TreeWAS – Variant ID: rs2964898

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.027	0.973	0.000
O36 Maternal care for other known or suspected foetal problems	0.026	0.974	0.000
O60-O75 Complications of labour and delivery	0.025	0.975	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.024	0.976	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.024	0.976	0.000
O36.5 Maternal care for poor foetal growth	0.023	0.977	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.023	0.977	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.023	0.977	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.023	0.977	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.023	0.977	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.022	0.978	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.978	0.022
O20 Haemorrhage in early pregnancy	0.022	0.978	0.000
O70 Perineal laceration during delivery	0.022	0.978	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.978	0.022
T43.2 Other and unspecified antidepressants	0.000	0.978	0.022
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.978	0.022
T39.1 4-Aminophenol derivatives	0.000	0.978	0.022
O41 Other disorders of amniotic fluid and membranes	0.021	0.978	0.000
O43 Placental disorders	0.021	0.979	0.000
O70.2 Third degree perineal laceration during delivery	0.021	0.979	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.979	0.021
O40 Polyhydramnios	0.021	0.979	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.021	0.979	0.000
O30 Multiple gestation	0.021	0.979	0.000
O47 False labour	0.020	0.979	0.000
O44 Placenta praevia	0.020	0.980	0.000
O71 Other obstetric trauma	0.020	0.980	0.000
T42.4 Benzodiazepines	0.000	0.980	0.020
O36.9 Maternal care for foetal problem, unspecified	0.020	0.980	0.000
O36.8 Maternal care for other specified foetal problems	0.020	0.980	0.000
O45 Premature separation of placenta [abruptio placentae]	0.019	0.980	0.000
O33 Maternal care for known or suspected disproportion	0.019	0.980	0.000
O31 Complications specific to multiple gestation	0.019	0.980	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.019	0.981	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.019	0.981	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.981	0.019
O48 Prolonged pregnancy	0.019	0.981	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.019	0.981	0.000
O70.1 Second degree perineal laceration during delivery	0.019	0.981	0.000
O63 Long labour	0.019	0.981	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.019	0.981	0.000
O36.6 Maternal care for excessive foetal growth	0.019	0.981	0.000
O36.4 Maternal care for intra-uterine death	0.019	0.981	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.019	0.981	0.000
O36.2 Maternal care for hydrops foetalis	0.019	0.981	0.000
O36.1 Maternal care for other isoimmunisation	0.019	0.981	0.000
O66 Other obstructed labour	0.019	0.981	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.019	0.981	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.018	0.981	0.000
O72 Postpartum haemorrhage	0.018	0.982	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.018	0.982	0.000
O74 Complications of anaesthesia during labour and delivery	0.018	0.982	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.018	0.982	0.000
O61 Failed induction of labour	0.018	0.982	0.000
O60 Preterm delivery	0.018	0.982	0.000
O20.8 Other haemorrhage in early pregnancy	0.018	0.982	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.982	0.018
O34 Maternal care for known or suspected abnormality of pelvic organs	0.018	0.982	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.018	0.982	0.000
O73 Retained placenta and membranes, without haemorrhage	0.018	0.982	0.000
O75.0 Maternal distress during labour and delivery	0.018	0.982	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.982	0.018
O85-O92 Complications predominantly related to the puerperium	0.017	0.983	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.017	0.983	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.017	0.983	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.017	0.983	0.000
O43.1 Malformation of placenta	0.017	0.983	0.000
O24 Diabetes mellitus in pregnancy	0.017	0.983	0.000
O32.1 Maternal care for breech presentation	0.017	0.983	0.000
O71.8 Other specified obstetric trauma	0.017	0.983	0.000
O41.0 Oligohydramnios	0.017	0.983	0.000
O63.0 Prolonged first stage (of labour)	0.017	0.983	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.017	0.983	0.000
O62 Abnormalities of forces of labour	0.017	0.983	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.983	0.017
O41.8 Other specified disorders of amniotic fluid and membranes	0.016	0.983	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.983	0.016
O32.9 Maternal care for malpresentation of foetus, unspecified	0.016	0.983	0.000
O32.8 Maternal care for other malpresentation of foetus	0.016	0.983	0.000
O32.6 Maternal care for compound presentation	0.016	0.983	0.000
O32.4 Maternal care for high head at term	0.016	0.983	0.000
O32.3 Maternal care for face, brow and chin presentation	0.016	0.983	0.000
O32.2 Maternal care for transverse and oblique lie	0.016	0.983	0.000
O32.0 Maternal care for unstable lie	0.016	0.983	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.983	0.016
O29 Complications of anaesthesia during pregnancy	0.016	0.983	0.000
O28 Abnormal findings on antenatal screening of mother	0.016	0.983	0.000
O22 Venous complications in pregnancy	0.016	0.983	0.000
O21 Excessive vomiting in pregnancy	0.016	0.983	0.000
O25 Malnutrition in pregnancy	0.016	0.983	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.016	0.983	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.016	0.983	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.016	0.983	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.016	0.983	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.016	0.983	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.016	0.983	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.016	0.983	0.000
O42 Premature rupture of membranes	0.016	0.984	0.000
O75.9 Complication of labour and delivery, unspecified	0.016	0.984	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.016	0.984	0.000
O75.4 Other complications of obstetric surgery and procedures	0.016	0.984	0.000
O75.3 Other infection during labour	0.016	0.984	0.000
O75.1 Shock during or following labour and delivery	0.016	0.984	0.000
O30.0 Twin pregnancy	0.016	0.984	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.984	0.016
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.984	0.016
T43.6 Psychostimulants with abuse potential	0.000	0.984	0.016
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.984	0.016
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.984	0.016
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.984	0.016
O75.8 Other specified complications of labour and delivery	0.016	0.984	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.016	0.984	0.000
O70.9 Perineal laceration during delivery, unspecified	0.016	0.984	0.000
O70.3 Fourth degree perineal laceration during delivery	0.016	0.984	0.000
O23 Infections of genito-urinary tract in pregnancy	0.016	0.984	0.000
O00-O08 Pregnancy with abortive outcome	0.016	0.984	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.984	0.016
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.984	0.016
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.984	0.016
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.984	0.016
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.984	0.016
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.984	0.016
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.984	0.016
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.984	0.016
T36 Poisoning by systemic antibiotics	0.000	0.984	0.016
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.016	0.984	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.984	0.016
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.984	0.016
T39.4 Antirheumatics, not elsewhere classified	0.000	0.984	0.016
T39.2 Pyrazolone derivatives	0.000	0.984	0.016
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.016	0.984	0.000
O41.1 Infection of amniotic sac and membranes	0.016	0.984	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.016	0.984	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.015	0.984	0.000
O44.1 Placenta praevia with haemorrhage	0.015	0.984	0.000
O43.9 Placental disorder, unspecified	0.015	0.984	0.000
O43.8 Other placental disorders	0.015	0.984	0.000
O43.2 Morbidly adherent placenta	0.015	0.984	0.000
O43.0 Placental transfusion syndromes	0.015	0.984	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.015	0.984	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.015	0.985	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.015	0.985	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.985	0.015
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.985	0.015
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.985	0.015
T42.3 Barbiturates	0.000	0.985	0.015
T42.2 Succinimides and oxazolidinediones	0.000	0.985	0.015
T42.1 Iminostilbenes	0.000	0.985	0.015
T42.0 Hydantoin derivatives	0.000	0.985	0.015
O94-O99 Other obstetric conditions, not elsewhere classified	0.015	0.985	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.015	0.985	0.000
O30.9 Multiple gestation, unspecified	0.015	0.985	0.000
O30.8 Other multiple gestation	0.015	0.985	0.000
O30.2 Quadruplet pregnancy	0.015	0.985	0.000
O30.1 Triplet pregnancy	0.015	0.985	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.015	0.985	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.985	0.015
O72.0 Third-stage haemorrhage	0.015	0.985	0.000
O47.9 False labour, unspecified	0.015	0.985	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.015	0.985	0.000
O71.9 Obstetric trauma, unspecified	0.015	0.985	0.000
O71.7 Obstetric haematoma of pelvis	0.015	0.985	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.015	0.985	0.000
O71.5 Other obstetric injury to pelvic organs	0.015	0.985	0.000
O71.4 Obstetric high vaginal laceration alone	0.015	0.985	0.000
O71.3 Obstetric laceration of cervix	0.015	0.985	0.000
O71.2 Postpartum inversion of uterus	0.015	0.985	0.000
O71.1 Rupture of uterus during labour	0.015	0.985	0.000
O71.0 Rupture of uterus before onset of labour	0.015	0.985	0.000
T39.0 Salicylates	0.000	0.985	0.015
T40.2 Other opioids	0.000	0.986	0.014
O31.8 Other complications specific to multiple gestation	0.014	0.986	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.014	0.986	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.014	0.986	0.000
O31.0 Papyraceous foetus	0.014	0.986	0.000
O33.9 Maternal care for disproportion, unspecified	0.014	0.986	0.000
O33.8 Maternal care for disproportion of other origin	0.014	0.986	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.014	0.986	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.014	0.986	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.014	0.986	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.014	0.986	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.014	0.986	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.014	0.986	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.014	0.986	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.014	0.986	0.000
O45.9 Premature separation of placenta, unspecified	0.014	0.986	0.000
O45.8 Other premature separation of placenta	0.014	0.986	0.000
O45.0 Premature separation of placenta with coagulation defect	0.014	0.986	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.014	0.986	0.000
O67.8 Other intrapartum haemorrhage	0.014	0.986	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.014	0.986	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.014	0.986	0.000
O63.9 Long labour, unspecified	0.014	0.986	0.000
O66.9 Obstructed labour, unspecified	0.013	0.986	0.000
O66.8 Other specified obstructed labour	0.013	0.986	0.000
O66.4 Failed trial of labour, unspecified	0.013	0.986	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.013	0.986	0.000
O66.2 Obstructed labour due to unusually large foetus	0.013	0.986	0.000
O66.1 Obstructed labour due to locked twins	0.013	0.986	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.013	0.986	0.000
O34.1 Maternal care for tumour of corpus uteri	0.013	0.986	0.000
O46.8 Other antepartum haemorrhage	0.013	0.986	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.013	0.986	0.000
O20.0 Threatened abortion	0.013	0.986	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.013	0.986	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.013	0.986	0.000
O72.3 Postpartum coagulation defects	0.013	0.987	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.013	0.987	0.000
O60.3 Preterm delivery without spontaneous labour	0.013	0.987	0.000
O60.2 Preterm spontaneous labour with term delivery	0.013	0.987	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.013	0.987	0.000
O60.0 Preterm labour without delivery	0.013	0.987	0.000
O61.9 Failed induction of labour, unspecified	0.013	0.987	0.000
O61.8 Other failed induction of labour	0.013	0.987	0.000
O61.1 Failed instrumental induction of labour	0.013	0.987	0.000
O61.0 Failed medical induction of labour	0.013	0.987	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.013	0.987	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.013	0.987	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.013	0.987	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.013	0.987	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.013	0.987	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.013	0.987	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.013	0.987	0.000
O65.0 Obstructed labour due to deformed pelvis	0.013	0.987	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.013	0.987	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.013	0.987	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.013	0.987	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.013	0.987	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.013	0.987	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.013	0.987	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.013	0.987	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.013	0.987	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.013	0.987	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.013	0.987	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.987	0.013
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.013	0.987	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.013	0.987	0.000
O34.6 Maternal care for abnormality of vagina	0.013	0.987	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.013	0.987	0.000
O34.4 Maternal care for other abnormalities of cervix	0.013	0.987	0.000
O34.3 Maternal care for cervical incompetence	0.013	0.987	0.000
O34.0 Maternal care for congenital malformation of uterus	0.013	0.987	0.000
O00 Ectopic pregnancy	0.013	0.987	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.013	0.987	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.987	0.013
T40.8 Lysergide [LSD]	0.000	0.987	0.013
T40.7 Cannabis (derivatives)	0.000	0.987	0.013
T40.6 Other and unspecified narcotics	0.000	0.987	0.013
T40.5 Cocaine	0.000	0.987	0.013
T40.4 Other synthetic narcotics	0.000	0.987	0.013
T40.3 Methadone	0.000	0.987	0.013
T40.1 Heroin	0.000	0.987	0.013
T40.0 Opium	0.000	0.987	0.013
O47.0 False labour before 37 completed weeks of gestation	0.013	0.987	0.000
O64.1 Obstructed labour due to breech presentation	0.013	0.987	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.013	0.987	0.000
O91 Infections of breast associated with childbirth	0.013	0.987	0.000
O90 Complications of the puerperium, not elsewhere classified	0.013	0.987	0.000
O89 Complications of anaesthesia during the puerperium	0.013	0.987	0.000
O88 Obstetric embolism	0.013	0.987	0.000
O87 Venous complications in the puerperium	0.013	0.987	0.000
O86 Other puerperal infections	0.013	0.987	0.000
O85 Puerperal sepsis	0.013	0.987	0.000
O80-O84 Delivery	0.013	0.987	0.000
O46.9 Antepartum haemorrhage, unspecified	0.013	0.987	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.012	0.987	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.012	0.987	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.012	0.987	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.012	0.987	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.012	0.987	0.000
O73.0 Retained placenta, without haemorrhage	0.012	0.987	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.012	0.987	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.012	0.988	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.012	0.988	0.000
O64.5 Obstructed labour due to compound presentation	0.012	0.988	0.000
O64.4 Obstructed labour due to shoulder presentation	0.012	0.988	0.000
O64.3 Obstructed labour due to brow presentation	0.012	0.988	0.000
O64.2 Obstructed labour due to face presentation	0.012	0.988	0.000
O72.1 Other immediate postpartum haemorrhage	0.012	0.988	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.012	0.988	0.000
O62.9 Abnormality of forces of labour, unspecified	0.012	0.988	0.000
O62.8 Other abnormalities of forces of labour	0.012	0.988	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.012	0.988	0.000
O62.3 Precipitate labour	0.012	0.988	0.000
O62.1 Secondary uterine inertia	0.012	0.988	0.000
O62.0 Primary inadequate contractions	0.012	0.988	0.000
T50.8 Diagnostic agents	0.000	0.988	0.012
T50.7 Analeptics and opioid receptor antagonists	0.000	0.988	0.012
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.988	0.012
T50.5 Appetite depressants	0.000	0.988	0.012
T50.4 Drugs affecting uric acid metabolism	0.000	0.988	0.012
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.988	0.012
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.988	0.012
T50.1 Loop [high-ceiling] diuretics	0.000	0.988	0.012
T50.0 Mineralocorticoids and their antagonists	0.000	0.988	0.012
O21.9 Vomiting of pregnancy, unspecified	0.012	0.988	0.000
O21.8 Other vomiting complicating pregnancy	0.012	0.988	0.000
O21.2 Late vomiting of pregnancy	0.012	0.988	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.012	0.988	0.000
O21.0 Mild hyperemesis gravidarum	0.012	0.988	0.000
O22.9 Venous complication in pregnancy, unspecified	0.012	0.988	0.000
O22.8 Other venous complications in pregnancy	0.012	0.988	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.012	0.988	0.000
O22.4 Haemorrhoids in pregnancy	0.012	0.988	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.012	0.988	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.012	0.988	0.000
O22.1 Genital varices in pregnancy	0.012	0.988	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.012	0.988	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.012	0.988	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.012	0.988	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.012	0.988	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.012	0.988	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.012	0.988	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.012	0.988	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.012	0.988	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.012	0.988	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.012	0.988	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.012	0.988	0.000
O29.6 Failed or difficult intubation during pregnancy	0.012	0.988	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.012	0.988	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.012	0.988	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.012	0.988	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.012	0.988	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.012	0.988	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.012	0.988	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.012	0.988	0.000
O03 Spontaneous abortion	0.012	0.988	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.012	0.988	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.012	0.988	0.000
O23.5 Infections of the genital tract in pregnancy	0.012	0.988	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.012	0.988	0.000
O23.2 Infections of urethra in pregnancy	0.012	0.988	0.000
O23.1 Infections of bladder in pregnancy	0.012	0.988	0.000
O23.0 Infections of kidney in pregnancy	0.012	0.988	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.012	0.988	0.000
O07 Failed attempted abortion	0.012	0.988	0.000
O06 Unspecified abortion	0.012	0.988	0.000
O05 Other abortion	0.012	0.988	0.000
O01 Hydatidiform mole	0.012	0.988	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.988	0.012
T36.8 Other systemic antibiotics	0.000	0.988	0.012
T36.7 Antifungal antibiotics, systemically used	0.000	0.988	0.012
T36.6 Rifamycins	0.000	0.988	0.012
T36.5 Aminoglycosides	0.000	0.988	0.012
T36.4 Tetracyclines	0.000	0.988	0.012
T36.3 Macrolides	0.000	0.988	0.012
T36.2 Chloramphenicol group	0.000	0.988	0.012
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.988	0.012
T36.0 Penicillins	0.000	0.988	0.012
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.988	0.012
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.988	0.012
T37.5 Antiviral drugs	0.000	0.988	0.012
T37.4 Anthelminthics	0.000	0.988	0.012
T37.3 Other antiprotozoal drugs	0.000	0.988	0.012
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.988	0.012
T37.1 Antimycobacterial drugs	0.000	0.988	0.012
T37.0 Sulphonamides	0.000	0.988	0.012
T41.5 Therapeutic gases	0.000	0.988	0.012
T41.4 Anaesthetic, unspecified	0.000	0.988	0.012
T41.3 Local anaesthetics	0.000	0.988	0.012
T41.2 Other and unspecified general anaesthetics	0.000	0.988	0.012
T41.1 Intravenous anaesthetics	0.000	0.988	0.012
T41.0 Inhaled anaesthetics	0.000	0.988	0.012
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.988	0.012
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.988	0.012
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.988	0.012
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.988	0.012
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.988	0.012
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.988	0.012
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.988	0.012
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.988	0.012
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.988	0.012
T44.0 Anticholinesterase agents	0.000	0.988	0.012
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.988	0.012
T45.8 Other primarily systemic and haematological agents	0.000	0.988	0.012
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.988	0.012
T45.6 Fibrinolysis-affecting drugs	0.000	0.988	0.012
T45.5 Anticoagulants	0.000	0.988	0.012
T45.4 Iron and its compounds	0.000	0.988	0.012
T45.3 Enzymes, not elsewhere classified	0.000	0.988	0.012
T45.2 Vitamins, not elsewhere classified	0.000	0.988	0.012
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.988	0.012
T45.0 Antiallergic and antiemetic drugs	0.000	0.988	0.012
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.988	0.012
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.988	0.012
T46.7 Peripheral vasodilators	0.000	0.988	0.012
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.988	0.012
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.988	0.012
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.988	0.012
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.988	0.012
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.988	0.012
T46.1 Calcium-channel blockers	0.000	0.988	0.012
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.988	0.012
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.988	0.012
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.988	0.012
T47.7 Emetics	0.000	0.988	0.012
T47.6 Antidiarrhoeal drugs	0.000	0.988	0.012
T47.5 Digestants	0.000	0.988	0.012
T47.4 Other laxatives	0.000	0.988	0.012
T47.3 Saline and osmotic laxatives	0.000	0.988	0.012
T47.2 Stimulant laxatives	0.000	0.988	0.012
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.988	0.012
T47.0 Histamine H(2)-receptor antagonists	0.000	0.988	0.012
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.988	0.012
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.988	0.012
T48.5 Anti-common-cold drugs	0.000	0.988	0.012
T48.4 Expectorants	0.000	0.988	0.012
T48.3 Antitussives	0.000	0.988	0.012
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.988	0.012
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.988	0.012
T48.0 Oxytocic drugs	0.000	0.988	0.012
T49.9 Topical agent, unspecified	0.000	0.988	0.012
T49.8 Other topical agents	0.000	0.988	0.012
T49.7 Dental drugs, topically applied	0.000	0.988	0.012
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.988	0.012
T49.5 Ophthalmological drugs and preparations	0.000	0.988	0.012
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.988	0.012
T49.3 Emollients, demulcents and protectants	0.000	0.988	0.012
T49.2 Local astringents and local detergents	0.000	0.988	0.012
T49.1 Antipruritics	0.000	0.988	0.012
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.988	0.012
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.012	0.988	0.000
O15 Eclampsia	0.011	0.988	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.011	0.988	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.011	0.988	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.011	0.988	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.011	0.988	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O26.5 Maternal hypotension syndrome	0.011	0.989	0.000
O26.4 Herpes gestationis	0.011	0.989	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.011	0.989	0.000
O26.2 Pregnancy care of habitual aborter	0.011	0.989	0.000
O26.1 Low weight gain in pregnancy	0.011	0.989	0.000
O26.0 Excessive weight gain in pregnancy	0.011	0.989	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O97 Death from sequelae of direct obstetric causes	0.011	0.989	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.011	0.989	0.000
O95 Obstetric death of unspecified cause	0.011	0.989	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O62.2 Other uterine inertia	0.011	0.989	0.000
O26.9 Pregnancy-related condition, unspecified	0.011	0.989	0.000
O42.9 Premature rupture of membranes, unspecified	0.011	0.989	0.000
O04 Medical abortion	0.011	0.989	0.000
O63.1 Prolonged second stage (of labour)	0.011	0.989	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.989	0.011
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.989	0.011
T38.7 Androgens and anabolic congeners	0.000	0.989	0.011
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.989	0.011
T38.5 Other oestrogens and progestogens	0.000	0.989	0.011
T38.4 Oral contraceptives	0.000	0.989	0.011
T38.2 Antithyroid drugs	0.000	0.989	0.011
T38.1 Thyroid hormones and substitutes	0.000	0.989	0.011
T38.0 Glucocorticoids and synthetic analogues	0.000	0.989	0.011
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.011	0.989	0.000
O00.1 Tubal pregnancy	0.011	0.989	0.000
O16 Unspecified maternal hypertension	0.010	0.989	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.010	0.990	0.000
O14.9 Preeclampsia, unspecified	0.010	0.990	0.000
O26.8 Other specified pregnancy-related conditions	0.010	0.990	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.010	0.990	0.000
O69.8 Labour and delivery complicated by other cord complications	0.010	0.990	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.010	0.990	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.010	0.990	0.000
O69.3 Labour and delivery complicated by short cord	0.010	0.990	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.010	0.990	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.990	0.010
O00.9 Ectopic pregnancy, unspecified	0.009	0.990	0.000
O00.8 Other ectopic pregnancy	0.009	0.990	0.000
O00.2 Ovarian pregnancy	0.009	0.990	0.000
O00.0 Abdominal pregnancy	0.009	0.990	0.000
O86.8 Other specified puerperal infections	0.009	0.991	0.000
O86.4 Pyrexia of unknown origin following delivery	0.009	0.991	0.000
O86.3 Other genito-urinary tract infections following delivery	0.009	0.991	0.000
O86.2 Urinary tract infection following delivery	0.009	0.991	0.000
O86.1 Other infection of genital tract following delivery	0.009	0.991	0.000
O86.0 Infection of obstetric surgical wound	0.009	0.991	0.000
O87.9 Venous complication in the puerperium, unspecified	0.009	0.991	0.000
O87.8 Other venous complications in the puerperium	0.009	0.991	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.009	0.991	0.000
O87.2 Haemorrhoids in the puerperium	0.009	0.991	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.009	0.991	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.009	0.991	0.000
O88.8 Other obstetric embolism	0.009	0.991	0.000
O88.3 Obstetric pyaemic and septic embolism	0.009	0.991	0.000
O88.2 Obstetric blood-clot embolism	0.009	0.991	0.000
O88.1 Amniotic fluid embolism	0.009	0.991	0.000
O88.0 Obstetric air embolism	0.009	0.991	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.009	0.991	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.009	0.991	0.000
O89.6 Failed or difficult intubation during the puerperium	0.009	0.991	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.009	0.991	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.009	0.991	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.009	0.991	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.009	0.991	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.009	0.991	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.009	0.991	0.000
O90.9 Complication of the puerperium, unspecified	0.009	0.991	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.009	0.991	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations