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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs295
log Bayes Factor = 5.95375
Chromosome 8   position 19,816,238  (GRCh37) Explore rs295 on Ensembl!
Variant rs295 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.001 0.999
I21 Acute myocardial infarction
0.000 0.003 0.997
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.004 0.996
I22 Subsequent myocardial infarction
0.000 0.009 0.991
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.028 0.972
I21.9 Acute myocardial infarction, unspecified
0.000 0.029 0.971
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.044 0.956
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.064 0.936
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.070 0.930
E78.0 Pure hypercholesterolaemia
0.000 0.074 0.926
I25.2 Old myocardial infarction
0.000 0.078 0.922
E78.2 Mixed hyperlipidaemia
0.000 0.082 0.918
E78.5 Hyperlipidaemia, unspecified
0.000 0.091 0.909
I77 Other disorders of arteries and arterioles
0.000 0.104 0.896
I77.1 Stricture of artery
0.000 0.105 0.895
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.107 0.893
I25.4 Coronary artery aneurysm
0.000 0.109 0.891
I21.4 Acute subendocardial myocardial infarction
0.000 0.133 0.867
I71 Aortic aneurysm and dissection
0.000 0.140 0.860
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.142 0.858
I73 Other peripheral vascular diseases
0.000 0.143 0.857
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.153 0.847
I24 Other acute ischaemic heart diseases
0.000 0.160 0.840
I73.9 Peripheral vascular disease, unspecified
0.000 0.161 0.839
E78.1 Pure hyperglyceridaemia
0.000 0.166 0.834
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.182 0.818
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.191 0.809
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.210 0.790
I70 Atherosclerosis
0.000 0.210 0.790
I77.8 Other specified disorders of arteries and arterioles
0.000 0.213 0.787
E78.4 Other hyperlipidaemia
0.000 0.218 0.782
I73.8 Other specified peripheral vascular diseases
0.000 0.227 0.773
I71.0 Dissection of aorta [any part]
0.000 0.242 0.758
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.244 0.756
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.252 0.748
I77.0 Arteriovenous fistula, acquired
0.000 0.270 0.730
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.278 0.722
Chapter IX Diseases of the circulatory system
0.000 0.283 0.717
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.285 0.715
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.296 0.704
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.310 0.690
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.311 0.689
I23 Certain current complications following acute myocardial infarction
0.000 0.320 0.679
I77.2 Rupture of artery
0.000 0.330 0.670
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.333 0.667
E78.3 Hyperchylomicronaemia
0.000 0.333 0.667
I25.5 Ischaemic cardiomyopathy
0.000 0.334 0.666
E78.6 Lipoprotein deficiency
0.000 0.342 0.658
I77.5 Necrosis of artery
0.000 0.358 0.642
I77.4 Coeliac artery compression syndrome
0.000 0.358 0.642
I77.3 Arterial fibromuscular dysplasia
0.000 0.358 0.642
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.368 0.632
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.384 0.616
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.384 0.616
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.384 0.616
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.384 0.616
I70.1 Atherosclerosis of renal artery
0.000 0.393 0.607
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.419 0.581
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.420 0.580
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.420 0.580
I79.1 Aortitis in diseases classified elsewhere
0.000 0.420 0.580
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.420 0.580
I70.0 Atherosclerosis of aorta
0.000 0.430 0.570
I70.9 Generalised and unspecified atherosclerosis
0.000 0.434 0.566
I25.3 Aneurysm of heart
0.000 0.444 0.556
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.445 0.555
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.450 0.549
