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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3093995
log Bayes Factor = 65.0819
Chromosome 6   position 31,488,904  (GRCh37) Explore rs3093995 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.001 0.999
I25.1 Atherosclerotic heart disease
0.000 0.001 0.999
I20 Angina pectoris
0.000 0.004 0.996
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.005 0.995
E14.9 Without complications
0.000 0.011 0.989
E14.3 With ophthalmic complications
0.000 0.012 0.988
E10.1 With ketoacidosis
0.000 0.013 0.987
I25.5 Ischaemic cardiomyopathy
0.000 0.013 0.987
I20.9 Angina pectoris, unspecified
0.000 0.014 0.986
E10.4 With neurological complications
0.000 0.018 0.982
I22 Subsequent myocardial infarction
0.000 0.019 0.981
I20.0 Unstable angina
0.000 0.025 0.975
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.028 0.972
G35-G37 Demyelinating diseases of the central nervous system
0.966 0.034 0.000
I25.2 Old myocardial infarction
0.000 0.039 0.961
G37 Other demyelinating diseases of central nervous system
0.960 0.040 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.047 0.953
E83.1 Disorders of iron metabolism
0.952 0.048 0.000
I21 Acute myocardial infarction
0.000 0.049 0.951
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.055 0.945
G37.9 Demyelinating disease of central nervous system, unspecified
0.943 0.057 0.000
R07.4 Chest pain, unspecified
0.000 0.063 0.937
E70-E90 Metabolic disorders
0.000 0.064 0.936
E13 Other specified diabetes mellitus
0.000 0.065 0.935
I21.9 Acute myocardial infarction, unspecified
0.000 0.081 0.919
I10 Essential (primary) hypertension
0.000 0.084 0.916
L40-L45 Papulosquamous disorders
0.000 0.088 0.912
L43 Lichen planus
0.000 0.109 0.891
I24 Other acute ischaemic heart diseases
0.000 0.111 0.889
E13.9 Without complications
0.000 0.112 0.888
E78.8 Other disorders of lipoprotein metabolism
0.000 0.113 0.887
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.116 0.884
E11.2 With renal complications
0.000 0.116 0.884
E10.2 With renal complications
0.000 0.118 0.881
E00-E07 Disorders of thyroid gland
0.000 0.126 0.874
L43.9 Lichen planus, unspecified
0.000 0.132 0.868
E11.0 With coma
0.000 0.135 0.864
E11.1 With ketoacidosis
0.000 0.153 0.847
E03 Other hypothyroidism
0.000 0.157 0.843
G37.8 Other specified demyelinating diseases of central nervous system
0.842 0.158 0.000
L40.8 Other psoriasis
0.000 0.159 0.841
I10-I15 Hypertensive diseases
0.000 0.160 0.840
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.164 0.836
E03.9 Hypothyroidism, unspecified
0.000 0.167 0.833
I21.4 Acute subendocardial myocardial infarction
0.000 0.167 0.833
I25.3 Aneurysm of heart
0.000 0.176 0.824
E14.4 With neurological complications
0.000 0.176 0.824
E10.8 With unspecified complications
0.000 0.181 0.819
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.182 0.818
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.186 0.814
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.198 0.802
E10.5 With peripheral circulatory complications
0.000 0.203 0.797
E10.0 With coma
0.000 0.207 0.793
I23 Certain current complications following acute myocardial infarction
0.000 0.212 0.788
E78.2 Mixed hyperlipidaemia
0.000 0.212 0.788
E05.9 Thyrotoxicosis, unspecified
0.000 0.213 0.787
L40.0 Psoriasis vulgaris
0.000 0.223 0.777
E85 Amyloidosis
0.000 0.229 0.771
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.769 0.231 0.000
E11.6 With other specified complications
0.000 0.231 0.768
E16 Other disorders of pancreatic internal secretion
0.000 0.242 0.758
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.242 0.758
I24.8 Other forms of acute ischaemic heart disease
0.000 0.258 0.742
E78.6 Lipoprotein deficiency
0.000 0.262 0.738
I15 Secondary hypertension
