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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3007243
log Bayes Factor = 4.45029
Chromosome 13   position 105,806,954  (GRCh37) Explore rs3007243 on Ensembl!
Variant rs3007243 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
S70-S79 Injuries to the hip and thigh
0.978 0.022 0.000
Chapter VII Diseases of the eye and adnexa
0.977 0.023 0.000
Chapter XI Diseases of the digestive system
0.975 0.025 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.974 0.026 0.000
S00-S09 Injuries to the head
0.972 0.028 0.000
K22 Other diseases of oesophagus
0.970 0.030 0.000
H30-H36 Disorders of choroid and retina
0.967 0.033 0.000
Chapter IX Diseases of the circulatory system
0.967 0.033 0.000
K22.7 Barrett's oesophagus
0.966 0.034 0.000
Chapter XX External causes of morbidity and mortality
0.962 0.038 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.961 0.039 0.000
H33 Retinal detachments and breaks
0.960 0.040 0.000
K22.1 Ulcer of oesophagus
0.957 0.043 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.951 0.049 0.000
Chapter VIII Diseases of the ear and mastoid process
0.951 0.049 0.000
K70-K77 Diseases of liver
0.950 0.050 0.000
S72 Fracture of femur
0.948 0.052 0.000
I74 Arterial embolism and thrombosis
0.942 0.058 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.940 0.060 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.931 0.069 0.000
K70 Alcoholic liver disease
0.927 0.073 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.922 0.078 0.000
S72.0 Fracture of neck of femur
0.916 0.084 0.000
H33.0 Retinal detachment with retinal break
0.913 0.087 0.000
L40-L45 Papulosquamous disorders
0.907 0.093 0.000
H33.2 Serous retinal detachment
0.900 0.100 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.899 0.101 0.000
I73 Other peripheral vascular diseases
0.898 0.102 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.896 0.104 0.000
L40 Psoriasis
0.894 0.106 0.000
E65-E68 Obesity and other hyperalimentation
0.894 0.106 0.000
S72.00 Fracture of neck of femur (closed)
0.894 0.106 0.000
K22.9 Disease of oesophagus, unspecified
0.889 0.111 0.000
H60-H62 Diseases of external ear
0.876 0.124 0.000
I73.9 Peripheral vascular disease, unspecified
0.875 0.125 0.000
T90 Sequelae of injuries of head
0.872 0.128 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.871 0.129 0.000
I74.5 Embolism and thrombosis of iliac artery
0.870 0.130 0.000
K65-K67 Diseases of peritoneum
0.868 0.132 0.000
H65-H75 Diseases of middle ear and mastoid
0.864 0.136 0.000
S20-S29 Injuries to the thorax
0.863 0.137 0.000
S02 Fracture of skull and facial bones
0.862 0.138 0.000
E66 Obesity
0.862 0.138 0.000
S00 Superficial injury of head
0.859 0.141 0.000
L40.5 Arthropathic psoriasis
0.856 0.144 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.852 0.148 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.850 0.150 0.000
S90-S99 Injuries to the ankle and foot
0.845 0.155 0.000
K70.9 Alcoholic liver disease, unspecified
0.843 0.157 0.000
Q80-Q89 Other congenital malformations
0.837 0.163 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.837 0.163 0.000
H33.3 Retinal breaks without detachment
0.837 0.163 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.836 0.164 0.000
E66.9 Obesity, unspecified
0.836 0.164 0.000
S60-S69 Injuries to the wrist and hand
0.835 0.165 0.000
K72 Hepatic failure, not elsewhere classified
0.835 0.165 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.834 0.166 0.000
L40.9 Psoriasis, unspecified
0.825 0.175 0.000
E00-E07 Disorders of thyroid gland
0.823 0.177 0.000
S06 Intracranial injury
0.820 0.179 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.820 0.180 0.000
K40-K46 Hernia
0.819 0.181 0.000
I74.8 Embolism and thrombosis of other arteries
0.818 0.182 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.818 0.182 0.000
S79 Other and unspecified injuries of hip and thigh
0.816 0.184 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.810 0.190 0.000
K70.3 Alcoholic cirrhosis of liver
0.808 0.192 0.000
K22.4 Dyskinesia of oesophagus