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.461 0.539
I74 Arterial embolism and thrombosis
0.000 0.465 0.535
E78.8 Other disorders of lipoprotein metabolism
0.000 0.493 0.507
I24.1 Dressler's syndrome
0.000 0.498 0.502
I00-I02 Acute rheumatic fever
0.000 0.500 0.500
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.513 0.487
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.513 0.487
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.513 0.487
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.513 0.487
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.513 0.487
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.513 0.487
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.513 0.487
I70.8 Atherosclerosis of other arteries
0.000 0.513 0.487
I24.8 Other forms of acute ischaemic heart disease
0.000 0.514 0.486
I78 Diseases of capillaries
0.000 0.514 0.485
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.523 0.476
I20 Angina pectoris
0.000 0.525 0.475
I22.8 Subsequent myocardial infarction of other sites
0.000 0.527 0.473
I74.8 Embolism and thrombosis of other arteries
0.000 0.539 0.461
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.545 0.455
I23.8 Other current complications following acute myocardial infarction
0.000 0.550 0.450
I77.6 Arteritis, unspecified
0.000 0.554 0.446
I25.6 Silent myocardial ischaemia
0.001 0.556 0.443
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.564 0.435
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.568 0.432
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.576 0.424
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.588 0.412
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.591 0.408
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.594 0.406
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.594 0.406
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.612 0.388
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.614 0.386
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.625 0.375
I20.9 Angina pectoris, unspecified
0.000 0.626 0.374
I20.0 Unstable angina
0.000 0.636 0.364
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.636 0.364
I97.1 Other functional disturbances following cardiac surgery
0.000 0.637 0.363
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.639 0.361
I02 Rheumatic chorea
0.000 0.641 0.359
I01 Rheumatic fever with heart involvement
0.000 0.641 0.359
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.650 0.349
I78.9 Disease of capillaries, unspecified
0.000 0.652 0.348
I00 Rheumatic fever without mention of heart involvement
0.000 0.655 0.344
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.691 0.309
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.691 0.309
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.696 0.304
I97.0 Postcardiotomy syndrome
0.000 0.696 0.304
I74.5 Embolism and thrombosis of iliac artery
0.000 0.696 0.304
I78.8 Other diseases of capillaries
0.000 0.707 0.293
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.713 0.287
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.715 0.285
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.716 0.284
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.724 0.275
I70.80 Atherosclerosis of other arteries (without gangrene)
0.001 0.729 0.270
I99 Other and unspecified disorders of circulatory system
0.000 0.739 0.261
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.743 0.257
I01.8 Other acute rheumatic heart disease
0.000 0.743 0.257
I01.2 Acute rheumatic myocarditis
0.000 0.743 0.257
I01.1 Acute rheumatic endocarditis
0.000 0.743 0.257
I01.0 Acute rheumatic pericarditis
0.000 0.743 0.257
I02.9 Rheumatic chorea without heart involvement
0.000 0.743 0.257
I02.0 Rheumatic chorea with heart involvement
0.000 0.743 0.257
I72 Other aneurysm
0.000 0.750 0.249
I05-I09 Chronic rheumatic heart diseases
0.000 0.761 0.239
I20.1 Angina pectoris with documented spasm
0.000 0.771 0.228
I28 Other diseases of pulmonary vessels
0.000 0.772 0.228
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.794 0.205
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.802 0.198
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.802 0.198
