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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3025643
log Bayes Factor = 31.5586
Chromosome 6   position 29,569,955  (GRCh37) Explore rs3025643 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.394 0.606
E10.3 With ophthalmic complications
0.000 0.404 0.596
E10.9 Without complications
0.000 0.433 0.567
E10.4 With neurological complications
0.000 0.446 0.554
E10.2 With renal complications
0.000 0.448 0.552
E10.1 With ketoacidosis
0.000 0.486 0.514
E10.6 With other specified complications
0.000 0.487 0.513
E10.0 With coma
0.000 0.502 0.498
E10-E14 Diabetes mellitus
0.000 0.525 0.475
E13 Other specified diabetes mellitus
0.000 0.548 0.452
E10.7 With multiple complications
0.000 0.555 0.445
E13.9 Without complications
0.000 0.563 0.437
E10.5 With peripheral circulatory complications
0.000 0.573 0.427
K90 Intestinal malabsorption
0.000 0.613 0.387
E12 Malnutrition-related diabetes mellitus
0.000 0.659 0.341
E14 Unspecified diabetes mellitus
0.000 0.672 0.328
E13.8 With unspecified complications
0.000 0.675 0.324
E13.7 With multiple complications
0.000 0.675 0.324
E13.6 With other specified complications
0.000 0.675 0.324
E13.5 With peripheral circulatory complications
0.000 0.675 0.324
E13.4 With neurological complications
0.000 0.675 0.324
E13.3 With ophthalmic complications
0.000 0.675 0.324
E13.2 With renal complications
0.000 0.675 0.324
E13.1 With ketoacidosis
0.000 0.675 0.324
E13.0 With coma
0.000 0.675 0.324
E10.8 With unspecified complications
0.000 0.676 0.323
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.691 0.309
K90.8 Other intestinal malabsorption
0.000 0.722 0.278
K90.3 Pancreatic steatorrhoea
0.000 0.722 0.278
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.722 0.278
K90.1 Tropical sprue
0.000 0.722 0.278
E11 Non-insulin-dependent diabetes mellitus
0.000 0.733 0.267
E14.1 With ketoacidosis
0.000 0.751 0.249
E14.6 With other specified complications
0.000 0.752 0.248
E12.9 Without complications
0.000 0.755 0.244
E12.8 With unspecified complications
0.000 0.755 0.244
E12.7 With multiple complications
0.000 0.755 0.244
E12.6 With other specified complications
0.000 0.755 0.244
E12.5 With peripheral circulatory complications
0.000 0.755 0.244
E12.4 With neurological complications
0.000 0.755 0.244
E12.3 With ophthalmic complications
0.000 0.755 0.244
E12.2 With renal complications
0.000 0.755 0.244
E12.1 With ketoacidosis
0.000 0.755 0.244
E12.0 With coma
0.000 0.755 0.244
E14.8 With unspecified complications
0.000 0.764 0.236
E11.6 With other specified complications
0.000 0.764 0.236
E14.7 With multiple complications
0.000 0.765 0.235
E14.5 With peripheral circulatory complications
0.000 0.765 0.235
E14.0 With coma
0.000 0.765 0.235
E11.1 With ketoacidosis
0.000 0.766 0.234
E14.2 Withrenal complications
0.000 0.769 0.231
E14.3 With ophthalmic complications
0.000 0.770 0.230
E14.4 With neurological complications
0.000 0.773 0.227
E11.0 With coma
0.000 0.780 0.220
E14.9 Without complications
0.000 0.792 0.208
E11.2 With renal complications
0.000 0.796 0.204
K90.9 Intestinal malabsorption, unspecified
0.000 0.799 0.201
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.195 0.805 0.000
E11.8 With unspecified complications
0.000 0.806 0.194
E11.7 With multiple complications
0.000 0.808 0.192
E11.5 With peripheral circulatory complications
0.000 0.811 0.189
E83 Disorders of mineral metabolism
0.184 0.816 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.848 0.152
