TreeWAS – Variant ID: rs2990510

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C77.2 Intra-abdominal lymph nodes	0.052	0.948	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.051	0.949	0.000
C77.8 Lymph nodes of multiple regions	0.050	0.950	0.000
C77.1 Intrathoracic lymph nodes	0.048	0.952	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.952	0.048
E10.3 With ophthalmic complications	0.000	0.953	0.047
C77.5 Intrapelvic lymph nodes	0.047	0.953	0.000
C77.0 Lymph nodes of head, face and neck	0.045	0.955	0.000
E10.4 With neurological complications	0.000	0.956	0.044
E10.8 With unspecified complications	0.000	0.956	0.044
E10.1 With ketoacidosis	0.000	0.957	0.043
E10.2 With renal complications	0.000	0.958	0.042
C77.4 Inguinal and lower limb lymph nodes	0.039	0.961	0.000
E10.6 With other specified complications	0.000	0.962	0.038
E10.5 With peripheral circulatory complications	0.000	0.964	0.036
E10.7 With multiple complications	0.000	0.966	0.034
C77.9 Lymph node, unspecified	0.031	0.969	0.000
E10.0 With coma	0.000	0.970	0.030
E10-E14 Diabetes mellitus	0.000	0.981	0.019
D13.1 Stomach	0.018	0.982	0.000
I08.0 Disorders of both mitral and aortic valves	0.018	0.982	0.000
Z22.5 Carrier of viral hepatitis	0.018	0.982	0.000
Z02.8 Other examinations for administrative purposes	0.000	0.983	0.017
E11.2 With renal complications	0.000	0.985	0.015
E11 Non-insulin-dependent diabetes mellitus	0.000	0.985	0.015
E11.3 With ophthalmic complications	0.000	0.985	0.015
E14 Unspecified diabetes mellitus	0.000	0.986	0.014
E14.3 With ophthalmic complications	0.000	0.986	0.014
E12 Malnutrition-related diabetes mellitus	0.000	0.986	0.014
E14.4 With neurological complications	0.000	0.987	0.013
E10.9 Without complications	0.000	0.987	0.013
D04.7 Skin of lower limb, including hip	0.012	0.988	0.000
H35.3 Degeneration of macula and posterior pole	0.012	0.988	0.000
E11.8 With unspecified complications	0.000	0.988	0.012
E11.4 With neurological complications	0.000	0.988	0.012
D04.4 Skin of scalp and neck	0.011	0.989	0.000
E14.8 With unspecified complications	0.000	0.989	0.011
S70.9 Superficial injury of hip and thigh, unspecified	0.011	0.989	0.000
E14.2 Withrenal complications	0.000	0.989	0.011
E14.7 With multiple complications	0.000	0.989	0.010
E14.0 With coma	0.000	0.989	0.010
D04 Carcinoma in situ of skin	0.011	0.989	0.000
E14.1 With ketoacidosis	0.000	0.990	0.010
E11.1 With ketoacidosis	0.000	0.990	0.010
E12.9 Without complications	0.000	0.990	0.010
E12.8 With unspecified complications	0.000	0.990	0.010
E12.7 With multiple complications	0.000	0.990	0.010
E12.6 With other specified complications	0.000	0.990	0.010
E12.5 With peripheral circulatory complications	0.000	0.990	0.010
E12.4 With neurological complications	0.000	0.990	0.010
E12.3 With ophthalmic complications	0.000	0.990	0.010
E12.2 With renal complications	0.000	0.990	0.010
E12.1 With ketoacidosis	0.000	0.990	0.010
E12.0 With coma	0.000	0.990	0.010
E13 Other specified diabetes mellitus	0.000	0.990	0.010
E11.0 With coma	0.000	0.990	0.010
E11.7 With multiple complications	0.000	0.990	0.009
E14.5 With peripheral circulatory complications	0.000	0.991	0.009
D04.9 Skin, unspecified	0.009	0.991	0.000
E11.6 With other specified complications	0.000	0.991	0.008
J98.1 Pulmonary collapse	0.009	0.991	0.000
D04.6 Skin of upper limb, including shoulder	0.008	0.992	0.000
D04.5 Skin of trunk	0.008	0.992	0.000
D04.8 Skin of other sites	0.008	0.992	0.000
D04.0 Skin of lip	0.008	0.992	0.000
Z22 Carrier of infectious disease	0.008	0.992	0.000
D04.1 Skin of eyelid, including canthus	0.008	0.992	0.000
E13.8 With unspecified complications	0.000	0.992	0.007
E13.7 With multiple complications	0.000	0.992	0.007
E13.6 With other specified complications	0.000	0.992	0.007
E13.5 With peripheral circulatory complications	0.000	0.992	0.007
E13.4 With neurological complications	0.000	0.992	0.007
E13.2 With renal complications	0.000	0.992	0.007
E13.1 With ketoacidosis	0.000	0.992	0.007
E13.0 With coma	0.000	0.992	0.007
S70 Superficial injury of hip and thigh	0.007	0.993	0.000
E14.6 With other specified complications	0.000	0.993	0.007
Z02 Examination and encounter for administrative purposes	0.000	0.993	0.007