I98.0 Cardiovascular syphilis
0.000 0.802 0.198
I78.1 Naevus, nonneoplastic
0.000 0.807 0.193
I72.2 Aneurysm of renal artery
0.000 0.812 0.188
I72.4 Aneurysm of artery of lower extremity
0.000 0.815 0.185
I07 Rheumatic tricuspid valve diseases
0.000 0.817 0.183
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.821 0.179
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.821 0.179
I26 Pulmonary embolism
0.000 0.824 0.176
I09 Other rheumatic heart diseases
0.000 0.827 0.173
I28.8 Other specified diseases of pulmonary vessels
0.000 0.830 0.170
I72.9 Aneurysm of unspecified site
0.000 0.831 0.169
I72.1 Aneurysm of artery of upper extremity
0.000 0.833 0.166
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.835 0.165
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.836 0.164
I28.1 Aneurysm of pulmonary artery
0.000 0.836 0.164
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.836 0.164
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.851 0.149
I06 Rheumatic aortic valve diseases
0.000 0.851 0.148
I20.8 Other forms of angina pectoris
0.000 0.853 0.147
I72.3 Aneurysm of iliac artery
0.000 0.854 0.145
I07.1 Tricuspid insufficiency
0.000 0.858 0.142
I05 Rheumatic mitral valve diseases
0.000 0.860 0.140
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.867 0.133
I07.9 Tricuspid valve disease, unspecified
0.000 0.869 0.131
I07.8 Other tricuspid valve diseases
0.000 0.869 0.131
I07.2 Tricuspid stenosis with insufficiency
0.000 0.869 0.131
I07.0 Tricuspid stenosis
0.000 0.869 0.131
I09.9 Rheumatic heart disease, unspecified
0.000 0.874 0.125
I09.8 Other specified rheumatic heart diseases
0.000 0.876 0.124
I09.2 Chronic rheumatic pericarditis
0.000 0.876 0.124
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.876 0.124
I09.0 Rheumatic myocarditis
0.000 0.876 0.124
I05.1 Rheumatic mitral insufficiency
0.000 0.883 0.117
I72.0 Aneurysm of carotid artery
0.001 0.893 0.107
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.893 0.106
I06.8 Other rheumatic aortic valve diseases
0.000 0.893 0.106
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.893 0.106
I06.1 Rheumatic aortic insufficiency
0.000 0.893 0.106
I72.8 Aneurysm of other specified arteries
0.001 0.896 0.103
I05.8 Other mitral valve diseases
0.000 0.900 0.100
I27 Other pulmonary heart diseases
0.000 0.900 0.100
I05.0 Mitral stenosis
0.000 0.907 0.093
I95 Hypotension
0.000 0.915 0.085
I06.0 Rheumatic aortic stenosis
0.001 0.917 0.083
I10-I15 Hypertensive diseases
0.000 0.918 0.082
I05.2 Mitral stenosis with insufficiency
0.000 0.923 0.077
I05.9 Mitral valve disease, unspecified
0.000 0.925 0.075
I27.8 Other specified pulmonary heart diseases
0.000 0.928 0.072
I27.1 Kyphoscoliotic heart disease
0.000 0.928 0.072
I95.8 Other hypotension
0.000 0.935 0.065
I27.9 Pulmonary heart disease, unspecified
0.000 0.936 0.064
I73.0 Raynaud's syndrome
0.000 0.942 0.058
I95.0 Idiopathic hypotension
0.000 0.943 0.056
I11 Hypertensive heart disease
0.000 0.944 0.056
I13 Hypertensive heart and renal disease
0.000 0.944 0.055
I27.0 Primary pulmonary hypertension
0.000 0.950 0.050
I95.1 Orthostatic hypotension
0.000 0.952 0.048
I15 Secondary hypertension
0.000 0.954 0.045
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.955 0.044
G50.0 Trigeminal neuralgia
0.000 0.958 0.042
N90.4 Leukoplakia of vulva
0.000 0.960 0.040
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.960 0.040
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.960 0.040
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.960 0.040
N90 Other noninflammatory disorders of vulva and perineum
0.000 0.960 0.040
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.000 0.961 0.039
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.963 0.036
N90.7 Vulvar cyst
0.000 0.963 0.037
N90.5 Atrophy of vulva
0.000 0.964 0.036
N90.6 Hypertrophy of vulva
0.000 0.966 0.034
I15.8 Other secondary hypertension
0.000 0.967 0.033
I15.2 Hypertension secondary to endocrine disorders
0.000 0.967 0.033
I15.1 Hypertension secondary to other renal disorders
0.000 0.967 0.033
I27.2 Other secondary pulmonary hypertension
0.000 0.967 0.032
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.968 0.032
N90.1 Moderate vulvar dysplasia
0.000 0.969 0.031
I08 Multiple valve diseases
0.000 0.970 0.029
N90.2 Severe vulvar dysplasia, not elsewhere classified
0.000 0.971 0.029
N90.0 Mild vulvar dysplasia
0.000 0.971 0.029
I15.0 Renovascular hypertension
0.000 0.972 0.027
I15.9 Seconday hypertension, unspecified
0.000 0.973 0.027
I08.8 Other multiple valve diseases
0.000 0.975 0.025
N90.3 Dysplasia of vulva, unspecified
0.000 0.975 0.025
I95.2 Hypotension due to drugs
0.000 0.975 0.025
I08.9 Multiple valve disease, unspecified
0.000 0.977 0.022
R16.1 Splenomegaly, not elsewhere classified
0.019 0.981 0.000
I12 Hypertensive renal disease
0.000 0.982 0.018
I95.9 Hypotension, unspecified
0.000 0.983 0.017
G50 Disorders of trigeminal nerve
0.000 0.983 0.017
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.000 0.984 0.016
I08.2 Disorders of both aortic and tricuspid valves
0.001 0.986 0.013
G50.1 Atypical facial pain
0.000 0.987 0.013
G50.8 Other disorders of trigeminal nerve
0.000 0.987 0.012
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.988 0.011
G50.9 Disorder of trigeminal nerve, unspecified
0.000 0.989 0.011
E70-E90 Metabolic disorders
0.000 0.989 0.011
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.990 0.010
I63 Cerebral infarction
0.000 0.991 0.009
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.009 0.991 0.000
E85 Amyloidosis
0.000 0.991 0.009
K08.3 Retained dental root
0.000 0.991 0.009
E73 Lactose intolerance
0.000 0.991 0.009
I60-I69 Cerebrovascular diseases
0.000 0.992 0.008
E79 Disorders of purine and pyrimidine metabolism
0.000 0.992 0.008
E74 Other disorders of carbohydrate metabolism
0.000 0.992 0.008
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.992 0.008
E84 Cystic fibrosis
0.000 0.992 0.008
E77 Disorders of glycoprotein metabolism
0.000 0.992 0.008
E76 Disorders of glycosaminoglycan metabolism
0.000 0.992 0.008
E72 Other disorders of amino-acid metabolism
0.000 0.992 0.008
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.992 0.008
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.992 0.008
E88 Other metabolic disorders
0.000 0.992 0.008
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.992 0.008
I63.8 Other cerebral infarction
0.000 0.992 0.008
E73.9 Lactose intolerance, unspecified
0.000 0.993 0.007
E85.4 Organ-limited amyloidosis
0.000 0.993 0.007
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.993 0.007
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified
0.007 0.993 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.993 0.007
E85.3 Secondary systemic amyloidosis
0.000 0.993 0.007
E70 Disorders of aromatic amino-acid metabolism
0.000 0.993 0.007
H74.3 Other acquired abnormalities of ear ossicles
0.000 0.993 0.007
H74.9 Disorder of middle ear and mastoid, unspecified
0.000 0.993 0.007
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.993 0.007
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.993 0.007
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.993 0.007
E85.8 Other amyloidosis
0.000 0.993 0.007
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.993 0.007
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.993 0.007
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.993 0.007
E73.8 Other lactose intolerance
0.000 0.993 0.006
E73.1 Secondary lactase deficiency
0.000 0.993 0.006
E73.0 Congenital lactase deficiency
0.000 0.993 0.006
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.993 0.006
H74 Other disorders of middle ear and mastoid
0.000 0.994 0.006
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.994 0.006
R16.0 Hepatomegaly, not elsewhere classified
0.006 0.994 0.000
E85.9 Amyloidosis, unspecified
0.000 0.994 0.006
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.994 0.006
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.994 0.006
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.994 0.006
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.994 0.006
E79.1 Lesch-Nyhan syndrome
0.000 0.994 0.006
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.994 0.006
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.994 0.006
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.994 0.006
E74.2 Disorders of galactose metabolism
0.000 0.994 0.006