E23 Hypofunction and other disorders of pituitary gland
0.000 0.860 0.140
E20-E35 Disorders of other endocrine glands
0.000 0.860 0.140
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.862 0.138
E83.4 Disorders of magnesium metabolism
0.136 0.864 0.000
E23.0 Hypopituitarism
0.000 0.866 0.134
E83.9 Disorder of mineral metabolism, unspecified
0.132 0.868 0.000
E83.8 Other disorders of mineral metabolism
0.132 0.868 0.000
E83.2 Disorders of zinc metabolism
0.132 0.868 0.000
E83.0 Disorders of copper metabolism
0.132 0.868 0.000
E24 Cushing's syndrome
0.000 0.869 0.131
K51 Ulcerative colitis
0.131 0.869 0.000
K51.9 Ulcerative colitis, unspecified
0.130 0.870 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.871 0.129
K51.4 Pseudopolyposis of colon
0.126 0.874 0.000
E23.2 Diabetes insipidus
0.000 0.874 0.126
E16.2 Hypoglycaemia, unspecified
0.000 0.877 0.123
E24.9 Cushing's syndrome, unspecified
0.000 0.881 0.119
K51.5 Mucosal proctocolitis
0.117 0.883 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.884 0.116
E83.3 Disorders of phosphorus metabolism
0.115 0.885 0.000
K51.8 Other ulcerative colitis
0.115 0.885 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.888 0.112
K51.2 Ulcerative (chronic) proctitis
0.112 0.888 0.000
E16.1 Other hypoglycaemia
0.000 0.893 0.107
E25 Adrenogenital disorders
0.000 0.894 0.106
K51.3 Ulcerative (chronic) rectosigmoiditis
0.105 0.895 0.000
E00-E07 Disorders of thyroid gland
0.000 0.896 0.104
E23.6 Other disorders of pituitary gland
0.000 0.896 0.104
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.898 0.102
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.899 0.101
E23.1 Drug-induced hypopituitarism
0.000 0.899 0.101
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.900 0.100
E32 Diseases of thymus
0.000 0.900 0.100
E30 Disorders of puberty, not elsewhere classified
0.000 0.900 0.100
E50-E64 Other nutritional deficiencies
0.000 0.900 0.100
E15 Nondiabetic hypoglycaemic coma
0.000 0.900 0.099
E05.9 Thyrotoxicosis, unspecified
0.000 0.901 0.099
E20 Hypoparathyroidism
0.000 0.901 0.099
E24.2 Drug-induced Cushing's syndrome
0.000 0.903 0.097
E34 Other endocrine disorders
0.000 0.905 0.095
E24.8 Other Cushing's syndrome
0.000 0.905 0.094
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.905 0.094
E24.3 Ectopic ACTH syndrome
0.000 0.905 0.094
E24.1 Nelson's syndrome
0.000 0.905 0.094
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.907 0.093
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.907 0.093
E16.4 Abnormal secretion of gastrin
0.000 0.907 0.093
E16.3 Increased secretion of glucagon
0.000 0.907 0.093
E26 Hyperaldosteronism
0.000 0.907 0.093
E31 Polyglandular dysfunction
0.000 0.908 0.092
K51.1 Ulcerative (chronic) ileocolitis
0.091 0.909 0.000
E29 Testicular dysfunction
0.000 0.911 0.089
I83 Varicose veins of lower extremities
0.089 0.911 0.000
E40-E46 Malnutrition
0.000 0.912 0.088
E05.8 Other thyrotoxicosis
0.000 0.913 0.087
K51.0 Ulcerative (chronic) enterocolitis
0.087 0.913 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.915 0.085
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.919 0.081
E61 Deficiency of other nutrient elements
0.000 0.920 0.080
E11.4 With neurological complications
0.000 0.920 0.080
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.924 0.076
E25.9 Adrenogenital disorder, unspecified
0.000 0.924 0.076
E25.8 Other adrenogenital disorders
0.000 0.924 0.076
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.075 0.925 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.925 0.075
E00 Congenital iodine-deficiency syndrome
0.000 0.925 0.075
E27 Other disorders of adrenal gland
0.000 0.926 0.074
E34.9 Endocrine disorder, unspecified
0.000 0.926 0.074
E05.5 Thyroid crisis or storm
0.000 0.926 0.073
E05.4 Thyrotoxicosis factitia
0.000 0.926 0.073
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.926 0.073
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.926 0.073
E28 Ovarian dysfunction
0.000 0.927 0.073
E56 Other vitamin deficiencies
0.000 0.927 0.073
E51 Thiamine deficiency
0.000 0.927 0.073
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.927 0.072
E30.9 Disorder of puberty, unspecified
0.000 0.928 0.072
E30.8 Other disorders of puberty
0.000 0.928 0.072
E30.1 Precocious puberty
0.000 0.928 0.072
E30.0 Delayed puberty
0.000 0.928 0.072
E32.9 Disease of thymus, unspecified
0.000 0.928 0.072
E32.8 Other diseases of thymus
0.000 0.928 0.072
E32.1 Abscess of thymus
0.000 0.928 0.072
E32.0 Persistent hyperplasia of thymus
0.000 0.928 0.072
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.928 0.072
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.928 0.072
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.928 0.072
E34.8 Other specified endocrine disorders
0.000 0.928 0.072
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.928 0.072
E63 Other nutritional deficiencies
0.000 0.928 0.072
E50 Vitamin A deficiency
0.000 0.928 0.072
E60 Dietary zinc deficiency
0.000 0.928 0.072
E59 Dietary selenium deficiency
0.000 0.928 0.072
E54 Ascorbic acid deficiency
0.000 0.928 0.072
E52 Niacin deficiency [pellagra]
0.000 0.928 0.072
E20.8 Other hypoparathyroidism
0.000 0.929 0.071
E20.1 Pseudohypoparathyroidism
0.000 0.929 0.071
E20.0 Idiopathic hypoparathyroidism
0.000 0.929 0.071
E20.9 Hypoparathyroidism, unspecified
0.000 0.930 0.069
E55 Vitamin D deficiency
0.000 0.931 0.069
E61.1 Iron deficiency
0.000 0.931 0.069
E34.5 Androgen resistance syndrome
0.000 0.931 0.068
E34.4 Constitutional tall stature
0.000 0.931 0.068
E34.3 Short stature, not elsewhere classified
0.000 0.931 0.068
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.931 0.068
E34.1 Other hypersecretion of intestinal hormones
0.000 0.931 0.068
E22 Hyperfunction of pituitary gland
0.000 0.931 0.069
E26.9 Hyperaldosteronism, unspecified
0.000 0.933 0.067
E26.8 Other hyperaldosteronism
0.000 0.933 0.067
E26.1 Secondary hyperaldosteronism
0.000 0.933 0.067
E31.9 Polyglandular dysfunction, unspecified
0.000 0.934 0.066
E31.8 Other polyglandular dysfunction
0.000 0.934 0.066
E31.1 Polyglandular hyperfunction
0.000 0.934 0.066
E11.3 With ophthalmic complications
0.000 0.935 0.065
E29.9 Testicular dysfunction, unspecified
0.000 0.936 0.064
E29.8 Other testicular dysfunction
0.000 0.936 0.064
E29.0 Testicular hyperfunction
0.000 0.936 0.064
E06 Thyroiditis
0.000 0.936 0.063
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.937 0.063
E45 Retarded development following protein-energy malnutrition
0.000 0.937 0.063
E43 Unspecified severe protein-energy malnutrition
0.000 0.937 0.063
E42 Marasmic kwashiorkor
0.000 0.937 0.063
E41 Nutritional marasmus
0.000 0.937 0.063
E40 Kwashiorkor
0.000 0.937 0.063
H40.2 Primary angle-closure glaucoma
0.063 0.937 0.000
E58 Dietary calcium deficiency
0.000 0.938 0.062
E03 Other hypothyroidism
0.000 0.938 0.062
E53 Deficiency of other B group vitamins
0.000 0.940 0.060
E26.0 Primary hyperaldosteronism
0.000 0.941 0.059
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.941 0.059
I83.0 Varicose veins of lower extremities with ulcer
0.059 0.941 0.000
E31.0 Autoimmune polyglandular failure
0.000 0.942 0.058
E61.9 Deficiency of nutrient element, unspecified
0.000 0.942 0.058
E61.8 Deficiency of other specified nutrient elements
0.000 0.942 0.058
E61.7 Deficiency of multiple nutrient elements
0.000 0.942 0.058
E61.6 Vanadium deficiency
0.000 0.942 0.058
E61.5 Molybdenum deficiency
0.000 0.942 0.058
E61.4 Chromium deficiency
0.000 0.942 0.058
E61.3 Manganese deficiency
0.000 0.942 0.058
E61.0 Copper deficiency
0.000 0.942 0.058
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.943 0.057
E27.9 Disorder of adrenal gland, unspecified
0.000 0.944 0.056
I83.1 Varicose veins of lower extremities with inflammation
0.056 0.944 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.944 0.056
E03.8 Other specified hypothyroidism
0.000 0.945 0.055
E56.1 Deficiency of vitamin K
0.000 0.946 0.054
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.946 0.054
H40 Glaucoma
0.054 0.946 0.000
E07 Other disorders of thyroid
0.000 0.946 0.054
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.946 0.054
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.946 0.054
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.946 0.054
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.946 0.054
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.946 0.054
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.946 0.054
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.946 0.054
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.946 0.054
E51.2 Wernicke's encephalopathy
0.000 0.946 0.053
E27.5 Adrenomedullary hyperfunction
0.000 0.947 0.053
E27.0 Other adrenocortical overactivity
0.000 0.947 0.053
E06.9 Thyroiditis, unspecified
0.000 0.947 0.053
E29.1 Testicular hypofunction
0.000 0.947 0.053
E28.9 Ovarian dysfunction, unspecified
0.000 0.947 0.053
E28.8 Other ovarian dysfunction
0.000 0.947 0.053
E28.1 Androgen excess
0.000 0.947 0.053
E28.0 Oestrogen excess
0.000 0.947 0.053
E56.9 Vitamin deficiency, unspecified
0.000 0.947 0.053
E56.8 Deficiency of other vitamins
0.000 0.947 0.053
E56.0 Deficiency of vitamin E
0.000 0.947 0.053
H40.5 Glaucoma secondary to other eye disorders
0.053 0.947 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.947 0.053
E51.9 Thiamine deficiency, unspecified
0.000 0.947 0.052
E51.8 Other manifestations of thiamine deficiency
0.000 0.947 0.052
E51.1 Beriberi
0.000 0.947 0.052
E28.3 Primary ovarian failure
0.000 0.948 0.052
E61.2 Magnesium deficiency
0.000 0.948 0.052
E50.9 Vitamin A deficiency, unspecified
0.000 0.948 0.051
E50.8 Other manifestations of vitamin A deficiency
0.000 0.948 0.051
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.948 0.051
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.948 0.051
E50.5 Vitamin A deficiency with night blindness
0.000 0.948 0.051
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.948 0.051
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.948 0.051
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.948 0.051
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.948 0.051
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.948 0.051
E63.9 Nutritional deficiency, unspecified
0.000 0.948 0.051
E63.8 Other specified nutritional deficiencies
0.000 0.948 0.051
E63.1 Imbalance of constituents of food intake
0.000 0.948 0.051
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.948 0.051
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.948 0.051
E64.8 Sequelae of other nutritional deficiencies
0.000 0.948 0.051
E64.3 Sequelae of rickets
0.000 0.948 0.051
E64.2 Sequelae of vitamin C deficiency
0.000 0.948 0.051
E64.1 Sequelae of vitamin A deficiency
0.000 0.948 0.051
E64.0 Sequelae of protein-energy malnutrition
0.000 0.948 0.051
E34.0 Carcinoid syndrome
0.000 0.948 0.051
E65-E68 Obesity and other hyperalimentation
0.000 0.949 0.051
E55.0 Rickets, active
0.000 0.950 0.050
E22.8 Other hyperfunction of pituitary gland
0.000 0.951 0.049
E22.0 Acromegaly and pituitary gigantism
0.000 0.951 0.049
H40.0 Glaucoma suspect
0.049 0.951 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.952 0.048
E55.9 Vitamin D deficiency, unspecified
0.000 0.953 0.047
E06.4 Drug-induced thyroiditis
0.000 0.954 0.046
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.954 0.046
E06.1 Subacute thyroiditis
0.000 0.954 0.046
E06.0 Acute thyroiditis
0.000 0.954 0.046
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.954 0.046
E44.1 Mild protein-energy malnutrition
0.000 0.954 0.045
E44.0 Moderate protein-energy malnutrition
0.000 0.954 0.045
E22.1 Hyperprolactinaemia
0.000 0.955 0.045
E03.5 Myxoedema coma
0.000 0.955 0.045
E03.4 Atrophy of thyroid (acquired)
0.000 0.955 0.045
E03.3 Postinfectious hypothyroidism
0.000 0.955 0.045
E03.1 Congenital hypothyroidism without goitre
0.000 0.955 0.045
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.955 0.045
E21.3 Hyperparathyroidism, unspecified
0.000 0.956 0.044
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.956 0.044
E06.5 Other chronic thyroiditis
0.000 0.957 0.043
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.957 0.043
E53.1 Pyridoxine deficiency
0.000 0.957 0.043
E53.0 Riboflavin deficiency
0.000 0.957 0.043
E21.4 Other specified disorders of parathyroid gland
0.000 0.957 0.043
E46 Unspecified protein-energy malnutrition
0.000 0.957 0.042
E11.9 Without complications
0.000 0.958 0.042
E21.2 Other hyperparathyroidism
0.000 0.959 0.041
H40.3 Glaucoma secondary to eye trauma
0.041 0.959 0.000
E07.8 Other specified disorders of thyroid
0.000 0.959 0.040
H40.4 Glaucoma secondary to eye inflammation
0.040 0.959 0.000
E83.5 Disorders of calcium metabolism
0.040 0.960 0.000
H40.8 Other glaucoma
0.040 0.960 0.000
H40.6 Glaucoma secondary to drugs
0.039 0.961 0.000
E07.1 Dyshormogenetic goitre
0.000 0.961 0.039
E07.0 Hypersecretion of calcitonin
0.000 0.961 0.039
E27.2 Addisonian crisis
0.000 0.961 0.039
E67 Other hyperalimentation
0.000 0.963 0.037
E68 Sequelae of hyperalimentation
0.000 0.963 0.037
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.965 0.035
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.966 0.034
C43.5 Malignant melanoma of trunk
0.000 0.968 0.032
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.969 0.031
E27.1 Primary adrenocortical insufficiency
0.000 0.970 0.030
C43 Malignant melanoma of skin
0.000 0.972 0.028
H40.9 Glaucoma, unspecified
0.028 0.972 0.000
E65 Localised adiposity
0.000 0.972 0.028
K50-K52 Noninfective enteritis and colitis
0.027 0.973 0.000
E67.8 Other specified hyperalimentation
0.000 0.973 0.027
E67.3 Hypervitaminosis D
0.000 0.973 0.027
E67.2 Megavitamin-B6 syndrome
0.000 0.973 0.027
E67.1 Hypercarotenaemia
0.000 0.973 0.027
E67.0 Hypervitaminosis A
0.000 0.973 0.027
E28.2 Polycystic ovarian syndrome
0.000 0.973 0.026
L30.9 Dermatitis, unspecified
0.026 0.974 0.000
C43.9 Malignant melanoma of skin, unspecified
0.000 0.975 0.025
C77.2 Intra-abdominal lymph nodes
0.025 0.975 0.000
I78.1 Naevus, nonneoplastic
0.024 0.976 0.000
K90-K93 Other diseases of the digestive system
0.001 0.977 0.022
H40-H42 Glaucoma
0.023 0.977 0.000
C43.4 Malignant melanoma of scalp and neck
0.000 0.978 0.022
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.979 0.021
K50 Crohn's disease [regional enteritis]
0.021 0.979 0.000
C43.8 Overlapping malignant melanoma of skin
0.000 0.979 0.020
C43.0 Malignant melanoma of lip
0.000 0.979 0.020
V18.0 Driver injured in nontraffic accident
0.020 0.980 0.000
E06.3 Autoimmune thyroiditis
0.000 0.980 0.020
A08.4 Viral intestinal infection, unspecified
0.000 0.980 0.020
K50.9 Crohn's disease, unspecified
0.020 0.980 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.982 0.018
E53.8 Deficiency of other specified B group vitamins
0.000 0.982 0.018
C43.1 Malignant melanoma of eyelid, including canthus
0.000 0.983 0.017
K93 Disorders of other digestive organs in diseases classified elsewhere
0.001 0.983 0.016
H42 Glaucoma in diseases classified elsewhere
0.016 0.983 0.000
E21.0 Primary hyperparathyroidism
0.000 0.985 0.015
L30 Other dermatitis
0.014 0.986 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.014 0.986 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.986 0.014
E07.9 Disorder of thyroid, unspecified
0.000 0.986 0.014
K50.1 Crohn's disease of large intestine
0.014 0.986 0.000
K50.8 Other Crohn's disease
0.013 0.987 0.000
E04 Other non-toxic goitre
0.000 0.988 0.012
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.001 0.988 0.012
K93.1 Megacolon in Chagas' disease
0.001 0.988 0.012
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.001 0.988 0.012
H42.8 Glaucoma in other diseases classified elsewhere
0.012 0.988 0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases
0.012 0.988 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.988 0.012
L30.3 Infective dermatitis
0.012 0.988 0.000
D52.9 Folate deficiency anaemia, unspecified
0.012 0.988 0.000
H40.1 Primary open-angle glaucoma
0.012 0.988 0.000
L30.4 Erythema intertrigo
0.011 0.988 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.000 0.988 0.012
L30.1 Dyshidrosis [pompholyx]
0.011 0.989 0.000
L30.5 Pityriasis alba
0.010 0.989 0.000
L30.2 Cutaneous autosensitisation
0.010 0.989 0.000
L30.0 Nummular dermatitis
0.010 0.989 0.000
I78 Diseases of capillaries
0.010 0.990 0.000
E04.8 Other specified non-toxic goitre
0.000 0.991 0.009
Q23 Congenital malformations of aortic and mitral valves
0.009 0.991 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.991 0.009
L30.8 Other specified dermatitis
0.009 0.991 0.000
K50.0 Crohn's disease of small intestine
0.009 0.991 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.009 0.991 0.000
S62.3 Fracture of other metacarpal bone
0.000 0.991 0.009
I78.8 Other diseases of capillaries
0.009 0.991 0.000
Q23.0 Congenital stenosis of aortic valve
0.008 0.991 0.000
Q23.1 Congenital insufficiency of aortic valve
0.008 0.992 0.000
H54.0 Blindness, both eyes
0.000 0.992 0.008
Q21 Congenital malformations of cardiac septa
0.008 0.992 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.008 0.992 0.000
I78.9 Disease of capillaries, unspecified
0.008 0.992 0.000
Q28 Other congenital malformations of circulatory system
0.008 0.992 0.000
H54.7 Unspecified visual loss
0.000 0.993 0.007
E66 Obesity
0.000 0.993 0.007
Q21.0 Ventricular septal defect
0.007 0.993 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.000 0.993 0.007
C18.0 Caecum
0.007 0.993 0.000
Q24 Other congenital malformations of heart
0.007 0.993 0.000
Q26 Congenital malformations of great veins
0.007 0.993 0.000
K04.5 Chronic apical periodontitis
0.007 0.993 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.007 0.993 0.000
Q25 Congenital malformations of great arteries
0.007 0.993 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.007 0.993 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.007 0.993 0.000
Q23.8 Other congenital malformations of aortic and mitral valves
0.007 0.993 0.000
Q23.4 Hypoplastic left heart syndrome
0.007 0.993 0.000
Q23.3 Congenital mitral insufficiency
0.007 0.993 0.000
Q23.2 Congenital mitral stenosis
0.007 0.993 0.000
D32.0 Cerebral meninges
0.007 0.993 0.000
Q21.9 Congenital malformation of cardiac septum, unspecified
0.007 0.993 0.000
Q21.3 Tetralogy of Fallot
0.007 0.993 0.000
S62.31 Fracture of other metacarpal bone (open)
0.000 0.993 0.007
H54 Blindness and low vision
0.000 0.993 0.007
Q20 Congenital malformations of cardiac chambers and connexions
0.006 0.993 0.000
V18.1 Passenger injured in nontraffic accident
0.006 0.994 0.000
Q24.0 Dextrocardia
0.006 0.994 0.000
Q24.8 Other specified congenital malformations of heart
0.006 0.994 0.000
Q27 Other congenital malformations of peripheral vascular system
0.006 0.994 0.000
V18.5 Passenger injured in traffic accident
0.006 0.994 0.000
Q21.8 Other congenital malformations of cardiac septa
0.006 0.994 0.000
Q21.4 Aortopulmonary septal defect
0.006 0.994 0.000
Q21.2 Atrioventricular septal defect
0.006 0.994 0.000
Q28.0 Arteriovenous malformation of precerebral vessels
0.006 0.994 0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified
0.006 0.994 0.000
E70-E90 Metabolic disorders
0.006 0.994 0.000
V18.9 Unspecified pedal cyclist injured in traffic accident
0.006 0.994 0.000
V18.4 Driver injured in traffic accident
0.006 0.994 0.000
F10.1 Harmful use
0.006 0.994 0.000
Q28.9 Congenital malformation of circulatory system, unspecified
0.006 0.994 0.000
Q28.8 Other specified congenital malformations of circulatory system
0.006 0.994 0.000
Q28.1 Other malformations of precerebral vessels
0.006 0.994 0.000
E66.1 Drug-induced obesity
0.000 0.994 0.005
E85 Amyloidosis
0.005 0.994 0.000
D52 Folate deficiency anaemia
0.006 0.994 0.000
Q28.3 Other malformations of cerebral vessels
0.005 0.994 0.000
Q24.6 Congenital heart block
0.005 0.994 0.000
Q22.5 Ebstein's anomaly
0.005 0.995 0.000
Q24.4 Congenital subaortic stenosis
0.005 0.995 0.000
Q24.3 Pulmonary infundibular stenosis
0.005 0.995 0.000
Q24.2 Cor triatriatum
0.005 0.995 0.000
Q24.1 Levocardia
0.005 0.995 0.000
Q25.1 Coarctation of aorta
0.005 0.995 0.000
Q26.9 Congenital malformation of great vein, unspecified
0.005 0.995 0.000
Q26.8 Other congenital malformations of great veins
0.005 0.995 0.000
Q26.6 Portal vein-hepatic artery fistula
0.005 0.995 0.000
Q26.5 Anomalous portal venous connexion
0.005 0.995 0.000
Q26.3 Partial anomalous pulmonary venous connexion
0.005 0.995 0.000
Q26.2 Total anomalous pulmonary venous connexion
0.005 0.995 0.000
Q26.1 Persistent left superior vena cava
0.005 0.995 0.000
Q26.0 Congenital stenosis of vena cava
0.005 0.995 0.000
E85.9 Amyloidosis, unspecified
0.005 0.995 0.000
H54.6 Unqualified visual loss, one eye
0.000 0.995 0.005
Q25.4 Other congenital malformations of aorta
0.005 0.995 0.000
H54.9 Unspecified visual impairment (binocular)
0.000 0.995 0.005
V18.3 Person injured while boarding or alighting
0.005 0.995 0.000
Q25.9 Congenital malformation of great arteries, unspecified
0.005 0.995 0.000
Q25.8 Other congenital malformations of great arteries
0.005 0.995 0.000
Q25.7 Other congenital malformations of pulmonary artery
0.005 0.995 0.000
Q25.5 Atresia of pulmonary artery
0.005 0.995 0.000
Q25.3 Stenosis of aorta
0.005 0.995 0.000
Q25.2 Atresia of aorta
0.005 0.995 0.000
E04.0 Non-toxic diffuse goitre
0.001 0.995 0.004
Q22.9 Congenital malformation of tricuspid valve, unspecified
0.005 0.995 0.000
Q22.8 Other congenital malformations of tricuspid valve
0.005 0.995 0.000
Q22.6 Hypoplastic right heart syndrome
0.005 0.995 0.000
Q22.4 Congenital tricuspid stenosis
0.005 0.995 0.000
Q22.3 Other congenital malformations of pulmonary valve
0.005 0.995 0.000
Q22.2 Congenital pulmonary valve insufficiency
0.005 0.995 0.000
Q22.1 Congenital pulmonary valve stenosis
0.005 0.995 0.000
Q22.0 Pulmonary valve atresia
0.005 0.995 0.000
Q25.6 Stenosis of pulmonary artery
0.005 0.995 0.000
Q25.0 Patent ductus arteriosus
0.005 0.995 0.000
Q24.5 Malformation of coronary vessels
0.005 0.995 0.000
Q21.1 Atrial septal defect
0.005 0.995 0.000
H54.3 Unqualified visual loss, both eyes
0.000 0.995 0.005
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.005 0.995 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.005 0.995 0.000
K70.9 Alcoholic liver disease, unspecified
0.005 0.995 0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified
0.005 0.995 0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions
0.005 0.995 0.000
Q20.6 Isomerism of atrial appendages
0.005 0.995 0.000
Q20.5 Discordant atrioventricular connexion
0.005 0.995 0.000
Q20.4 Double inlet ventricle
0.005 0.995 0.000
Q20.3 Discordant ventriculoarterial connexion
0.005 0.995 0.000
Q20.2 Double outlet left ventricle
0.005 0.995 0.000
Q20.1 Double outlet right ventricle
0.005 0.995 0.000
Q20.0 Common arterial trunk
0.005 0.995 0.000
Q27.8 Other specified congenital malformations of peripheral vascular system
0.005 0.995 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.995 0.005
N30.1 Interstitial cystitis (chronic)
0.000 0.995 0.005
A08 Viral and other specified intestinal infections
0.000 0.995 0.005
E70 Disorders of aromatic amino-acid metabolism
0.004 0.995 0.000
H54.5 Low vision, one eye
0.000 0.995 0.005
E88 Other metabolic disorders
0.005 0.995 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.995 0.005
H54.4 Blindness, one eye
0.000 0.995 0.005
E85.3 Secondary systemic amyloidosis
0.005 0.995 0.000
Q24.9 Congenital malformation of the heart, unspecified
0.005 0.995 0.000
Q27.4 Congenital phlebectasia
0.004 0.995 0.000
Q27.2 Other congenital malformations of renal artery
0.004 0.995 0.000
Q27.1 Congenital renal artery stenosis
0.004 0.995 0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery
0.004 0.995 0.000
Q27.3 Peripheral arteriovenous malformation
0.005 0.995 0.000
K70.1 Alcoholic hepatitis
0.005 0.995 0.000
K62.8 Other specified diseases of anus and rectum
0.005 0.995 0.000
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity
0.004 0.995 0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity
0.004 0.995 0.000
E77 Disorders of glycoprotein metabolism
0.004 0.995 0.000
E76 Disorders of glycosaminoglycan metabolism
0.004 0.995 0.000
E72 Other disorders of amino-acid metabolism
0.004 0.995 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.004 0.995 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.004 0.995 0.000
H54.2 Low vision, both eyes
0.000 0.995 0.004
E84 Cystic fibrosis
0.004 0.995 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.004 0.995 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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