C44.2 Skin of ear and external auricular canal	0.000	0.993	0.007
S70.0 Contusion of hip	0.007	0.993	0.000
S70.8 Other superficial injuries of hip and thigh	0.007	0.993	0.000
D04.3 Skin of other and unspecified parts of face	0.006	0.993	0.000
D04.2 Skin of ear and external auricular canal	0.006	0.993	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.006	0.994	0.000
E13.3 With ophthalmic complications	0.000	0.994	0.006
L81.9 Disorder of pigmentation, unspecified	0.006	0.994	0.000
Z22.8 Carrier of other infectious diseases	0.006	0.994	0.000
I08 Multiple valve diseases	0.006	0.994	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.006	0.994	0.000
Z22.9 Carrier of infectious disease, unspecified	0.006	0.994	0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.006	0.994	0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.006	0.994	0.000
Z22.2 Carrier of diphtheria	0.006	0.994	0.000
Z22.0 Carrier of typhoid	0.006	0.994	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.006	0.994	0.000
E13.9 Without complications	0.000	0.994	0.006
G90 Disorders of autonomic nervous system	0.006	0.994	0.000
G90.3 Multisystem degeneration	0.006	0.994	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.005	0.994	0.000
Z02.9 Examination for administrative purposes, unspecified	0.000	0.994	0.005
Z02.7 Issue of medical certificate	0.000	0.994	0.005
Z02.6 Examination for insurance purposes	0.000	0.994	0.005
Z02.5 Examination for participation in sport	0.000	0.994	0.005
Z02.4 Examination for driving licence	0.000	0.994	0.005
Z02.3 Examination for recruitment to armed forces	0.000	0.994	0.005
Z02.2 Examination for admission to residential institution	0.000	0.994	0.005
Z02.1 Pre-employment examination	0.000	0.994	0.005
Z02.0 Examination for admission to educational institution	0.000	0.994	0.005
D13.3 Other and unspecified parts of small intestine	0.005	0.995	0.000
S52.10 Fracture of upper end of radius (closed)	0.000	0.995	0.005
I08.2 Disorders of both aortic and tricuspid valves	0.005	0.995	0.000
G59.0 Diabetic mononeuropathy	0.000	0.995	0.005
G90.2 Horner's syndrome	0.005	0.995	0.000
D13.5 Extrahepatic bile ducts	0.005	0.995	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.005	0.995	0.000
G47.9 Sleep disorder, unspecified	0.005	0.995	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.005	0.995	0.000
M25.46 Effusion of joint (Lower leg)	0.000	0.995	0.005
D13.0 Oesophagus	0.005	0.995	0.000
E11.5 With peripheral circulatory complications	0.000	0.995	0.005
I08.9 Multiple valve disease, unspecified	0.005	0.995	0.000
G90.8 Other disorders of autonomic nervous system	0.004	0.995	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.005	0.995	0.000
G90.4 Autonomic dysreflexia	0.004	0.996	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.004	0.996	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.996	0.004
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.004	0.996	0.000
I08.8 Other multiple valve diseases	0.004	0.996	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.004	0.996	0.000
D13.7 Endocrine pancreas	0.004	0.996	0.000
D13.4 Liver	0.004	0.996	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.004	0.996	0.000
I34.0 Mitral (valve) insufficiency	0.004	0.996	0.000
S70.1 Contusion of thigh	0.004	0.996	0.000
L89.2 Stage III decubitus ulcer	0.004	0.996	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.004	0.996	0.000
D13.6 Pancreas	0.004	0.996	0.000
L89.3 Stage IV decubitus ulcer	0.004	0.996	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.004	0.996	0.000
L89 Decubitus ulcer	0.004	0.996	0.000
C76.3 Pelvis	0.003	0.996	0.000
D13.9 Ill-defined sites within the digestive system	0.003	0.996	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.004	0.996	0.000
Y43.3 Other antineoplastic drugs	0.003	0.997	0.000
U88 Agent resistant to multiple antibiotics	0.000	0.997	0.003
C76.0 Head, face and neck	0.003	0.997	0.000
C76.2 Abdomen	0.003	0.997	0.000
R45.8 Other symptoms and signs involving emotional state	0.003	0.997	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.003	0.997	0.000
C76.7 Other ill-defined sites	0.003	0.997	0.000
C76.5 Lower limb	0.003	0.997	0.000
C76.4 Upper limb	0.003	0.997	0.000