0.000 0.262 0.738
L43.8 Other lichen planus
0.000 0.264 0.736
E14.5 With peripheral circulatory complications
0.000 0.266 0.734
E10.6 With other specified complications
0.000 0.266 0.734
E74 Other disorders of carbohydrate metabolism
0.000 0.270 0.729
E11.5 With peripheral circulatory complications
0.000 0.274 0.726
E14.6 With other specified complications
0.000 0.279 0.721
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.284 0.716
I12 Hypertensive renal disease
0.000 0.286 0.714
E78.1 Pure hyperglyceridaemia
0.000 0.292 0.708
E78.3 Hyperchylomicronaemia
0.000 0.303 0.697
G36 Other acute disseminated demyelination
0.696 0.304 0.000
G37.5 Concentric sclerosis [Balo]
0.688 0.312 0.000
G37.4 Subacute necrotising myelitis
0.688 0.312 0.000
G37.2 Central pontine myelinolysis
0.688 0.312 0.000
G37.1 Central demyelination of corpus callosum
0.688 0.312 0.000
G37.0 Diffuse sclerosis
0.688 0.312 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.314 0.686
L40.3 Pustulosis palmaris et plantaris
0.000 0.317 0.683
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.318 0.682
L42 Pityriasis rosea
0.000 0.323 0.677
E79 Disorders of purine and pyrimidine metabolism
0.000 0.328 0.672
E77 Disorders of glycoprotein metabolism
0.000 0.329 0.671
E76 Disorders of glycosaminoglycan metabolism
0.000 0.329 0.671
E72 Other disorders of amino-acid metabolism
0.000 0.329 0.671
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.329 0.671
E70 Disorders of aromatic amino-acid metabolism
0.000 0.329 0.671
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.329 0.671
E13.8 With unspecified complications
0.000 0.330 0.670
E13.7 With multiple complications
0.000 0.330 0.670
E13.6 With other specified complications
0.000 0.330 0.670
E13.5 With peripheral circulatory complications
0.000 0.330 0.670
E13.4 With neurological complications
0.000 0.330 0.670
E13.3 With ophthalmic complications
0.000 0.330 0.670
E13.2 With renal complications
0.000 0.330 0.670
E13.1 With ketoacidosis
0.000 0.330 0.670
E13.0 With coma
0.000 0.330 0.670
I15.1 Hypertension secondary to other renal disorders
0.000 0.332 0.668
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.338 0.662
E78.4 Other hyperlipidaemia
0.000 0.340 0.660
I22.8 Subsequent myocardial infarction of other sites
0.000 0.342 0.658
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.345 0.655
L44 Other papulosquamous disorders
0.000 0.346 0.654
L41 Parapsoriasis
0.000 0.346 0.654
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.346 0.654
E85.9 Amyloidosis, unspecified
0.000 0.347 0.653
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.350 0.650
I11 Hypertensive heart disease
0.000 0.360 0.640
L43.3 Subacute (active) lichen planus
0.000 0.361 0.639
L43.2 Lichenoid drug reaction
0.000 0.361 0.639
L43.1 Bullous lichen planus
0.000 0.361 0.639
L43.0 Hypertrophic lichen planus
0.000 0.361 0.639
I12.9 Hypertensive renal disease without renal failure
0.000 0.363 0.637
I23.8 Other current complications following acute myocardial infarction
0.000 0.364 0.636
I20.1 Angina pectoris with documented spasm
0.000 0.369 0.631
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.373 0.627
E00 Congenital iodine-deficiency syndrome
0.000 0.373 0.627
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.375 0.625
E78.5 Hyperlipidaemia, unspecified
0.000 0.383 0.617
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.383 0.617
E84 Cystic fibrosis
0.000 0.385 0.614
E03.5 Myxoedema coma
0.000 0.395 0.604
E03.4 Atrophy of thyroid (acquired)
0.000 0.395 0.604
E03.3 Postinfectious hypothyroidism
0.000 0.395 0.604
E03.1 Congenital hypothyroidism without goitre
0.000 0.395 0.604
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.395 0.604
I13 Hypertensive heart and renal disease
0.000 0.398 0.602
I25.4 Coronary artery aneurysm
0.000 0.400 0.600
E15 Nondiabetic hypoglycaemic coma
0.000 0.400 0.599
E40-E46 Malnutrition
0.000 0.402 0.597
E16.1 Other hypoglycaemia
0.000 0.404 0.596
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.406 0.594
E05.5 Thyroid crisis or storm
0.000 0.413 0.587
E05.4 Thyrotoxicosis factitia
0.000 0.413 0.587
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.413 0.587
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.413 0.587
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.419 0.581
E11.4 With neurological complications
0.000 0.419 0.581
E07 Other disorders of thyroid
0.000 0.423 0.577
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.435 0.565
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.435 0.565
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.435 0.565
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.435 0.565
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.435 0.565
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.435 0.565
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.435 0.565
E85.4 Organ-limited amyloidosis
0.000 0.437 0.562
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.443 0.557
E73 Lactose intolerance
0.000 0.446 0.554
E85.8 Other amyloidosis
0.000 0.447 0.552
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.447 0.552
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.447 0.552
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.447 0.552
Chapter IX Diseases of the circulatory system
0.000 0.450 0.550
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.456 0.544
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.456 0.544
E16.4 Abnormal secretion of gastrin
0.000 0.456 0.544
E16.3 Increased secretion of glucagon
0.000 0.456 0.544
E85.3 Secondary systemic amyloidosis
0.000 0.459 0.541
E89.3 Postprocedural hypopituitarism
0.000 0.460 0.540
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.461 0.539
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.469 0.531
I15.8 Other secondary hypertension
0.000 0.471 0.529
I15.2 Hypertension secondary to endocrine disorders
0.000 0.471 0.529
I15.0 Renovascular hypertension
0.000 0.471 0.529
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.472 0.528
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.477 0.523
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.477 0.523
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.477 0.523
E74.2 Disorders of galactose metabolism
0.000 0.477 0.523
E74.1 Disorders of fructose metabolism
0.000 0.477 0.523
E74.0 Glycogen storage disease
0.000 0.477 0.523
I15.9 Seconday hypertension, unspecified
0.000 0.482 0.518
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.482 0.517
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E06 Thyroiditis
0.000 0.488 0.512
I24.1 Dressler's syndrome
0.000 0.493 0.506
E11.3 With ophthalmic complications
0.000 0.494 0.506
G36.0 Neuromyelitis optica [Devic]
0.503 0.497 0.000
E11.8 With unspecified complications
0.000 0.500 0.500
G36.9 Acute disseminated demyelination, unspecified
0.499 0.501 0.000
G36.8 Other specified acute disseminated demyelination
0.499 0.501 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.499 0.501 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.504 0.496
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.518 0.482
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.518 0.482
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.518 0.482
E79.1 Lesch-Nyhan syndrome
0.000 0.518 0.482
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.519 0.481
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.519 0.481
E70.3 Albinism
0.000 0.519 0.481
E70.2 Disorders of tyrosine metabolism
0.000 0.519 0.481
E70.1 Other hyperphenylalaninaemias
