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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2965324
log Bayes Factor = 13.1575
Chromosome 15   position 48,274,460  (GRCh37) Explore rs2965324 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N18 Chronic renal failure
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.995 0.005 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.995 0.005 0.000
E70-E90 Metabolic disorders
0.993 0.007 0.000
N17 Acute renal failure
0.992 0.008 0.000
N18.3 Chronic kidney disease, stage 3
0.989 0.011 0.000
N17.9 Acute renal failure, unspecified
0.987 0.013 0.000
Chapter VII Diseases of the eye and adnexa
0.986 0.014 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.983 0.017 0.000
E20-E35 Disorders of other endocrine glands
0.981 0.019 0.000
E87.5 Hyperkalaemia
0.978 0.022 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.977 0.023 0.000
H90-H95 Other disorders of ear
0.977 0.023 0.000
Chapter XX External causes of morbidity and mortality
0.973 0.027 0.000
S60-S69 Injuries to the wrist and hand
0.971 0.029 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.970 0.030 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.958 0.042 0.000
H65-H75 Diseases of middle ear and mastoid
0.953 0.047 0.000
S62 Fracture at wrist and hand level
0.947 0.053 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.946 0.054 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.940 0.060 0.000
N00-N08 Glomerular diseases
0.938 0.062 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.936 0.064 0.000
N18.9 Chronic renal failure, unspecified
0.933 0.067 0.000
H60-H62 Diseases of external ear
0.929 0.071 0.000
S00-S09 Injuries to the head
0.929 0.071 0.000
T43.2 Other and unspecified antidepressants
0.921 0.079 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.916 0.084 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.916 0.084 0.000
H43-H45 Disorders of vitreous body and globe
0.915 0.085 0.000
H72 Perforation of tympanic membrane
0.915 0.085 0.000
T90 Sequelae of injuries of head
0.912 0.088 0.000
O60-O75 Complications of labour and delivery
0.906 0.094 0.000
S01 Open wound of head
0.904 0.096 0.000
O32.1 Maternal care for breech presentation
0.904 0.096 0.000
S62.6 Fracture of other finger
0.902 0.098 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.898 0.102 0.000
N18.4 Chronic kidney disease, stage 4
0.896 0.104 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.895 0.105 0.000
N18.5 Chronic kidney disease, stage 5
0.892 0.108 0.000
H90 Conductive and sensorineural hearing loss
0.888 0.112 0.000
H91 Other hearing loss
0.887 0.113 0.000
S80-S89 Injuries to the knee and lower leg
0.886 0.114 0.000
E87.7 Fluid overload
0.882 0.118 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.878 0.122 0.000
N73 Other female pelvic inflammatory diseases
0.876 0.124 0.000
N18.0 End-stage renal disease
0.872 0.128 0.000
E86 Volume depletion
0.866 0.134 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.866 0.134 0.000
H25-H28 Disorders of lens
0.864 0.136 0.000
S01.0 Open wound of scalp
0.863 0.137 0.000
N25-N29 Other disorders of kidney and ureter
0.861 0.139 0.000
E21.0 Primary hyperparathyroidism
0.852 0.148 0.000
O42 Premature rupture of membranes
0.847 0.153 0.000
O47 False labour
0.847 0.153 0.000
T93 Sequelae of injuries of lower limb
0.846 0.154 0.000
O48 Prolonged pregnancy
0.846 0.154 0.000
S62.60 Fracture of other finger (closed)
0.846 0.154 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.845 0.155 0.000
O00-O08 Pregnancy with abortive outcome
0.843 0.157 0.000
S68 Traumatic amputation of wrist and hand
0.842 0.158 0.000
H60 Otitis externa
0.840 0.160 0.000
H43 Disorders of vitreous body
0.837 0.163 0.000
E21.3 Hyperparathyroidism, unspecified
0.836 0.164 0.000
H10-H13 Disorders of conjunctiva
0.834 0.166 0.000
T66-T78 Other and unspecified effects of external causes
0.833 0.167 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.832 0.168 0.000
H26 Other cataract
0.830 0.170 0.000
N02 Recurrent and persistent haematuria
0.827 0.173 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.827 0.173 0.000
W00-W19 Falls
0.826 0.174 0.000
O41 Other disorders of amniotic fluid and membranes
0.825 0.175 0.000
H91.9 Hearing loss, unspecified
0.823 0.177 0.000
O16 Unspecified maternal hypertension
0.822 0.178 0.000
T42.4 Benzodiazepines
0.821 0.179 0.000
S62.5 Fracture of thumb
0.821 0.179 0.000
Chapter IX Diseases of the circulatory system
0.821 0.179 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.819 0.181 0.000
H50 Other strabismus
0.817 0.183 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.813 0.187 0.000
E23 Hypofunction and other disorders of pituitary gland
0.813 0.187 0.000
N73.6 Female pelvic peritoneal adhesions
0.812 0.188 0.000
H30-H36 Disorders of choroid and retina
0.811 0.189 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.811 0.189 0.000
N71 Inflammatory disease of uterus, except cervix
0.811 0.189 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.807 0.193 0.000
E22 Hyperfunction of pituitary gland
0.805 0.195 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.804 0.196 0.000
T91 Sequelae of injuries of neck and trunk
0.803 0.197 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.801 0.199 0.000
N60-N64 Disorders of breast
0.800 0.200 0.000
Chapter XXII Codes for special purposes
0.797 0.203 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.797 0.203 0.000
E29 Testicular dysfunction
0.795 0.205 0.000
N75 Diseases of Bartholin's gland
0.795 0.205 0.000
Q60-Q64 Congenital malformations of the urinary system
0.794 0.206 0.000
S50-S59 Injuries to the elbow and forearm
0.791 0.209 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.791 0.209 0.000
S10-S19 Injuries to the neck
0.791 0.209 0.000
H92 Otalgia and effusion of ear
0.788 0.212 0.000
I60-I69 Cerebrovascular diseases
0.787 0.213 0.000
S81 Open wound of lower leg
0.786 0.214 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.785 0.215 0.000
H61 Other disorders of external ear
0.784 0.216 0.000
O80-O84 Delivery
0.783 0.217 0.000
H69 Other disorders of Eustachian tube
0.783 0.217 0.000
H74 Other disorders of middle ear and mastoid
0.779 0.221 0.000
N10-N16 Renal tubulo-interstitial diseases
0.777 0.223 0.000
O03 Spontaneous abortion
0.777 0.223 0.000
O36 Maternal care for other known or suspected foetal problems
0.775 0.225 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.771 0.229 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.769 0.231 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.769 0.231 0.000
N03 Chronic nephritic syndrome
0.769 0.231 0.000
T90.9 Sequelae of unspecified injury of head
0.768 0.232 0.000
T79-T79 Certain early complications of trauma
0.765 0.235 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.763 0.237 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.763 0.237 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.763 0.237 0.000
I71 Aortic aneurysm and dissection
0.761 0.239 0.000
N18.2 Chronic kidney disease, stage 2
0.759 0.241 0.000
S05 Injury of eye and orbit
0.756 0.244 0.000
S01.7 Multiple open wounds of head
0.756 0.244 0.000
S62.61 Fracture of other finger (open)
0.756 0.244 0.000
T39.1 4-Aminophenol derivatives
0.755 0.245 0.000
H26.4 After-cataract
0.753 0.247 0.000
V40-V49 Car occupant injured in transport accident
0.753 0.247 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.751 0.249 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.749 0.251 0.000
N02.9 Unspecified
0.748 0.252 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.747 0.253 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.747 0.253 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.747 0.253 0.000
Y48 Anaesthetics and therapeutic gases
0.747 0.253 0.000
O72 Postpartum haemorrhage
0.746 0.254 0.000
O44 Placenta praevia
0.746 0.254 0.000
H43.1 Vitreous haemorrhage
0.746 0.254 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.745 0.255 0.000
E28 Ovarian dysfunction
0.745 0.255 0.000
H44 Disorders of globe
0.744 0.256 0.000
S70-S79 Injuries to the hip and thigh
0.744 0.256 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.744 0.256 0.000
T92 Sequelae of injuries of upper limb
0.743 0.257 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.743 0.257 0.000
Y86 Sequelae of other accidents
0.741 0.259 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.740 0.260 0.000
S60 Superficial injury of wrist and hand
0.739 0.261 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.738 0.262 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.738 0.262 0.000
Y44 Agents primarily affecting blood constituents
0.736 0.263 0.000
S81.8 Open wound of other parts of lower leg
0.735 0.265 0.000
S01.8 Open wound of other parts of head
0.732 0.268 0.000
S62.50 Fracture of thumb (closed)
0.731 0.269 0.000
H50.9 Strabismus, unspecified
0.731 0.269 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.730 0.270 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.729 0.271 0.000
Y52 Agents primarily affecting the cardiovascular system
0.729 0.271 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.728 0.272 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.728 0.272 0.000
S02 Fracture of skull and facial bones
0.727 0.273 0.000
T90.4 Sequelae of injury of eye and orbit
0.727 0.273 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.727 0.273 0.000
S01.1 Open wound of eyelid and periocular area
0.727 0.273 0.000
N05 Unspecified nephritic syndrome
0.725 0.275 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.724 0.276 0.000
O70 Perineal laceration during delivery
0.724 0.276 0.000
N76 Other inflammation of vagina and vulva
0.723 0.277 0.000
O32.2 Maternal care for transverse and oblique lie
0.722 0.278 0.000
V20-V29 Motorcycle rider injured in transport accident
0.721 0.278 0.000
O85-O92 Complications predominantly related to the puerperium
0.721 0.279 0.000
Y40 Systemic antibiotics
0.721 0.279 0.000
H10 Conjunctivitis
0.719 0.281 0.000
H20 Iridocyclitis
0.718 0.282 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N18.8 Other chronic renal failure
0.717 0.283 0.000
N18.1 Chronic kidney disease, stage 1
0.717 0.283 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.717 0.283 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.716 0.284 0.000
H21 Other disorders of iris and ciliary body
0.716 0.284 0.000
E40-E46 Malnutrition
0.715 0.285 0.000
S40-S49 Injuries to the shoulder and upper arm
0.714 0.286 0.000
S62.2 Fracture of first metacarpal bone
0.714 0.286 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.714 0.286 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.714 0.286 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.714 0.286 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.714 0.286 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.714 0.286 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.714 0.286 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.714 0.286 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.714 0.286 0.000
T36 Poisoning by systemic antibiotics
0.714 0.286 0.000
O45 Premature separation of placenta [abruptio placentae]
0.713 0.287 0.000
O43 Placental disorders
0.713 0.287 0.000
O33 Maternal care for known or suspected disproportion
0.713 0.287 0.000
O31 Complications specific to multiple gestation
0.713 0.287 0.000
O40 Polyhydramnios
0.713 0.287 0.000
H43.8 Other disorders of vitreous body
0.713 0.287 0.000
T78 Adverse effects, not elsewhere classified
0.713 0.287 0.000
Chapter VI Diseases of the nervous system
0.712 0.288 0.000
O71 Other obstetric trauma
0.712 0.288 0.000
E85 Amyloidosis
0.712 0.288 0.000
E84 Cystic fibrosis
0.712 0.288 0.000
E79 Disorders of purine and pyrimidine metabolism
0.712 0.288 0.000
E77 Disorders of glycoprotein metabolism
0.712 0.288 0.000
E76 Disorders of glycosaminoglycan metabolism
0.712 0.288 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.712 0.288 0.000
E74 Other disorders of carbohydrate metabolism
0.712 0.288 0.000
E73 Lactose intolerance
0.712 0.288 0.000
E72 Other disorders of amino-acid metabolism
0.712 0.288 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.712 0.288 0.000
E70 Disorders of aromatic amino-acid metabolism
0.712 0.288 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.712 0.288 0.000
N17.8 Other acute renal failure
0.711 0.289 0.000
N17.2 Acute renal failure with medullary necrosis
0.711 0.289 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.711 0.289 0.000
N17.0 Acute renal failure with tubular necrosis
0.711 0.289 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.710 0.289 0.000
E88 Other metabolic disorders
0.710 0.290 0.000
T90.5 Sequelae of intracranial injury
0.710 0.290 0.000
H90.0 Conductive hearing loss, bilateral
0.709 0.290 0.000
Y57 Other and unspecified drugs and medicaments
0.708 0.291 0.000
N63 Unspecified lump in breast
0.709 0.291 0.000
Q61 Cystic kidney disease
0.707 0.293 0.000
N71.9 Inflammatory disease of uterus, unspecified
0.705 0.295 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.705 0.295 0.000
E87.4 Mixed disorder of acid-base balance
0.705 0.295 0.000
S01.2 Open wound of nose
0.704 0.296 0.000
I73 Other peripheral vascular diseases
0.704 0.296 0.000
H72.0 Central perforation of tympanic membrane
0.703 0.297 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.703 0.297 0.000
E34 Other endocrine disorders
0.703 0.297 0.000
E32 Diseases of thymus
0.703 0.297 0.000
E31 Polyglandular dysfunction
0.703 0.297 0.000
E30 Disorders of puberty, not elsewhere classified
0.703 0.297 0.000
E26 Hyperaldosteronism
0.703 0.297 0.000
E25 Adrenogenital disorders
0.703 0.297 0.000
E24 Cushing's syndrome
0.703 0.297 0.000
E20 Hypoparathyroidism
0.703 0.297 0.000
O03.9 Complete or unspecified, without complication
0.702 0.297 0.000
T98 Sequelae of other and unspecified effects of external causes
0.700 0.299 0.000
T95 Sequelae of burns, corrosions and frostbite
0.700 0.299 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.700 0.299 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.700 0.299 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.700 0.299 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.700 0.300 0.000
T93.1 Sequelae of fracture of femur
0.700 0.300 0.000
O41.0 Oligohydramnios
0.699 0.301 0.000
Y35-Y36 Legal intervention and operations of war
0.697 0.303 0.000
Y10-Y34 Event of undetermined intent
0.697 0.303 0.000
Y00-Y09 Assault
0.697 0.303 0.000
X85-X99 Assault
0.697 0.303 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.697 0.303 0.000
X50-X57 Overexertion, travel and privation
0.697 0.303 0.000
X30-X39 Exposure to forces of nature
0.697 0.303 0.000
X20-X29 Contact with venomous animals and plants
0.697 0.303 0.000
X10-X19 Contact with heat and hot substances
0.697 0.303 0.000
X00-X09 Exposure to smoke, fire and flames
0.697 0.303 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.697 0.303 0.000
W75-W84 Other accidental threats to breathing
0.697 0.303 0.000
W65-W74 Accidental drowning and submersion
0.697 0.303 0.000
W50-W64 Exposure to animate mechanical forces
0.697 0.303 0.000
V98-V99 Other and unspecified transport accidents
0.697 0.303 0.000
V95-V97 Air and space transport accidents
0.697 0.303 0.000
V90-V94 Water transport accidents
0.697 0.303 0.000
V80-V89 Other land transport accidents
0.697 0.303 0.000
V70-V79 Bus occupant injured in transport accident
0.697 0.303 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.697 0.303 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.697 0.303 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.697 0.303 0.000
V01-V09 Pedestrian injured in transport accident
0.697 0.303 0.000
E83 Disorders of mineral metabolism
0.697 0.303 0.000
I74 Arterial embolism and thrombosis
0.697 0.303 0.000
S65 Injury of blood vessels at wrist and hand level
0.696 0.304 0.000
Q00-Q07 Congenital malformations of the nervous system
0.696 0.304 0.000
T43.9 Psychotropic drug, unspecified
0.695 0.305 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.695 0.305 0.000
T43.6 Psychostimulants with abuse potential
0.695 0.305 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.695 0.305 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.695 0.305 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.695 0.305 0.000
H66 Suppurative and unspecified otitis media
0.695 0.305 0.000
Q50-Q56 Congenital malformations of genital organs
0.694 0.306 0.000
H73 Other disorders of tympanic membrane
0.693 0.307 0.000
V10-V19 Pedal cyclist injured in transport accident
0.693 0.307 0.000
T93.0 Sequelae of open wound of lower limb
0.693 0.307 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.693 0.307 0.000
H90.2 Conductive hearing loss, unspecified
0.692 0.308 0.000
E23.0 Hypopituitarism
0.692 0.308 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.692 0.308 0.000
N26 Unspecified contracted kidney
0.692 0.308 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.690 0.310 0.000
S20-S29 Injuries to the thorax
0.689 0.311 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.686 0.313 0.000
S62.3 Fracture of other metacarpal bone
0.685 0.315 0.000
E89.0 Postprocedural hypothyroidism
0.685 0.315 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.685 0.315 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.683 0.317 0.000
H70 Mastoiditis and related conditions
0.683 0.317 0.000
H68 Eustachian salpingitis and obstruction
0.683 0.317 0.000
H67 Otitis media in diseases classified elsewhere
0.683 0.317 0.000
H72.8 Other perforations of tympanic membrane
0.683 0.317 0.000
H55-H59 Other disorders of eye and adnexa
0.682 0.318 0.000
H60.3 Other infective otitis externa
0.682 0.318 0.000
H60.8 Other otitis externa
0.681 0.319 0.000
N61 Inflammatory disorders of breast
0.679 0.321 0.000
S62.7 Multiple fractures of fingers
0.679 0.321 0.000
S62.4 Multiple fractures of metacarpal bones
0.679 0.321 0.000
S62.1 Fracture of other carpal bone(s)
0.679 0.321 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.678 0.322 0.000
O32.8 Maternal care for other malpresentation of foetus
0.678 0.322 0.000
O32.6 Maternal care for compound presentation
0.678 0.322 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.678 0.322 0.000
O32.4 Maternal care for high head at term
0.678 0.322 0.000
O32.3 Maternal care for face, brow and chin presentation
0.678 0.322 0.000
O32.0 Maternal care for unstable lie
0.678 0.322 0.000
W17 Other fall from one level to another
0.678 0.322 0.000
H60.1 Cellulitis of external ear
0.678 0.322 0.000
E87.3 Alkalosis
0.677 0.323 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.677 0.323 0.000
O61 Failed induction of labour
0.677 0.323 0.000
H52 Disorders of refraction and accommodation
0.675 0.325 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.675 0.325 0.000
H34 Retinal vascular occlusions
0.674 0.326 0.000
Y59 Other and unspecified vaccines and biological substances
0.674 0.326 0.000
Y58 Bacterial vaccines
0.674 0.326 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.674 0.326 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.674 0.326 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.674 0.326 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.674 0.326 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.674 0.326 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.674 0.326 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.674 0.326 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.674 0.326 0.000
H36 Retinal disorders in diseases classified elsewhere
0.672 0.327 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.672 0.328 0.000
N06 Isolated proteinuria with specified morphological lesion
0.672 0.328 0.000
N04 Nephrotic syndrome
0.672 0.328 0.000
N01 Rapidly progressive nephritic syndrome
0.672 0.328 0.000
N00 Acute nephritic syndrome
0.672 0.328 0.000
H26.2 Complicated cataract
0.672 0.328 0.000
H49 Paralytic strabismus
0.672 0.328 0.000
N75.1 Abscess of Bartholin's gland
0.672 0.328 0.000
O82 Single delivery by Caesarean section
0.672 0.328 0.000
H90.5 Sensorineural hearing loss, unspecified
0.672 0.328 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.671 0.329 0.000
E21.4 Other specified disorders of parathyroid gland
0.671 0.329 0.000
E21.2 Other hyperparathyroidism
0.671 0.329 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.671 0.329 0.000
H93 Other disorders of ear, not elsewhere classified
0.670 0.330 0.000
Y43 Primarily systemic agents
0.669 0.331 0.000
O42.9 Premature rupture of membranes, unspecified
0.669 0.331 0.000
O66 Other obstructed labour
0.668 0.332 0.000
O73 Retained placenta and membranes, without haemorrhage
0.668 0.332 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.668 0.332 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.666 0.334 0.000
S08 Traumatic amputation of part of head
0.666 0.334 0.000
S07 Crushing injury of head
0.666 0.334 0.000
S04 Injury of cranial nerves
0.666 0.334 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.666 0.334 0.000
Y42.5 Other oestrogens and progestogens
0.666 0.334 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.666 0.334 0.000
T40.4 Other synthetic narcotics
0.666 0.334 0.000
X60-X84 Intentional self-harm
0.664 0.335 0.000
S01.4 Open wound of cheek and temporomandibular area
0.664 0.336 0.000
G90-G99 Other disorders of the nervous system
0.664 0.336 0.000
S82 Fracture of lower leg, including ankle
0.662 0.337 0.000
E29.1 Testicular hypofunction
0.662 0.338 0.000
S80 Superficial injury of lower leg
0.662 0.338 0.000
S86 Injury of muscle and tendon at lower leg level
0.662 0.338 0.000
H69.9 Eustachian tube disorder, unspecified
0.661 0.339 0.000
E16 Other disorders of pancreatic internal secretion
0.661 0.339 0.000
H27 Other disorders of lens
0.660 0.340 0.000
S90-S99 Injuries to the ankle and foot
0.659 0.341 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.659 0.341 0.000
O15 Eclampsia
0.657 0.343 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.657 0.343 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.657 0.343 0.000
H50.1 Divergent concomitant strabismus
0.657 0.343 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.657 0.343 0.000
Q80-Q89 Other congenital malformations
0.657 0.343 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.657 0.343 0.000
Q35-Q37 Cleft lip and cleft palate
0.657 0.343 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.657 0.343 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.657 0.343 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.656 0.344 0.000
H72.2 Other marginal perforations of tympanic membrane
0.656 0.344 0.000
H72.1 Attic perforation of tympanic membrane
0.656 0.344 0.000
I61 Intracerebral haemorrhage
0.656 0.344 0.000
E78.5 Hyperlipidaemia, unspecified
0.656 0.344 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.655 0.345 0.000
T90.8 Sequelae of other specified injuries of head
0.654 0.346 0.000
T90.3 Sequelae of injury of cranial nerves
0.654 0.346 0.000
T90.1 Sequelae of open wound of head
0.654 0.346 0.000
T90.0 Sequelae of superficial injury of head
0.654 0.346 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.652 0.348 0.000
O74 Complications of anaesthesia during labour and delivery
0.650 0.350 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.650 0.350 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.650 0.350 0.000
O60 Preterm delivery
0.650 0.350 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.649 0.351 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.648 0.351 0.000
N03.9 Unspecified
0.648 0.352 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.648 0.352 0.000
H95.1 Other disorders following mastoidectomy
0.647 0.353 0.000
O47.9 False labour, unspecified
0.647 0.353 0.000
E87.2 Acidosis
0.646 0.354 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.646 0.354 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.645 0.355 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.644 0.355 0.000
H51 Other disorders of binocular movement
0.644 0.356 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.643 0.357 0.000
H92.0 Otalgia
0.642 0.358 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.641 0.358 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.641 0.358 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.641 0.358 0.000
T42.3 Barbiturates
0.641 0.358 0.000
T42.2 Succinimides and oxazolidinediones
0.641 0.358 0.000
T42.1 Iminostilbenes
0.641 0.358 0.000
T42.0 Hydantoin derivatives
0.641 0.358 0.000
H26.1 Traumatic cataract
0.641 0.359 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.640 0.360 0.000
E87.6 Hypokalaemia
0.639 0.361 0.000
O30 Multiple gestation
0.638 0.362 0.000
Chapter V Mental and behavioural disorders
0.638 0.362 0.000
H16 Keratitis
0.637 0.362 0.000
O03.4 Incomplete, without complication
0.637 0.362 0.000
H10.9 Conjunctivitis, unspecified
0.637 0.363 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.637 0.363 0.000
N70 Salpingitis and oophoritis
0.637 0.363 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.637 0.363 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.637 0.363 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.637 0.363 0.000
H26.0 Infantile, juvenile and presenile cataract
0.636 0.363 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.636 0.364 0.000
H91.8 Other specified hearing loss
0.636 0.364 0.000
H91.3 Deaf mutism, not elsewhere classified
0.636 0.364 0.000
H91.2 Sudden idiopathic hearing loss
0.636 0.364 0.000
H91.1 Presbycusis
0.636 0.364 0.000
H91.0 Ototoxic hearing loss
0.636 0.364 0.000
W06 Fall involving bed
0.636 0.364 0.000
S69 Other and unspecified injuries of wrist and hand
0.635 0.365 0.000
S89 Other and unspecified injuries of lower leg
0.635 0.365 0.000
S88 Traumatic amputation of lower leg
0.635 0.365 0.000
S87 Crushing injury of lower leg
0.635 0.365 0.000
S85 Injury of blood vessels at lower leg level
0.635 0.365 0.000
S84 Injury of nerves at lower leg level
0.635 0.365 0.000
E27 Other disorders of adrenal gland
0.634 0.365 0.000
H26.9 Cataract, unspecified
0.635 0.365 0.000
H61.2 Impacted cerumen
0.634 0.366 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.634 0.366 0.000
E22.1 Hyperprolactinaemia
0.633 0.366 0.000
S19 Other and unspecified injuries of neck
0.633 0.367 0.000
H61.1 Non-infective disorders of pinna
0.633 0.367 0.000
E87.0 Hyperosmolality and hypernatraemia
0.632 0.367 0.000
H60.9 Otitis externa, unspecified
0.632 0.368 0.000
N99-N99 Other disorders of the genitourinary system
0.631 0.369 0.000
E89.2 Postprocedural hypoparathyroidism
0.630 0.370 0.000
H26.8 Other specified cataract
0.629 0.371 0.000
O62 Abnormalities of forces of labour
0.628 0.372 0.000
N73.8 Other specified female pelvic inflammatory diseases
0.628 0.372 0.000
N73.5 Female pelvic peritonitis, unspecified
0.628 0.372 0.000
N73.4 Female chronic pelvic peritonitis
0.628 0.372 0.000
N73.3 Female acute pelvic peritonitis
0.628 0.372 0.000
N73.2 Unspecified parametritis and pelvic cellulitis
0.628 0.372 0.000
N73.1 Chronic parametritis and pelvic cellulitis
0.628 0.372 0.000
N73.0 Acute parametritis and pelvic cellulitis
0.628 0.372 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.627 0.373 0.000
S52 Fracture of forearm
0.625 0.375 0.000
Y88 Sequelae of surgical and medical care as external cause
0.624 0.375 0.000
S67 Crushing injury of wrist and hand
0.624 0.376 0.000
O00 Ectopic pregnancy
0.622 0.377 0.000
H44.2 Degenerative myopia
0.622 0.378 0.000
S64 Injury of nerves at wrist and hand level
0.621 0.379 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.621 0.379 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.621 0.379 0.000
H17 Corneal scars and opacities
0.621 0.379 0.000
H15 Disorders of sclera
0.621 0.379 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.620 0.380 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.620 0.380 0.000
O70.0 First degree perineal laceration during delivery
0.619 0.381 0.000
T91.1 Sequelae of fracture of spine
0.618 0.382 0.000
Q61.2 Polycystic kidney, adult type
0.618 0.382 0.000
Y42.7 Androgens and anabolic congeners
0.618 0.382 0.000
I73.9 Peripheral vascular disease, unspecified
0.618 0.382 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.617 0.382 0.000
N27 Small kidney of unknown cause
0.617 0.382 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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