E74.1 Disorders of fructose metabolism
0.000 0.994 0.006
E74.0 Glycogen storage disease
0.000 0.994 0.006
H72 Perforation of tympanic membrane
0.000 0.994 0.006
H72.0 Central perforation of tympanic membrane
0.000 0.994 0.006
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.994 0.006
E71.3 Disorders of fatty-acid metabolism
0.000 0.994 0.006
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.994 0.006
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.994 0.006
E71.0 Maple-syrup-urine disease
0.000 0.994 0.006
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.994 0.006
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.994 0.006
E72.5 Disorders of glycine metabolism
0.000 0.994 0.006
E72.4 Disorders of ornithine metabolism
0.000 0.994 0.006
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.994 0.006
E72.2 Disorders of urea cycle metabolism
0.000 0.994 0.006
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.994 0.006
E72.0 Disorders of amino-acid transport
0.000 0.994 0.006
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.994 0.006
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.994 0.006
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.994 0.006
E76.2 Other mucopolysaccharidoses
0.000 0.994 0.006
E76.1 Mucopolysaccharidosis, type II
0.000 0.994 0.006
E76.0 Mucopolysaccharidosis, type I
0.000 0.994 0.006
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.994 0.006
E77.8 Other disorders of glycoprotein metabolism
0.000 0.994 0.006
E77.1 Defects in glycoprotein degradation
0.000 0.994 0.006
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.994 0.006
E84.9 Cystic fibrosis, unspecified
0.000 0.994 0.006
E84.8 Cystic fibrosis with other manifestations
0.000 0.994 0.006
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.994 0.006
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.994 0.006
S20.8 Superficial injuries of other and unspecified parts of thorax
0.006 0.994 0.000
E88.9 Metabolic disorder, unspecified
0.000 0.994 0.006
E88.3 Tumour lysis syndrome
0.000 0.994 0.006
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.994 0.006
M25.57 Pain in joint (Ankle and foot)
0.000 0.994 0.006
E88.8 Other specified metabolic disorders
0.000 0.994 0.006
S20.2 Contusion of thorax
0.006 0.994 0.000
H65-H75 Diseases of middle ear and mastoid
0.000 0.994 0.006
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.994 0.006
E75.6 Lipid storage disorder, unspecified
0.000 0.994 0.005
E75.5 Other lipid storage disorders
0.000 0.994 0.005
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.994 0.005
E75.3 Sphingolipidosis, unspecified
0.000 0.994 0.005
E75.1 Other gangliosidosis
0.000 0.994 0.005
E75.0 GM2 gangliosidosis
0.000 0.994 0.005
E88.2 Lipomatosis, not elsewhere classified
0.000 0.995 0.005
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.995 0.005
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.995 0.005
E70.2 Disorders of tyrosine metabolism
0.000 0.995 0.005
E70.1 Other hyperphenylalaninaemias
0.000 0.995 0.005
E70.0 Classical phenylketonuria
0.000 0.995 0.005
H70.9 Mastoiditis, unspecified
0.000 0.995 0.005
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.995 0.005
H70 Mastoiditis and related conditions
0.000 0.995 0.005
H72.1 Attic perforation of tympanic membrane
0.000 0.995 0.005
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.995 0.005
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.000 0.995 0.005
I12.9 Hypertensive renal disease without renal failure
0.001 0.995 0.005
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.995 0.005
H72.8 Other perforations of tympanic membrane
0.000 0.995 0.005
I68.0 Cerebral amyloid angiopathy
0.000 0.995 0.005
H66 Suppurative and unspecified otitis media
0.000 0.995 0.005
E75.2 Other sphingolipidosis
0.000 0.995 0.005
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.995 0.005
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.995 0.005
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.995 0.005
S20 Superficial injury of thorax
0.005 0.995 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.995 0.005
H72.2 Other marginal perforations of tympanic membrane
0.000 0.995 0.005
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.000 0.995 0.005
E80.2 Other porphyria
0.000 0.995 0.005
H74.2 Discontinuity and dislocation of ear ossicles
0.000 0.995 0.005
H72.9 Perforation of tympanic membrane, unspecified
0.000 0.995 0.005
H74.4 Polyp of middle ear
0.000 0.995 0.005
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.995 0.005
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.995 0.004
E80.5 Crigler-Najjar syndrome
0.000 0.995 0.004
E80.3 Defects of catalase and peroxydase
0.000 0.995 0.004
E80.0 Hereditary erythropoietic porphyria
0.000 0.995 0.004
E70.3 Albinism
0.000 0.995 0.004
E86 Volume depletion
0.000 0.995 0.005
H73 Other disorders of tympanic membrane
0.000 0.995 0.004
H71 Cholesteatoma of middle ear
0.000 0.995 0.005
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.996 0.004
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.996 0.004
H68 Eustachian salpingitis and obstruction
0.000 0.996 0.004
H67 Otitis media in diseases classified elsewhere
0.000 0.996 0.004
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.996 0.004
I83 Varicose veins of lower extremities
0.000 0.996 0.004
E80.4 Gilbert's syndrome
0.000 0.996 0.004
I08.0 Disorders of both mitral and aortic valves
0.001 0.996 0.004
K42.9 Umbilical hernia without obstruction or gangrene
0.000 0.996 0.004
H74.1 Adhesive middle ear disease
0.000 0.996 0.004
E80.1 Porphyria cutanea tarda
0.000 0.996 0.004
I62 Other nontraumatic intracranial haemorrhage
0.000 0.996 0.004
H66.9 Otitis media, unspecified
0.000 0.996 0.004
H66.4 Suppurative otitis media, unspecified
0.000 0.996 0.004
H70.2 Petrositis
0.000 0.996 0.004
H70.0 Acute mastoiditis
0.000 0.996 0.004
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.996 0.004
H66.1 Chronic tubotympanic suppurative otitis media
0.000 0.996 0.004
H73.8 Other specified disorders of tympanic membrane
0.000 0.996 0.004
H70.1 Chronic mastoiditis
0.000 0.996 0.004
H66.2 Chronic atticoantral suppurative otitis media
0.000 0.996 0.004
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.996 0.004
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.996 0.003
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.996 0.003
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.996 0.003
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.996 0.003
H66.3 Other chronic suppurative otitis media
0.000 0.996 0.004
C67.5 Bladder neck
0.004 0.996 0.000
K08 Other disorders of teeth and supporting structures
0.000 0.996 0.004
H70.8 Other mastoiditis and related conditions
0.000 0.996 0.004
K08.8 Other specified disorders of teeth and supporting structures
0.000 0.996 0.004
S20.7 Multiple superficial injuries of thorax
0.004 0.996 0.000
H74.0 Tympanosclerosis
0.000 0.996 0.004
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.996 0.004
I65.1 Occlusion and stenosis of basilar artery
0.000 0.996 0.004
I87 Other disorders of veins
0.000 0.996 0.004
I81 Portal vein thrombosis
0.000 0.996 0.004
E80.6 Other disorders of bilirubin metabolism
0.000 0.996 0.003
S20.1 Other and unspecified superficial injuries of breast
0.004 0.996 0.000
H66.0 Acute suppurative otitis media
0.000 0.996 0.004
I87.1 Compression of vein
0.000 0.996 0.004
O00.1 Tubal pregnancy
0.004 0.996 0.000
S20.4 Other superficial injuries of back wall of thorax
0.003 0.996 0.000
S20.0 Contusion of breast
0.003 0.996 0.000
E11.5 With peripheral circulatory complications
0.000 0.996 0.004
H73.1 Chronic myringitis
0.000 0.996 0.003
H73.0 Acute myringitis
0.000 0.996 0.003
S20.3 Other superficial injuries of front wall of thorax
0.003 0.996 0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.001 0.997 0.003
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.000 0.997 0.003
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.000 0.997 0.003
I88 Nonspecific lymphadenitis
0.000 0.997 0.003
H67.8 Otitis media in other diseases classified elsewhere
0.000 0.997 0.003
H67.1 Otitis media in viral diseases classified elsewhere
0.000 0.997 0.003
H67.0 Otitis media in bacterial diseases classified elsewhere
0.000 0.997 0.003
H68.1 Obstruction of Eustachian tube
0.000 0.997 0.003
H68.0 Eustachian salpingitis
0.000 0.997 0.003
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.997 0.003
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere
0.000 0.997 0.003
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.997 0.003
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.003 0.997 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.997 0.003
I66.0 Occlusion and stenosis of middle cerebral artery
0.001 0.997 0.003
C67.1 Dome of bladder
0.003 0.997 0.000
I62.1 Nontraumatic extradural haemorrhage
0.000 0.997 0.003
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.997 0.003
Z13.6 Special screening examination for cardiovascular disorders
0.003 0.997 0.000
H69 Other disorders of Eustachian tube
0.000 0.997 0.003
H73.9 Disorder of tympanic membrane, unspecified
0.000 0.997 0.003
E11.9 Without complications
0.000 0.997 0.003
C67 Malignant neoplasm of bladder
0.003 0.997 0.000
R50.9 Fever, unspecified
0.003 0.997 0.000
I65.2 Occlusion and stenosis of carotid artery
0.000 0.997 0.003
K08.0 Exfoliation of teeth due to systemic causes
0.000 0.997 0.003
G97.8 Other postprocedural disorders of nervous system
0.000 0.997 0.003
J36 Peritonsillar abscess
0.003 0.997 0.000
I87.9 Disorder of vein, unspecified
0.000 0.997 0.003
I87.0 Postphlebitic syndrome
0.000 0.997 0.003
I08.1 Disorders of both mitral and tricuspid valves
0.001 0.997 0.002
C67.2 Lateral wall of bladder
0.003 0.997 0.000
C83.3 Large cell (diffuse)
0.003 0.997 0.000
C18.9 Colon, unspecified
0.000 0.997 0.003
G97.1 Other reaction to spinal and lumbar puncture
0.000 0.997 0.003
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.997 0.003
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.000 0.997 0.003
O03.4 Incomplete, without complication
0.000 0.997 0.003
C81.1 Nodular sclerosis
0.003 0.997 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.997 0.002
I87.8 Other specified disorders of veins
0.000 0.997 0.003
I88.8 Other nonspecific lymphadenitis
0.000 0.997 0.002
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.997 0.002
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.997 0.002
E89.5 Postprocedural testicular hypofunction
0.000 0.997 0.002
E89.1 Postprocedural hypoinsulinaemia
0.000 0.997 0.002
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.997 0.002
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.003 0.997 0.000
I85 Oesophageal varices
0.000 0.997 0.003
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.997 0.003
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.000 0.997 0.003
G97.0 Cerebrospinal fluid leak from spinal puncture
0.000 0.997 0.003
K08.2 Atrophy of edentulous alveolar ridge
0.000 0.997 0.002
H69.0 Patulous Eustachian tube
0.000 0.997 0.002
K65.0 Acute peritonitis
0.003 0.997 0.000
C67.8 Overlapping lesion of bladder
0.002 0.997 0.000
C67.7 Urachus
0.002 0.997 0.000
C67.4 Posterior wall of bladder
0.002 0.997 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.997 0.002
O14.9 Preeclampsia, unspecified
0.002 0.997 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.998 0.002
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.998 0.002
C67.6 Ureteric orifice
0.002 0.998 0.000
C67.0 Trigone of bladder
0.002 0.998 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.000 0.998 0.002
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.998 0.002
C67.3 Anterior wall of bladder
0.002 0.998 0.000
E89.4 Postprocedural ovarian failure
0.000 0.998 0.002
H05.2 Exophthalmic conditions
0.002 0.998 0.000
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.998 0.002
A04.8 Other specified bacterial intestinal infections
0.000 0.998 0.002
E11 Non-insulin-dependent diabetes mellitus
0.000 0.998 0.002
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.000 0.998 0.002
C83 Diffuse non-Hodgkin's lymphoma
0.002 0.998 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.000 0.998 0.002
H69.8 Other specified disorders of Eustachian tube
0.000 0.998 0.002
L43.9 Lichen planus, unspecified
0.002 0.998 0.000
C81 Hodgkin's disease
0.002 0.998 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.998 0.002
E11.1 With ketoacidosis
0.000 0.998 0.002
N85.1 Endometrial adenomatous hyperplasia
0.002 0.998 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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