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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2972143
log Bayes Factor = 16.1262
Chromosome 2   position 227,116,365  (GRCh37) Explore rs2972143 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.9 Without complications
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.001 0.999
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.001 0.999
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.006 0.994
I25.1 Atherosclerotic heart disease
0.000 0.013 0.987
I25.5 Ischaemic cardiomyopathy
0.000 0.052 0.948
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.150 0.850
I20-I25 Ischaemic heart diseases
0.000 0.217 0.783
I20.9 Angina pectoris, unspecified
0.000 0.218 0.782
I20 Angina pectoris
0.000 0.222 0.778
E11 Non-insulin-dependent diabetes mellitus
0.000 0.236 0.764
E11.3 With ophthalmic complications
0.000 0.262 0.738
I25.3 Aneurysm of heart
0.000 0.275 0.725
I25.6 Silent myocardial ischaemia
0.000 0.293 0.707
I25.2 Old myocardial infarction
0.000 0.313 0.687
E78.0 Pure hypercholesterolaemia
0.000 0.325 0.675
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.327 0.673
E78.5 Hyperlipidaemia, unspecified
0.000 0.352 0.648
I20.0 Unstable angina
0.000 0.373 0.627
E10-E14 Diabetes mellitus
0.000 0.376 0.624
I22 Subsequent myocardial infarction
0.000 0.382 0.618
E10 Insulin-dependent diabetes mellitus
0.000 0.405 0.595
E78.4 Other hyperlipidaemia
0.000 0.408 0.592
E78.2 Mixed hyperlipidaemia
0.000 0.409 0.591
E78.1 Pure hyperglyceridaemia
0.000 0.421 0.579
E11.8 With unspecified complications
0.000 0.423 0.577
E10.1 With ketoacidosis
0.000 0.423 0.577
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.426 0.574
E78.8 Other disorders of lipoprotein metabolism
0.000 0.432 0.568
E11.7 With multiple complications
0.000 0.452 0.548
E11.4 With neurological complications
0.000 0.461 0.539
E10.5 With peripheral circulatory complications
0.000 0.482 0.518
E13 Other specified diabetes mellitus
0.000 0.484 0.516
E11.6 With other specified complications
0.000 0.508 0.492
E10.8 With unspecified complications
0.000 0.517 0.483
E10.0 With coma
0.000 0.531 0.469
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.532 0.468
E11.0 With coma
0.000 0.533 0.467
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.534 0.466
E13.9 Without complications
0.000 0.543 0.457
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.545 0.455
I22.8 Subsequent myocardial infarction of other sites
0.000 0.552 0.448
E12 Malnutrition-related diabetes mellitus
0.000 0.553 0.447
E78.3 Hyperchylomicronaemia
0.000 0.556 0.444
I25.4 Coronary artery aneurysm
0.001 0.563 0.437
E11.1 With ketoacidosis
0.000 0.572 0.428
E10.7 With multiple complications
0.000 0.574 0.426
I23 Certain current complications following acute myocardial infarction
0.000 0.581 0.418
E78.6 Lipoprotein deficiency
0.000 0.612 0.388
E10.6 With other specified complications
0.000 0.614 0.386
E10.3 With ophthalmic complications
0.000 0.626 0.374
E13.8 With unspecified complications
0.000 0.630 0.370
E13.7 With multiple complications
0.000 0.630 0.370
E13.6 With other specified complications
0.000 0.630 0.370
E13.5 With peripheral circulatory complications
0.000 0.630 0.370
E13.4 With neurological complications
0.000 0.630 0.370
E13.2 With renal complications
0.000 0.630 0.370
E13.1 With ketoacidosis
0.000 0.630 0.370
E13.0 With coma
0.000 0.630 0.370
E10.9 Without complications
0.000 0.634 0.366
E10.2 With renal complications
0.000 0.647 0.353
E11.2 With renal complications
0.000 0.647 0.353
E13.3 With ophthalmic complications
0.000 0.676 0.324
E10.4 With neurological complications
0.000 0.676 0.323
I20.8 Other forms of angina pectoris
0.000 0.677 0.323
I24 Other acute ischaemic heart diseases
0.000 0.679 0.321
I20.1 Angina pectoris with documented spasm
0.000 0.679 0.321
E12.9 Without complications
0.000 0.679 0.321
E12.8 With unspecified complications
0.000 0.679 0.321
E12.7 With multiple complications
0.000 0.679 0.321
E12.6 With other specified complications
0.000 0.679 0.321
E12.5 With peripheral circulatory complications