0.803 0.197 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.801 0.199 0.000
K65 Peritonitis
0.798 0.202 0.000
H60 Otitis externa
0.798 0.202 0.000
I72 Other aneurysm
0.794 0.206 0.000
H53-H54 Visual disturbances and blindness
0.794 0.206 0.000
K42 Umbilical hernia
0.789 0.211 0.000
H43-H45 Disorders of vitreous body and globe
0.789 0.211 0.000
K27 Peptic ulcer, site unspecified
0.789 0.211 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.787 0.213 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.784 0.216 0.000
I89.0 Lymphoedema, not elsewhere classified
0.781 0.219 0.000
I86 Varicose veins of other sites
0.780 0.220 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.779 0.221 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.778 0.222 0.000
T81 Complications of procedures, not elsewhere classified
0.777 0.223 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.775 0.225 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.771 0.229 0.000
X60-X84 Intentional self-harm
0.770 0.230 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.769 0.231 0.000
K70.4 Alcoholic hepatic failure
0.768 0.232 0.000
S01 Open wound of head
0.767 0.233 0.000
I71 Aortic aneurysm and dissection
0.763 0.237 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.763 0.237 0.000
S10-S19 Injuries to the neck
0.759 0.241 0.000
I95 Hypotension
0.758 0.242 0.000
S00.8 Superficial injury of other parts of head
0.758 0.242 0.000
I85 Oesophageal varices
0.755 0.245 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.754 0.246 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.754 0.246 0.000
T90.4 Sequelae of injury of eye and orbit
0.752 0.248 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.750 0.250 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.749 0.251 0.000
E05.9 Thyrotoxicosis, unspecified
0.748 0.252 0.000
H71 Cholesteatoma of middle ear
0.747 0.253 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.745 0.255 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.743 0.257 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.742 0.258 0.000
Y95 Nosocomial condition
0.742 0.258 0.000
S40-S49 Injuries to the shoulder and upper arm
0.741 0.259 0.000
H10-H13 Disorders of conjunctiva
0.741 0.259 0.000
K13 Other diseases of lip and oral mucosa
0.740 0.260 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.739 0.261 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.739 0.261 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.738 0.262 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.736 0.264 0.000
Q50-Q56 Congenital malformations of genital organs
0.736 0.264 0.000
V80-V89 Other land transport accidents
0.735 0.265 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.734 0.266 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.734 0.266 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.733 0.267 0.000
K09 Cysts of oral region, not elsewhere classified
0.732 0.268 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.730 0.270 0.000
H74 Other disorders of middle ear and mastoid
0.730 0.270 0.000
L50-L54 Urticaria and erythema
0.729 0.271 0.000
K22.8 Other specified diseases of oesophagus
0.728 0.272 0.000
I99 Other and unspecified disorders of circulatory system
0.726 0.274 0.000
Y00-Y09 Assault
0.726 0.274 0.000
Q00-Q07 Congenital malformations of the nervous system
0.726 0.274 0.000
S02.2 Fracture of nasal bones
0.725 0.275 0.000
S72.3 Fracture of shaft of femur
0.724 0.276 0.000
H34 Retinal vascular occlusions
0.722 0.278 0.000
S70 Superficial injury of hip and thigh
0.721 0.279 0.000
I95.9 Hypotension, unspecified
0.720 0.280 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.719 0.281 0.000
E10-E14 Diabetes mellitus
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H36 Retinal disorders in diseases classified elsewhere
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.715 0.285 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.715 0.285 0.000
K70.0 Alcoholic fatty liver
0.714 0.286 0.000
S71 Open wound of hip and thigh