0.000 0.519 0.481
E70.0 Classical phenylketonuria
0.000 0.519 0.481
E71.3 Disorders of fatty-acid metabolism
0.000 0.519 0.481
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.519 0.481
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.519 0.481
E71.0 Maple-syrup-urine disease
0.000 0.519 0.481
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.519 0.481
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.519 0.481
E72.5 Disorders of glycine metabolism
0.000 0.519 0.481
E72.4 Disorders of ornithine metabolism
0.000 0.519 0.481
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.519 0.481
E72.2 Disorders of urea cycle metabolism
0.000 0.519 0.481
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.519 0.481
E72.0 Disorders of amino-acid transport
0.000 0.519 0.481
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.519 0.481
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.519 0.481
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.519 0.481
E76.2 Other mucopolysaccharidoses
0.000 0.519 0.481
E76.1 Mucopolysaccharidosis, type II
0.000 0.519 0.481
E76.0 Mucopolysaccharidosis, type I
0.000 0.519 0.481
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.519 0.481
E77.8 Other disorders of glycoprotein metabolism
0.000 0.519 0.481
E77.1 Defects in glycoprotein degradation
0.000 0.519 0.481
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.519 0.481
I12.0 Hypertensive renal disease with renal failure
0.000 0.519 0.481
E05.8 Other thyrotoxicosis
0.000 0.519 0.480
E88 Other metabolic disorders
0.000 0.524 0.476
E75.6 Lipid storage disorder, unspecified
0.000 0.525 0.474
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.525 0.474
E75.3 Sphingolipidosis, unspecified
0.000 0.525 0.474
E75.2 Other sphingolipidosis
0.000 0.525 0.474
E75.1 Other gangliosidosis
0.000 0.525 0.474
E75.0 GM2 gangliosidosis
0.000 0.525 0.474
E83 Disorders of mineral metabolism
0.328 0.528 0.144
L41.9 Parapsoriasis, unspecified
0.000 0.531 0.469
L41.8 Other parapsoriasis
0.000 0.531 0.469
L41.5 Retiform parapsoriasis
0.000 0.531 0.469
L41.4 Large plaque parapsoriasis
0.000 0.531 0.469
L41.3 Small plaque parapsoriasis
0.000 0.531 0.469
L41.2 Lymphomatoid papulosis
0.000 0.531 0.469
L41.1 Pityriasis lichenoides chronica
0.000 0.531 0.469
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.531 0.469
L44.9 Papulosquamous disorder, unspecified
0.000 0.531 0.469
L44.8 Other specified papulosquamous disorders
0.000 0.531 0.469
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.531 0.469
L44.3 Lichen ruber moniliformis
0.000 0.531 0.469
L44.2 Lichen striatus
0.000 0.531 0.469
L44.1 Lichen nitidus
0.000 0.531 0.469
L44.0 Pityriasis rubra pilaris
0.000 0.531 0.469
E75.5 Other lipid storage disorders
0.000 0.534 0.465
E65-E68 Obesity and other hyperalimentation
0.000 0.547 0.453
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.550 0.449
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.550 0.449
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.550 0.449
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.550 0.449
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.550 0.449
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.550 0.449
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.550 0.449
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.550 0.449
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.558 0.442
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.558 0.442
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.558 0.442
E89.5 Postprocedural testicular hypofunction
0.000 0.558 0.442
E89.1 Postprocedural hypoinsulinaemia
0.000 0.558 0.442
E84.8 Cystic fibrosis with other manifestations
0.000 0.559 0.440
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.559 0.440
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.559 0.440
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.568 0.432
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.568 0.432
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.568 0.432
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.568 0.432
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.571 0.428
E45 Retarded development following protein-energy malnutrition
0.000 0.571 0.428
E43 Unspecified severe protein-energy malnutrition
0.000 0.571 0.428
E42 Marasmic kwashiorkor
0.000 0.571 0.428
E41 Nutritional marasmus
0.000 0.571 0.428
E40 Kwashiorkor
0.000 0.571 0.428
E50-E64 Other nutritional deficiencies
0.000 0.576 0.423
E89.4 Postprocedural ovarian failure
0.000 0.585 0.415
E07.1 Dyshormogenetic goitre
0.000 0.586 0.414
E07.0 Hypersecretion of calcitonin
0.000 0.586 0.414
E07.8 Other specified disorders of thyroid
0.000 0.588 0.412
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.597 0.403
K90 Intestinal malabsorption
0.000 0.598 0.402
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.599 0.400
E73.8 Other lactose intolerance
0.000 0.602 0.397
E73.1 Secondary lactase deficiency
0.000 0.602 0.397
E73.0 Congenital lactase deficiency
0.000 0.602 0.397
I00-I02 Acute rheumatic fever
0.000 0.606 0.394
E89.2 Postprocedural hypoparathyroidism
0.000 0.610 0.390
E84.9 Cystic fibrosis, unspecified
0.000 0.616 0.384
E88.2 Lipomatosis, not elsewhere classified
0.000 0.618 0.382
E80.6 Other disorders of bilirubin metabolism
0.000 0.627 0.372
E07.9 Disorder of thyroid, unspecified
0.000 0.633 0.367
E06.5 Other chronic thyroiditis
0.000 0.633 0.367
E06.4 Drug-induced thyroiditis
0.000 0.633 0.367
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.633 0.367
E06.1 Subacute thyroiditis
0.000 0.633 0.367
E06.0 Acute thyroiditis
0.000 0.633 0.367
E03.8 Other specified hypothyroidism
0.001 0.643 0.357
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.644 0.356
E80.5 Crigler-Najjar syndrome
0.000 0.644 0.356
E80.3 Defects of catalase and peroxydase
0.000 0.644 0.356
E80.2 Other porphyria
0.000 0.644 0.356
E80.1 Porphyria cutanea tarda
0.000 0.644 0.356
E80.0 Hereditary erythropoietic porphyria
0.000 0.644 0.356
E46 Unspecified protein-energy malnutrition
0.000 0.652 0.348
E06.9 Thyroiditis, unspecified
0.000 0.652 0.348
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.654 0.346
E88.8 Other specified metabolic disorders
0.000 0.657 0.343
E88.9 Metabolic disorder, unspecified
0.000 0.658 0.341
E83.9 Disorder of mineral metabolism, unspecified
0.235 0.661 0.103
E83.8 Other disorders of mineral metabolism
0.235 0.661 0.103
E83.2 Disorders of zinc metabolism
0.235 0.661 0.103
E83.0 Disorders of copper metabolism
0.235 0.661 0.103
E88.3 Tumour lysis syndrome
0.000 0.662 0.338
E67 Other hyperalimentation
0.000 0.675 0.325
E68 Sequelae of hyperalimentation
0.000 0.675 0.325
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.677 0.323
E83.3 Disorders of phosphorus metabolism
0.271 0.678 0.051
E61 Deficiency of other nutrient elements
0.000 0.678 0.322
E65 Localised adiposity
0.000 0.684 0.316
E44.1 Mild protein-energy malnutrition
0.000 0.693 0.307
E44.0 Moderate protein-energy malnutrition
0.000 0.693 0.307
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.696 0.304
E63 Other nutritional deficiencies
0.000 0.696 0.304
E56 Other vitamin deficiencies
0.000 0.696 0.304
E51 Thiamine deficiency
0.000 0.696 0.304
E50 Vitamin A deficiency
0.000 0.696 0.304
E60 Dietary zinc deficiency
0.000 0.696 0.304
E59 Dietary selenium deficiency
0.000 0.696 0.304
E58 Dietary calcium deficiency
0.000 0.696 0.304
E54 Ascorbic acid deficiency
0.000 0.696 0.304
E52 Niacin deficiency [pellagra]
0.000 0.696 0.304
K90.9 Intestinal malabsorption, unspecified
0.000 0.711 0.289
K90.3 Pancreatic steatorrhoea
0.000 0.712 0.288
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.712 0.288
K90.1 Tropical sprue
0.000 0.712 0.288
K90.8 Other intestinal malabsorption
0.000 0.712 0.288
I02 Rheumatic chorea
0.000 0.717 0.283
I01 Rheumatic fever with heart involvement
0.000 0.717 0.283
I00 Rheumatic fever without mention of heart involvement
0.000 0.717 0.283
E20-E35 Disorders of other endocrine glands
0.000 0.718 0.282
E06.3 Autoimmune thyroiditis
0.000 0.718 0.282
E73.9 Lactose intolerance, unspecified
0.001 0.719 0.280
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.724 0.275
E89.0 Postprocedural hypothyroidism
0.000 0.731 0.269
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.742 0.258
E61.1 Iron deficiency
0.000 0.744 0.256
E55 Vitamin D deficiency
0.000 0.759 0.240
E23 Hypofunction and other disorders of pituitary gland
0.000 0.766 0.234
E67.8 Other specified hyperalimentation
0.000 0.767 0.233
E67.3 Hypervitaminosis D
0.000 0.767 0.233
E67.2 Megavitamin-B6 syndrome
0.000 0.767 0.233
E67.1 Hypercarotenaemia
0.000 0.767 0.233
E67.0 Hypervitaminosis A
0.000 0.767 0.233
E61.9 Deficiency of nutrient element, unspecified
0.000 0.769 0.231
E61.8 Deficiency of other specified nutrient elements
0.000 0.769 0.231
E61.7 Deficiency of multiple nutrient elements
0.000 0.769 0.231
E61.6 Vanadium deficiency
0.000 0.769 0.231
E61.5 Molybdenum deficiency
0.000 0.769 0.231
E61.4 Chromium deficiency
0.000 0.769 0.231
E61.3 Manganese deficiency
0.000 0.769 0.231
E61.0 Copper deficiency
0.000 0.769 0.231
E22 Hyperfunction of pituitary gland
0.000 0.777 0.223
E61.2 Magnesium deficiency
0.000 0.779 0.221
E50.9 Vitamin A deficiency, unspecified
0.000 0.782 0.218
E50.8 Other manifestations of vitamin A deficiency
0.000 0.782 0.218
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.782 0.218
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.782 0.218
E50.5 Vitamin A deficiency with night blindness
0.000 0.782 0.218
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.782 0.218
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.782 0.218
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.782 0.218
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.782 0.218
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.782 0.218
E51.9 Thiamine deficiency, unspecified
0.000 0.782 0.218
E51.8 Other manifestations of thiamine deficiency
0.000 0.782 0.218
E51.2 Wernicke's encephalopathy
0.000 0.782 0.218
E51.1 Beriberi
0.000 0.782 0.218
E56.9 Vitamin deficiency, unspecified
0.000 0.782 0.218
E56.8 Deficiency of other vitamins
0.000 0.782 0.218
E56.1 Deficiency of vitamin K
0.000 0.782 0.218
E56.0 Deficiency of vitamin E
0.000 0.782 0.218
E63.9 Nutritional deficiency, unspecified
0.000 0.782 0.218
E63.8 Other specified nutritional deficiencies
0.000 0.782 0.218
E63.1 Imbalance of constituents of food intake
0.000 0.782 0.218
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.782 0.218
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.782 0.218
E64.8 Sequelae of other nutritional deficiencies
0.000 0.782 0.218
E64.3 Sequelae of rickets
0.000 0.782 0.218
E64.2 Sequelae of vitamin C deficiency
0.000 0.782 0.218
E64.1 Sequelae of vitamin A deficiency
0.000 0.782 0.218
E64.0 Sequelae of protein-energy malnutrition
0.000 0.782 0.218
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.791 0.208
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.797 0.203
I01.8 Other acute rheumatic heart disease
0.000 0.797 0.203
I01.2 Acute rheumatic myocarditis
0.000 0.797 0.203
I01.1 Acute rheumatic endocarditis
0.000 0.797 0.203
I01.0 Acute rheumatic pericarditis
0.000 0.797 0.203
I02.9 Rheumatic chorea without heart involvement
0.000 0.797 0.203
I02.0 Rheumatic chorea with heart involvement
0.000 0.797 0.203
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.797 0.202
E32 Diseases of thymus
0.000 0.797 0.202
E31 Polyglandular dysfunction
0.000 0.797 0.202
E30 Disorders of puberty, not elsewhere classified
0.000 0.797 0.202
E25 Adrenogenital disorders
0.000 0.797 0.202
E83.4 Disorders of magnesium metabolism
0.108 0.799 0.094
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.801 0.199
E26 Hyperaldosteronism
0.000 0.802 0.198
E23.6 Other disorders of pituitary gland
0.000 0.804 0.196
E23.2 Diabetes insipidus
0.000 0.809 0.191
E29 Testicular dysfunction
0.000 0.810 0.190
E24 Cushing's syndrome
0.000 0.811 0.189
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.811 0.189
E20 Hypoparathyroidism
0.000 0.818 0.182
E23.7 Disorder of pituitary gland, unspecified
0.000 0.822 0.177
E55.0 Rickets, active
0.000 0.827 0.172
E28 Ovarian dysfunction
0.000 0.830 0.170
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.832 0.168
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.832 0.168
E23.1 Drug-induced hypopituitarism
0.000 0.832 0.168
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.001 0.833 0.166
E21.3 Hyperparathyroidism, unspecified
0.000 0.838 0.162
E22.1 Hyperprolactinaemia
0.000 0.839 0.160
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.840 0.160
E22.8 Other hyperfunction of pituitary gland
0.000 0.840 0.160
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.841 0.159
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.849 0.151
I28 Other diseases of pulmonary vessels
0.001 0.852 0.147
E34 Other endocrine disorders
0.000 0.854 0.146
E25.9 Adrenogenital disorder, unspecified
0.000 0.854 0.145
E25.8 Other adrenogenital disorders
0.000 0.854 0.145
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.854 0.145
E30.9 Disorder of puberty, unspecified
0.000 0.854 0.145
E30.8 Other disorders of puberty
0.000 0.854 0.145
E30.1 Precocious puberty
0.000 0.854 0.145
E30.0 Delayed puberty
0.000 0.854 0.145
E31.9 Polyglandular dysfunction, unspecified
0.000 0.854 0.145
E31.8 Other polyglandular dysfunction
0.000 0.854 0.145
E31.1 Polyglandular hyperfunction
0.000 0.854 0.145
E31.0 Autoimmune polyglandular failure
0.000 0.854 0.145
E32.9 Disease of thymus, unspecified
0.000 0.854 0.145
E32.8 Other diseases of thymus
0.000 0.854 0.145
E32.1 Abscess of thymus
0.000 0.854 0.145
E32.0 Persistent hyperplasia of thymus
0.000 0.854 0.145
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.854 0.145
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.854 0.145
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.854 0.145
E22.0 Acromegaly and pituitary gigantism
0.000 0.855 0.145
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.857 0.143
E21.4 Other specified disorders of parathyroid gland
0.000 0.857 0.143
E21.2 Other hyperparathyroidism
0.000 0.857 0.143
E26.9 Hyperaldosteronism, unspecified
0.000 0.857 0.142
E26.8 Other hyperaldosteronism
0.000 0.857 0.142
E26.1 Secondary hyperaldosteronism
0.000 0.857 0.142
E83.5 Disorders of calcium metabolism
0.109 0.861 0.030
E80.4 Gilbert's syndrome
0.001 0.861 0.138
E26.0 Primary hyperaldosteronism
0.000 0.862 0.138
E29.9 Testicular dysfunction, unspecified
0.000 0.864 0.136
E29.8 Other testicular dysfunction
0.000 0.864 0.136
E29.0 Testicular hyperfunction
0.000 0.864 0.136
E53 Deficiency of other B group vitamins
0.001 0.864 0.135
E24.8 Other Cushing's syndrome
0.000 0.864 0.135
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.864 0.135
E24.3 Ectopic ACTH syndrome
0.000 0.864 0.135
E24.2 Drug-induced Cushing's syndrome
0.000 0.864 0.135
E24.1 Nelson's syndrome
0.000 0.864 0.135
E24.0 Pituitary-dependent Cushing's disease
0.000 0.864 0.135

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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