TreeWAS – Variant ID: rs2982712

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M16.9 Coxarthrosis, unspecified	0.000	0.668	0.332
S82.80 Fractures of other parts of lower leg (closed)	0.046	0.954	0.000
S82.8 Fractures of other parts of lower leg	0.026	0.974	0.000
D37.5 Rectum	0.000	0.980	0.020
S82.86 Maisonneuve's fracture	0.019	0.981	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.981	0.019
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.981	0.019
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.982	0.018
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.982	0.018
D43.2 Brain, unspecified	0.000	0.982	0.018
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.982	0.018
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.982	0.018
D38.1 Trachea, bronchus and lung	0.000	0.982	0.018
S82.81 Fractures of other parts of lower leg (open)	0.017	0.983	0.000
D45 Polycythaemia vera	0.000	0.983	0.017
D47.4 Osteomyelofibrosis	0.000	0.983	0.017
D37.3 Appendix	0.000	0.984	0.016
D37.9 Digestive organ, unspecified	0.000	0.985	0.015
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.985	0.015
D43.0 Brain, supratentorial	0.000	0.985	0.015
D38.5 Other respiratory organs	0.000	0.985	0.015
S82.40 Fracture of fibula alone (closed)	0.014	0.986	0.000
S82 Fracture of lower leg, including ankle	0.014	0.986	0.000
S82.4 Fracture of fibula alone	0.014	0.986	0.000
D37.1 Stomach	0.000	0.986	0.014
D38.0 Larynx	0.000	0.986	0.014
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.986	0.014
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.986	0.013
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.986	0.014
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.987	0.013
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.987	0.013
D38.6 Respiratory organ, unspecified	0.000	0.987	0.013
D38.4 Thymus	0.000	0.987	0.013
D38.3 Mediastinum	0.000	0.987	0.013
D38.2 Pleura	0.000	0.987	0.013
D43.9 Central nervous system, unspecified	0.000	0.987	0.013
D43.7 Other parts of central nervous system	0.000	0.987	0.013
D43.3 Cranial nerves	0.000	0.987	0.013
S82.3 Fracture of lower end of tibia	0.013	0.987	0.000
D37.2 Small intestine	0.000	0.987	0.013
D40.1 Testis	0.000	0.987	0.013
D43.1 Brain, infratentorial	0.000	0.987	0.013
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.987	0.013
S82.31 Fracture of lower end of tibia (open)	0.013	0.987	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.987	0.012
D37.0 Lip, oral cavity and pharynx	0.000	0.988	0.012
D48.7 Other specified sites	0.000	0.988	0.012
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.012	0.988	0.000
D43.4 Spinal cord	0.000	0.988	0.012
D48.0 Bone and articular cartilage	0.000	0.988	0.012
D40.0 Prostate	0.000	0.989	0.011
D40.9 Male genital organ, unspecified	0.000	0.989	0.011
D40.7 Other male genital organs	0.000	0.989	0.011
M16 Coxarthrosis [arthrosis of hip]	0.000	0.989	0.011
Z50.5 Speech therapy	0.011	0.989	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.989	0.011
D48.6 Breast	0.000	0.989	0.010
S82.0 Fracture of patella	0.010	0.989	0.000
Z98.8 Other specified postsurgical states	0.000	0.990	0.010
S82.41 Fracture of fibula alone (open)	0.010	0.990	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.990	0.010
D42.9 Meninges, unspecified	0.000	0.990	0.010
D42.1 Spinal meninges	0.000	0.990	0.010
D42.0 Cerebral meninges	0.000	0.990	0.010
D48.3 Retroperitoneum	0.000	0.990	0.010
S82.30 Fracture of lower end of tibia (closed)	0.010	0.990	0.000
S82.7 Multiple fractures of lower leg	0.010	0.990	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.990	0.010
D47.2 Monoclonal gammopathy	0.000	0.990	0.010
S82.9 Fracture of lower leg, part unspecified	0.009	0.990	0.000
D48.4 Peritoneum	0.000	0.991	0.009
D46 Myelodysplastic syndromes	0.000	0.991	0.009
S82.5 Fracture of medial malleolus	0.009	0.991	0.000
S82.1 Fracture of upper end of tibia	0.009	0.991	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.991	0.009
M16.0 Primary coxarthrosis, bilateral	0.000	0.991	0.009
M21.0 Valgus deformity, not elsewhere classified	0.009	0.991	0.000
D48.5 Skin	0.000	0.991	0.009
D37.6 Liver, gallbladder and bile ducts	0.000	0.991	0.008
D37.4 Colon	0.000	0.991	0.009
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.000	0.992	0.008
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.008	0.992	0.000
S82.00 Fracture of patella (closed)	0.008	0.992	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.992	0.008
D44.6 Carotid body	0.000	0.992	0.008
M16.4 Posttraumatic coxarthrosis, bilateral	0.000	0.992	0.008
D46.2 Refractory anaemia with excess of blasts	0.000	0.992	0.008
S82.11 Fracture of upper end of tibia (open)	0.007	0.993	0.000
S82.01 Fracture of patella (open)	0.007	0.993	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.000	0.993	0.007
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.993	0.007
S82.51 Fracture of medial malleolus (open)	0.007	0.993	0.000
S82.71 Multiple fractures of lower leg (open)	0.007	0.993	0.000
D46.4 Refractory anaemia, unspecified	0.000	0.993	0.007
D44.5 Pineal gland	0.000	0.993	0.007
D44.2 Parathyroid gland	0.000	0.993	0.007
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.993	0.007
S82.91 Fracture of lower leg, part unspecified (open)	0.007	0.993	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.000	0.993	0.007
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.000	0.993	0.007
D46.3 Refractory anaemia with excess of blasts with transformation	0.000	0.993	0.007
D44.4 Craniopharyngeal duct	0.000	0.993	0.007
D44.1 Adrenal gland	0.000	0.993	0.007
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.993	0.007
D44.8 Pluriglandular involvement	0.000	0.993	0.007
D46.1 Refractory anaemia with sideroblasts	0.000	0.993	0.007
S82.2 Fracture of shaft of tibia	0.007	0.993	0.000
D39.9 Female genital organ, unspecified	0.000	0.993	0.006
D39.2 Placenta	0.000	0.993	0.006
D44.3 Pituitary gland	0.000	0.993	0.007
S82.6 Fracture of lateral malleolus	0.007	0.993	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.006	0.993	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.006	0.993	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.006	0.993	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.006	0.993	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.006	0.993	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.006	0.993	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.006	0.993	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.006	0.993	0.000
D39.7 Other female genital organs	0.000	0.993	0.006
D44.0 Thyroid gland	0.000	0.994	0.006
D44.7 Aortic body and other paraganglia	0.000	0.994	0.006
M81.99 Osteoporosis, unspecified (Site unspecified)	0.006	0.994	0.000
S82.70 Multiple fractures of lower leg (closed)	0.006	0.994	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.006	0.994	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.000	0.994	0.006
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.994	0.006
D46.7 Other myelodysplastic syndromes	0.000	0.994	0.006
D39.0 Uterus	0.000	0.994	0.006
M81.9 Osteoporosis, unspecified	0.006	0.994	0.000
D44.9 Endocrine gland, unspecified	0.000	0.994	0.005
M16.3 Other dysplastic coxarthrosis	0.000	0.994	0.006
D37.7 Other digestive organs	0.000	0.994	0.005
D41.2 Ureter	0.000	0.994	0.005
M16.5 Other posttraumatic coxarthrosis	0.000	0.994	0.005
D41.1 Renal pelvis	0.000	0.994	0.005
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.995	0.005
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
I98.0 Cardiovascular syphilis	0.000	0.995	0.005
D41.9 Urinary organ, unspecified	0.000	0.995	0.005
D41.7 Other urinary organs	0.000	0.995	0.005
D41.3 Urethra	0.000	0.995	0.005
S82.50 Fracture of medial malleolus (closed)	0.005	0.995	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.005	0.995	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.005	0.995	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.005	0.995	0.000
S82.61 Fracture of lateral malleolus (open)	0.005	0.995	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.005	0.995	0.000
D48.1 Connective and other soft tissue	0.000	0.995	0.005
M81.92 Osteoporosis, unspecified (Upper arm)	0.004	0.995	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.004	0.995	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.004	0.996	0.000
M81.98 Osteoporosis, unspecified (Other)	0.004	0.996	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.004	0.996	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.004	0.996	0.000
C45.0 Mesothelioma of pleura	0.004	0.996	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.004	0.996	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.996	0.004
I63 Cerebral infarction	0.004	0.996	0.000
S82.10 Fracture of upper end of tibia (closed)	0.004	0.996	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.004	0.996	0.000
M41.9 Scoliosis, unspecified	0.004	0.996	0.000
D39.1 Ovary	0.000	0.996	0.004
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.004	0.996	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.004	0.996	0.000
Z12.0 Special screening examination for neoplasm of stomach	0.004	0.996	0.000
S82.21 Fracture of shaft of tibia (open)	0.004	0.996	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.004	0.996	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.004	0.996	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.004	0.996	0.000
C45 Mesothelioma	0.004	0.996	0.000
D41.0 Kidney	0.000	0.996	0.003
I34.1 Mitral (valve) prolapse	0.004	0.996	0.000
M54.57 Low back pain (Lumbosacral region)	0.004	0.996	0.000
C45.7 Mesothelioma of other sites	0.003	0.996	0.000
S82.20 Fracture of shaft of tibia (closed)	0.003	0.997	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.003	0.997	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.003	0.997	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.000	0.997	0.003
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
C45.9 Mesothelioma, unspecified	0.003	0.997	0.000
S80-S89 Injuries to the knee and lower leg	0.003	0.997	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.003	0.997	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.003	0.997	0.000
C45.1 Mesothelioma of peritoneum	0.003	0.997	0.000
I63.8 Other cerebral infarction	0.003	0.997	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.003	0.997	0.000
C15.9 Oesophagus, unspecified	0.003	0.997	0.000
M16.7 Other secondary coxarthrosis	0.001	0.997	0.002
Z98 Other postsurgical states	0.000	0.997	0.003
M81 Osteoporosis without pathological fracture	0.003	0.997	0.000
C45.2 Mesothelioma of pericardium	0.003	0.997	0.000
C69.3 Choroid	0.000	0.997	0.003
D34 Benign neoplasm of thyroid gland	0.003	0.997	0.000
D00.0 Lip, oral cavity and pharynx	0.003	0.997	0.000
M79.69 Pain in limb (Site unspecified)	0.003	0.997	0.000
M41 Scoliosis	0.003	0.997	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.003	0.997	0.000
S86 Injury of muscle and tendon at lower leg level	0.003	0.997	0.000
J84 Other interstitial pulmonary diseases	0.000	0.997	0.003
C21.1 Anal canal	0.003	0.997	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.003	0.997	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.002	0.997	0.000
S89 Other and unspecified injuries of lower leg	0.003	0.997	0.000
G96.0 Cerebrospinal fluid leak	0.003	0.997	0.000
S84 Injury of nerves at lower leg level	0.002	0.997	0.000
A41.8 Other specified septicaemia	0.003	0.997	0.000
M81.0 Postmenopausal osteoporosis	0.002	0.997	0.000
S80.8 Other superficial injuries of lower leg	0.003	0.997	0.000
M21 Other acquired deformities of limbs	0.003	0.997	0.000
S88 Traumatic amputation of lower leg	0.002	0.997	0.000
S87 Crushing injury of lower leg	0.002	0.997	0.000
S85 Injury of blood vessels at lower leg level	0.002	0.997	0.000
M41.5 Other secondary scoliosis	0.002	0.997	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.002	0.997	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.002	0.998	0.000
J18.0 Bronchopneumonia, unspecified	0.002	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.998	0.002
M81.8 Other osteoporosis	0.002	0.998	0.000
M81.6 Localised osteoporosis [Lequesne]	0.002	0.998	0.000
M81.5 Idiopathic osteoporosis	0.002	0.998	0.000
M81.2 Osteoporosis of disuse	0.002	0.998	0.000
M81.1 Postoophorectomy osteoporosis	0.002	0.998	0.000
S81.9 Open wound of lower leg, part unspecified	0.002	0.998	0.000
S80 Superficial injury of lower leg	0.002	0.998	0.000
R23.4 Changes in skin texture	0.002	0.998	0.000
M21.8 Other specified acquired deformities of limbs	0.002	0.998	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.002	0.998	0.000
M41.56 Other secondary scoliosis (Lumbar region)	0.002	0.998	0.000
N81.9 Female genital prolapse, unspecified	0.000	0.998	0.002
M21.7 Unequal limb length (acquired)	0.002	0.998	0.000
M21.4 Flat foot [pes planus] (acquired)	0.002	0.998	0.000
S89.8 Other specified injuries of lower leg	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
C92.1 Chronic myeloid leukaemia	0.002	0.998	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
W25.9 Unspecified place	0.000	0.998	0.002
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.002	0.998	0.000
M21.9 Acquired deformity of limb, unspecified	0.002	0.998	0.000
M41.8 Other forms of scoliosis	0.002	0.998	0.000
M81.4 Drug-induced osteoporosis	0.002	0.998	0.000
W06.0 Home	0.000	0.998	0.002
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.001	0.998	0.001
I05.2 Mitral stenosis with insufficiency	0.000	0.998	0.002
M41.4 Neuromuscular scoliosis	0.002	0.998	0.000
M41.3 Thoracogenic scoliosis	0.002	0.998	0.000
M41.2 Other idiopathic scoliosis	0.002	0.998	0.000
M41.1 Juvenile idiopathic scoliosis	0.002	0.998	0.000
M41.0 Infantile idiopathic scoliosis	0.002	0.998	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.002	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.002
S86.0 Injury of Achilles tendon	0.002	0.998	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.002	0.998	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.002	0.998	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.002	0.998	0.000
Z44.3 Fitting and adjustment of external breast prosthesis	0.002	0.998	0.000
G71.1 Myotonic disorders	0.002	0.998	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.002	0.998	0.000
S89.7 Multiple injuries of lower leg	0.002	0.998	0.000
S89.1 Other specified injuries of lower leg	0.002	0.998	0.000
S89.0 Multiple injuries of lower leg	0.002	0.998	0.000
G72.9 Myopathy, unspecified	0.002	0.998	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.002	0.998	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.002	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
R23.3 Spontaneous ecchymoses	0.002	0.998	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.002	0.998	0.000
S84.8 Injury of other nerves at lower leg level	0.002	0.998	0.000
S84.7 Injury of multiple nerves at lower leg level	0.002	0.998	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.002	0.998	0.000
S84.0 Injury of tibial nerve at lower leg level	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.002	0.998	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.002	0.998	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.002	0.998	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.002	0.998	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.002	0.998	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.002	0.998	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.002	0.998	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.002	0.998	0.000
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
Z97.8 Presence of other specified devices	0.000	0.998	0.002
S85.9 Injury of unspecified blood vessel at lower leg level	0.002	0.998	0.000
S85.8 Injury of other blood vessels at lower leg level	0.002	0.998	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.002	0.998	0.000
S85.5 Injury of popliteal vein	0.002	0.998	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.002	0.998	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.002	0.998	0.000
S85.2 Injury of peroneal artery	0.002	0.998	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.002	0.998	0.000
S85.0 Injury of popliteal artery	0.002	0.998	0.000
S87.0 Crushing injury of knee	0.002	0.998	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.002	0.998	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.002	0.998	0.000
S88.0 Traumatic amputation at knee level	0.002	0.998	0.000
Z57.2 Occupational exposure to dust	0.002	0.998	0.000
I05 Rheumatic mitral valve diseases	0.000	0.998	0.002
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
M41.59 Other secondary scoliosis (Site unspecified)	0.002	0.998	0.000
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.57 Other secondary scoliosis (Lumbosacral region)	0.002	0.998	0.000
M41.55 Other secondary scoliosis (Thoracolumbar region)	0.002	0.998	0.000
M41.54 Other secondary scoliosis (Thoracic region)	0.002	0.998	0.000
M41.53 Other secondary scoliosis (Cervicothoracic region)	0.002	0.998	0.000
M41.52 Other secondary scoliosis (Cervical region)	0.002	0.998	0.000
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M41.50 Other secondary scoliosis (Multiple sites in spine)	0.002	0.998	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.002	0.998	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.998	0.002
S86.8 Injury of other muscles and tendons at lower leg level	0.002	0.998	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.002	0.998	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
M21.3 Wrist or foot drop (acquired)	0.002	0.998	0.000
R23.8 Other and unspecified skin changes	0.002	0.998	0.000
S89.9 Unspecified injury of lower leg	0.002	0.998	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.002	0.998	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.998	0.002
S81 Open wound of lower leg	0.002	0.998	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.002	0.998	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.002	0.998	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.002	0.998	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.002	0.998	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.002	0.998	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.002	0.998	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.002	0.998	0.000
M81.28 Osteoporosis of disuse (Other)	0.002	0.998	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.002	0.998	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.002	0.998	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.002	0.998	0.000
M81.24 Osteoporosis of disuse (Hand)	0.002	0.998	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.002	0.998	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.002	0.998	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.002	0.998	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.58 Idiopathic osteoporosis (Other)	0.002	0.998	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.002	0.998	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.002	0.998	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.002	0.998	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.002	0.998	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.002	0.998	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.002	0.998	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.002	0.998	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.002	0.998	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.002	0.998	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.002	0.998	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.002	0.998	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.002	0.998	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.002	0.998	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.002	0.998	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.002	0.998	0.000
M81.89 Other osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.88 Other osteoporosis (Other)	0.002	0.998	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.86 Other osteoporosis (Lower leg)	0.002	0.998	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.84 Other osteoporosis (Hand)	0.002	0.998	0.000
M81.83 Other osteoporosis (Forearm)	0.002	0.998	0.000
M81.82 Other osteoporosis (Upper arm)	0.002	0.998	0.000
M81.81 Other osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.80 Other osteoporosis (Multiple sites)	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
D41.4 Bladder	0.002	0.998	0.000
I85.9 Oesophageal varices without bleeding	0.000	0.998	0.002
J84.0 Alveolar and parietoalveolar conditions	0.000	0.998	0.002
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.002	0.998	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.002	0.998	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.002	0.998	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.002	0.998	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.002	0.998	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.002	0.998	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.002	0.998	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.002	0.998	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.002	0.998	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.002	0.998	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.002	0.998	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.002	0.998	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.002	0.998	0.000
C21.0 Anus, unspecified	0.002	0.998	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.002	0.998	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.002	0.998	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.002	0.998	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.002	0.998	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.002	0.998	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.002	0.998	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.002	0.998	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.002	0.998	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.002	0.998	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.002	0.998	0.000
C67.3 Anterior wall of bladder	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.002	0.998	0.000
M21.78 Unequal limb length (acquired)-Other	0.002	0.998	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.002	0.998	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.002	0.998	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.002	0.998	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.002	0.998	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.002	0.998	0.000
K10.8 Other specified diseases of jaws	0.000	0.998	0.002
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.002	0.998	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.002	0.998	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.002	0.998	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.002	0.998	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.002	0.998	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.002	0.998	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.002	0.998	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.002	0.998	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.002	0.998	0.000
M41.89 Other forms of scoliosis (Site unspecified)	0.002	0.998	0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.87 Other forms of scoliosis (Lumbosacral region)	0.002	0.998	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.002	0.998	0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.002	0.998	0.000
M41.84 Other forms of scoliosis (Thoracic region)	0.002	0.998	0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.002	0.998	0.000
M41.82 Other forms of scoliosis (Cervical region)	0.002	0.998	0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.002	0.998	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.002	0.998	0.000
D00.1 Oesophagus	0.002	0.998	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.002	0.998	0.000
N43.3 Hydrocele, unspecified	0.000	0.998	0.002
M41.09 Infantile idiopathic scoliosis (Site unspecified)	0.002	0.998	0.000
M41.08 Infantile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.07 Infantile idiopathic scoliosis (Lumbosacral region)	0.002	0.998	0.000
M41.06 Infantile idiopathic scoliosis (Lumbar region)	0.002	0.998	0.000
M41.05 Infantile idiopathic scoliosis (Thoracolumbar region)	0.002	0.998	0.000
M41.04 Infantile idiopathic scoliosis (Thoracic region)	0.002	0.998	0.000
M41.03 Infantile idiopathic scoliosis (Cervicothoracic region)	0.002	0.998	0.000
M41.02 Infantile idiopathic scoliosis (Cervical region)	0.002	0.998	0.000
M41.01 Infantile idiopathic scoliosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M41.00 Infantile idiopathic scoliosis (Multiple sites in spine)	0.002	0.998	0.000
M41.19 Juvenile idiopathic scoliosis (Site unspecified)	0.002	0.998	0.000
M41.18 Juvenile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.17 Juvenile idiopathic scoliosis (Lumbosacral region)	0.002	0.998	0.000
M41.16 Juvenile idiopathic scoliosis (Lumbar region)	0.002	0.998	0.000
M41.15 Juvenile idiopathic scoliosis (Thoracolumbar region)	0.002	0.998	0.000
M41.14 Juvenile idiopathic scoliosis (Thoracic region)	0.002	0.998	0.000
M41.13 Juvenile idiopathic scoliosis (Cervicothoracic region)	0.002	0.998	0.000
M41.12 Juvenile idiopathic scoliosis (Cervical region)	0.002	0.998	0.000
M41.11 Juvenile idiopathic scoliosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M41.10 Juvenile idiopathic scoliosis (Multiple sites in spine)	0.002	0.998	0.000
M41.29 Other idiopathic scoliosis (Site unspecified)	0.002	0.998	0.000
M41.28 Other idiopathic scoliosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.27 Other idiopathic scoliosis (Lumbosacral region)	0.002	0.998	0.000
M41.26 Other idiopathic scoliosis (Lumbar region)	0.002	0.998	0.000
M41.25 Other idiopathic scoliosis (Thoracolumbar region)	0.002	0.998	0.000
M41.24 Other idiopathic scoliosis (Thoracic region)	0.002	0.998	0.000
M41.23 Other idiopathic scoliosis (Cervicothoracic region)	0.002	0.998	0.000
M41.22 Other idiopathic scoliosis (Cervical region)	0.002	0.998	0.000
M41.21 Other idiopathic scoliosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M41.20 Other idiopathic scoliosis (Multiple sites in spine)	0.002	0.998	0.000
M41.39 Thoracogenic scoliosis-Site unspe	0.002	0.998	0.000
M41.38 Thoracogenic scoliosis-Sacral/sacrococ	0.002	0.998	0.000
M41.37 Thoracogenic scoliosis-Lumbosacral	0.002	0.998	0.000
M41.36 Thoracogenic scoliosis-Lumbar	0.002	0.998	0.000
M41.35 Thoracogenic scoliosis (Thoracolumbar region)	0.002	0.998	0.000
M41.34 Thoracogenic scoliosis (Thoracic region)	0.002	0.998	0.000
M41.33 Thoracogenic scoliosis (Cervicothoracic region)	0.002	0.998	0.000
M41.32 Thoracogenic scoliosis-Cervical	0.002	0.998	0.000
M41.31 Thoracogenic scoliosis-Occipit-atl-axl	0.002	0.998	0.000
M41.30 Thoracogenic scoliosis (Multiple sites in spine)	0.002	0.998	0.000
M41.49 Neuromuscular scoliosis (Site unspecified)	0.002	0.998	0.000
M41.48 Neuromuscular scoliosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.47 Neuromuscular scoliosis (Lumbosacral region)	0.002	0.998	0.000
M41.46 Neuromuscular scoliosis (Lumbar region)	0.002	0.998	0.000
M41.45 Neuromuscular scoliosis (Thoracolumbar region)	0.002	0.998	0.000
M41.44 Neuromuscular scoliosis (Thoracic region)	0.002	0.998	0.000
M41.43 Neuromuscular scoliosis (Cervicothoracic region)	0.002	0.998	0.000
M41.42 Neuromuscular scoliosis (Cervical region)	0.002	0.998	0.000
M41.41 Neuromuscular scoliosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M41.40 Neuromuscular scoliosis (Multiple sites in spine)	0.002	0.998	0.000
M81.48 Drug-induced osteoporosis (Other)	0.002	0.998	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.002	0.998	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.002	0.998	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.002	0.998	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations