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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2943659
log Bayes Factor = 19.2683
Chromosome 2   position 227,125,254  (GRCh37) Explore rs2943659 on Ensembl!
Variant rs2943659 is part of Cluster X0034

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.9 Without complications
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.001 0.999
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.002 0.998
E11 Non-insulin-dependent diabetes mellitus
0.000 0.003 0.997
E78.0 Pure hypercholesterolaemia
0.000 0.008 0.992
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.009 0.991
E10-E14 Diabetes mellitus
0.000 0.013 0.987
E10 Insulin-dependent diabetes mellitus
0.000 0.016 0.984
E11.3 With ophthalmic complications
0.000 0.017 0.983
I25.1 Atherosclerotic heart disease
0.000 0.027 0.973
E10.1 With ketoacidosis
0.000 0.028 0.972
E78.5 Hyperlipidaemia, unspecified
0.000 0.035 0.965
I25.5 Ischaemic cardiomyopathy
0.000 0.058 0.942
E78.2 Mixed hyperlipidaemia
0.000 0.062 0.938
E10.5 With peripheral circulatory complications
0.000 0.113 0.887
E78.1 Pure hyperglyceridaemia
0.000 0.128 0.872
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.152 0.848
E78.4 Other hyperlipidaemia
0.000 0.156 0.844
E10.8 With unspecified complications
0.000 0.163 0.837
E13 Other specified diabetes mellitus
0.000 0.165 0.835
E78.8 Other disorders of lipoprotein metabolism
0.000 0.167 0.833
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.190 0.810
E10.9 Without complications
0.000 0.207 0.793
I20-I25 Ischaemic heart diseases
0.000 0.211 0.789
I25.3 Aneurysm of heart
0.000 0.216 0.784
I20.9 Angina pectoris, unspecified
0.000 0.219 0.781
I20 Angina pectoris
0.000 0.221 0.779
I25.2 Old myocardial infarction
0.000 0.228 0.772
E11.4 With neurological complications
0.000 0.244 0.756
E13.9 Without complications
0.000 0.249 0.751
E10.7 With multiple complications
0.000 0.253 0.747
E10.0 With coma
0.000 0.257 0.743
E11.8 With unspecified complications
0.000 0.271 0.729
E11.6 With other specified complications
0.000 0.281 0.719
E11.7 With multiple complications
0.000 0.285 0.714
I25.6 Silent myocardial ischaemia
0.000 0.287 0.713
E12 Malnutrition-related diabetes mellitus
0.000 0.292 0.708
E10.3 With ophthalmic complications
0.000 0.294 0.706
E10.6 With other specified complications
0.000 0.312 0.688
E78.3 Hyperchylomicronaemia
0.000 0.342 0.658
I22 Subsequent myocardial infarction
0.000 0.349 0.651
E10.4 With neurological complications
0.000 0.377 0.623
E78.6 Lipoprotein deficiency
0.000 0.384 0.616
E13.8 With unspecified complications
0.000 0.401 0.599
E13.7 With multiple complications
0.000 0.401 0.599
E13.6 With other specified complications
0.000 0.401 0.599
E13.5 With peripheral circulatory complications
0.000 0.401 0.599
E13.4 With neurological complications
0.000 0.401 0.599
E13.2 With renal complications
0.000 0.401 0.599
E13.1 With ketoacidosis
0.000 0.401 0.599
E13.0 With coma
0.000 0.401 0.599
E11.0 With coma
0.000 0.409 0.591
I20.0 Unstable angina
0.000 0.414 0.586
E11.2 With renal complications
0.000 0.427 0.573
E10.2 With renal complications
0.000 0.430 0.570
E14 Unspecified diabetes mellitus
0.000 0.431 0.569
E11.1 With ketoacidosis
0.000 0.432 0.568
E13.3 With ophthalmic complications
0.000 0.470 0.530
E12.9 Without complications
0.000 0.492 0.507
E12.8 With unspecified complications
0.000 0.492 0.507
E12.7 With multiple complications
0.000 0.492 0.507
E12.6 With other specified complications
0.000 0.492 0.507
E12.5 With peripheral circulatory complications
0.000 0.492 0.507
E12.4 With neurological complications
0.000 0.492 0.507
E12.3 With ophthalmic complications
0.000 0.492 0.507
E12.2 With renal complications
0.000 0.492 0.507
E12.1 With ketoacidosis
0.000 0.492 0.507
E12.0 With coma
0.000 0.492 0.507
I22.8 Subsequent myocardial infarction of other sites
0.000 0.498 0.502
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.500 0.500
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.501 0.499
E14.5 With peripheral circulatory complications
0.000 0.515 0.484
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.532 0.468
E11.5 With peripheral circulatory complications
0.000 0.555 0.445
I25.4 Coronary artery aneurysm
0.001 0.570 0.429
E14.4 With neurological complications
0.000 0.584 0.416
I23 Certain current complications following acute myocardial infarction
0.000 0.588 0.412
E14.8 With unspecified complications
0.000 0.590 0.410
E14.2 Withrenal complications
0.000 0.592 0.408
E14.7 With multiple complications
0.000 0.592 0.408
E14.0 With coma
0.000 0.592 0.408
E14.3 With ophthalmic complications
0.000 0.621 0.379
I20.8 Other forms of angina pectoris
0.000 0.631 0.369
E14.6 With other specified complications
0.000 0.642 0.357
E14.9 Without complications
0.000 0.663 0.337
I60 Subarachnoid haemorrhage
0.000 0.668 0.332
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.670 0.330
I20.1 Angina pectoris with documented spasm
0.000 0.676 0.324
I24 Other acute ischaemic heart diseases
0.000 0.684 0.316
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.698 0.302
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.701 0.299
E14.1 With ketoacidosis
0.000 0.704 0.296
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.704 0.295
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.704 0.295
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.704 0.295
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.704 0.295
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.704 0.295
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.704 0.295
Chapter IX Diseases of the circulatory system
0.000 0.707 0.293
I60-I69 Cerebrovascular diseases
0.000 0.709 0.291
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.712 0.288
I10-I15 Hypertensive diseases
0.000 0.719 0.281
I10 Essential (primary) hypertension
0.000 0.721 0.279
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.001 0.741 0.259
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.741 0.259
I24.1 Dressler's syndrome
0.000 0.747 0.253
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.747 0.253
I62 Other nontraumatic intracranial haemorrhage
0.000 0.749 0.251
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.751 0.249
E70-E90 Metabolic disorders
0.000 0.753 0.247
I05-I09 Chronic rheumatic heart diseases
0.000 0.754 0.246
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.756 0.244
I67 Other cerebrovascular diseases
0.000 0.758 0.242
I60.8 Other subarachnoid haemorrhage
0.000 0.760 0.240
I67.1 Cerebral aneurysm, nonruptured
0.000 0.760 0.240
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.761 0.238
I05 Rheumatic mitral valve diseases
0.000 0.768 0.232
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.772 0.228
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.774 0.226
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.778 0.222
I05.2 Mitral stenosis with insufficiency
0.000 0.785 0.215
I12 Hypertensive renal disease
0.000 0.788 0.212
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.789 0.211
E16 Other disorders of pancreatic internal secretion
0.000 0.791 0.209
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.793 0.206
I23.8 Other current complications following acute myocardial infarction
0.001 0.794 0.205
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.796 0.204
I13 Hypertensive heart and renal disease
0.000 0.798 0.201
I00-I02 Acute rheumatic fever
0.000 0.801 0.199
E73 Lactose intolerance
0.000 0.802 0.198
I24.8 Other forms of acute ischaemic heart disease
0.000 0.803 0.197
E16.2 Hypoglycaemia, unspecified
0.000 0.804 0.196
I61 Intracerebral haemorrhage
0.000 0.809 0.191
I67.2 Cerebral atherosclerosis
0.000 0.810 0.190
E85 Amyloidosis
0.000 0.813 0.187
I12.0 Hypertensive renal disease with renal failure
0.000 0.815 0.185
I05.1 Rheumatic mitral insufficiency
0.000 0.818 0.182
I62.1 Nontraumatic extradural haemorrhage
0.000 0.820 0.180
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.821 0.178
E79 Disorders of purine and pyrimidine metabolism
0.000 0.823 0.177
E77 Disorders of glycoprotein metabolism
0.000 0.823 0.177
E76 Disorders of glycosaminoglycan metabolism
0.000 0.823 0.177
E72 Other disorders of amino-acid metabolism
0.000 0.823 0.177
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.823 0.177
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.823 0.177
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.823 0.177
I05.9 Mitral valve disease, unspecified
0.000 0.824 0.176
I09 Other rheumatic heart diseases
0.000 0.826 0.174
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.826 0.174
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.826 0.174
I67.5 Moyamoya disease
0.000 0.826 0.174
I67.4 Hypertensive encephalopathy
0.000 0.826 0.174
I67.3 Progressive vascular leukoencephalopathy
0.000 0.826 0.174
I68.0 Cerebral amyloid angiopathy
0.000 0.827 0.172
I08 Multiple valve diseases
0.000 0.830 0.170
I07 Rheumatic tricuspid valve diseases
0.000 0.831 0.169
I05.0 Mitral stenosis
0.000 0.834 0.166
I05.8 Other mitral valve diseases
0.000 0.834 0.166
E70 Disorders of aromatic amino-acid metabolism
0.000 0.835 0.165
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.835 0.165
E73.9 Lactose intolerance, unspecified
0.000 0.836 0.164
E15 Nondiabetic hypoglycaemic coma
0.000 0.838 0.162
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.841 0.159
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.841 0.159
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.841 0.159
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.841 0.159
E85.4 Organ-limited amyloidosis
0.000 0.842 0.158
I15 Secondary hypertension
0.000 0.842 0.158
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.842 0.158
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.843 0.157
I21 Acute myocardial infarction
0.000 0.844 0.156
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.844 0.156
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.845 0.155
E84 Cystic fibrosis
0.000 0.846 0.154
I08.8 Other multiple valve diseases
0.000 0.848 0.152
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.850 0.150
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.850 0.150
E16.4 Abnormal secretion of gastrin
0.000 0.850 0.150
E16.3 Increased secretion of glucagon
0.000 0.850 0.150
I11 Hypertensive heart disease
0.000 0.850 0.149
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.852 0.148
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.852 0.148
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.852 0.148
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.852 0.147
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.853 0.147
E74 Other disorders of carbohydrate metabolism
0.000 0.854 0.146
E16.1 Other hypoglycaemia
0.000 0.854 0.146
I08.0 Disorders of both mitral and aortic valves
0.000 0.855 0.145
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.855 0.145
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.855 0.145
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.855 0.145
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.855 0.145
I21.4 Acute subendocardial myocardial infarction
0.000 0.857 0.143
I02 Rheumatic chorea
0.000 0.857 0.143
I01 Rheumatic fever with heart involvement
0.000 0.857 0.143
E73.8 Other lactose intolerance
0.000 0.857 0.142
E73.1 Secondary lactase deficiency
0.000 0.857 0.142
E73.0 Congenital lactase deficiency
0.000 0.857 0.142
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.859 0.141
E85.9 Amyloidosis, unspecified
0.000 0.860 0.140
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.861 0.138
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.862 0.138
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.865 0.134
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.865 0.134
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.865 0.134
E88 Other metabolic disorders
0.000 0.868 0.132
I00 Rheumatic fever without mention of heart involvement
0.000 0.869 0.131
E75.5 Other lipid storage disorders
0.000 0.870 0.129
E75.6 Lipid storage disorder, unspecified
0.000 0.872 0.128
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.872 0.128
E75.3 Sphingolipidosis, unspecified
0.000 0.872 0.128
E75.2 Other sphingolipidosis
0.000 0.872 0.128
E75.1 Other gangliosidosis
0.000 0.872 0.128
E75.0 GM2 gangliosidosis
0.000 0.872 0.128
E85.3 Secondary systemic amyloidosis
0.000 0.872 0.128
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.872 0.127
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.873 0.127
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.873 0.127
E79.1 Lesch-Nyhan syndrome
0.000 0.873 0.127
E71.3 Disorders of fatty-acid metabolism
0.000 0.873 0.127
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.873 0.127
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.873 0.127
E71.0 Maple-syrup-urine disease
0.000 0.873 0.127
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.873 0.127
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.873 0.127
E72.5 Disorders of glycine metabolism
0.000 0.873 0.127
E72.4 Disorders of ornithine metabolism
0.000 0.873 0.127
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.873 0.127
E72.2 Disorders of urea cycle metabolism
0.000 0.873 0.127
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.873 0.127
E72.0 Disorders of amino-acid transport
0.000 0.873 0.127
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.873 0.127
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.873 0.127
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.873 0.127
E76.2 Other mucopolysaccharidoses
0.000 0.873 0.127
E76.1 Mucopolysaccharidosis, type II
0.000 0.873 0.127
E76.0 Mucopolysaccharidosis, type I
0.000 0.873 0.127
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.873 0.127
E77.8 Other disorders of glycoprotein metabolism
0.000 0.873 0.127
E77.1 Defects in glycoprotein degradation
0.000 0.873 0.127
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.873 0.127
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.873 0.127
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.874 0.126
I09.8 Other specified rheumatic heart diseases
0.000 0.875 0.125
I09.2 Chronic rheumatic pericarditis
0.000 0.875 0.125
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.875 0.125
I09.0 Rheumatic myocarditis
0.000 0.875 0.125
E80.2 Other porphyria
0.000 0.875 0.125
I09.9 Rheumatic heart disease, unspecified
0.000 0.877 0.123
I08.9 Multiple valve disease, unspecified
0.000 0.877 0.123
I07.9 Tricuspid valve disease, unspecified
0.000 0.878 0.122
I07.8 Other tricuspid valve diseases
0.000 0.878 0.122
I07.2 Tricuspid stenosis with insufficiency
0.000 0.878 0.122
I07.0 Tricuspid stenosis
0.000 0.878 0.122
E40-E46 Malnutrition
0.000 0.878 0.121
I06 Rheumatic aortic valve diseases
0.001 0.880 0.120
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.881 0.118
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.881 0.118
E70.2 Disorders of tyrosine metabolism
0.000 0.881 0.118
E70.1 Other hyperphenylalaninaemias
0.000 0.881 0.118
E70.0 Classical phenylketonuria
0.000 0.881 0.118
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.884 0.116
E80.6 Other disorders of bilirubin metabolism
0.000 0.884 0.116
I07.1 Tricuspid insufficiency
0.000 0.886 0.114
I15.2 Hypertension secondary to endocrine disorders
0.000 0.886 0.113
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.888 0.112
I15.8 Other secondary hypertension
0.000 0.889 0.111
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.889 0.111
E80.5 Crigler-Najjar syndrome
0.000 0.889 0.111
E80.3 Defects of catalase and peroxydase
0.000 0.889 0.111
E80.0 Hereditary erythropoietic porphyria
0.000 0.889 0.111
E85.8 Other amyloidosis
0.000 0.889 0.111
E84.8 Cystic fibrosis with other manifestations
0.000 0.889 0.110
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.889 0.110
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.889 0.110
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.890 0.110
E80.1 Porphyria cutanea tarda
0.000 0.891 0.109
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.891 0.109
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.108 0.892 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.893 0.107
I61.8 Other intracerebral haemorrhage
0.000 0.893 0.107
E70.3 Albinism
0.000 0.893 0.106
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.893 0.106
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.894 0.106
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.894 0.106
I15.1 Hypertension secondary to other renal disorders
0.000 0.895 0.105
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.895 0.105
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.895 0.105
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.895 0.105
E74.2 Disorders of galactose metabolism
0.000 0.895 0.105
E74.1 Disorders of fructose metabolism
0.000 0.895 0.105
E74.0 Glycogen storage disease
0.000 0.895 0.105
F23 Acute and transient psychotic disorders
0.105 0.895 0.000
I12.9 Hypertensive renal disease without renal failure
0.000 0.897 0.103
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.897 0.102
I01.8 Other acute rheumatic heart disease
0.000 0.897 0.102
I01.2 Acute rheumatic myocarditis
0.000 0.897 0.102
I01.1 Acute rheumatic endocarditis
0.000 0.897 0.102
I01.0 Acute rheumatic pericarditis
0.000 0.897 0.102
I02.9 Rheumatic chorea without heart involvement
0.000 0.897 0.102
I02.0 Rheumatic chorea with heart involvement
0.000 0.897 0.102
I15.0 Renovascular hypertension
0.000 0.897 0.102
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.899 0.101
I15.9 Seconday hypertension, unspecified
0.000 0.899 0.101
F20 Schizophrenia
0.100 0.900 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.099 0.901 0.000
F29 Unspecified nonorganic psychosis
0.099 0.901 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.903 0.097
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.903 0.096
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.905 0.095
E88.9 Metabolic disorder, unspecified
0.000 0.905 0.094
F20.0 Paranoid schizophrenia
0.094 0.906 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.907 0.093
I65.1 Occlusion and stenosis of basilar artery
0.000 0.907 0.093
F25 Schizoaffective disorders
0.091 0.909 0.000
E88.3 Tumour lysis syndrome
0.000 0.909 0.090
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.910 0.090
E50-E64 Other nutritional deficiencies
0.000 0.911 0.089
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.912 0.088
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.913 0.087
E45 Retarded development following protein-energy malnutrition
0.000 0.913 0.087
E43 Unspecified severe protein-energy malnutrition
0.000 0.913 0.087
E42 Marasmic kwashiorkor
0.000 0.913 0.087
E41 Nutritional marasmus
0.000 0.913 0.087
E40 Kwashiorkor
0.000 0.913 0.087
E84.9 Cystic fibrosis, unspecified
0.000 0.913 0.087
E88.8 Other specified metabolic disorders
0.000 0.913 0.087
E88.2 Lipomatosis, not elsewhere classified
0.000 0.913 0.087
I06.9 Rheumatic aortic valve disease, unspecified
0.001 0.913 0.086
I06.8 Other rheumatic aortic valve diseases
0.001 0.913 0.086
I06.2 Rheumatic aortic stenosis with insufficiency
0.001 0.913 0.086
F23.3 Other acute predominantly delusional psychotic disorders
0.086 0.914 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.914 0.086
F22 Persistent delusional disorders
0.086 0.914 0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.085 0.915 0.000
F20.9 Schizophrenia, unspecified
0.084 0.915 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.916 0.084
F25.9 Schizoaffective disorder, unspecified
0.080 0.920 0.000
I67.8 Other specified cerebrovascular diseases
0.000 0.921 0.079
I78 Diseases of capillaries
0.000 0.922 0.078
I28 Other diseases of pulmonary vessels
0.000 0.922 0.078
F28 Other nonorganic psychotic disorders
0.077 0.923 0.000
F24 Induced delusional disorder
0.077 0.923 0.000
F21 Schizotypal disorder
0.077 0.923 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.923 0.077
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.923 0.077
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.923 0.077
F23.8 Other acute and transient psychotic disorders
0.075 0.924 0.000
F23.2 Acute schizophrenia-like psychotic disorder
0.075 0.924 0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia
0.075 0.924 0.000
Chapter V Mental and behavioural disorders
0.075 0.925 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.075 0.925 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.926 0.074
I63 Cerebral infarction
0.000 0.926 0.074
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.927 0.073
F20.8 Other schizophrenia
0.072 0.928 0.000
F25.2 Schizoaffective disorder, mixed type
0.072 0.928 0.000
F20.6 Simple schizophrenia
0.072 0.928 0.000
F20.4 Postschizophrenic depression
0.072 0.928 0.000
F20.3 Undifferentiated schizophrenia
0.072 0.928 0.000
F20.2 Catatonic schizophrenia
0.072 0.928 0.000
F20.1 Hebephrenic schizophrenia
0.072 0.928 0.000
F60-F69 Disorders of adult personality and behaviour
0.071 0.929 0.000
F45 Somatoform disorders
0.070 0.930 0.000
I06.1 Rheumatic aortic insufficiency
0.001 0.930 0.069
F44 Dissociative [conversion] disorders
0.069 0.931 0.000
F40 Phobic anxiety disorders
0.069 0.931 0.000
F60.9 Personality disorder, unspecified
0.069 0.931 0.000
F60 Specific personality disorders
0.069 0.931 0.000
F22.0 Delusional disorder
0.068 0.932 0.000
I70 Atherosclerosis
0.000 0.933 0.067
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.933 0.067
E89.2 Postprocedural hypoparathyroidism
0.000 0.933 0.067
F25.8 Other schizoaffective disorders
0.066 0.934 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.934 0.066
F22.9 Persistent delusional disorder, unspecified
0.065 0.935 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.936 0.064
E63 Other nutritional deficiencies
0.000 0.936 0.064
E50 Vitamin A deficiency
0.000 0.936 0.064
E60 Dietary zinc deficiency
0.000 0.936 0.064
E59 Dietary selenium deficiency
0.000 0.936 0.064
E52 Niacin deficiency [pellagra]
0.000 0.936 0.064
E56 Other vitamin deficiencies
0.000 0.936 0.064
I78.1 Naevus, nonneoplastic
0.000 0.936 0.064
F25.1 Schizoaffective disorder, depressive type
0.064 0.936 0.000
F40.0 Agoraphobia
0.064 0.936 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.936 0.064
I69 Sequelae of cerebrovascular disease
0.000 0.936 0.064
E44.1 Mild protein-energy malnutrition
0.000 0.937 0.062
E44.0 Moderate protein-energy malnutrition
0.000 0.937 0.062
E51 Thiamine deficiency
0.000 0.938 0.062
E58 Dietary calcium deficiency
0.000 0.938 0.062
F80-F89 Disorders of psychological development
0.062 0.938 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.938 0.062
E89.1 Postprocedural hypoinsulinaemia
0.000 0.938 0.062
F22.8 Other persistent delusional disorders
0.062 0.938 0.000
I28.8 Other specified diseases of pulmonary vessels
0.000 0.939 0.061
I06.0 Rheumatic aortic stenosis
0.001 0.939 0.060
E67 Other hyperalimentation
0.000 0.939 0.061
E68 Sequelae of hyperalimentation
0.000 0.939 0.061
F45.8 Other somatoform disorders
0.060 0.940 0.000
I72 Other aneurysm
0.000 0.940 0.060
F44.9 Dissociative [conversion] disorder, unspecified
0.059 0.941 0.000
F70-F79 Mental retardation
0.059 0.941 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.941 0.059
F25.0 Schizoaffective disorder, manic type
0.059 0.941 0.000
E61 Deficiency of other nutrient elements
0.000 0.941 0.059
F69 Unspecified disorder of adult personality and behaviour
0.058 0.941 0.000
F81 Specific developmental disorders of scholastic skills
0.058 0.941 0.000
F45.0 Somatisation disorder
0.058 0.942 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.942 0.058
F45.9 Somatoform disorder, unspecified
0.057 0.943 0.000
I26 Pulmonary embolism
0.000 0.943 0.057
F44.0 Dissociative amnesia
0.056 0.943 0.000
I78.9 Disease of capillaries, unspecified
0.000 0.944 0.056
E53 Deficiency of other B group vitamins
0.000 0.944 0.056
I78.8 Other diseases of capillaries
0.000 0.944 0.056
F81.9 Developmental disorder of scholastic skills, unspecified
0.056 0.944 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.944 0.056
I28.1 Aneurysm of pulmonary artery
0.000 0.944 0.056
F60.8 Other specific personality disorders
0.056 0.944 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.056 0.944 0.000
F45.3 Somatoform autonomic dysfunction
0.056 0.944 0.000
F44.8 Other dissociative [conversion] disorders
0.055 0.945 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.945 0.055
F40.2 Specific (isolated) phobias
0.055 0.945 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.945 0.055
F48 Other neurotic disorders
0.054 0.945 0.000
I70.1 Atherosclerosis of renal artery
0.000 0.946 0.054
I74 Arterial embolism and thrombosis
0.000 0.946 0.054
F45.4 Persistent somatoform pain disorder
0.054 0.946 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.054 0.946 0.000
F60.2 Dissocial personality disorder
0.054 0.946 0.000
E89.5 Postprocedural testicular hypofunction
0.000 0.946 0.053
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.946 0.053
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.946 0.053
E89.0 Postprocedural hypothyroidism
0.000 0.947 0.053
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.947 0.053
F44.4 Dissociative motor disorders
0.053 0.947 0.000
E89.4 Postprocedural ovarian failure
0.000 0.947 0.053
F60.0 Paranoid personality disorder
0.053 0.947 0.000
F99-F99 Unspecified mental disorder
0.053 0.947 0.000
F20.5 Residual schizophrenia
0.052 0.948 0.000
I63.8 Other cerebral infarction
0.000 0.948 0.052
F60.7 Dependent personality disorder
0.051 0.949 0.000
F68 Other disorders of adult personality and behaviour
0.051 0.949 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.051 0.949 0.000
F65 Disorders of sexual preference
0.051 0.949 0.000
F63 Habit and impulse disorders
0.051 0.949 0.000
F61 Mixed and other personality disorders
0.051 0.949 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.949 0.051
E54 Ascorbic acid deficiency
0.000 0.949 0.051
F40.8 Other phobic anxiety disorders
0.051 0.949 0.000
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.949 0.051
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.949 0.050
F45.1 Undifferentiated somatoform disorder
0.050 0.949 0.000
F40.9 Phobic anxiety disorder, unspecified
0.050 0.950 0.000
F44.5 Dissociative convulsions
0.050 0.950 0.000
F40.1 Social phobias
0.050 0.950 0.000
F44.7 Mixed dissociative [conversion] disorders
0.050 0.950 0.000
F44.6 Dissociative anaesthesia and sensory loss
0.050 0.950 0.000
F44.3 Trance and possession disorders
0.050 0.950 0.000
F44.2 Dissociative stupor
0.050 0.950 0.000
F44.1 Dissociative fugue
0.050 0.950 0.000
E80.4 Gilbert's syndrome
0.000 0.950 0.050
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.950 0.050
F60.4 Histrionic personality disorder
0.050 0.950 0.000
F60.1 Schizoid personality disorder
0.050 0.950 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.050 0.950 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.951 0.049
E53.9 Vitamin B deficiency, unspecified
0.000 0.951 0.049
I74.8 Embolism and thrombosis of other arteries
0.000 0.951 0.049
E55 Vitamin D deficiency
0.000 0.951 0.049
F42 Obsessive-compulsive disorder
0.049 0.951 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.952 0.048
E65 Localised adiposity
0.000 0.952 0.048
F79 Unspecified mental retardation
0.048 0.952 0.000
F51 Nonorganic sleep disorders
0.048 0.952 0.000
I70.8 Atherosclerosis of other arteries
0.000 0.952 0.047
I79.1 Aortitis in diseases classified elsewhere
0.000 0.953 0.047
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.953 0.047
I74.5 Embolism and thrombosis of iliac artery
0.000 0.953 0.047
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.953 0.047
I72.8 Aneurysm of other specified arteries
0.000 0.953 0.047
F60.5 Anankastic personality disorder
0.046 0.953 0.000
I72.0 Aneurysm of carotid artery
0.000 0.953 0.047
E50.9 Vitamin A deficiency, unspecified
0.000 0.954 0.046
E50.8 Other manifestations of vitamin A deficiency
0.000 0.954 0.046
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.954 0.046
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.954 0.046
E50.5 Vitamin A deficiency with night blindness
0.000 0.954 0.046
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.954 0.046
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.954 0.046
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.954 0.046
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.954 0.046
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.954 0.046
E63.9 Nutritional deficiency, unspecified
0.000 0.954 0.046
E63.8 Other specified nutritional deficiencies
0.000 0.954 0.046
E63.1 Imbalance of constituents of food intake
0.000 0.954 0.046

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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