.538
E41 Nutritional marasmus
0.000 0.462 0.538
E40 Kwashiorkor
0.000 0.462 0.538
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.464 0.536
M11.9 Crystal arthropathy, unspecified
0.000 0.464 0.536
M11.1 Familial chondrocalcinosis
0.000 0.464 0.536
M11.0 Hydroxyapatite deposition disease
0.000 0.464 0.536
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.465 0.535
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.465 0.535
H43-H45 Disorders of vitreous body and globe
0.000 0.466 0.534
K74 Fibrosis and cirrhosis of liver
0.000 0.467 0.533
M46 Other inflammatory spondylopathies
0.000 0.467 0.533
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.470 0.530
M94 Other disorders of cartilage
0.000 0.471 0.529
E83.3 Disorders of phosphorus metabolism
0.490 0.473 0.037
K90.8 Other intestinal malabsorption
0.000 0.473 0.527
M79.96 Soft tissue disorder, unspecified (Lower leg)
0.000 0.475 0.525
H27 Other disorders of lens
0.000 0.476 0.524
M71.2 Synovial cyst of popliteal space [Baker]
0.000 0.478 0.522
H35.4 Peripheral retinal degeneration
0.000 0.479 0.521
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.000 0.481 0.519
E89.2 Postprocedural hypoparathyroidism
0.000 0.481 0.519
K74.3 Primary biliary cirrhosis
0.000 0.482 0.518
M60-M63 Disorders of muscles
0.000 0.484 0.516
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.484 0.516
M49.4 Neuropathic spondylopathy
0.000 0.484 0.516
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.484 0.516
M49.2 Enterobacterial spondylitis
0.000 0.484 0.516
M49.1 Brucella spondylitis
0.000 0.484 0.516
M49.0 Tuberculosis of spine
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.486 0.513
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.486 0.513
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.486 0.513
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.486 0.513
E85.4 Organ-limited amyloidosis
0.000 0.487 0.513
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.488 0.512
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.488 0.512
E70.3 Albinism
0.000 0.488 0.512
E70.2 Disorders of tyrosine metabolism
0.000 0.488 0.512
E70.1 Other hyperphenylalaninaemias
0.000 0.488 0.512
E70.0 Classical phenylketonuria
0.000 0.488 0.512
E71.3 Disorders of fatty-acid metabolism
0.000 0.488 0.512
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.488 0.512
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.488 0.512
E71.0 Maple-syrup-urine disease
0.000 0.488 0.512
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.488 0.512
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.488 0.512
E72.5 Disorders of glycine metabolism
0.000 0.488 0.512
E72.4 Disorders of ornithine metabolism
0.000 0.488 0.512
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.488 0.512
E72.2 Disorders of urea cycle metabolism
0.000 0.488 0.512
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.488 0.512
E72.0 Disorders of amino-acid transport
0.000 0.488 0.512
E75.6 Lipid storage disorder, unspecified
0.000 0.488 0.512
E75.5 Other lipid storage disorders
0.000 0.488 0.512
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.488 0.512
E75.3 Sphingolipidosis, unspecified
0.000 0.488 0.512
E75.2 Other sphingolipidosis
0.000 0.488 0.512
E75.1 Other gangliosidosis
0.000 0.488 0.512
E75.0 GM2 gangliosidosis
0.000 0.488 0.512
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.488 0.512
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.488 0.512
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.488 0.512
E76.2 Other mucopolysaccharidoses
0.000 0.488 0.512
E76.1 Mucopolysaccharidosis, type II
0.000 0.488 0.512
E76.0 Mucopolysaccharidosis, type I
0.000 0.488 0.512
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.488 0.512
E77.8 Other disorders of glycoprotein metabolism
0.000 0.488 0.512
E77.1 Defects in glycoprotein degradation
0.000 0.488 0.512
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.488 0.512
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.488 0.512
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.488 0.512
E79.1 Lesch-Nyhan syndrome
0.000 0.488 0.512
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.488 0.512
E85.3 Secondary systemic amyloidosis
0.000 0.488 0.512
L41.9 Parapsoriasis, unspecified
0.000 0.490 0.509
L41.8 Other parapsoriasis
0.000 0.490 0.509
L41.5 Retiform parapsoriasis
0.000 0.490 0.509
L41.4 Large plaque parapsoriasis
0.000 0.490 0.509
L41.3 Small plaque parapsoriasis
0.000 0.490 0.509
L41.2 Lymphomatoid papulosis
0.000 0.490 0.509
L41.1 Pityriasis lichenoides chronica
0.000 0.490 0.509

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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