Z29 Need for other prophylactic measures	0.003	0.997	0.000
M34.9 Systemic sclerosis, unspecified	0.003	0.997	0.000
Z04.8 Examination and observation for other specified reasons	0.000	0.997	0.003
Z20 Contact with and exposure to communicable diseases	0.003	0.997	0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.003	0.997	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.003	0.997	0.000
Z28 Immunisation not carried out	0.003	0.997	0.000
Z27 Need for immunisation against combinations of infectious diseases	0.003	0.997	0.000
Z26 Need for immunisation against other single infectious diseases	0.003	0.997	0.000
Z25 Need for immunisation against other single viral diseases	0.003	0.997	0.000
Z23 Need for immunisation against single bacterial diseases	0.003	0.997	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.003	0.997	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.997	0.003
Y43.4 Immunosuppressive agents	0.003	0.997	0.000
S62.3 Fracture of other metacarpal bone	0.000	0.997	0.003
C50.5 Lower-outer quadrant of breast	0.000	0.997	0.003
C76.1 Thorax	0.003	0.997	0.000
L89.1 Stage II decubitus ulcer	0.003	0.997	0.000
M47.2 Other spondylosis with radiculopathy	0.003	0.997	0.000
M34.8 Other forms of systemic sclerosis	0.003	0.997	0.000
Z29.0 Isolation	0.003	0.997	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.003	0.997	0.000
Z29.8 Other specified prophylactic measures	0.003	0.997	0.000
Z24 Need for immunisation against certain single viral diseases	0.003	0.997	0.000
Y84.2 Radiological procedure and radiotherapy	0.003	0.997	0.000
Y43 Primarily systemic agents	0.003	0.997	0.000
R76.8 Other specified abnormal immunological findings in serum	0.003	0.997	0.000
M34.1 CR(E)ST syndrome	0.003	0.997	0.000
Z20.1 Contact with and exposure to tuberculosis	0.002	0.997	0.000
M25.71 Osteophyte (Shoulder region)	0.003	0.997	0.000
F43.0 Acute stress reaction	0.000	0.997	0.003
M34 Systemic sclerosis	0.003	0.997	0.000
S62.31 Fracture of other metacarpal bone (open)	0.000	0.997	0.002
D13.2 Duodenum	0.002	0.997	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.003	0.997	0.000
Z29.9 Prophylactic measure, unspecified	0.002	0.997	0.000
I86.4 Gastric varices	0.002	0.998	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.002	0.998	0.000
Y43.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
Z29.2 Other prophylactic chemotherapy	0.002	0.998	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.002	0.998	0.000
Z20.9 Contact with and exposure to unspecified communicable disease	0.002	0.998	0.000
Z20.7 Contact with and exposure to pediculosis, acariasis and other infestations	0.002	0.998	0.000
Z20.6 Contact with and exposure to human immunodeficiency virus [HIV]	0.002	0.998	0.000
Z20.5 Contact with and exposure to viral hepatitis	0.002	0.998	0.000
Z20.4 Contact with and exposure to rubella	0.002	0.998	0.000
Z20.3 Contact with and exposure to rabies	0.002	0.998	0.000
Z20.2 Contact with and exposure to infections with a predominantly sexual mode of transmission	0.002	0.998	0.000
Z20.0 Contact with and exposure to intestinal infectious diseases	0.002	0.998	0.000
C80 Malignant neoplasm without specification of site	0.002	0.998	0.000
O20.0 Threatened abortion	0.000	0.998	0.002
Z23.8 Need for immunisation against other single bacterial diseases	0.002	0.998	0.000
Z23.7 Need for immunisation against pertussis alone	0.002	0.998	0.000
Z23.6 Need for immunisation against diphtheria alone	0.002	0.998	0.000
Z23.5 Need for immunisation against tetanus alone	0.002	0.998	0.000
Z23.4 Need for immunisation against tularaemia	0.002	0.998	0.000
Z23.3 Need for immunisation against plague	0.002	0.998	0.000
Z23.2 Need for immunisation against tuberculosis [BCG]	0.002	0.998	0.000
Z23.1 Need for immunisation against typhoid-paratyphoid alone [TAB]	0.002	0.998	0.000
Z23.0 Need for immunisation against cholera alone	0.002	0.998	0.000
Z25.8 Need for immunisation against other specified single viral diseases	0.002	0.998	0.000
Z25.1 Need for immunisation against influenza	0.002	0.998	0.000
Z25.0 Need for immunisation against mumps alone	0.002	0.998	0.000
Z26.9 Need for immunisation against unspecified infectious disease	0.002	0.998	0.000
Z26.8 Need for immunisation against other specified single infectious diseases	0.002	0.998	0.000
Z26.0 Need for immunisation against leishmaniasis	0.002	0.998	0.000
Z27.9 Need for immunisation against unspecified combinations of infectious diseases	0.002	0.998	0.000
Z27.8 Need for immunisation against other combinations of infectious diseases	0.002	0.998	0.000
Z27.4 Need for immunisation against measles-mumps-rubella [MMR]	0.002	0.998	0.000
Z27.3 Need for immunisation against diphtheria-tetanus-pertussis with poliomyelitis [DTP + polio]	0.002	0.998	0.000
Z27.2 Need for immunisation against diphtheria-tetanus-pertussis with typhoid-paratyphoid [DTP + TAB]	0.002	0.998	0.000
Z27.1 Need for immunisation against diphtheria-tetanus-pertussis, combined [DTP]	0.002	0.998	0.000
Z27.0 Need for immunisation against cholera with typhoid-paratyphoid [cholera + TAB]	0.002	0.998	0.000
Z28.9 Immunisation not carried out for unspecified reason	0.002	0.998	0.000
Z28.8 Immunisation not carried out for other reasons	0.002	0.998	0.000
Z28.2 Immunisation not carried out because of patient's decision for other and unspecified reasons	0.002	0.998	0.000
Z28.1 Immunisation not carried out because of patient's decision for reasons of belief or group pressure	0.002	0.998	0.000
Z28.0 Immunisation not carried out because of contraindication	0.002	0.998	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.002	0.998	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.002	0.998	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.002	0.998	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.002	0.998	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.002	0.998	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.002	0.998	0.000
I86.8 Varicose veins of other specified sites	0.002	0.998	0.000
Z20.8 Contact with and exposure to other communicable diseases	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
H81.2 Vestibular neuronitis	0.002	0.998	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.000	0.998	0.002
Z24.6 Need for immunisation against viral hepatitis	0.002	0.998	0.000
Z24.4 Need for immunisation against measles alone	0.002	0.998	0.000
Z24.3 Need for immunisation against yellow fever	0.002	0.998	0.000
Z24.2 Need for immunisation against rabies	0.002	0.998	0.000
Z24.1 Need for immunisation against arthropod-borne viral encephalitis	0.002	0.998	0.000
Z24.0 Need for immunisation against poliomyelitis	0.002	0.998	0.000
Z43.1 Attention to gastrostomy	0.002	0.998	0.000
Y43.9 Primarily systemic agent, unspecified	0.002	0.998	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.002	0.998	0.000
Y43.6 Enzymes, not elsewhere classified	0.002	0.998	0.000
Y43.5 Acidifying and alkalising agents	0.002	0.998	0.000
Y43.2 Antineoplastic natural products	0.002	0.998	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.002	0.998	0.000
M34.0 Progressive systemic sclerosis	0.002	0.998	0.000
S52.1 Fracture of upper end of radius	0.000	0.998	0.002
C80.9 Malignant neoplasm, unspecified	0.002	0.998	0.000
I86.2 Pelvic varices	0.002	0.998	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.002	0.998	0.000
V89.9 Person injured in unspecified vehicle accident	0.000	0.998	0.002
I86 Varicose veins of other sites	0.002	0.998	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.998	0.002
Y84.6 Urinary catheterisation	0.002	0.998	0.000
R30.0 Dysuria	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
Z24.5 Need for immunisation against rubella alone	0.002	0.998	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.002	0.998	0.000
J03.9 Acute tonsillitis, unspecified	0.002	0.998	0.000
T21.2 Burn of second degree of trunk	0.000	0.998	0.002
Y45.1 Salicylates	0.002	0.998	0.000
S70-S79 Injuries to the hip and thigh	0.002	0.998	0.000
R49.0 Dysphonia	0.002	0.998	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.002	0.998	0.000
G59.8 Other mononeuropathies in diseases classified elsewhere	0.000	0.998	0.002
C83.0 Small cell (diffuse)	0.000	0.998	0.002
I35.9 Aortic valve disorder, unspecified	0.002	0.998	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
O40 Polyhydramnios	0.002	0.998	0.000
S75 Injury of blood vessels at hip and thigh level	0.002	0.998	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.998	0.002