0.714 0.286 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.712 0.288 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.712 0.288 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
T90.9 Sequelae of unspecified injury of head
0.709 0.290 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.291 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.708 0.292 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.708 0.292 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.707 0.293 0.000
H61 Other disorders of external ear
0.706 0.294 0.000
S72.4 Fracture of lower end of femur
0.705 0.294 0.000
I81 Portal vein thrombosis
0.704 0.295 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.704 0.296 0.000
H31 Other disorders of choroid
0.704 0.296 0.000
S00.1 Contusion of eyelid and periocular area
0.704 0.296 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.702 0.298 0.000
S64 Injury of nerves at wrist and hand level
0.701 0.298 0.000
S78 Traumatic amputation of hip and thigh
0.701 0.299 0.000
S77 Crushing injury of hip and thigh
0.701 0.299 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.701 0.299 0.000
S75 Injury of blood vessels at hip and thigh level
0.701 0.299 0.000
S74 Injury of nerves at hip and thigh level
0.701 0.299 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.701 0.299 0.000
K65.0 Acute peritonitis
0.701 0.299 0.000
S79.9 Unspecified injury of hip and thigh
0.700 0.300 0.000
K70.1 Alcoholic hepatitis
0.699 0.301 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.698 0.302 0.000
Q35-Q37 Cleft lip and cleft palate
0.698 0.302 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.698 0.302 0.000
K72.0 Acute and subacute hepatic failure
0.698 0.302 0.000
K44 Diaphragmatic hernia
0.698 0.302 0.000
S08 Traumatic amputation of part of head
0.697 0.303 0.000
S07 Crushing injury of head
0.697 0.303 0.000
S04 Injury of cranial nerves
0.697 0.303 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.697 0.303 0.000
E40-E46 Malnutrition
0.696 0.303 0.000
H69 Other disorders of Eustachian tube
0.696 0.304 0.000
S72.1 Pertrochanteric fracture
0.696 0.304 0.000
H73 Other disorders of tympanic membrane
0.696 0.304 0.000
K22.3 Perforation of oesophagus
0.695 0.305 0.000
K73 Chronic hepatitis, not elsewhere classified
0.695 0.305 0.000
S80-S89 Injuries to the knee and lower leg
0.695 0.305 0.000
T66-T78 Other and unspecified effects of external causes
0.694 0.306 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.693 0.306 0.000
H30 Chorioretinal inflammation
0.693 0.306 0.000
I00-I02 Acute rheumatic fever
0.693 0.306 0.000
K76 Other diseases of liver
0.693 0.307 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.693 0.307 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.693 0.307 0.000
K72.9 Hepatic failure, unspecified
0.692 0.308 0.000
S72.2 Subtrochanteric fracture
0.690 0.310 0.000
Y35-Y36 Legal intervention and operations of war
0.690 0.310 0.000
Y10-Y34 Event of undetermined intent
0.690 0.310 0.000
X85-X99 Assault
0.690 0.310 0.000
X50-X57 Overexertion, travel and privation
0.690 0.310 0.000
X30-X39 Exposure to forces of nature
0.690 0.310 0.000
X10-X19 Contact with heat and hot substances
0.690 0.310 0.000
X00-X09 Exposure to smoke, fire and flames
0.690 0.310 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.690 0.310 0.000
W75-W84 Other accidental threats to breathing
0.690 0.310 0.000
W65-W74 Accidental drowning and submersion
0.690 0.310 0.000
W50-W64 Exposure to animate mechanical forces
0.690 0.310 0.000
V98-V99 Other and unspecified transport accidents
0.690 0.310 0.000
V95-V97 Air and space transport accidents
0.690 0.310 0.000
V90-V94 Water transport accidents
0.690 0.310 0.000
V70-V79 Bus occupant injured in transport accident
0.690 0.310 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.690 0.310 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.690 0.310 0.000
V40-V49 Car occupant injured in transport accident
0.690 0.310 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.690 0.310 0.000
V01-V09 Pedestrian injured in transport accident
0.690 0.310 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.690 0.310 0.000
H60.9 Otitis externa, unspecified
0.688 0.312 0.000
H33.4 Traction detachment of retina
0.688 0.312 0.000
H33.1 Retinoschisis and retinal cysts
0.688 0.312 0.000
X20-X29 Contact with venomous animals and plants
0.686 0.314 0.000
T93 Sequelae of injuries of lower limb
0.684 0.316 0.000
K09.0 Developmental odontogenic cysts
0.684 0.316 0.000
S05 Injury of eye and orbit
0.684 0.316 0.000
L43 Lichen planus
0.683 0.317 0.000
K28 Gastrojejunal ulcer
0.682 0.318 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.682 0.318 0.000
S62 Fracture at wrist and hand level
0.681 0.319 0.000
V10-V19 Pedal cyclist injured in transport accident
0.681 0.319 0.000
K77 Liver disorders in diseases classified elsewhere
0.681 0.319 0.000
K71 Toxic liver disease
0.681 0.319 0.000
Chapter XXII Codes for special purposes
0.681 0.319 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.680 0.320 0.000
S72.9 Fracture of femur, part unspecified
0.680 0.320 0.000
S72.8 Fractures of other parts of femur
0.680 0.320 0.000
S72.7 Multiple fractures of femur
0.680 0.320 0.000
Q82 Other congenital malformations of skin
0.680 0.320 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.679 0.321 0.000
W20-W49 Exposure to inanimate mechanical forces
0.678 0.322 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.677 0.323 0.000
E07 Other disorders of thyroid
0.676 0.323 0.000
I60-I69 Cerebrovascular diseases
0.676 0.324 0.000
H90-H95 Other disorders of ear
0.676 0.324 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.675 0.324 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.675 0.324 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.675 0.324 0.000
L20-L30 Dermatitis and eczema
0.675 0.325 0.000
S92 Fracture of foot, except ankle
0.673 0.327 0.000
E66.0 Obesity due to excess calories
0.673 0.327 0.000
E50-E64 Other nutritional deficiencies
0.673 0.327 0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.672 0.328 0.000
L40.0 Psoriasis vulgaris
0.672 0.328 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.672 0.328 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.669 0.331 0.000
H60.8 Other otitis externa
0.668 0.332 0.000
Q43 Other congenital malformations of intestine
0.668 0.332 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.668 0.332 0.000
K65.9 Peritonitis, unspecified
0.668 0.332 0.000
T98 Sequelae of other and unspecified effects of external causes
0.667 0.333 0.000
T95 Sequelae of burns, corrosions and frostbite
0.667 0.333 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.667 0.333 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.667 0.333 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.667 0.333 0.000
H43 Disorders of vitreous body
0.666 0.334 0.000
K22.0 Achalasia of cardia
0.666 0.334 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.665 0.335 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.665 0.335 0.000
I72.8 Aneurysm of other specified arteries
0.665 0.335 0.000
H54 Blindness and low vision
0.664 0.336 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.663 0.337 0.000
S02.1 Fracture of base of skull
0.663 0.337 0.000
S01.8 Open wound of other parts of head
0.662 0.338 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.662 0.338 0.000
L10-L14 Bullous disorders
0.661 0.339 0.000
S02.3 Fracture of orbital floor
0.660 0.340 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.660 0.340 0.000
H70 Mastoiditis and related conditions
0.659 0.341 0.000
S91 Open wound of ankle and foot
0.659 0.341 0.000
H46 Optic neuritis
0.659 0.341 0.000
H40-H42 Glaucoma
0.657 0.343 0.000
S72.01 Fracture of neck of femur (open)
0.657 0.343 0.000
D60-D64 Aplastic and other anaemias
0.657 0.343 0.000
V20-V29 Motorcycle rider injured in transport accident
0.656 0.344 0.000
I83 Varicose veins of lower extremities
0.654 0.346 0.000
E20-E35 Disorders of other endocrine glands
0.654 0.346 0.000
Q60-Q64 Congenital malformations of the urinary system
0.653 0.347 0.000
T91 Sequelae of injuries of neck and trunk
0.652 0.348 0.000
H35 Other retinal disorders
0.651 0.349 0.000
T23 Burn and corrosion of wrist and hand
0.651 0.349 0.000
Y86 Sequelae of other accidents
0.650 0.349 0.000
S02.4 Fracture of malar and maxillary bones
0.650 0.350 0.000
I87 Other disorders of veins
0.650 0.350 0.000
L44 Other papulosquamous disorders
0.650 0.350 0.000
L41 Parapsoriasis
0.650 0.350 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.650 0.350 0.000
L42 Pityriasis rosea
0.650 0.350 0.000
S27 Injury of other and unspecified intrathoracic organs
0.650 0.350 0.000
Chapter V Mental and behavioural disorders
0.649 0.351 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.649 0.351 0.000
H33.5 Other retinal detachments
0.648 0.352 0.000
Q76 Congenital malformations of spine and bony thorax
0.646 0.354 0.000
I88 Nonspecific lymphadenitis
0.645 0.355 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.645 0.355 0.000
I73.8 Other specified peripheral vascular diseases
0.644 0.356 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.644 0.356 0.000
T20 Burn and corrosion of head and neck
0.644 0.356 0.000
I82 Other venous embolism and thrombosis
0.643 0.357 0.000
D66 Hereditary factor VIII deficiency
0.642 0.358 0.000
I86.4 Gastric varices
0.642 0.358 0.000
K46 Unspecified abdominal hernia
0.642 0.358 0.000
Y84.8 Other medical procedures
0.642 0.358 0.000
S22.4 Multiple fractures of ribs
0.641 0.359 0.000
L40.8 Other psoriasis
0.641 0.359 0.000
L40.4 Guttate psoriasis
0.641 0.359 0.000
L40.3 Pustulosis palmaris et plantaris
0.641 0.359 0.000
L40.2 Acrodermatitis continua
0.641 0.359 0.000
L40.1 Generalised pustular psoriasis
0.641 0.359 0.000
E67 Other hyperalimentation
0.641 0.359 0.000
E68 Sequelae of hyperalimentation
0.641 0.359 0.000
E65 Localised adiposity
0.641 0.359 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.641 0.359 0.000
S00.7 Multiple superficial injuries of head
0.641 0.359 0.000
S03.2 Dislocation of tooth
0.639 0.361 0.000
E14 Unspecified diabetes mellitus
0.637 0.363 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.637 0.363 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.636 0.364 0.000
T90.5 Sequelae of intracranial injury
0.635 0.365 0.000
S02.6 Fracture of mandible
0.635 0.365 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.635 0.365 0.000
H74.4 Polyp of middle ear
0.634 0.366 0.000
I85.9 Oesophageal varices without bleeding
0.634 0.366 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.634 0.366 0.000
K76.6 Portal hypertension
0.633 0.367 0.000
S67 Crushing injury of wrist and hand
0.632 0.368 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.632 0.368 0.000
T92 Sequelae of injuries of upper limb
0.631 0.369 0.000
S31 Open wound of abdomen, lower back and pelvis
0.631 0.369 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.630 0.370 0.000
S29 Other and unspecified injuries of thorax
0.629 0.371 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.628 0.372 0.000
S06.3 Focal brain injury
0.628 0.372 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.628 0.372 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.628 0.372 0.000
S01.9 Open wound of head, part unspecified
0.628 0.372 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.627 0.373 0.000
S02.20 Fracture of nasal bones (closed)
0.627 0.373 0.000
Chapter I Certain infectious and parasitic diseases
0.626 0.374 0.000
T90.8 Sequelae of other specified injuries of head
0.625 0.375 0.000
T90.3 Sequelae of injury of cranial nerves
0.625 0.375 0.000
T90.1 Sequelae of open wound of head
0.625 0.375 0.000
T90.0 Sequelae of superficial injury of head
0.625 0.375 0.000
K75 Other inflammatory liver diseases
0.625 0.375 0.000
S01.3 Open wound of ear
0.625 0.375 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.625 0.375 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.625 0.375 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.625 0.375 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.625 0.375 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.625 0.375 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.625 0.375 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.625 0.375 0.000
T36 Poisoning by systemic antibiotics
0.625 0.375 0.000
S00.9 Superficial injury of head, part unspecified
0.624 0.375 0.000
S06.2 Diffuse brain injury
0.624 0.375 0.000
W00-W19 Falls
0.623 0.377 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.622 0.378 0.000
D80-D89 Certain disorders involving the immune mechanism
0.620 0.380 0.000
S20 Superficial injury of thorax
0.620 0.380 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.620 0.380 0.000
H68 Eustachian salpingitis and obstruction
0.620 0.380 0.000
H67 Otitis media in diseases classified elsewhere
0.620 0.380 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.620 0.380 0.000
S02.8 Fractures of other skull and facial bones
0.619 0.381 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.619 0.381 0.000
S26 Injury of heart
0.619 0.381 0.000
S25 Injury of blood vessels of thorax
0.619 0.381 0.000
S24 Injury of nerves and spinal cord at thorax level
0.619 0.381 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.619 0.381 0.000
S21 Open wound of thorax
0.619 0.381 0.000
Y84.6 Urinary catheterisation
0.619 0.381 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.619 0.381 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.618 0.382 0.000
S64.4 Injury of digital nerve of other finger
0.618 0.382 0.000
S02.7 Multiple fractures involving skull and facial bones
0.618 0.382 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.618 0.382 0.000
E66.1 Drug-induced obesity
0.618 0.382 0.000
D55-D59 Haemolytic anaemias
0.617 0.382 0.000
Q65 Congenital deformities of hip
0.617 0.383 0.000
T82.3 Mechanical complication of other vascular grafts
0.616 0.384 0.000
Q79.8 Other congenital malformations of musculoskeletal system
0.616 0.384 0.000
S00.5 Superficial injury of lip and oral cavity
0.616 0.384 0.000
S00.4 Superficial injury of ear
0.616 0.384 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.616 0.384 0.000
Q27 Other congenital malformations of peripheral vascular system
0.615 0.385 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.615 0.385 0.000
Q79.6 Ehlers-Danlos syndrome
0.614 0.386 0.000
L50 Urticaria
0.614 0.386 0.000
T87 Complications peculiar to reattachment and amputation
0.611 0.389 0.000
I86.1 Scrotal varices
0.610 0.390 0.000
Q78 Other osteochondrodysplasias
0.609 0.390 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.609 0.390 0.000
Q75 Other congenital malformations of skull and face bones
0.609 0.390 0.000
Q74 Other congenital malformations of limb(s)
0.609 0.390 0.000
Q73 Reduction defects of unspecified limb
0.609 0.390 0.000
Q72 Reduction defects of lower limb
0.609 0.390 0.000
Q71 Reduction defects of upper limb
0.609 0.390 0.000
Q70 Syndactyly
0.609 0.390 0.000
Q69 Polydactyly
0.609 0.390 0.000
Q68 Other congenital musculoskeletal deformities
0.609 0.390 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.609 0.390 0.000
Q66 Congenital deformities of feet
0.609 0.390 0.000
Q44.6 Cystic disease of liver
0.609 0.390 0.000
K22.2 Oesophageal obstruction
0.609 0.391 0.000
I80 Phlebitis and thrombophlebitis
0.609 0.391 0.000
I05-I09 Chronic rheumatic heart diseases
0.608 0.391 0.000
K09.2 Other cysts of jaw
0.608 0.392 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.607 0.393 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.606 0.394 0.000
S99 Other and unspecified injuries of ankle and foot
0.606 0.394 0.000
S98 Traumatic amputation of ankle and foot
0.606 0.394 0.000
S97 Crushing injury of ankle and foot
0.606 0.394 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.606 0.394 0.000
S95 Injury of blood vessels at ankle and foot level
0.606 0.394 0.000
S94 Injury of nerves at ankle and foot level
0.606 0.394 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.606 0.394 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.605 0.395 0.000
T42.4 Benzodiazepines
0.605 0.395 0.000
S06.0 Concussion
0.605 0.395 0.000
I86.8 Varicose veins of other specified sites
0.604 0.396 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.603 0.397 0.000
S00.0 Superficial injury of scalp
0.603 0.397 0.000
I70 Atherosclerosis
0.602 0.398 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.602 0.398 0.000
S06.8 Other intracranial injuries
0.601 0.399 0.000
Q89 Other congenital malformations, not elsewhere classified
0.600 0.400 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.600 0.400 0.000
Q84 Other congenital malformations of integument
0.600 0.400 0.000
Q83 Congenital malformations of breast
0.600 0.400 0.000
Q81 Epidermolysis bullosa
0.600 0.400 0.000
Q80 Congenital ichthyosis
0.600 0.400 0.000
Q45 Other congenital malformations of digestive system
0.600 0.400 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.600 0.400 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.600 0.400 0.000
Q40 Other congenital malformations of upper alimentary tract
0.600 0.400 0.000
Q39 Congenital malformations of oesophagus
0.600 0.400 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.600 0.400 0.000
I89.1 Lymphangitis
0.600 0.400 0.000
S65 Injury of blood vessels at wrist and hand level
0.599 0.401 0.000
K72.1 Chronic hepatic failure
0.598 0.402 0.000
K66 Other disorders of peritoneum
0.598 0.402 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.598 0.402 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.598 0.402 0.000
Y98 Lifestyle-related condition
0.598 0.402 0.000
Y97 Environmental-pollution-related condition
0.598 0.402 0.000
Y96 Work-related condition
0.598 0.402 0.000
Q21 Congenital malformations of cardiac septa
0.598 0.402 0.000
K65.8 Other peritonitis
0.597 0.403 0.000
Q87.4 Marfan's syndrome
0.596 0.404 0.000
H60.1 Cellulitis of external ear
0.596 0.404 0.000
H61.3 Acquired stenosis of external ear canal
0.595 0.405 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.594 0.406 0.000
D62 Acute posthaemorrhagic anaemia
0.594 0.406 0.000
Y88 Sequelae of surgical and medical care as external cause
0.593 0.406 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.593 0.407 0.000
K76.9 Liver disease, unspecified
0.593 0.407 0.000
S02.0 Fracture of vault of skull
0.592 0.408 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.592 0.408 0.000
T94.1 Sequelae of injuries, not specified by body region
0.591 0.408 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.591 0.409 0.000
S06.5 Traumatic subdural haemorrhage
0.591 0.409 0.000
H34.8 Other retinal vascular occlusions
0.590 0.410 0.000
S22.2 Fracture of sternum
0.590 0.410 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.590 0.410 0.000
E00 Congenital iodine-deficiency syndrome
0.590 0.410 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.590 0.410 0.000
S42 Fracture of shoulder and upper arm
0.590 0.410 0.000
S06.9 Intracranial injury, unspecified
0.588 0.412 0.000
S06.7 Intracranial injury with prolonged coma
0.588 0.412 0.000
S06.4 Epidural haemorrhage
0.588 0.412 0.000
S06.1 Traumatic cerebral oedema
0.588 0.412 0.000
T25 Burn and corrosion of ankle and foot
0.588 0.412 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.588 0.412 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.588 0.412 0.000
T21 Burn and corrosion of trunk
0.588 0.412 0.000
S12 Fracture of neck
0.588 0.412 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.588 0.412 0.000
Q85 Phakomatoses, not elsewhere classified
0.588 0.412 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.588 0.412 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.587 0.413 0.000
F10.2 Dependence syndrome
0.587 0.413 0.000
S79.8 Other specified injuries of hip and thigh
0.585 0.415 0.000
S79.7 Multiple injuries of hip and thigh
0.585 0.415 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.585 0.415 0.000
I72.4 Aneurysm of artery of lower extremity
0.584 0.416 0.000
S09 Other and unspecified injuries of head
0.582 0.418 0.000
S02.5 Fracture of tooth
0.581 0.419 0.000
H66 Suppurative and unspecified otitis media
0.581 0.419 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.581 0.419 0.000
I60 Subarachnoid haemorrhage
0.581 0.419 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.581 0.419 0.000
K83 Other diseases of biliary tract
0.580 0.420 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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