0.000 0.679 0.321
E12.4 With neurological complications
0.000 0.679 0.321
E12.3 With ophthalmic complications
0.000 0.679 0.321
E12.2 With renal complications
0.000 0.679 0.321
E12.1 With ketoacidosis
0.000 0.679 0.321
E12.0 With coma
0.000 0.679 0.321
T36-T50 Poisoning by drugs, medicaments and biological substances
0.307 0.693 0.000
E11.5 With peripheral circulatory complications
0.000 0.697 0.303
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.700 0.300
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.700 0.300
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.700 0.300
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.700 0.300
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.700 0.300
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.700 0.300
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.298 0.702 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.291 0.709 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.289 0.711 0.000
E14 Unspecified diabetes mellitus
0.000 0.711 0.289
T46 Poisoning by agents primarily affecting the cardiovascular system
0.286 0.714 0.000
T42.4 Benzodiazepines
0.285 0.715 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.283 0.717 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.272 0.728 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.265 0.735 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.264 0.736 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.263 0.737 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.001 0.738 0.261
I24.1 Dressler's syndrome
0.000 0.746 0.254
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.249 0.751 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.247 0.753 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.240 0.760 0.000
T40.6 Other and unspecified narcotics
0.239 0.761 0.000
T42.0 Hydantoin derivatives
0.237 0.763 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.237 0.763 0.000
T40.2 Other opioids
0.233 0.767 0.000
T46.1 Calcium-channel blockers
0.231 0.768 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.231 0.769 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.231 0.769 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.230 0.770 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.230 0.770 0.000
T38.1 Thyroid hormones and substitutes
0.230 0.770 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.229 0.771 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.228 0.772 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.224 0.775 0.000
I23.8 Other current complications following acute myocardial infarction
0.001 0.779 0.221
T41 Poisoning by anaesthetics and therapeutic gases
0.220 0.780 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.217 0.783 0.000
T42.3 Barbiturates
0.216 0.784 0.000
E14.4 With neurological complications
0.000 0.785 0.215
T46.4 Angiotensin-converting-enzyme inhibitors
0.215 0.785 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.214 0.786 0.000
T42.2 Succinimides and oxazolidinediones
0.214 0.786 0.000
T36 Poisoning by systemic antibiotics
0.213 0.787 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.789 0.211
T46.5 Other antihypertensive drugs, not elsewhere classified
0.211 0.789 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.210 0.790 0.000
I24.8 Other forms of acute ischaemic heart disease
0.000 0.791 0.209
T38.9 Other and unspecified hormone antagonists
0.209 0.791 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.209 0.791 0.000
T38.7 Androgens and anabolic congeners
0.209 0.791 0.000
T38.5 Other oestrogens and progestogens
0.209 0.791 0.000
T38.4 Oral contraceptives
0.209 0.791 0.000
T38.2 Antithyroid drugs
0.209 0.791 0.000
T38.0 Glucocorticoids and synthetic analogues
0.209 0.791 0.000
T50.7 Analeptics and opioid receptor antagonists
0.207 0.793 0.000
T50.5 Appetite depressants
0.207 0.793 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.207 0.793 0.000
T50.1 Loop [high-ceiling] diuretics
0.207 0.793 0.000
T50.0 Mineralocorticoids and their antagonists
0.207 0.793 0.000
E14.7 With multiple complications
0.000 0.793 0.207
E14.5 With peripheral circulatory complications
0.000 0.793 0.207
E14.0 With coma
0.000 0.793 0.207
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.206 0.794 0.000
T40.1 Heroin
0.206 0.794 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.205 0.795 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.205 0.795 0.000
T46.7 Peripheral vasodilators
0.205 0.795 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.205 0.795 0.000
E14.2 Withrenal complications
0.000 0.795 0.205
T40.5 Cocaine
0.205 0.795 0.000
E14.8 With unspecified complications
0.000 0.795 0.204
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.204 0.796 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.204 0.796 0.000
T47.0 Histamine H(2)-receptor antagonists
0.203 0.797 0.000
T43.6 Psychostimulants with abuse potential
0.202 0.798 0.000
T50.4 Drugs affecting uric acid metabolism
0.200 0.800 0.000
E14.3 With ophthalmic complications
0.000 0.800 0.200
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.200 0.800 0.000
E14.9 Without complications
0.000 0.802 0.198
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.195 0.805 0.000
T40.8 Lysergide [LSD]
0.195 0.805 0.000
T40.7 Cannabis (derivatives)
0.195 0.805 0.000
T40.3 Methadone
0.195 0.805 0.000
T40.0 Opium
0.195 0.805 0.000
T47.4 Other laxatives
0.194 0.806 0.000
T50.8 Diagnostic agents
0.191 0.809 0.000
T43.9 Psychotropic drug, unspecified
0.190 0.809 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.190 0.809 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.190 0.810 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.189 0.810 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.189 0.810 0.000
T47.7 Emetics
0.189 0.810 0.000
T47.6 Antidiarrhoeal drugs
0.189 0.810 0.000
T47.5 Digestants
0.189 0.810 0.000
T47.3 Saline and osmotic laxatives
0.189 0.810 0.000
T47.2 Stimulant laxatives
0.189 0.810 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.187 0.813 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.185 0.815 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.180 0.820 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.176 0.824 0.000
T42.1 Iminostilbenes
0.176 0.824 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.175 0.825 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.171 0.829 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.170 0.830 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.170 0.830 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.170 0.830 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.170 0.830 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.170 0.830 0.000
T44.0 Anticholinesterase agents
0.170 0.830 0.000
E14.6 With other specified complications
0.000 0.830 0.169
I21 Acute myocardial infarction
0.000 0.831 0.169
T36.4 Tetracyclines
0.166 0.834 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.165 0.834 0.000
T37.5 Antiviral drugs
0.165 0.834 0.000
T37.4 Anthelminthics
0.165 0.834 0.000
T37.3 Other antiprotozoal drugs
0.165 0.834 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.165 0.834 0.000
T37.1 Antimycobacterial drugs
0.165 0.834 0.000
T37.0 Sulphonamides
0.165 0.834 0.000
T49.9 Topical agent, unspecified
0.165 0.835 0.000
T49.8 Other topical agents
0.165 0.835 0.000
T49.7 Dental drugs, topically applied
0.165 0.835 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.165 0.835 0.000
T49.5 Ophthalmological drugs and preparations
0.165 0.835 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.165 0.835 0.000
T49.3 Emollients, demulcents and protectants
0.165 0.835 0.000
T49.2 Local astringents and local detergents
0.165 0.835 0.000
T49.1 Antipruritics
0.165 0.835 0.000
T43.2 Other and unspecified antidepressants
0.163 0.837 0.000
T41.5 Therapeutic gases
0.158 0.842 0.000
T41.4 Anaesthetic, unspecified
0.158 0.842 0.000
T41.3 Local anaesthetics
0.158 0.842 0.000
T41.2 Other and unspecified general anaesthetics
0.158 0.842 0.000
T41.1 Intravenous anaesthetics
0.158 0.842 0.000
T41.0 Inhaled anaesthetics
0.158 0.842 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.158 0.842 0.000
T36.9 Systemic antibiotic, unspecified
0.153 0.847 0.000
T36.8 Other systemic antibiotics
0.153 0.847 0.000
T36.7 Antifungal antibiotics, systemically used
0.153 0.847 0.000
T36.6 Rifamycins
0.153 0.847 0.000
T36.5 Aminoglycosides
0.153 0.847 0.000
T36.3 Macrolides
0.153 0.847 0.000
T36.2 Chloramphenicol group
0.153 0.847 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.153 0.847 0.000
E14.1 With ketoacidosis
0.000 0.853 0.147
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.146 0.853 0.000
T48.5 Anti-common-cold drugs
0.146 0.853 0.000
T48.4 Expectorants
0.146 0.853 0.000
T48.3 Antitussives
0.146 0.853 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.146 0.853 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.146 0.853 0.000
T48.0 Oxytocic drugs
0.146 0.853 0.000
T45.0 Antiallergic and antiemetic drugs
0.146 0.854 0.000
I21.4 Acute subendocardial myocardial infarction
0.000 0.858 0.142
T45.9 Primarily systemic and haematological agent, unspecified
0.136 0.864 0.000
T45.8 Other primarily systemic and haematological agents
0.136 0.864 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.136 0.864 0.000
T45.6 Fibrinolysis-affecting drugs
0.136 0.864 0.000
T45.4 Iron and its compounds
0.136 0.864 0.000
T45.3 Enzymes, not elsewhere classified
0.136 0.864 0.000
T45.2 Vitamins, not elsewhere classified
0.134 0.865 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.130 0.870 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.129 0.871 0.000
T36.0 Penicillins
0.126 0.873 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.124 0.876 0.000
T40.4 Other synthetic narcotics
0.123 0.876 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.878 0.121
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.882 0.118
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.887 0.113
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.888 0.112
E70-E90 Metabolic disorders
0.000 0.889 0.111
I60 Subarachnoid haemorrhage
0.000 0.893 0.107
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.894 0.106
T45.5 Anticoagulants
0.101 0.899 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.901 0.099
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.904 0.096
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.904 0.096
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.905 0.095
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.908 0.092
E16 Other disorders of pancreatic internal secretion
0.000 0.910 0.090
E73 Lactose intolerance
0.000 0.911 0.089
E85 Amyloidosis
0.000 0.912 0.088
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.915 0.085
E16.2 Hypoglycaemia, unspecified
0.000 0.915 0.085
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.917 0.083
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.918 0.082
E77 Disorders of glycoprotein metabolism
0.000 0.920 0.080
E76 Disorders of glycosaminoglycan metabolism
0.000 0.920 0.080
E72 Other disorders of amino-acid metabolism
0.000 0.920 0.080
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.920 0.080
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.920 0.080
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.920 0.080
E79 Disorders of purine and pyrimidine metabolism
0.000 0.921 0.079
I60.8 Other subarachnoid haemorrhage
0.000 0.921 0.079
I60-I69 Cerebrovascular diseases
0.000 0.923 0.077
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.923 0.077
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.074 0.926 0.000
E70 Disorders of aromatic amino-acid metabolism
0.000 0.926 0.074
E85.4 Organ-limited amyloidosis
0.000 0.926 0.074
E73.9 Lactose intolerance, unspecified
0.000 0.927 0.073
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.928 0.071
E15 Nondiabetic hypoglycaemic coma
0.000 0.929 0.071
Chapter IX Diseases of the circulatory system
0.000 0.929 0.071
E74 Other disorders of carbohydrate metabolism
0.000 0.930 0.070
I67.1 Cerebral aneurysm, nonruptured
0.000 0.930 0.070
E84 Cystic fibrosis
0.000 0.931 0.069
I67 Other cerebrovascular diseases
0.000 0.932 0.068
I61 Intracerebral haemorrhage
0.000 0.932 0.068
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.933 0.066
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.933 0.066
E85.9 Amyloidosis, unspecified
0.000 0.935 0.065
I62 Other nontraumatic intracranial haemorrhage
0.000 0.935 0.065
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.935 0.065
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.935 0.065
E16.4 Abnormal secretion of gastrin
0.000 0.935 0.065
E16.3 Increased secretion of glucagon
0.000 0.935 0.065
E73.8 Other lactose intolerance
0.000 0.936 0.064
E73.1 Secondary lactase deficiency
0.000 0.936 0.064
E73.0 Congenital lactase deficiency
0.000 0.936 0.064
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.936 0.064
E88 Other metabolic disorders
0.000 0.937 0.063
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.937 0.063
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.937 0.063
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.937 0.063
E85.3 Secondary systemic amyloidosis
0.000 0.939 0.061
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.940 0.060
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.940 0.060
E80.2 Other porphyria
0.000 0.941 0.059
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.941 0.059
E16.1 Other hypoglycaemia
0.000 0.942 0.058
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.942 0.058
E71.3 Disorders of fatty-acid metabolism
0.000 0.942 0.057
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.942 0.057
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.942 0.057
E71.0 Maple-syrup-urine disease
0.000 0.942 0.057
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.942 0.057
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.942 0.057
E72.5 Disorders of glycine metabolism
0.000 0.942 0.057
E72.4 Disorders of ornithine metabolism
0.000 0.942 0.057
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.942 0.057
E72.2 Disorders of urea cycle metabolism
0.000 0.942 0.057
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.942 0.057
E72.0 Disorders of amino-acid transport
0.000 0.942 0.057
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.942 0.057
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.942 0.057
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.942 0.057
E76.2 Other mucopolysaccharidoses
0.000 0.942 0.057
E76.1 Mucopolysaccharidosis, type II
0.000 0.942 0.057
E76.0 Mucopolysaccharidosis, type I
0.000 0.942 0.057
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.942 0.057
E77.8 Other disorders of glycoprotein metabolism
0.000 0.942 0.057
E77.1 Defects in glycoprotein degradation
0.000 0.942 0.057
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.942 0.057
E75.6 Lipid storage disorder, unspecified
0.000 0.942 0.057
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.942 0.057
E75.3 Sphingolipidosis, unspecified
0.000 0.942 0.057
E75.2 Other sphingolipidosis
0.000 0.942 0.057
E75.1 Other gangliosidosis
0.000 0.942 0.057
E75.0 GM2 gangliosidosis
0.000 0.942 0.057
E75.5 Other lipid storage disorders
0.000 0.943 0.057
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.943 0.057
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.943 0.057
E79.1 Lesch-Nyhan syndrome
0.000 0.943 0.057
E85.8 Other amyloidosis
0.000 0.943 0.057
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.057 0.943 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.944 0.056
F23 Acute and transient psychotic disorders
0.056 0.944 0.000
E40-E46 Malnutrition
0.000 0.945 0.055
E80.6 Other disorders of bilirubin metabolism
0.000 0.945 0.055
I67.2 Cerebral atherosclerosis
0.000 0.945 0.055
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.945 0.054
T39.4 Antirheumatics, not elsewhere classified
0.053 0.946 0.000
T39.2 Pyrazolone derivatives
0.053 0.946 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.053 0.947 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.947 0.053
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.947 0.053
E70.2 Disorders of tyrosine metabolism
0.000 0.947 0.053
E70.1 Other hyperphenylalaninaemias
0.000 0.947 0.053
E70.0 Classical phenylketonuria
0.000 0.947 0.053
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.947 0.053
F20 Schizophrenia
0.052 0.948 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.052 0.948 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.948 0.051
E80.5 Crigler-Najjar syndrome
0.000 0.948 0.051
E80.3 Defects of catalase and peroxydase
0.000 0.948 0.051
E80.0 Hereditary erythropoietic porphyria
0.000 0.948 0.051
I10-I15 Hypertensive diseases
0.000 0.949 0.051
F29 Unspecified nonorganic psychosis
0.051 0.949 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.950 0.050
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.950 0.050
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.950 0.050
E74.2 Disorders of galactose metabolism
0.000 0.950 0.050
E74.1 Disorders of fructose metabolism
0.000 0.950 0.050
E74.0 Glycogen storage disease
0.000 0.950 0.050
E80.1 Porphyria cutanea tarda
0.000 0.950 0.050
E84.8 Cystic fibrosis with other manifestations
0.000 0.950 0.049
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.950 0.049
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.950 0.049
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.951 0.049
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.951 0.049
I67.5 Moyamoya disease
0.000 0.951 0.049
I67.4 Hypertensive encephalopathy
0.000 0.951 0.049
I67.3 Progressive vascular leukoencephalopathy
0.000 0.951 0.049
I10 Essential (primary) hypertension
0.000 0.951 0.049
F25 Schizoaffective disorders
0.049 0.951 0.000
F20.0 Paranoid schizophrenia
0.049 0.951 0.000
I05-I09 Chronic rheumatic heart diseases
0.000 0.951 0.049
I21.9 Acute myocardial infarction, unspecified
0.000 0.952 0.048
I00-I02 Acute rheumatic fever
0.000 0.952 0.048
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.048 0.952 0.000
E88.9 Metabolic disorder, unspecified
0.000 0.952 0.048
E70.3 Albinism
0.000 0.953 0.047
F23.3 Other acute predominantly delusional psychotic disorders
0.046 0.953 0.000
I62.1 Nontraumatic extradural haemorrhage
0.000 0.953 0.046
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.046 0.954 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.954 0.046
I05 Rheumatic mitral valve diseases
0.000 0.954 0.046
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.954 0.046
F22 Persistent delusional disorders
0.046 0.954 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.955 0.045
I68.0 Cerebral amyloid angiopathy
0.000 0.955 0.045
T39.1 4-Aminophenol derivatives
0.045 0.955 0.000
E50-E64 Other nutritional deficiencies
0.000 0.956 0.044
F25.9 Schizoaffective disorder, unspecified
0.044 0.956 0.000
F20.9 Schizophrenia, unspecified
0.044 0.956 0.000
I05.2 Mitral stenosis with insufficiency
0.000 0.957 0.043
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.957 0.043
E88.3 Tumour lysis syndrome
0.000 0.957 0.043
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.957 0.043
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.957 0.042
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.958 0.042
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.958 0.042
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.958 0.042
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.042 0.958 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.959 0.041
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.959 0.041
F28 Other nonorganic psychotic disorders
0.041 0.959 0.000
F24 Induced delusional disorder
0.041 0.959 0.000
F21 Schizotypal disorder
0.041 0.959 0.000
E88.2 Lipomatosis, not elsewhere classified
0.000 0.959 0.040
F23.8 Other acute and transient psychotic disorders
0.040 0.959 0.000
F23.2 Acute schizophrenia-like psychotic disorder
0.040 0.959 0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia
0.040 0.959 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.960 0.040
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.960 0.040
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.960 0.040
E45 Retarded development following protein-energy malnutrition
0.000 0.960 0.040
E43 Unspecified severe protein-energy malnutrition
0.000 0.960 0.040
E42 Marasmic kwashiorkor
0.000 0.960 0.040
E41 Nutritional marasmus
0.000 0.960 0.040
E40 Kwashiorkor
0.000 0.960 0.040
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.961 0.039
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.961 0.039
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.961 0.039
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.961 0.039
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.961 0.039
F25.2 Schizoaffective disorder, mixed type
0.039 0.961 0.000
E88.8 Other specified metabolic disorders
0.000 0.961 0.039
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.961 0.039
E84.9 Cystic fibrosis, unspecified
0.000 0.961 0.038
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.962 0.038
F20.8 Other schizophrenia
0.038 0.962 0.000
I61.8 Other intracerebral haemorrhage
0.000 0.962 0.038
E65-E68 Obesity and other hyperalimentation
0.000 0.962 0.038
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.962 0.038
F20.6 Simple schizophrenia
0.038 0.962 0.000
F20.4 Postschizophrenic depression
0.038 0.962 0.000
F20.3 Undifferentiated schizophrenia
0.038 0.962 0.000
F20.2 Catatonic schizophrenia
0.038 0.962 0.000
F20.1 Hebephrenic schizophrenia
0.038 0.962 0.000
F22.0 Delusional disorder
0.038 0.962 0.000
I13 Hypertensive heart and renal disease
0.000 0.963 0.037
F25.8 Other schizoaffective disorders
0.035 0.964 0.000
F25.1 Schizoaffective disorder, depressive type
0.035 0.965 0.000
I05.9 Mitral valve disease, unspecified
0.000 0.965 0.035
I05.1 Rheumatic mitral insufficiency
0.000 0.965 0.035
I02 Rheumatic chorea
0.000 0.965 0.034
I01 Rheumatic fever with heart involvement
0.000 0.965 0.034
F22.9 Persistent delusional disorder, unspecified
0.034 0.966 0.000
I05.8 Other mitral valve diseases
0.000 0.967 0.033
I09 Other rheumatic heart diseases
0.000 0.967 0.033
F22.8 Other persistent delusional disorders
0.033 0.967 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.967 0.032
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.968 0.032
E63 Other nutritional deficiencies
0.000 0.968 0.032
E50 Vitamin A deficiency
0.000 0.968 0.032
E60 Dietary zinc deficiency
0.000 0.968 0.032
E59 Dietary selenium deficiency
0.000 0.968 0.032
E52 Niacin deficiency [pellagra]
0.000 0.968 0.032
I05.0 Mitral stenosis
0.000 0.968 0.032
E51 Thiamine deficiency
0.000 0.968 0.032
E58 Dietary calcium deficiency
0.000 0.968 0.032
E56 Other vitamin deficiencies
0.000 0.968 0.032
E89.2 Postprocedural hypoparathyroidism
0.000 0.968 0.031
F40-F48 Neurotic, stress-related and somatoform disorders
0.032 0.968 0.000
I00 Rheumatic fever without mention of heart involvement
0.000 0.969 0.031
E89.0 Postprocedural hypothyroidism
0.000 0.969 0.031
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.969 0.031
E89.1 Postprocedural hypoinsulinaemia
0.000 0.969 0.031
I07 Rheumatic tricuspid valve diseases
0.000 0.969 0.031
F25.0 Schizoaffective disorder, manic type
0.031 0.969 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.969 0.031
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.970 0.030
F45 Somatoform disorders
0.030 0.970 0.000
F44 Dissociative [conversion] disorders
0.030 0.970 0.000
I69 Sequelae of cerebrovascular disease
0.000 0.970 0.030
F40 Phobic anxiety disorders
0.030 0.970 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.971 0.028
E44.0 Moderate protein-energy malnutrition
0.000 0.971 0.028
E61 Deficiency of other nutrient elements
0.000 0.971 0.028
Chapter V Mental and behavioural disorders
0.028 0.972 0.000
E89.5 Postprocedural testicular hypofunction
0.000 0.972 0.028
F20.5 Residual schizophrenia
0.028 0.972 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.972 0.028
I15 Secondary hypertension
0.000 0.972 0.027
E67 Other hyperalimentation
0.000 0.972 0.027
E68 Sequelae of hyperalimentation
0.000 0.972 0.027
F40.0 Agoraphobia
0.027 0.972 0.000
E89.4 Postprocedural ovarian failure
0.000 0.973 0.027
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.973 0.027

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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