C77.3 Axillary and upper limb lymph nodes	0.002	0.998	0.000
I86.1 Scrotal varices	0.002	0.998	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.000	0.998	0.002
M81.40 Drug-induced osteoporosis (Multiple sites)	0.002	0.998	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.998	0.002
M25.56 Pain in joint (Lower leg)	0.000	0.998	0.002
S75.0 Injury of femoral artery	0.002	0.998	0.000
I86.0 Sublingual varices	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
Y84.9 Medical procedure, unspecified	0.002	0.998	0.000
Z29.1 Prophylactic immunotherapy	0.002	0.998	0.000
S79 Other and unspecified injuries of hip and thigh	0.002	0.998	0.000
U84 Resistance to other antimicrobial drugs	0.000	0.998	0.002
U83 Resistance to other antibiotics	0.000	0.998	0.002
U82 Resistance to betalactam antibiotics	0.000	0.998	0.002
U85 Resistance to antineoplastic drugs	0.000	0.998	0.002
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.998	0.002
N43.3 Hydrocele, unspecified	0.002	0.998	0.000
U89 Agent resistant to other and unspecified antibiotics	0.000	0.998	0.002
I51.0 Cardiac septal defect, acquired	0.002	0.998	0.000
S79.8 Other specified injuries of hip and thigh	0.002	0.998	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
C09.9 Tonsil, unspecified	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
S78 Traumatic amputation of hip and thigh	0.002	0.998	0.000
S77 Crushing injury of hip and thigh	0.002	0.998	0.000
S74 Injury of nerves at hip and thigh level	0.002	0.998	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.998	0.002
S52.11 Fracture of upper end of radius (open)	0.000	0.998	0.001
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.998	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.002	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
G44.2 Tension-type headache	0.000	0.998	0.002
T88.4 Failed or difficult intubation	0.002	0.998	0.000
R14 Flatulence and related conditions	0.002	0.998	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.002	0.998	0.000
R68.8 Other specified general symptoms and signs	0.002	0.998	0.000
I86.3 Vulval varices	0.001	0.998	0.000
Y43.1 Antineoplastic antimetabolites	0.001	0.998	0.000
C04.9 Floor of mouth, unspecified	0.002	0.998	0.000
J86.0 Pyothorax with fistula	0.002	0.998	0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.000	0.998	0.002
M81.4 Drug-induced osteoporosis	0.002	0.998	0.000
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.001	0.998	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.001	0.998	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.001	0.998	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.001	0.998	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.001	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
J98.5 Diseases of mediastinum, not elsewhere classified	0.002	0.998	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.998	0.002
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.000	0.998	0.002
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.998	0.002
E22.0 Acromegaly and pituitary gigantism	0.000	0.998	0.002
H81 Disorders of vestibular function	0.002	0.998	0.000
H81.9 Disorder of vestibular function, unspecified	0.001	0.998	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.001	0.998	0.000
U82.9 Resistance to betalactam antibiotics, unspecified	0.000	0.998	0.001
U82.8 Resistance to other betalactam antibiotics	0.000	0.998	0.001
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.000	0.998	0.001
U82.1 Resistance to methicillin	0.000	0.998	0.001
U82.0 Resistance to penicillin	0.000	0.998	0.001
U83.9 Resistance to unspecified antibiotic	0.000	0.998	0.001
U83.8 Resistance to other single specified antibiotic	0.000	0.998	0.001
U83.7 Resistance to multiple antibiotics	0.000	0.998	0.001
U83.2 Resistance to quinolones	0.000	0.998	0.001
U83.1 Resistance to other vancomycin related antibiotics	0.000	0.998	0.001
U83.0 Resistance to vancomycin	0.000	0.998	0.001
U84.9 Resistance to unspecified antimicrobial drugs	0.000	0.998	0.001
U84.8 Resistance to other specified antimicrobial drug	0.000	0.998	0.001
U84.7 Resistance to multiple antimicrobial drugs	0.000	0.998	0.001
U84.3 Resistance to tuberculostatic drug(s)	0.000	0.998	0.001
U84.2 Resistance to antiviral drug(s)	0.000	0.998	0.001
U84.1 Resistance to antifungal drug(s)	0.000	0.998	0.001
U84.0 Resistance to antiparasitic drug(s)	0.000	0.998	0.001
Z22.3 Carrier of other specified bacterial diseases	0.002	0.998	0.000
K83.0 Cholangitis	0.000	0.998	0.002
S62.2 Fracture of first metacarpal bone	0.000	0.998	0.001
S79.7 Multiple injuries of hip and thigh	0.001	0.998	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.001	0.998	0.000
U89.9 Agent resistant to unspecified antibiotic	0.000	0.998	0.001
O14.9 Preeclampsia, unspecified	0.000	0.998	0.001
H81.1 Benign paroxysmal vertigo	0.001	0.999	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.001	0.999	0.000
S74.8 Injury of other nerves at hip and thigh level	0.001	0.999	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.001	0.999	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.001	0.999	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.001	0.999	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.001	0.999	0.000
S77.2 Crushing injury of hip with thigh	0.001	0.999	0.000
S77.1 Crushing injury of thigh	0.001	0.999	0.000
S77.0 Crushing injury of hip	0.001	0.999	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.001	0.999	0.000
S78.1 Traumatic amputation at level between hip and knee	0.001	0.999	0.000
S78.0 Traumatic amputation at hip joint	0.001	0.999	0.000
Y45.4 Antirheumatics	0.001	0.999	0.000
T21 Burn and corrosion of trunk	0.000	0.999	0.001
N15.9 Renal tubulo-interstitial disease, unspecified	0.001	0.999	0.000
S76.1 Injury of quadriceps muscle and tendon	0.001	0.999	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.001	0.999	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.001	0.999	0.000
S76.0 Injury of muscle and tendon of hip	0.001	0.999	0.000
U89.8 Agent resistant to other single specified antibiotic	0.000	0.999	0.001
S71 Open wound of hip and thigh	0.001	0.999	0.000
H80.9 Otosclerosis, unspecified	0.001	0.999	0.000
L73.2 Hidradenitis suppurativa	0.001	0.999	0.000
M81.48 Drug-induced osteoporosis (Other)	0.001	0.999	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.001	0.999	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.001	0.999	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.001	0.999	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.001	0.999	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.001	0.999	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.001	0.999	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.001	0.999	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.001	0.999	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.001	0.999	0.000
Y46.4 Iminostilbenes	0.001	0.999	0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.001	0.999	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.001	0.999	0.000
H81.4 Vertigo of central origin	0.001	0.999	0.000
N15.1 Renal and perinephric abscess	0.001	0.999	0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.000	0.999	0.001
S71.0 Open wound of hip	0.001	0.999	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.000	0.999	0.001
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.000	0.999	0.001
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.000	0.999	0.001
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.999	0.001
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.000	0.999	0.001
Y44.2 Anticoagulants	0.001	0.999	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.999	0.001
T63.4 Venom of other arthropods	0.000	0.999	0.001
T92.8 Sequelae of other specified injuries of upper limb	0.000	0.999	0.001
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.999	0.001
Z99.1 Dependence on respirator	0.001	0.999	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.999	0.001
M79.79 Fibromyalgia (Site unspecified)	0.001	0.999	0.000
S62.21 Fracture of first metacarpal bone (open)	0.000	0.999	0.001
H72.8 Other perforations of tympanic membrane	0.001	0.999	0.000
M22.2 Patellofemoral disorders	0.001	0.999	0.000
N43.4 Spermatocele	0.001	0.999	0.000
T17.2 Foreign body in pharynx	0.001	0.999	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.000	0.999	0.001
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.001	0.999	0.000
H81.8 Other disorders of vestibular function	0.001	0.999	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.001	0.999	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.999	0.001
O72.2 Delayed and secondary postpartum haemorrhage	0.001	0.999	0.000
S62.1 Fracture of other carpal bone(s)	0.000	0.999	0.001
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.001	0.999	0.000
T21.0 Burn of unspecified degree of trunk	0.000	0.999	0.001
T25.3 Burn of third degree of ankle and foot	0.000	0.999	0.001
M89.09 Algoneurodystrophy (Site unspecified)	0.001	0.999	0.000
F45.9 Somatoform disorder, unspecified	0.001	0.999	0.000
I35.1 Aortic (valve) insufficiency	0.001	0.999	0.000
J98.2 Interstitial emphysema	0.001	0.999	0.000
S79.9 Unspecified injury of hip and thigh	0.001	0.999	0.000
T21.7 Corrosion of third degree of trunk	0.000	0.999	0.001
T21.6 Corrosion of second degree of trunk	0.000	0.999	0.001
T21.5 Corrosion of first degree of trunk	0.000	0.999	0.001
T21.4 Corrosion of unspecified degree of trunk	0.000	0.999	0.001
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.999	0.001
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.999	0.001
Y52.1 Calcium-channel blockers	0.000	0.999	0.001
Y84.4 Aspiration of fluid	0.001	0.999	0.000
J98 Other respiratory disorders	0.001	0.999	0.000
S62 Fracture at wrist and hand level	0.000	0.999	0.001
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.001	0.999	0.000
M89.03 Algoneurodystrophy (Forearm)	0.001	0.999	0.000
S76.10 Unspecified injury of quadriceps muscle, fascia and tendon	0.001	0.999	0.000
G71.1 Myotonic disorders	0.000	0.999	0.001
H74.9 Disorder of middle ear and mastoid, unspecified	0.001	0.999	0.000
H81.3 Other peripheral vertigo	0.001	0.999	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.001	0.999	0.000
S62.4 Multiple fractures of metacarpal bones	0.000	0.999	0.001
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.001	0.999	0.000
S71.7 Multiple open wounds of of hip and thigh	0.001	0.999	0.000
H27.8 Other specified disorders of lens	0.000	0.999	0.001
H74.1 Adhesive middle ear disease	0.001	0.999	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.999	0.001
S73.1 Sprain and strain of hip	0.001	0.999	0.000
T93.0 Sequelae of open wound of lower limb	0.000	0.999	0.001
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.001	0.999	0.000
T25 Burn and corrosion of ankle and foot	0.000	0.999	0.001
M25.53 Pain in joint (Forearm)	0.001	0.999	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.999	0.001
H60.9 Otitis externa, unspecified	0.001	0.999	0.000
N43.1 Infected hydrocele	0.001	0.999	0.000
O87.2 Haemorrhoids in the puerperium	0.001	0.999	0.000
T92.1 Sequelae of fracture of arm	0.000	0.999	0.001
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.001	0.999	0.000
E14.9 Without complications	0.000	0.999	0.001
H49.0 Third [oculomotor] nerve palsy	0.000	0.999	0.001
N60.2 Fibroadenosis of breast	0.001	0.999	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.000	0.999	0.001
M46.46 Discitis, unspecified (Lumbar region)	0.001	0.999	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.001	0.999	0.000
O21.0 Mild hyperemesis gravidarum	0.001	0.999	0.000
T25.2 Burn of second degree of ankle and foot	0.000	0.999	0.001
Y42.5 Other oestrogens and progestogens	0.001	0.999	0.000
Y45.0 Opioids and related analgesics	0.001	0.999	0.000
Y46.7 Anti-Parkinsonism drugs	0.001	0.999	0.000
Y84.7 Blood-sampling	0.001	0.999	0.000
Y84.5 Insertion of gastric or duodenal sound	0.001	0.999	0.000
Y84.3 Shock therapy	0.001	0.999	0.000
H80 Otosclerosis	0.001	0.999	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.001	0.999	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.999	0.001
G47.2 Disorders of the sleep-wake schedule	0.001	0.999	0.000
J86.9 Pyothorax without fistula	0.001	0.999	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.001	0.999	0.000
S73.0 Dislocation of hip	0.001	0.999	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.001	0.999	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.000	0.999	0.001
Y46.6 Other and unspecified antiepileptics	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations